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Hello colleagues, I am a recent medical graduate with a strong interest in Obstetrics and Gynecology, actively looking for a research position in this field. I am particularly interested in projects related to reproductive health, maternal outcomes, gynecologic oncology, and health disparities. I am open to both paid and unpaid opportunities and highly motivated to contribute to advancing research in ObGyn. If you have or know of any available positions, I would love to connect.
Thank you for your support!
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Ohh.I just sent the message to the correct email address. I'm so sorry. The mistake was from my end🤦🏽‍♀️.
Thank you so much!
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Hello colleagues, I am a recent medical graduate with a strong interest in Obstetrics and Gynecology, actively looking for a research position in this field. I am particularly interested in projects related to reproductive health, maternal outcomes, gynecologic oncology, and health disparities. I am open to both paid and unpaid opportunities and highly motivated to contribute to advancing research in ObGyn. If you have or know of any available positions, I would love to connect.
Thank you for your support!
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Currently, I am working as an independent researcher, focusing on topics related to obstetrics and gynecology. I am based in Monterrey, Mexico, but I am fully open to relocating for opportunities that align with my career goals and interests.
You can find more about my professional background on my LinkedIn profile: www.linkedin.com/in/karen-yunuén-diego-cruz-92825b28a
Feel free to contact me at my email: karendiegoc@gmail.com
Thank you for your consideration!
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Two case reports (Marketkar et al., 2016 and Akkalp et al., 2015) share the same writing format and appear to have the same literature review. One might argue that because the cancer described is extremely rare, a literature search would result in the same set of articles. However, having an identical table without citing the source raises concerns.
If you see other similarities or have thoughts, please share.
References:
Marketkar, S.P., Hossain, T., Lawrence, W.D., and Quddus, M.R., 2016. Primary Signet-ring Cell Carcinoma of the Uterine Corpus: A Case Report and Review of the Literature. American Journal of Medical Case Reports, 4(2), pp.51-54.
Akkalp, A.K., Ozyurek, E.S., Tetikkurt, U.S., Yalcin, S., Koy, Y., and Usta, A.T., 2015. Primary Endometrial Adenocarcinoma with Signet‐Ring Cells: A Rarely Observed Case and Review of the Literature. Case Reports in Obstetrics and Gynecology, 2015(1), p.404692.
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might not be case of plagiarism because similar rare case may be reported by person in different journal not in same journal but Patients characteristic will be different for each case report
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Describe strategies for managing ethical dilemmas and navigating complex decision-making scenarios in obstetric anaesthesia care.
Managing ethical dilemmas and navigating complex decision-making scenarios in obstetric anesthesia care requires a thoughtful and principled approach that prioritizes patient-centered care, communication, and collaboration among healthcare providers.
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Managing ethical dilemmas and navigating complex decision-making scenarios in obstetric anesthesia care requires a thoughtful and principled approach that prioritizes patient-centered care, communication, and collaboration among healthcare providers. Here are some strategies for effectively addressing ethical dilemmas in obstetric anesthesia:
  1. Adherence to Ethical Principles:Familiarize yourself with ethical principles such as respect for autonomy, beneficence, nonmaleficence, and justice, which provide a framework for ethical decision-making in healthcare. Apply these principles to evaluate the potential risks, benefits, and consequences of anesthesia interventions, considering the interests and well-being of both mother and baby.
  2. Shared Decision-Making:Engage in shared decision-making with pregnant women, involving them in discussions about anesthesia options, risks, and benefits, and supporting them in making informed choices that align with their values, preferences, and cultural beliefs. Foster open and honest communication with patients, encouraging them to ask questions, express concerns, and actively participate in decision-making processes related to their anesthesia care during labor, delivery, and postpartum recovery.
  3. Interprofessional Collaboration:Collaborate closely with obstetricians, midwives, nurses, and other members of the healthcare team to address ethical dilemmas and complex decision-making scenarios effectively. Seek input and perspectives from obstetric colleagues, incorporating their expertise and insights into anesthesia planning, intraoperative management, and postoperative care.
  4. Ethics Consultation:Consider seeking ethics consultation from institutional ethics committees or ethicists when faced with particularly complex or challenging ethical dilemmas that require additional expertise and guidance. Ethics consultation can provide a structured framework for analyzing ethical issues, exploring alternative courses of action, and facilitating resolution while upholding ethical principles and legal requirements.
  5. Ethical Deliberation and Reflection:Engage in ethical deliberation and reflection, individually and as a team, to critically examine ethical dilemmas, clarify values and principles, and consider the potential implications of different courses of action. Take the time to reflect on personal biases, assumptions, and moral beliefs that may influence decision-making and consider how they align with professional ethics and standards of practice.
  6. Documentation and Review:Document ethical considerations, decision-making processes, and interventions in patient records, ensuring that the rationale for clinical decisions and the resolution of ethical dilemmas are clearly documented and accessible for review. Conduct periodic reviews and audits of ethical dilemmas and clinical outcomes to identify opportunities for improvement, address recurring issues, and enhance the ethical climate and quality of care in obstetric anesthesia practice.
By applying these strategies, healthcare providers can effectively manage ethical dilemmas and navigate complex decision-making scenarios in obstetric anesthesia care, promoting patient-centered, ethical, and compassionate care for pregnant women and their babies during childbirth.
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Discuss the legal aspects of obstetric anaesthesia practice, including liability, documentation requirements, and communication with obstetric colleagues and patients.
The legal aspects of obstetric anesthesia practice encompass various considerations related to liability, documentation requirements, and communication with obstetric colleagues and patients.
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The legal aspects of obstetric anesthesia practice encompass various considerations related to liability, documentation requirements, and communication with obstetric colleagues and patients. Here's a discussion of each of these aspects:
  1. Liability:Obstetric anesthesia carries inherent risks, and anesthesiologists must adhere to the standard of care to minimize the risk of adverse outcomes and potential legal liability. Anesthesiologists may be held liable for negligence if they fail to provide care that meets the accepted standard of practice, resulting in harm to the mother or baby. Common areas of liability in obstetric anesthesia include inadequate preoperative assessment, errors in anesthesia administration, failure to recognize and manage complications promptly, and improper postoperative care. To mitigate liability risks, anesthesiologists must stay current with evidence-based guidelines and best practices, maintain appropriate clinical skills and competencies, and communicate effectively with patients and obstetric colleagues.
  2. Documentation Requirements:Comprehensive documentation is essential in obstetric anesthesia to ensure accurate recording of patient information, anesthesia care provided, intraoperative events, and postoperative outcomes. Anesthesia records should include detailed preoperative assessments, anesthesia plans, intraoperative monitoring data, medication administration records, and postoperative assessments. Documentation should be legible, thorough, and contemporaneous, reflecting the timing and sequence of events during labor, delivery, and postpartum care. Accurate documentation serves as a legal record of the care provided, facilitates communication among healthcare providers, supports clinical decision-making, and provides a basis for audit, quality assurance, and medicolegal defense if needed.
  3. Communication with Obstetric Colleagues and Patients:Effective communication with obstetric colleagues, including obstetricians, midwives, nurses, and other members of the healthcare team, is essential for ensuring coordinated care and optimizing patient outcomes. Anesthesiologists should engage in interprofessional collaboration, sharing relevant patient information, anesthesia plans, intraoperative findings, and postoperative considerations to facilitate safe and effective obstetric care. Communication with obstetric patients is critical for obtaining informed consent, providing information about anesthesia options and risks, addressing patient concerns and preferences, and promoting shared decision-making. Anesthesiologists should communicate clearly and compassionately with pregnant women, providing education, answering questions, and offering support to help them make informed decisions about their anesthesia care during labor, delivery, and postpartum recovery.
By addressing these legal aspects of obstetric anesthesia practice, anesthesiologists can help ensure high-quality care, minimize legal risks, and promote positive outcomes for mothers and babies during childbirth. It is essential to remain vigilant, adhere to professional standards, and prioritize patient safety and well-being in all aspects of obstetric anesthesia practice.
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Explain the ethical considerations in obstetric anaesthesia, including maternal autonomy, fetal rights, and informed consent.
Ethical considerations in obstetric anesthesia encompass various principles and dilemmas related to maternal autonomy, fetal rights, and informed consent.
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Ethical considerations in obstetric anesthesia encompass various principles and dilemmas related to maternal autonomy, fetal rights, and informed consent. Here's an explanation of each of these aspects:
  1. Maternal Autonomy:Maternal autonomy refers to a woman's right to make informed decisions about her own healthcare, including choices related to obstetric anesthesia. Ethical considerations regarding maternal autonomy in obstetric anesthesia involve respecting the pregnant woman's right to participate in decision-making regarding pain relief options, anesthesia techniques, and maternal-fetal interventions. Healthcare providers must ensure that pregnant women receive comprehensive information about the benefits, risks, and alternatives of anesthesia options, allowing them to make autonomous decisions that align with their values, preferences, and cultural beliefs. Healthcare providers should engage in shared decision-making with pregnant women, respecting their autonomy while providing guidance and support to help them make informed choices that promote maternal and fetal well-being.
  2. Fetal Rights:Fetal rights refer to the ethical considerations surrounding the protection and respect for the well-being and interests of the fetus during pregnancy and childbirth. Ethical dilemmas may arise in obstetric anesthesia regarding the balance between maternal autonomy and fetal safety, particularly in cases where maternal choices may impact fetal outcomes. Healthcare providers have a duty to consider the potential effects of anesthesia medications and interventions on fetal well-being and to minimize risks to the fetus while providing optimal pain relief and maternal care. Ethical principles such as beneficence and nonmaleficence guide healthcare providers in balancing the interests of both mother and fetus, ensuring that anesthesia interventions prioritize maternal comfort and safety without compromising fetal health and development.
  3. Informed Consent:Informed consent is a fundamental ethical principle that requires healthcare providers to obtain voluntary and informed permission from patients before performing medical interventions or procedures, including obstetric anesthesia. In obstetric anesthesia, obtaining informed consent involves providing pregnant women with clear and comprehensive information about the purpose, risks, benefits, and alternatives of anesthesia options. Healthcare providers should ensure that pregnant women understand the potential effects of anesthesia medications on maternal and fetal outcomes, including risks of maternal hypotension, respiratory depression, and neonatal effects. Informed consent in obstetric anesthesia also includes discussing potential complications and scenarios that may arise during labor, childbirth, and cesarean section, allowing pregnant women to make informed decisions about their care and treatment preferences. Healthcare providers should respect pregnant women's autonomy in consenting to anesthesia interventions, ensuring that they have the opportunity to ask questions, express concerns, and participate in decision-making processes that affect their maternal and fetal health.
In summary, ethical considerations in obstetric anesthesia revolve around respecting maternal autonomy, protecting fetal rights, and obtaining informed consent from pregnant women. Healthcare providers must navigate these ethical dilemmas with sensitivity, empathy, and respect for the autonomy and well-being of both mother and baby. By upholding these ethical principles, healthcare providers can promote patient-centered care and enhance the overall experience of childbirth for pregnant women and their families.
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Outline the considerations for postpartum monitoring, early ambulation, and breastfeeding support in the obstetric anaesthesia setting.
Postpartum monitoring, early ambulation, and breastfeeding support are crucial aspects of obstetric anesthesia care aimed at promoting maternal recovery, ensuring maternal well-being, and facilitating successful breastfeeding.
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Postpartum monitoring, early ambulation, and breastfeeding support are crucial aspects of obstetric anesthesia care aimed at promoting maternal recovery, ensuring maternal well-being, and facilitating successful breastfeeding. Here's an outline of the considerations for each of these components:
1. Postpartum Monitoring:
- Vital Signs: Continuously monitor maternal vital signs, including blood pressure, heart rate, respiratory rate, and oxygen saturation, in the immediate postpartum period and during the recovery phase.
- Pain Assessment: Regularly assess maternal pain intensity using validated pain assessment tools to ensure adequate pain relief and optimize maternal comfort.
- Uterine Tone: Assess uterine tone and involution to monitor postpartum hemorrhage risk and ensure appropriate uterine contraction and healing.
- Bleeding: Monitor vaginal bleeding and assess for signs of excessive bleeding or hemorrhage, particularly in the first 24 hours postpartum.
- Bladder Function: Monitor urinary output and assess for urinary retention or bladder dysfunction, especially in patients who received neuraxial anesthesia.
2. Early Ambulation:
- Encourage early ambulation and mobility as tolerated, starting as soon as possible after delivery, to promote venous return, prevent venous thromboembolism (VTE), and expedite maternal recovery.
- Provide support and assistance as needed for postpartum patients, especially those who underwent cesarean section or experienced significant perineal trauma, to facilitate safe ambulation and mobility.
- Educate patients about the importance of early ambulation, the benefits of physical activity in promoting circulation and preventing complications, and strategies for gradual mobilization and rehabilitation.
3. Breastfeeding Support:
- Facilitate early initiation of breastfeeding within the first hour after delivery to promote bonding, establish breastfeeding success, and provide optimal nutrition for the newborn.
- Provide breastfeeding education and support to postpartum patients, including guidance on proper latch technique, breastfeeding positions, milk production, and management of common breastfeeding challenges.
- Address maternal concerns or difficulties related to breastfeeding, such as nipple pain, engorgement, low milk supply, or breastfeeding difficulties, and offer appropriate interventions or referrals to lactation consultants or support groups as needed.
- Consider the impact of anesthesia medications on breastfeeding and provide guidance on safe medication use during lactation, including recommendations for pain management and medication timing to minimize neonatal exposure.
4. Patient Education and Discharge Planning:
- Provide comprehensive postpartum education to patients and their families regarding self-care, postpartum recovery, warning signs of complications, and when to seek medical attention.
- Develop individualized discharge plans tailored to each patient's needs, including recommendations for pain management, activity restrictions, wound care, contraception, and follow-up care.
- Collaborate with obstetricians, midwives, nurses, and other healthcare providers to ensure continuity of care and support for postpartum patients during the transition to home.
By prioritizing postpartum monitoring, early ambulation, and breastfeeding support in the obstetric anesthesia setting, healthcare providers can optimize maternal recovery, enhance patient satisfaction, and promote positive outcomes for both mother and baby in the postpartum period.
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Explain the considerations for providing anaesthesia in high-risk obstetric patients with multiple comorbidities or obstetric complications.
Providing anesthesia in high-risk obstetric patients with multiple comorbidities or obstetric complications requires a comprehensive approach that takes into account the unique medical and obstetric challenges they present.
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Providing anesthesia in high-risk obstetric patients with multiple comorbidities or obstetric complications requires a comprehensive approach that takes into account the unique medical and obstetric challenges they present. Here are the key considerations:
  1. Preoperative Assessment:Conduct a thorough preoperative assessment to evaluate the patient's medical history, including past obstetric complications, comorbidities (such as hypertension, diabetes, cardiac disease, renal dysfunction), and current medications. Assess the severity of obstetric complications, such as placental abnormalities, uterine rupture, or fetal distress, and their potential impact on anesthesia management. Review relevant imaging studies (e.g., ultrasound, MRI) and laboratory investigations to inform perioperative decision-making.
  2. Multidisciplinary Collaboration:Collaborate closely with obstetricians, maternal-fetal medicine specialists, neonatologists, and other members of the healthcare team to develop a comprehensive management plan tailored to the patient's individual needs. Discuss the patient's medical and obstetric history, anesthesia options, perioperative risks, and potential complications with the multidisciplinary team to ensure a coordinated approach to care.
  3. Choice of Anesthesia:Select the most appropriate anesthesia technique based on the patient's clinical condition, obstetric factors, and surgical requirements. Neuraxial anesthesia (spinal or epidural) is often preferred for cesarean section and some vaginal deliveries in high-risk obstetric patients, as it provides effective pain relief and minimizes the risks associated with general anesthesia. General anesthesia may be indicated in cases where neuraxial anesthesia is contraindicated or unavailable, or in emergent situations requiring rapid maternal intervention.
  4. Optimizing Maternal Physiology:Optimize maternal hemodynamics, including blood pressure, heart rate, and oxygenation, to ensure adequate uteroplacental perfusion and fetal oxygenation. Administer intravenous fluids judiciously to maintain maternal preload and prevent hypotension, especially during neuraxial anesthesia. Consider the use of vasopressors (e.g., phenylephrine) to treat maternal hypotension and maintain systemic perfusion during anesthesia.
  5. Monitoring and Surveillance:Monitor maternal vital signs, including blood pressure, heart rate, respiratory rate, and oxygen saturation, continuously throughout the perioperative period. Utilize continuous electronic fetal heart rate monitoring during labor and delivery to assess fetal well-being and detect signs of fetal distress. Monitor maternal and fetal parameters closely during anesthesia and surgery to detect and manage complications promptly.
  6. Anticipating Complications:Be prepared to manage potential complications associated with anesthesia and obstetric conditions, such as maternal hypotension, hemorrhage, respiratory depression, and fetal distress. Have appropriate resuscitative equipment and medications readily available to address emergent situations and ensure optimal maternal and fetal outcomes.
  7. Postoperative Care:Provide vigilant postoperative monitoring and care for both mother and baby, including assessment of maternal recovery, pain management, and neonatal well-being. Ensure appropriate follow-up care and coordination with obstetric and anesthesia teams to address any postoperative complications or concerns.
By considering these key factors and implementing a multidisciplinary, patient-centered approach, healthcare providers can optimize anesthesia care for high-risk obstetric patients with multiple comorbidities or obstetric complications, ensuring the safest possible outcomes for both mother and baby.
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Discuss the role of regional anaesthesia in managing obstetric emergencies, including its effects on maternal hemodynamics and surgical outcomes.
Regional anaesthesia, particularly neuraxial techniques such as spinal and epidural anesthesia, plays a crucial role in managing obstetric emergencies by providing effective pain relief, facilitating rapid maternal intervention, and minimizing the risks associated with general anesthesia.
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Regional anaesthesia, particularly neuraxial techniques such as spinal and epidural anesthesia, plays a crucial role in managing obstetric emergencies by providing effective pain relief, facilitating rapid maternal intervention, and minimizing the risks associated with general anesthesia. Here's a discussion of the role of regional anaesthesia in obstetric emergencies, including its effects on maternal hemodynamics and surgical outcomes:
  1. Pain Relief and Anesthesia:Neuraxial techniques provide excellent analgesia and anesthesia for labor, vaginal delivery, and cesarean section, allowing for effective pain relief and maternal comfort during obstetric emergencies. Epidural anesthesia can be rapidly initiated and titrated to achieve the desired level of sensory blockade, making it particularly suitable for managing acute labor pain and providing anesthesia for instrumental or operative vaginal delivery. Spinal anesthesia is the preferred technique for emergency cesarean section due to its rapid onset and reliable block height, allowing for prompt maternal intervention and delivery of the baby.
  2. Hemodynamic Stability:Neuraxial anesthesia results in sympathetic blockade, leading to vasodilation and decreased systemic vascular resistance, which can cause maternal hypotension. Maternal hypotension is a common complication of neuraxial anesthesia and can be particularly significant in obstetric emergencies, potentially compromising uteroplacental perfusion and fetal well-being. Prophylactic measures such as preloading with intravenous fluids, left uterine displacement, and administration of vasopressors (e.g., phenylephrine) can help mitigate the risk of maternal hypotension and maintain hemodynamic stability during neuraxial anesthesia.
  3. Surgical Outcomes:Neuraxial anesthesia is associated with favorable surgical outcomes in obstetric emergencies, including cesarean section, compared to general anesthesia. Regional anesthesia allows for rapid initiation of anesthesia and facilitates maternal cooperation and participation in the surgical procedure, which can reduce the need for deep anesthesia and airway manipulation. Compared to general anesthesia, neuraxial anesthesia is associated with reduced maternal morbidity, including decreased risk of aspiration, airway complications, and postoperative nausea and vomiting. Additionally, neuraxial anesthesia provides effective postoperative analgesia, promoting maternal comfort and facilitating early mobilization and recovery after obstetric surgery.
  4. Fetal Effects:Neuraxial anesthesia has minimal direct effects on the fetus, as it does not cross the placenta in significant amounts. Maternal hypotension associated with neuraxial anesthesia can compromise uteroplacental perfusion and fetal oxygenation, leading to fetal distress and acidosis. Close monitoring of fetal heart rate and uterine tone is essential during neuraxial anesthesia to detect signs of fetal compromise and facilitate timely intervention to optimize fetal well-being.
In summary, regional anesthesia, particularly neuraxial techniques, plays a critical role in managing obstetric emergencies by providing effective pain relief, facilitating rapid maternal intervention, and minimizing the risks associated with general anesthesia. While neuraxial anesthesia can result in maternal hypotension, appropriate measures can be implemented to maintain hemodynamic stability and optimize surgical outcomes. Close monitoring of maternal and fetal parameters is essential to ensure maternal and fetal safety during obstetric emergencies managed with regional anesthesia.
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Uterine rupture is a rare but serious obstetric complication characterized by the tearing of the uterine wall, often leading to life-threatening hemorrhage and fetal distress. The anaesthetic management of uterine rupture requires prompt recognition, aggressive resuscitation, and timely intervention to optimize maternal and fetal outcomes.
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Uterine rupture is a rare but serious obstetric complication characterized by the tearing of the uterine wall, often leading to life-threatening hemorrhage and fetal distress. The anaesthetic management of uterine rupture requires prompt recognition, aggressive resuscitation, and timely intervention to optimize maternal and fetal outcomes. Here's an outline of the anaesthetic management:
  1. Preoperative Assessment:Obtain a detailed obstetric history, including any previous uterine surgeries (e.g., cesarean section, myomectomy) or uterine scar formation (e.g., previous uterine rupture). Evaluate the gestational age, fetal status, and maternal comorbidities. Assess for signs and symptoms of uterine rupture, including sudden abdominal pain, vaginal bleeding, fetal distress, and maternal hemodynamic instability. Review any relevant imaging studies (e.g., ultrasound) to assess fetal well-being and confirm the diagnosis of uterine rupture.
  2. Emergency Resuscitation:Initiate immediate resuscitative measures, including supplemental oxygen administration, establishment of large-bore intravenous access, and aggressive fluid resuscitation with crystalloids or blood products as needed. Monitor maternal vital signs, including blood pressure, heart rate, respiratory rate, and oxygen saturation, continuously to assess hemodynamic stability and response to resuscitation efforts.
  3. Choice of Anaesthesia:General anaesthesia is usually indicated for emergency cesarean section in cases of uterine rupture, as it allows for rapid maternal airway control and delivery of the baby. Neuraxial anaesthesia (spinal or epidural) may be considered if the patient is stable and there is no evidence of maternal or fetal compromise, although it may not be appropriate in the setting of severe hemorrhage or fetal distress.
  4. Intraoperative Management: General Anaesthesia:Use rapid sequence induction (RSI) technique to minimize the risk of aspiration and ensure rapid maternal airway control. Administer induction agents and neuromuscular blocking agents cautiously, considering maternal hemodynamics and potential for hemorrhage. Ensure rapid sequence intubation with gentle airway manipulation to minimize the risk of bleeding and ensure adequate oxygenation and ventilation. Neuraxial Anaesthesia:Neuraxial anaesthesia may be considered if the patient is stable and there is no evidence of maternal or fetal compromise, as it provides effective surgical anaesthesia with minimal maternal and fetal effects. Use a lower sensory block height to avoid sympathetic blockade and maintain maternal blood pressure. Monitor maternal vital signs, uterine tone, and fetal heart rate continuously throughout the procedure to assess maternal and fetal well-being and detect signs of worsening uterine rupture or fetal distress.
  5. Surgical Intervention:Perform emergency cesarean section promptly to deliver the baby and address the source of hemorrhage. Minimize uterine manipulation and avoid excessive traction on the uterus to reduce the risk of further uterine injury and hemorrhage. Consider the use of uterotonics (e.g., oxytocin, prostaglandins) to promote uterine contraction and control postpartum hemorrhage.
  6. Postoperative Care:Monitor the mother closely in the immediate postoperative period for signs of bleeding, hemodynamic instability, and other complications. Provide appropriate pain management while considering the risk of respiratory depression and maternal-fetal effects of analgesic medications. Monitor the newborn for signs of neonatal depression, respiratory distress, and other complications requiring intervention or observation.
  7. Multidisciplinary Collaboration:Collaborate closely with obstetricians, maternal-fetal medicine specialists, neonatologists, and other members of the healthcare team to coordinate care and optimize outcomes for both mother and baby. Communicate effectively regarding the maternal condition, anaesthetic plan, and perioperative management strategies to ensure a comprehensive and integrated approach to care.
By following these principles and strategies, healthcare providers can effectively manage the anaesthetic care of patients with uterine rupture, optimizing maternal and fetal outcomes while addressing the unique challenges associated with this obstetric emergency.
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Outline the anaesthetic management of obstetric complications, placental abruption?
Placental abruption is a serious obstetric complication characterized by the premature separation of the placenta from the uterine wall before delivery of the baby. The anaesthetic management of placental abruption is aimed at ensuring maternal and fetal safety while addressing the potential risks associated with hemorrhage and maternal instability.
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Placental abruption is a serious obstetric complication characterized by the premature separation of the placenta from the uterine wall before delivery of the baby. The anaesthetic management of placental abruption is aimed at ensuring maternal and fetal safety while addressing the potential risks associated with hemorrhage and maternal instability. Here's an outline of the anaesthetic management:
  1. Preoperative Assessment:Conduct a thorough assessment of the patient's obstetric history, including the diagnosis of placental abruption, the severity of symptoms, and any previous episodes of bleeding. Evaluate the gestational age, fetal status, and maternal comorbidities. Review any relevant imaging studies (e.g., ultrasound) to assess the extent of placental separation and degree of fetal compromise. Assess the patient's hemodynamic status, airway, and coagulation profile.
  2. Choice of Anaesthesia:Neuraxial anaesthesia (spinal or epidural) is generally preferred for cesarean section in patients with placental abruption, as it provides effective surgical anaesthesia while minimizing the risk of maternal hemorrhage associated with general anaesthesia. General anaesthesia may be indicated in cases where neuraxial anaesthesia is contraindicated or unavailable, or in emergent situations requiring rapid delivery.
  3. Intraoperative Management: Neuraxial Anaesthesia:Preload the patient with intravenous fluids to optimize maternal preload and mitigate the risk of hypotension associated with neuraxial blockade. Use a lower sensory block height to avoid sympathetic blockade and maintain maternal blood pressure. Consider the use of vasopressors (e.g., phenylephrine) to prevent or treat maternal hypotension while minimizing the risk of uterine vasoconstriction. General Anaesthesia:Use rapid sequence induction (RSI) technique to minimize the risk of aspiration and ensure rapid maternal airway control. Administer induction agents and neuromuscular blocking agents cautiously, considering maternal hemodynamics and potential for hemorrhage. Ensure rapid sequence intubation with gentle airway manipulation to minimize the risk of bleeding and ensure adequate oxygenation and ventilation.
  4. Uterine Preservation:Minimize uterine manipulation and avoid excessive traction on the placenta to reduce the risk of further placental separation and hemorrhage. Consider the use of uterotonics (e.g., oxytocin) after delivery to promote uterine contraction and reduce the risk of postpartum hemorrhage.
  5. Postoperative Care:Monitor the mother closely in the immediate postoperative period for signs of bleeding, hemodynamic instability, and other complications. Provide appropriate pain management while considering the risk of respiratory depression and maternal-fetal effects of analgesic medications. Monitor the newborn for signs of neonatal depression, respiratory distress, and other complications requiring intervention or observation.
  6. Multidisciplinary Collaboration:Collaborate closely with obstetricians, maternal-fetal medicine specialists, neonatologists, and other members of the healthcare team to coordinate care and optimize outcomes for both mother and baby. Communicate effectively regarding the maternal condition, anaesthetic plan, and perioperative management strategies to ensure a comprehensive and integrated approach to care.
By following these principles and strategies, healthcare providers can effectively manage the anaesthetic care of patients with placental abruption, optimizing maternal and fetal outcomes while addressing the unique challenges associated with this obstetric complication.
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Outline the anaesthetic management of obstetric complication, placenta previa?
Placenta previa is a condition where the placenta partially or completely covers the cervix, which can lead to severe bleeding during labor and delivery. The anaesthetic management of placenta previa requires careful planning and consideration of the risk of hemorrhage.
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Placenta previa is a condition where the placenta partially or completely covers the cervix, which can lead to severe bleeding during labor and delivery. The anaesthetic management of placenta previa requires careful planning and consideration of the risk of hemorrhage. Here's an outline of the anaesthetic management:
  1. Preoperative Assessment:Obtain a detailed obstetric history, including the diagnosis of placenta previa, the severity of the condition, and any previous episodes of bleeding. Evaluate the gestational age, fetal status, and maternal comorbidities. Review any relevant imaging studies (e.g., ultrasound) to assess placental location and degree of coverage over the cervix. Assess the patient's hemodynamic status, airway, and coagulation profile.
  2. Choice of Anaesthesia:Neuraxial anaesthesia (spinal or epidural) is generally preferred for cesarean section in patients with placenta previa, as it provides effective surgical anaesthesia while minimizing the risk of maternal hemorrhage associated with general anaesthesia. General anaesthesia may be indicated in cases where neuraxial anaesthesia is contraindicated or unavailable, or in emergent situations requiring rapid delivery.
  3. Intraoperative Management: Neuraxial Anaesthesia:Preload the patient with intravenous fluids to optimize maternal preload and mitigate the risk of hypotension associated with neuraxial blockade. Use a lower sensory block height to avoid sympathetic blockade and maintain maternal blood pressure. Consider the use of vasopressors (e.g., phenylephrine) to prevent or treat maternal hypotension while minimizing the risk of uterine vasoconstriction. General Anaesthesia:Use rapid sequence induction (RSI) technique to minimize the risk of aspiration and ensure rapid maternal airway control. Administer induction agents and neuromuscular blocking agents cautiously, considering maternal hemodynamics and potential for hemorrhage. Ensure rapid sequence intubation with gentle airway manipulation to minimize the risk of bleeding and ensure adequate oxygenation and ventilation.
  4. Uterine Preservation:Minimize uterine manipulation and avoid excessive traction on the placenta to reduce the risk of placental separation and hemorrhage. Consider the use of uterotonics (e.g., oxytocin) after delivery to promote uterine contraction and reduce the risk of postpartum hemorrhage.
  5. Postoperative Care:Monitor the mother closely in the immediate postoperative period for signs of bleeding, hemodynamic instability, and other complications. Provide appropriate pain management while considering the risk of respiratory depression and maternal-fetal effects of analgesic medications. Monitor the newborn for signs of neonatal depression, respiratory distress, and other complications requiring intervention or observation.
  6. Multidisciplinary Collaboration:Collaborate closely with obstetricians, maternal-fetal medicine specialists, neonatologists, and other members of the healthcare team to coordinate care and optimize outcomes for both mother and baby. Communicate effectively regarding the maternal condition, anaesthetic plan, and perioperative management strategies to ensure a comprehensive and integrated approach to care.
By following these principles and strategies, healthcare providers can effectively manage the anaesthetic care of patients with placenta previa, optimizing maternal and fetal outcomes while addressing the unique challenges associated with this obstetric complication.
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Outline the anaesthetic management of obstetric complication preeclampsia?
The anaesthetic management of obstetric complication preeclampsia requires careful assessment, monitoring, and intervention to optimize maternal and fetal outcomes while mitigating the risks associated with this condition.
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The anaesthetic management of obstetric complication preeclampsia requires careful assessment, monitoring, and intervention to optimize maternal and fetal outcomes while mitigating the risks associated with this condition. Here's an outline of the anaesthetic management of preeclampsia:
  1. Preoperative Assessment:Obtain a detailed medical history, including the severity and duration of preeclampsia, maternal comorbidities, gestational age, and fetal status. Assess the degree of hypertension, proteinuria, and end-organ involvement (e.g., renal dysfunction, hepatic impairment, neurological symptoms) to determine the severity of preeclampsia and the need for urgent intervention. Review laboratory investigations, including complete blood count, liver function tests, renal function tests, coagulation profile, and assessment of platelet count and function. Evaluate maternal airway status, cardiovascular function, and fluid status to identify potential risks and plan appropriate perioperative management strategies.
  2. Choice of Anaesthesia:Neuraxial anaesthesia (spinal or epidural) is generally preferred for cesarean section in patients with preeclampsia, as it provides effective surgical anaesthesia while minimizing the risk of perioperative complications associated with general anaesthesia. General anaesthesia may be indicated in cases where neuraxial anaesthesia is contraindicated or unavailable, or in emergent situations requiring rapid delivery.
  3. Intraoperative Management: Neuraxial Anaesthesia:Preload the patient with intravenous fluids to optimize maternal preload and mitigate the risk of hypotension associated with neuraxial blockade. Consider prophylactic vasopressor administration (e.g., phenylephrine infusion) to prevent or treat maternal hypotension during neuraxial anaesthesia. Monitor maternal blood pressure, heart rate, oxygen saturation, and uterine perfusion continuously throughout the procedure. General Anaesthesia:Use rapid sequence induction (RSI) technique to minimize the risk of aspiration pneumonitis and ensure rapid maternal airway control. Administer induction agents and neuromuscular blocking agents cautiously, considering maternal hemodynamics and fetal well-being. Intubate the trachea with care to avoid hemodynamic instability and ensure adequate oxygenation and ventilation.
  4. Postoperative Care:Monitor the mother closely in the immediate postoperative period for signs of worsening preeclampsia, including hypertension, proteinuria, and signs of end-organ dysfunction. Provide appropriate pain management while considering the maternal-fetal effects of analgesic medications. Monitor the newborn for signs of neonatal depression, respiratory distress, and other complications requiring intervention or observation. Ensure appropriate follow-up care for both mother and baby, including monitoring of blood pressure, renal function, and coagulation status in the mother, and assessment of neonatal well-being.
  5. Multidisciplinary Collaboration:Collaborate closely with obstetricians, maternal-fetal medicine specialists, neonatologists, and other members of the healthcare team to coordinate care and optimize outcomes for both mother and baby. Communicate effectively regarding the maternal condition, anaesthetic plan, and perioperative management strategies to ensure a comprehensive and integrated approach to care.
  6. Emergent Situations:Be prepared to manage emergent complications associated with preeclampsia, such as eclampsia (seizures), HELLP syndrome (hemolysis, elevated liver enzymes, low platelets), or pulmonary edema, with prompt recognition and intervention to stabilize the mother and fetus.
By following these principles and strategies, healthcare providers can effectively manage the anaesthetic care of patients with preeclampsia, optimizing maternal and fetal outcomes while addressing the unique challenges associated with this obstetric complication.
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Describe strategies for minimizing fetal exposure to anaesthetic agents and optimizing fetal well-being during obstetric anaesthesia.
Minimizing fetal exposure to anaesthetic agents and optimizing fetal well-being during obstetric anaesthesia requires careful planning, monitoring, and intervention.
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Minimizing fetal exposure to anaesthetic agents and optimizing fetal well-being during obstetric anaesthesia requires careful planning, monitoring, and intervention. Here are strategies to achieve these goals:
  1. Preoperative Assessment and Planning:Conduct a thorough preoperative assessment of the pregnant patient, including obstetric history, gestational age, fetal well-being, and maternal medical conditions. Review medications and allergies to minimize the risk of adverse drug reactions or interactions. Consider the urgency of the procedure and maternal-fetal status when selecting the appropriate anaesthesia technique. Discuss anaesthetic options, risks, and benefits with the patient, involving shared decision-making in the choice of anaesthesia technique.
  2. Optimizing Maternal Physiology:Ensure adequate maternal hydration and positioning to optimize maternal hemodynamics and uteroplacental perfusion. Administer intravenous fluids judiciously to maintain maternal preload and prevent hypotension during neuraxial anaesthesia. Consider prophylactic vasopressor administration (e.g., phenylephrine) to counteract neuraxial-induced hypotension and maintain maternal blood pressure.
  3. Minimizing Fetal Exposure to Anaesthetic Agents:Use regional anaesthesia techniques (spinal or epidural) whenever feasible for both labour analgesia and cesarean section to minimize fetal exposure to systemic medications. Limit the use of systemic medications with high placental transfer and potential for fetal depression (e.g., opioids, sedatives) to cases where neuraxial anaesthesia is contraindicated or unavailable. Use the lowest effective dose of medications and avoid unnecessary drug administration to minimize fetal exposure and adverse effects.
  4. Continuous Monitoring of Maternal and Fetal Parameters:Continuously monitor maternal vital signs, including blood pressure, heart rate, and oxygen saturation, throughout the perioperative period. Utilize continuous electronic fetal heart rate monitoring during labour and cesarean section to assess fetal well-being and detect signs of fetal distress. Maintain vigilant surveillance for nonreassuring fetal heart rate patterns or other signs of fetal compromise, prompting timely intervention to optimize fetal oxygenation and perfusion.
  5. Optimizing Maternal Oxygenation:Ensure adequate preoxygenation and ventilation during intubation and general anaesthesia induction to minimize maternal and fetal hypoxia. Consider the use of high-flow nasal oxygenation or noninvasive ventilation techniques to optimize maternal oxygenation and prevent maternal hypoxemia.
  6. Postoperative Monitoring and Neonatal Care:Provide appropriate postoperative monitoring and care for both the mother and newborn, including assessment of maternal recovery, pain management, and neonatal respiratory status. Implement neonatal resuscitation protocols as needed to manage neonatal depression or respiratory distress, ensuring prompt recognition and intervention to optimize neonatal outcomes.
  7. Communication and Collaboration:Foster effective communication and collaboration among obstetricians, anaesthesiologists, neonatologists, and other members of the healthcare team to coordinate care and optimize outcomes for both mother and baby. Discuss management plans and contingency measures for potential complications, ensuring readiness to address emergent situations promptly and effectively.
By implementing these strategies, healthcare providers can minimize fetal exposure to anaesthetic agents and optimize fetal well-being during obstetric anaesthesia, ensuring the safest possible outcomes for both mother and baby.
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Massive obstetric haemorrhage (MOH) remains a leading cause of maternal mortality worldwide, accounting for up to 50% of maternal deaths in some countries and currently constitutes the seventh commonest cause of death in the United Kingdom with a rate of 0.6/100,000 maternities.
Optimum management of this condition require up to date knowledge of relevant treatment modalities (such as Tranexamic Acid and interventional radiology), competent surgical techniques and an appreciation of non-technical skills (i.e. human factors). In particular, decision making and speed of action by the most experienced clinician present (often the registrar) is paramount so that obstetric haemorrhage could be controlled before it deteriorated to coagulopathy and ultimately maternal death.
For this issue, the editors aim to garner a collection of articles to cover the broad aspects pertaining to MOH for the benefit of clinicians and patients alike.
The potential applications encompass a wide spectrum and include, but are not restricted to, the following areas:
  • Human factors in MOH.
  • Cell salvage technology in MOH.
  • Top tips on bedside visual estimation of blood loss.
  • Pelvic packing in PPH: A review of worldwide literature.
  • The role of Interventional Radiology in MOH.
  • The role of Tranexamic Acid in MOH: Review of Evidence
  • Placenta Accreta Spectrum.
  • Management of women who decline blood transfusion.
  • Uterine compression sutures: Which ones should we use?
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The patient is 4 days postpartum after a physiological delivery. Complaints of unbearable pain in the perineum and lumbar pain. There were minor internal tears. On examination, there is no inflammation, no swelling. Pain relief with ketoprofen is of little help. Can you please advise how to anaesthetise or partially relieve the pain?
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Volodymyr, it is important to find the reason of the pain.
- Infection (endometritis, perineal, UTI)?
- Urinary retention?
- Haematoma or other trauma?
- Neurological? (for example from sacral plexus or pudendus?)
Women postpartum generally can receive both paracetamol and NSAID, some few days of Oxykodon can be okay if the neonatologists are fine with it (or if she is not breastfeeding). In some cases, epidural or nerve block can help postpartum also. But the priority is to find out what's the problem, not just releive pain.
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Dear scholars!
I have collected data on the met need for EMOC (Having expected obstetric complications, treated obstetric complications, and the met need in percentage) of certain countries. Can I do a descriptive meta-analysis?
What commands in Stata can I use?
I wanted to use CMA, but it's not freely accessible.
thanks.
Melese
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The metan command in Stata is used to perform a descriptive meta-analysis. To do this, the estimates must be converted to proportions by dividing by 100. The "metan" command will generate a forest plot showing the summary estimate and confidence intervals for the met need for EMOC in each country. The results can be interpreted based on the summary estimates and uncertainty around them. By using the metan command in Stata, users can perform a descriptive meta-analysis without relying on external software like CMA.
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Obstetrics has technically avoided descent in breech presenting fetus. How can this be assessed when there is room to plot 'w' in new WHO partograph?
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Per abdominal assessed not enter in brim
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What are the causes of antenatal and postnatal ascites?
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Hypoproteinemia
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 84% of Jordan population have vitamin D deficiency 
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Following, a link for answering to some questions on Intraepathic Cholestasis of Pregnancy
The survey is organized by th Clinical & Experimental Obstetrics and Gynecology Journal and results will be published on that journal (open).
I thank in advace people who will answer
Dr Ugo Indraccolo, M.D., Ph.D.
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Waiting for recommendations and guidelines. Involve neonatologists too.
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§ Dennis-Antwi, J. A. (2012). Role of Midwives in Reducing Maternal Mortality in Africa: Invited presentations and presentations by organisations and societies .International Journal of Gynecology & Obstetrics, Volume 119, Issue S3. https://doi.org/10.1016/S0020-7292(12)60122-2
§ F. Day-Stirk, S. Pairman, R. Jolivet, S. Downe, J. Dennis-Antwi, A. Gheressi (2012). Education and Evidence – The Foundations of Effective Maternal And Newborn Care, International Journal of Gynecology & Obstetrics 10/2012; 119:S181. https://doi.org/10.1016/S0020-7292(12)60116-7
Dennis-Antwi J.A, (2011b) Preceptorship for Midwifery Practice in Africa: Challenges and Opportunities. Evidence Based Midwifery 9(4): 137-142 http://www.rcm.org.uk/ebm/ebm-2011/volume-9-issue-4/preceptorship-for-midwifery-practice-in-africa-challenges-and-opportunities/
  • Dennis-Antwi J.A, (2010b) Achievement of MDGs 4-6: The role of the Midwife. West Africa College of Nursing 2010; 21(2):99-101 (Nursing News)
Dennis-Antwi, J. (1997) Sickle cell disease in Ghana. Africa Health Journal 19 (2): 14-15
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hi, add in the profile next to overview ...there is research where you should add the article
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In your personal experience,How do you manage your life and make a balance between work, family and other related sections!?:)
I would be thrilled to have your points!
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Equally, dear Dr. Hossein
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For a project I am working on, I would like to know where I can access public and free image data-sets.
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I have a research about surgical anatomy in OBGYN, and would like to invite gynaecologists with interest in the topic to take an active part in the project.
Regards,
Ismaiel
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I am interested in the topic
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Like a new, better way of performing C-sections or avoiding pregnancy complications?
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Single port laparoscopy and single port robotic assisted laparoscopic surgery.
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Is there any information about the features of the intestinal microbiome in pre-eclampsia ?
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Please see the following RG link.
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Which resource or what is the most reliable reference/website/textbook to check when looking for the safety of medications during pregnancy?
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Food Drug Administration USA ( USA), Harrison's principles of internal medicine
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We like to share our experience in research in small group discussion
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Welcome Dr Tanaka. Nice to see u there
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There is a uterine prolapse (Last degree) and there is an ulcer. The Q is how can the patient apply the cream prescribed for the ulcer along with the antiseptic and Gauze (Also Vaseline is prescribed).
Is the cream (Mebo cream aids in healing) applied on the ulcer only?, and we impregnate the gauze with the antiseptic (Betadine) and apply it on the cervix and the vagina only, or apply it on the entire prolapsed uterus, and if so, how? Because as we previously applied the cream on the ulcer, so there will be overlapping of two ingredients (Mebo and Betadine) ? And finally how we raise the uterus with the Gauze?
I downloaded the image for illustration.
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Recommended treatment. For decubitus ulcer includes
1. Reduction
2. Ring pessary
3. Estrogen cream
Without pesaary there will be no improvement due to persistent cause which is tiusse necrosis.
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Please see the following:
The Labile Side of Iron Supplementation in CKD
Itzchak Slotki* and Zvi Ioav Cabantchik†
*Division of Adult Nephrology, Shaare Zedek Medical Center and Hadassah Hebrew University of Jerusalem, Jerusalem,
Israel; and †Department of Biological Chemistry, Alexander Silberman Institute of Life Sciences, The Hebrew University of
Jerusalem, Jerusalem, Israel
ABSTRACT
The practice of intravenous iron supplementation has grown as nephrologists have
gradually moved away from the liberal use of erythropoiesis-stimulating agents
as the main treatment for the anemia of CKD. This approach, together with the
introduction of large-dose iron preparations, raises the future specter of inadvertent
iatrogenic iron toxicity. Concerns have been raised in original studies and reviews
about cardiac complications and severe infections that result from long-term
intravenous iron supplementation. 
J Am Soc Nephrol 26: 2612–2619, 2015. doi: 10.1681/ASN.2015010052
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Most food species provide the required amount of iron. However, the body needs large amounts of iron during pregnancy. The additional amount is given throughout the pregnancy, as well as within 2 - 3 months after birth, to compensate the iron reserve in the body of the woman after birth. Deficiency symptoms Iron deficiency leads to anemia, which includes symptoms of fatigue, fatigue, shortness of breath and rapid heartbeat. It can also show apathy, irritability and decreased body ability to resist infections. Symptoms and risks in overdose Iron poisoning is very serious. The symptoms are: abdominal pain, nausea and vomiting, accompanied by high body temperature, abdominal distension, dryness and a serious reduction in blood pressure. These conditions require immediate medical treatment. Pharmaceutical preparations Iron sulphate, iron fumarate, iron gluconate and iron compound - polysaccharides can be obtained over-the-counter in medical preparations, vitamins and minerals. Dextran iron given by injection can only be obtained by prescription and at bedtime. Liver sources is the best source of iron. Meat (especially brains and kidneys), eggs, chicken, fish, green leafy vegetables, dried fruits, whole or fortified cereals, bread and some baked goods, nuts and dried pulses are all rich sources of iron. Iron, which comes from meat, chicken and fish, is better absorbed than iron, which comes from vegetables. The dose is determined individually, depending on the nature and severity of the condition. In adults, anemia is usually treated with a dose of 30-100 mg of iron, two or three times a day. In children, the dosage should be reduced by generation and weight. In the case of pregnancy it is recommended to give between 30 - 60 mg per day. Recommended daily dose Details of recommended daily amount (RDA) for iron, 10 mg (from birth to 6 months), 15 mg (from 6 months to 3 years), 10 mg (4 to 10 years) 18 mg (for males between the ages of 11 to 18 years - for females from the age of 11 years to 50 years), 10 mg (for males aged 19 years and above and for females aged 51 and above) the body needs a larger amount during pregnancy and up to two or three months after Birth. I have foods that contain vitamin and iron
 
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The main aim is to find predictors of a mother getting an episiotmy in a CY program environment (CY program - Chiranjeevi Yojana (CY) – a program that enables poor mothers free delivery in private facilities)
The total data set is of 1268 mothers who were surveyed soon after they birthed in public and private obstetric facilities in three districts. The question on episiotomy was analysed for 1048 mothers (excluding those who had a caesarean)
Dependent variable: Episiotomy (f5cq7) (0.No, 1.Yes)
Independent Variables:
I have attached a word document with this request.
Can someone helpme with this please?
Thanks a lot,
Veena
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Dr. Iyer,
I have looked at your stata output which shows you have used Poisson Regression. So before your specific question can be answered, I must first point out that Poisson is not appropriate for a dichotomous variable such as episiotomy (Yes/No). Poisson is only appropriate for a count variable as the dependent variable (e.g. number of children; or number of episiotomies a women have had).
For your variable, a binary logistic regression (LR) will be more appropriate. Coincidently I wrote a paper in 2007 on episiotomy, using logistic regression. Although have used LR very frequently lately, I have attached my episiotomy paper for you. I hope it helps.
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Let’s bring obstetric fistula back to the forefront of global conversation and ensure that no woman is left behind, especially the most vulnerable and disadvantaged.  
It’s a life shattering condition affecting two million women in 55 low resource countries of Sub-Saharan Africa and South Asia; with up to 100,000 additional women tragically developing a fistula every year in some of the world’s poorest and most disadvantaged communities.
For every woman who receives treatment for her fistula, at least 50 more go without because of a global shortage of trained, skilled fistula surgeons, and a huge unmet need to treat and repair the backlog of women suffering from this condition.
There is an essential need for more surgeons to be trained on fistula repair and for more health facilities to provide holistic fistula treatment services, including rehabilitation and social assistance.
Let’s bring obstetric fistula back to the forefront of global conversation and ensure that no woman is left behind, especially the most vulnerable and diasdvantaged.  
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Dear Sir,
before we think on number of surgeons that we need, it can be useful to think on risk factors leading to fistula. among those factors includes young marriage, obstructed labor, low interval in child spacing, home delivery and others. these factors have to be prevented as well as increasing qualified Dr for treatment.
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Some medical professionals in our country believe that if amniotic sac sac stays intact during giving birth, it needs to be artificially broken at least at cca 8 cm of cervical opening during the first stage of labor. They believe pushing with intact membranes can otherwise CAUSE placental abruption, which is dangerous for both mother and a child. What is the origin of this claim ? Is there any evidence supporting or refuting it ?
(I have seen a Cochrane review, which does NOT recommend a routine amniotomy during first stage of labor. Frustratingly, though, in that article, amniotomy is framed only as a measure to speed up labor. Placental abruption is not among the outcomes. )
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Amniotomy may hasten Labour progression by allowing fetal axis pressure to come into play early and hasten the release of prostaglandins , all which may impact positively on Labour progression but not necessarily Labour outcome has been well documented.
Similarly amniotomy is a well documented integral and cardinal component of management of placental abduction but not it's prevention. Of crucial significance is the fact amniotomy should be performed in a controlled fashion in order to prevent sudden decompression of intrauterine pressure particularly in cases of uterine overdistension due to e.g. polyhydramnios which may then predispose to placental abduction.
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Dear all
How can I analysis the picture of intracellular GSH and ROS in embryos? I have the picture of both of them (GSH and ROS) and also ImageJ. Is there any Excel formula? if so please send me through my e-mail (dipupstu2012@pstu.ac.bd) or (dibyenducvasu@gmail.com)
Thanks in advance
Dibyendu Biswas
Dept of Medicine, Surgery and Obstetrics
Patuakhali Science and Technology University
Bangladesh
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Any tool to measure the postnatal quality of life would be perfect.
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If someone found the MGI tool, kindly share.
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We found that some obstetricians conserve these fetuses but with poor outcomes
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In the US, women who experience PPROM should be transferred to a Level 3 medical center that has the highest level nursery care available. The woman should be given a betamethasone steroid injection to promote fetal lung maturity. Magnesium sulfate is administered for neuroprotection and should be administered to reduce the incidence of long-term neurological injuries. Antibiotics should be administered to reduce the risk of infection. Maternal vital signs and electronic fetal monitoring should be ongoing. If the maternal temperature begins to increase, chorioamniocitis should be suspected and immediate  cesarean is indicated. The use of tocolytics is no longer recommended for long-term use but may be considered for up to 48 hours when PTL does not stop to give the corticosteroids time to improve fetal lung maturity.
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Does anyone know of any specific guidelines (UK, europe or US) for follow up of patients with preeclampsia or gestational diabetes post delivery?
In particular  which patients to follow up, when to start and stop follow up, what parameters to measure and how often (e.g. 3-monthly, yearly?).
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For gestational diabetes, in the US, ACOG recommends a 2 hour Glucose Tolerance Test to be done at the 6 weeks post partum visit to screen for Type 2 Diabetes with our gestational diabetics.
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Patient is married from last 5 years and has a child. Now she has difficulty in conceiving the second child. She is on Metformin 500mg twice a day.
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Laparoscopic ovarian drilling can be of help. Ofcource she may be advice on weight reduction if she is overweight
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I can't find any case report about it 
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Interesting case, it would be important to know/report on;
how they removed the subserosal fibroid, did they tie off the base and leave a good nubbin of fibroid tissue or did they shave the myometrium in the process; did they use adhesion prevention techniques or did an adhesion attached to the operative site rent the defect in later pregnancy. Was the original fibroid a solitary lesion or was it a multi-fibroid uterus, and one of the intramural fibroids undergo degeneration in pregnancy (predisposing to rupture). All the best.
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what is the best management?
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Thanks Jelena
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I assume this is an haematoma... But which exams will be mandatory after she'll give birth to her boy ?
Thank you
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Haematoma can occur in pregnancy. Adrenal mass detected during pregnancy is very uncommon. Because pheochromocytoma in pregnancy is associated with high mortality and morbidity, it always to be excluded. Because of nonenhanced and non hormonal nature of mass, pheochromocytoma is very unlikely in this patient. However contrast CTScan of whole abdomen will be helpful in this case.. MRI of abdomen will be also helpful. Cortisol estimation to done after delivery to look for late development of hypofunction of adrenal which can occur after adrenal haemorrhage to avoid adrenal crisis. 
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1.     32 y.o pregnant female presented to the ER complaining of headache, fever and vomiting. LP was done. CSF was cloudy and CSF analysis showed: low glucose, elevated protein, and high WBCs with the presence of neutrophils. Patient was started on Vancomycin, Ceftriaxone, and Acyclovir as empiric therapy. CSF culture showed gram positive diplococcus bacteria so Acyclovir was discontinued. Ceftriaxone and Vancomycin were continued.
·      Was anything missing in the empiric therapy?
·      What is wrong in the management?
·      What is your choice of antibiotics to treat her?
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although rare, tuberculous meningitis also should be checked, since it can concomittantly occur.  More detailed information about her pregnancy status should have been given for such a patient. 
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We experienced profuse, unexplained bleeding, unusual than routine, during surgical fixation of comminuted acute subtrochanteric fracture that was managed by locking plate fixation. Cephalomedullar nail could not be done due to fracture personality.
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 I disagree with the general opinion that lactating women have a higher  risk of thromboembolic complications because of higher levels of prolactin. There are some evidence that  prolactin has an indirect inhibitory effect  on platelets in hyperprolactinemic patients, suggesting that prolactin might have a protective role in thromboembolic disease. So I believe excessive bleeding could be expected in such patients operated on emergency basis.
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Transverse myelitis is easily missed in most African countries where time is wasted treating patients for malaria even though negative and other related symptoms
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Thank you so much Dhia. I appreciate your response and above all, some good literature.
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CT and MRI of the pelvis with contrast, confirmed no evidence of bowel/vaginal fistula.
Hysteroscopy biopsy showed no malignancy
The patient had tubal sterilisation 30 years ago
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I think that we are in front of a case of severe vaginal discharge may be due to chronic infection associated with immune disturbance , vaginal swap and culture may be benificial 
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The risk in prenatal screening tests is hard to visualize for some patients.  
Not everybody is familiar with the meaning of statistical risk.
So sometimes it is important to explain patients their risk status with some examples.  While some consider 1/ 250 as a relaxing result for their trisomy 21 risk, some couples are very much scared and anxious by a result of 1/650, for example. 
This is also true for operational (surgical) risks, or for any risk that comes with the nature of any intervention, such as amniocentesis, cordocentesis, chorion villus biopsy.
What are your examples to explain "a risk associated with a procedure" to a person who does not have an idea of statistical risk?
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Big numbers beyond say 1 in 10 represent a challenge to many patients but many can relate to days of the year. So if a risk is 1 in 750 you could give as an example - if you pick a date sometime in the next 2 years and I can correctly guess the date, that is about 1 in 700.
For 1 in 18000 you could say if you pick a date sometime in the next 5 years and I can correctly guess the date, that is about 1 in 18000. 
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Does anybody have experience with the use of the Glucommander computer algorithm for glucose management in pregnant women needing intravenous insulin infusion in hospital, with and without DKA? I am searching for recommended settings to start with for pregnancy which have been tested by others.
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Dear, I have no knowledge.
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I have read the recent withdrawal of the recommendation to use Diclectin for morning sickness. Pyridoxine is recommended in its place. Diclectin contains 10 mg, but the smallest dose of pyridoxine I can find at the pharmacy is 100 mg. I would like some opinions from obstetricians and midwives as to what dose they recommend.
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The above comments confirm that there is no published research about taking oral pills of B6 for nausea and vomiting during pregnancy.  My experience as a midwife for 35 years shows that B6 has no positive effect on NVP during  pregnancy.  Perhaps because the women are too sick to take pills. Or it is just too late.  The above comments imply that too much is harmful but only fat soluble vitamins can be toxic . B6 is water soluble and excess is urinated in the urine.
I have found that taking 50 mg a day for 3 months before conception prevents NVP.    I published this.    50 mg dose is available at www.puritan.Com for $6 for 3 month supply
A 10 mg dose would also do it, but I can no longer find less than 50 mg to buy
Women taking B complex pills with B6 inside found no deceased NVP during pregnancy, so encourage only B6 not B complex. 
I know of no other researchers who research the use of B6 to prevent NVP.  Would be interested in hearing from any one like that.
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I'm very interested in this maneuver because it is common practice though there is little evidence on it.
who has interesting research ideas on this topic? who has already useful protocols and instruction tools for this maneuver?
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Cars are for the most part reliable.   However, when a certain tire is found to be faulty and risk the lives of 1 in 100,000 users,  it is taken off the market.  NO RCT STUDY IS DONE.  It is taken off the market because it might kill a man or two.  But not so when women are involved.   Killing a woman here or there is just irrelevant collateral damage, according to the person who thinks we need an RCT to know if fundal pressure is dangerous.  Because here we have in this discussion, experienced practitioners with decades of experience who say,  FUNDAL PRESSURE WILL DIRECTLY CAUSE UTERINE RUPTURE and/or destruction of the spleen, both of which are life changing events and sometimes life ending events.  And it is not as if anything bad would have happened if you DID NOT DO FUNDAL PRESSURE.  The baby would have delivered for sure.  Fundal pressure just satisfied the need to move the woman out of labor and delivery ward.   At least when a tire is faulty, well the car was useful at getting the person to another location. But fundal pressure has no need to be used at all.   All those babies will come out, just a bit later.   And the kind owners of the RESEARCHGATE.NET give us a method of communicating facts to each other, so that we dont have to reinvent the wheel and do unnecessary RCT studies about KNOWN PROTOCOLS THAT KILL AND MAIM WOMEN,  like the known and ever present DANGERS of fundal pressure.  Cathleen Gavel obviously is young  and thinks she just discovered some terrific way to deliver babies by using fundal pressure instead of letting the uterus and the mother push it out.   Instead of learning from others,  she wants an RCT .    That defies all logic.  And everyone on this list who has worked for 20 years or more knows it.    Obviously when people are being observed in an RCT, they will be extra careful not to explode the spleen, and the study will be small and not large enough to wait for the inevitable uterine rupture or spleen explosion.   After FUNDAL PRESSURE Is found to be supposedly safe in some study that has not enough participants to say anything, god forbid, then people will go back to rupturing uterus and exploding spleens and now they can do it without remorse because of some small RCT study, by someone who is resistant to listening to people with 35 years of experience,   says so.    To hear anyone say that a RCT study of FUNDAL PRESSURE IS needed, is like saying we need a RCT study to see if we should use hair dryers while in the shower, or whether female genital mutilation, removing the clitoris, increases female sexual pleasure etc etc.    If the purpose of the study is to justify killing women, then it is a very good idea to do a RCT on Fundal pressure.   
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It is common obstetric knowledge full bladder cause secondary labour dystocia. But how much urine is necessary and which amount legalize a urinary catheterisation? 
Thanks for your help
A happy new year
Peggy
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During active labour patient is encouraged to pass urine 1-2 hourly according to the local protocol. If the quantity passed is inadequate and and on clinical examination her contractions which were good have now slowed down then I would consider catheterisation. The amount may be just 100 -200 mls only. I might consider self -retaining catheter if I this problem is recurring and remove the catheter when she is fully dilated and ready to deliver.
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During the last decade there are more and more articles dealing with antibiotic treatment of uncomplicated acute appendicitis. But there are no data about pregnant population with suspected acute appendicitis. I published a 2nd edition of my book on the subject:
but there are no data about this topic.
Studies claim that appendectomy for uncomplicated acute appendicitis, negative appendectomy and general pregnant population have the same fetal loss rate of 2-4%. Current conclusion is that (laparoscopic) appendectomy is completely safe in pregnancy and that obstetric complications are the consequence of the severity of the disease.
Do you have and ideas or articles dealing with the subject.
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= How do you know it is appendicitis?  Do you have a  fail safe criterion (criteria) to distinguish what is an "uncomplicated" versus a "complicated appendicitis? The only criterion I know is watching  the progression/regression  of the clinical signs and symptoms every 6 hours, without giving antibiotics nor pain killers. This is true for all patients except the pediatric cases and those whose affect obscure the  interpretation of your objectivity. ... and your labs will  then function as confirmatory tests as they are supposed to do.  
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The focus of the study is how can the physical environment of childbirth influence restoration of  women? I am looking for how best to collect data on the experiences of women who give birth in the hospital obstetric units. Literature suggests that for a well woman who had a normal delivery, the duration of discharge from hospital is between 24-48hours sometimes, some women could be discharged less than 24 hours. Given this situation, how best do you think I can collect the data and in addition, how can one possibly avoid the experience of childbirth from interfering with that of recovery/restoration?
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This sounds like a useful and informative study - assuming the methods you select are feasible for your circumstances. My first thought, when I read the word restorative, is the work of Kaplan and Kaplan who study attention restoration and developed a comprehensive theory ART (attention restoration theory) - though this is not what you are describing - I thought I'd point out the overlap. Meanwhile, I am one of the colleagues Dr Newnham referred to above. I have multiple publications regarding the physical birth unit design's influence on women's supporters' experiences. It is a 'wicked' problem - better understanding the space in which such a number of different experiences occur (caregivers, the woman, the supporters). There isn't necessarily one best method - but making sure that you are connecting your well-developed research question very clearly with the population of interest and the existing literature and the possible outcomes is important. 
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Dear Nurussolehah Yusof,
Here I send you a paper we wrote about it:
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mitogen-activated protein kinases
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There are some articles on abortion.
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One of the only things missing from YouTube is a triplet home birth. I am looking for a woman willing to deliver her full term triplets at home and post the video example to counter the endless effort to define labor and delivery as extreme sport.  Safe triplet deliver at term would be fairly easily accomplished because triplets are small and it is possible to deliver all three within 10 minutes if the woman pushed in squatting, with some coaching.
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Triplet pregnancy
In my country, not recommended triple birth pregnancies at home
The exceptions to vaginal delivery include the following:
Presenting triplet in breech position
Conjoined twin anatomy
Most cases of mono-amniotic twins
Signs of fetal distress or an abnormality that warrants abdominal delivery
Higher order births
In my country, cesarean delivery is planned for higher order births
Although the frequency of multiple gestations is lower than singleton gestations, multiple gestations account for a disproportionate share of neonatal morbidity and mortality. Much of this can be attributed to a higher rate of preterm delivery for multiple gestations. The mean gestational age at delivery is 35 weeks for twins, 32 weeks for triplets and 29 weeks for quadruplets. As a result, 25% of twins and 75% of triplets require admission to the neonatal intensive care unit (NICU). Neurologic outcomes also appear to be worse in multiple births. When matched for gestational age at delivery, infants born from multifetal pregnancies have an approximately 3-fold increase in cerebral palsy (see the Gestational Age from Estimated Date of Delivery calculator). There is an approximate fivefold increased risk of stillbirth and sevenfold increased risk of neonatal death.
Monochorionic gestations are at risk for twin twin transfusion syndrome (TTTS) which can occur about 15% of monochorionic pregnancies. TTTS is thought to be caused by vascular anastomoses within the placenta causing one twin to become underperfused (the "donor" twin) and the other twin to show signs of overperfusion (the "recipient" twin). Pregnancies complicated by TTTS are at significantly increased risk of neonatal morbidity and mortality.
Maternal morbidity is also increased in a multifetal gestation. Women with multiples are more likely to be hospitalized with complications including preterm labor, preterm premature rupture of membranes, preeclampsia, placental abruption, pulmonary embolism, and postpartum hemorrhage. As a result, hospital costs are higher in these pregnancies.
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in the lithotomy position, we lose the help of the gravity
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Women used a variety of birth positions and a majority gave birth in flexible sacrum positions. No associations were found between flexible sacrum positions and SPT. Flexible sacrum positions were associated with fewer episiotomies.
Perineal injuries and birth positions among 2992 women with a low risk pregnancy who opted for a homebirth
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The survey i'm looking for should deal with womens perseptions about the terms the organization should provide to mothers who want to continue breastfeeding doring returnning to  work
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Maybe the following could be useful?
Regards,
Sevgi.
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A 33 yr woman with 8.4 weeks estimated gestational age with last menstrual period revealed following reports on transvaginal ultra-sonography:
1. Bulky uterus
2. Single gestation sac of about 5.43X4.62X3.34 cm size in uterine cavity.
3. Crown to rump length of embryo is 16.3 mm which correspond to 8.2 weeks of gestation.
4. Normal yolk sac seen in gestation sac.
5. Trophoblastic rim is normal in thickness and ecogenicity. A small anechoic area seen right laterally.
6. Gestation sac contains single embroyo without cardiac pulsations.
Pathology impression: finding suggstive of missed abortion. Minimal separation of membranes noted.
Physician recommend to undergo D&C (dilation and curettage). What would be the actual action to be taken under such circumstances i.e.  D&C or wait for few weeks. Is such kind of sonography reports are always true.
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While waiting and re-scanning is probably safe, it is also unnecessary. Given the advanced size of the foetus, the lack of heartbeat is inconsistent with normal pregnancy and is diagnostic of nonviable pregnancy (missed abortion)
Diagnostic criteria for nonviable pregnancy early in the first trimester.  N Engl J Med. 2013 Oct 10;369(15):1443-51.
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Is there a place of leaving the placenta in-situ without removal or any other conservative measures
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And hysterectomy  , but it's not a conservative therapy
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In 1940 pudendal analgesia was quite popular to reduce the tonus of the pelvic floor muscles to avoid injuries. Does anybody know new studies about pudendal block and perineal protection at birth?
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Dear Peggy we are practicing pudendal  block for operative delivery only   
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I try to find an answer for a question which part of follicle have an importance role in initial primordial follicle. I think if we can stain mice oocyte  before they were born could partly answer this question. Do you know any chemical which can go through mother mice to prenatal mice ?
Thank you so much for your help.
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Thank you so much for your help. Even I could not apply your suggestions, however it is interesting to know utero-injection and Lei lei's teachnology. I could know we can order mutant mouse form Jackson's lab. Thank you so much and sorry for my late reply.
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Does anyone know a scale to study perception of women on childbirth experiences in hospital delivery, especially for developing country?
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The birth satisfaction scale revised - (BSS-R) produced by Hollins Martin
Caroline J. Hollins Martin, PhD, MPhil, BSc, PGCE, ADM, RM, RGN, MBPsS (Professor of Midwifery), Colin R. Martin, PhD, MBA, BSc, RN, YCAP, CPsychol, CSci, AFBPsS (Professor of Mental Health)  Development and psychometric properties of the Birth Satisfaction Scale-Revised (BSS-R) Midwifery 30 (2014) 610–619 
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we will be very grateful if we can get an approval for instruments related to male midwives for final year projects.   
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 You will need a sizeable group to say anything significant.   I do not think you will find one.   I would like to know what is interesting to you about this topic.    I do not think it warrants your time or efforts when there are so many important topics waiting to be researched in the field of midwifery.
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We`ve noticed that the number of abruptio placentae cases has dramatically increased in Ramadan (the month of fasting) in our hospital. Is there any study that links between them?
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Lakea et al (1997) found in a British cohort study that overweight and obesity in early adulthood appear to increase the risk of menstrual problems, hypertension in pregnancy increasing the risk of abruptio placentae. In a large cohort of singleton pregnancies Aliva et al. (2010) found that the risk of preeclampsia and eclampsia increased significantly with increasing BMI and decreasing age. Extremely obese teenagers were almost four times as likely to develop preeclampsia and eclampsia compared with nonobese women and teenagers were most at risk because of the combined effects of young age and obesity. In estimating risk factors for preeclampsia Baker and Haeri (2012) confirmed that maternal obesity and excessive gestational weight gain place the gravid teen at increased risk for preeclampsia. They suggested that the modifiable nature of these risk factors permits the possibility of intervention and prevention. 
A recent study study of the interrelationship between gestational weight gain, pre-pregnancy body mass index, race/ethnicity with hypertensive disorders during pregnancy showed that although there are some ethnic/racial variations, pregnant women who exceeded gestational weight gain recommendations are at increased risk of hypertensive disorders and risk of abruptio placentae (Masho et al 2016).
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during our students' clinical practice, they reported so many malpractices performed by midwives.
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Thank you, Dr. Lina, for the outstanding question
I do believe that improvement of midwife practice needs collaborative measures from all healthcare and policy-making stakeholders (including, government, JNMC, JNC, NGOs, Private and military sectors .., etc.), at the national level.  Regarding the malpractice, I think the role of the quality and patient safety department or team is very essential; still, patient's safety is everyone's responsibility.
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Horse riding women make use of their high pelvic floor muscle strength to explain their fear for vaginal birth. Legend or truth?
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Maybe in book by Kari, Bo et al 2015 Evidence based physiotherapy for pelvic floor muscles. Although I don't  see the connection because in horseback riding important muscle groups are thigh adductors, gluteals, guadriceps, core muscles...just my oppinion.
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Expectant management of preeclampsia with severe features?
Dear RG members. 
Do you consider that patients with severe pre-eclampsia could be put into a expectant management protocol? I mean: Do you think that expectant management of preeclampsia with severe features is a reasonable approach?
I appreciate your comments. 
Kind regards. 
Ramiro
PS: references feedback
Obstetrics
Perinatology
Preeclampsia
Maternal-fetal medicine 
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There are several issues to consider:
First and foremost,the health of the mother is paramount. If the severe feature are an indication of maternal CNS  dysfunction( Unremitting Headache, Visual disturbance) then temporization is unwise and potentially catastrophic.
IT is reasonable to stabilize with IV magnesium and IV anti-hypertensive agents and then reassess. IF after controlling the BP and seizure prophylaxis with Magnesium, the severe symptoms resolve, then  temporization may be considered BUT the risk to mom and fetus from an abrupt acceleration in condition is high and I would not consider it in a setting where emergent delivery  and experienced nursing are not available.
I have found that some patients with severe features are paradoxically volume overloaded( BNP is markedly elevated) and with careful use of Lasix and labetolol the elevated LFTs and low platelets have improved and normalized.  
So if treatment and optimization of the maternal condition is successful, temporization to get a full course of Betamethasone is warranted and likely to be beneficial.
Beyond 48 hrs, temporization is not going to benefit the fetus unless you are either at the limits of viability(22-25 weeks) OR unless you can get at least a week additional maturation in utero.
Remember the ONLY group that did worse in Liggins initial work on steroid for lung maturation was in the hypertensive, proteinuric, growth restricted fetus.
I agree with the other contributor that temporization in the face of severe features after 34 weeks is unwise and unlikely to benefit the baby, in fact, I usually deliver once a full course of steroids is on board after 32 weeks since the survival is over 95% at that GA.
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can anyone help me to get tool for quantitative study on obstetric violence
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By comparing total scores (better the score, better the sexual function) or by determining the rate of dysfunctional women in each group using the cutt-off of 26?
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Did you try to use my questionnaire "Libido Scorring System" in the literature. You can find my full text article free of charge and this questionnaire is very user friendly.
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supplements that affects the baby neurological development and their SNPs response
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Actually, for fetal neurocognitive development very important role plays mother psychoemotional status during pregnancy and how the mother is trying to help baby to develop while she or he is inside the uterus (music, reading books, touches, stimulation and etc.)   
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CS rates upto 80-90% are reported in certain areas. What are the contributing factors in developed and developing world? Should we regulate the practice? There is a changing trend nowadays with rising incidences of lower segment cesarian sections. What is the effect of this on women's health? Should we do so something to reduce the rising rate?
The complications and the cost burden in the health care system is huge.
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Midwifery led care is at least part of the solution.
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The tool will be used for evaluation of infants typically seen in Level 1 nursery.
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Ballard Scoring
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Which one would you prefer most of the time and why?
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I agree with Hamin. But if you take all these facts together it is better to have excellent training and expertize in laparosocopic appendectomy so the surgeon could have less preoperative strategic difficulties. When I started laparoscopic appendectomy it was easier for me to do open appendectomy. Now after more than 200 lap appendectomies I realise that it is more simple procedure technically (for me) and the easiest operations last 15 min and the patients recover ealier.
Therefore whatever the studies claim, my opinion is that laparoscopic appendectomy is better procedure in experienced hands.
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Need details of tocodynamometers from a mechanical engineer perspective.
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Speaking of external tocodynamometers, they are fragile equipment which should be protected from the coupling gel, usually used in close proximity due to the ultrasonic transducer that records the cardiac activity of the fetus  .
Those are tied on maternal uterine fundus where the uterine contractions are most prominantly detected but tend to change its position with maternal movement and contractions.
After placing an external tocodynamometer, one should reset it to the baseline level when there is no uterine contraction, otherwise there would be faulty readings.
whether it is piezoelectronic or a conventional pressure sensor, keep them dry and away from the gel.