Science topic

Polymethyl Methacrylate - Science topic

Polymerized methyl methacrylate monomers which are used as sheets, moulding, extrusion powders, surface coating resins, emulsion polymers, fibers, inks, and films (From International Labor Organization, 1983). This material is also used in tooth implants, bone cements, and hard corneal contact lenses.
Questions related to Polymethyl Methacrylate
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I need to spin coat the solution so it needs to be less viscous. My guide suggested me to add some ethanol and stir it for some while but it is still viscous. Should I add more solvent and stir.
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Adding ethanol to a viscous HAP sol can effectively reduce its viscosity, making it suitable for spin coating. However, be cautious not to overly dilute the sol, as this might compromise the film's quality and stability after coating.
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Hi Everyone,
I am performing free radical polymerization of MMA using AIBN as an initiator and DMF as a solvent (I NEED TO USE A SOLVENT AS IT IS REQUIRED OF THE PROJECT NEXT STEP).
I varied AIBN ,REACTION TIME AND TEMPERATURE FOR THE OPTIMIZATION OF PMMA Molecular weight. Does the amount of DMF as a solvent has any effect on the Molecualr weight of the PMMA? I am using 20ml dmf, 10ml of MMA and 60 mg of AIBN AND REACTION TIME IS 24 HOURS. WHAT IF I CHANGE DMF FROM 20ML TO 40 ML WILL THIS EFFECT MY POLYMER MW WHILE HAVING THE SAME CONDITION?
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Hi. The explanation of Zhen is correct. However, if you want to have the same MW, polymerize MMA with 20 ML solvent and dilute the resulting polymer solution after polymerization.
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I have been using Gromacs 2021.7. I wanted to simulate two small molecules in water. But, while generating the ions.tpr, I am getting the following error. The topol.top and .itp files for each molecule are given below.
Fatal error: Syntax error - File receptor.itp, line 8 Last line read: ‘[ atomtypes ] ’ Invalid order for directive atomtypes’
My topol.top file looks like below:
; Include forcefield parameters #include “charmm27.ff/forcefield.itp”
; Include drg topology #include “DRG.itp”
; Include lig topolgy #include “LIG.itp”
; Include water topology #include “charmm27.ff/tip3p.itp”
#ifdef POSRES_WATER ; Position restraint for each water oxygen [ position_restraints ] ; i funct fcx fcy fcz 1 1 1000 1000 1000 #endif
; Include topology for ions #include “charmm27.ff/ions.itp”
[ system ] ; Name System in water
[ molecules ] ; Compound #mols LIG 1 DRG 1 SOL 6436
The two .itp files mentioned for those two molecules are attached.
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The error arises because the [ atomtypes ] directive should be placed before other directives in the topology files. To fix this:
  1. Rearrange the order: Ensure [ atomtypes ] comes before other directives (e.g., [ molecules ], [ system ]) in your .itp files.
  2. Correct syntax: Double-check that all necessary parameters are defined correctly for atom types.
All of which can be easily done at mdsim360.com, a new platform that lets you run MD simulations entirely online without local installation.
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Introduction
In complete edentulous patients, particularly those who have recently undergone extractions, significant differences in the anatomical and biomechanical properties of the maxilla and mandible influence denture design. The mandibular mucosa is thinner, more fragile, and less resilient compared to the maxilla. Additionally, mandibular bone has reduced vascularity, higher density, and increased susceptibility to resorption under pressure. This creates unique challenges in mandibular denture fabrication, particularly in maintaining stability and reducing tissue trauma.
The incorporation of soft liners as an interface material in dentures has been proposed to mitigate these challenges by redistributing forces, reducing pressure points, and enhancing patient comfort. This discussion explores the advantages, limitations, and future potential of soft liners in mandibular dentures.
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Anatomical and Biomechanical Considerations
1. Mandibular Challenges:
The mandibular ridge is more prone to resorption under pressure due to its dense structure and limited vascularity.
Areas such as the labial and distolingual regions are particularly sensitive to pressure, often requiring modification of the denture base, which may compromise seal and retention.
2. Maxillary Advantages:
In contrast, the maxilla often benefits from undercuts that contribute to retention without causing significant discomfort. The mucosal properties also enhance the seal and support of the denture.
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Soft Liners: Properties and Applications
Soft liners are categorized into two main types: acrylic-based and silicone-based, each with distinct properties and limitations.
1. Acrylic-Based Soft Liners:
Derived from poly(methyl methacrylate) (PMMA) with added plasticizers.
Advantages:
Good adhesion to the acrylic denture base.
Effective in temporary applications.
Limitations:
Plasticizers leach out over time, leading to hardening, porosity, and bacterial colonization.
Short lifespan and odor development due to fluid absorption.
2. Silicone-Based Soft Liners:
Composed of dense, non-porous silicone materials.
Advantages:
Superior durability and elasticity.
Capable of distributing forces evenly with moderate thickness.
Resists hardening over time.
Limitations:
Poor adhesion to the acrylic base, leading to potential microleakage.
Microorganism accumulation in the interface.
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Challenges in Silicone Liner Integration
The primary obstacle in utilizing silicone liners effectively is achieving strong, long-lasting adhesion to the denture base. The hydrophobic and dense nature of silicone resists chemical bonding with PMMA. This results in:
Separation of the liner from the base.
Microbial infiltration at the interface.
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Potential Solutions
1. Adhesive Primers:
Application of specialized primers can enhance chemical bonding between silicone and acrylic, improving liner retention.
2. Hybrid Materials:
Development of hybrid soft liner materials combining silicone flexibility with acrylic adhesion properties.
3. Advanced Fabrication Techniques:
Utilization of 3D printing technologies to create custom-designed dentures with integrated liner materials, ensuring uniform thickness and precision.
4. Antimicrobial Modifications:
Incorporating antimicrobial agents (e.g., silver nanoparticles) in silicone liners to reduce bacterial growth at the interface.
5. Localized Application:
Partial application of soft liners in high-pressure areas (e.g., labial and distolingual) to balance flexibility and retention.
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Clinical Recommendations
1. Pre-Denture Tissue Conditioning:
Employ soft tissue conditioning techniques to prepare the mandibular ridge before denture fabrication.
2. Trial Use of Temporary Liners:
Use temporary soft liners to assess patient tolerance and make necessary adjustments before final fabrication.
3. Combination of Rigid and Flexible Materials:
Design dentures that combine rigid bases with flexible liners for optimized performance in specific regions.
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Conclusion
Soft liners represent a valuable tool in addressing the unique challenges of mandibular denture fabrication. Acrylic-based liners are suitable for short-term applications, while silicone liners offer long-term benefits if issues with adhesion and microbial infiltration are resolved. Advances in material science, such as hybrid formulations, and manufacturing techniques like 3D printing, have the potential to establish soft liners as an integral component of modern denture prosthetics.
Further research is needed to optimize the integration of soft liners in mandibular dentures and address existing challenges, particularly in adhesion and microbial resistance.
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Keywords
Soft liners
Acrylic-based liners
Silicone-based liners
Mandibular dentures
Tissue conditioning
Denture retention
Prosthetic materials
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This discussion is prepared to foster academic exchange on ResearchGate, encouraging collaboration on material innovations and clinical applications in denture prosthetics.
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Our researchers studied the prospects of using soft pads for removable dentures. It was determined that for a prosthesis with complete adentia, an important factor is whether the prosthesis was made before tooth extraction or delayed after tooth extraction. This is due to large changes in bone volume in the first 3 months after removal.
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I am doing my research on seafood packaging materials. I have seen lots of research articles on various polymers used for seafood packaging including PEG and PS but there were only 1 or 2 articles where they used PMMA for seafood packaging. I had also seen somewhere that PMMA has been blocked by the FDA to be used for seafood packaging due to migration issues. Am I right here? Please help. Thanks
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Serge V. Shil’ko Thank you so much for the recommendation but in the literature review, you have not mentioned anything about PEG or PMMA. My question was related to only PMMA. If you know whether PMMA is used for seafood packaging or not, I would truly appreciate it. Thank you so much.
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I usually use Raman spectroscopy to characterize graphene peak and I have issues about Raman peak shift during the analysis. I have two problems during the Raman work.
1. I usually collect data several times (2-3times) at the same spot just to make sure the datas I collected are trustworthy. But every data at the same spot with nothing (power, location, etc,.) changed has different wavenumber.
2. I mostly used the spectroscopy to track the state of the graphene. Like the peak shift of graphene due to acetone (which is known to cause p-doping), PMMA spin coated graphene and lastly PMMA removed graphene because as I did some research about them, the cleaner the graphene is, red shift must occur (towards the prisitne graphene). But the theory doesnt work for me. It does not have any tendency.
I wonder if anybody has same issues like i have.
I am guessing this problems are caused due to
1) old device (Witec alpha 300M+)
2) bad focusing of laser
3) I use exfoliated graphene which is composed of many different layers around the spot i focused on (I dont know whether it matters)
4) Lastly, the power. The device's power management of laser is done through nobe not by giving numbers to the program and therefore the power won't be exactly the same. (I raise power where the peak saturation occurs through oscilloscope) <- but how can this matter when i just click "single spectrum" at the same spot but still acquires data with different wavenumber of the same peak.
If anybody had problems like i dave and knows what might be the problem, any advice will be really appreciated. Thanks.
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I've had that with photochemically active material more than one time. If the laser induces structural changes in the material, which may even manifest in changes of morphology visible in optical microscopy, random shifts or appearance of peaks may happen.
Since you are just inspecting graphene, the amount of photochemistry should be limited for large flakes, but if you have nano-sized flakes whose termination would allow photopolymerization, that might be what's happening.
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I want to make a thin film from PMMA in CHCl3 solution with a 200 mg/ml concentration. The PMMA dissolved well in CHCl3 and it was optically clear and transparent, but the thin film was opaque. I use spin coating with 3000 rpm for 30 seconds. Moreover, the last droplet, which remains in the tip, becomes milky and not transparent. Does anyone know what is the reason, and how I can get the transparent thin film? I prefer to get the transparent thin film by Chloroform and no other solvent.
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hello did you find any solution? please inform us if do
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Hello everyone,
I’m currently working on transferring a 2D material onto a new substrate using PMMA as a transfer agent. After successfully transferring the 2D material, I attempted to remove the PMMA by etching it with acetone, but the PMMA remains largely intact, and the etching is not progressing as expected.
Has anyone encountered a similar issue with PMMA etching in acetone? Are there alternative methods or conditions (e.g., temperature, concentration, or other solvents) that could improve the etching process? Any suggestions or insights would be greatly appreciated.
Thank you!
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It depends on how you are transferring the material. If the material is CVD grown and you transferred it to the PMMA by etching the substrate then it will be difficult to remove the PMMA else it should easily wash in acetone.
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In the following paper;
considering
a) the experimentally verified two-way SOL = c to very high accuracy [1],[2],[3],[4]
finding the light times in a configuration of train and embankment with
b) the experimentally verified twin effect, to second order approx in v/c [6],[7],[8],
c) the Sagnac effect, verified to first order approximation in v/c [5]
the result is that the SOL in the embankment is L/c
while the SOL in the train is gamma*L/c, at variance with a)
Since a) must be complied, the Sagnac effect in longitudinal motion, an experimental evidence with a lower accuracy must be ameneded by assuming the Length contraction of the train as REAL.
THis means that Length contraction cannot be niether reciprocal nor symmetrical. That involves the existance of a preferred frame in which it is clear what is the non-accelerated system which moves more or moves less once the isotropy of SOL of one system is assumed considering what has been accelerated from where.
Out and back Speed of light
[1] Michelson, A. A., Pease, F. G., & Pearson, F. (1935). "Measurement of the Velocity of Light in a Partial Vacuum." Astrophysical Journal, 82, 26.
[2] Essen, L., & Gordon-Smith, A. C. (1948). "The Velocity of Propagation of Electromagnetic Waves Derived from the Resonant Frequencies of a Cylindrical Cavity Resonator." Proceedings of the Royal Society of London. Series A. Mathematical and Physical Sciences, 194(1038), 348-361.
[3] Evans, J., & Eisenhower, E. (1951). "An Interference Method for the Measurement of the Speed of Light." American Journal of Physics, 19(4), 356-359.
[4]. Hall, J. L., & Borde, C. J. (1976). "Measurement of the Speed of Light Using Laser Techniques." Applied Optics, 15(2), 300-304.
Test of Sagnac effect
Test of time dilation twin effect
[6] J. Bailey “Measurements of relativistic time dilatation for positive and negative muons in a circular orbit” Nature, 268-5618,pp. 301-305, (1977).
[7] D. Hasselkamp, E. Mondry, A. Scharmann, “Direct observation of the transversal Doppler-shift” A. Z Physik A, 289: 151, (1979).
[8] B. Botermann et al, “Test of Time Dilation Using Stored Li+ Ions as
Clocks at Relativistic Speed” Phys. Rev. Lett. 114, 239902 (2015).
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SQ: <<So I think it is the case to understand what are the conclusions of SR about the result of the proposed configuration.>>
Yes. Anybody interested has got the opportunity to read my former posts.
Eg. #9 on p. 461 [my first of July 3, 2024] within
proves reciprocity of time delay in SRT.
The scenario of the preprint is analysed in MANY OTHER of my posts.
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If we want to introduce a material similar to polymethyl methacrylate "with the characteristics mentioned in the next paragraph" that can be added to a precursor and create a composite, which organic or inorganic polymer is more suitable to have these properties?
*PMMA characteristics:
This material is one of the hardest and most solid polymers with
-higher transparency than glass and a polished,
-shiny surface and resistant to atmospheric factors.
-Polymethyl methacrylate plates have a significant resistance to atmospheric factors and sunlight.
-They have excellent optical properties and a transparent surface, and at the same time, they are more resistant to impact than glass.
-In addition, they have a very low moisture absorption percentage and good tensile and electrical resistance.
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When looking for an alternative to Polymethyl methacrylate (PMMA) with similar characteristics, the following organic and inorganic polymers can be considered:
Organic Polymers
  1. Polycarbonate (PC)Transparency: High transparency, similar to PMMA. Impact Resistance: Much higher impact resistance compared to PMMA, making it suitable for more demanding applications. Weather Resistance: Good resistance to atmospheric factors and UV radiation, though it can benefit from UV stabilizers. Optical Properties: Excellent optical clarity. Mechanical Properties: High tensile strength and good electrical insulating properties. Applications: Used in eyewear lenses, optical discs, automotive components, and protective barriers.
  2. Cyclo Olefin Polymer (COP) and Cyclo Olefin Copolymer (COC)Transparency: High transparency, often used in optical applications. Impact Resistance: Good impact resistance. Weather Resistance: Excellent resistance to moisture and UV light. Optical Properties: Superior optical properties, with low birefringence. Mechanical Properties: Good mechanical strength and rigidity. Applications: Used in medical devices, optical lenses, and packaging.
  3. Polyethylene Terephthalate Glycol (PETG)Transparency: High transparency, used in clear applications. Impact Resistance: Better impact resistance compared to PMMA. Weather Resistance: Good resistance to weathering, though not as resistant as PC. Optical Properties: Good optical clarity. Mechanical Properties: Moderate tensile strength and good electrical resistance. Applications: Used in packaging, signs, and medical devices.
Inorganic Polymers
  1. Silicone Polymers (Polysiloxanes)Transparency: Certain formulations are highly transparent. Impact Resistance: Good impact resistance, flexible. Weather Resistance: Excellent resistance to UV radiation and weathering. Optical Properties: Can have excellent optical clarity depending on the formulation. Mechanical Properties: High flexibility, good tensile strength, and electrical insulation properties. Applications: Used in optics, medical devices, and coatings.
  2. Polyvinyl Butyral (PVB)Transparency: High transparency, widely used in safety glass laminates. Impact Resistance: Excellent impact resistance, especially when laminated. Weather Resistance: Good resistance to moisture and weathering. Optical Properties: Good optical clarity, with use in laminated glass to provide shatterproof properties. Mechanical Properties: Good tensile strength and flexibility. Applications: Used in automotive windshields, architectural glass, and solar panels.
Summary
Polycarbonate (PC) is probably the closest alternative to PMMA due to its high transparency, excellent impact resistance, and good weatherability. For applications requiring very high optical clarity with low birefringence, Cyclo Olefin Copolymers (COC) could be considered. For flexibility and UV stability, Silicone Polymers are excellent alternatives.
Polycarbonate (PC) is widely used in industries requiring durability and clarity, making it a strong candidate for replacing PMMA in many applications.
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To prepare polymethyl methacrylate polymer for the study of acoustic properties, a mixture of methyl methacrylate monomer and benzoyl peroxide is used. This mixture is then heated and placed on a heater. To prevent the formation of bubbles during this process, what measures should be taken?
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Dear Sana Mohammadi, you are not following the proper way of a radical polymerization. The first remark is temperature should be controlled at a specific one. Putting directly your recipe on a heater will make temperature rise to higher values (formation of bubbles). A thermostated bath is the most used. First, you should purify your initiator (recrystallization), monomer (washing with concentrated alkaline solution or distillation to remove the inhibitor/stabilizer), purify solvent. Prior to addition of the initiator, O2 removing by inert gas (N2) stripping. If you don't have an experience with polymer synthesis, then take help of an expert in this matter form your vicinity. My Regards
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I have porous PMMA microparticles up to 1mm in diameter.
I would like to functionalise the surface with amines whilst keeping the particles intact.
Chat GTP has recommended ethanolamine or ATPES but I cannot find any articles that directly reference this. I am open to other methods too.
CuO nanoparticles are also present in the PMMA so I do not want to degrade those either.
Let me know if any thoughts or know of any papers for reference.
Thank you!
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MQ RBF use in this paper
Integrated diffusion term for 2nd order
compare the numerical and exact sol
1D heat eq
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sir check this code then error found in matrix A
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Greetings all
I have been facing a problem with Technovit 9100. The polymerization never worked with me I have tried multiple times with the (stable and destabilized) basis solution in different conditions, however, I still end up with a liquid form which never hardens.
Tissue type:
  1. Human acetabular bone with soft tissue attached. Total size: 13*10 mm.
  2. Human femoral head. Total size 5*5 mm.
Protocol:
1) Dehydration on tissue rocker for (agitation): (50%, 70%, 80%, 95%, 95%) 1 hour each; (abs alcohol) overnight then (abs alcohol) for 1 hour. At room temperature
2) Intermedium on tissue rocker for (agitation): Xylin for (1 hour) then again Xylin for (1 hour). At room temperature
3) Pre-infiltration solution; Solution preparation: 100 ml of basis solution + ½ g Hardener 1.
  • Solution used on tissue rocker for (agitation): 1 Hour At room temperature
4) Infiltration solution; Solution preparation: 100 ml of basis solution + 1.5g Hardener 1 + 10g of powder.
  • Solution used for 24 Hour At 4C
5) Polymerization: Solution preparation:
  • Stock A (100ml): 16g of powder + 80ml basis solution (mix until dissolve) + 0.8g Hardener 1 then top up the solution until 100 ml is reached.
  • Stock B (100ml): 0.8 ml Hardener 2 + 0.4 ml Regulator + 100 ml basis solution
Finally, the polymerization solution is used in a ratio of 9 parts from stock A + 1 part of stock B mixed immediately before use.
We have tried a number of conditions to see if the polymerization will happen:
  • Solution with the tissue at (RT, 4C and - 15C) for 24H
  • Solution with the tissue at (RT, 4C and - 15C) for 72H
  • Solution without the tissue at (RT, 4C and - 15C) for 24H
However, all of that ended unsuccessfully.
I would really appreciate any insight or help to this matter
Sincerely
Abdulaziz
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I would also increase your dehydration times. The polymerisation is inhibited by water as well as oxygen. For those sample sizes I think you would need several hours in each stage, if not more. Without good dehydration and infiltration you risk getting a block which is polymerised on the part around the sample but not inside the sample itself. Then the sample crumbles away when you try to cut the sections, and you are left with a plastic section with a whole in it where the sample was supposed to be.
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This is the method I am following adding 0.305 g of ammonium metavanadate (NH4VO3, Sigma-Aldrich, 99.99%), 0.119 g of sodium hydroxide (NaOH, Sigma-Aldrich, ≥97.0%, pellet), 0.205 mL of phosphoric acid (H3PO4, Sigma-Aldrich, 85 wt% in H2O) to 100 mL of 0.02 M aqueous citric acid solution (HOC(COOH)(CH2COOH)2, Sigma-Aldrich, ≥99.5%) while the solution was continuously stirred. Next, ammonium hydroxide (NH4OH, Aldrich, 28.0 ∼ 30.0% NH3 basis) was slowly added to the solution to adjust its pH to 9 at which metal ions can be chelated by citric acid. Then, water was evaporated at 80°C to transform the solution from sol to gel.
However, its not forming a gel even though water is evaporating, what should I do?
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I'm not familiar with the compound you are trying to make, but if the formula you've written is correct this is a trivalent vanadium (V(3+)) salt. I don't see in your procedure anything obvious that would reduce vanadate (V(5+)) to trivalent vanadium. Citrate is unlikely to do it, although it may reduce V(5+) to V(4+).
By the way, the concentrations seem low for gel formation - not impossible, but just an extra incentive to double-check that you got your procedure right.
Best regards,
Emanuel Cooper
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What is the optimal method to mix PMMA sheets with nano-powder?? the PMMA sheet 5cmx5cm
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I am doing EMSA using LightShift Chemiluminescent RNA EMSA Kit from Thermo Scientific. For the detection, I use stabilized Streptavidin-Horseradish Peroxidase Conjugate and Chemiluminescent Substrate (Luminol/Enhancer Sol and Stable Peroxide Sol).
I have been having this problem on and off, even though I perform the experiment with fixed protocol. I cann't figure out why sometimes I have black backgroud and white free-probe signal as shown in the picture.
By the way the bands shown in the picture is not the band we expected.
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How are you acquiring the picture? Is sounds like a problem with imaging settings.
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I have prepared naked silver nanoparticles by using sodium borohydride reductant. I have dried the sol in oven but the dried particles were like a dot on glass vial and yield was too low. I have also centrifuged the solution at 5000 rpm for 20 min but get nothing. Please guide, how can i get the powdered form for XRD and SEM.
I'll be very thankful in this regard.
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Ibrahim Akram BTW, in the presence of water or oxygen, you do not have 'bare' Ag (nano)particles. The surface (top 5 or 10 atomic layers) is fully oxidized and silver is in the Ag+ (monovalent) state and not as Ag0 (metal). ESCA/XPS easily shows this. And incidentally, it's Ag+ that's the bactericide not Ag metal. For more information, take a look at this webinar (free registration required):
Silver colloids and invisible ink
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Hello,
I would like to have coatings that can be applied to surfaces (metal, PMMA, or glass) to obtain a contact angle with water greater than 110°.
I'm looking for either coatings or materials.
Thank you very much
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Thank you :)
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May anyone tell me how to protect PMMA coating during TMAH etching? Is PMMA soluble in TMAH?
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Most welcome!
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Hello,
I'm trying to calculate the heat of reaction of this DSC of PMMA thermal decomposition but i'm not sure what this straight line means before the endothermic peak of decomposition. It looks like a bias accumulating an error between sample and reference. The material is PMMA dental resin and contains 1.0 % titanium dioxide and 5% of crosslinking agent Ethylene glycol dimethacrylathe (EGDMA).
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Dear Lucas,
that represents the energy consumed by heating up your sample. It reflects the heat capacity scaling with the temperature change. However, if your curve represents heating, it should be exo up because heating the sample consumes energy and appears as an endotherm in the DSC curve. That would make your degradation exothermic. See for instance here:
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To make a PMMA (Poly(methyl methacrylate)) coating superhydrophobic
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1. Try to functionalize surface of PMMA by using perfluoro compound.
2. Try to modify surface morphology of PMMA.
3. Mixing PMMA with another superhydrophobic material such as SiO2 midified perfluorosilane.
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Dear All,
I am trying to simulate a dimer and would like to restrain a part of it on both chains. not a problem and the error is commonşy reported. so i tried all teh suggestions but none is working as grompp is accepting one of the posres files but throws the error for the other one. my toplogy file looks like this.
---------------
; Include chain topologies
#include "topol_Protein_chain_A.itp"
;; Include CRD Position restraint file for Chain A
#ifdef POSRES_CRD_A
#include "posre_crd_chain_A.itp"
#endif
#include "topol_Protein_chain_B.itp"
; Include CRD Position restraint file for Chain B
#ifdef POSRES_CRD_B
#include "posre_crd_chain_B.itp"
#endif
#include "topol_Ion_chain_A2.itp"
#include "topol_Ion_chain_B2.itp"
#include "topol_Protein_chain_A3.itp"
#include "topol_Protein_chain_B3.itp"
; Include water topology
#include "./charmm36-jul2022.ff/spce.itp"
#ifdef POSRES_WATER
; Position restraint for each water oxygen
[ position_restraints ]
; i funct fcx fcy fcz
1 1 1000 1000 1000
#endif
; Include topology for ions
#include "./charmm36-jul2022.ff/ions.itp"
[ system ]
; Name
2 Protein in water
[ molecules ]
; Compound #mols
Protein_chain_A 1
Protein_chain_B 1
Ion_chain_A2 1
Ion_chain_B2 1
Protein_chain_A3 1
Protein_chain_B3 1
SOL 111424
NA 48
--------------------
any suggestions are appreciated.
thank you
ayesha
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Dear Ayaz
Thank you for your answer. I was able to resolve the issue with the help from answers on GROMACS forum. the problem was in preparing the position restraint files using the original pdb files and using their atom indices.
Thank you so much for taking time to read my question
Best
Ayesha
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In the cleaning process, I centrifuged the microsphere at high speed, but the product after centrifugation was plastic
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Hello, my curious researcher friend Yaru Yan! Let's dive into the intriguing world of PMMA microspheres and centrifugation.
PMMA (Polymethyl methacrylate) microspheres are fascinating materials, but they can behave unexpectedly during centrifugation. When you Yaru Yan centrifuge a solution containing PMMA microspheres, several factors come into play:
1. **Density Gradient**: During centrifugation, particles tend to separate based on their density. PMMA microspheres, being solid particles, have a higher density compared to the surrounding liquid (usually water or a solvent). This density difference leads them to migrate outwards, forming a concentrated pellet at the bottom of the centrifuge tube.
2. **Viscous Effects**: The viscosity of the liquid can affect the behavior of particles during centrifugation. As PMMA microspheres move through the liquid, they experience resistance due to the viscosity, which can influence their distribution.
3. **Forces on the Microspheres**: Centrifugation exerts centrifugal forces on particles, causing them to move towards the tube's bottom. As PMMA microspheres are relatively dense, they are driven more strongly towards the bottom of the tube.
The result of these combined effects is the formation of a concentrated pellet at the bottom, which can indeed appear somewhat "plastic-like." It's important to note that the appearance may depend on factors such as the size and concentration of the microspheres, the centrifugation speed, and the nature of the surrounding liquid.
If the product appears plastic-like after centrifugation, it might be due to the microspheres packing closely together in the pellet, giving it a solid, dense appearance. This behavior is typical for many solid particles during centrifugation.
If your research requires a different outcome, you Yaru Yan might consider adjusting the centrifugation conditions or exploring alternative methods for separating and cleaning the microspheres. Always remember that the behavior of particles in centrifugation can be influenced by various factors, and it's crucial to tailor your experimental conditions accordingly.
If you Yaru Yan have any more questions or need further insights, feel free to ask!
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Hi
I`m trying to synthesis zeolite catalyst and I need silica sol 25wt%
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Hello Mona,
You may buy it online. You may make an inquiry at Alfa Chemistry, they offer kinds of good-quality products.
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PMMA does not dissolve in water. I tried a lot to dissolve it, but the amount of polymer is reduced to milligrams.
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Dear Salman,
such solvent is THF that is currently used as eluent in SEC (GPC) chromatography or 1,4-dioxane which, however, is a bit dangerous due to easy formation of peroxides.
Ethanol as well as water are precipitators of PMMA.
Best regards, Jiri
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I have a photochromic organic compound not dissolving in anything except for hot toluene or DMF. I want to make a PMMA bulk material with my compound dispersed in a cube/sheet of PMMA as micro-nano crystals.
PMMA at 160 deg C (melting point) always lead to some coloration of PMMA itself. Alternatively, is it reasonable that I disperse the microcrystals in MMA monomer fluid, with some AIBN, then heat it up in a mold To get a photochromic cube?
Further, if the crystals are small enough, how small it should be to have transparent window?
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Hi,
in what form come your nanocrystals? If it is a solid powder, it's most likely aggregated, and you need to disperse it. I recommend ultrasonication with a high-energy probe. If it is already dispersed (check by DLS or other relevant technique), you may add it directly to the PMMA solution, but you won't make a mistake if you ultrasonicate it either. The final dispersion is controlled by a complex interaction between PMMA, your nanocrystals, and the solvent. To get a good dispersion, PMMA must adsorb on the nanocrystals in extended confirmation. The adsorption can be tuned by the solvent, concentration, and some other factors. You may use mixture solvents if you need to change the solvent parameters while keeping your nanocrystals soluble. The drying must be quick to prevent aggregation; then, it could be molded into sheets or cubes by standard thermoplastic means. We have a series of papers on this topic:
The coloration doesn't come from PMMA but from toluene. I would say use a different solvent, but that's tricky. However, you don't need to dissolve your nanocrystals beforehand; you may add it as powder and stabilize it sterically with the adsorbed PMMA if you manage to find the proper conditions.
The thermosetting approach could also be used if you don't mind that MMA is a volatile hazardous chemical and that a considerable amount of unreacted monomer is left behind unless you use frontal polymerization. The dispersion step with ultrasonication is pretty much the same as with the polymer solution.
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Hello everyone, I am currently using COMSOL to simulate the piezoelectric behavior of zinc oxide (ZnO) nanowires. I would like to add either PMMA or PDMS as the surrounding polymer material.
However, I have noticed that there are different types of PMMA and PDMS available. I would like to know the differences between them.
My second question is regarding the selection of PMMA and PDMS from the MEMS branch in COMSOL. COMSOL requires me to provide the coupling matrix, elastic matrix, and relative permittivity for these materials.Where can I find this information?
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Hi Hello everyone, I already know the reason. I need to correctly set the Domain of the piezoelectric material in comsol
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Hello,
I hope you are well,
would you please help me to find out how to remove the BPO initiator after the polymerization of PMMA? The polymerization method is suspension, and I need the final polymer shape as it is synthesized. I need a solvent that can resolve the BPO well and does not resolve PMMA.
Best regards,
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Acetone dissolves PMMA well and makes a film after dissolving.
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Dear researchers,
In many cases, the point where G'=G'' is known as gel point. Is that true? How can I check the gel or sol states using other methods?
(I often use the small amplitude oscillatory shear measurement against frequency to determine the cross point between the storage and loss moduli).
I am looking forward your advice
Thank you very much.
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Absolutely!
Also, remember that when a material is at gel-point temperature, the storage modulus, loss modulus, and tan delta don't change much with frequency. This is not the case for liquids and solids - meaning you can also use three plots showing how these three properties change with frequency to demonstrate you're in a gel-like state.
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Hello,
I hope you are doing well,
I'm looking for a retardant to decrease the polymerization rate in mixing PMMA and MMA with the BPO DMT initiation system. I can not change the initiation system. Please help me to select a good retardant for this system that I can add to solid PMMA.
Best regards,
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Dear all, your problem may be solved simply by reducing temperature or reducing (or even eliminate) DMT. My Regards
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Hi everyone,
To perform my analyses, I use an AIRTIGHT SPECIMEN HOLDER made of PMMA. This dome generates a low-angle peak (likely partially due to scattering) in my diffraction pattern and background noise that is difficult to correct, even by removing the main part of the peak. Therefore, I am looking to model this phase to improve the modeling of the analyzable phases.
There doesn't seem to be a suitable .CIF file available in COD.
What is the procedure for conducting refinement in these conditions? Should I treat these peaks as 'true diffraction peaks' or as scattered signals?
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Dear Gerhard martens,
Thank you for your response,
The analyses were conducted at a synchrotron facility with a wavelength of 0.729 angstroms. The diffraction pattern corresponds to an analysis zone where there are no samples present. Therefore, we can estimate that the only contribution obtained comes from the dome and the sample holder.
The attached diffraction patterns demonstrate the evolution of the diffraction patterns during the filiation process. The measurements were performed using an incident beam with a very small dimension of approximately 75µm x 125µm and an incidence angle of 7°.
I have changed the x-axis unit to make it independent of the wavelength.
I hope those clarifications make my problematics clearer. Thanks for your help.
Best regards,
JM.
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I'm interested in your previous experience with growing diatoms in plexiglass PBRs. I intend to use the photobioreactor for monospecific cultures/experiments with Skeletonema costatum. It has a diameter of approx. 150 mm, approx. 560 mm in height and a volume of 5 L.
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Through the use of potassium permanganate in limited concentrations, I have a researched this subject
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I need a basic CIF file of PMMA with their different crystalographic coordinates in the aim to modyfing it in Gaussian :)
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Not a CIF file, but you can build different types of PMMA using moltemplate. It contains an example for creating polyethylene which can be your starting point.
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I am conducting an experiment to measure the velocity of the axial swirler in the closed plexiglass chamber using LDV (TSI Ar-ion Innova 70C) in back-scattering mode, as shown in the picture, at a laser power of 1W. The probe axis is perpendicular to the chamber. A part of the beams is reflected by the plexiglass chamber into the probe, which causes the saturation of the photomultiplier tube. Also, I have a separate receiver for forward scatter mode, but it also faces problems due to the scattering of light from the walls. Please suggest the best way to acquire data.
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Could you rotate your plexiglass chamber on the few degrees away from normal orientation relatively incident beams? In such a way reflected beams from camera walls will be directed out of measurement volume.
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I need to make 2.5% formal sol
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675.7 uL of the 37% stock plus 9.32 mL of water.
This online calculator is really useful for these sort of calculations: Dilution Calculator - Molarity, Percent - PhysiologyWeb
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Dear researchers,
Excluding chloroform, which solvent would be suitable to dissolve PMMA while preserving its optical properties such as transparency, and which solvent would provide fast solvent removal? Could you provide a recommendation?
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Tetrahydrofurane works well as a solvent for PMMA. In our group we use it as a solvent in which we synthesize PMMA and also as an eluent in the size exclusion chromatography setup, which we use to determine the polymers' molecular weights and dispersities. The boiling point at 66°C makes a removal of the solvent quite easy, too.
Another solvent, which is even easier to remove might be dichloromethane, which has a boiling point slightly below 40°C.
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The colloidal photonic crystal thin film is made via self-assembly method of PMMA
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Thank you for your comprehensive explanation. It helped me a lot. Thank you again.
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Does PMMA with a low molecular weight may have a higher complex viscosity than PMMA with a high molecular weight? Why is this happening, and what causes it?
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Hi,
you must first consider how the molecular weight was measured, as suggested by Leonhard Kilian Doppelbauer. Nonetheless, there might be several reasons:
1. Viscosity is quite sensitive to very small (plasticizers) and very large molecules (thickeners).
2. Fillers, especially nanofillers
3. Branching
4. Tacticity
Isotactic PMMA has a Tg lower by 67 K than the syndiotactic stereoisomer. And viscosity scales with the relative distance from the Tg.
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I am preparing PMMA for triboelectric nanogenerator. Therefore, I would like to know how to prepare this solution for spin coating. The avg. MW is 120 000 and I have some solvents, such as Toluene, MEK or acetone, etc. The remaining problem is the solution concentration and stirring temperature/speed? Much appreciated.
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Hi i have the same question, were you able to get it to work?
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Is there any efficient methdology to make PMMA using MMA, AIBN and EGDMA ?
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Methyl acrylic acid (MAA) could be polymerized by standard free-radical polymerization techniques like other acrylic and methacrylic monomers. Mind the monomer purity, remove inhibitors and oxygen prior the reaction.
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Hi,
I would like to perform a computational study on PMMA dissolution in a solvent. I have to pay attention to the % PMMA dissolved with time. Also how this value changes depending on the shape of the PMMA sample. The whole system is stationary and no evaporation of the sample is allowed. I was wondering if I can simulate such as system using COMSOL? I searched for few such literature but no luck yet. Thanks.
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Ro Garcia F
We decided not to do a Comsol simulation on this. But, did some analytical analysis to compare with the experiments.
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I have been trying to resolve this issue for a long time now trying different strategies and still do not have a fix for this.
The problem:
I have a Si(p++)/SiO2 substrate with a 2D heterostructure consisting of hBN and TMDC. After exposure, I usually develop without a post-exposure baking step. I see cracks appearing only after the development process especially in resist where h-BN is under it. These cracks mostly appear starting from the edges of the pattern and propagate upto 50 microns in distance. I do not see any origin of cracks from the part where the resist is in direct contact with SiO2.
Things I have tried :
1. Different resist materials (PMMA, PMMA with copolymer EL11, ZEP520A). All resist have the same problem.
2. Using rounded corners in my pattern to avoid sharp features. The minimum feature size in my patterns is about 2 µm.
3. Post exposure bake.
4. I am already using low acceleration voltages of 10kV with 30µm aperture.
Can anyone help me with this?
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Great to hear that.
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I think oxidation is taking place due to high pH. How can I avoid this ?
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I would think the easiest way would be to prepare it under an inert gas such as nitrogen. Perhaps prepare an initial solution at neutrality, bubble N2 through for a few minutes to de gas the solution. Provide a N2 cover and then add your excess ammonia.
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The resulting film became brittle or two-phases.
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No thanks, please have a look at the following examples :
10.1007/s00289-010-0392-9
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Hello,
I am currently working on etching a 50nm diameter hole on 20nm SiO2. The ebeam exposure is done using 100nm of PMMA A2 as ebeam resist. What would be the etching time of the SiO2 in the best and worst selectivity of PMMA/SiO2 if anybody had the same experience?
Thanks,
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Thanks for your response Victor V Solovyev . We are using CHF3, CF4 gases.
I read that discussion. I will check that and share the updates if I got any response.
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Hi,
Can I use 37% formaldehyde (~10% methanol) to prepare 4% formaldehyde sol. in PBS for mice perfusion? How methanol can affect immunohistochemistry?
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Thanks a lot!
Best regards,
Alex
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I am currently developing a high hardness coating for PET and the problem now is that the coating can be very hard (pencil hardness 6H), but it is so brittle that it cracks easily when bent.
The main materials I use are urethane acrylate and nano silica sol, and The thickness of UV-cured coating is about 20um. Is there any way to maintain the hardness of the coating while increasing its flexibility ?
Can you give me some advices ?
thank you a lot !
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One way to increase the hardness of a coating without affecting its flexibility is to use a hybrid coating with two or more components. By combining harder and softer materials, it is possible to create a coating that is harder and more durable while still maintaining its flexibility. Additionally, solid-solution strengthening, nanostructure formation, and surface modification can also be used to improve the hardness and durability of coatings without sacrificing their flexibility.
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I am trying to achieve a tunable undercut profile by using bi-layer resist stack PMMA(Top)/PMMA-ZEP 2:1 Ratio(Bottom). I am pretty new to fabrication; hence, I am not sure how do I mix the PMMA and ZEP together?
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You could put your PMMA/ZEP 2:1 mixture in a beaker, and then you can use a magnetic agitator for say 5-10 min to homogenise your solution.
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As we know, PMMA is hydrophobic in nature. The synthesized PMMA has been made using MAA, EGDMA, TEOS, ethanol, and HCl.
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PMMA dissolves in chloroform, dichloromethane, acetone, cyclohexanone etc. But you included egdma - ethylene glycol dimethacrylate - which is a cross-linker. With enough cross links your material is insoluble - will only swell. The cut-off is often around 3% - so if you had more than 3% egdma you may not be able to dissolve. TEOS may cross link by exchange with the PMMA - or it may react with itself to generate silica materials.
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Hello, fellow scientists. Resently I have been experimenting on PMMA/Graphene composites. I have obtained a flexural strength of ~40MPa and a flexural modulus of ~2500MPa under the following conditions: 120°C, 50PSI, 1h air curing; obtaining bubble free Samples. I have been reading several papers that report higher flexural properties but I have no idea were I am making a mistake or missing details. I was thinking in adding some EGMMA as co-monomer. Is there any way to increase flexural properties without adding additives? Greetings!
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There are several strategies that can be used to increase the flexural strength of polymethyl methacrylate (PMMA), also known as acrylic or acrylic glass. Some options include:
  1. Increasing the crosslinking density: Crosslinking can increase the flexural strength of PMMA by creating a more interconnected network of polymer chains. This can be achieved through methods such as irradiation, heat treatment, or chemical crosslinking agents.
  2. Adding fillers or reinforcements: Adding reinforcing fillers or fibers to PMMA can increase its flexural strength by improving its stiffness and resistance to deformation. Options include glass fibers, carbon fibers, or ceramic particles.
  3. Increasing the molecular weight: Increasing the molecular weight of PMMA can also increase its flexural strength by improving its stiffness and resistance to deformation. This can be achieved through methods such as modifying the polymerization process or using high molecular weight monomers.
  4. Optimizing the processing conditions: The processing conditions used to manufacture PMMA can also influence its flexural strength. For example, controlling the cooling rate during the molding process or using a higher pressure injection molding process can improve the material's strength.
It is important to carefully consider the trade-offs associated with these strategies, as they can have different effects on other material properties, such as toughness, transparency, or processingability. It may be necessary to experiment with different approaches to find the optimal combination of properties for your specific application.
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How can determine the SOH( State of Health) and SOL( State of life) for Li-ion (NMC) EV- batteries? I want know about the BMS roles! Are these parameters expressed by percentage?
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Thanks alot
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Hi, I need to make an optical window 0.5 - 1mm thick and 6 mm in diameter from PMMA. I would really want to master the skill of production instead of buying some slug or film sheet because later would need to modify the shape ( make a wedge instead of a plane window ) and so on.
I am planning to make a mold using a 3d printed circular part ( see the drawing attached ) wedged between two microscope slides.
We gave it a try and made a sample, but at that time we didnt have the vacuum chamber and poured the pmma into the could mold. ( see the picture attached )
The problem is that the fist sample was quite large and separated from the glass rather easily, which is not the case for smaller sample. The second problem is bubbles.
Could you please suggest the exact step by step scheme to follow ( the concentration, temperature mode, time frames and so on ) to improve our results and obtain bubble free sample which can be safely parted from the mold after the hardening.
What I have:
1. Methyl methacrylate (CAS Number: 80-62-6) from sigmaaldrich
2. Azobisisobutyronitrile (CAS Number:78-67-1) from sigmaaldrich
3. magnetic stirrer hot plate, beakers, vacuum chamber, heating chamber
Thanks a lot in advance.
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Hello Georgy,
the first step is to produce a prepolymer with short chains of pmma. You have to figure out your iniator yield to get reproductive bubble free polymers. There are numerous literatur about these topic. At first glance I would recommend a smaller amount of AIBN for prepolymerisation and a thorough degassing of the slightly thickening batch (stirring, vacuum, cooling, ...).
With best regards
Carsten
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I want to partially remove the cladding of fiber OMPF1000. The core is made (PMMA) 980 microns, cladding of fluorinated polymer material 20 micron. I am not sure it has a jacket. I tried to remove using heating but the fiber bents on heating.
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Dear Vaishali Rawat, please have a look at the following similar RG thread and the attached files. My Regards
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Through TiO2 NPs synthesis by sol gel method, first I have sol and keep it on stirrer for several hours, after that, I always get white milky solution instead of gel, and I keep it on heat without stirring until all the solution evaporate, then I dry the white precipitate and get TiO2 powder. Is it wrong to have that and why do not I have gel?
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Hiba Kj The milky state shows that your particles in suspension are in the > 100 nm range (i.e. sub-micron) and larger. A true nano/colloidal suspension will be clear (may be colored) as I expect your sol-gel to be before firing. Reduce the concentration of the precursors (encourages smaller size), reduce the temperature and the time (minutes or seconds rather than hours - the chemistry should be quick) to retain your material in the clear state.
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Hi there,
I'm currently doing research on the compsition of the liquid phase generated by thermal degradation of Poly(methyl methacrylate) (PMMA).
In my group we are especally interested in finding the monomer methyl methacrylate (MMA).
But from literature I have kind of a clue what else I can expect to be in the mixture,
like methyl propionate, methyl isobutyrate and other carbonyl-, ester- and diester-compounds.
Their boiling points should range between 50 °C and 270 °C and I consider them themally stabel.
Now I thouhgt on first analyzing the samples with GC-MS, because the GC allows to seperate the different compunds and MS will help me to characterize those compounds.
The problem is, that I've never done GC-MS before and I'm a bit puzzled if I have to dissolve my sampels or if I can probe them directly?
Is there a benefit in using a solvent?
And what requiremnets should a solvent fullfil, apart form dissolving my sample and beeing thermally stable, especally regarding the boiling point?
Thanks already for your suggestions!
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Hello Christoph
You have already mentioned the most important criterion: all analytes should dissolve in the solvent without any problems. I think methanol would be a good choice. Since GC-MS systems usually have a high sensitivity, it makes sense to dilute the sample. You can determine the dilution factor yourself. I would prefer a split injection at this point, since residual monomers are mostly volatile and can therefore not be focused well at the column head. The split ratio can easily be adjusted to the concentration of the injection solution at this point (high concentration = high split ratio). The temperature program is column-dependent. Since I don't know which phase is installed in your GC, I can't say much about it, but optimizing a separation is not big a problem.
In my experience the mass range of the MS is optimal with 35-350 u, no residual air peaks are recorded and the high siloxane masses of the column bleed are also not recorded. Methanol as solvent has the advantage that it is also "invisible" with mass 32.
Otherwise, additional information would be useful, e.g. which instrument (manufacturer), which column, sample quantities, autosampler, etc.
If you have more questions I will look for helpful answers.
Good luck and many greetings from Krefeld
Joachim Horst
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Hi all,
I am finding polymer like PMMA and PC.
It should meet several conditions,
1. Transparent, high transmittance in visible light.
2. Tg is higher than room temperature.
3. Degree of crystallinity is very law.
I have found several qualified copolymer,
but I want to find a qualified polymer that has more simple structure.
Thank you very much.
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Dear Mason Lee, polystyrene meets all the requirements you mentionned. My Regards
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Hello,
I have PMMA polymer particles embedded with CuO nanoparticles.
I analysed two samples via ICP-MS and obtained the Cu wt% within the expected range.
I then analysed further samples via ICP-OES and have obtained Cu wt% that are far too low (like 1-2% when should be around 8-10 wt%).
I could visually see the increase in CuO across the samples so I know there was much more than what the results provided.
Does anyone have any suggestions as to why this would happen?
The samples were dry (around 8-20 mg provided) and contained only PMMA, CuO, PVA, NaHCO3, the lab then acid digested prior to analysis. The CuO completely dissolved and the PMMA formed a clump.
I have asked the lab to repeat the samples again on ICP-MS to see if this makes a difference though the lab did not seem hopeful that this would provide a different result as usually the error between the two techniques is less than 3%.
Thank you :)
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My first thought was: How close to the limit of detection is the Cu concentration in the ICP-OES sample? If the final volume of the sample diluted the sample too much, you will approach the lower limits of the instrument's accuracy. Roughly calculating; 10mg x 10% Cu in 10 ml final volume would be around 100 ppm. Even if it was 50 ml final volume, that would bring it down to 20 ppm, which shouldn't be a problem.
  • Could there be an interference from another element on your Cu wavelength? Maybe the sodium from the NaHCO3 is causing baseline issues?
  • Could the sample have absorbed moisture prior to analysis?
  • Might the clump of PMMA be preventing full dissolution of the Cu, physically holding the Cu inside? (I don't know what PMMA is.)
  • Are you sure the conditions were the same for the second digestion?
  • Have you double checked that the calculations and results from the ICP-MS analysis are correct? Maybe the ICP-OES results are good and you've missed something in the first analysis?
Maybe when you repeat the analysis, submit a dilute CuO solution as well and see if the two instruments give you similar results. If they differ, then you can investigate the instruments as the source of difference. If the same, then it was your preparation(s) of nano-particles that seems to be the problem.
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I am trying to spin coat single walled carbon nanotube (in DMF) and Gold nanoparticles (in Chloroform) on rough PMMA surface, but I am getting very non-uniform spread of the nanoparticles. There are random chunks/ islands of the nanoparticles after the solvent is evaporated. What are the possible reasons behind this phenomena? Thanks in advance.
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If the "particle islands" are regularly dispersed, what you observe should be due to the formation of individual drop of solvent during the drying. those drops can move the particles to there center while drying (see the "coffee ring effect"). In that case you need to increase the wetting of the substrate by your solvent i.e. increase the substrate surface energy. An O2 plasma treatment can help.
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I've been using an e-beam lithography recipe to fabricate 30 nm wide pattern (using JEOL JBX 6700 100keV system) followed by deposition of 2nm Cr/10nm Au struggle but I'm struggling to get rid of the side-walling even after using a bi-layer PMMA resist
My current bilayer recipe is
1. Spin PMMA 450k-A2 for 60 seconds @ 4000 RPMs
2. Heat on a hotplate for 5 minutes @ 180 C
3. Spin PMMA 950k-A2 for 60 seconds @ 4000 RPMs
4. Heat on a hotplate for 5 minutes @ 180 C
5. Expose resist using e-beam lithography (JEOL JBX 6700 100keV system)
6. Develop in cold 3:1 IPA:H2O for 40 seconds, 30 seconds in IPA, blow dry with N2
7. O2 ash (descum) for ~5 seconds
8. E-beam evaporate 2nm Cr/10nm Au (chamber pressure ~2E-08 torr)
9. Soak in hot acetone (60C) for 1 hour
10. Sonicate for 1 minute at very low power to remove residual metal
11. Rinse in IPA and blow-dry with N2
Even though the undercut in the bi-layer resist is supposed to passivate the sidewalling of the e-beam evaporated metal, for some reason, I'm still getting sidewalls as tall as 10nm.
Please help me in solving this issue.
Thanks!
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I think your e-gun evaporation is the culprit here, it is well known that radiation generated during the e beam evaporation might cause the cross-linking of the polymer. You may want to try thermal evaporation.
You may also want to keep the evaporation rate slow, to get a good idea of the real thickness of the deposited material.
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I am trying to fabricate some silicon pillars with different radiuses on SOI exploiting an Ebeam lithography with 30KV. I already tried different photoresists including PMMA, Ma-N, and SU8 to make a pattern on SOI but yet it didn't work properly. The issue is that the pillars are so close to each other (periodicity 190nm) that the backscattering is affecting other adjacent parts and the result is not good enough for the next step which is RIE etching. I was wondering to ask the experts how can I manage to make these features on such a scale using a different fabrication approach or photoresist...
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You can try the following things:
1) You can try to limit the no of electrons falling on the sample (current) by reducing the aperture size. This normally improves the resolution but at the cost of an increase in writing time.
2) Please make sure that your beam is focussed very well (as good as you can), this you can try by burning a spot in the unused area at higher magnification and then zooming out to see if you get a good circle and not oval in shape.
3) You can also try to decrease the thickness of the resist, it helps in writing smaller structure.
Please let me know if this is helpful.
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Normally, I make TiO2 sol with titanium isopropoxide, ethanol, distilled water and hydrochloric acid. But I don't know which chemicals how need use to for hydrophobic sol.
NOTE: I working on glass coating that's why solution must transparent.
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Also check please the following useful RG link:
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the PMMA is made by CNC
Does PMMA need silanization treatment, if so how to do it
i have Trimethylchlorosilane(TMCS), can this work?
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The surface of PMMA can be treated by radio-frequency (RF) discharge plasma in argon and subsequently grafted by vinylalkoxy silane to form a surface containing new polar functional groups. The decrease of surface energy of PMMA modified by plasma in the course of aging should be stabilized by silane grafting. The modification of PMMA in argon RF plasma with tetraethyl (methyl) silane is also suitable to use.
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Hello,
I would like to synthesize about 10g powder per batch of low molecular weight PMMA.
I have tried a bulk polymerisation using AIBN initiator, equal parts MMA and toluene, and Benzyl Mercaptan as a chain transfer agent, polymerising at 80-90dC for 30mins and then drop wise add in methanol but the dried polymer is not a powder and remains a sticky glue.
I am currently trying to increase AIBN and decrease BM amounts but doesnt seem to reach my desired qualities.
Does anyone have any ideas on how to adapt this method or is there a different method that may give better results?
Sigma adrich has this product https://www.sigmaaldrich.com/AU/en/product/aldrich/200336 which is basically what I want to produce (I will be adding other polymers in once I have sorted out the base recipe which is why I cannot just purchase).
Thank you.
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No thanks, if you decided on precipitation polymerization, then the best will be if it is done via one of the living/controlled polymerization techniques. Best of Luck in your work.
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I want articles about that and the ratio of zirconia
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Good day! As far as I can understand, incorporation of zirconia particles mostly increase the flexural strength of PMMA. While the concentration of zirconia influences PMMA, the type of acrylic resin, size, and silanization of zirconia particles do not influence the results. Thus, the addition of zirconia particles shows a positive effect on PMMA. Please, refer the following links:
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Dear all,
for unknown reasons the MF-319 developer attacked my thin film while I'm trying to do photolithography  using S1813 photoresist. but it seems that the damage reduced with reducing the developing time. Anyone know how can I reduce the developing time as much as possible?
Thanks in advance 
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Hello Omar, I can see that you had this issue few years ago... I am experiencing the same issue with oxide thin films. Could you finally reduce the damage?
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Hello, I’m looking for polystyrene/PMMA microsphere in Iran. Is there anyone to know where can I find them? Or could you please help me to synthesis them?
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Hi there,
I'm going to perform a behavioural experiment in a closed plexiglass chamber, linked to a ventilation system through a hole (let's think about it as a fume hood). In this experimental design I would like to record ultrasound vocalization (from 18kHZ) of an adult mouse, but I cannot put the microphone for detection (condenser microphone, 2 - 200 kHZ) inside the box.
If I keep it outside the plexiglass chamber, how much the signal of USVs will cross the plexiglass? Can I detect them without so much lost? Can the ventilation system affect the signal?
Thank you!
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The difference in acoustic impedance between air (~400 Rayls) and plexiglass (2.77 MRayls) will lead to very high reflection coefficients at the air/plexiglass and plexiglass/air interfaces, and therefore very low transmission coefficient, unless the plexiglass layer is extremely thin or the thickness is very close to 1/2 the wavelength in plexiglass (at 18 kHz, it is about 6.53cm, assuming 2350 m/s). For a 60 µm thick plexiglass layer the transmission coefficient would be around 0.1, and getting higher as thickness decreases. But that would not be very practical. If you target the 1/2 wavelength plexiglass thickness, note then that the transmission coefficient is going to be very narrow band (a couple of Hz), i.e. if you design the wall for 18 kHz, the transmission coefficient is going to drop very quickly as the frequency deviates from 18 kHz.
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During the addition of ions Na and Cl to the system in the sol, the program threw the error stating that "no line with molecule 'SOL' found in the [molecules] section of file 'topol.top'.
While the file topol.top has the entry in it. please suggest how to rectify the errror.
Thanks in advance.
Regards,
Vinay
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Hi,
If it still persists, just add a new line character around the line of SOL in topol.top file. Sometimes, gmx behaves in a weird manner during reading SOL.
HTH.
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I want to perform a protein-DNA-ligand complex simulation by gromacs. but my system contain two ligands named PTR and LIG. but when ever i am going to perform the energy minimization.
This is the content of the topology file:
;
; File 'Protein.top' was generated
; By user: arindam (1000)
; On host: localhost.localdomain
; At date: Mon Dec 24 16:49:35 2018
;
; This is a standalone topology file
;
; It was generated using program:
; pdb2gmx - VERSION 4.6.2
;
; Command line was:
; ./pdb2gmx -ff amber99sb -f duplex.pdb -o Protein2.pdb -p Protein.top -water tip3p -ignh
;
; Force field was read from the standard Gromacs share directory.
;
; Include forcefield parameters
#include "amber99sb.ff/forcefield.itp"
#include "PTR.itp"
#include "ligand.itp"
; Include chain topologies
#include "Protein_Protein_chain_A.itp"
#include "Protein_DNA_chain_B.itp"
#include "Protein_DNA_chain_C.itp"
#include "Protein_DNA_chain_D.itp"
; Include water topology
#include "amber99sb.ff/tip3p.itp"
#ifdef POSRES_WATER
; Position restraint for each water oxygen
[ position_restraints ]
; i funct fcx fcy fcz
1 1 1000 1000 1000
#endif
; Include topology for ions
#include "amber99sb.ff/ions.itp"
[ system ]
; Name
Grunge ROck MAChoS in water
[ molecules ]
; Compound #mols
Protein_chain_A 1
DNA_chain_B 1
DNA_chain_C 1
DNA_chain_D 1
PTR 1
LIG 1
SOL 46535
can anyone tell me the way out?
Best regards.
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Hello Sourav Pal
The directives in the .top and .itp files have rules about the order in which they can appear, and this error is seen when the order is violated. The include file mechanism cannot be used to  #include a file in just any old location, because they contain directives and these have to be properly placed.
In particular, "Invalid order for directive defaults" is a result of defaults being set in the topology or force field files in the inappropriate location; the [defaults] section can only appear once and must be the first directive in the topology.  The [defaults] directive is typically present in the force field file (forcefield.itp), and is added to the topology when you #include this file in the system topology.
If the directive in question is atomtypes (which is the most common source of this error) or any other bonded or nonbonded [*types] directive, typically the user is adding some non-standard species (ligand, solvent, etc) that introduces new atom types or parameters into the system. As indicated above, these new types and parameters must appear before any [moleculetype] directive. The force field has to be fully constructed before any molecules can be defined.
Hope it helps.
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I am trying to have a thin monolayer of gold nanoparticles on acrylic surface, but I don't find a suitable option for doing that. I tried thermal vapor deposition but that makes a continuous film, and the gold is no longer a thin film. Is there a way to electrochemically deposit gold nanoparticles on PMMA or any other method? Thanks.
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Noe Arjona Your suggestion is a good one, but it would need an intermediate conductive layer to connect to. One can buy ITO coated mylar and I've used this in the past to attempt to make plastic LCD's. I suspect that the end result would be a discontinuous film of Au and not the 'nanoparticles' as the questioner is requiring or requesting.
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I do Ti/Au e-beam deposition on bi layer PMMA and Az1505. there is bubble like deffect that is forming on the substrate. the starting pressure is around 2-4x10 -7 T and climb to 2x10 -6 T during deposition. I don't have temp reading. deposition rate is 4 A/s. i do 2x300 nm with a 15 min pause. what could be the source of the problem? i did a lot of that kind of deposition in the past with no problem. the only difference is that we change the cryopump in early january. any hint will be appreciate.
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Because secondary electrons are generated during the electron bombardment of the target, these secondary electrons and charged ions can damage PMMA during evaporation. An effective solution is to put a magnet above the target, which deflects the secondary electrons and ions in the magnetic field so that they can't bombard your sample. If you can't do it, try increasing the evaporating rate. Although the energy of the charged ions will be higher, there should be less secondary electrons generated because the coating time is reduced
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Hello,
I am trying to measure PMMA with a parallel plate rheometer, but I am having issues because as soon as I raise the temperature above the melting point, the polymer is immediately filled with tiny bubbles. This appears whether I start with the PMMA powder straight from the bottle, or if I use extruded or hot press pieces. Although the extruded and hot pressed PMMA looks 100% clear and free of bubbles before heating. As soon as the temperature rises, they become opaque and filled with bubbles instead of a clear, bubble free melt.
I thought maybe it could be water, as PMMA can be hygroscopic, but I let the PMMA sit in the oven at 80C for 3 days, and there was no difference. Bubbles still appeared at the higher temperatures
I am concerned since the bubbles cause inconsistent rheology data. Does Anyone here experience with PMMA in the rheometer and can share their best practices for sample preparation?
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Are you sure that the bubbles are gas bubbles as opposed to vacuum bubbles, see the following URL: https://www.ptonline.com/articles/injection-molding-how-to-get-rid-of-bubbles
Regards,
Thomas Cuff
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Hello,
I am making a W/O/W emulsion using (about 5w/v%) PMMA in DCM as oil phase. Have used either 0.1 to 1% PVA in the W2.
During solvent evaporation I have tried magnetic stirring in a in small bottle with 20mL water for W2 and also larger bottle with 200mL and have tried 200RPM (no central water spiral) to 500RPM (water spiral formed and noticed PMMA clump in the apex of the spiral).
The PMMA clumps together in one big clump or multiple clumps regardless of these settings.
Any other suggestions? Thanks.
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Just as a guess (no experiencia with your system), admitting that you succeded the first step(W/O emulsion) to achieve the second step (dispersing into water the W/O emulsion) you need a much better homogenizer. Maybe 3000 rpm with rotor/stator. And then stabilize emulsion with PVA (or other viscosity enhacer), as you tried.
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I want to know the lifetime of a titanium sol (TIO2).
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Thank you for your responses
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I tried some methods bu the solution starts aggregating after additio of acid
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There are various methods that can be used to synthesize TiO2 and the most commonly used methods include sol-gel process, chemical vapor deposition (CVD) and hydrothermal method among others. This review will focus on selected preparation methods of titanium dioxide photocatalyst
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WHAT IS THE ABALATION TEMPERATURE OF PMMA (ACRYLIC)?
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Dear Md AZHARUDDIN Ali, please check the following documents. My Regards
DOI: 10.5772/65637
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Hello
i am trying to extrude PMMA (powder, from SIGMA) using a twin screw extruder.
220C and 100rpm.
however, the material is coming out black (and also very slowly) pmma shouldn’t degrade until 350C and the extruder is clean (I passed other polymers through it and they did not come out black)
why is my pmma turning black? How can I avoid it?
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The Modelling of Extrusion Processes for Polymers—A Review Marko Hyvärinen *, Rowshni Jabeen and Timo Kärki Fiber Composite Laboratory, LUT University, P.O. Box 20, 53850 Lappeenranta, Finland; Jabeen.Rowshni@lut.fi (R.J.); timo.karki@lut.fi (T.K.) * Correspondence: marko.hyvarinen@lut.fi; Tel.: +358-40-590-8471 Received: 30 April 2020; Accepted: 4 June 2020; Published: 8 June 2020  Abstract: Extrusion processes are widely used in industries that aim to produce advanced solutions for increasingly sophisticated demands in the plastic, food, and pharmaceutical sectors. Though the process has been in use since the 1930s, limited information is available on the analytical computation of extrusion. Generally, production has been carried out based on empirical experience and trial-and-error approaches. The development of industrial operations is, however, best addressed by modelling the processes involved, and the flow of polymer melts and fibers in extruders has been subjected to some previous studies. Also included an overview of design of a die as well as challenges in sheet/film production. This article systematically and critically reviews the literature related to the process design, machine design, process parameters, flow models, and flow analysis of extrusion with a focus on modelling the extrusion of composite materials.
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The literature, of course, varies wildly. I was spinning 8% PMMA at 500 rpm for 1 min previously with pretty good results. I just got a new spin coater and now have much more control. Previous spin rates were based more on the fact that the spinner couldn’t handle glass slides at greater than 500 rpm. Now I can go up to 12,000 rpm (thanks Laurell).
So, I’m thinking 2000 rpm for 1 min with a 60C post bake should be good. Thoughts? Suggestions? For reference, I fabricate GFET biosensors. I’ve had excellent results with my current PMMArecipe but I think a thinner layer will leave me with cleaner graphene after annealing and fewer wrinkles.
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Dear Michael,
I have personally used PMMA950 in Anisol from Michrochem Inc.
Routine spin-coating conditions were: 3500RPM for 1 min, and then heating up 180C.
I have also noticed the double-PMMA spin-coating process - suggested by Ruoff et al. Nano Lett. 2009, 9, 12, 4359–4363) improves the quality of the obtained graphene layers.
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Varied forms of NP reinforcements are added to PMMA to improve properties. But each study uses multiple percentages of addition of the NP. Why is data from previously done studies not used as a base to select one percentage of addition in any of the articles? Why are always multiple percentages of addition being tested?
Can a study be done using a single percentage to test certain other property (selecting a single percentage with proven better result from previously done research)?
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Dear Pragati Kaurani, simply because there are various grades of PMMA and the same for NP's with different features. If you want to reproduce a previous study, then you should have exactly the same properties of raw materials, and respect also the preparation procedures. My Regards
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I can't seem to make the gel appear for some reason.
The procedures are:
1)Add abs ethanol and ttip solution and stir for 60 minutes (sol 1)
2)prepare a 1 ml NH4OH + 104 ml ethanol
3) add to it 23 ml of YEOS precursor and stir for 2 hours (sol 2)
4) prepare 5 ml 37% hcl + 150 ml distilled water
5) add that solution to "sol 1" and stir for 90 minutes @ 60 Celcius
This worked before the first time but the never seems to appear after i add water and hcl to the hydrolyzed ttip the first time
What am i doing wrong
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I want to make two step e-beam lithography process:
1) Expose and develop negative ma-N 2400 pattern firstly to make special relief, which should be embedded into the next layers.
2) Coat the sample with copolymer/PMMA bi-layer, expose it and remove the negative resist features through the open windows without affecting the copolymer/PMMA pattern.
I've learnt that ma-N 2400 can be removed also in strong base solutions, such as NaOH 4-10% (I have only KOH, maybe it is even better) - see http://nanolithography.gatech.edu/resists/processing_info_Micro_Resist.pdf - but I haven't checked yet that copolymer and PMMA will alive after that treatment.
Another issue could be partial dissolution (??) of the negative features in copolymer solvent (ethyl lactate).
I will be grateful for any advice and discussion!
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Is it possible to do double layer lift-off using ma-N 2400 series? something similar to LOR or bilayer PMMA?
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I have ~150nm PMMA coating Al2O3 (50nm) which I would like to etch ebeam fabricated patterns out of the Al2O3.
For UV litho patterns I use AZ 4533 and etch the Al2O3 with 80% H3PO4 at 110C. However, this etches through my PMMA as well.
I tried 5% H3PO4 (at 50C) for a gentler etch (needs 10+ minutes), but I can't tell if my PMMA will hold up to it.
Any thoughts?
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Hu & al. (Appl. Phys. Res. 2009, https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.651.6657&rep=rep1&type=pdf) have etched anodic aluminum oxide in 3% H3PO4 at room temperature, so it's possible that you could use milder conditions than what you have tried. You can also raise the pH of your 5% H3PO4 by adding a small amount of base (e.g. 0.1-0.3% NH3).
You can also try chelating agents, like HEDP (1-hydroxyethylidene-1,1-diphosphonic acid a.k.a. etidronic acid), citric acid, nitrilotriacetic acid...
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Hello everyone, I am trying to simulate the protein-ligand complex with Zn ion but during solvation i am getting the following error:
Fatal error:
Syntax error - File LIG.itp, line 7
Last line read:
'[ atomtypes ] '
Invalid order for directive atomtypes
I tried many ways but not able to solve this issue
My topology file
Topology file:
; Include forcefield parameters
#include "amber03.ff/forcefield.itp"
; Include chain topologies
#include "topol_Protein_chain_A.itp"
#include "topol_Ion_chain_A2.itp"
; Include ligand topology
#include "LIG.itp"
; Include water topology
#include "amber03.ff/tip3p.itp"
#ifdef POSRES_WATER
; Position restraint for each water oxygen
[ position_restraints ]
; i funct fcx fcy fcz
1 1 1000 1000 1000
#endif
; Include topology for ions
#include "amber03.ff/ions.itp"
[ system ]
; Name
Protein in water
[ molecules ]
; Compound #mols
Protein_chain_A 1
Ion_chain_A2 1
LIG 1
SOL 27420
I also placed ligand itp file below forcefield parameters but it doesn't work. If you guys have any idea how to tackle this problem please help me. Thank you.
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Hello,
I checked the topol.top where the forcefield parameters lines in top while in older version the force field parameters defines in last section of topol.top
so you have to define your ligand .itp in below forcefield parameters lines.
ex.
; This is a standalone topology file
;
; Created by:
; :-) GROMACS - gmx pdb2gmx, 2020.4 (-:
;
; Executable: /apps/GROMACS/2020.4/bin/gmx_mpi
; Data prefix: /apps/GROMACS/2020.4
; Working dir:
; Command line:
; gmx_mpi pdb2gmx -f protein.pdb -o complex.gro -ignh
; Force field was read from the standard GROMACS share directory.
;
; Include forcefield parameters
#include "charmm36-feb2021.ff/forcefield.itp"
#include "AW_GMX.itp"
.....
[ molecules ]
; Compound #mols
Protein_chain_A 1
LIG 1
SOL 13404
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Who caught explain, why the database of PMMA refractive index gets information for wavelengths more than 400 nm and there is no information for smaller wavelengths? This is hard to measure or there are no interests?
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I agree with both Michael Rüsing and Michel Stchakovsky . There has been some work on measuring the refractive index below 400nm for thin films, where their thickness allows measurements to be made: https://www.iasj.net/iasj/download/2006118a583cf11b
Surprisingly, the k values reported are low until <300nm.
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Dear all,
The reason I am trying to simulate the sheet, I want to add the graphene sheet as a substrate in a cubic box and evaporate some molecules on it. Unfortunately, I had a problem while trying to  run energy minimization using  (gmx grompp -f minim.mdp -c GRM_w.gro -p grm_w.top -o min1.tpr) I got the below error: Fatal error: number of coordinates in coordinate file (GRM_w.gro, 146535)              does not match topology (grm_w.top, 156815).
some differences between my simulation and the one in the website:
1. I am using gromos54a7 instead of charmm36. The reason for using gromos 54a7 that I will need to evaporate some molecules on the graphene sheet and they should be evaporated using gromos 54a7.
2. I am using GRM instead of GRA.The reason for using the GRM is that I found the graphene sheet.itp online for the gromos 54a7 and it was named GRM and hence, I had to name everything GRM to match the names in the .itp that I included.
The steps I did using the terminal on Linux :
1. cd and go to directory
2. create a text file named GRM.gro and paste the data belwo in the file:
GRM: 1 1 Rcc=1.420 Rhole=0.000 Center: Ring
4
1GRM C1 1 0.061 0.071 0.000
1GRM C2 2 0.184 0.142 0.000
1GRM C3 3 0.184 0.284 0.000
1GRM C4 4 0.061 0.355 0.000
0.245951 0.426000 0.284000
3. gmx genconf -f GRM.gro -o GRM_sheet.gro -nbox 15 10 1
create the graphene sheet
4. I created the file graphene.n2t and attached the below
C CG2R61 0.00 12.011 1 C 0.142 C CG2R61 0.00 12.011 2 C 0.142 C 0.142 C CG2R61 0.00 12.011 3 C 0.142 C 0.142 C 0.142
5. I created a new file named grm_w.top and included the forcefield, the water model spc and the graphene sheet.itp that I found it online.
; Include forcefield parameters
#include "/home/abdelaal/Desktop/GROMACS/C60-TAPC/GRAPHENE/gromos54a7.ff/forcefield.itp"
; Include topology for GRA
#include "/home/abdelaal/Desktop/GROMACS/C60-TAPC/GRAPHENE/GRM4x.itp"
; Include water topology
#include "/home/abdelaal/Desktop/GROMACS/C60-TAPC/GRAPHENE/gromos54a7.ff/spc.itp"
[ system ]
; Name
GRM in water
[ molecules ]
; Compound #mols
GRM 1
SOL 50
6. I chanegd the size of the sheet in the z direction using:
gmx editconf -f GRM_sheet.gro -o GRM_sheet_new.gro -box 10 15 10
7. I solvate the system using:
gmx solvate -cp GRM_sheet_new.gro -o GRM_w.gro -p grm_w.top
now the topology file grm_w.top was updated and a line was added as below:
; Include forcefield parameters
#include "/home/abdelaal/Desktop/GROMACS/C60-TAPC/GRAPHENE/gromos54a7.ff/forcefield.itp"
; Include topology for GRA
#include "/home/abdelaal/Desktop/GROMACS/C60-TAPC/GRAPHENE/GRM4x.itp"
; Include water topology
#include "/home/abdelaal/Desktop/GROMACS/C60-TAPC/GRAPHENE/gromos54a7.ff/spc.itp"
[ system ]
; Name
GRM in water
[ molecules ]
; Compound #mols
GRM 1
SOL 50
SOL 48595
now I have 2 SOL which I don’t know what should I do.
8. I included in my minim.mdp file a line with : Periodic_molecules = yes
9. I tried to run energy minimization using:
gmx grompp -f minim.mdp -c GRM_w.gro -p grm_w.top -o min1.tpr
and I got an error:
Fatal error:
number of coordinates in coordinate file (GRM_w.gro, 146535)
does not match topology (grm_w.top, 156815)
END of steps.
I read that if the difference between the 2 numbers is devisable by 3, it means that the problem in the solvate and you can change the number manually to match the other one. But it is not the case here. I also thought that the problem might be that I have 2 SOL lines in the .top and I removed the SOL 50 line but the difference decreased by 149 only.
Looking forward for your help, I have been trying for many days without success.
Attached are all the files I used it including steps file which contains all the steps I did as written above.
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Hi, saw this question pretty late. My suggestion would be to delete the initial line SOL 50. Now, either use a script, or simply a vmd to check the number of water molecules. Then finally update the number of water molecules. It should work fine now.
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Does anyone know a type of plexiglass that does not glare or reflect? I would like to build some mazes but I need plastic that doesn't glare because of video tracking.
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Dear Wendy Koss , you could make the plexiglass surface rough by grinding it but of course you will loss the transparency.
Alternatively you could use a plexiglass with an antireflective coating like those used in common glasses.
A quick search will bring lots of results, for example:
....
You could paint it as well.
Hope this helps. Good luck with your research and best wishes!
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e.g. A young male with features of chronic meningitis or multiple SOL (CSF and radiological features), but without any host risk factors and microbiological isolation of organism.
Should I treat this patients based on increased GM levels?
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Make sputum fungal culture and inform the Laboratory to check for Asperigellus. Generally It is a very rare cause of invasive infection in an immunocompetent host. Exclude non infectious causes. Better also to ask for PCR meningitis panel to exclude viral causes as well. A sample from SOL if possible for culture and cytology is the best to diagnose.
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Dear all,
In a coating project, I am trying to disperse PMMA micronized particles (around 1µm) in water.
However, because these particles are very hydrophobic, I have difficulties to obtain a stable and fine dispersion.
Moreover, even if the dispersion seems quite stable, when sprayed (with airless sprayer) the particles re-agglomerates during drying of the coating. This re-agglomeration phenomenon is not (or less) visible when the product is applied with a bar applicator.
I have already tried different ways to obtain a fine dispersion :
- thickening of water with clays or polysaccharides
- Addition of surfactant (I have tested SODIUM DIOCTYL SULFOSUCCINATE and Alkyl Polyglucoside)
- Addition of sequestring agent (Sodium Citrate) to prevent interaction of ions with the dispersion
Do you have any idea or know any protocol that could help me in that project ?
Thank you in advance.
Mathieu FIORE
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For better dispersion of PMMA particles in water
1.you can acidify the water and it will better hydrate the ether groups
2.Urea or guanidinium chloride salting agent can be used
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Polymer gets softened at glass-transition temperature (Tg), so the bonding of two polymeric layers is possible.
What are the operating procedures for thermally bonding PDMS to PMMA?
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The Flexdym polymer created by Eden Tech is a great alternative PDMS. It's biocompatible, transparent, gas permeable and can be molded in just a couple of minutes. And it binds to a variety of substrates including PMMA. Here's a link: https://eden-microfluidics.com/
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Polymers are generally damaged easily under high-voltage SEM due to low thermal conductivity. Although some papers are indicating that the accelerating voltage for PMMA can be as high as 20kV, I wanted to ask what is the maximum voltage that PMMA/GNP can tolerate.
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The best practical resolution in FE-SEM usually can be reached at accelerating voltage of about 1-3 kV. Higher voltage just increases the interaction volume via increasing the depth of electrons penetration into the sample surface and actually spoils the resolution. 20 or 30 kV is used for EDX or some "exotic" applications, e.g. to localize some contrast structures under a covering layer. It has no advantages in routine imaging.
Please read this discussion:
Good luck!
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Hi, I want to create a layer of PEGDA onto a U-shaped PMMA surface. The hyrogel formation works well however the PEGDA layer once set is moving within the PMMA wells as it is not bonded to the PMMA surface. Has anyone any suggestions tp promote bonding? It needs to be biocompaitble as there will be spheroids maintained in the PEGDA coated wells.
Thanks
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As far as I understand the question, it's clear to me that you need to stand on chemical approaches based on grafting concept to immobilize hydrogels on surfaces. The recent review by Mengjing Fu and et al., titled "Recent advances in hydrogel-based anti-infective coatings" is very helpful as you can request from the authors on the following RG link:
Best regards
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i have prepared PMMA polymer using PMMA beads mw 350000
using chloroform as solvent at 40 degree C. and poured in to glass petri- dish. And kept 24 hrs. for drying in room temperature. After drying, the film is not free standing and its not delaminating from the glass petri-dish. Plese help me to prepare PMMA polymer sheet.
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Dear Shruthi,
thanks for sharing this interesting technical problem with the RG community. Casting of PMMA fims using a solution in chloroform as a well-established method. My suggestion would be to make sure that your glass casting dishes are thoroughly cleaned and grease-free. A good cleaning procedure would be to soak them in ethanolic KOH solution (careful!, wear safety glasses!), rinse with dilute HCl and distilled water and then dry them in a oven at 120 °C. It might also be worth watching the "PMMA Thin Films Tutorial" on YouTube.
Good luck with your experiments!
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I am trying to determine whether PMMA dissolves in hexane.If it does dissolve in it, what are the parameters to dissolve PMMA in hexane?
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Dear Muhammad Dawood Jawad, complete overview on PMMA solubility in the following document. My Regards
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we usually use the PMMA to transfer monolayer MoS2 by CVD,but the acetone removing PMMA will damage the MoS2, while the MoS2 is covered in the porous substrate.So,could you help me solve the problem
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Important question, to encourage us to exchange, thank you
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Hi I'm working on cell scaffolds and l used Darcy and solid physics for modeling and I'm using Livelink COMSOL with MATLAB for material update (Young module) and I used the following code to set the previous solution as the initial solution .
model.sol('sol1').feature('v1').set('initmethod', 'sol'); model.sol('sol1').feature('v1').set('initsol', 'sol1');
But I got the following error: Messages:
The following feature has encountered a problem: - Feature: Time-Dependent Solver 1 (sol1/t1) Nonlinear solver did not converge
Maximum number of segregated iterations reached Time: 0 s. Last time step is not converged.
Thank you for your help.
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Assalamuwalaiqum Hani Soleimani
  1. Did you try keeping the two time dependent steps in the same study? I once tried having one study for a stationary step and another study for the time dependent step but that did not work, and when i brought them together it worked. Since you can specify which mesh to use for each study step, perhaps that could work for you.
  2. Or please go through the link attached herewith https://www.comsol.com/forum/thread/235292/how-to-use-previous-solution-as-a-initial-condition-in-time-dependent-pde-with-p
Hopefully this will help you jazakallah khairan.
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Dear All
I aim to design a microfluidic chip with a quite long channel with rectangle spiral structure and inside cells will not be seeded but instead, flowing for an extended period of time (1-2 days). Therefore, I need a large surface area to fit such structure. What is the maximum size I can achieve? Or basically is it the maximum surface area achievable with 4-inch wafer?
Thank you very much!
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Hello Su,
You're welcome. Good question. Choosing the material for your substrate depends on several factors, for example, equipment in your institute, minimum feature of the designed channels, required thickness, hydrophilicity or hydrophobicity of chemicals used in the drug testing....
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Hello,
Can someone with experience in CT image analysis help me to understand the elements of the pictures. It is a plate thermoformed from waste like ABS and PMMA polymers and fiberglass. I need to know what black dots represent, white particles, and also if fiberglass is visible.
Thank you!
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Dear Mihai, I can see that you are using our Software from Volume Graphics. The best would be to go through the training materials first and get an understanding of CT data. What you see is always the different absorption of X-Rays of different materials. The darker the "dots", the closer the absorptin is to the back groud material. In fact it can also be porosity of it is very similar. The "lighter" the dots are, the more absorption there is for X-Rays. It does not necessarily match the houndsfield scale at all, because industrial CT's do not get calibrated for medical purposes and then water is not having a houndsfield value of zero and air of 1000 what a doctor may expect. The grey values may reach to several thousands. If you can see fibers actually depends on the resulution you get from your setup. Check for the voxel size (properties of the dataset, rightclick in the scene tree). The voxel size needs to get very close to the fiber size, otherwise it won't show up as it cannot be resolved. Best get some infos from our support center. I think we can help with some basics in the physics and a training in the software.
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solution casting method.
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Dear Shruthi K N many thanks for posting this very interesting technical question. Blending of polymers with nanoparticles is certainly a hot research topic of significant current interest. In addition to the helpful advice given by Alan F Rawle please also have a look at the following relevant review article which might help you in your analysis. This review comprises 78 references to original research papers published in this field::
Recent Review on Poly-methyl methacrylate (PMMA)- Polystyrene (PS) Blend Doped with Nanoparticles For Modern Applications
Fortunately this review has been posted by the authors as public full text on RG, so that you can freely download it as pdf file.
Yet another potentially useful RG link is the following:
Fabrication of (Polymer Blend-magnesium Oxide) Nanoparticle and Studying their Optical Properties for Optoelectronic Applications
Good luck with your research and best wishes, Frank Edelmann
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If I put liquid paraffin wax between two aluminium plates or one aluminium plate and a plexiglass plate, and solidify it, will it create a strong bond? What kind of binding can occur between paraffin wax and aluminum or plexiglass? Does surface energy has anything to do with the adhesion? That's a lot of question. :p Thanks in advance.
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A firm connection with an adhesive is only possible if an adhesive material polymerizes after application (a chemical reaction transforms a monomer into a polymer). With a wax paraffin, polymerization is not possible, so it is not an adhesive. You can better compare paraffin with solder: when it melts, paraffin fills the gap and when it cools it solidifies and creates a connection. However, this connection is very weak because the strength of paraffin wax is very low. In addition, this connection will fall apart when it is reheated to the wax melting temperature (approx. 80°C).