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Pediatrics - Science topic

Pediatrics (or paediatrics) is the branch of medicine that deals with the medical care of infants, children, and adolescents.
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Through this question I would like to be aware of the role of the social worker in the pediatric area, specifically in oncology.
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Social workers in pediatric oncology provide emotional and psychological support to patients and families. They navigate the healthcare system, advocate for patient needs, and coordinate resources. Psychosocial assessments help tailor care plans to individual needs. Collaboration with multidisciplinary teams ensures comprehensive care. They also facilitate discharge planning and educate families on available resources.
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Hello,
I'm currently ib the process of uploading a case report in the cureus journal and I need to invite some peer reviewers alongside the reviewers assigned by the journal itself.
If anyone from the above mentioned specialities is interested in peer reviewing the article it would help alot, Thanks !
Sincerely,
Abdulla I. Abuhamaid, MBBCh
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Yes. I am a worker in the field of genetics. Presently doing on a project "molecular and genetic profiling of Tharu and Santhal tribes" sanctioned by Department of Science and Technology, Government of India, New Delhi. I am agree to review the papers of related (genetics) field. Thx
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Can anyone provide information or help me with a 4/5 year prognosis of Free-survival rate for
Pre b-cell all leukemia
2.5 yo
12%blasts
1500 wbc in diagnosis
Standard risk categorized
BFF protocol 2017 chemotherapy
Zeroed 14th day
No relapse at 4 years
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The 5-year free-survival rate for children with Pre-B-cell Acute Lymphoblastic Leukemia (ALL) is approximately 90%. This means that about 90% of children diagnosed with this type of leukemia are free of the disease five years after treatment. It's important to note that survival rates can vary based on several factors, including age at diagnosis, initial white blood cell count, and specific genetic features of the leukemia cells.
Prognostic Factors:
  1. Age: Younger patients generally have a better prognosis.
  2. Initial White Blood Cell (WBC) Count: A lower WBC count at diagnosis is associated with a better prognosis.
  3. Genetic Abnormalities: Certain genetic changes, such as hyperdiploidy (extra chromosomes) or the presence of the Philadelphia chromosome, can influence prognosis.
  4. Response to Treatment: How well the leukemia responds to initial treatment can be a strong indicator of long-term outcomes.
Treatment Options:
  1. Chemotherapy: The mainstay of treatment, typically involving multiple phases: induction, consolidation, intensification, and maintenance.
  2. Targeted Therapy: Drugs like imatinib for patients with the Philadelphia chromosome.
  3. Immunotherapy: Monoclonal antibodies or CAR T-cell therapy for certain patients.
  4. Central Nervous System (CNS) Prophylaxis: Treatment to prevent the spread of leukemia to the brain and spinal cord.
  5. Stem Cell Transplant: Considered for patients who do not respond to other treatments or have relapsed.
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What is acceptable plan of care for bilateral impalpable undescended testis ;pediatric age group.
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We have to measure the stretched penile length. If there is a small penis we should evaluate for DSD.If no, we should go for diagnostic laproscopy.
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Teaching postural control in pediatrics to college students
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Postural control in pediatric physical therapy is the ability of children to maintain balance and stability of the body, both at rest and in movement. It is essential for motor activities such as sitting, walking and moving. Physical therapists work on strengthening muscles, improving coordination, and developing sensory integration, especially in children with developmental delays or conditions such as cerebral palsy. The goal is to improve postural control to facilitate independence and participation in daily activities.
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Research gaps in pediatric heart failure management compared to adults can be significant due to the differences in pathophysiology, treatment responses, and long-term outcomes between children and adults.
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Here are several key research gaps in pediatric heart failure management:
  1. Etiology and Pathophysiology:There is a need for a deeper understanding of the diverse causes of heart failure in children, which can include congenital heart defects, myocarditis, and other conditions. Adult heart failure is often more related to ischemic heart disease and hypertension. Research on the unique mechanisms underlying pediatric heart failure is limited.
  2. Treatment Protocols:Current treatment guidelines for heart failure primarily derive from studies focused on adults. There is a lack of pediatric-specific protocols, making it challenging to determine the safest and most effective treatment courses for children.
  3. Pharmacokinetics and Pharmacodynamics:Pediatric patients metabolize drugs differently than adults, yet there is limited research on the pharmacokinetics and pharmacodynamics of heart failure medications in children. More studies are needed to establish appropriate dosing, effectiveness, and safety of existing and new medications.
  4. Mechanical Support Devices:Research on the use of pediatric-specific ventricular assist devices (VADs) and their long-term outcomes is limited. Many studies focus on adult devices, and pediatric applications can present unique challenges and complications.
  5. Transplantation:There are disparities in the understanding of heart transplantation in pediatric patients, including indications, timing, and post-transplant management. More research is needed to optimize candidacy criteria and to improve post-transplant outcomes in children.
  6. Long-term Management:Children with heart failure may transition to adulthood with chronic heart conditions. Research is needed to establish effective long-term management strategies, especially regarding the transition from pediatric to adult care.
  7. Impact of Comorbidities:The presence and management of comorbidities, such as obesity, developmental delays, and other chronic illnesses, in pediatric heart failure patients are not well-studied. Understanding how these factors interact is crucial for comprehensive care.
  8. Psychosocial Effects:The psychosocial impact of heart failure in children is often overlooked. Research is needed to explore the emotional, social, and psychological challenges faced by pediatric heart failure patients and their families, as well as the effectiveness of interventions aimed at improving their quality of life.
  9. Healthcare Disparities:There is a lack of research on access to care and health outcomes for pediatric heart failure patients from diverse socioeconomic and racial backgrounds. Understanding these disparities is crucial for improving care strategies.
  10. Innovative Therapies:
  • Research into novel therapies, including gene therapy, cell therapy, and stem cell treatments for children with heart failure, is limited compared to adult studies. Exploring these cutting-edge approaches could provide new avenues for treatment.
Addressing these research gaps is essential to improve the understanding, management, and outcomes of pediatric heart failure, ultimately leading to better care tailored specifically to the needs of children.
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I'm going to work on PB samples from pediatrics and I need to know the minimum amount of blood that I need to withdraw. How can I calculate it? And, I would be grateful if you can share your protocols and your feedback regarding this kit with me.
Thanks
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@Laharika Katamoni Thank you so much for your helpful answer. I started working and yes I found that 5 or 6 ml blood can be the least amount to draw in order to get around 100,000 or a little bit more Cd8 positive cells
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Pediatric supra condylar fractures sometimes show rotation after fixation. It may be significant in some cases. What is the normal range. What is significance of gordons classification.
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The acceptable amount of rotation in pediatric supracondylar fractures varies depending on the severity of the fracture and the age of the child. Generally, up to 10-15 degrees of rotational malalignment is considered acceptable in pediatric supracondylar fractures.
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As a (retired) paediatric radiologist I don't have large experience in paediatric gynaecology.
What I can say about neonates is this. To study the anatomy you may need contrast application via urethra or vagina. Be aware of the fact that the vagina in neonates is relatively large. The portio can be seen bulging inwards the vaginal wall. You can see the introitus to the uterus as well.
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Analisis de la demanda de atencion primaria
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Volver a la normalidad superando la pandemia nos abre los ojos para ver que el mundo está interconectado y que lo que hace cualquiera en otra parte puede influir en la salud de los demás. Los niños están muy expuestos a todos estos hechos y hay que cuidarlos con más atención que nunca. Gracias Alicia por tu Cuestión. Saludos.
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Hello,
Does anyone know if the CAD models for ICRP 143 Pediatric models are available for download? I have the MCNP voxel format but would like to get the CAD models.
Regards,
Kevin Capello
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read this you may find the solutions and try the help from icrp official help communit.
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For a better understanding of z-score calculations for undernutrition.
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In the context of malnourished pediatric patients, anthropometric measurements like weight-for-age, height-for-age, and weight-for-height are frequently employed. The WHO growth standards offer mean (M) and standard deviation (SD) values for weight, height, or weight-for-height in each age and sex group. The Z-score is calculated using the formula: Z = (X−M)/SD, where M represents the mean for the child's specific age and sex group. Z scores between -2 and +2 are considered normal.
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  1. I need a research project on pediatric ALL please help me
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You know there are some important factors we have to keep in our mild before planning a research proposal like rate / frequency of a disease, availability of investigation support, duration of study period and budget also. Like doing a RCT has a strong research value but requires time and fund on other hand doing observational ( acutely less to distinct as research) requires less supports for example : outcome and complications during indication phase or outcome of febrile neutropenia or act on other possible complications like frequency of hyperglycemia or coagulopathy or hyperglycemia or hypertension or nutritional status; even doing study on genetic records like pattern of cytogenetis or TPMT analysis in comparison of 6MP/ MTX dosing.
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What are the epigenetic drivers behind the formation and progression of pediatric brain tumors?
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Mostly genetic in origion
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Effects of online learning particularly in Pediatric PD
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Helpful for learning
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I am following two pediatric patients with epilepsy who are experiencing an increase in seizures after intranasal administration of exosomes. According to the research I have reviewed, exosomes are a very beneficial treatment option for intractable epilepsy and can restore lost brain functions. However, those articles did not mention anything about the effect of exosomes on seizures.
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I'm sorry, but as a Paediatric Radiologist this field doesn't fit into my expertise.
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To assess the gingival health in pediatric population, what indices are recommended?
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There are so many indices for gingival health assessment like Plaque index, gingival index and calculas indices
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i have atopic stating, work environment and employee performance on the pediatric oncology ward in Uganda
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Dear Maureen:
I think the idea is interesting and will contribute to our knowledge once developed. You should first make a general review of the existing literature on the subject, and then design a prospective study to validate the hypothesis. It would be interesting to investigate the existing tools to evaluate the work environment and the workers' subjective perception of it (validated questionnaires, etc...) and to define very well the control(s) group (another pediatric hospitalization service?). There are many relevant variables, such as the professional level (junior vs senior), the years dedicated to pediatric oncology, if the work is developed exclusively in that area or the care load. I encourage you with the project.
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How to improve intestinal preparation in children?
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Do enema to evacuate the complete faecal matter for better visualization of colon
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Since, OSA is considered highly important topic/issue for Pediatric or General Dental Practitioners particularly in context of its early diagnosis and timely management/referral to medical professionals. So, we should discuss here regarding the recent novel scientific evidence-based modalities/ways for the effective dental management along with inter-disciplinary approach and other aspects of such respiratory disorder.
The scientific discussion here from medical and dental professional globally in this regard would be utmost significant for increasing awareness in different health professionals and, furthermore to keep them updated.
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Okay
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Hi, Is there any general ambulation scale like the GMFCS that can be used with non CP pediatrics who have ambulation problems?
Thanks in advance
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Thank you for your help.
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1) Is the pediatric age group (<18) more or less susceptible to acquiring CoV-2 infection than other age groups?
2) Why does CoV-2 infection in the pediatric age group (<18) present as asymptomatic in nearly all cases?
3) Do asymptomatic children (<18 yrs) who are positive for CoV-2 by URT RNA test transmit the infection, and if so, is the route of transmission a respiratory route, or an oral route, or both?
4) Do asymptomatic children (<18 yrs) who are positive for CoV-2 by URT RNA test transmit the infection if their status is IgM+ IgG-, IgM+ IgG+, or both?
5) Is infection with CoV-2 acquired from a pediatric (<18) source always, rarely, or sometimes associated with COVID in adults?
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Removed. Thanks for your answers!
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based on the given information, it is possible that the patient is experiencing a form of paroxysmal nocturnal dyspnea (PND), which is characterized by sudden episodes of difficulty breathing at night. This condition is often associated with heart failure or other cardiac conditions. The bearhug-like rib pain may be related to the effort required to breathe during these episodes. The patient's technique of taking short-burst inhalations may have helped to increase oxygen saturation and alleviate his symptoms. However, it is important that the patient receives a medical evaluation to determine the underlying cause of his symptoms and to receive appropriate treatment.
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Can ChatGPT help the communication between parents of patients and pediatricians? Is there some fine-tuning version of ChatGPT with domain specific knowledge in pediatrics?
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Alicia Susana Cuevas Agree. And the academia is lacking large-scale corpus and benchmark collected from pediatricians. We don't know if ChatGPT has domain specific knowledge.
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Hello Researchers,
Is anyone in the gene therapy or pediatric research field looking for a reviewer? I am available and would be more than happy to help.
Thank you,
Sandra
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Ok, I am ready contribute in review of article
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Is cholecystectomy always recommended in pediatric patients with cystic fibrosis and asymptomatic cholelithiasis? Are there any cases in which a conservative treatment might be feasible? Bibliographic references are strongly encouraged.
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Gallbladder stones in children are usually treated conservatively, in cystic fibrosis general anesthesia propose a risk of chest infection which can be severe/fatal, so I wouldn't propose cholecystectomy unless pain is intractable or development of complications as pancreatitis
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Needs standard guidelines or scales or questionnaire's
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As tea, milk, soup.
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I would like to know more about indications, possible complications and long-term outcomes in patients treated with ASA. What dosage (mg/kg) is used? If someone could provide any references, that would also be great. Thank you!
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I have no personal expeience, but low dose acetylsalycil acid and propranolol treatmnets are frequelty used and both can be effective a proportion of patients.
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Hi everybody.. Do you think that type 1 DM can affect IQ of pediatric patients?
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Diabetic ketoacidosis (DKA) is linked to lower IQ scores in children with type 1 diabetes.
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I am interested in developing a survey to distribute among pediatric physicians, neurologists, teachers to collect data regarding the awareness of developmental coordination disorder in Israel. I would appreciate a "jumping-off" point via using a tool developed in other countries/cultures that I would then adapt to be suitable for the Israeli culture.
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Hi! These references might be of your interest
Hunt J, Zwicker JG, Godecke E, Raynor A. Awareness and knowledge of developmental coordination disorder: A survey of caregivers, teachers, allied health professionals and medical professionals in Australia. Child Care Health Dev 2021; 47 (2): [174–183]. Disponible en: https://doi.org/10.1111/cch.12824
Smith M, Banwell HA, Ward E, Williams CM. Determining the clinical knowledge and practice of Australian podiatrists on children with developmental coordination disorder: a cross-sectional survey. J Foot Ankle Res. 2019; 12 (42). Disponible en: https://doi.org/10.1186/s13047-019-0353-y
Gaines R, Missiuna C, Egan M, McLean J. Educational outreach and collaborative care enhances physician’s perceived knowledge about Developmental Coordination Disorder. BMC Health Serv Res. 2008; 8: [21]. Disponible en: https://doi.org/10.1186/1472-6963-8-21
Camden C, Rivard L, Pollock N, Missiuna C. Knowledge to practice in developmental coordination disorder: Impact of an evidence-based online module on physical therapists’ self-reported knowledge, skills, and practice. Phys Occup Ther Pediatr. 2015; 35 (2): [195–210]. Disponible en: https://doi.org/10.3109/01942638.2015.1012318
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Respected Researchers,
I am conducting a meta-analysis with respect to pediatric brain trauma, a population with limited literature. In an attempt to gather a large sample of patients, instead of sticking to one outcome measure, GOS/GOS-E, I am also including patients wherein other measures have been reported as well such as CAFAS, BRIEF, VMI etc.
Is it possible to relate all these outcome measures within a single meta-analysis with the sole purpose of identifying whether such patients have a good outcome or bad outcome? If so, can you please tell me the statistical methods required to do this?
Thank you very much to all.
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Dr. Alok Kumar Bharti , I was not aware of this. Thank you for your answer!
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With the increase in studies examining the effects of infant growth and/or diet on later onset obesity I would be interested to hear what areas clinicians think are missing in this growing area of research. If given the opportunity what area of infant diet and/or growth would clinicians examine in looking at later onset obesity?
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yes , in deed , infantile obesity is very difficult to manage especially those which attributed to genetic cause
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The KIDCOPE scales are widely used to measuring coping in children and adolescents. There is a lot of literature using them, or assessing them, but nowhere can I find the actual scales and information on scoring. I have managed from various sources to find the items in the child and adolescent scales, but while the adolescent scale seems to be scored on a 5 point likert scale the child one does not. All of these articles refer back to an article about the KIDCOPE's original development - Spirito A., Stark L. J., & Williams, C. (1988). Development of a brief checklist to assess coping in pediatric patients. Journal of Pediatric Psychology, 13, 555–574. http://dx.doi.org/10.1093/jpepsy/13.4.555. But nowhere can I find how the different versions were arrived at, responses, feeder/explanatory text etc.
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Please help with KIDCOPE TOOL please
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A 3- year-old female child whose growth rate has been in the lower 10th percentile over the last year presents with chronic, nonproductive cough and diarrhea with foul-smelling stools. She is diagnosed as having cystic fibrosis. For which of the following vitamins is this child most likely to be at risk of deficiency?
a) Vitamin C
b) Vitamin B6
c) Folic acid
d) Retinol (vitamin A)
e) Riboflavin (vitamin B2)
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All fat soluble vitamins are affected , they are vitamins (A,D,E, and K), so the answer is vitamin A.
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Hi,
Have researchers/clinicans highlighted a link between parotitis in children and COVID-19 ?
Thanks !
Thomas
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Please see the following attached document.
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for a project I want to create a 3D CAD model of the child's chest.
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google search
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I'm looking to measure the impact of an adjunctive therapy to traditional occupational therapy in an early education setting but am having difficulties in designing a project that factors in the high level of variability from one session to the next that naturally occurs in treatment.
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I suggest you search the standard tools in new articles in this area
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Sleep study is mandatory for adult patients with sleep apnea. Is it the same for pediatric patient with sleep apnea?
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Polysomnography can be used to perform accurate diagnosis regarding the presence and severity of apnea in children. However, the other aids mentioned above such as tonsil size, behaviour issues, noctural enuresis, etc. can help to screen the patients.
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finding special issues(Elsevier/SCI indexed) in the field of Pediatric field
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You can identify pediatric journals with the help of your linrarian & use their index to find special issues.
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Traditionally, pediatric surgeons leave a transanastomotic tube after esophageal atresia repair. However, there are several studies that have found that doing so increases the risk for anastomotic strictures, please check:
Lal DR, Gadepalli SK, Downard CD, et al. Challenging surgical dogma in the management of proximal esophageal atresia with distal tracheoesophageal fistula: Outcomes from the Midwest Pediatric Surgery Consortium. J Pediatr Surg. 2018;53:1267-72.
Alabbad SI, Ryckman J, Puligandla PS, et al. Use of transanastomotic feeding tubes during esophageal atresia repair. J Pediatr Surg. 2009;44:902-5.
Are there any studies out there that have looked at stricture rate with or without transanastomitic tubes?
Do you leave a tube? In which instances? With what rationale? Thanks!
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Using transanastomotic tube during esophageal atresia repair is a routine in our center, we can start early feeding via the tube
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Most pediatric surgeons advocate for routine acid suppression after repair of congenital esophageal atresia. However, there is conflicting data on this. Should proton pumps be prescribed routinely? For how long? What are the endpoints?
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I am working on assessment of the knowledge of my residents on the management of pediatric DKA. Are you aware of any similar studies that I could compare my findings with?
Thanks
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Pediatric endocrinology consultation
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Thank u dr wasna
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What about  the course of microalbuminuria (MA) in pediatric patients with SCN, is there any possibility of MA regression once developed?
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I'm not sure it will stop the decline, but it will reduce the evolution if we start hydroxicarbamide and enalapril -
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Sucking of thumb is a very common habit by the kids. Ultrasound scans have evidenced that thumb sucking can start as early as 15 weeks from conception. Why they start sucking even when they are in mothers' womb? Is it beneficial to them?
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This is an important issue.
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hola amigos, saben donde puedo conseguir el libro : MANUAL PRACTICO DE ATENCION PRIMARIA EN PEDIATRIA, AUTOR : HOSPITAL UNIVERSITARIO LA PAZ, JOSE GARCIA. Conocido como el libro naranja de la pediatría.
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sorry I haven't.
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Besides IP and IJP, which other indexed pediatric journals are there?
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indian journal of medical and paediatric oncology
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BCG vaccine is being seen as a new hope for COVID-19 patients. It can make our immune system to recognize and respond to a variety of infections, including viruses, bacteria and parasites etc (non-specific immune response).
There is only experimental evidence from both animal and human studies that the BCG vaccine has non-specific effects on the immune system. These effects have not been well characterized and their clinical relevance is unknown.
Also there is complete lack of evidence that the it will protect people against infection with COVID-19 . Two clinical trials addressing this question are underway, and WHO will evaluate the evidence when it is available.
In the absence of evidence, WHO does not recommend BCG vaccination for the prevention of COVID-19. WHO continues to recommend neonatal BCG vaccination in countries or settings with a high incidence of tuberculosis.
BCG also cannot be administered to anyone who has a compromised immune system, because it is a live-attenuated vaccine
The vaccine prevents infant deaths from a variety of causes, and sharply reduces the incidence of respiratory infections (not in COVID but in general). However, COVID-19 has not shown any major impact in pediatric age group in terms of morbidity and mortality , hence it might not be a useful tool, since the morbidity and mortality is higher in older age groups. At present I could not see any comprehensive data to support use of BCG vaccine for COVID-19 patients. What are your views on this?
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Dear all ,
I'm doing a pediatric study and the majority of sample's ages are repressented by year + months such as 6Y+4M. How can enter the data and calculate the mean in SPSS?
Thank you for your cooperation!
Kind regards,
Yazeed.
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Convert years to months. Average the ages in months. The average can be converted back to Yrs, months.
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In our centre, we are doing PPC even for older children upto 10-12 years of age and there seem to be no harm, rather beneficial and good outcomes. Please share your experiences.
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My practice is till 5 years of age, all the cases undergo primary posterior capsulotomy with anterior vitrectomy. After 5 years of age, for co-operative child, I do YAG capsulotomy at 6 weeks post op.
But when the follow-up is an issue, we should perform PPC with AV at the primary surgery itself in children.
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Most papers not giving in details about the disease in children. Any one have idea about it. Is Children are protected?
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I would like to ask the pediatric surgeons and urologists concerning circumcision in Caucasian children. What are the medical indications for performing circumcision in the neonatal period? What urological indications exist for this intervention in early childhood? What are the advantages and disadvantages of this manipulation, in case there are no other indications for it?
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When COVID19 pandemic started in China and until it reached USA, PMIS was unrecognized, we postulate in our article that this is related to ACE deletion/insertion polymorphism, read the article and let me know your answers and comments
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Covid19 seems to interfere with innate immune response inflammatory cascade. Therefore all diseases with a chronic inflammatory pattern especially with an increase of innate inflammatory cytokines such as IL 6 IL 8 MCP 1 IL1 alpha TNF alpha are prone to develop endothelial inflammation and precipitate in thrombosis and tissue destruction (interstitial pneumonitis). I would like to ask colleagues interested in innate inflammation if it would be useful the evaluation of inammatory cytokines to predict further complications if covid positive?
Thanks for discussion
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In your personal experience,How do you manage your life and make a balance between work, family and other related sections!?:)
I would be thrilled to have your points!
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Equally, dear Dr. Hossein
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Pediatric oncology patients specially leukemic children are admitted for a long time during Induction and other phases of treatment.
To do a qualitative study what tool can be used?
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The PedsQL modules for pediatric oncology were designed to measure health-related quality of life dimensions specifically tailored for pediatric patients with cancer.
You can examine this article:
Literature Review: Health-related Quality of Life Measurement in Pediatric Oncology: Hearing the Voices of the Children
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J Denyer has written much on this topic (with regard to EB patients). I am attaching a poster that may interest you as well.
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no.. i did nt..
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Pediatric patients' management requires natural closeness and facial expressions. But social (or physical) distancing and putting on masks and varieties of personal protective gear is a clear hindrance to the amiable and pacifying appearances. Children are likely to be experiencing worry, anxiety, and fear of observing these attires. What to do?
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In my workplace, radiology department in children's hospital, all staff wear a clear face visor with a Disney/cartoon character attached at the top (above your head) which is laminated and therefore wipeable with disinfectant. We have some masks with the clear panel over the mouth, used for people who lipread, these are also better for children to see your smile.
With a full covered face mask where staff have to use more eye expression it is actually a bit more exhausting keeping up the happy smiley face more !
We have in-house made cloth face masks (folded type) made in bright colourful material, given to patients and guardians (who can wear them) as they enter the hospital, so everyone has the same, they can bring their own face covering, of course.
It is a shame that most of our little toys have been removed from use (the big toys are constantly disinfected) and the usual nice things we have going on are currently on hold, eg: musicians, story tellers, magicians, balloon sculptors, visiting celebs etc
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We are performing an observational study on pediatric cases with COVID 19
Please for contact on my emails:
Whatsapp: +966599760661
Professor Khaled Saad
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We have a 500 bedded COVID hospital. Let me know any thing can done from my side. Odisha, INDIA
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how can we prepare in details tetracycline for topical injection in pediatric patient?
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Composition of Terramycin, containing Oxytetracycline is
Ampules10 ml Vial Multidose100 mg/2 ml250 mg/2 ml50 mg/ml 10 ml (5 β† 2 ml Doses)oxytetracycline50 mg125 mg50 mglidocaine2.0%2.0%2.0%magnesium chloride hexahydrate2.5%6.0%2.5%sodium formaldehyde sulfoxylate0.5%0.5%0.3%α-monothioglycerol
On the other hand,
this link shows TETRACYCLINE 3% MEANS 30mg in 1grm.
Therefore an Injection vial containing 50mg/ml , if half of its is added with 1 gram of petrolium gelly like Vaseline will make 2.5% tetracycline ointment.
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I am looking for possible subjects related to AAPM TG-158, that can lead to a M.Sc. or PH.D. degree.Specially in the measurement of neutron doses outside the treated volume ,, measurement of total doses to critical organs in pediatric patients, assessment of secondary cancer risks in pediatric patients.
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AAPM- American Association of Physics in Medicine.
You can find for free all their reports in their Website.
You can also be a member. I strongly recommend
Best regards
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Silver Diamine Fluoride is a boon to the pediatric dentist as it arrests an active carious lesion.
SDF is a 38% Silver Diamine fluoride in a colorless liquid with a pH of 10.
The Functional indicator of effectiveness (ie caries arrest) is when staining of dentinal surfaces is visible.
My query is to know the time required for the arrest of an active carious lesion after the application of SDF.
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Any relevant studies (RCT) reporting the same ?
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case report: pediatric 4 months old
multiple tumors in heart
refractory epilepsy since day one
multiple T2 lesions on brain
surgery of biggest one: parietal
histophatology: gangliocytoma
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Very rarely. It occurs more in other patologies associeted to m-TOR pathway disruption such as Cowden disesase.
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Children in rural settlements
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Children with urinary schistosomiasis can have a symptoms of haematuria (blood in urine). The fibrosis of the gallbladder and ureter are diagnosed in advance cases. Children with shistosomiasis can cause them to have anemia and stunting. Other clinical presentation and symptomatology includes in renal and urological involvement are dysuria, suprapubic dyscomfort, calcification, obstruction with consecutive ureteric and renal involvement (nephrotic syndrome [edema, proteinuria, arterial hypertension], megaureter, hydronephrosis, bacterial pyelonephritis, renal colic, membranoproliferative glomerulonephritis) Knopp, S et al, (2013) Diagnosis and treatment of schistosomiasis in children in the era of intensified control. For the diagnosis, according to WHO children with S. Haematobium almost always have microscopic blood in their urine which can easily be detected by reagent strips. School age children are at highest risk of infection with Schistosoma worms. The preventive measure to control the morbity among this age group is facilitated by chemotheraphy, often through the education sector. The treatment that is being administered to this is praziquantel it is an active drug against all human schistosomas species, this drug is widely use because it is safe, orally active, absorbs promptly and has a rapid onset of action. A dose pole has been developed for the treatment of children that is based on their height rather than weight (Knopp, S et al., 2013. Diagnosis and treatment of schistosomiasis in children in the era of intensified control).
References:
  • Knopp, S., Becker, S. L., Ingram, K. J., Keiser, J., & Utzinger, J. (2013). Diagnosis and treatment of schistosomiasis in children in the era of intensified control. Expert Review of Anti-Infective Therapy, 11(11), 1237–1258.
  • World Health Organization
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How can we bridge the gap and increase the tuberculosis detection rate in pediatric age group.
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In the paediatric age group, one needs a high index of suspicion. Here in the tropics, diagnosis is almost entirely based on clinical judgement as laboratory yields are low.
Clinical trials without evidence may breed drug resistance but has been the saving grace for some children in resource poor settings in which we practise.
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Particularly, what is the MRI and MRA role?
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The key criteria for confirmation of NCS were
acute narrowing of the LRV and large acceleration of blood flow at the
aortomesenteric portion with proximal distention on diagnostic imaging.
Computed tomography (CT) and doppler ultrasound (DUS) were performed to
make a comprehensive assessment of the angle between the AA and SMA,
LRV anteroposterior diameter ratio (hilar to aortomesenteric), and
hemodynamic characteristics.@
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hello, i need some help. i am searching for good reference values for pediatric laboratories for the potassium levels.
in the newest version of "Thomas" i found a good table, but they did not distinguish between serum and plasma. do you have an idea whether this is not done in pediatrics? please let me know, i would be very thankful
silke
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Hi Silke
It is known that potassium results from serum are 0.1 - 0.2 mmol/l higher than plasma results with differences of up to 0.9 mmoL.
Normal concentration of serum potassium at various ages in mmol / L (mEq / L):
Neonates 3.9 - 5.9 ; Lactants 4.0 - 5.3 ; Children 3.5 - 4.7 ; Adolescents and Adults 3.5- 5.1 Reference: Hyman D, Kplan NM, Tjhe difference between serum and plasma potassium. N. Engl. J. Med. 1985:313:642. And there is a Nomogram for Stimating Potasium Deficit in Plasma Levels, from ScribnerWashington University School of Medicine. 1960
Alteraciones Electroliticas en Pediatria by Luis Velasquez Jones 1991 Hosp. Inf. Mexico
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Severity Scoring tool used to determine initiation, Flows, Defined Ages (28 days and up) etc.
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Hey everyone, I was hoping to gain a better understanding of conducting a systematic review and more specifically whether a systematic review needs to separate adult and pediatric populations. For instance, if I were conducting a systematic review on the use music therapy for reducing anxiety in a post-surgical patient population, would I need to specify if it is an adult or pediatric population?
Can my systematic review contain both adult and pediatric populations in the final results?
Thank you in advance for your help!
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Dear Randell,
You sys review data depend on the research questions you try to answer. Check this out:
The Influence of Music on the Surgical Task Performance
  • 📷Michael El Boghdady
  • 📷Béatrice Marianne Ewalds-Kvist
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Do you use additional techniques when creating a stoma (stoma maturation) in pediatric tracheotomy ?
 Maturation suture
 Björk flap
 Starplasty
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We take prolene stay sutures after making incision over trachea,making sure not to take out rings of trachea and make it more collapsable.
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Which are the research groups or studies that explore the relationship between pediatric epilepsy and ketogenic diet? Thanks. 
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discuss the use of Vortex approach to airway management for:
  • obese patient
  • head injury patient
  • pregnant patient
  • pediatric patient
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It is important to note that the
failure of one device increases the possibility of failure of the next one, for example, in an obese patient with
positive predictors of difficulty for intubation, has a higher incidence of difficulty for ventilation
(including ventilation through a supraglottic device); likewise, percutaneous access to VA can be
very complicated.
Fortunately, we can exchange between these
access to the VA when one of them fails, being able to be
used interchangeably as a rescue for oxygenation
of the patient.
British Journal of Anaesthesia, 117 (S1): i20–i27 (2016) doi: 10.1093/bja/aew175
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This is the situation. A classification model with 5 groups with some kind of order has recently been published in adult patients under mechanical ventilation (http://bit.ly/33E3T2V) and I want to test if this classification also suits for pediatric patients in terms of similarity of proportions. I wonder if Chi2 (in a 2 x 5 table) vs. Cochran-Armitage test would be the best way to test this situation (I think the latter, because of the ordered classification) and also which would be the minimum sample size for each test. I found here (http://bit.ly/2OWB7Gz) that sample size in this scenario gets smaller when number of groups increases, and that with a five-group classification a n=400 would satisfy the requirements for a power near 80%.
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Yes, that was the paper I initially cited in the first question. With this, I can assume that a n=400 will provide 80% power and an alpha=0.05 as shown on table 4. Thank you for your invaluable advice.
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Dear fellow researchers,
Does anyone hold any useful information (or possibly a reasonable estimate) on the incidence rates (by age groups, if possible) of lactose intolerance and/or lactase deficiency in US?
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Please see the following RG link and PDF attachment.
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Dear all,
I am interested in books on healthcare architecture/buildings/design for my students for the MSc Healthcare Facilities.
Do you have any book titles to propose we should get for our library? Books could also be specialised, such as pediatrics, GPs, complex hospitals, older people etc.
Best regards,
Dr Evangelia (Lia) Chrysikou
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What is the effect of alpha blockers on kidney funtions in pediatrics ?
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https://uichildrens.org/health-library/continuous-infusions-picu-chart can be used to complement an observational trial on this Rx.
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If you have pediatric experience and looking for research collaborations, all done with ethical standards / IRB approval, you can post here and let us hope we can form a pediatric research core on RG.
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Welcome dr Hani.Temsah
What type of collaborative research you are looking for?
I have an important research about depression in secondary school students.
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Which are the vasoactives of choice according to the hemodynaimc alterations in pediatric septic shock ?
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I need detail explanation
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Ayele - You can get the best PhD dessertation tittle on the issues of nursing, public health, nutrition or health informatics, pediatric problems and so on by following certain steps: 1) Write down a list of topics that you are interested in and choose a topic that you are most interested in, 2) Narrow your topic to something manageable and talk to potential supervisors, friends, fellow scholars, colleagues etc, 3) Define the problem - a well defined problem is research half done and make your title concise, simple and clear, 4) Do a brief survey of literature to know how much work has already been done and what are the gaps in knowledge, 5) Choose a title which highlight the purpose of the study, which can often include its context, outcomes, and important aspects of the research strategy adopted.
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this investigation based on respiratory tract infection both upper and lower respiratory infection in pediatric patients
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Amit Kumar Shrivastava dear your question needs a bit explanation dear. I am also working in pediatric medicine, and there were hundred of patients belong to diagnosis of URTI or LRTI, but the region is too big, if you could point out some explanation. thanks
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Hello,
I'm working on developing an idea for a capstone involving prosthetics. My original idea had been a 3D printed sport-specific hand for pediatric patients with limb deficiencies, but since they are so adaptive, the need for it may be low.
I am hoping to stay in the area of pediatrics, and wondering if there are any suggestions on "literature gaps," unanswered questions, or simplistic devices/solutions needed.
Thank you for any suggestions!
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Following answers....
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It is documented in text books of pediatrics but not in procedures of the drug
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Although there are several off-label indications, it's approved for cystic fibrosis in kids.
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Recent research have confirmed that excessive fluid administration and positive net water balance has negative effects in critically ill children in certain conditions like acute lung injury or burned children. Fluid responsiveness tests may be used to identify fluid sensitive patients and limit unnecessary fluid administration in the hemodinamically unstable children , What do you thing about the performance of passive leg raising test in children. Do you use it in your daily practice in PICU? Effect of age or size? Any suggestions?
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You can also note changes in bedside ultrasound parameters such as IVC respiratory variability and LVOT flow variability when assessing a response to a PLR.
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By informing the physicians about the risks of radiation -induced cancer in patients undergoing the unnecessary radiology and CT scan examinations.
Awareness of the radiation -induced cancer values is essential for referring physicians, cardiologists and radiologists to justify the radiology and CT scan examinations.
The results of the following investigations showed that X-ray examinations are associated with non-negligible risk of exposure-induced cancer:
"Assessment of radiation risk to pediatric patients undergoing conventional X-ray examinations"
"Organ doses, Effective dose and Radiation risk assessment in pediatric radiography of the paranasal sinuses (Waters view)"
"Evaluation of radiation-induced cancer risk to patients undergoing intra-oral and panoramic dental radiographies using experimental measurements and Monte Carlo calculations"
"Estimating Risk of Exposure Induced Cancer Death in Patients Undergoing Computed Tomography Pulmonary Angiography "
"Assessment of Radiation-Induced Cancer Risk to Patients Undergoing Computed Tomography Angiography Scans"
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For x-ray radiation overexposures:
Though education among the health care providers about reducing the radiation exposure may help, this needs to be monitored with audit to ensure staff compliance with such policies.
One modality that may help in the future is the preset cropping of the radiation field to the required investigation, for example like chest x-ray, so that the AI-enabled X-ray machine will automatically reduce the patient exposure to the minimum.
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With MRI you can see the frequent comorbitity (or etiology !( of migraine and chronic ethmoidal, sphenoidal, frontal and maxillar sinusitis!
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This is logical and it is useful information
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I am looking for opinions of pediatric urologist about best approach and treatment of 3 months old boy with megaureter with hydronephroses grade 4 on left side. Right side with no problem.
First US taken 16 hours after birth:
Left kidney size 52mm
pelvis diameter: 12-14mm
calyces: 7-12mm
parenchyma: thinnest part 2mm
ureter: 8mm juxtavezical
VUR (5 days after birth): negative
MAG3: DRF: 34.8%
Second ultrasound (22.jan2019 at age 3 month and 5 days):
pelvis diameter: 14-19mm
calyces: 12-14mm
parenchyma: thinnest part 3mm
ureter: 14mm juxtavezical
Boy is on prophylaxy ATB. Would you recommend surgery and which method?
Many thanks,
MArtina Suchar Liptakova
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Regarding surgical aggression, I suppose if your only tool is a hammer, everything looks like a nail. Others have written works that confirm my experience with observing megaureters. (DiRento J Urol 190; 1021, 2013 Shukala J Urol 173; 1353, 2005). These and most current authors base clinical decisions on the result of the nuclear scan, but my experience suggests that the differential function of a kidney (determined by scan) changes little with or without surgery. Additionally the measurement of differential function itself is flawed. Many "obstructed" kidneys have greater differential function than the opposite normal kidney. (Liss J Ped Urol 9; 613, 2013). Jacobsen et al (J Urol 200; 440,2018) have conclusions that I don't agree with, but their work points out that the nuclear scintigraphy often does not change in concert with improved ultrasound appearance...which is worth noting in this case. In any event, I base my operative decisions not on the scan, but rather on the degree of sonographically determined hydronephrosis and, in general, the degree of hydronephrosis will generally improve with time. As the ureter is large, reimplanting it in a larger bladder is easier and therefore I generally wait to at least a year of age before making any surgical decisions. In this case, the scan was obtained too early, but it demonstrated that there was decreased function in the involved kidney. Enough so that I would not think that the contralateral kidney is sonographically "normal"...I would predict that it should be bigger than normal compensating a bit for the decreased function in the involved kidney. How big should a kidney be? Check out https//:wwwprevmed.sunysb.edu/jjc/MrNomogram/Default.aspx
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I want to no vitamin k1 formulation
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I think that would be a question best posed to a pharmacist with a CNSC (certified nutrition support consultant) via ASPEN (American Society of Parenteral and Enteral Nutrition). Vitamin K is a fat soluble nutrient and there are also 3 forms of Vitamin K. The intravenous dosage is not likely to be the same for an oral dose.
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Waiting to read this article after reading the excellent article 'Ventilating the newborn and child.
I am interested in any model of lung physiology that can help with studying modes of ventilation in newborns.
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Hi David
We have developed a volume-controlled prototype platform for neonatal resuscitation and ventilation to mitigate volutrauma and BPD.
Please see www.kmmedical.co.nz for overview and comparative studies.
We are interested to license.
Regards
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I am looking for the safest anti-emetic drug in children/pediatrics for my clinical assignment, I have searched but didn't get anything, please share the information.
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Uncommon (0.1% to 1%): Seizures, movement disorders/extrapyramidal reactions (oculogyric crisis/dystonic reactions, dyskinesia)
Rare (0.01% to 0.1%): Grand mal seizures
My 15 year experience in pediatric field not recognize as epileptiognic drug inducer
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I am a graduate student who is interested in general/helpful feedback related to use of this scale. I would like to use it in my research study. Thank you!
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Dear Heather Soistmann,
I have used The PedsQL™ Multidimensional Fatigue Scale (version self and proxy) in my Ph.D Thesis in Brazil, entitle: "Neuroimmunoendocrine trajectories and the response to stress and fatigue in pediatric cancer patients under chemotherapy submitted to clown intervention". I agree with Bomfim, with regarding the use of two versions of this instrument in order to obtained more data as well as more accuracy in your results.
Please, check out one of our recent open access publication in the journal "Integrative Cancer Therapies":
Regards,
Lopes-Júnior
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I injected the mice subcutaneously with 5 million human KNS42 pediatric glioblastomal cells (7mice), 5 million human KGN ovarian tumour granulosa cells (7mice) with matrigel. Tumours were not formed even after 3 months, but the animals became sick. So, we euthanised the mice and collected organs. Interestingly, we found that there was an enlarged tissue over the heart (could be thymus). But the tissue is negative for human ki67 marker. What it could be? Is it thymus lymphoma? Is there a possibility that mice randomly gets a lymphoma? I'm attaching the ppt to describe more in detail. Any suggestions are more than welcome.
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Using an immunodeficient mouse is critical for any kind of xenografting (see examples here: http://altogenlabs.com/xenograft-models/). The reason is pretty trivial - mice with a functioning immune system will kill off the transplanted cells. Even though an initial tumor might develop, it will be attacked by a present immune system, limiting the potential of any experiment. In your case, it seems like you did have a thymus, which could definitely have limited your results.
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We are looking at EGI system for clinical and possible research uses in Epilepsy Surgery Surgeries.
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sorry i can't help. i'm not a pediatric dietitian.
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I would like to discuss our results (fulfilled questionnaires (BDI, STAI, ADHD, Child Behavior tests) cca 6 years after pediatric heart surgery we have done statistics but I do think that our rejection had reason.
I am an anesthesiologist and intensivist and I feel not really gripped this topic.
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Thanks Phil I send you the other one in mail also
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I have a dataset where I want to assess and compare the performance of different mortality scores in burned pediatric population. For certain score, there is a probability of mortality. I want to test how accurate is the estimated probability (score calculated) with the actual observated event. For this Im using Stata where first I calculate the mortality score and then the probability (from 0 to 1) for each subject.
Q1. For the fitted model, Y= observed mortality, and X1=mortality probability estimated from score. Is this correct? or shoud I transform the probability into log(odds)?
Q2. To assess the utility of the score, I use the AUC ROC from the previous model with just one X variable. Is this correct? (c-statistic)
Q3. Does it make any sense tu try to estimate the calibration of the model, given I only have a summary of it (just the probability, not the model itself)?
Q4. If Q3 is affirmative, shoud I use AIC, BIC (other measure of fit) for the comparisson of the different scores or shoud I just compare the AUC ROC (roccomp)?
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Muchas gracias, proximamente haremos mas estudios de validación. Estare contactandola encaso de mayores dudas.
Muchos saludos desde Perú