Neurology - Science topic

Since 2020, we have developed a 5-pillar rehabilitation program at MediClin and examined the course of symptoms (13 scaled items on admission and discharge). Inpatients were recruited at 6 clinics with the departments of psychosomatics, neurology, pulmonology, internal medicine/cardiology or oncology. Accompanied by an expert board of all specialti...

This editorial provides a concise and updated overview of neuropsychiatry, emphasizing its definitional challenges and profound implications for education, training, research, and the integration of phenomenology and philosophy of mind. Neuropsychiatry, situated at the crossroads of neurology and psychiatry, grapples with complex definitional issu...

The Van Bogaert-Scherer-Epstein Syndrome (VBSES), also known as Van Bogaert-Scherer-Epstein Disease, is an exceedingly rare and enigmatic neurologic disorder characterized by a complex constellation of clinical symptoms and radiographic findings. Despite its scarcity, VBSES has been a subject of intrigue for medical professionals and researchers du...

Buku ini adalah kumpulan karya yang mendalam dan komprehensif dari berbagai penulis yang berfokus pada gizi dan penyakit kronis. Setiap bab menguraikan dengan cermat bagaimana aspek-aspek nutrisi dan pola makan memengaruhi perkembangan serta pengendalian berbagai penyakit kronis yang sering terjadi pada masyarakat. Dimulai dengan pembahasan tentang...

Background Spinal cord hemangioblastomas are rare benign and highly vascular tumors that develop either sporadically or as part of von Hippel–Lindau (VHL) disease. Generally, complete resection without significant neurologic deficit remains considerably challenging due to the risk of massive bleeding. The current study therefore aimed to describe e...

Aim We retrospectively analyse and review the results of microvascular decompression performed for trigeminal neuralgia. We also discuss the surgical nuances, complication avoidance and compare our results with other reported studies. Materials and methods This is a retrospective study in which the data of eighty-four patients who underwent microv...

Zusammenfassung Hintergrund In bis zu 43 % der Fälle entwickelt sich in Folge eines Schlaganfalls eine spastische Bewegungsstörung („spastic movement disorder“, SMD). Beim Vorliegen einer funktions- oder alltagsrelevanten SMD oder zur Vermeidung von Komplikationen wird die medikamentöse Behandlung einer fokalen, multifokalen und segmentalen spasti...

Introduction Acute necrotizing encephalopathy (ANE), a fatal subtype of infection‐triggered encephalopathy syndrome (ITES), can be triggered by many systemic infections. RANBP2 gene mutations were associated with recurrent ANE. Case presentation Here we report a 1‐year‐old girl with recurrent ITES and RANBP2 mutation. She was diagnosed with influe...

Eye tracking technology has emerged as a valuable tool in the field of medicine, offering a wide range of applications across various disciplines. This perspective article aims to provide a comprehensive overview of the diverse applications of eye tracking technology in medical practice. By summarizing the latest research findings, this article exp...

Intracranial compliance (ICC) holds significant potential in neuromonitoring, serving as a diagnostic tool and contributing to the evaluation of treatment outcomes. Despite its comprehensive concept, which allows consideration of changes in both volume and intracranial pressure (ICP), ICC monitoring has not yet established itself as a standard comp...

Background We investigated the predictors of poor neurological outcomes in extracorporeal cardiopulmonary resuscitation (ECPR) patients using machine learning (ML) approaches. Methods This study was a retrospective, single-center, observational study that included adult patients who underwent ECPR while hospitalized between January 2010 and Decemb...

Introduction and Problem Statement There is a need for structured EEG education opportunities to enhance neurology resident education. To address this need, the American Epilepsy Society (AES) supported the development and implementation of both synchronous and asynchronous EEG courses. Objectives To produce EEG curricula that enhance resident EEG...

SUMMARY Recreative use of laughing gas has been increasing in recent years. Because of the interaction of laughing gas with vitamin B12 metabolism, neurological symptoms can develop. These symptoms are polyneuropathy, myelopathy, or a combination of both. This article provides an overview of clinical symptoms due to the use of laughing gas, diagnos...

Neurofibromatosis type 1 (NF1) is an inherited disease caused by pathogenic variants of the NF1 gene present on chromosome 17 is an autosomal dominant disease of which occurs de novo. The cardinal signs of NF1 are cafe-au-lait spots and cutaneous neurofibromas. The ideal imaging is based on the realization of nuclear magnetic resonance imaging. The...

A 21-year-old woman woke up one morning with unusual symptoms. She found it challenging to move her lower limbs in bed, feeling a loss of control in them. When she tried to stand, she collapsed, unable to support her own weight. This weakness then spread to her upper limbs, and within four days, she became completely bedridden, unable to move, turn...

Research has shown myriad neurologic and mental health manifestations during the acute and subsequent stages of COVID-19 in people with HIV (PWH). This review summarizes the updates on central nervous system (CNS) outcomes following SARS-CoV-2 infection in PWH and highlight the existing knowledge gaps in this area. Studies leveraging electronic rec...

OBJECTIVES: Cannabis-based formulations have been used in neurology. To report, based on real-world experience, the clinical results of CBD /CBG pharmaceutical-grade formulations (PGF) in a series of cases of PD and DLB patients.

In this article, we explore the neurology behind Attention Deficit Hyperactivity Disorder (ADHD) and how it affects behaviour. By examining how the ADHD brain operates, we can gain valuable insight into how to teach physical education in a way that benefits those with ADHD. Additionally, understanding the experience of ADHD from a student's perspec...

Delayed neurologic sequelae (DNS) is a common complication in patients with carbon monoxide poisoning (COP). We aimed to investigate the association of the neutrophil-to-lymphocyte ratio (NLR) with the frequency of DNS in COP patients. A total of 371 COP patients were investigated in retrospective and prospective studies. A receiver operator curve...

Based on the seminal publications of Paul Broca and Carl Wernicke who established that aphasic syndromes (disorders of the verbal–linguistic aspects of communication) were predominantly the result of focal left-hemisphere lesions, “language” is traditionally viewed as a lateralized function of the left hemisphere. This, in turn, has diminished and...

This study evaluates the pro ciency of ChatGPT-4 across various medical specialties and assesses its potential as a study tool for medical students preparing for the United States Medical Licensing Examination (USMLE) Step 2 and related clinical subject exams. ChatGPT-4 answered board-level questions with 89% accuracy, but showcased signi cant disc...

Introdução: A epilepsia refratária representa um desafio na neurologia, afetando a qualidade de vida dos pacientes que não respondem às terapias farmacológicas convencionais. A Estimulação do Nervo Vago (ENV) surge como uma abordagem promissora. Metodologia: Esta revisão integrativa foi baseada em 29 estudos sobre a ENV no tratamento da epilepsia r...

A retrospective follow-up study was done, assessing regional practices in acute cervical reduction in hospitals in the Western Cape. The constitutional court ruled on the urgency in managing cervical dislocations, and our task is to ensure that medical treatment is optimized to comply with best medical practice and the apex court. A questionnaire w...

The interplay between nutrition and neurology has gained increasing recognition and various studies have emerged showing malnutrition and nutritional imbalances as a cause and result of certain neurological pathologies [...]

Peer review is an essential process in scientific research, ensuring the comprehensiveness, accuracy, and suitability of manuscripts for publication. Neurology education research differs from biomedical clinical research in several ways. These differences encompass specific paradigms, the use of theoretical frameworks, and different methodological...

Background Outpatient services in the UK, and in particular outpatient neurology services, are under considerable pressure with an ever-increasing gap between capacity and demand. To improve services, we first need to understand the current situation. This study aims to explore the patterns of appointment type seen in outpatient neurology, in order...

Diabetic ketoacidosis (DKA), a common onset modality of type 1 diabetes mellitus (T1DM), can lead, in rare instances, to the development of cerebral edema, which is the leading cause of mortality in T1DM. Aside from the identification of several demographic and clinical risk factors for cerebral edema, attention has also been drawn to the possible...

Spinal epidural hematoma is an uncommon but potentially devastating complication associated with various medical interventions. We present a case report of this rare neurological complication following a routine coronary angiography. A 69-year-old male with Aortic Stenosis presented for a scheduled coronary angiography to assess his cardiac status...

En un estudio descriptivo, retrospectivo se contabilizaron los pacientes con esclerosis múltiple atendidos en nuestro servicio de neurología desde el 2019. Se registraron variables demográficas, así como clínicas, de diagnóstico y tratamiento. En nuestro hospital el diagnostico de esclerosis múltiple se realiza de manera adecuada con base a la expl...

De los distintos tipos de epilepsia, de acuerdo con la clasificación de ILAE 2017 (5,6), la epilepsia focal es la más común representando el 61% de los casos en adultos (2,3). Las manifestaciones clínicas son variables y se relacionan con la zona epileptogénica, siendo la más frecuente la epilepsia del lóbulo temporal (1,4). El diagnóstico es clíni...

Introducción: el uso de la alimentación enteral en pacientes con demencia resulta un desafío ético-clínico. El objetivo de este artículo es exponer el proceso de validación de un cuestionario para conocer la opinión de los médicos al respecto y sus resultados preliminares. Metodología: se desarrolló un cuestionario anónimo para conocer la opinión d...

Objetivos: identificar las diferentes percepciones en cuanto a trastornos neurológicos funcionales por parte de especialistas de neurología (NRL), medicina física y rehabilitación (RHB), psiquiatría (PSQ) y medicina familiar y comunitaria (MFYC) Material y métodos: invitación a completar una encuesta vía google forms con 33 items (escala Likert, 5...

Abstracts Background Medical students and residents have been revealed to have extraordinary difficulties in managing patients with neurological complaints. However, specific information on Chinese trainees is scarce. Herein, we aimed to uncover the presence of, contributing factors for, and potential solutions to neurophobia among medical student...

The work called "LA ESTIMULACIÓN TRANSAURICULAR DEL NERVIO VAGO MODULA EL COMPONENTE P300 EN PACIENTES EN ESTADO DE MÍNIMA CONSCIENCIA" and carried out in collaboration between IRENEA and Universidad Loyola was presented at the XXI Jornadas de la Sociedad Española de Neurorrehablitación, held in Valencia on November 2, 2023. In this way, the neurop...

We present a case of a 70-year-old male who was brought to the hospital with altered mental status and was found to have 2 serious complications of cocaine use which are Cerebellar Hippocampal and Basal Nuclei Transient Edema with Restricted diffusion (CHANTER) syndrome and mesenteric ischemia. CHANTER syndrome is a recently described constellation...

El ensayo recoge las reflexiones sobre el desarrollo histórico y social de dos actividades inherentes al ser humano: la Ciencia y la Educación. La Ciencia, que surge como un nuevo tipo de visión sobre la realidad perceptible, que trasciende otro tipo de explicaciones posibles, entre ellas, las mitológicas o las subjetivas derivadas del sentido comú...

Objective The Center for Neurologic Study Bulbar Function Scale (CNS-BFS) was specifically designed as a self-report measure of bulbar function. The purpose of this research was to validate the Chinese translation of the CNS-BFSC as an effective measurement for the Chinese ALS population. Methods A total of 111 ALS patients were included in this s...

Since the early 1970s, the U.S. Food and Drug Administration (FDA) has received over 800 investigational new drug applications (INDs) for, and pre-INDs pertaining to, research of cannabis or cannabis-derived products. The current data show that applications for research of these products submitted by both academic researchers and commercial develop...

Pain is a complex emotional experience that still remains challenging to manage. Previous functional magnetic resonance imaging (fMRI) studies have associated pain with distributed patterns of brain activity (i.e., brain decoders), but it is still unclear whether these observations reflect causal mechanisms. To address this question, we devised a n...

Cognitive dysfunction (CD) is a neurologic complication of pediatric systemic lupus erythematosus (SLE) that remains poorly understood and understudied, despite the potential negative effects of CD on long-term socioeconomic status and quality of life. Data regarding the prevalence and risk factors for CD in pediatric SLE as well as the optimal scr...

An accurate and reliable neurological examination is pivotal in diagnosing patients with neurological and neurosurgical conditions. Despite the advancement of neuroscientific knowledge and the ever-progressing technologies and modalities that are being adopted to help achieve the challenge of accurate diagnosis, the neurologic examination is still...

In emergency neurology, numerous pathologies must be considered. Particularly in young people, even in the presence of clinical symptoms such as dizziness and headache, an anamnesis and clinical assessment must be carried out to identify whether there is an underlying neurological disease. In this category, in particular in the case of patients wit...

Background There is heterogeneity in depressive symptoms. However, latent classes of depressive symptoms and the transition and influences of these in young and middle-aged stroke patients are unclear. Objectives To identify the latent classes of depressive symptoms and their transition patterns over time and the influencing factors in young and m...

Jean-Martin Charcot, widely regarded as a leading founder of modern neurology, made substantial contributions to the understanding and characterization of numerous medical conditions. His initial focus was on internal medicine, later expanding to include neuropathology, general neurology, and eventually emerging fields such as neuropsychology and n...

Cartel que resume el Protocolo de intervención alimentaria- nutrimental en pacientes con ELA, atendidos por el Grupo de Apoyo Nutricional (GAN) del Instituto de Neurologia y Neurocirugia de La Habana, Cuba.

Objective Much has been discussed about gender diversity in all professional fields, particularly in medicine. Recent studies showing that there are fewer than ten female professionals in interventional neuroradiology (INR) in a continental country like Brazil, and less than thirty in all of Latin America, have prompted an investigation into the ca...

Background: Multiple sclerosis (MS) is a disease of the central nervous system characterized by inflammation, demyelination, and axonal degeneration. This study aimed to investigate the relationship between inflammatory indexes and MS disease activity and progression. Methods: A prospective cohort study was conducted at the Kocaeli University Neuro...

This paper first summarizes the definition of antisocial personality disorder (APD), and then explains the influence of antisocial personality on the patients themselves and the society as well as the etiological diagnosis and treatment methods. Finally, some suggestions for future research and intervention are given. The etiology and influence of...

Objectives Previous studies applying Sepsis-3 criteria to children were based on retrospective analyses of PICU cohorts. We aimed to compare organ dysfunction criteria in children with blood culture-proven sepsis, including emergency department, PICU, and ward patients, and to assess relevance of organ dysfunctions for mortality prediction. Design...

We report a case of a 9-year-old girl presenting with unilateral retinal arteriovenous malformation (AVM) with symptomatic macular edema. Over 5 years of follow-up includes optical coherence tomography (OCT), fundus photographs, and fluorescein angiography at baseline and at follow-up. Systemic and neurologic workup was completed and negative for i...

Objective To assess the functional disability level and identify associated factors in people after Ischemic Cerebral Vascular Accident. Methods A prospective cohort, carried out in a reference hospital in neurology with 224 people with ischemic stroke. Data collection took place between March and October 2019. Participants were followed up during...

O objetivo deste artigo é apresentar uma reflexão sobre as origens da musicoterapia e de como as evidências produzidas por estudos na área da neurociência cognitiva originaram as bases para uma mudança de paradigma da musicoterapia com o estabelecimento de uma nova abordagem, a musicoterapia neurológica (Neurologic Music Therapy, NMT). Sem a preten...

Penggunaan pestisida pada daerah pertanian merupakan salah satu faktor yang menyebabkan terjadinya gejala gangguan neurologis pada petani. Penelitian ini bertujuan untuk menganalisis dampak dari penggunaan pestisida dengan kejadian gangguan neurologis pada para petani berdasarkan dari berbagai artikel terkait yang dikumpulkan. Jenis penelitian ini...

To assess whether Roberts’ age-adjusted warfarin loading protocol is effective in Chinese patients and whether the SAMeTT2R2 score can predict international normalized ratio (INR) control. Roberts’ protocol for warfarin titration was applied to patients with non-valvular atrial fibrillation (NVAF) complicated with ischemic stroke at the Department...

Objetivo. Investigar os fatores clínico-neurológicos e a afasia em pacientes com AVCi maligno no hemisfério cerebral esquerdo, submetidos ou não a craniectomia descompressiva durante a internação hospitalar. Método. Estudo descritivo, retrospectivo, com base em análise de prontuário, de uma série de casos, de pacientes internados na Unidade de Acid...

The incidence of glioblastoma, the most common malignant primary brain tumour in adults, increases after the age of 40 and peaks in adults aged 75-84 years. Initial management involves maximising surgical resection while preserving neurologic function. IDH mutations and MGMT promoter methylation should be checked in tumour samples. Radiation and te...

This study determined the occurrence of cognitive impairment and mood disorders in out-of-hospital cardiac arrest (OHCA) survivors with good neurologic outcomes. We performed a retrospective, cross-sectional, single-center study with a total of 97 patients. We evaluated cognitive dysfunction via the Montreal Cognitive Assessment and Alzheimer’s dis...

It is important to predict the neurological prognoses of in-hospital cardiac arrest (IHCA) patients immediately after recovery of spontaneous circulation (ROSC) to make further critical management. The aim of this study was to confirm the usefulness of the Cardiac Arrest Survival Post-Resuscitation In-hospital (CASPRI) and Good Outcome Following At...

Electroencephalography (EEG) has been used for quite some time as a diagnostic technique in neurology. The goal of this publication is to serve as a resource for researchers interested in applying deep learning methods to EEG data. This paper proposes a unique Hybrid Machine-Deep Learning model that can learn and classify EEG signals on its own. Th...

Introdução: O Pronto Socorro é destinado a prestar assistência cujos agravos à saúde necessitam de atendimento imediato. Uma estratégia para atender as demandas desse serviço é a formação de equipes interdisciplinares. Objetivos: Analisar a atuação fisioterapêutica nos pacientes com emergências neurológicas internados, identificar os recursos fisio...

Aims: To evaluate fraction and size of financial conflicts of interest (COIs) between authors of Clinical Practice Guideline for Headache Disorders (CPGHD) and pharmaceutical companies in Japan. Methods: This retrospective analysis of personal payments data disclosed by pharmaceutical companies examined extents of financial relationships between al...

The potential of neuromorphic computing to bring about revolutionary advancements in multiple disciplines, such as artificial intelligence (AI), robotics, neurology, and cognitive science, is well recognised. This paper presents a comprehensive survey of current advancements in the use of machine learning techniques for the logical development of n...

Resumo A comunicação do septo atrial (CIA) representa, aproximadamente, de 6%-10% dos defeitos cardíacos congênitos, com incidência de 1 em 1.500 nascidos vivos.¹ Forame oval patente (FOP) é mais comum e está presente em mais de 20%-25% dos adultos.² Síndromes clínicas associadas a CIA e FOP são variáveis, com implicações abrangendo a medicina pedi...

Brain tumor segmentation from MRIs has been a continuing challenge for radiology and neurology specialists. Therefore, a reliable method that captures the growing and refined data in this regard, is much needed. Among many deep learning techniques having been proposed for medical image analysis, U-Net-based variants are found to the most used model...

Objectifs Les troubles de la déglutition sont fréquents à la phase aiguë d’un AVC et peuvent péjorer le pronostic vital et la qualité de vie des patients. Leur dépistage et leur traitement sont donc primordiaux. Les orthophonistes et les diététiciens collaborent de manière informelle depuis plusieurs années dans les services du pôle neurologie du C...

We provide an updated estimate of adult stroke event rates by age group, sex, and stroke type using Canadian administrative data. In the 2017–2018 fiscal year, there were an estimated 81,781 hospital or emergency department visits for stroke events in Canada, excluding Quebec. Our findings show that overall, the event rate of stroke is similar betw...

The canine distemper virus (CDV) causes a persistent infection within the central nervous system resulting in a progressive, multifocal demyelinating disease, and may also lead to gastrointestinal and/or respiratory signs. Due to the wide variety of clinical manifestations, determining the initial clinical manifestation of dogs with neurological CD...