Organic Chemicals - Science topic

El presente proyecto de investigación establece criterios generales para el diseño estático de “O-rings” en aplicaciones de configuración radial, usados en sistemas que confinan fluidos presurizados comunes en la industria Aeroespacial. Además de establecer los espacios de diseño en base a un diseño de Experimentos (DOE), y el uso de MINITAB en don...

Soil microbes are a major source of organic residues that accumulate as soil organic matter, the largest terrestrial reservoir of carbon on Earth. As such, there is growing interest in determining the microbial traits that drive soil organic matter formation and stabilization; however, whether certain microbial traits consistently predict soil orga...

Organic and inorganic chemicals co-occur in household dust, and these chemicals have been determined to have endocrine and metabolic disrupting effects. While there is increasing study of chemical mixtures, the effects of complex mixtures mimicking household dust and other environmental matrices have not been well studied and their potential metabo...

A novel 3D metal/semiconductor nanostructured surface‐enhanced Raman scattering (SERS)‐active substrate is constructed through Ag nanoparticles decoration of flower‐like ZnO nanorods (fZnOs) on a buckled substrate. A thermal treatment is applied to induce substrate buckling and is followed by ZnO hydrothermal synthesis and Ag reduction, resulting i...

Oleogels are semi-solid materials that consist primarily of liquid oil immobilized in a network of organized structural molecules, which provide stability and maintain the oil in the desired shape. Due to their structure, oleogels can stabilize large amounts of liquid, making them excellent carriers for active substances, both lipophilic and hydrop...

Coal is an important fossil energy source in the world, which provides important support for the development of industry. However, the chemical composition of coal is complex, and it may cause harm to the human body and environment during the process of mining and utilization, especially some aromatic hydrocarbons in coal that are strongly carcinog...

Oleogels are semi-solid systems that can function both as replacers of trans and saturated fats and/or as carriers of lipophilic bioactive compounds. However, bioactive compounds can affect the structure of the oleogel matrix and this effect depends on the properties of such compounds. Therefore, the aim of this study was to develop oleogels loaded...

Chronic stress is associated with anxiety and cognitive impairment. Repeated social defeat (RSD) in mice induces anxiety-like behavior driven by microglia and the recruitment of inflammatory monocytes to the brain. Nonetheless, it is unclear how microglia communicate with other cells to modulate the physiological and behavioral responses to stress....

The advent of dye-sensitized solar cells (DSSC) has expansively seen more studies as an alternative to silicon-based and thin-film solar cells due to their simple structure and relatively low production cost. In dye-sensitized solar cells, the dye is one of the major components for high power conversion efficiencies. The extracted dyes were charact...

This study aims to identify continuous water quality changes and identify fluorescence properties from urban rivers to marine zones. Various types of natural and anthropogenic sources derived dissolved organic matter (DOM) have been identified in this study. These include soil‐derived DOM, plant remnants, and soluble particles produced when organic...

This special issue in FEBS Open Bio was conceived to highlight some of the current research and future directions regarding research in the field of environmental toxicology of some organic pollutants, in relation to human health and disease. It has long been established that man has been exposed to many new (un‐natural) organic chemicals since the...

Introduction: Methemoglobinemia is a potentially life-threatening condition characterized by the reduced oxygen carrying capacity of hemoglobin. With the increasing popularity of natural and herbal biopesticides, there is a growing risk of exposure to substances that can induce this dyshemoglobinemia. This case report highlights the importance of r...

Background The probiotic potential of Lacticacid bacteria has been studied in various medical complications, from gastrointestinal diseases to antibiotic resistance infections recently. Moreover, diabetic ulcer (DU) is known as one of the most significant global healthcare concerns, which comprehensively impacts the quality of life for these patien...

Expired chemicals in chemical medicines represent a big problem in chemical medicines and we must find ways to treat expired medicines. It proposes a new technology for reuse instead of burying it with ordinary waste or instead of burning it in the ovens of the soil company., The side effects of an expired medicine (its chemical substances are o...

Ruzotolimod (Toll‐like receptor 7 (TLR7) agonist, RG7854) is an oral, small molecule immuno‐modulator activating the TLR 7 and is being evaluated in patients with CHB. As with other TLR7 agonists, the study drug‐related adverse events of flu‐like symptoms have been reported in some participants during phase I studies with ruzotolimod. An explorator...

Microorganisms consume and transform dissolved organic matter (DOM) into various forms. However, it remains unclear whether the ecological patterns and drivers of DOM chemodiversity are analogous to those of microbial communities. Here, a large-scale investigation is conducted along the Chinese coasts to resolve the intrinsic linkages among the com...

This study used computational techniques, including 3D enzyme structural modeling and molecular docking, to gain insight into the bioremediation of organic wastewater contaminants using E. coli esterase enzymes. Furthermore, a total of 24 wastewater organic chemicals belonging to different categories, such as pharmaceuticals, artificial sweeteners,...

The COVID-19 pandemic has led to the deaths of millions of people and severe global economic impacts. Small molecule therapeutics have played an important role in the fight against SARS-CoV-2, the virus responsible for COVID-19, but their efficacy has been limited in scope and availability, with many people unable to access their benefits, and bett...

This research aims to determine the organic chemical compounds of Moringa oleifera leaves using the GC-MS method. Execution of research at the Integrated Research and Testing Laboratory of Gadjah Mada University in Yogyakarta (LPPT-UGM). The study took place between April to June, 2024. Materials used were leaf extract M. oleifera L. varieties loca...

Oleogels are of high interest as promising substitutes for trans fats in foods. An emulsion-templated method was used to trap olive oil in the chitosan crosslinked with vanillin matrix. Oil in water emulsions (50:50 w/w) with different chitosan content (0.7 and 0.8% w/w) with a constant vanillin/chitosan ratio (1.3) were air-dried at different temp...

This study assessed the nutritional profile of camellia oil through its fatty acid composition, highlighting its high oleic acid content (81.4%), followed by linoleic (7.99%) and palmitic acids (7.74%), demonstrating its excellence as an edible oil source. The impact of beeswax (BW) and glycerol monolaurate (GML) on camellia oil oleogels was invest...

O presente trabalho teve como objetivo realizar a análise econômica do cultivo da palma forrageira, submetida a quatro tipos de adubação: química, química + orgânica, orgânica, e o tratamento testemunha, sem adubação. A análise consistiu de relações entre os custos e as receitas obtidas durante dois ciclos de avaliação, sendo consideradas duas form...

Fauna is highly abundant and diverse in soils worldwide, but surprisingly little is known about how it affects soil organic matter stabilization. Here, we review how the ecological strategies of a multitude of soil faunal taxa can affect the formation and persistence of labile (particulate organic matter, POM) and stabilized soil organic matter (mi...

Specialized chemicals are used for intensifying food production, including boosting meat and crop yields. Among the applied formulations, antibiotics and pesticides pose a severe threat to the natural balance of the ecosystem, as they either contribute to the development of multidrug resistance among pathogens or exhibit ecotoxic and mutagenic acti...

Adherence to the principles of green chemistry in a biorefinery setting ensures energy efficiency, reduces the consumption of materials, simplifies reactor design, and rationalizes the process parameters for synthesizing affordable organic chemicals of desired functional efficacy and ingrained sustainability. The green chemistry metrics facilitate...

This study aimed to enhance sludge dewatering through sequential bioleaching, employing the filamentous fungus Mucor sp. ZG-3 and the iron-oxidizing bacterium Acidithiobacillus ferrooxidans LX5. The mechanism by which Mucor sp. ZG-3 alleviates sludge dissolved organic matter (DOM) inhibition of A. ferrooxidans LX5 was investigated, and the optimal...

In this review, the principles of gas-phase proton basicity measurements and theoretical calculations are recalled as a reminder of how the basicity PA/GB scale, based on Brønsted–Lowry theory, was constructed in the gas-phase (PA—proton affinity and/or GB—gas-phase basicity in the enthalpy and Gibbs energy scale, respectively). The origins of exce...

Organic matter (OM) transformations in marine sediments play a crucial role in the global carbon cycle. However, secondary production and priming have been ignored in marine biogeochemistry. By incubating shelf sediments with various ¹³ C-labeled algal substrates for 400 days, we show that ~65% of the lipids and ~20% of the proteins were mineralize...

This poster presents a study investigating the presence of pesticides, pharmaceuticals, and personal care products in small water bodies using Polar Organic Chemical Integrative Samplers (POCIS) combined with non-target screening. The research aims to enhance understanding of the environmental impact of these contaminants by identifying a wide rang...

The coupling of excitons in π-conjugated molecules to high-frequency vibrational modes, particularly carbon–carbon stretch modes (1,000–1,600 cm⁻¹) has been thought to be unavoidable1,2. These high-frequency modes accelerate non-radiative losses and limit the performance of light-emitting diodes, fluorescent biomarkers and photovoltaic devices. Her...

BI 1358894, a novel small-molecule inhibitor of transient receptor potential canonical ion channels, is under development for treatment of major depressive disorder. Phase I trials assessing the safety and pharmacokinetics of BI 1358894 in Caucasian male healthy volunteers (HVs) have been performed. This Phase I, double-blind, placebo-controlled, p...

Background Colony stimulating factor 1 receptor (CSF1R) signaling is crucial for the maintenance and function of various myeloid subsets. CSF1R antagonism was previously shown to mitigate clinical severity in experimental autoimmune encephalomyelitis (EAE). The associated mechanisms are still not well delineated. Methods To assess the effect of CS...

Aromatic compounds are used in pharmaceutical, food, textile and other industries. Increased demand has sparked interest in exploring biotechnological approaches for their sustainable production as an alternative to chemical synthesis from petrochemicals or plant extraction. These aromatic products may be toxic to microorganisms, which complicates...

Sulphate‐reducing bacteria (SRB) are the main culprits of microbiologically influenced corrosion in water‐flooding petroleum reservoirs, but some sulphur‐oxidising bacteria (SOB) are stimulated when nitrate and oxygen are injected, which control the growth of SRB. This study aimed to determine the distributions of SRB and SOB communities in injecti...

To prepare a soft magnetic powder core, the magnetic powder surface has to be insulated by phosphating treatment. Organic chemicals such as ethanol and acetone are generally used as solvents for phosphoric acid, which may cause serious environmental problems. This work proposed deionized water as the environmentally friendly phosphating solvent for...

Se destaca la distribución, propiedades y secuencia temporal de la aplicación de vainas de algarrobo y semillas de cebil en diversas regiones andinas en términos de usos ritualizados. Un análisis desde la Circumpuna de Atacama (norte de Chile) proviene del templete formativo Tulán, datado a los 3050-2770 cal. AP. En el piso, se han excavado 27 enti...

Modelling approaches to estimate the bioaccumulation of organic chemicals by earthworms are important for improving the realism in risk assessment of chemicals. However, the applicability of existing models is uncertain, partly due to the lack of independent datasets to test them. This study therefore conducted a comprehensive literature review on...

Nanochitosan, derived from chitosan, offers a promising avenue for enhancing water quality through its remarkable properties in water treatment. Nanochitosan’s high surface area and adsorption capabilities effectively trap and remove various contaminants, including bacteria, viruses, heavy metals, organic compounds, and dyes from water sources. Thr...

Evaluating persistent trace organic chemicals (TOrCs) and transformation products (TPs) in membrane bioreactors (MBRs) is essential, given that MBRs are now widely implemented for wastewater treatment and water reuse. This research applied comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GC×GC/TOF-MS)-ba...

Helan Mountain is an important ecological safety barrier in northwest China. In this study, a heterogeneous site polluted by aniline on Helan Mountain was the research object, and the TMVOC (A Simulator For Multiple Volatile Organic Chemicals) model of aniline restoration by pumping was optimized by employing a column experiment. Four typical layer...

We investigated the metabolism and disposition of vornorexant, a novel dual orexin receptor antagonist, in rats and dogs, and clarified in vitro metabolite profiles in humans. Furthermore, we investigated the pharmacokinetics of active metabolites in rats and dogs and their CNS distribution in rats to elucidate its contribution to drug efficacy. [...

Autism spectrum disorder (ASD) is a behaviorally defined neurodevelopmental disorder characterized by deficits in language, communication, and social function with an estimated prevalence rate of between 1 in 30 and 44 U.S. births. Gene/environment (G × E) interactions are widely regarded as the most probable explanation for idiopathic ASD, especia...

The refluxing time is a significant consideration in synthetic study, because it could reflect the kinetics of the reaction process. Synthetic Organic Chemicals (SOCs) are man-made carbon-based compounds that are not likely to evaporate into the atmosphere and hence they could get into aquatic water bodies through terrestrial runoff or discharge fr...

Nanosensors work on the “Nano” scale. “Nano” is a unit of measurement around 10− 9 m. A nanosensor is a device capable of carrying data and information about the behavior and characteristics of particles at the nanoscale level to the macroscopic level. Nanosensors can be used to detect chemical or mechanical information such as the presence of chem...

Replacing crude oil as the primary industrial source of carbon‐based chemicals has become crucial for both environmental and resource sustainability reasons. In this scenario, wood arises as an excellent candidate, whilst depolymerization approaches have emerged as promising strategies to unlock the lignin potential as a resource in the production...

As an emerging contaminant, antibiotics have been widely detected in soil. In order to assess the environmental risk of antibiotics more scientifically, it is of great significance to study their bioavailability. In this study, oxytetracycline (OTC) and sulfamethoxazole (SMX) were selected as target pollutants, which were two typical antibiotics co...

Los hidrocarburos son compuestos químicos orgánicos que están formados exclusivamente de carbono e hidrógeno. Los principales hidrocarburos son los alcanos, los alquenos y los alquinos, entre otros. Y se encuentran formando cadenas carbonadas lineales, lineales ramificadas, cerradas y cerradas ramificadas.

Heterogeneous photocatalysts incorporating metal halide perovskites (MHPs) have garnered significant attention due to their remarkable attributes: strong visible-light absorption, tuneable band energy levels, rapid charge transfer, and defect tolerance. Additionally, the promising optical and electronic properties of MHP nanocrystals can be harness...

Following the advent of the coronavirus pandemic, tocilizumab has emerged as a potentially efficacious therapeutic intervention. The utilization of O3-Heterogeneous photocatalytic process (O3-HPCP) as a hybrid advanced oxidation technique has been employed for the degradation of pollutants. The present study employed a solvothermal technique for th...

An extensive analysis of the distribution patterns of three distinct classes of semi-volatile organic chemicals (SVOCs)—phthalates (PAEs), organophosphate flame retardants (OPFRs), and polycyclic aromatic hydrocarbons (PAHs) — across four discrete size fractions of dust (25, 50, 100, and 200 μm) was conducted. The dust samples were sourced from AC...

The World Health Organization Classification of Hematolymphoid Tumors (WHO) and the International Consensus Classification (ICC) of 2022 introduced major changes to the definition of CMML. To assess qualitative and quantitative implications for patient care, we started with 3,311 established CMML cases (according to WHO 2017 criteria) and included...

To assess the combined exposure of chemicals, it is necessary to comprehensively measure various chemicals in environmental media. The main instruments used to measure organic compounds are gas chromatography or liquid chromatography coupled with mass spectrometry. Selected reaction monitoring (SRM) measurements with triple quadrupole mass spectrom...

Background and Objectives: More than a billion people worldwide suffer from chronic periodontitis. The primary etiological factor of periodontal diseases is dental plaque and the bacteria it contains, particularly Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Prevotella intermedia, and Aggregatibacter actinomycetemcomitans. Z...

Electrochemical and impedimetric detection of nitrogen-containing organic compounds (NOCs) in blood, urine, sweat, and saliva is widely used in clinical diagnosis. NOC detection is used to identify illnesses such as chronic kidney disease (CKD), end-stage renal disease (ESRD), cardiovascular complications, diabetes, cancer, and others. In recent ye...

The air-blood partition coefficient (Kab) is extensively employed in human health risk assessment for chemical exposure. However, current Kab estimation approaches either require an extensive number of parameters or lack precision. In this study, we present two novel and parsimonious models to accurately estimate Kab values for individual neutral o...

Guadua angustifolia produces phenolic compounds, and this production may be influenced by the application of chemical, organic, and biological fertilizers. Currently, the effect of such fertilizers on the synthesis dynamics of this group of metabolites in bamboo is unknown. In this study, the total phenolic content (TPC) and total flavonoid content...

Plants have been used for centuries to decorate homes and add a touch of nature to interiors. Beyond their aesthetic appeal, plants have numerous benefits for indoor environments. Research has shown that plants can purify the air, improve indoor air quality and have psychological and physiological benefits. In this research, it aims to figure out t...

The manuscript demonstrate which percentage indexes of fibrous and organic material are necessary in composting windrows, the replacement of the biocatalyst (feces) by organic sludge, with the purpose of forming an alternative quality fertilizer. Individual windrows were designed with different compositions based on 10 calculations of different pro...

It was well documented that macro/trace elements were associated with the neurodevelopment. We aimed to investigate the relationship between copper (Cu)/zinc (Zn)/iron/calcium (Ca)/magnesium (Mg) levels and cerebral palsy (CP) by performing a meta-analysis. We searched the PubMed, Embase, Cochrane and Chinese WanFang databases from January 1985 to...

Citation: Ballinas-Indilí, R.; Nicolás-Vázquez, M.I.; Martínez, J.; Ramírez-Apan, M.T.; Álvarez-Toledano, C.; Toscano, A.; Hernández-Rodríguez, M.; Mera Jiménez, E.; Miranda Ruvalcaba, R. Synthesis, Cytotoxic Activity and In Silico Study of Novel Dihydropyridine Carboxylic Acids Derivatives. Int. J. Mol. Sci. 2023, 24, 15414. https://doi. Abstract:...

Disposal of significant tonnages of rice straw is expensive, but using it to mobilise phosphorus (P) from inorganically fixed pools in the soil may add value. This study was carried out to determine whether the use of rice straw mixed with phosphorus-solubilizing microbes could solubilize a sizable portion fixed soil P and affect P transformation,...

There are a variety of methods employed by laboratories for quantifying extracellular vesicles isolated from bacteria. As a result, the ability to compare results across published studies can lead to questions regarding the suitability of methods and buffers for accurately quantifying these vesicles. Within the literature, there are several common...

Introduction: Biological risks are a major global problem in the workplace. The recentCOVID-19 pandemic has highlighted the need for a more comprehensive understanding of thebiological risks at work. This study presents data on both communicable infectious biologicalagents and non-communicable factors leading to death and disability for the year 20...

Periodontitis is the chronic inflammation of tooth-supporting tissues that leads to loss of tooth support if untreated. Conventional therapy for periodontitis (mechanical removal of microbial biofilm and oral hygiene enforcement) is augmented by anti-microbial and anti-inflammatory drugs. These drugs are frequently delivered locally into the period...