Science topic

Negation - Science topic

The syntactic-semantic study of negation.
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1. Определение. Существует известная теорема, представляющая интервал в виде конечной или счетной суммы попарно непересекающихся интервалов. Сумма длин этих смежных интервалов равна длине интервала. Точки, не принадлежащие интервалам, являются точками соединения смежных интервалов или точками конденсации. Предположим, что существует сумма интервалов, что функция строго монотонна и имеет обратную величину на каждом из этих интервалов. В таком случае функция называется невырожденной. Если функция не имеет обратной величины для любой такой суммы интервалов ни на одном из своих интервалов или не является строго монотонной, то функция называется вырожденной. Остальные функции называются полувырожденными. Продолжение функции. Если возможно, продолжайте невырожденную функцию с помощью невырожденной функции до тех пор, пока она не станет невозможной. Замечание. Если функция непрерывна на интервалах, то достаточно требовать either strict monotonicity or invertibility. Example. A constant is a degenerate function. Theorem. The non-degenerate function has a finite non-zero derivative almost everywhere. Proof. By Lebesgue’s theorem, the non-degenerate function, as a strictly monotone function on intervals, has a finite derivative almost everywhere. Suppose it is equal to zero almost everywhere. By definition, it has an inverse. Then its derivative will also be monotone and not finite almost everywhere. This contradicts Lebesgue’s theorem. Conclusion. As the negation of a non-degenerate function, the degenerate function will almost everywhere be either non-differentiable, or its derivative
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Невырожденная функция аналитична? Всякую невырожденную функцию можно представить ряром фурье?
Is a non-degenerate function analytic? Can any non-degenerate function be represented by a Fourier series?
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Which is the most accurate/ usefull command in R for realizing a Necessity test: pofind() (with the option "nec") or superSubset()?
Which is the most common?
I understand that pofind() tests isolated ("independent") conditions and their negations; while superSubset() seeks configurations (i.e. combinations of conditions)....
I used to use superSubset()... but, perhaps for the two-step QCA process and for an ESA analysis... pofind() might be more useful...
Any insight?
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There should be no difference regarding accuracy, regardless of whether you use "pof", "pofind", or "superSubset" from the QCA package or "QCAfit" from the SetMethods package.
In terms of utility, this obviously depends on your research aims. As a standard function, I recommend working with QCAfit to investigate the potential necessity of all conditions in a single analytical step. Often, this is what you want to know - whether there are any conditions in your analysis that are in themselves consistently necessary.
The superSubset function is useful but it can also result in misleading conclusions, as when researchers try to make sense of necessary disjunctions with two or more elements. Of course, if there are theoretical expectations about specific SUIN conditions, then these could be tested with superSubset and/or with a specified argument in pof.
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recently, i am interest in the study on disocouse trap. as far as my knowlege goes, traditional discourse study focus on the exposure of power, ideaology, inequality,discrimination etc. few papers have discussed on the mechanism of setting up a trap of discourse so as to influence the discourse recipient to accept the special way of thinking and cognitive frame conciously and unconciously. when this speicial frame entrenched in the mind, recipients begin to negates its own position and viewpoint within a specific, limited and biased cognitive framework, thereby negating its own culture and self-worth.
with regard to this idea, i hope i can get more help from the international scholars.
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Discourse traps are a type of manipulation that can be used to influence the way people think and perceive things. They are often used to promote certain ideas or beliefs while suppressing others. The mechanism of setting up a trap of discourse is to influence the discourse recipient to accept a special way of thinking and cognitive frame consciously and unconsciously. When this special frame is entrenched in the mind, recipients begin to negate their own position and viewpoint within a specific, limited, and biased cognitive framework, thereby negating their own culture and self-worth .
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When I cite an author of a previous study in the discussion of data results because my research results corroborate or negate his or her study's findings, is it necessary, that i should already mentioned such study in my review of literature?
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Yes, you can cite a new study/author in the results and discussion portion of your study, even if such is not mentioned in your review of literature. However, it is important to explain why that particular study/author is relevant to your research, and how the findings may impact your results and conclusions.
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I am working with e.coli. I need help with interpretation of the results. I have worked with two E.coli strains. I did triplet technical replicates. I need to do statistical T-test.
Below is some of my datta:
Strain 1 0,407 0,544 0,639 Ave.: 0,53
Strain 2 0,384 0,515 0,34 Ave.: 0,413
Negativ control: 0,161 0,181 0,14 Ave.: 0,160667
Can someone help me with this. Please. There are several methods that are available to measure bacterial biofilm adherence. I was told to do a t-test beetween my average negatic control and a strain of E.coli.
PLEASE HELP
Thank you
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Hi Maryam, are these results of optical densities measuring at 600 nm?
Have you made calibrations of spectrophotometric readings vs. bacterial cell densities prior to the test? These data are necessary for any further statistical analysis.
I would like to recommend the following article:
Corte, L., Casagrande Pierantoni, D., Tascini, C., Roscini, L., & Cardinali, G. (2019). Biofilm specific activity: a measure to quantify microbial biofilm. Microorganisms, 7(3), 73.
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We love our conferences as we reconnect with colleagues, meet and greet new friends, visit new places, and enjoy the technical and social programs of the Conference.
It is indisputable that conferences these days are commercialized to the extent that African and Asian countries researchers can't afford attending, thus deepening the scientific and technological gap among researchers based on income and other factors. In my view, This is unethical. Fees system must be revised to address such serious problem.
Furthermore, the greediness extends beyond commercialization to ethics. It is becoming the norm to see the deadlines for paper submissions, acceptance dates, and camera ready dates are extended frequently to get more submissions. Such behaviour negates what we teach and preach about meeting deadline to our students and colleagues. I am puzzled to what I can say to my students when I am confronted by a request to extend the deadline for a Homework, an exam, or a Final.
It is about time that we adopt an ethical system where there is no deadline extensions and make our conferences feasible to attend for all researchers.
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It would be better the state's support.
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This may be a naive question, but why are the results of negated and positive outcomes not polar opposites of one another? There are different coverages and consistencies in the two outcome solutions - could that be reflective of the reason?
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By its very nature, unlike regression analysis, QCA is an asymmetric analysis. Therefore, it is to be expected that the coverage, number of configurations etc. to be different. For more details please see: Pappas, I. O., & Woodside, A. G. (2021). Fuzzy-set Qualitative Comparative Analysis (fsQCA): Guidelines for research practice in Information Systems and marketing. International Journal of Information Management, 58, 102310.
The article is open access on Science Direct.
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Hello,
I read some papers they used Pre-processing steps with text that will classify based on Sentiment Analysis.
My question is, can I use text Pre-processing techniques in the sentiment analysis classification, such as the Stop Words Removal and Stemming techniques? If can, it will cause Negations Words or Negation Prefix to be deleted, such as ( I am Not happy), will be (happy) after we use Stop Words Removal technique or (unlucky) will be (lucky) after we do Stemming process. That's mean the sentence that should classified into negative class will be classified into positive class. How to deal with that?
Thanks to answers in advance.
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Check out the following link, it might be useful for you:
Why is removing stop words not always a good idea
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Hi,
I am looking for a scale to measure technology rejection as a latent variable. Any pointer/suggestions will be appreciated!
[In the opinion of Gatignon and Robertson (1989), technology rejection is a distinct phenomenon and not merely a negation of its acceptance.]
Gatignon, H., & Robertson, T. S. (1989). Technology diffusion: An empirical test of competitive effects. Journal of Marketing, 53,
35-49.
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Thank you, Imran. I have seen these papers already. Their titles are misleading to the extent that the measure Acceptance and then talk about rejection without measuring rejection directly from respondents.
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I ran PCR in order to analyze a P-element excision on a mutant drosophila line. My results were not conclusive, however that is beside the point. I ran a temperature gradient in order to optimize the binding of my primers and negate the possibility of dimers forming. I noticed that I was getting different signal intensities for different DNA templates depending on the temperature. For example, I had no signal at all for my canton S wildtype at 57C and a strong signal for my excision line at the same temperature (57C). But then at 59C I got a strong signal for my canton S wildtype and an extremely weak signal for my excision line. I was just wondering what could account for this? Shouldn't the signals be relatively similar to each other even if they increase/decrease in intensity based off of the temperature? As in they should both have strong signal at 57C and then both have weak signal at 59C or vice versa (depending on the results of the temperature gradient). I added some pictures below of the gel from the 57C and the 59C samples that I ran.
PCR Parameters:
Primer concentration = 1uM
Template DNA = 200ng (found that 100ng gave too low signal)
Taq Polymerase mix = GoTaq Master Mix
Primer Tm = Forward 60.39C ; Reverse 60.81C
Cycles = 30
Annealing Time = (Temp gradient 57C, 58C, 59C, 60C, 62C) for 30 seconds
Denaturation Cycle = 94C for 30 seconds
Extension Cycle = 72C for 2:10 (target length 2169bp)
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At least your deletion line PCR worked pretty good now.
We use Promega GoTaqTM DNA polymerase a lot. My impression is that this polymerase is good for amplifying shorter bands. You are amplifying a band more than 2 kb (and from genomic DNA template, not even from plasmids). That is why your band is faint and sometimes it appears and sometimes doesn't. Promega did not mention what DNA size GoTaqTM DNA polymerase can amplify, but I think 2 kb PCR product probable is at the border line where you can see the product on a gel. Promega also sell GoTaqTM long DNA polymerase [1], which they advice to use for amplifying > 3kb genomic DNA. I bet the bands would show up nicely if you use a 'long-distance' or more robust DNA polymerase to amplify your control samples. Ask a small amount of robust DNA polymerase from other labs and try it out. Please do update us if you have result, I would very much like to see if this is the case.
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We are developing a test for ad-hoc (ad-hoc) and scalar implicatures (SI) and are showing 3 images (of similar nature) to the participants: image, image with 1 item, image with 2 items.
Eg. Plate with pasta, a plate with pasta and sauce, a plate with pasta, sauce and meatballs.
A question for an ad-hoc is: My pasta has meatballs, which is my pasta?
Q. for an SI is: My pasta has sauce or meatballs, which is my pasta? (pasta with sauce is the target item since we are testing pragmatic implicatures, where 'or' means 'not both'.
The item that causes many difficulties in making up questions is the image without any items, ie. plate with pasta. How do we phrase the question so that it elicits this image as a target response, without using too complex syntax?
Negation; "My plate has no sauce or meatballs", "My plate has only pasta, no sauce and no meatballs", seems like a complex structure to introduce as a counterbalance to the other type of items.
Has anyone tested something similar, without negation? We would be grateful for any kind of tips and hints.
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Could you just say: my plate has plain plasta?
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We are developing a test for ad-hoc (ad-hoc) and scalar implicatures (SI) and are showing 3 images (of similar nature) to the participants: image, image with 1 item, image with 2 items.
E.g. Plate with pasta, a plate with pasta and sauce, a plate with pasta, sauce and meatballs.
A question for an ad-hoc is: My pasta has meatballs, which is my pasta?
Q. for an SI is: My pasta has sauce or meatballs, which is my pasta? (pasta with sauce is the target item since we are testing pragmatic implicatures, where 'or' means 'not both'.)
The item that causes many difficulties in making up questions is the image without any items, ie. plate with pasta. How do we phrase the question so that it elicits this image as a target response, without using too complex syntax?
Negation; "My plate has no sauce or meatballs", "My plate has only pasta, no sauce and no meatballs", seems like a complex structure to introduce as a counterbalance to the other type of items.
Has anyone tested something similar, without negation? We would be grateful for any kind of tips and hints.
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Chris Dixon Thank you for the contribution! We thought about it and actually we will go with it for now, as 'empty' could be the ad hoc implicature. Only the plate then is the subject, not the pasta. But we will give 'empty' a shot!
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All the best
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I have seen studies that show that height is related to LV size and stroke volume, but not actual heart rate. My thought is that the larger stroke volume is negated by greater distance that blood needs to travel and larger blood volume that needs to be expelled from the ventricles. Please let me know, if I am wrong!
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Probably
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If dialectical logic is satisfied by below:
1) Defined in individual domain D, and its true-valued function is valued on closed interval [-1,+1];
2) For any individual variable a and b, and their true-valued function T(a), T(b), define three operators: conjunction operator /\, excuse me where restricted to can not use standard symbols and as same as below, disjunction operator \/, and negation operator #, make
T(a)/\T(b)=min{T(a),T(b)}
T(a)\/T(b)=max{T(a),T(b)}
#T(a)=#(v+,v+-1)=(1-v+,-v+)
3) If results oeprated by the three operators above is included in [-1,+1], then we call dialectical logic as self-completed.
Obviously dialectical logic is a Boolean-operated algebra.
Lemma1. Dialectical logic is self-completed.
Theorem: If a subset S of dialectical logic is self-completed, then this subset must be a Boolean-operated algebra.
Especially when this subset is valued on {0,1}, then it is just the Boolean algebra. Therefor we have the conclusion: Boolean algebra is a special case of dialectical logic.
Is the proof above true?
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to Ramkrishna Bhattachaarya,
Thanks for Ramkrishna Bhattacharya comments. As for your doubt, see my paper " Dialectical logic and Boolean algebra" and " Atomic proposition and 1-order predicate function for dialectical logic". Waiting for your grant instruction again, please.
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Hi Stuart,
I read your creep-ductility review with interest and would like to acknowledge the prominence you gave my work. However, I do believe there was some misunderstanding of my use of the term intrinsic ductility so I shall try and clarify.
1. I was unaware that the term is used to describe a construction on a creep to failure curve and also a Monkman-Grant analysis. I do not see how these measurements can be intrinsic when the specimen in both cases has to be subjected to a complex deformation path to failure before it can be measured. A term such as “effective ductility” or even “useful ductility” would be more appropriate. Intrinsic surely implies a current state measurement, like a physical property measurement, that makes no change and does no damage, or in the case of the short time stress relaxation test, minimal change to the specimen.
2. You indicate that the claim of detection of a stress-dependent ductility minimum is dubious because of the role played by time-dependent changes on the ductility minimum. My point is that there is a stress-dependent intrinsic ductility minimum in the original state. After exposure with time–dependent changes there is a new intrinsic state. However, in the analysis for T91steel, which you did not reference, which compared data for service exposed and reheat treated conditions, the change in the stress-dependence of the intrinsic ductility minimum was quite small even though the magnitude was significantly altered. Note also that the intrinsic ductility trends were consistent with elongation at failure trends in many heats of this steel (figure 10 in that paper and the text description) (1).
3. In summary, intrinsic ductility to me means an instantaneous or current snap-shot of the ductility capability. After service exposure a similar snap-shot will indicate any change in that capability. The conceptual difference from the traditional approach, including any arbitrary construction on a creep curve, I hope negates your calling the approach “dubious.”
4. Hart and other theoreticians, followed by many experimentalists made a big splash in the USA, notably in the 60s and 70s, and their work was my inspiration. I do not believe the work was followed in Europe. The SRT test as I developed it at high temperatures can be quite difficult to perform in a reproducible and stable way as I believe you had indicated to me. There are a few tests now reported in China and India that look promising.
I hope this helped to get us on the same wavelength,
Best regards,
David
1 David A Woodford, “Comparison of creep strength and intrinsic ductility for serviced and reheat treated T91 steel based on stress relaxation testing,” Mat. at High Temp., 34 (2), p.140-148.
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Intrinsic actually has a clear meaning: "belonging naturally, essential, inwardly, belonging to a thing by its very nature."
The current value of strain rate sensitivity, determined from a stress relaxation test, can be experimentally and theoretically related to intrinsic ductility. I later discovered that the term had previously been applied to a current comprehensive measure of the dislocation configuration.
In both cases the principle was that it was a measurement that did not require a test to failure. Any significant deformation would result in a new intrinsic ductility.
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For one of my recent article which is under peer-review, I got an impression (one of the reviewer explicitly mentioned the comment of the other reviewer ), that the two reviewers are able to/or allowed to read the comments of one another. Does it not negate the purpose of independent and unbiased review system? Or is it just a case where I have been ignorant or uninformed that such a practice exists?
If it does exist? Is this an ethical practice?
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It is highly desirable but unfortunately the predatory journals do not even send the MSS for review!
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I am trying to express mammalian protein in bacterial system. Protein Size 70kDa, vector backbone pET28a+. I received the gene in pUC backbone, when transformed in DH5a, showed clonal variation. Upon checking, correct clone was selected and assumed that after ligation, there might not be any such difference but to my surprise, there also i am getting clonal variation. I have taken negative controls like vector, insert and competent cells to negate any extraction and handling errors. Would appreciate suggestions and method to understand this problem.
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Even if you see a clean PCR product, it can be that unespecific amplifications are cloned in your plasmid giving you that variability. Probably you have done it but cuttinig the DNA band out of the gel is safer. pET28a is a stable plasmid, I would not think that something is wrong with your plasmid but your cloned fragment.
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As locations on a dimension, are you considering:
Hyperbole, tautology, meiosis, [ZERO], irony {sarcasm]?
Do we have a term for the zero in this dimension? Should we take sarcasm as "biting" irony, that is as more extreme, as hyperbolic? Is simple negation a zero on the scale? Or does irony require a step further on the scale?
John Kennedy
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Imagine there's a rally and 100 people show up.
> Thousands join the rally (Hyperbole)
> Dozens of people at the rally (Meiosis)
> Not exactly hundreds at the rally (Litotes)
> Not a soul a the rally (Zero?)
> I didn't know you could fit thousands in an auditorium (Hyperbolic irony)
> That wasn't a world-shaking crowd (Litotic irony)
> More people show up at my birthday party (Meiotic irony)
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Laws of dialectics describe evolution of knowledge as well as development of things and nature. These laws are mainly three given by:
  1. The law of the unity and conflict of opposites.
  2. The law of the passage of quantitative changes into qualitative changes.
  3. The law of the negation of the negation.
However, how these laws are applied to conduct new research, to develop new solutions represents a challenging task. Please try to describe your experience on applying these laws to conform or arrive to novel and useful scientific or technical solutions.
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Dear Hein Retter thanks for your response. In may case what motivates these topics is related to the following questions:
1. Is there any recommendation or experience to conduct research based on laws of dialectics?
2. It is possible to stablish a proper path or research trayectory in advance by the laws of dialectics?
3. It is possible to reduce uncertinty on selecting the proper hyphotesis by using a priori the law of dialectics?
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Hi ,
Suppose an aperture is illuminated by laser ,and i'm interested in its negative by optics means.
I need to maintain the waveform coherence of the negative image to be processed at Fourier optics.
Does anyone has a way without using interferometer ?
for example:
input image                  output image:
1 1 1                               0 0 0
1 0 1                               0 1 0
1 1 1                               0 0 0 
I thought of this setup:
pass the laser beam through beam splitter.
one of the beam passes through the aperture and then through a waveplate of half wavelength.
Then the two beams are recombined at beam combiner.
This way the waveforms are substracted.
Thank you 
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Thank you for the answer. I'll examine this. Others tools available for simulations? Matlab? Python? 
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Qualitative studies, particularly doctoral theses are declared incoherent in case a researcher use methodology inherently lying in other paradigm as different paradigms have different assumptions about the social world and the methodologies to know it. My question is then do mixing methods across paradigms (pragmatism) not negate the basic purpose of the paradigms? How can a social reality be simultaneously seen from realist (or its variants) and idealist (or its variants) views?
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I think there is a major problem with statements such as: "Research objectives which require to mix methods from multiple paradigms should be explicity defined and justified on the nature of social reality." This is the assumption that paradigms from the philosophy of knowledge are directly connected to methods in the social sciences. 
Although the mistaken assumption that methods are attached to paradigms is quite common, even a quick reading of such leading paradigm proponents as Lincoln & Guba will show they are explicit that their discussion is not about methods. So the initial issue of, "do mixing methods across paradigms (pragmatism) not negate the basic purpose of the paradigms" is not an issue because this is not what the paradigm wars were ever about.
Also, the statement about pragmatism as consisting of mixing methods tends to get things backward. Pragmatism is not a reason for mixing methods. Instead, it is an entirely separate paradigm within the philosophy of knowledge, and it is especially notable because it rejects the distinction between realism and interpretivism (constructivism) as a false dichotomy. Researchers within the field of mixed methods have thus found pragmatism to be a useful escape from the unanswerable debate between realism and interpretivism -- which is exactly what pragmatist philosophers such as William James and John Dewey intended.
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In quantum physics,  the no-communication theorem states that it is not possible to transmit information from one observer to another observer, whether entangled or not, by making a measurement of a subsystem of a total state, common to both observers.
Most people think that the theorem is important because it limits quantum entanglement, that separated events cannot be correlated in any way to lead to the possibility of communication. 
However, the double-slit experiment [1] says that what one observer does (e.g. turn on a detector) influences what is detected at the other observer (e.g. the electron did not pass here).
What is your reference or position on this question, could the double-slit experiment be used to negate the no-communication theorem?
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Hello all,
Thank you for your participation. As you know, Jacques can ask his own question in RG. This question is not that, it's whether an observer's own decision about the use of a detector may lead to communication to another (spatially separated, independent) observer, an observer that is just not "downstream" from the former one  -- but it is peer. It's not the place to use words that are unacceptable by a scientific study, but to build, to mine the gold of truth using fair, polite, cogent public discussions.
Jacques, if you do not agree with this, you can continue to observe, or even join in, albeit in fair terms. Otherwise, life itself may become harder, even to all of us, life is a school.
Cheers, Ed Gerck 
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So I'm making silicone pads through spin-coating onto wafers, but I am not getting a uniform thickness from center to edge. I've tried using more material to cover the entirety of the surface before spinning so as to negate force differences. I've also tried varying spin speed. Any suggestions?
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James Hanson pretty much said it all except two things....
1) Be sure to thoroughly clean your substrate. The solution will not "wet" a poorly cleaned substrate resulting in bad film quality.
2) When you say center to edge you must remember that the very edge will not have the same properties as the the rest of the film since the last few microns can suffer from instabilities.
Good Luck.
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My requirement is user  feedbacks on restaurant data  and determining if they are positive or negative about a subject. I am taking the approach outlined below, but I keep reading NLP may be of use here. All that I have read has pointed at NLP detecting opinion from fact, which I don't think would matter much in my case. I'm wondering two things:
1) Why wouldn't my algorithm work and/or how can I improve it? ( I know sarcasm would probably be a pitfall, but again I don't see that occurring much in the type of news we will be getting)
2) How would NLP help, why should I use it?
My algorithmic approach (I have dictionaries of positive, negative, and negation words):
1) Count number of positive and negative words in article
2) If a negation word is found with 2 or 3 words of the positive or negative word, (ie: NOT the best) negate the score.
3) Multiply the scores by weights that have been manually assigned to each word. (1.0 to start)
4) Add up the totals for positive and negative to get the sentiment score.
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First of all I am not a subject expert in NLP just involved in couple of NLP related works. I feel if you use Ontology it will work better. first populate Ontology classes and relations in Restaurant domain. While taking Positive and Negative words consider ontological relevance and weightage scores along with. may improve accuracy of your algorithm.
Hope it helps.
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Decoupling GDP from resource use through resource and efficiency revolution has become crucial mantra of our time to ensure absolute resource consumption level within ecological limits. However, it is generally argued that the rebound effect may occur if energy efficiency (EE) improvements enable other resource-intensive activities to take place, thereby negating any saving or efficiency gain. This is because  EE gain lowers real price of energy & thus induces energy use due to combination of substitution effect (making energy cheaper than other inputs) &  income effect (economic growth pulls up energy use).  Some other argue that even if EE does not lead to absolute reduction in energy use in all cases it improves access to energy service by lowering their effective cost.
Are there any empirical evidence from any countries showing the magnitude to various rebound effects and the extent to which they prevent consumption from staying within ecological limits?
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Bikash, I think that the previous responses answer your question accurately.  We refer to numerous studies in the literature in my most recent paper.  Our measurements in a real world setting show that EE did actually reduce energy use.  Energy use has also declined across the UK since around 2005.  Energy prices fluctuate wildly and I think that rather than focus on monetary savings due to EE it is better to focus on the overall carbon impacts of differing lifestyles - for eample the amount of air travel or high mileage car use.  These are much more significant than relatively minor changes to domestic EE.  Focus on EE and "rebound" or "backfire" is in my view not particularly helpful.  In my view the key issue is the degree that our energy related technologies overall become less carbon intensive within a similar apparent consumption envelope.  And I agree that GDP itself is a deeply flawed measure.
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I have a research project with seven predictor variables that have relatively high correlations with each other. Also, the actual multicollinearity statistics are very poor.
Unfortunately, qualitative analyses led us to these quantitive tests, so removing variables is not ideal. Please let me know if you know of any methods to negate this issue.
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Dear Daniele, let me ask you - what is the final objective of your project? Will you focus on outcome (prediction) or on process itself (for example studying impact of individual variables)? Because for prediction, multicollinearity does not have to be such big issue. A nice comment has been recently done in this study - https://www.toi.no/getfile.php/Publikasjoner/T%C3%98I%20rapporter/2015/1403-2015/1403-2015-elektronisk.pdf (chapter 13 - Don’t worry about multicollinearity).
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Machine Learning in negation and speculation detection ...
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Thank you all so much!!! 
I really appreciate the valuable help provided by the research comunity. Thank you Sascha!
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I came across such a claim in the literature of Chinese grammar.
Someone suggests that a Chinese equivalent of "in vain" is a negator of a presupposition that doing something will be rewarded. I don't know if the concept of "presupposition negator" makes any sense.
I would also like to know if there are works deliberating on the issue of what is/is not a presupposition trigger, not for the very straightforward presuppositions, but for those very complicated ones.
I mean those kind of background presuppositions. It seems to me that they are not presuppositions at all. But what are they? The starting example is "in vain".
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I totally agree with Glenn that in "John talked in vain" "in vain" does not cancel the presupposition that "John did talk" but we seem to infer from it that his speech fell on deaf ears. The same holds for the second example, where the goal of teaching (i.e. learning) did not obtain, but the presupposition that teaching did take place is there. However, in terms of this "presupposition negator" I am thinking of complement clauses of negative implicative verbs such as fail, remember, manage, forget, refuse, stop, pretend, and prevent, which all cancel the presupposition such as in:
Monica failed to attend the party (presupposes that Monica did not attend).
Monica refused to attend the party (presupposes that Monica did not attend).
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Do you know about some research? What would you recommend to study in regards to this relationship?
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Perhaps you like the attached article