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Ophthalmology - Science topic

Eye Disease Management and Oculoplasty
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Publications related to Ophthalmology (10,000)
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Article
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Purpose In patients with diabetes, unrecognised hypertension is a serious problem risk factor for the development and progression of chronic complications. The study aimed to determine the prevalence of masked hypertension in normotensive diabetic patients, the factors affecting it, and its association with diabetes complications using ambulatory b...
Article
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Background Birdshot retinochoroiditis (BRC) is a rare and chronic bilateral uveitis mostly found in Caucasians. As few data are available about the clinical course of BRC in Hispanic patients, we aimed to report the clinical findings and the evolution of BRC in Brazilian patients. Methods This retrospective cohort multicenter nationwide study was...
Article
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Background Central retinal artery occlusion (CRAO) is a neuro-ophthalmological emergency whose optimal management is still under debate and due to the absence of definite guidelines, practice is expected to vary. We aimed to characterize early evaluation as well as acute treatment and diagnostic approaches in German hospitals with a stroke unit (SU...
Article
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Tertiary outpatient ophthalmology clinics are high-risk environments for COVID-19 transmission, especially retina clinics, where regular follow-up is needed for elderly patients with multiple comorbidities. Intravitreal injection therapy (IVT) for chronic macular diseases, is one of the most common procedures performed, associated with a significan...
Article
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Background To determine the repeatability and agreement using corneal tomography of a swept-source optical coherence tomographer (SS-OCT) compared to a rotating Scheimpflug camera (RSC) in normal eyes and keratoconus (KC) eyes. Methods This prospective repeatability analysis was performed at the Department of Ophthalmology of University Hospital C...
Article
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Background Dry eye disease (DED) is a common disease in ophthalmology, affecting millions of people worldwide. Recent studies have shown that inflammation is the core mechanism of DED. IL-20 is a proinflammatory cytokine involved in various inflammatory diseases. Therefore, we aimed to explore the role of this cytokine in the pathogenesis of DED an...
Article
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Background To evaluate the efficacy of retinal photography obtained by undergraduate students using a smartphone-based device in screening and early diagnosing diabetic retinopathy (DR) . Methods We carried out an open prospective study with ninety-nine diabetic patients (194 eyes), who were submitted to an ophthalmological examination in which un...
Article
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Optical coherence tomography (OCT) is a three-dimensional optical imaging technique, frequently (but not exclusively) used for retinal imaging, that was first reported in the early 1990s. Since this time the technological development of OCT has been strongly influenced by its potential as a medical imaging technique. The first clinical prototype fo...
Article
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Nicht nur national, sondern auch vor allem international muss der Augenheilkunde und den Ophthalmologen in der Ukraine besondere Aufmerksamkeit geschenkt werden: In den letzten Jahren entwickelte sich in der Ukraine eine exzellente, hochmoderne augenärztliche Ausbildungskultur auf höchstem Niveau, die sich an internationalen Ausbildungsaktivitäten...
Article
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Key messages: Applications of bioinformatics and artificial intelligence (AI) to analyze biofluids in ophthalmological diseases are increasingly popular. However, their application in retinal vein occlusions (RVO) is not known. We highlighted that bioinformatic analyses using metabolomics and proteomics, and to a lesser extent AI-based analyses h...
Article
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Background Microsurgery is a growing field which requires significant precision and skill. Eyesi Surgical, which is usually introduced during residency or fellowship, is an ophthalmologic microsurgery simulator which allows users to practice abstract microsurgical skills and more specialized skills. The purpose of this study was to assess the inclu...
Article
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After going into the etymology of the word “optotype”, this article covers some tasks in ancient times that required good visual acuity (VA). Around 300 BCE, Euclid formulated the existence of a visual cone with a minimal visual angle at its tip. Trials to test VA appeared AD 1754. Around that time, texts were introduced by opticians in order to be...
Preprint
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Diabetes Mellitus (DM) can lead to significant microvasculature disruptions that eventually causes diabetic retinopathy (DR), or complications in the eye due to diabetes. If left unchecked, this disease can increase over time and eventually cause complete vision loss. The general method to detect such optical developments is through examining the v...
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Background Corneal topography is a clinically validated examination method for keratoconus. However, there is no clear guideline regarding patient selection for corneal topography. We developed and validated a novel artificial intelligence (AI) model to identify patients who would benefit from corneal topography based on basic ophthalmologic examin...
Article
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Aim To investigate vascular density (VD) changes in the superficial (SCP) and deep capillary plexus (DCP), radial peripapillar capillary plexus (RPCP), Foveal avascular zone (FAZ) and thickness changes of peripapillary retinal nerve fiber layer (ppRNFL) and choroid (CT) using optical coherence tomography angiography (OCTA) ipsilateral eyes of patie...
Article
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Background Posterior lamellar keratoplasty and especially Descemet membrane endothelial keratoplasty (DMEK) are gaining interest worldwide. Little is known about the influence of donor factors on DMEK outcome. Here we provide an overview of the existing peer-reviewed literature on this topic and present the design of the upcoming cooperation study...
Article
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Purpose To study the regression patterns of subretinal fluid (SRF) in central serous chorioretinopathy (CSCR) on sequential en face optical coherence tomography (OCT) and its relationship to leak locations. Methods Retrospective study on patients with acute CSCR. Inclusion criteria were (i) availability of data, sequential OCT and OCT angiography...
Article
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Innovations in Ophthalmology Holographic elysium of a 4D ophthalmic anatomical and pathological metaverse with extended reality/mixed reality Extended reality is one of the leading cutting-edge technologies, which has not yet fully set foot into the field of ophthalmology. The use of extended reality technology especially in ophthalmic education an...
Article
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Purpose We describe a portable practice model for acquisition of microsurgical skills using widely available inexpensive tools and materials as a model in learning ophthalmic corneal suturing skills. Methods Interested participants without prior microsurgery experience affiliated with the Jacobs School of Medicine and Biomedical Sciences with no p...
Preprint
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Neural networks have been rapidly expanding in recent years, with novel strategies and applications. However, challenges such as interpretability, explainability, robustness, safety, trust, and sensibility remain unsolved in neural network technologies, despite the fact that they will unavoidably be addressed for critical applications. Attempts hav...
Article
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To evaluate the surgical outcomes and complications of evisceration or enucleation with primary implantation, performed by ophthalmology resident trainees, in regards to patients with recalcitrant endophthalmitis or panophthalmitis. We also compared the surgical outcomes and complications between resident trainees and experienced staff. In this ret...
Article
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This study investigated the reliability and correlation of two contrast sensitivity test (CST) devices in young adults with normal visual acuity, with or without refractive surgery. 57 patients aged 20–39 years who received both manual (OPTEC-6500) and automated CST (CGT-2000) examinations from June 19 to July 24, 2021 were retrospectively enrolled...
Book
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Foster Kennedy syndrome (FKS) is characterized by visual loss due to compressive optic atrophy in one eye and papilledema in the contralateral eye brought on by increased intracranial pressure. The underlying cause of this ophthalmologic condition is the presence of an intracranial space-occupying lesion that compresses the ipsilateral optic nerve,...
Book
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Visual evoked potentials (VEPs) represent a valid electrophysiological tool in neurological pathologies. VEPs are the expression of the electrical activity of the visual pathways up to the optic nerve to the calcarine cortex. These potentials provide a non-invasive exploration method of the functionality of the human visual system through detecting...
Chapter
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Foster Kennedy syndrome (FKS) is characterized by visual loss due to compressive optic atrophy in one eye and papilledema in the contralateral eye brought on by increased intracranial pressure. The underlying cause of this ophthalmologic condition is the presence of an intracranial space-occupying lesion that compresses the ipsilateral optic nerve,...
Article
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Purpose Coronary bypass surgery is emphasized in aetiology of ischemic optic neuropathy. Our aim in this study was to investigate the pattern visual evoked potentials (PVEP) in patients before and after coronary bypass surgery. Methods Thirty-one patients were included in the study. After a full ophthalmological evaluation, PVEP was assesed in the...
Article
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Purpose To determine the prevalence and risk factors for pterygium in geographically diverse regions of India. Methods A population-based, cross-sectional multicentric study was conducted in adults aged ≥40 years in plains, hilly and coastal regions of India. All participants underwent a detailed questionnaire-based assessment for sun exposure, us...
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Purpose To assess which cases should be assorted exclusively to high-volume surgeons and identify when should a cataract surgeon seek assistance from a senior colleague. Methods The medical records of 2853 patients with age-related cataract were reviewed. Preoperative risk factors were documented for each case, and they were divided into surgeons...
Article
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Purpose To evaluate the limbal ischemia objectively in ocular surface chemical injuries by using anterior segment optical coherence tomography angiography (AS-OCTA). Methods In this cross-sectional study, acute ocular surface chemical injury patients with less than 1 week injury history were enrolled. Demographic data of the patients were noted, a...
Article
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To determine the prevalence of allergic sensitization in patients with vernal keratoconjunctivitis (VKC) and to provide an overview of published studies on this topic. We systematically searched 11 literature databases on 24 May 2021, for studies with cross-sectional data on the prevalence of positive allergy tests in patients with VKC. Our main ou...
Article
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Ophthalmology is the branch of medicine it deals with eye and its problems. Expert System contains the knowledge about particular diseases. Machine doctor is one without any human doctor machine can cure ophthalmology problems by using expert system. Our machine doctor provides both advice about diseases and the information about diseases by using...
Article
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Glaucoma is considered as the main source of irrevocable loss of vision. The earlier diagnosis of glaucoma is essential to provide earlier treatment and to reduce vision loss. The fundus images are transfigured in the ophthalmology and are used to visualize the structures of the optic disc. However, accuracy is considered as a major constraint. To...
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Background Persistent hyperplastic primary vitreous (PHPV) in a patient with tuberous sclerosis (TS) has been described in one previous case report in 1999. Otherwise, there is no literature around this potential association. We describe a case of an infant with TS and PHPV. Case presentation An 11-month old male was under investigation for leukoc...
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Harlequin syndrome (HS) is a rare autonomic disorder. The causes and risk factors of the disease are not fully understood. Some cases of HS are associated with traumatic injuries, tumors, or vascular impairments of the head. Symptoms of HS can also occur in some autoimmune disorders, ophthalmic disorders, sleep disorders, and with certain organic l...
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Purpose: This cross-sectional study aims to evaluate the actual prevalence of telemedicine, with a particular attention to teleophthalmology programs, in the Piedmont region of Northern Italy and investigate the prospects of the discipline, comparing the situation with the rest of Italy. Information about the current teleophthalmological developme...
Article
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Purpose: To summarize the existing treatment options regarding central retinal artery occlusion (CRAO), branch retinal artery occlusion (BRAO), arteritic anterior ischemic optic neuropathy (AAION), non-arteritic anterior ischemic optic neuropathy (NAION), and ocular ischemic syndrome (OIS), proposing an approach to manage and treat these patients....
Article
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Australia has one of the lowest per capita numbers of ophthalmologists among OECD countries, and they predominantly practise in metropolitan centres of the country. Increasing the size and distribution of the ophthalmology workforce is of critical importance. The objective of this review was to investigate the context of rural ophthalmology trainin...
Article
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Background With the rise of artificial intelligence (AI) in ophthalmology, the need to define its diagnostic accuracy is increasingly important. The review aims to elucidate the diagnostic accuracy of AI algorithms in screening for all ophthalmic conditions in patient care settings that involve digital imaging modalities, using the reference standa...
Article
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Background: Glaucoma is a significant public health problem due to its substantial increase in the projected number of glaucoma cases. In Ethiopia, glaucoma accounts for 5.2% of irreversible blindness and is the fifth main cause of blindness. The main objective of this study was to modeling time to blindness of left and right eyes of glaucoma patie...
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Technologies are increasingly independent and play important roles in society. Artificial intelligence (AI) is a branch of science that can improve various environments and processes. The health sector stands out among these contexts, especially ophthalmology and dentistry. Studies evaluating the impact of using these technologies in these contexts...
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Automated fundus screening is becoming a significant programme of telemedicine in ophthalmology. Instant quality evaluation of uploaded retinal images could decrease unreliable diagnosis. In this work, we propose fractal dimension of retinal vasculature as an easy, effective and explainable indicator of retinal image quality. The pipeline of our ap...
Article
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Purpose: To evaluate the effect of intranasal mometasone furoate (INMF) on short-term intraocular pressure (IOP) alterations in children with allergic rhinitis (AR). Methods: Children diagnosed with AR and to whom INMF nasal spray had been firstly prescribed were enrolled. Cases with any ocular diseases except for refractive errors were excluded...
Article
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The geriatric nutritional risk index (GNRI) is a nutrition-related risk assessment tool and has been used in various clinical settings. The relationship between body mass index (BMI) and the associated risk of diabetic retinopathy (DR) remains inconclusive. We aimed to evaluate the association between GNRI and DR in patients with type 2 diabetes. W...
Article
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Automatic segmentation of images, which is now feasible through an increase in available computing power, has become an important challenge in many fields. A key technology for obtaining such images is optical coherence tomography (OCT), which is already widely applied in ophthalmology and more recently in the pharmaceutical industry, as a method f...
Book
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A text on medical education.
Presentation
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Introduction: Parkinson's disease (PD) is a neurodegenerative condition those high prevalence ophthalmological symptoms, including visuomotor. The convergence eye movement is an ability to perform a simultaneous eyes adduction. Convergence insufficiency (CI) represents the inability performed this movement. 43.8% of PD population affected by CI, ca...
Article
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Purpose: The present study investigated the long-lasting effect of prematurity, prenatal growth restriction, and associated factors on foveal and peripapillary choroidal thickness in adulthood. Methods: The Gutenberg Prematurity Eye Study (GPES) is a retrospective cohort study with a prospective ophthalmologic examination in Germany. Foveal and...
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Purpose To evaluate the global scientific output of research on ocular chronic Graft versus host disease (cGVHD) and explore the current status and trends in this field over the past decade by bibliometric analysis. Methods The bibliometric search was performed in the Web of Science Core Collection (WoSCC) database. VOSviewer v.1.6.16 was used to...
Article
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Background Collyrium administration is a common procedure in the neonatal ward, both in preterm and at term babies. Various molecules are used to induce mydriasis and cycloplegia: among them, phenylephrine and tropicamide are the most popular, and their administration is generally considered safe. Case presentation A 35 + 2 weeks-old, 2510 g, well...
Article
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Background Punctate inner choroidopathy (PIC) is a rare idiopathic inflammatory multifocal chorioretinopathy. Although the etiology of PIC is unknown, it is proposed to be an autoimmune disease that arises in the context of polygenic susceptibility triggered by an environmental stimulus, such as infection. We reported a case of PIC immediately afte...
Article
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To assess safety and tolerability of intraocularly applied cetuximab as epidermal growth factor receptor antibody, we conducted the experimental study which consisted of groups of adult rabbits (body weight: 2.4 kg) and young rabbits (body weight: 1.6 kg). All animals received three intravitreal injections of 0.5 mg cetuximab (Erbitux) (0.10 mL; 5...
Article
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Purpose We investigated the subjective and objective outcome after intense pulsed light (IPL) treatment and meibomian gland expression on the upper and lower eyelids compared with those after IPL treatment on the lower eyelid alone in patients with moderate-to-severe meibomian gland dysfunction (MGD). Methods Patients who underwent four IPL treatm...
Article
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Background: Numerous studies have pointed out how visual impairment relates to falls in the elderly, causing dangerous consequences, such as fractures. The proximal femur fracture is one of the most frequent fracture types related to poor vision. This study investigates the link between fall-related hip fractures and visual impairment. Methods:...
Article
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Central corneal thickness measurement plays a crucial role in the assessment and treatment of glaucoma and several corneal diseases in addition to its importance in refractive surgery management. There are various methods for central corneal thickness measurement, which differ in their operating principles and technology beside the difference in th...
Article
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Artificial intelligence (AI) has developed rapidly in the field of ophthalmology. Fundus images have become a research hotspot because they are easy to obtain and rich in biological information. The application of fundus image analysis (AI) in background image analysis has been deepened and expanded. At present, a variety of AI studies have been ca...
Article
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Background: The introduction of non-invasive diagnostic tools in ophthalmology has significantly reshaped current clinical practice in different settings. Recently, different anterior segment (AS) intraoperative optical coherence tomography (i-OCT) systems have been employed for different interventional procedures including cataract surgery. Mate...
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Ophthalmic diseases are common among people living with HIV (PLHIV) in developing countries. However, there are currently no published studies on ophthalmic complications among PLHIV in Sierra Leone. We conducted a cross-sectional study of PLHIV presenting at Connaught Hospital in Freetown, Sierra Leone from January through March 2020. Logistic reg...
Article
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Introduction: Ophthalmologists are at a high risk of coronavirus disease 2019 (COVID-19) infection owing to their working environments and proximity to patients during examinations. Compliance with infection control measures in examination offices can lessen the risk of infection to this group. In Egypt, several deaths from COVID-19 have been re...
Article
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Background: Glaucoma has been recognized as one of the leading global causes of irreversible blindness. Patients with primary open-angle glaucoma rarely present with visual symptoms, at least early in the course of the disease. It is important to recognize and treat the disease before there are irreversible changes. Methods: This cross-sectional...
Article
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Background: The World Health Organization (WHO) reported that there are approximately 19 million visually impaired children worldwide, and most of the conditions are treatable by early intervention at the primary, secondary, and tertiary levels. Objective: To assess the status of paediatric eye care services in the Kingdom of Saudi Arabia Methods:...
Article
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Purpose To investigate the effect of different types of convergent strabismus on horizontal eye movements and compare data with healthy control subjects. Materials and methods This prospective, cross-sectional study included 38 patients with convergent strabismus (16 fully accommodative, 13 partially accommodative and 9 non-accommodative esotropia...