Nanoparticle Synthesis - Science topic

Good evening everyone

I am working on green synthesis of selenium nanoparticles from leaf extract. The research article mentions that during selenium nanoparticle synthesis, ascorbic acid should be used as a catalyst. so why there is a need to use a catalyst?., and what is the best drying method for synthesized selenium nanoparticles?

Does anyone know?

1. Do biosurfactants still have the capacity to reduce surface tension when used as nanoparticle stabilizing agents?

2. When nanoparticles are produced mediated by biosurfactants, are they in the form of liposomes or micelles? by considering several references using the Riverse microemulsion synthesis procedure (water to oil)

I want to study the opto-structural and magnetic property by XRD,XPS and SEM analysis.

I want to prepare a solution of TiCl4 in Millipore water for the Titanium nanoparticle synthesis.

Hi all,

I am currently working on a microfluidic system where two fluids are introduced with adjustable flow rates into a mixing chamber. The purpose of this system is to facilitate nanoparticle synthesis. The construction of the microfluidic part of my system is completed, and I have a working model of the mixing process that does not include the synthesis aspect.

My inquiry centers around whether anyone has expertise in modeling the synthesis that occurs within such a system. Specifically, I am interested in any type of synthesis modeling as my primary goal is to ascertain the feasibility of simulating this process. Additionally, I am curious to learn which physical principles I should take into account when developing my model.

Any guidance or references to relevant literature would be greatly appreciated.

Thank you in advance for your time and assistance.

I am working on Chitosan nanoparticle synthesis and characterization. But I can see the nanoparticle aggregate after some time and hence the respective increase in particle size. How to increase the stability, please suggest.

After nanoparticle synthesis using plant source, we need to take the absorbance data to see the high peak. My question is -

Do I need the blank to get the absorbance data or I can get the absorbance data by keeping the nanoparticle solution in different wavelength?

I would like to synthesize SnO2 nanoparticles from SnCl4. Having problem with ppt washing. Precipitates washing away during cleaning. Please help with expert opinion or suggestions.

I made HSA nanoparticles by desolvation method. I took 180mg HSA and dissovled it in 4mL of milliQ water (45mg/ml) and then in the protien solution added 2.5mL of ethanol dropwise, then these nanoparticles were stablized by adding EDC (5mg in 0.5ml of milliQ). The solution was left for 3hrs for nanoparticles synthesis under constant stirring at 1250. The nanoparticles size was checked by zeta sizer and the size found to be 64nm. Then i tried to settle down the nanoparticle at 13000rpm for 10 min but I'm not getting pellet. Further I also tried to increase the cetrifugation speed and time still i did not get the pellet. Any suggetion about this query would be appreciated.

I found some issues trying to clean a micrometric channel made of PDMS. This channel is part of a chip which has been used as a droplet generator before and it's 50 micrometers wide and 25 micrometers deep. Now I use it for Nanoparticle synthesis. I tried using a syringe pump loaded with DI water and it leaves clots of NPs inside of channel, making the chip useless. Do you have any idea which material (Like HCl solution) I should use and how to use it (Ultrasound or pumping)?

Thanks

Dear beloved scientist.

I have a question regarding ZIF-8 Nanoparticles synthesis. I used Zn(NO3)2.6 H2O as Zn2+ precursor and 1,2-dimethylimidazole (1,2-Dmim) as the Mim source with molar ratio of 1:4. Then they were solved in 50 ml methanol and stirred for 24 h at room temperature. But, after 2- 3 hours, there is no color change in the reaction solution. I use this journal as my reference for synthesis ( ). Is it normal to have no color change after several hours? How the color of the solution of the success reaction of ZIF-8 NPs? Because it's my first time to do this synthesis. Do you have any opinion that can improve my method? Your opinion regarding this matter is very welcomed.

Thank you.

What are the biggest technological challenges in the production of core-shell nanomaterials?

Can you please tell your experience and/or give comments on morphology control, synthesis precision, stability and durability, economic viability, etc.

Dear researchers,

Is there any method or device like Amicon 0.5ml ultracentrifuge (Its highest cut-off is 100kDa and not good for my purpose) that I could purify my small amount of volume nanoparticles that are conjugated with high MW polymer (more than 400kDa)? I tried 0.5ml ultracentrifugation of 135k*g for 1 hrs but the pellets are not obvious based on a small initial amount of lipid particles that contain nucleic acid.

I am currently working on chitosan nanoparticles synthesis by ionic gelation method. I dissolve chitosan in 1% acetic acid (to make a solution of 1mg/ml) Regarding that I have some queries:

I'm at the end of my preliminary experiment for the synthesis of Hap, but I noticed traces of black ink in my dried hydroxyapatite, I tried to search at which temperature the component in black ink decomposes, but I'm still quite unsure.

Best Regards

-Flynne

e.g: nickel nanoparticles by hydrazine

Explanation.

PVP behaves as a capping agent in the synthesis of Ag nanoparticles.

For Example, 1 At% / 1 Wt% / 1 mol% of Zn doped in TiO2.

In order to synthesize silver nanoparticles with specific shapes such as triangular or decahedron, we usually add capping agents such as PVP or citrate to the solution. for higher concentration solution the amount of these organic compounds should be increased inevitably. After drying one droplet of the final solution, thick layer of organic materials covers the nanoparticles (as shown in the attached figure).

I have seen that in many papers people suggest using "dialysis bag" or "centrifuge tube with filtration membrane" but both of these techniques may destroy unstable nanoparticles (specially triangular shaped N.Ps). Do you have any suggestion for getting rid of any organic materials form the final solution with out sacrificing the nanoparticles?

I synthesize mesoporous silica nanoparticles, then the glassware has a white residue in its walls, so how can I eliminate this residue?

Looking forward to the dynamics of plasma - electric field distribution.

and evaluating the forces in plasma - PCVD- nano particle distribution.

I used an initiator for polymerization of a monomer, is it possible to use the same initiator for the same monomer to synthesize polymer nanoparticles?

regards

Hello, I'm working on interactions of some inorganic metals/compounds with some protein of interest. Here the ligand are in nanoparticle form. So as for ligand preparation for docking these need to be in nanoscale range, is there any procedure for preparing it ?

Please suggest some user friendly software other than Vesta if possible!

Thanks in advance.

Regards,

Vinay

The fate of nanodrugs / nanoparticles in vivo draws a lot of attention, and many studies label fluorescent of nanodrugs / nanoparticles in order to disclose their distribution in vivo.

- What are its advantages and disadvantages ?

- Is it a reliable tool ?

Please treatment would you recommend for my mortar and pestle as well as the magnetic stirrer that got stained (with black) after using them for magnetic nanoparticles synthesis?

Thank you

I am currently working on Janus nanoparticles synthesis. I have been tried to wash the colloidosomes with chloroform several times by stirring and centrifugation, and even tried chloroform followed by recrystallization in cold methanol, unfortunately I could not obtain the Janus nanoparticles meanwhile the SEM pictures clearly show the nanoparticles onto the wax surface. Could someone providing me with any suggestions?

Kind regards,

Dear Everyone. I am trying to do the high yield synthesis from ascorbate and copper salt, according to the similar procedures from the literature (0.18M copper ions) I now tried PVA up to 2%, Tween 20 up to 10%, both, none, dropwise addition of ascorbate, burst addition of ascorbate, nitrogen, air atmosphere, temperatures 50, 60, 90 centigrade. I followed a couple of similar syntheses from the literature, nothing works. All the time instead of suspension I get a salmon-colored precipitate that for sure is not a dozen nanometer copper. What do I do wrong?

Thanks a lot for all the hints

In nanoparticles synthesis, reducing agents change metal into its zero oxidation state,which form cluster with other atoms and then coated with capping agent, why necessary to change metal into zero oxidation states, which force responsible to form clusters?

I am preparing nano ferrites by using microwave hydrothermal method to get the precipitation. We are adding NaOH with maintaining pH, I would like to ask what is the main role of pH?

Does it affect particle size of material? How?

Hello!

Ive never made micelles before, but I gave it a go today and now I have some questions. I am generating thin films using my polymer solubilized in chloroform, evaporating in a rotovap, and then resolubilizing in water followed by 30 min of sonication. I currently (very sadly) do not have access to DLS, I am thinking about getting the Lens3 from Tosoh and analyzing my particles using MALS very soon, until then I dont have any physical characterization assays setup. As a very general description of my molecule, I have conjugated a hydrophobic molecule onto a cationic/hydrophilic polymer

1. What size flask is appropriate for 2mgs of polymer? I tried 100mL, 250mL, and 1L. the 1L sized flask was a bit cumbersome to do the hydration in and the thin films from the 100 or 250 mL flask dont look that thin

2. How quickly do I add water to the solution? Dropwise or all at once?

3. Should i start sonicating the micelles as they rehydrate? Should I rehydrate and then wait and then sonicate?

4. Does adding salt to micelles during hydration or after hydration change particle size?

5. How stable are cationic micelles in general in water or buffer? Hours? Days Weeks? The paper im referencing has no stability data

6. Are there any solvents that are not acceptable for forming thin films/micelles? Variants of my polymer are soluble in ethanol but not in chloroform so can I use ethanol instead?

Im still going through all the literature to find answers to some of my more basic questions, but any useful papers you can recommend would be very much appreciated and a big time saver for me!

Which one is better?

At the first 1 g of HIPS polystyrene thermoplastic polymer was mixed with 10 cc of toluene solution for 1 hour and a half using a magnetic stirrer.

The resulting solution was mixed with 0.2 g of hydrophobic sio2 nanoparticles for 1 hour using a magnetic stirrer.

The solution obtained from the previous step was dispersed under ultrasonic bath ( 5 x 100 second cycles )

Then polydimethylsiloxane Silgar 184 was mixed in a ratio of 10: 1 with the solution obtained in the previous step for 30 minutes.

And then 500 seconds (5x100) again with ultrasonic.

The resulting solution was immersed twice as a coating on aluminum substrates, wood and glass slides.

After 24 hours, the coating was dried in the oven for 30 minutes at 100 degrees

The contact angle of the water drop was 118 degrees (without polydimethylsiloxane) if the contact angle with polydimethylsiloxane was expected to increase but decreased to 100 degrees.

Is there a mistake in the protocol?

Is there a problem with the time it takes to put it in the oven?

I have synthesized Magnetite Nanoparticles using Cyanobacterial Polysaccharide crystals and as the nanoparticles are not dissolved, I am not able to proceed with my work . Can any one help me in dissolving the MNPs.

nanoparticles synthesis and applications

Stocks of KHP near me ran out due to pandemic and it would take months to arrive if I order overseas. Is it really necessary to standardize them in this type of research? If not, can you please share me an article about it? i would gladly accept your answers

How the the defects like oxygen vacancies and structure distortion from its original, un saturated bonds. particularly in Ferrites (Ni, Zn ferrites) can effect lattice parameter?.

Hello everyone,

I hope you are doing well in this pandemic.

Currently, I am doing PhD in powder metallurgy. I am in the stage of submission, so looking for a postdoc. But, I am a little bit confused about the selection of the topic. I have worked on metal matrix composites, polymer matrix composites, and nanoparticles synthesis during my M.Tech and PhD. I have published papers in all three areas. Can anyone suggest which topic will be better for me (in terms of future scope, novelty)? I am looking for your valuable suggestions.

Thank you

It is hard to find any reference related with gold nanoparticle synthesis using plant extracts that were extracted using ethanol solvent and has weight concentration (m/v) as one of its optimizing parameters aside from other parameters such as temperature, pH, HAuCl4 concentration (mM). I need the weight concentrations parameter for me to refer to and use in my current work for a research project in Masters's.

Hi community,

I am currently looking into strategies to reliably and robustly generate, preferably in the direction of minimum 50 mg total metal quantity per batch, colloidal bimetallic Janus NPs. While I have come across a variety of options lately (see the references at the end of the question description), there may be some expert advice out there that could point me at important considerations that I have previously not thought of (so I am more asking for directions, rather than a chewed out protocol).

I decided on a simple starting point and created spherical Au NPs around 10-20 nm in diameter as a seed (and reference) material for further ' bimetallization'. These were prepared by the established citrate-reduction method. Then I would like to perform a second step in which I grow the metal of lesser nobility on the Au seed surface. For a metal like Ag, that step seems rather simple as the metal precursor is added with additional reductant and stirred/refluxed for minutes to an hour to complete the process (e.g. [1] or [2]). In combination with Cu, there are also several reported methods (e.g. [3] or [4]), though these two in particular use inert atmosphere to effect the synthesis, which I think should not have to be a necessity to prepare AuCu NPs in general (and would make reproducibility labile I think). Metals such as Ni, Co, and even Fe can be made into a Janus NP with Au (e.g. [5] and [6]). However, I am avoiding a one-pot method to co-reduce the noble and non-noble metal concomitantly, as I would like to exert more control on i) NP size by first establishing the seed size, and ii) its growth mode on the seed by varying e.g. ligand/surfactant concentration (though this reasoning may not be entirely grounded for going with a two-step process).

Any suggestions would be helpful.

References:

[1]

[2]

[3]

[4]

[5]

[6]

I have been synthesizing albumin nanoparticles for about 5 months. But for the last 1 month, I have been having trouble with nanoparticle synthesis. I can precipitate nanoparticles in 1 of the 5-6 experiments I have done. Suspecting that the BSA was broken, we ordered a new one and the result did not change. What could be the problem?

hi I'm currently trying to synthesize nanoparticles SnO2 by co-precipitation method. From the XRD result, it appears that SnO2 have been detected. But when I tried to check the optical band gap with tauc plot method, the optical band gap was far below 3.6 eV (which is the bulk SnO2 optical band gap). Is there any explanation what causes this? (the absorption curve in the attachment)

In nanoparticles synthesis the use of hydroalcohol solvent in soxhlet extraction is correct or not... and I need article reference for this.

I have synthesized NiO nano particle. And they shown change in properties when we goes from bulk to nano regime. In bulk regime shown transition metal oxide but in nano regime shown semiconductor. Why this properties will be changed? I want to know the exact reason. Please explain it in details.

In one reaction, cyanamide and 1,6-diaminohexan were used to link one compound with the NH2 functional group and the other with the COOH. I do not understand exactly the role and function of cyanamide and 1,6-diaminohexan. Can anyone help me?

I tried to synthesize samarium nanoparticles using curcumin. I used samarium nitrate as a processor and curcumin as a reducing agent. I put the solution of samarium nitrate and curcumin on a magnetic stirrer at 80 ° C for 4 hours. But after centrifugation, I got a small amount of precipitate and could not dry it.

I also put samarium nitrate and curcumin solution in an incubator shaker overnight. No precipitate is formed after centrifugation.

Should I use another substance (eg samarium chloride or samarium oxide) instead of samarium nitrate?

volume ratio of Nickel acetate and Tannic acid?

I have heard, that larger the ligands, more better the core shell structures due to the packing of the which in turn results in a decrease in the density of ligands on the surface of the NP.

Is is true? How branching affects the formation of core shell?

I am trying to find the reduction potential of long chain primary alkylamines, in particulcar Dodecylamine and Oleylamine.

What it could be?

Hello,

During the synthesis of nanoparticles, many at times a particular pH value is optimum for that process.

I am confused as to whether the pH needs to be adjusted during the reaction while mixing the precursors, or after mixing the precursors (followed by continued stirring for a certain period of time).

Does it depend on the reaction or is there a preferred way?

I am asking this as I have found both of the above mentioned approaches in papers.

For example for the synthesis of covellite copper sulide (CuS) nanoparticles:

Thank you

They need to be agglomerate free. They can be in any aqueous or alcohol solution. These are commercially available, but the vendors generally don't tell you how it is done.

Please i still want more clarity on synthesis of silver nanoparticles. I tried different parameters like changing concentration of plant extract, for silver nitrate and so on. I observed color change from green to dark brown but yet there is nor SPR at 420. My peak is now at 345. Is it possible that my plant extract cannot reduce silver nitrate or what is the justification? Or maybe the problem could be silver nitrate?

I have encountered some studies doing this through some calculations involving FWHM values of PL bands but I couldn't figure that out. I am calculating radii by using the effective mass approximation. EMA predicts radii through bandgap energy, therefore, the output is unrealistically precise and doesn't have any error function. One of the reviewers especially asked for the size distribution calculation from the FWHM value of the PL band.

Hello, I am creating Nickel nanoparticles and I am always creating a black precipitate. I either use NiCl2/NiSO4 with citrate or PEG in water/Ethanol. My reducing agent is NaBH4. No matter what combination or slight molar changes I do, I always get a black precipitates forming. Sometimes they're a fine mist that settles after or large chunks. If anyone has any experience with this, please let me know. Thank you in advance.

I recently found a publication that states extruded nanoparticles of roughly 120nm with +/- 1.21nm. This converts to a PDI of roughly 0.00011. Is this reliable? Or even possible?

I have seen 'n' of papers talking about deposition of semiconductor shells on metal surfaces. However, there is a very limited literature about the deposition of metal shells on semiconductor nanocrystal. Why is it hard to achieve a full or complete shell on semiconductor?

Please pour your suggestions.

I have chemically synthesized silver nanoparticle to combat microbes on wound site. I have used many methods of synthesis, but I found minimal field of silver NP product.I am getting whitish precipitate if I target high yield using sodium borohydride and ethanol.

Is there any method that give high yield silver nanoparticles. I would also like to know the post processing steps after AgNP synthesis(drying, finding collidal NP concentration,resuspension), as many articles won't report those steps.

hello

I am trying to synthesize CS NPs by ionic gelation method using TPP but I can not get PDI under 0.3. what am I doing wrong? here is my method till here.

my sizes are good and under 300 nm mostly. even though I use filtering (0.22 nm filters) and sonication and centrifuge. and I dilute my sample before testing for getting a more transparent solution.

the Conc of my LMW CS is 1 mg/ml (solvent 10 cc acid acetic 0.1 %) and Conc of TPP is 0.5 mg/ml (solvent 10 cc deionized water).

I let the CS to dissolve overnight on the heater stirrer with temperature 30-40 C. the next dey I have a transparent CS solution. after dissolving the TPP by stirring for about 10-30 min at RT, I add TPP dropwise to the stirring CS solution. I used syringes sometimes but the rate of adding was too rapid I think and by using burette I could control the rate but I think it was still high and with bigger drops. all of TPP solution will drop in about 4 min into the CS solution. how should I add TPP? with such rate and what equipment? after adding TPP, I let the solution to stirr for 1 h in RT in 7000 rpm trying to have a balanced stirr. and then I centrifuge for 5 min, 6000 rpm, after that filtration and sonication for about 2 min.

so now here is my QAs:

1. is there a special environment to work in to be sure that I am avoiding external Contaminations?

2.how should I add TPP? syringes? special made burette?

3.how can I control the rate of adding TPP? and how many drops per min?

4.is the rate of stirring(7000 rpm) while adding the TPP ok?

any suggestion will do

thank you

sorry for the long description

In my laboratory, I have an analog centrifuge (does not show real RPM value). Its' brochure indicates the range is 300-3000 RPM. The regulator is marked from 1 to 10. Is there any way to determine the RPM in this model since it has no digital screen to show the RPM?

As it is well known fact that nano-particles can easily aggregate during nucleation/ synthesis part due to high surface energy..by reading literature, I came to know that surfactants can help to prevent this but is there any other method by which we can prevent aggregation of nano-particles without using chemical surfactants?.. Thank you in advance for your valueable time, suggestions and help. ..

What should be the optimum concentration or volume of acetic acid for chitosan nanoparticles synthesis?

Has anyone synthesised water soluble Fe3O4 magnetic nanoparticles? Or Fe3O4 particles with an aminosylane cover?

if so, which method did you use?

Another question: it is described in literature (J. Phys. Chem. B 2005, 109, 3879-3885) that Fe3O4 magnetic particles form a colloidal solution and remain dispersed in the fluid even in the presence of the external field. does this means that the particles do not react to the magnetic field?

How can i synthesize silver nanoparticle?

Why agglomeration occurs during aliginate nanoparticles synthesis.

How agglomeration can be avoided in aliginate nanoparticles synthesis

Can someone define detailed protocol with precautionary measures

Could somebody please share some references that compares these two parameters in terms of particle size and morphology. Also, could tuning the concentration of iron salts or the addition rate of the alkaline have a similar effect in changing particle size and morphology?

Thanks

Hello,

I am trying to form a pellet of PMMA particles. I have tried centrifuging for 1 hour at 26000 RPM (highest the centrifuge I have will go) but the particles do not form a pellet they just clump/form strands thoughout the liquid.

I have also tried in a 1.5mL eppendorf (narrower tube) only going to 15000RPM max speed for 1 hour but the particles form a layer at the top.

Not sure if these particles are impossible to form a pellet or if there is anything else I can do?!

I have about 20% particles to water ratio and am using a 1mL volume in a centrifuge vial that is quite high diameter (compared to eppendorf) at around 1cm diameter.

Thank you.

DEAR ALL MEMBERS, I am Ph D and have research experience in Nanotechnology specifically focusing Nanoparticles synthesis using plant source, biopolymer, and characterization for antimicrobial, antioxidants, anticancer and wound healing applications. I also studied nanoparticle DNA toxicity and Nanoparticles toxicity to various organs in Zebrafish. I Need suggesting what other areas experience in nanotechnology will help to to broaden my expertise that will helpful to build my research and post doctorate career. Thank in advance

Hello everyone,

I want to know whole chemistry behind synthesis of boron nanoparticle via chemical and biogenic methods. Focussing on why naked boron is not used as I have seen in papers, boron is complexed with some other material like Ag/Zn metal or any other polymer or salt. ALso I want to know the reaction mechanism of Boron nanoparticle synthesis via both biogenic & chemical synthesis approach.

In generall SDS is an insulator due to its long alkyl chain and hence it prevents the electron transport.

Hi, I'm trying a procedure to synthesis nano ZIF-90 in water for specific application, but there is some problem. pxrd pattern for as-synthesized MOF is not completely compatible with charactristic XRD pattern of ZIF-90, in terms of tetha. on the other side, as article indicated, i choose 1 to 40 ratio of zinc acetate to 2-imidazole carboxaldehyde to obtain particles with the scale of 100 nm, but led to really low yield, there is not another way to reach nanosize ZIF-90? I appreciate if anyone has the same experience and could help me.

mandatory work need to be carried out

I am very much confused, may be i have no knowledge regarding this issue.

We claim that in nanoparticle synthesis, the particles are pristine but when we go with the FTIR analysis of the samples, we detect the functional groups or biomolecules of the chemicals we used during the synthesis. If our samples still have the functional groups of the chemicals used during the synthesis how we still claim the purity of our nanoparticles?

I want to know the factors affecting scale up and is kinetic data a parameter in that?

If it possibility to take Metal doped nano SnO_2.  Please guide me for measurements

Hello,

I have to explain why the first UV-vis spectra's peak is near 530 nm (purple color) and when I did a repetition it showed the peak near 600 nm (violet color). I know that violet color and the peak near 600 nm shows the agglomeration of the particles, but I need a scientific explanation. Thank you very much for the help!

I'm adding some key points below: