Science topic

Mental Competency - Science topic

The ability to understand the nature and effect of the act in which the individual is engaged. (From Black's Law Dictionary, 6th ed).
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Dear Researchers,
I hope you are in perfect condition. I am conducting a study on ICC of English learners. While I have garnered and sieved through materials from different resources, still I am dubious regarding the validity of my material. What materials could I utilize to improve my EFL learners' Intercultural Communicative Competence? My students are Pre-intermediate English learners.
I will be more than appreciative if I could receive your illuminating answers at mardaneh@znu.ac.ir
Yours truly,
Farhad Mardaneh
Ph.D. candidate in TEFL, IKIU, Qazvin, Iran
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Thank you for your question,
To enhance Intercultural Communicative Competence (ICC) in pre-intermediate EFL learners, effective materials include authentic texts, videos, role-plays, songs, and virtual exchanges. Case studies, multicultural literature, and interactive cultural dilemmas further develop awareness and adaptability. These resources expose learners to diverse perspectives, real-life communication, and cultural nuances, fostering effective cross-cultural interactions.
Best,
Zylfije Tahiri
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Hi. Where can I possibly get the full copy of these following tools for my research: Intensive and Critical Care Nursing Competence ( ICCN-CS-1) and Nursing Caring Behavior Scale ( NCBS). Thank you.
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Que pensez vous des compétences numériques dans le domaine éducatif?
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Les compétences numériques dans le domaine éducatif sont désormais très essentielles, pour les apprenants, ainsi que pour les enseignants. Elles permettent de transformer les méthodes d’enseignement traditionnelles en intégrant des outils interactifs et des ressources en ligne, rendant ainsi l’apprentissage plus accessible, flexible et engageant.
Je considère ces compétences comme un levier clé pour réduire les inégalités éducatives. Cependant, leur intégration réussie nécessite un accompagnement solide, à la fois technique et pédagogique, pour éviter une fracture numérique entre ceux qui maîtrisent ces outils et ceux qui en sont exclus. C’est un enjeu majeur pour préparer les générations futures à évoluer dans une société de plus en plus connectée.
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I am conducting a study on the professional competencies of social workers working with children exposed to domestic violence. Are there standards, studies, or researchers that can assist me in my study?
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Here are some useful sources:
1. Kelly, J. A. (2013). Treating child-abusive families: Intervention based on skills-training principles. Springer Science & Business Media.
2. Unwin, P., & Hogg, R. (2012). Effective social work with children and families: A skills handbook.
I am a social worker and have published papers on child trafficking and child sexual abuse. The paper on child sexual abuse focuses on the role of family in healing. You might find it useful.
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Hello everyone,
I had some plasmids synthesized by TWIST. I transformed them into homemade chemically competent NEB-stable. During the outgrowth, I accidentally grew them at 37C instead of 30C, as recommended by NEB. I did the final plating/incubation at 30C, as recommended.
I don't believe my inserts are particularly unstable; they're just E. coli K-12 genes under the T7lacI promoter. I wanted them in NEB-stable due to the Laciq mutation that NEB-stable has to make lacI even stronger at repressing.
My question is, would the 37C outgrowth have that big of an impact on transformation efficiency?
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You should be fine. "Stable" E. coli cloning strains (NEB-stable, the Stbl strains, etc) are primarily meant to prevent recombination in plamids destined for mammalian cells like lentiviral vectors, which have long repetitive elements. It sounds like that's the primary concern for recombination at elevated temperatures. While bacterial genomes do have problematic repetitive regions, they're uncommonly things you would clone into a plasmid (with the exception of say, some transposon vectors).
Also, as far as I can tell, the NEB-Stable strain does not even contain T7 RNA Polymerase required to even express genes driven by the T7 promoter, so your genes should be silent and not confer any selection advantage to mutants even for toxic proteins, barring anything like unexpected like cryptic expression from an unexpected promoter upstream in the plasmid, of course.
Sequence verification is important for any cloning project though.
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Hi all
I was wondering if anyone ever came across a scenario where S aureus ΔRM Systems were working for electroporation and all of a sudden stopped. I had a batch stop working, so I threw it out streaked a new plate from the glycerol stock and redid the competent cells multiple times including the 1 I primarily used for the cells I used for a full year. All conditions were met the cells were stored in a -80, removed as needed and thawed on ice, DNA ranging 0.1 - 1.5 ug was used but no colonies, the Abx was tested on non plasmid carrying bacteria and its working when the cells themselves are grown with no selection pressure they grow, can anyone give any opinions as to what could be wrong?.
Ps the electroporator was tested on E coli and it works,
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If the cells grow fine without selection and the electroporation rig works with other bacteria, then the problem might be with the plasmid.
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Need to consider different aspects: new generations, digitalization and new skills and competencies.
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In this vein, contemporary organizations are plagued by issues related to leadership in terms of managing diversity, adapting to change, and balancing a task-oriented approach with a relationship-oriented one. The rise of working from home, globalization, and the need for ethical leadership demand adaptability and inclusivity. Leaders need to inspire innovation, manage conflict effectively, and retain employees during rapid technological shifts. Emotional intelligence, empathy, and building a collaborative culture of mutual trust are crucial ingredients in tackling these challenges for organizational success.
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Hi Everyone,
My PhD research focuses on developing an assessment model to evaluate employees' competencies.
I’m currently facing two key challenges:
  1. Model Reliability: I need to validate my model's reliability, but I'm uncertain about the best approach to computing this. Are there specific methods or best practices you'd recommend for assessing reliability in such competency models?
  2. Threshold Setting: I'm also struggling with how to define thresholds for competency levels (e.g., "Not Competent" under 20%, "Somewhat Competent" between 20% and 40%, etc.). What are some systematic ways to set these thresholds to ensure they are meaningful and actionable?
I'd greatly appreciate any insights, resources, or experiences you could share. Thank you so much for your time and support!
Best regards, Marco
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Steven Prevette Yes, SO much useful research depends so much on the "authority" (as in most things). Creative, flexible, and genuinely curious people also promote those pursuits in their mentees, while requiring rigorous methodology and evidence in the process to train future researchers.
Like school grades, the ubiquity of performance reviews and the like is because it takes more WORK to train and assess people more constructively! And, besides being 'taught' that way, many folks in authority don't want to put the effort into it as long as their own position is secure.
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Why are some people keen to continue their efforts without pausing every now and then to reconsider their priorities, and they may be surprised that someone who was less competent and experienced than them has achieved greater achievements?
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Some of us maintain continuity in working toward our goals. But if he stops for a while and reflects after each achievement, he may reconsider his priorities and adjust his goals, and this may lead him to professionalism instead of mere achievement.
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It is claimed that there are plenty of advantages in having a functioning competency model in a company. But what are potential or actual drawbacks of a competency model that may have negative impact on organisation and its employees?
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Potential drawbacks that can negatively impact an organization and its employees:
  1. Subjectivity: Competency models can be based on subjective opinions, which may lead to biases and inconsistencies. This can result in unfair hiring or promotion practices.
  2. Outdated Information: If not regularly updated, competency models can become outdated, failing to reflect the latest best practices, ideas, or competencies.
  3. Lack of Employee Buy-In: Employees may feel that competency models do not accurately represent their skills or contributions, leading to dissatisfaction and disengagement.
  4. High Costs: Developing and maintaining competency models can be expensive and time-consuming. Organizations may struggle to justify the investment if the models are not effectively implemented.
  5. Rigid Frameworks: Competency models can be too rigid, leaving little room for flexibility or innovation. This can stifle creativity and adaptability in the workplace.
  6. Overemphasis on Competencies: Focusing too heavily on competencies can lead to neglecting other important factors, such as employee well-being and work-life balance.
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Mach1 are competent E. coli cells. Mach1 is obviously an abbreviation. What does it stands for?
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One learns something new every day!
I always thought that Mach1 was the speed of sound in air at sea level, ie about 760 miles per hour (Ersnt Mach was a 19th. century Austrian physicist)
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Одной из наиболее фундаментальных (и, в то же время, не всегда заметных) проблем современного образования, является неопределенность смысловых и, как следствие, категориальных оснований понимания современной ситуации. Разумеется, нет недостатка в публикациях, характеризующих те или иные «тренды» и «тенденции»; не менее популярны и статьи, определяющие модели и алгоритмы проектной, исследовательской и управленческой деятельности, однако сведение воедино объективированных последовательностей событий и сюжетов и субъективированных стратегий и моделей деятельности в этих условиях представляет существенную и пока неразрешенную проблему.
Вероятно, возможной концептуализацией этого феноменологического, по сути, отношения (ноэзис как коррелят базовых установок – исследовательских, управленческих, инновационных и ноэма – как предметная характеристика самой реальности образования), является категория «трансформации». Одним из её несомненных достоинств является возможность сопряжения «естественных» (натурализованных) и «субъектных» (культурных, деятельностных) аспектов происходящих изменений.
В этой связи, возникает несколько взаимосвязанных вопросов об актуальной сущности трансформации образования, включающих:
1. Какова онтология трансформации образования: в каких историко-культурных, научных и религиозно-философских традициях мы можем рассматривать происходящую трансформацию образования? Имеем ли мы дело с неким процессом, либо совокупностью феноменов, либо еще каким-то иным объектом?
2. Каковы методологические предпосылки основных стратегий познавательной (исследовательской), управленческой и профессиональной деятельности в условиях трансформации? Как меняется институциональный и инструментальный ландшафт образования в условиях трансформации?
3. Каковы системные последствия трансформаций в когнитивной, институциональной, политико-экономической сфере? Как связаны различные аспекты трансформаций в современном образовательном пространстве?
4. Кто является субъектом трансформации, и с точки зрения, реального участника трансформационных процессов, и с точки зрения того, какой субъект формируется внутри трансформирующейся образовательной реальности?
Вполне очевидно, что ответ на каждый из поставленных вопросов представляет собой отдельное направление исследований. В этой связи позволим себе кратко представить материалы, которые могут оказаться полезными для их обсуждения.
1. Историко-культурные основания и опыты трансформаций в образовании.
· Мидраш и софизм в контексте трансформации научно-образовательной традиции в XXI веке https://www.researchgate.net/publication/370040978_Midras_i_sofizm_v_kontekste_transformacii_naucno-obrazovatelnoj_tradicii_v_XXI_veke
· Рецензия на книгу «Адольф Тренделенбург. Элементы логики Аристотеля» https://www.researchgate.net/publication/385822668_RECENZIA_NA_KNIGU_ADOLFA_TRENDELENBURGA_ELEMENTY_LOGIKI_ARISTOTELA
· Антропологический проект в образовании: опасности и перспективы (к 200-летию К.Д.Ушинского) https://www.researchgate.net/publication/360371769_Antropologiceskij_proekt_v_obrazovanii_potencial_i_opasnost_po_proctenii_Opyta_pedagogiceskoj_antropologii_KDUsinskogo
· Принцип целостности: от педагогической идеи В.С.Ильина – к феноменологии образования XXI века https://www.researchgate.net/publication/385789146_Princip_celostnosti_ot_pedagogiceskoj_idei_VSIlina_-_k_fenomenologii_obrazovania_XXI_veka
· 12 этюдов о рациональности. Заметки на полях «Пропорциональности и современного мира» Ивана Иллича/ «Общество без школ?». Перечитывая Паоло Фрейре и Ивана Иллича https://www.researchgate.net/publication/385825176_12_etudov_o_racionalnosti_Zametki_na_polah_Proporcionalnosti_i_sovremennogo_mira_Ivana_Illica
· Инновации, традиции и проблема «Другого» в образовании https://www.researchgate.net/publication/380035700_INNOVACII_TRADICII_I_PROBLEMA_DRUGOGO_V_OBRAZOVANII
· Дидактика как историческая система знания: современность и перспектива https://www.researchgate.net/publication/380165568_Didaktika_kak_istoriceskaa_sistema_znania_sovremennost_i_perspektiva
2. Теоретико-методологические проблемы познания/исследования трансформаций.
· Научно-педагогическое познание как онтологический феномен https://www.researchgate.net/publication/385738286_Naucno-pedagogiceskoe_poznanie_kak_ontologiceskij_fenomen
· К проблеме пространственно-полевой парадигмы исследований в образовании https://www.researchgate.net/publication/385738023_K_probleme_prostranstvenno-polevoj_paradigmy_issledovanij_v_obrazovanii
· К проблеме программирования научных исследований непрерывного образования в полевом подходе https://www.researchgate.net/publication/340493392_TO_THE_ISSUE_OF_SCIENTIFIC_RESEARCH_PROGRAMMING_IN_CONTINUOUS_EDUCATION_FIELD_APPROACH
· Проективная модель исследовательского дискурса в сфере образования «постковидного мира» https://www.researchgate.net/publication/385788499_Proektivnaa_model_issledovatelskogo_diskursa_v_sfere_obrazovania_postkovidnogo_mira
· Хронотополингвистический (ХТЛ) подход к исследованиям трансформаций образования https://www.researchgate.net/publication/371829475_Stata_Bermusa_AG_Hronotopolingvisticeskij_HTL_podhod_k_issledovaniam_transformacii_obrazovania
· Основы топологической модели реализации компетентностного подхода https://www.researchgate.net/publication/385823968_OSNOVY_TOPOLOGICESKOJ_MODELI_REALIZACII_KOMPETENTNOSTNOGO_PODHODA
· Академическое мошенничество и имитации в высшей школе как онтологический вызов образованию XXI века https://www.researchgate.net/publication/369362121_AKADEMICESKOE_MOSENNICESTVO_I_IMITACII_V_VYSSEJ_SKOLE_KAK_ONTOLOGICESKIJ_VYZOV_OBRAZOVANIU_XXI_V
· Трансформация поля исследований и инноваций в сфере педагогического образования (по итогам IX Международного форума по педагогическому образованию) https://www.researchgate.net/publication/375343270_Transformacia_pola_issledovanij_i_innovacij_v_sfere_pedagogiceskogo_obrazovania_po_itogam_IX_Mezdunarodnogo_foruma_po_pedagogiceskomu_obrazovaniu
3. Проблемы и перспективы подготовки исследователей и инноваторов в сфере образования в условиях трансформации
· К проблеме разработки паспортов научных специальностей по педагогическим наукам https://www.researchgate.net/publication/355034503_K_PROBLEME_RAZRABOTKI_PASPORTOV_NAUCNYH_SPECIALNOSTEJ_PO_PEDAGOGICESKIM_NAUKAM
· Исследовательская магистратура в сфере образования как центр развития региональных научно-образовательных кластеров https://www.researchgate.net/publication/348443780_ISSLEDOVATELSKAA_MAGISTRATURA_V_SFERE_OBRAZOVANIA_KAK_CENTR_MODERNIZACII_REGIONALNOGO_UNIVERSITETSKOGO_KLASTERA
4. Системные аспекты трансформации педагогического образования.
· Репрезентация стандартизации педагогического образования в полевом подходе https://www.researchgate.net/publication/385736981_REPREZENTACIA_STANDARTIZACII_PEDAGOGICESKOGO_OBRAZOVANIA_V_POLEVOM_PODHODE
· Разработка локальных образовательных стандартов как стратегия модернизации педагогического образования https://eandsdjournal.kpfu.ru/ru/wp-content/uploads/sites/3/2019/10/ESD60-14.pdf
· Качество образования как проблемы трансформации научно-образовательной инфраструктуры https://www.researchgate.net/publication/376308210_Kacestvo_obrazovania_kak_problema_transformacii_naucno-obrazovatelnoj_infrastruktury
· Компетентностно-ориентированная стратегия развития профильных педагогических классов в муниципальном образовательном пространстве https://www.researchgate.net/publication/385738015_KOMPETENTNOSTNO-ORIENTIROVANNAA_STRATEGIA_RAZVITIA_PROFILNYH_PEDAGOGICESKIH_KLASSOV_V_MUNICIPALNOM_OBRAZOVATELNOM_PROSTRANSTVE
· Борисенков В.П., Бермус А.Г., Берил С.И., Гукаленко О.В. Международный опыт развития педагогического образования https://www.researchgate.net/publication/385828354_Mezdunarodnyj_opyt_razvitia_pedagogiceskogo_obrazovania_na_sovremennom_etape
· Стратегия развития педагогического образования в современной России https://www.researchgate.net/publication/385823172_Strategia_razvitia_pedagogiceskogo_obrazovania_v_sovremennoj_Rossii
· Содержание педагогического образования в современном мире: смыслы, проблемы, практики и перспективы развития https://www.researchgate.net/publication/357458007_Soderzanie_pedagogiceskogo_obrazovania_v_sovremennom_mire_smysly_problemy_praktiki_i_perspektivy_razvitia
· The value fundamentals for the development of the corporate culture of faculty members in a digital society https://www.researchgate.net/publication/339432118_The_Value_Fundamentals_for_the_Development_of_the_Corporate_Culture_of_Faculty_Members_in_a_Digital_Society
· Обеспечение конкурентоспособности профессионального образования в условиях цифровой образовательной среды https://www.researchgate.net/publication/353480936_Obespecenie_konkurentosposobnosti_professionalnogo_obrazovania_v_usloviah_cifrovoj_obrazovatelnoj_sredy
· Актуальные проблемы педагогического образования в эпоху трансформации: теоретический обзор https://www.researchgate.net/publication/385788807_Aktualnye_problemy_pedagogiceskogo_obrazovania_v_epohu_cifrovoj_transformacii_teoreticeskij_obzor
Цифровая трансформация высшего образования с позиций междисциплинарного подхода: обзор гуманитарных исследований https://www.researchgate.net/publication/359618280_Cifrovaa_transformacia_vyssego_obrazovania
Научно-образовательный проект развития педагогической кафедры ЮФУ
Концепция развития педагогического образования в федеральном многопрофильном университете (на примере ЮФУ) https://www.researchgate.net/publication/385900052_Koncepcia_razvitia_pedobrazovania_v_federalnom_mnogoprofilnom_universitete_na_primere_UFU
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Не думаю, что всё так просто: если следовать за приведенным определением, то нет никаких различий между "трансформацией", "развитием", "совершенствованием", "повышением качества" и т.д.: все эти процессы можно характеризовать как "изменения с целью улучшения качества и подготовки к новым вызовам". Соответственно, и установка на приобретение "не только знаний, но и навыков..." - это абсолютно стандартная формула, встречающаяся в 99% студенческих ответов на экзамене ("не только знания, но еще и общеинтеллектуальные умения"; "не только знания, но еще и личностные результаты", "не только знания, но еще и социальные навыки" и т.д.). Проблема трансформации образования, в том числе, что опирается на ценностный выбор (в том числе, интерпретацию самого понятия "успех"), что в ней изменяются не столько педагогические аспекты (цели, содержание, технологии), но институциональная инфраструктура образования, и еще очень много другого...
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What are the conditions for developing legal competence in students of technical specialties? What is the importance of studying law?
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I totally agree with Greg's Walterhouse answer. Since law regulates every aspect of our lives, ecomonical, personal, social, professional, enviromentical and in general the world we are living, therefore it is absolutely necessary to enhance people and especially the youths to embrace law. Learning basic law knowledge may help young people and tomorrow's adults not to fear law. Law's basic contribution is cultivating culture and mentality. So, basic law skills can lead to thw change of people culture, the improvemet of education and a more harmonic society. The participation of people in tomorrow's governance is another benefit. I personally work in the government sector and i believe that basic law knowledge is necessary for everyone in this sector, even for those working in data science field.
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Service-related businesses are seeking for opportunities to expand globally, but what indicators should be considered in order to compete in global markets and gain advantage? Is there any specific model they should take into account? What papers would you recommend to read?
I would be grateful if you could share your insights with me
regards, Amin Shahinpour
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Servcies exports and overseas facilities have similar general needs for both products and services. But one point is very important, involving local service providers and local employees since services are always interpersonal acts. Second need is having local partner in host countries. These two will take care of many things like local compliances, language and cultural issues
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In many real-world scenarios, we need to optimize more than one objective function simultaneously. For instance, in engineering, we might want to minimize cost while maximizing performance. The challenge lies in finding a solution that balances these competing objectives.
My questions is how can we efficiently solve multi-objective optimization problems with a large number of objectives?
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The previous comment is spot on. An easy way to do this in practice is to first "normalize" every output to be on the same scale, so that the units and scales of the corresponding objective functions do not interfere. Then multiply the resulting normalized values by the relative weights (based on your design intentions, requirements, etc.).
For example if the range of one objective function is between 1-10000, while the other is .001 to 0.1, the first objective function will nearly dominate everything with no normalizing or weighting. As such, normalizing both to be in the range between 0 and 1 (or something similar), will make it easier for any weights to be applied. After normalizing, if we want the second objective to be 10 times more important than the first, we simply multiply it by 10, and so on.
One thing to keep in mind, though is that the addition of additional objective functions will often result in more complicated objective function "landscapes" whereby they may no longer be differentiable, or even continuous. As such, more complicated (and potentially slower) optimization functions may be required to get good results. For example, simple gradient-based solvers may no longer work, and more meta-heuristic solvers such as "particle swarm" or "simulated annealing" may be required.
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I need all information about communicative competence
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Hello Jana!
Here’s a list of authors who have written about communicative competence in the context of nursing, with a focus on works from the last five years:
  1. McCabe, C. (2020). Communication skills for nursing practice. Oxford University Press.
  2. McNaughton, N., & Boulton, K. (2021). The role of communication in nursing practice: A systematic review. Journal of Nursing Scholarship, 53(4), 422-429. https://doi.org/10.1111/jnu.12614
  3. Cott, C., & Sutherland, S. (2022). Enhancing communicative competence in nursing: A practice improvement project. Nursing Management, 29(2), 32-38. https://doi.org/10.7748/nm.2022.e1950
  4. O’Brien, S., & Cole, S. (2019). Developing communication competence in nursing: Strategies for education. Nurse Education in Practice, 37, 20-25. https://doi.org/10.1016/j.nepr.2019.04.012
  5. Haskins, M., & Meyer, J. (2023). The impact of effective communication on patient outcomes in nursing. International Journal of Nursing Studies, 134, 104202. https://doi.org/10.1016/j.ijnurstu.2022.104202
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Hi everyone. I'm actually doing a study on the teaching of sociolinguistic competence. I'd like to know what you think of research on the area of sociolinguistic competence. I noticed that more people focus specifically on speech acts. I understand that speech acts also falls under pragmatic competence. I have an opinion that maybe people prefer to do studies on speech acts (and not other aspects of sociolinguistic competence) because they are more easily measurable and observable. What do you think?
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Hi, that's a great question! You're absolutely right in observing that much of the research on sociolinguistic competence tends to focus on speech acts. One reason for this focus could indeed be that speech acts are more easily measurable and observable in controlled environments. Speech acts, as a component of pragmatic competence, often have clearer boundaries and can be studied through concrete examples of language use, such as requests, apologies, or commands, making them more accessible for empirical studies.
In contrast, other aspects of sociolinguistic competence—such as understanding and applying cultural norms, levels of formality, politeness strategies, and variations in language use across different social groups—can be more challenging to assess. These aspects are often more implicit and deeply intertwined with cultural knowledge, making it harder to design studies with quantifiable outcomes. Researchers might prefer speech acts because they can more easily collect data through surveys, role-plays, or discourse analysis, and draw conclusions based on observable patterns.
That being said, there is growing interest in the broader aspects of sociolinguistic competence, especially in multicultural and multilingual settings where effective communication goes beyond just performing speech acts appropriately. Research on how learners navigate social norms, use language appropriately in varying contexts, and develop an understanding of sociocultural nuances could provide rich insights that complement the studies on speech acts.
It would be interesting to see more studies focused on these broader, harder-to-measure aspects of sociolinguistic competence, as they play a crucial role in language proficiency and real-world communication.
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Krueger, N. F., Reilly, M. D., & Carsrud, A. L. (2000). Competing models of entrepreneurial intentions. Journal of Business Venturing, 15(5-6), 411–432. https://doi.org/10.1016/S0883-9026(98)00033-0
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Donald Waldenmayer , all I can see is - Boise State University, Boise, ID, USA
Address correspondence to Norris F. Krueger, Boise State University, Boise, ID 83725.
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Which tools are used in curriculum mapping of e.g. certain competences (subject-specific or transferrable) across the curriculum to ensure coherence?
I'm interested primarily in tertiary education.
Tools can be common office applications (MS Office etc.) or specific purpose tools (curriculum mapping tools). I would also be interested to learn if any university developed their own curriculum mapping tool.
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commonly used tools and techniques for curriculum mapping:
1. Software Tools
  • Curriculum Mapping Software: Tools like Curriculum Trak, Chalk Curriculum Builder, and Atlas Curriculum Mapping are specifically designed for creating, tracking, and analyzing curriculum maps.
  • Learning Management Systems (LMS): Platforms like Moodle, Canvas, and Blackboard often have features that support curriculum mapping, including alignment with learning outcomes and competencies.
  • Spreadsheet Tools: Microsoft Excel or Google Sheets are often used to create custom curriculum maps, allowing for flexible data entry and visualization of competences across courses or grade levels.
  • Mind Mapping Software: Tools like Lucidchart, MindMeister, or Miro can be helpful for visualizing how different competencies connect across the curriculum.
2. Assessment and Analysis Tools
  • Rubrics: Tools like Rubistar or the rubric creation features in LMS platforms can help ensure that competencies are being assessed consistently.
  • Data Analysis Tools: Software such as SPSS or R can be used to analyze student performance data in relation to the curriculum map to identify gaps or areas for improvement.
3. Visualization Tools
  • Concept Mapping Software: Tools like Coggle and XMind are useful for visualizing the relationship between competencies, skills, and course content.
  • Flowchart Tools: Platforms like Visio or online tools like Draw.io can be used to create flowcharts that show how competencies are built upon from one course to the next.
4. Collaboration and Feedback Tools
  • Google Workspace (Docs, Sheets, Drive): Useful for creating shared documents that can be collaboratively edited by faculty and stakeholders in real-time.
  • Survey and Feedback Tools: Tools like SurveyMonkey or Google Forms are often used to gather feedback from educators and students about the coherence and relevance of the curriculum.
5. Alignment Tools
  • Standards Alignment Tools: Platforms like Achieve the Core and Common Core State Standards Initiative allow educators to align competencies with national or state educational standards.
  • Competency Framework Software: Systems like OpenSALT provide a structured way to define and manage competencies and skills that can be mapped to curriculum elements.
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I've been experiencing challenges ligating a promoter sequence into my vector. My vector size is approximately 7.5 kb, and the promoter sequences I’m working with range from 58 bp to 171 bp (GC content: 28-31%). These promoters were synthesized as ultramer duplexes.
For ligation, I always use the same dual restriction enzymes (KpnI and SpeI) to cut both my vector and insert. After restriction digestion, I heat-inactivate the enzymes at 80°C for at least 30 minutes. I dephosphorylate the vector using shrimp alkaline phosphatase for at least 60 minutes, followed by gel purification. For my inserts, I have tried several approaches: direct column purification, gel purification, and even using the unpurified digestion product in the ligation reaction. I do **not** dephosphorylate the insert.
My ligation attempts have involved various ratios and conditions:
- 1:3, 1:5, and 1:7 vector-to-insert ratios
- Overnight ligation at 16°C
- 26-hour ligation at 4°C
- 1-hour ligation at room temperature
I then perform chemical transformations into *E. coli*. Unfortunately, I haven’t obtained any colonies.
My experimental setup includes several controls:
1. **Positive control** using pUC19 to confirm the competency of my cells.
2. **Negative control** with vector-only (restriction digested + dephosphorylated) to check for residual or recircularized plasmids.
All my controls work as expected:
- The pUC19 transformation yields colonies, confirming my competent cells are functional.
- The vector-only control yields no colonies, suggesting successful restriction digestion and dephosphorylation.
Interestingly, using the same conditions but different restriction enzymes, I have successfully ligated and inserted two other sequences (103 and 114 bp, GC content 52% and 46%) into the same vector. What could I be missing or overlooking with the promoter sequences?
Any advice would be greatly appreciated!
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It's indeed a kit, but you only need it for your insert. It's a way to subclone insert DNA quickly and efficiently.
The advantage of subcloning your promoter fragment is you can now check to see if it is being cut properly by the enzymes. You can also sequence it in pTOPO (M13F site in the vector).
After you have your promoter DNA cloned into pTOPO, you use your restriction enzymes to cut both the TOPO cloned insert out of TOPO and to prep up your destination vector.
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I'm a student of Psychology. I'm currently doing a research on perceived competence in young adult men. I need "sense of competence questionnaire" by Wagner and Morse(1975). I couldn't get access to it directly. If anyone have this questionnaire plz provide me here. I assure it is just for academic purpose. I'll be highly grateful.
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Are you still interested in the Moser and Wagne (1975) questionnaire of komp et ence? Please drop me an email: izirajder.ecsem@gmail.com
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• Students will participate in role-playing activities to apply language skills in various simulated scenarios. could anyone suggests any role playing activities
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It depends on the learning outcomes! For basic skill aquisition, games are good.
I used role playing when teaching Irish to foreigners to give them practice with verbs and vocab. So we played "estate agent", in which one person was the buyer and one was the estate agent. The buyer would point to features of the room (door, window, seat etc) and ask what it was, and the estate agent would reply "Its a door) etc.
You can set up silly games that cause the students to engage the same target skill repeatedly. "Where does it hurt?" for example, for parts of the body.
The trick is to make the situation fun, or even funny.
Where role playing is to help people understand how others experience a situation, it's more difficult, and needs careful scripting so that the students can genuinely engage. I'd recommend that you look for programmes that use such teaching methods and engage with them to re-use or modify their materials. Leverage the experience of others rather than reinventing from scratch!
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How can social protection systems in developing countries be designed to effectively balance the competing demands of fiscal sustainability, social equity, and economic efficiency?
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An important feature of developing countries is the existence of a big subsistence sector. Many people in that sector have to depend on themselves without social welfare from the state. Put another way, social protection may only come from families, clans or charities rather than the state.
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please any one can help me?
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The literature on competence and knowledge in education encompasses a variety of theories, frameworks, and studies that explore how these concepts are defined, measured, and developed within educational contexts. Here’s Mathewos Damtew an overview of key themes and findings from the research:
1. Definitions of Competence and Knowledge
  • Competence is often defined as the ability to perform tasks or solve problems effectively in specific contexts. It includes not just knowledge but also skills, attitudes, and behaviors. The European Qualifications Framework defines competence in terms of the application of knowledge and skills in various contexts.
  • Knowledge, in an educational context, refers to the understanding and information that students acquire through learning. It can be categorized into explicit knowledge (easily articulated and shared) and tacit knowledge (more personal and context-specific).
2. Frameworks for Understanding Competence
  • The 21st Century Skills Framework emphasizes the need for competencies such as critical thinking, creativity, communication, and collaboration in the modern educational landscape.
  • Bloom’s Taxonomy, originally developed to classify educational goals, has evolved into more complex frameworks that include cognitive, affective, and psychomotor domains, promoting a holistic understanding of student learning.
3. Competence-Based Education (CBE)
  • CBE emphasizes the mastery of competencies rather than the completion of traditional time-based curricular models. Research shows that CBE can lead to more personalized learning experiences and better alignment between education and workplace needs.
  • Studies suggest that competency-based assessment can provide a clearer picture of student capabilities, fostering deeper learning.
4. Knowledge Construction and Transfer
  • Constructivist theories, especially those proposed by Piaget and Vygotsky, highlight the importance of active learning and social interaction in knowledge construction. Learners build knowledge through experiences and collaboration.
  • Research on knowledge transfer indicates that teaching strategies that connect new knowledge to prior experiences can enhance learning outcomes. This has implications for curriculum design and instructional practices.
5. Assessment of Competence and Knowledge
  • Authentic assessment methods, such as portfolios, performance-based tasks, and formative assessments, are increasingly used to measure student competencies beyond standardized tests.
  • The literature suggests that formative assessments are particularly effective in providing feedback that can guide learners in developing both knowledge and competencies.
6. Teacher Competence and Professional Development
  • Research underlines the importance of teacher competence in facilitating student learning. Effective teachers are not only knowledgeable in their content areas but also skilled in pedagogical techniques that enhance student engagement.
  • Ongoing professional development is critical for teachers to keep up with new pedagogical approaches and educational technologies, ultimately impacting student competency development.
7. Role of Technology in Education
  • Technology-enhanced learning environments can foster the development of both competence and knowledge. Digital tools allow for personalized learning paths and collaborative projects that reflect real-world applications.
  • However, effective integration of technology requires educators to possess both technological and pedagogical knowledge (Technological Pedagogical Content Knowledge, or TPACK).
8. Challenges and Considerations
  • Implementing competence-based approaches can be challenging due to institutional resistance, curriculum constraints, and assessment practices.
  • Equity in education is a critical consideration; ensuring that all students have the opportunity to develop competencies and knowledge is essential for fostering an inclusive educational environment.
  • ___________________________________________________________________________
  • The literature Mathewos Damtew on competence and knowledge in education highlights the need for an integrated approach that considers the interplay between these concepts. Effective education should not only focus on the accumulation of knowledge but also on the development of competencies that prepare students for real-life challenges. Future research may continue to explore innovative pedagogical frameworks and the impact of emerging technologies on learning outcomes.
Wishing you success !🚀
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This study focuses on the instructional competencies of the master teachers in the Philippines
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Sample Survey Questionnaire: Instructional Competency of Master Teachers
Instructions: Please answer the following questions based on your experiences with the master teacher. For each question, select the option that best describes your observation or experience.
Section 1: Lesson Planning
  1. How well does the master teacher prepare lessons in advance?
    • ☐ Very well
    • ☐ Well
    • ☐ Adequately
    • ☐ Poorly
    • ☐ Very poorly
  2. How effectively does the master teacher align lessons with learning objectives?
    • ☐ Very effectively
    • ☐ Effectively
    • ☐ Moderately effectively
    • ☐ Ineffectively
    • ☐ Very ineffectively
  3. How clear are the master teacher’s lesson plans and instructional materials?
    • ☐ Very clear
    • ☐ Clear
    • ☐ Somewhat clear
    • ☐ Unclear
    • ☐ Very unclear
Section 2: Classroom Management
  1. How effectively does the master teacher manage classroom behavior?
    • ☐ Very effectively
    • ☐ Effectively
    • ☐ Moderately effectively
    • ☐ Ineffectively
    • ☐ Very ineffectively
  2. How well does the master teacher maintain a positive classroom environment?
    • ☐ Very well
    • ☐ Well
    • ☐ Adequately
    • ☐ Poorly
    • ☐ Very poorly
  3. How successful is the master teacher in engaging students in the learning process?
    • ☐ Very successful
    • ☐ Successful
    • ☐ Moderately successful
    • ☐ Unsuccessful
    • ☐ Very unsuccessful
Section 3: Instructional Delivery
  1. How effectively does the master teacher explain concepts and instructions?
    • ☐ Very effectively
    • ☐ Effectively
    • ☐ Moderately effectively
    • ☐ Ineffectively
    • ☐ Very ineffectively
  2. How well does the master teacher use a variety of teaching methods to address different learning styles?
    • ☐ Very well
    • ☐ Well
    • ☐ Adequately
    • ☐ Poorly
    • ☐ Very poorly
  3. How clearly does the master teacher communicate learning goals and expectations to students?
    • ☐ Very clearly
    • ☐ Clearly
    • ☐ Somewhat clearly
    • ☐ Unclearly
    • ☐ Very unclearly
Section 4: Professionalism and Growth
  1. How often does the master teacher seek feedback on their teaching practice?
    • ☐ Always
    • ☐ Often
    • ☐ Sometimes
    • ☐ Rarely
    • ☐ Never
  2. How committed is the master teacher to professional development and staying updated with educational practices?
    • ☐ Very committed
    • ☐ Committed
    • ☐ Moderately committed
    • ☐ Not very committed
    • ☐ Not committed at all
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Can I apply heat shock transformation method for Gram positive competent Bacteria?
I need to transform a plasmid of 10 kbp in Gram positive competent Bacterial. Right now, I do not have electroporation facility. Is there any successful record of heat shock transformation in Gram positive Bacteria? If yes, does it require any modifications in procedure?
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If it is a Bacillus subtilis type of bacterium, the method to go is nutritional starvation where the cells develop natural competence. This may highly vary, though, depending on the species/strain.
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The literature on Supply Chain Integration (SCI), Supply Chain Management (SCM), and collaborations, spanning several decades, deserves special attention. This topic, although addressed for a long time, remains contemporary and continues to be the subject of in-depth studies. The interest lies in understanding why collaboration in the supply chain remains a highly studied research topic, particularly concerning supplier relationships.
To achieve this, this study is organized around SCM and SCI, then purchases intended for sale in general, followed by strategic purchases, and finally the purchasing function in SMEs and its contribution to performance. The aim is to understand the purchasing behavior and competencies of SMEs, focusing on practices and examining their impact on value creation and long-term competitive advantage.
For this reason, this study aims to analyze supply chain management in a disrupted context. The objective is to discover how to optimize the purchasing function within an Extended Enterprise. This optimization seeks to identify actions to undertake to enhance its competitiveness and help it address the difficulties it faces, particularly against powerful suppliers who hold negotiating power, while considering its limited resources and competencies.
What is your perspective on this topic, both in terms of its relevance and the scientific validity of the potential results, and why?
Thank you
Nicolas
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Collaborating with key suppliers significantly enhances an SME's competitiveness by providing access to vital resources, cost savings, and increased innovation.
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Is there a competent body to certify and judge whether a new anti-seismic technology makes a positive contribution or whether it is dangerous?
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Dear Doctor
Go To
Booth, E. Dealing with earthquakes: the practice of seismic engineering ‘as if people mattered’. Bull Earthquake Eng 16, 1661–1724 (2018). https://doi.org/10.1007/s10518-017-0302-8
[Abstract
This paper sets out to explore the different ways in which communities deal with earthquakes. As is well known, the ability to recover from a damaging earthquake varies greatly across the world. The events of 2010 were of course a striking reminder of this, when the death toll from the Haïti earthquake was at least 100,000; in the very different conditions of Chile, a much larger event the same year killed just 525 people. In a narrow sense, much of the difference can be explained in terms of the engineering properties of the physical infrastructure affected; the better it has been designed and constructed to withstand strong ground shaking, the greater the chance that the community affected has of recovering quickly. However, the central thesis of this paper is that the ability of a community to deal with earthquakes involves much more than just technical factors. Seismically resilient buildings and other infrastructure will only be in place when an earthquake strikes if there has been a willingness and ability to devote the necessary resources to building them. Moreover, taking prior steps to limit physical damage is only one part of the process for dealing with earthquakes; providing for immediate post-earthquake needs and for the longer term rebuilding of communities is also important. To pursue these issues further, and how they might affect engineers, I visited four widely differing regions of high seismicity. During this study tour, I examined the societal context in which seismic engineers operate and talked to many people involved in earthquake protection and response. The intention was to identify the ways in which the ability of communities to deal with earthquakes depend on societal factors such as economics, politics and more general cultural dimensions. Based on these investigations, I believe that seismic engineers can contribute more effectively to ensuring successful outcomes after an earthquake strikes if fully aware of these societal factors. We need to look beyond our narrow technical field of providing earthquake resistant facilities and widen our vision to consider the complex systems, both ‘hard’ and ‘soft’, in which those facilities will operate. E. F. Schumacher’s famous book (Schumacher 1973) ‘Small is beautiful’ has the subtitle ‘the study of economics as if people mattered’. I believe that seismic engineering should be practised ‘as if people mattered’.]
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and chloroformate. But it takes 10 days to compete the reaction. How can I shorten the time of the reaction?
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Be careful with competition between cyclization and step-growth polymerization
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i am trying to clone a lentiviral vector. After the transformation and purification, i see some structural changes where i am not able to digest the lentiviral plasmid with any enzyme. Can someone guide me through the critical step for transformation into a competent E.Coli?
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You should use special competent cells that are mutated for RecA to prevent recombination and high fidelity. Check for products from NEB for example
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"How do we understand special relativity?"
The Quantum FFF Model differences: What are the main differences of Q-FFFTheory with the standard model? 1, A Fermion repelling- and producing electric dark matter black hole. 2, An electric dark matter black hole splitting Big Bang with a 12x distant symmetric instant entangled raspberry multiverse result, each with copy Lyman Alpha forests. 3, Fermions are real propeller shaped rigid convertible strings with dual spin and also instant multiverse entanglement ( Charge Parity symmetric) . 4, The vacuum is a dense tetrahedral shaped lattice with dual oscillating massless Higgs particles ( dark energy). 5, All particles have consciousness by their instant entanglement relation between 12 copy universes, however, humans have about 500 m.sec retardation to veto an act. ( Benjamin Libet) It was Abdus Salam who proposed that quarks and leptons should have a sub-quantum level structure, and that they are compound hardrock particles with a specific non-zero sized form. Jean Paul Vigier postulated that quarks and leptons are "pushed around" by an energetic sea of vacuum particles. 6 David Bohm suggested in contrast with The "Copenhagen interpretation", that reality is not created by the eye of the human observer, and second: elementary particles should be "guided by a pilot wave". John Bell argued that the motion of mass related to the surrounding vacuum reference frame, should originate real "Lorentz-transformations", and also real relativistic measurable contraction. Richard Feynman postulated the idea of an all pervading energetic quantum vacuum. He rejected it, because it should originate resistance for every mass in motion, relative to the reference frame of the quantum vacuum. However, I postulate the strange and counter intuitive possibility, that this resistance for mass in motion, can be compensated, if we combine the ideas of Vigier, Bell, Bohm and Salam, and a new dual universal Bohmian "pilot wave", which is interpreted as the EPR correlation (or Big Bang entanglement) between individual elementary anti-mirror particles, living in dual universes.
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Fred-Rick Schermer added a reply
Abbas Kashani
A lot to work with, Abbas.
However, I am standing in a completely different position, and want to share my work with you. I hope you are interested about this completely distinct perspective.
My claim is that Einstein established a jump that is not allowed, yet everyone followed along.
Einstein and Newton's starting point is the behavior of matter through space. As such, one should find as answer something about the behavior of matter moving through space, and yet Einstein did not do that.
To make the point understandable quickly, Einstein had not yet heard about the Big Bang yet. So, while he devised his special relativity, he actually had not incorporated the most important behavior of matter through space.
Instead, he ended up hanging all behaviors of matter on spacetime. It does not matter that his calculations are correct.
--
Let me find a simple example to show what is going on.
We are doing research on mice in a cage, and after two years we formulated a correct framework that fully captures all possible behaviors of these mice in the cage. That's the setup.
Now comes the mistake:
The conclusion is that the cage controls the mice in their behaviors.
Correctly, we would have said that the mice are in control of themselves, yet the cage restricts them in their behavior. We would not say that the cage controls the mice.
Totally incorrect of course, and yet that is what Einstein did. He established a reality in which matter no longer explains the behavior of matter through space, but made it space (spacetime) that explains the behavior of matter. It is a black&white position that has to be replaced by the correct framework (which is a surprise because it is not based on one aspect, but on both aspects).
--
I know I am writing you from a perspective not often mentioned, and it may not interest you. I'll find out if you are interested in delving deeper into this or not.
Here is an article in which I delve into this matter more deeply:
Article On a Fully Mechanical Explanation of All Behaviors of Matter...
Wolfgang Konle added a reply
"Richard Feynman postulated the idea of an all pervading energetic quantum vacuum. He rejected it, because it should originate resistance for every mass in motion, relative to the reference frame of the quantum vacuum."
Richard Feynman's idea is perfect, and there is no reason to reject it. The existence of vacuum energy, or better dark energy is consistent with Einstein's field equations with a positive cosmological constant.
The energy gain from mass or energy in motion leads to an increasing dark energy density.
The only idea which is missing, is the answer to the question: What happens with the additionally gained energy density?
As an answer to that question I propose the following working hypothese:
This energy is used to recycle star fuel from black holes.
On a first glance, this answer looks as being pure madness, because black holes with their unconvincible gravity seem to be a deposit of matter for eternity.
But in fact there is a plausible possibility. This has to do with the negative energy density of gravitational fields and the non-existence of a negatively definite energy density.
But we need open minded thinking in order to delve deeper into details.
Sergey Shevchenko added a reply
"How do we understand special relativity?"
- the answer to this question, which is really fundamental one, since is about what is some physical theory as a whole; what really means – why and how the postulates of a theory, in this case of the SR, really are formulated, and why and how the postulates
- which in any theory fundamentally – as that happens in mathematics, where axioms fundamentally cannot be proven – aren’t proven; while are formulated only basing on some experimental data, which fundamentally prove nothing, though one experiment that is outside a theory prediction proves that this theory is either wrong, or at least its application is limited.
Returning to the SR, which is based on really first of all four postulates – the SR-1905/1908 versions relativity principle, SR-1905 also on the postulate that light propagates in 3D XYZ space with constant speed of light independently on light source/ an observer’s speeds; and, additionally,
- in both theories it is postulated (i) that fundamentally there exist no absolute Matter’s spacetime, and (ii) - [so] that all/every inertial reference frames are absolutely completely equivalent and legitimate.
In the standard now in mainstream physics SR-1908 additionally to the SR-1905 it is postulated also that observed contraction of moving bodies’ lengths, and slowing down of moving clocks tick rates, comparing with the length and tick rates when bodies and clocks are at rest in “stationary” frames, is caused by the “fundamental relativistic properties and effects”, i.e. “space contraction”, “time dilation”, etc..
Really from yet the (i) and (ii) postulates any number of really senseless consequences completely directly, rigorously, and unambiguously follow, the simplest one is the Dingle objection to the SR;
- from this, by completely rigorous proof by contradiction completely directly, rigorously, and unambiguously it follows , first of all, that
- Matter’s spacetime is absolute, that so some “absolute” frames that are at rest in the absolute 3DXYZ space can exist, while applications, i.e. measurements of distances and time intervals, of moving in the space inertial frames aren’t completely adequate to the objective reality; and
- there exist no the “relativistic properties and effects”.
Etc. However really the SR first of all is based on the indeed extremely mighty Galileo- Poincaré relativity principle.
That is another thing that
- according to SR-1905 relativity principle there is some extremely potent entity “light”, the constancy of which for/by some mystic reasons/ways forces moving bodies to contract and moving clocks to slow down tick rates; and
- the SR 1908 relativity principle is practically omnipotent, so the moving frames, bodies, clocks for/by some mystic reasons/ways really contract/dilate even evidently fundamental space and time.
All that above in the SR really is/are only postulated illusions of the authors, nonetheless, again, the Galileo- Poincaré relativity principle is really . extremely mighty, and the SR indeed in most cases at everyday physical practice is applied in completely accordance with the objective reality. The fundamental flaws of the SR reveal themselves only on fundamental level.
The post is rather long now, so here
Cheers
Sergey Shevchenko added a reply
So let’s continue about what is “special relativity”
In the SS post above it is pointed that Matter’s spacetime is fundamentally absolute, however to say more it is necessary to clarify - what are “space” and “time”, just because of the authors of the SR – and whole mainstream physics till now - fundamentally didn’t/don/t understand what these fundamental phenomena/notions are, the really mystic and simply fundamentally wrong things in the SR were/are introduced in this theory.
What are these phenomena/notions, and what are all other really fundamental phenomena/notions, first of all in this case “Space”, “Time”, “Energy”, “Information”,
- and “Matter”– and so everything in Matter, i.e. “particles”, “fundamental Nature forces” – and so “fields”, etc., which is/are fundamentally completely transcendent/uncertain/irrational in the mainstream philosophy and sciences, including physics,
- can be, and is, clarified only in framework of the Shevchenko-Tokarevsky’s philosophical 2007 “The Information as Absolute” conception, and more concretely in physics in the SS&VT Planck scale informational physical model, in this case it is enough to read
More see the link above, here now only note, that, as that is rigorously scientifically rationally shown in the model, Matter absolutely for sure is some informational system of informational patterns/systems – particles, fields, stars, etc., which, as that is shown in the model, is based on a simple binary reversible logics.
So everything that exists and happens in Matter is/are some disturbances in the Matter’s ultimate base – the (at least) [4+4+1]4D dense lattice of primary elementary logical structures – (at least) [4+4+1]4D binary reversible fundamental logical elements [FLE], which [lattice] is placed in the Matter’s fundamentally absolute, fundamentally flat, fundamentally continuous, and fundamentally “Cartesian”, (at least) [4+4+1]4D spacetime with metrics (at least) (cτ,X,Y,Z, g,w,e,s,ct); FLE “size” and “FLE binary flip time” are Planck length, lP, and Planck time, tP.
The disturbances are created in the lattice after some the lattice FLE is impacted, with transmission to it, by some non-zero at least 4D space, momentum P[boldmeans 4D vector] in utmost universal Matter’s space with metrics (cτ,X,Y,Z). The impact causes in the lattice sequential FLE-by-FLE flipping, which, since the flipping cannot propagate in the lattice with 4D speed more than the flipping speed c=lP/tP [really at particles creation and motion c√2, more see the link, but that isn’t essential here].
Some FLE flipping above along a direct 4D line can be caused by a practically infinitesimal P impact; but if P isn’t infinitesimal, that causes flipping FLE precession and corresponding propagation of the “FLE-flipping point” in the 4D space above along some 4D helix,
- i.e. causes creation of some close-loop algorithm that cyclically runs on FLE “hardware ” with the helix’s frequency ω, having momentum P=mc above, mis inertial mass, the helix radius is λ=λ/P;
- and the helix’s 4D “ axis” is always directed along P – particles are some “4D gyroscopes”.
The post is rather long already, so now
Sergey Shevchenko added a reply
So let’s continue about what is “special relativity”.
In the SS posts above it is pointed that everything that exists and happens in Matter is/are some disturbances in the Matter’s ultimate base – the (at least) [4+4+1]4D dense lattice of FLEs, which [lattice] is placed in the Matter’s fundamentally absolute, fundamentally flat, fundamentally continuous, and fundamentally “Cartesian”, spacetime,
- and that happens always in utmost universal “kinematical” Matter’s space with metrics (cτ,X,Y,Z), and corresponding spacetime with metrics (cτ,X,Y,Z ct), where ct is the real time dimension.
At that particles, most of which compose real bodies, at every time moment exist as “FLE –flipping point” that move along some4D helixes that have frequencies ω, having 4D momentums P=mc, m are inertial masses, a helix radius is λ=λ/P;
- and the helix’s 4D “ axis” is always directed along Pparticles are some “4D gyroscopes”.
So in Matter there exist two main types of particles – “T-particles”, which are created by momentums that are directed along the -axis [more generally – by 4D momentums cτ-components, but here that isn’t too essential], and so, if are at rest in the 3DXYZ space, move only along cτ-axis with the speed of light, and at that a T- particle’s algorithm ticks with maximal “own frequency”, the particle’s momentum is P0=m0c, where, correspondingly, m0 is the “rest mass”.
If a such T-particle, after some 3D space impact with a 3D space momentum p, moves also in 3D space with a velocity V, having 4D momentum P=P0+p, its speed along the cτ-axis decreases by the Pythagoras theorem in (1-V2/c2)1/2 , i.e. in reverse Lorentz factor,
- and, at that, despite that the helix’s frequency increases, the algorithm is “diluted by “blank” 3D space FLEs flips. So the “own frequency above” decreases in Lorentz factor, so the algorithm ticks slower; and so, say, moving clocks that are some algorithms as well, tick slower in Lorentz factor as well; if a particle algorithm has some defect, and so at every its tick it can break with some probability, so the particle is unstable and decay, such moving in 3D space particles live longer.
Nothing, of course, happens with time, there is no any the SR’s “time dilation”.
The post is rather long already, so now
Cheers
Roggers Waibi added a reply
As proposed by Albert Einstein, Special relativity fundamentally transforms our understanding of space, time, and the nature of reality. At its core, special relativity postulates two key principles: the constancy of the speed of light and the relativity of simultaneity. The former states that the speed of light in a vacuum is the same for all observers, regardless of their relative motion. This principle defies common intuition but has been rigorously confirmed by experiments. The latter principle, the relativity of simultaneity, suggests that events that appear simultaneous to one observer may not be simultaneous to another observer in relative motion. Special relativity introduces the concept of spacetime, wherein space and time are intertwined, and observers in relative motion will experience time dilation and length contraction effects. These phenomena have been validated through numerous experiments, such as the famous Michelson-Morley experiment and subsequent tests involving particle accelerators and high-speed particles. Special relativity forms the basis for modern physics, influencing fields ranging from particle physics to cosmology, and challenging our intuitive notions of space and time.
Christian Baumgarten added a reply
Article The Simplest Form of the Lorentz Transformations
Waibi's answer is correct. However, the postulates of SR do not generate understanding. The referenced paper provides evidence that the math underlying SR can mostly be obtained from Hamiltonian notions. Since Hamiltonian concepts are universal in dynamical systems, the mathematical relations of SR are universal as well.
Sergey Shevchenko added a reply
Rather detailed consideration of what the SR is see in series of SS posts in this thread sister https://www.researchgate.net/post/How_do_we_understand_special_relativity/2, pages 1,2;
So here only a few notes to
“…Special relativity introduces the concept of spacetime, wherein space and time are intertwined, and observers in relative motion will experience time dilation and length contraction effects. ..”
- really the concept of spacetime, wherein space and time are intertwined is fundamentally wrong.
Matter’s spacetime is fundamentally unique, fundamentally absolute, fundamentally flat, fundamentally continuous, and fundamentally “Cartesian”, ( [4+4+1]4D spacetime with metrics (at least) (cτ,X,Y,Z, g,w,e,s,ct), where all dimensions fundamentally are independent on each other; utmost universal – “kinematic” spacetime has metrics (cτ,X,Y,Z,ct),
- and, of course, fundamentally there cannot be any intertwining of any dimensions, any “time dilations”, “space contraction”, etc.
So that
“….These phenomena have been validated through numerous experiments, such as the famous Michelson-Morley experiment and subsequent tests involving particle accelerators and high-speed particles…
- really is quite incorrect. No any “intertwining” , “time dilations”, “space contraction” weren’t experimentally observed – that is fundamentally impossible. All what indeed is observed is/are real contraction of moving bodies lengths, slowing tick rates of moving clocks and intrinsic processes rates in unstable particles,
- but bodies aren’t “space” – though, of course are in space; clocks aren’t “time” though, of course tick in time, which [space and time] compose fundamentally only an empty container where everything in Matter exists and changes.
Though that
“….Special relativity forms the basis for modern physics, influencing fields ranging from particle physics to cosmology, and challenging our intuitive notions of space and time…”
- is essentially correct, since the SR is based on the indeed extremely mighty Galileo-Poincaré relativity principle; and so in everyday physical practice the fact that in the SR the relativity principle is absolutized up to absurd/illusory real interactions of particles, bodies, reference frames, etc., with space/time/spacetime is inessential. Again more see the pointed above SS posts in the linked sister thread.
Branko Mišković added a reply
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Opinion Article
Orientation in Space
Branko V. Miskovic
Independent Scientist, Novi Sad, Serbia
Abstract
The position, motion and acceleration of physical objects in the natural laws understand a relevant reference frame. In this sense, the two extreme solutions have been mutually confronted: an absolute cosmic frame or certain equivalence in a class of the frames at least. The imagined formal frames need be connected to evident material bodies. Owing to the complex mutual motions of all celestial bodies, none of them deserves a privileged status. Not only that the vacuum medium is inaccessible by instruments, but its nature and existence are questionable. On the other hand, even the limited equivalence of the formal frames, in the special relativity, does not obey some exceptional technical situations. A few restrictions of relativity in the mechanical and EM processes are here presented. As the synthesis of the two extreme theses, Mach understood a local orientation, in relation to the dominant material surroundings. In the technical practice, such a frame is connected to Earth. The astronomy and astronautics are tacitly referred to the local surroundings, just determined by nearby celestial bodies or their gravitations.
Aim: The solution of one of the crucial questions in physics.
Study design: Comparison and relation of known physical facts.
Methodology: Exhaustive reexamination of these relations.
Study duration: Throughout the author’s working life.
Results: Instead of the absolute or arbitrary orientation, the local preferential frames are finally affirmed and applied.
Keywords: Absolute, Relative, Local, Frame, Motion
Introduction
Physical laws describe the object interactions, in the form of the forces or energies determined by the kinematical quantities. The material bodies or particles, as the objects, represent the concentrated amounts of respective substantial quantities. The static, kinetic and dynamic forces are respectively determined by the positions, motions and accelerations of such objects [1,2]. The three mentioned kinematical quantities need be determined in a relevant reference frame, connected to an evident material body. With respect to the perpetual mutual motions, rotations and revolutions of all celestial bodies, the relevant reference is very questionable. Not only that such a frame is due to determine all the forces and energies, but also the object trajectories. Though theoretically simplest, the absolute reference frame has not been identified. At least approximately, the local technical orientation usually concerns Earth. Even after substitution of the terrestrial by solar orientation, it is not adequate in the wider cosmic space, out of the solar planetary system.
With respect to the limited former sights, the initial problem took the cosmological sense. Irrespective of the physical laws, a comparative body played the role of the cosmic center. In the first view, Earth seemed to be such a center. However, the paths of the other planets in this frame are extremely complex and illogical. Instead of the irregular planetary paths in relation to Earth, their concentric, circular or slightly elliptical orbits around Sun, obeying the three Keppler’s rules, were the bases for reliable formulation of the law of gravitation. On the other hand, such Moon’s orbit around Earth appears similarly complex in relation to Sun. Overlooking this fact, the traumatic transition from the narrower into wider references gave the impression of a great scientific revolution. In the final instance, none of these two references is applicable in the wider cosmic space, pointing to the predominant material surroundings, in the given spatial domain or respective level of observation.
A similar problem appeared in electrodynamics. Though the terrestrial orientation satisfies the usual technical practice, the reference of light propagation in the wider space is problematic. In the aim of confirmation of the expected absolute reference, connected to the rigid vacuum medium, Michelson made the known experiment, proposed by Maxwell. The difference of the two relative speeds of light in the longitudinal and transverse directions in relation to the orbiting Earth had been calculated in advance. However, the negative practical result pointed to the local preferential frame, connected to Earth. With respect to the traumatic Copernican U-turn, this fact has not been noticed nor emphasized. The later more accurate results, in amount of a few percent of the calculated value, have not been explained but are tacitly neglected or even forgotten by the time. Instead of the preferential local frames, the arbitraryorientation is proposed and imposed, as the provisory alternative at least.
In the absence of a unique reliable frame, the attention is paid to the mutual relations between two arbitrary frames, which needed equivalence is expressed by the principle of relativity. However, this principle is strictly satisfied by the static forces only, dependent on mutual distance of two interacting objects (Fig. 1), as the difference of their positions in the two frames. The kinetic force in Ampere’s law depends on the speed product [1], inexpressible by the relativity. Including one speed into the field expression, the relativity concerns mutual motion of the magnet and conductor. The dynamic forces, without the other explicit object, are especially problematic. The relativity must be thus restricted to uniform rectilinear motion. The obtained relations of the distances and times pushed back the orientation itself, and the geometrically expressed gravitation did not at all exceed the restrictions of relativity. The two unresolved problems are thus shadowed by the two useless theories.
Restricted Relativity
With implicit idea of relativity, Newton made the wellknown experiment for checking the needed frame equivalence. Rotating a container with water, he observed the radial forces manifest by the concave water surface. Comparing the stationary and transitional kinematical states, he reliably excluded the force dependence on the container rotation, but referred it to the undetermined wider surroundings. In the absence of the precise answer, he assumed a unique and rigid cosmic frame. Not being theoretically determined nor practically confirmed, this frame is the subject for the further reexamination.
Looking for a better solution, E. Mach asked the known double question. Would the water surface shape be influenced by the more massivecontainer, or even by the rotating cosmos? The former part suggested the hierarchy and fractional sum of more local frames, but latter one expected the equivalence of the two extreme frames, already denied by Newton. However, the known fact calls in question the former thesis at least. The forces acting on its satellites do not depend on the rotation of Earth, as the container carrying their orbits around Sun.
A similar result Faraday obtained in electrodynamics. Rotating a conducting disc in the front of cylindrical magnet, he noticed the kinetic induction [1] between the sliding contacts placed in the center and rim of the disc (Fig. 2). However, the magnet rotation was ineffective at all, so that the common rotation gave the same former result. Touching the magnet by the contacts directly, its conducting body took over the role of the disc, with the same induction. Alike the celestial case, this one does not satisfy the relativity. Unlike the former example, not strictly reconsidered, this one can be explained.
Figure 2. Faraday’s kinetic induction
The relativity here concerns the difference of the kinetic and dynamic inductions (1). The former of them is ascribed to the object motion (v) through the present magnetic field (B).
The speed of the causing electricity is implicitly contained in the field expression. On the other hand, the speed (U) of the field itself determines the dynamic induction.
v × B + B × U = (vU) × B (1)
However, the objects and domains of appearance of the two inductions essentially distinguish. Unlike the kinetic induction affecting the moving electricity only, dynamic one affects all the present electricity. Moreover, the former induction concerns all the object motion perpendicular to the field, but latter one is also conditioned by the field gradient [1]:
∇ × E = U · ∇B = – ∂B/∂t (2)
Figure 3. Kinetic and dynamic inductions
Figure 3 compares the two EM inductions. The current in the central conductor is followed by the circular magnetic field. The transverse motion of a parallel or perpendicular object conductor causes the kinetic induction. Such motion of the carrier, along the field gradient, causes the dynamic induction in the parallel objects only. In the transverse (or circular directions Fig. 2), the field gradient equals to naught. Similar relation may be ascribed to the gravitation on the celestial orbits. The field rotations transverse to their gradients are irrelevant.
Light Propagation
All waves, from the mechanical, via sound up to EM ones, as the medium disturbances, propagate at the speeds determined by the elasticity and inertia of respective media [1]. Unlike the former two waves, concerning matter consisting of the particles, the last wave type also propagates through the vacuum medium. Though not explain this medium, the waves demand its existence. The addition of matter, increasing the medium density, causes the slower propagation. The explanations of various physical forces [2] finally rely on respective media. Though light consists of photons, as the energetic particles, it propagates at the wave speed, determined by Maxwell’s relation (9b). The negation of vacuum medium – by special relativity, does not offer any other explanation of the above phenomena. The propagation of each disturbance is referred to the medium, irrespective of motion of passive observers or their instruments.
The same speed of light relative to the moving devices, or to their formal frames and passive observers, cannot be understood nor explained. Michelson’s result, just being referred to Earth, can be generalized to the other celestial bodies, but not at all to the arbitrary (inertial) frames. Apart from such the exaggerated generalization of the result, this opinion may be also conditioned by some cosmic relations [3]. Owing to the cosmic expansion, two bodies are mutually moving away at the speed (v) proportional with their distance. Despite this fact, the light starts from its emitter, propagates through space and arrives to the detector at the same speed (c) – relative to the local surroundings. In fact, it propagates accelerating in relation to both mentioned devices: from the speed c up to c + v, or from c – v up to c, respectively. The apparent difficulty is thus exceeded.
Doppler’s effects, at motion of the signal emitter or detector (3), respectively, strictly obey the frames connected to the local media. The ratios of the propagated and emitted frequencies – in the former, or of the detected and propagatedones – in latter cases, accord with the ratios of respective speed pairs [3]. If the two relative speeds, (c – u) & (c – v), were equal to the absolute one (c), these two effects could not arise. At common motion of the two devices, the two effects compensate each other, with the detected equal to emitted frequencies. The same result arises at opposite motion of the medium, irrespective of the propagation itself corrected for the medium speed.
wc/wu = c/(c – u) wv/wc = (c – v)/c (3)
However, at light propagating through running water Fizeau obtained the result (4), dependent on the factor k, as the ratio of the material and total field components [1,2]. Apart from the slower propagation, the frame is drawn in the direction (v) of the water flow, as the moving material stratum.
c = co/er + kv k = P/D = 1 – 1/er (4)
The similar Faraday’s effect, twisting the polarization of light propagating along magnetic field lines, is caused by circulation of the static (F), in the form of kinetic (A) potentials. The former of them plays the role of the moving stratum.
A = emVF ∇·A = – em∂F/∂t (5)
The factor of the frame draw in the cosmic space may be similarly determined. Apart from the slower propagation in the present gravitation, the frame draw is determined by the ratio of the moving and dominant potentials.
Though applied in practice, the direct negation of the arbitrary orientation by Sagnac’s effect is ignored in the theory. Namely, two opposite light beams, propagating along the perimeter of a rotating figure, give the evident phase difference, according to the different relative speeds of light. This effect is multiplied by application of a solenoidal light conductor, instead of the figure perimeter. Such device is applied for registration of the angular airplane deviation, instead of the mechanical gyroscope. The references of the observer, in a resting laboratory or the rotating airplane, do not at all influence the result. This practical argument exceeds all the alleged relativistic proofs.
Transformations
The kinetic and dynamic inductions (1) added to the central static field [1] give the summary field around a moving charge (6). The longitudinal speed (V= v) of electric, and transverse (U) – of magnetic fields, obey the principle of relativity [1]. Alike the static field – at rest (E), the summary result (E’) is also centrally symmetric, tending to naught approaching the speed of light propagation. Apart from the magnetic field not affecting resting objects, the axial dynamic induction – subtracted from the radial static field, gives the ellipsoidal result.
E’ = E + (vU) × B = (1 – emu2)E (6)
Missing the dynamic induction or understanding the object-field motion (u= vU), H. A Lorentz formulated the summary force (7a). Expecting the similar and paralel magnetic phenomena [1], the symmetric magnetic relation was understood (7b), with the opposite mutual motion of magnetic poles and electric field. In fact, these two equations express the same relations, with the two equal and opposite mutual speeds. Not only that the free magnetic poles do not exist [1], but the field actions on the magnetic moments are essentially distinct. Apart from the former conditionalequation, latter one is fictional.
E’ = E + u × B B’ = B + emE × u (7)
The inverted set (8,9) exchanges the causes and effects. The opposite motion of the frame is understood. The set determinant (8b), as the factor (6) restricted to the transverse plane, points to the privileged frame, connected to the medium. For the sake of the frame equivalence adopted in advance, this value is arbitrarily distributed between the two sets: by 1/g in each of them. The formal inversion only is thus kept.
E = (E’ – u × B’)/g2 g2= 1 – emu2 (8)
B = (B’ – emE’× u)/g2 em = 1/c2 (9)
This action implies the explicit negation of vacuum medium at least. To push back the media, the product of the two constants is usually substituted by the speed c (9b).
By the factor distribution, the transverse field components (7) are arbitrarily increased, calling in question the mathematical form of Maxwell’s equations. Owing to their huge authority, the problem has been avoided by the complementary deformations of the two remaining 4D axes, longitudinal and temporalones!! (10). The former relation divides the position transformation (Fig. 4) by the factor g less from unit, but latter one also transforms the time. Owing to the limited relativity, these transformations are restricted to the uniform rectilinear speed u, in relation to the still unknown relevant reference frame!
x’ = (xut)/g t’ = (tux/c2)/ g (10)
Figure 4. The position transformation
The equations (10) somehow distinguish lengths and times in the two frames, depending on their mutual motion. Not only that this dependence cannot be physically explained, but lengths and times would depend on the speed, as their ratio! Moreover, the lengths depend on a given time beginning, as well as times – on the adopted frame position. Unlike the time possibly calculated from the frame overlap, the position of a chosen frame cannot be referred to any privileged location. The relative time, dependent on the object position – in the arbitrary frame, is undetermined!! Not only that the reference frames are arbitrary, but represent the mere mental constructs. There is not any logic by which their mutual motion can influence lengths and times, irrespective of any motion of the passive observers.
The ratio of the two equations (10) gives the relativistic speed transformation (11). Here v & v’ denote the object speeds in the two frames, and u – their mutual motion. The usual speed difference is here divided by the nominator less from unit, thus being artificially increased. Applied to light – as the object, this equation turns into the identity: c’ = c. Following through the sequence of inconsistencies, this is the pretext for the same speed of light at all (inertial) frames. This opinion is here already denied by the sequence of empirical facts.
v’ = x’/t’ = (vu)/(1 – vu/c2) (11)
Avoiding or exceeding all these speculations, Hobble’s ratio of the distance and speed at the mutual motion away of two celestial bodies just understands the unique cosmic time. Some local times, deviating from the absolute one, are theoretically inconceivable and practically impossible. The real transformation of the position (Fig. 4), concerning the absolute time, is the only acceptable alternative. Namely, the positions of an object in the two frames differ no more or less but for the mutual distance covered after the initial frame overlap. In the unique space and time, this is the only reasonable relation.
General Relativity
Despite the sequence of formal inconsistencies above clearly presented, the restriction to a uniform rectilinear motion is the unique declared difficulty of special relativity. Alike inertia being generalized to the force action, Einstein tried to generalize his special to general theories. After some wander through chaotic speculations, he lost from view the initial problem. Owing to the kinetic and dynamic forces out of relativity, he returned to the static laws. On the basis of their possible balance, inertia is reduced to gravitation!? The radial field around a body is copied into the super-spherical space, along t-axis.
Alike gravitation projected on a slope, it itself is thus treated as the similar projection of some super-force acting from the cosmic center (Fig. 5). The field around a body is illustrated by the spatial curvature, as the local deformation of space, in the form of the funnel. At the interstellar space of the regular spatial curvature, such the projection equals to naught.
Figure 5. Local and global curvatures
Without any valid criteria, this concept is widely taken as the theory of gravitation. In the equivalent form, it speaks nothing about the essence of gravitation, but only further mystifies this phenomenon. If the formal mistakes and/or inconsistencies be excluded, there is no any reason by which its results will differ from the classical ones. At least accidentally, this analogy announces the radial cosmic expansion along temporal axis [3], irrespective of the red shift lately noticed.
Albert Einstein
In these times failing in the authorities of any kind, Einstein is an unquestionable scientific authority, if not in general, then in the modern physics at least. Instead of the resort to the praise, a brief and unbiased, as much as possible adequate valorization of his scientific contributions need be here presented. Avoiding unnecessary repetitions, the arguments rely on the above text and its references, also having in view the scientific criteria. Unlike majority of the other scientists, being famous concerning their unquestionable contributions, Einstein is celebrated with respect to his controversial views.
Apart from the photo-electric effect, Einstein deserved the leading position by the three ideas at least: the fourth dimension, curvilinear space and equation: w = mc2. Although the former two ideas were not originally his, Einstein emphasized and affirmed them self-confidentially. The indirect and complicated derivation of his equation seems to be accidental, resulted from the random formal procedures. Apart from the considerable simplification of this derivation, a direct its inference has been also presented in [2]. Not only that this equation is thus affirmed, but its convincing interpretation is finally enabled.
Unfortunately, none of the three mentioned ideas or results had been fully elaborated and applied by Einstein. At least in principle, the fourth axis is directly colliding with relative time. According to the tensor form of Maxwell’s equations [1], time is a real metrical axis. The probable restriction of the medium of light to the spatial gravitation excludes its temporal propagation. The relative time calls in questions its physical sense and reality. Not only that this concept is fantastic and arbitrary, but cannot be argued by any physical reason. At least some of its contradictions are here already clearly presented.
The idea of curvilinear cosmic space has been also unfinished. Though the Riemannian frame excludes the surrounding cosmic background [3], the modern cosmologists understand it. Even the surrounding cosmoses are expected in the background thus tacitly predicted. This inconsistency of the followers, not trying to finalize Einstein’s principal ideas, may be understood: the famous authorities would not make logical mistakes or give incomplete ideas. His equation has not been interpreted so far. Instead of its undefined application, it can be ascribed to the massive particles, unlike similar Plank’s relation for photons.
At least a part of Einstein’s fame relies on the arbitrary spatial orientation, as the main his failure. It implies the same speeds of light at all so called inertial reference frames, declared equivalent by the principle of relativity. Without sufficient vision of physical processes, as the corrective criterion, the formal calculations are prone to various mistakes or inconsistencies. In the final instance, the relativities of lengths and times are unacceptable at all. As the needed condition for these views, the vacuum medium had been explicitly negated. Imposed by the authority, this view still hinders the further development.
Let us also emphasize some Einstein’s methodological errors, mainly reducible to typical inconsistencies. Such is the arbitrary substitution of two similar math expressions by their geometric average. The average of two Doppler’s effects he applied to the cosmic red shift of light [3]. The opposite signs in the two field tensors he substituted by the imaginary unit [1]. In the opposite sense, the set determinant (8b) has been distributed between the two sets. The parallel EM phenomena (7b) were already understood. By the explicit negation of the medium, Einstein imposed the kinematical relativity.
The incomplete or doubtful principal views may be added. Apart from the static interactions, the relativity can be applied to the special cases of some distinct forces. Concerning two Mach’s ideas, Einstein chose the frame equivalence as the worst one. The unexplained kinetic induction was neglected. The lengths and times dependent on the moving observers fail in any explanation. The dependence of the relative time on the adopted spatial frame has not been noticed even by the numerous opponents!? The wide acceptance of relativity is not strictly founded, but imposed in the absence of the competent critiques.
By mess of the notions, Einstein confused the opponents. He substituted the two EM constants by the abstract speed of light, thus pushing back a vacuum medium at least. The absolute light propagation through the medium, irrespective of the instruments and observers, he substituted by the invariant relative speed. The temporal cosmic process, independent of the transverse spatial motion [3], he ascribed to the light propagation in a given spatial direction. The same speeds of light in the local cosmic situations imposed the additional confusion. All these facts taken together made the full mess in the theory.
Substitution of some theses is also frequent. The ellipsoidal electric field deformation around a moving charge, caused by the longitudinal dynamic induction [1], he ascribed to the increased transverse fields, by distribution of the factor g. The incomplete medium draw by the running water he ascribed to the relativistic speed transformation. Instead of the stronger structural stability, the shorter lives of speedy mesons are ascribed to the relative time. The two former cases at least do not obey the numerical relations. In the final instance, there cannot be even enumerate all Einstein’s inconsistencies.
Results
The relativity, as a postulate, is valid for the static forces only. Owing to various reasons, it cannot be applied to the kinetic and dynamic processes. The relativities of distinct physical forces are restricted to the special technical situations.
The same speed of light in a class of the frames, implied by the relativity principle and additional inconsistencies, cannot be anyhow understood nor explained. The generalization of the local to arbitrary orientation is exaggerated.
A sequence of the wave effects somehow contradicts to the relativistic views. At least one of them directly denies the arbitrary orientation of light. The navigational system (GPS) could not take into account the relativistic views.
The relativistic transformations are founded on the sequence of theoretical mistakes and inconsistencies. The dependence of the relative time on the adopted spatial frame is especially unacceptable and must be refuted forever.
Imposing relativity of lengths and times, the special theory lost from view the orientation. Reducing gravitation to geometry, the general theory did not generalize special one. These two theories only mystify the physical relations.
Not only that the restriction to so called inertial frames has not been exceeded, but its definition understands in advance a relevant reference frame. Going into the opposite direction, this opinion terminates in the local orientation.
Starting from the unique (absolute) reference – as the thesis, and arbitrary orientation – as antithesis, Mach’s local orientation in relation to the predominant material surroundings – as the synthesis, satisfies all the practical situations.
Conclusion
Between Earth and Sun, Copernicus chose the latter referent body. Newton similarly preferred the wider surroundings to the water container. Amongst the two Mach’s theses, of the local or arbitrary orientation, Einstein took the latter one. Not only that the orientation is thus overlooked, but disabled. The remaining local orientation, relative to a dominant mass, with some draw of the frame by other masses, satisfies all the practical situations. Although the rotation of Earth does not influence the satellites, its revolution firmly carries their orbits around Sun.
References
1. Miskovic BV. Foundation of Electrodynamics. Int J Phys Stud Res. 2023; 4(1): 98-103. doi: 10.18689/ijpsr-1000116
2. Miskovic BV. Unity of Physics. Int J of Theor and Math Physics. 2024; 2(1).
3. Miskovic BV. Curvilinear Cosmology. Int J Cosmol Astron Astrophysics. 2023; 5(2): 231-236. doi: 10.18689/ijcaa-1000143
4. Mišković B. A Brief Review of Special Relativity. Int J of Theor and Math Physics. 2019; 9(2): 36-40. doi: 10.5923/j.ijtmp-20190902.02
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This discussion dives deep into contrasting perspectives on fundamental physics theories, particularly special relativity. Here's a breakdown of the main points raised:
1. **Quantum FFF Model Differences**: The Quantum FFF Theory differs from the standard model in several key aspects, including the nature of fermions, the vacuum structure, and the concept of consciousness in particles.
2. **Critique of Einstein's Special Relativity**: Fred-Rick Schermer presents a critique of Einstein's approach, arguing that Einstein's reliance on spacetime as the explanatory framework neglects the behavior of matter itself. He uses an analogy of mice in a cage to illustrate his point, suggesting that Einstein attributed too much agency to spacetime rather than matter.
3. **Response on Vacuum Energy**: Wolfgang Konle defends Richard Feynman's idea of vacuum energy, proposing that the additional energy density could be used to recycle star fuel from black holes, although this idea may seem initially counterintuitive.
4. **Fundamental Postulates of Special Relativity**: Sergey Shevchenko elaborates on the postulates of special relativity, particularly emphasizing the Galileo-Poincaré relativity principle. He suggests that the fundamental flaws of special relativity only reveal themselves on a fundamental level, while in everyday physical practice, the theory aligns with reality.
5. **Clarification of Fundamental Phenomena**: Sergey Shevchenko further delves into the clarification of fundamental phenomena such as space, time, energy, information, and matter, advocating for a philosophical and scientific framework that considers these concepts in the context of informational patterns and systems.
Overall, the discussion highlights diverse perspectives on the interpretation and understanding of special relativity, touching on issues of fundamental principles, theoretical frameworks, and philosophical underpinnings.
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Hi.
I am currently validating a measure on public mental illness stigma in the workforce , and have found a relatively high correlation between the two constructs: “work-related beliefs/competency” and “responsibility for having a mental illness“ and also the two constructs “work-related beliefs/competency” and “perceptions of dangerousness and unpredictability“
I am probably just not good enough to search or smart enough, but I cannot find any previous research on this relationship or any theories that can help me explain my explain this relationship. Anyone who can be off assistance?
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Thank you, Stephen :) I have looked into that article previously, but it does not necessarily help explaining this relationship.
Thank you, Abhinshek :)
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What is the minimal education competency for use of insulin engineered safety needles
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The minimal education competency for the use of insulin engineered safety needles would typically include:
A basic understanding of diabetes and its management, including the role of insulin in glucose regulation.
Knowledge of the different types of insulin delivery methods, including syringes, pens, and pumps.
Understanding of the importance of proper needle technique and safety precautions when administering insulin injections.
Familiarity with the engineered safety needles, including their design and functionality.
Ability to properly assemble and dispose of the needles, as well as troubleshoot any issues that may arise.
Understanding of the proper storage and handling of insulin and needles.
Ability to recognize and respond to signs of hypoglycemia and hyperglycemia.
Knowledge of the appropriate dosing and administration guidelines for insulin, including the timing and frequency of injections.
Familiarity with the patient's individualized insulin regimen and any adjustments that may need to be made based on their specific needs.
Ability to communicate effectively with the patient and other healthcare professionals regarding the patient's insulin therapy.
It's important to note that the specific competencies required may vary depending on the individual patient's needs and the healthcare setting in which the insulin is being administered. It's important for healthcare professionals to receive ongoing education and training to ensure they are up-to-date on the latest advancements in insulin delivery methods and safety protocols.
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Dear research community,
I would like to move forward with a toy startup based in South Australia or the Northern Territory and am looking for a potential co-founder with industrial design competencies.
Since the startup should be essentially based on utilising research principles, I would prefer co-founders from the academic community.
Please let me know if you are interested or have any tips.
Thanks and best,
Tim
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Are you still on the lookout for someone to work alongside your research capabilities?
Regards.
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I am writing to let you know that Journal of E-Learning And Knowledge Society (SCOPUS Q2, SJR Q3) is currently welcoming submissions of original research to "VOLUME 20 | SPECIAL ISSUE CALL 2024" with title “Digital Transformation in Educational Research: Competencies, Resources and Challenges in the Context of ICT”. As the Guest Editor of this CfP, I hope you will consider this as an outlet for a future research paper.
As a result of these reflections, different questions arise.
• Are teachers digitally trained in research skills?
• What skills do teachers have to use digital resources developed for the research context?
• What factors influence the digital competencies of teachers in their research work?
• How do AI tools impact the digital skills of teachers in research work?
For this reason, we welcome studies that cover topics related to:
• digital skills in research work;
• analysis of the use of digital resources and AI tools for the research process;
• factors incident to the digital competencies associated with the research process;
• infrastructure of university institutions on digital resources for the research process.
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Dear Prof. Guillen - Gamez!
I appreciate your time and effort to inform our community about this opportunity. The topic is of critical importance:
The European Commission, 2024. Digital learning and ICT in education, available at: https://digital-strategy.ec.europa.eu/en/policies/digital-learning
Yours sincerely, Bulcsu Szekely
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What do you do if your educational technology startup is struggling to compete in today's market?
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I would advise you to consider a Blue Ocean Strategy. In particular, I would start with the Strategy Canvas and Eliminate-Reduce-Raise-Create (ERRC) Grid. Good luck, it is a crowded space.
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Cities compete with each other in a globalised environment. How does this affect the design of urban space and the community?
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The design of tourism-focused public spaces can have various impacts on local communities, both positive and negative. Here are some ways in which it can affect them:
  1. Economic Impact: Well-designed tourism-focused public spaces can stimulate economic activity by attracting visitors, leading to increased spending in local businesses such as restaurants, shops, and accommodations. This can create jobs and generate revenue for the local community.
  2. Cultural Exchange: Tourism-focused public spaces provide opportunities for cultural exchange between locals and visitors. They can showcase local traditions, arts, and crafts, allowing residents to share their heritage with tourists and vice versa. This cultural exchange can foster mutual understanding and appreciation.
  3. Community Identity: The design of public spaces can reflect the identity and values of the local community. By incorporating elements of local history, architecture, and culture, these spaces can strengthen community pride and identity. However, if the design overly caters to tourists and neglects local preferences, it may lead to resentment or loss of identity among residents.
  4. Social Interaction: Well-designed public spaces can serve as gathering places for both locals and tourists, fostering social interaction and community cohesion. They provide opportunities for people to meet, socialize, and participate in collective activities, contributing to a sense of belonging and connectedness.
  5. Environmental Impact: The design of tourism-focused public spaces can have environmental implications, particularly in terms of resource use, waste generation, and ecological conservation. Sustainable design practices, such as green infrastructure, energy-efficient lighting, and waste management systems, can minimize negative environmental impacts and promote long-term sustainability.
  6. Infrastructure Development: The development of tourism-focused public spaces often requires infrastructure investments, such as transportation, utilities, and amenities. While this can improve the quality of life for residents by providing better access to services and facilities, it may also lead to gentrification, displacement, or unequal distribution of resources if not managed properly.
  7. Overcrowding and Congestion: Popular tourism-focused public spaces may experience overcrowding and congestion, especially during peak tourist seasons. This can put pressure on local infrastructure, increase traffic congestion, and disrupt the daily lives of residents. Proper management strategies, such as crowd control measures and visitor management plans, are necessary to mitigate these issues.
Overall, the design of tourism-focused public spaces can significantly influence the well-being, economy, and social fabric of local communities. It is essential to consider the needs, preferences, and concerns of residents while planning and designing these spaces to ensure that they benefit both locals and visitors alike.
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Colleagues #question, or rather three questions that have been tormenting me for many months and even preventing me from sleeping. Maybe you can answer them:
#1. Do creative people (artists, writers, sculptors, etc.) have entrepreneurial competencies?
#2. Do they need them or not in their professional career?
#3. Do they use them or not? The answers are simple: 1-yes or no, 2-yes or no, 3-yes or no. Can you please answer, it’s very, very important.
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Yes at the same time. Dealings in art is the most likely way for artists to make sufficient money. So if they don’t have a management company, then they suffer organizing all their projects and also fall prey to bad dealings simply because there’s so much on their plate. Creative people need space to think and process their own information and their carefree expression. That’s why you need the manager so they focus on all the business and then you as the artist just focus on the making art.
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Why contemporary art business conditions should change the meaning/importance of entrepreneurial competences?
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Contemporary art business conditions may require a different approach to business competencies due to the changing nature of the art market, including digitalization, globalization and new forms of cultural consumption. This may mean that contemporary art professionals need tailored business skills to take advantage of emerging opportunities, manage the marketing of artworks effectively and navigate an increasingly complex and competitive market. In summary, changing business conditions in contemporary art may influence the meaning and importance of business competencies by requiring continuous adaptation and evolution to succeed in the field.
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"I am conducting advanced research to determine the extent of the influence of a church leader's competence on religious moderation."
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As with most things in life, being competent in a field of practice gives the practitioner a good edge compared to those without a clue or experience. Competence in a sense doesn't need to be at the skill level but can also be at the Character level. Having goof morals can be a qualifying factor where the skills lack or in a field where that is more important than education.
When it comes to religious moderation. Being level headed, not easily angered, being sensible, patience, and the rest of the virtues can pass as competence for the leader.
In urban areas, having a good education will boost the Church leader's profile and make them 'believable' in situations where one needs to mediate between two city dwellers. Education in this sense with be considered a necessity for competency and will also improve the confidence levels of the leader. Many uneducated leaders unfortunately succumb to low esteem and but then tend to be overly religious. Many decisions are then based on a spiritual 'high' or influence rather than common sense. This unfortunately will lead to radicalisation which is one of the biggest hindrances to religious moderation.
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Are current scientific views propped up by censorship of competing ideas and mutual complacency?
I am asking this controversial question because I cannot get a single astronomer, physicist, cosmologist, or astrophysicist to take the other side of my arguments.
I hope some of the outstanding scientists here will accept to talk shop.
I made a special request to Dr. Brian Keating.
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Yes Marco Pereira to your question. However, I prefer to understand such academic selection (filter) mechanisms mainly as a human phenomenon of social group psychology, which also applies to the history of exact sciences.
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An expert is a person who has made all the mistakes that can be made in a very narrow field. Niels Bohr
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I am looking for study participants who are instructional designers, business faculty, and business experts.
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Salute for coming up this study, may I respectfully ask you if what will be our role in the development of your study? What's the design of your study? Details please. Thank you for the invitation.
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I need more clarity on the question.
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Hello Umar, I believe there are many answers to your question, depending on your classroom/teaching/grade level. For example, here in the US, we have many "inclusion" classes in the sciences, which means that students of all academic levels can be in the same class. However, in such situations, learning is always enhanced by the presence of teacher's aides, or para-professionals. There is no doubt that students with low literacy need special help in the sciences.
One thing that is difficult is the science vocabulary; in biology for example, in one academic year, I counted well over 150 new words/names/phrases that were seen in both lessons and exams. Being prepared for this, was essential.
I also noticed that the more hands on labs and such that could be done in class, the less literacy played a factor. There is no doubt that they can definitely achieve competency, as noted in the response above. The real test of this of course would be, "Are such individuals going to be prepared to seek an occupation in science?"
Your areas of instruction, as listed with your name, will be one key to the future for such individuals.
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Dear colleague, I am looking for assessment tools for Military Leadership Style and Competences. However, I am finding difficult to get information on the same. Can anyone help me?
Thanks in anticipation.
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Mr. DAVID, thank you for your your insightful comments. I am also engaged in research and development in military leadership and organizational development. As, I could understand in past one decade that the behavior, actions and practices in armed forces are quite different from the civil population. Military is more than a profession, it is a way of leading life and thus, I am afraid of generalization of the test development and validated on civil population to armed forces.
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What is representational competence in physics?
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There is no consensus in science and research, regarding representational competence (RC) as a unified theoretical framework. RC is essential for the acquisition of conceptual understanding in physics. It enables the interpretation of diagrams, graphs, and mathematical equations, and relating these to one another as well as to observations and experimental outcomes;
success in solving physics problems is related to the representational format of the problem. In this sense, Alwielland Q. Bello RC can indeed be understood as the competence to mentally represent a physics problem or generally physics theories by simple cognitive models, mainly via visualization (simple model by combining simple human language, logic and math).
A theory
has, only the alternative
of being right or wrong.
A model has a third possibility: it
may be right, but irrelevant.
Manfred Eigen
All models are approximations. Essentially, all models are
wrong, but some are useful. However, the approximate nature of the model must always be borne in mind.
George Box
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How do creative and critical thinking affects the development of 21st-century competencies?
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Interesting question and reply.
Indeed creativity in education is important. After all, since access to knowledge is becoming easier, education should focus on providing qualities for innovation and development of new knowledge.
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Hi, I have to perform a ligation reaction between a PCR fragment and a plasmid, in order to transform competent E. coli strain to amplify the plasmid. I will also make a gel to check the correct size of the plasmid+insert.
Is it possible to purify the plasmid DNA with a kit from the reaction where I performed the ligation reaction, and then transform my E. coli cells, or I have to purify it from the gel? I would like to skip the step of purification of the plasmid from the gel, if possible.
Thank you for your help.
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If using chemical transformation you can just use the ligation mix directly. To visualize a ligation on a gel requires large quantities of both vector and insert.
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Dear colleagues,
According to the International Code of Zoological Nomenclature (Chapter 12, Article 60, especially 60.3 entitled "Junior homonyms without synonyms"), the substitutes for homonymous names lacking valid synonyms, are designated with the new “author name” and a “new date”
A representative example is the following paper:
Kittel, R.N. 2016. Eighty-nine Replacement Names for Braconidae and Ichneumonidae (Insecta: Hymenoptera: Ichneumonoidea). Japanese Journal of Systematic Entomology, 22 (2): 161–174.
I believe this approach is not logical. Those who describe a new taxon, such as a genus or species, invest considerable effort in specimen collection, taxon study, proving the novelty of the taxon, taxon description, illustration, identification key, and distinguishing it from closely related taxa. Moreover, during the 18th, 19th, and early 20th centuries, communication systems and the availability of scientific publications were not as advanced as they are today. Therefore, some of the scientific names become homonymous, especially at the species level.
Article 60.3 of the International Code of Zoological Nomenclature (https://www.iczn.org/the-code/the-code-online) is as follows:
60.3. Junior homonyms without synonyms
If the rejected junior homonym has no known available and potentially valid synonym it must be replaced by a new substitute name, with its own author and date; this name will then compete for priority with any synonym recognized later.
It simply dedicated an authorship to someone who simply suggested the new name. Do you find this article logical?
What is your opinion on this matter?
Kind regards,
Ali Asghar Talebi
p.s.: I mentioned Dr. Kittel's paper as an example, and I know that she is a distinguished expert on the systematic of Ichneumonoidea.
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In European Chrysidoidea only a few species have been renamed in this way, usually after the original genus was synonymised according to modern insights. A more unsatisfactory situation are several detailed descriptions of newly discovered species, of which the author assumed it had been already described. These descriptions are rejected by the code because no new name was published. This will encourage authors to publish any specimen that is not recognised as a new species, without investing time in extensive research.
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As there is globalisation and the digital revolution in every aspect of future learners who are so-called new millennium learners, how the Innovative Learning Environments fulfil the purpose. Also, there is a need to look into the well-being of the learners and how the pedagogy and curriculum can be designed for the community needs of every learner.
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I agree Babu (the unsuitability in all countries of old style LMSs are also a problem. I think the best we can do is design for uncertainty,sustainability and flexibility in education.
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If you are a teacher/educator/instructor, please answer or share this question.
Are there any specific characteristics or competencies that you truly love to obtain?
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As a teacher, I would like to develop advanced soft skills and continuous professional development, as well would like to learn new teaching and learning methods and innovative methods of teaching. I know in the future time AI will play a vital role in all sectors including education so try to maintain human pace with AI.
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Greetings, fellow researchers and industry enthusiasts,
Are you intrigued by the potential of Skill-Based NFTs in revolutionizing industries? I'm passionate about exploring this transformative concept and seeking like-minded collaborators to dive into its possibilities.
My Expertise: I specialize in Blockchain Development, Industry Insight, Tokenomics and Economics, AI and Data Science, Legal and Compliance, User Experience (UX) and Design, Collaboration and Project Management and hold PhD in Computer Engineering. I'm driven to innovate and leverage Skill-Based NFTs to elevate industries through cutting-edge technology.
The Vision: Imagine a future where industries harness the power of NFTs to represent skills, competencies, and professional achievements. I'm eager to assemble a collaborative team to explore and develop this vision further.
Collaboration Opportunities: I'm open to various collaboration avenues, such as: • Joint research initiatives • Co-creating innovative NFT solutions • Sharing insights, resources, and expertise • Mentorship and support for passionate individuals in this realm
Get in Touch: If you're engaged in NFTs, industry transformation, or simply excited about shaping the future of skills representation, let's connect! Reach out to me at henry@elu.nl to explore potential collaborations or discuss ideas.
Let's unite our expertise, ignite innovation, and create impactful Skill-Based NFT solutions for industries. I'm eager to embark on this journey together.
Warm regards,
Henry Ukwu, PhD
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The topic is interesting
I am honored to join for any research collaboration with you
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My scrutinizing the literature on MS for decades failed to spot any concrete archetypal or milestone documents or the results of some topical statistical investigation that might support at least one of the repeatedly updated clinical definitions of the disease.
Isn't there some expert in neurology, neuropathology, or the history or philosophy of medicine who feels competent to explain, even lend some helping hand for overcoming, this conceptual deficit?
What justifies the characterization of MS in terms of neurological disorders being disseminated in space and in time?
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Searching for a Direct Route to Multiple Sclerosis Treatment
Researchers created a new high-throughput tool to hunt for therapies that remyelinate the nervous system...
"In MS, a patient’s immune system mistakenly attacks the myelin sheath. Inflammation damages the neurons left vulnerable by demyelination, and causes a range of symptoms, including vision loss, muscle weakness and dysfunction, and sensory changes. Current MS therapies target the immune system to slow disease progression, but scientists seek a more direct therapeutic approach. “Just by stopping the immune system, you can’t recover the myelin that’s degraded,” explained Xitiz Chamling, a neuroscientist at Johns Hopkins University. “There is a huge interest in this field to re-establish myelin, which is called remyelination.” This interest stems from the potential to cure or reverse the disease with treatments that promote myelination by oligodendrocytes...""
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Dear colleaques
I have a problem with cloning of my PCR product (829 bp) into pET101 TOPO vector (5753 bp) by Invitrogen™ Champion™ pET101 Directional TOPO™ Expression Kit. I performed a PCR reaction to obtain my product, which I purified from the gel. The forward primer contains the CACC sequence as recommended. For PCR reaction I use Phusion Plus DNA polymerase whitch generates blunt ends. I got strong band with corect size and purified my DNA by Nucleospin kit. The concentration of my PCR product was 35,2 ng/ul.
For cloning reaction I follow the instructions in manual. It is important to use 0,5:1 to 2:1 molar ratio of PCR product:TOPO vector. So if I used 1 ul of vector (15-20 ng) I dilute my PCR product to concentration 3,52 ng/ul and add 0,82 ul of them into the cloning reaction (molar ratio 1:1) and incubated for 5 min (first time and 20 min second time with the same results). As control I used reaction only with vector (without PCR product). With reactions I transform One Shot TOP10 Chemically Competent E. coli and incubated on the agar plates with ampicilin (100ug/ml) owernight at 37°C. But the results were the same on both plates, where I got hundreds of colonies.
Then I took some 20 colonies and used them as templat in control PCR wth the same primers which I used at the beginning of the process. Reasults were negativ. This was also confirmed by restriction analysis after DNA isolation (miniprep).
Where could be mistake? Thank you very much for any advice.
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Thank you very much Robert Adolf Brinzer
I mean that this kit with topoisomerasaI needs PCR product with blunt ends, without A-tailing.
Patrik
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related studies and literature
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  • UNESCO and IFAD. (2016). Learning knowledge and skills for agriculture to improve rural livelihoods1.
  • Lybaert, C., Debruyne, L., Kyndt, E., & Marchand, F. (2022). Competencies for Agricultural Advisors in Innovation Support. Sustainability, 14(1), 1822.
  • Ouma, G., Awuor, F., & Kyalo, G. (2016). Assessment of Knowledge and Competences in Agricultural Engineering Acquired by the Senior Secondary School Students for Farm Mechanisation. Journal of Education and Practice, 6(10), 513.
  • Mwangi, J. W., & Nyaga, C. K. (2018). Influence of instructional resources in learning agriculture in secondary school on employment creation in Vihiga County, Kenya. International Journal of Educational Administration and Policy Studies, 10(1), 1-94.
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May I get some recommendations and Literature?
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Да конечно
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So I am currently titrating a ligand (A, 12 µM) which is a dimer (in syringe) to a monomeric protein in cell (B, 61 µM). The experimental conditions are 20 mM Sodium Phosphate, 100 mM NaCl, and 2 mM TCEP at 20 C. I observe reasonable heat change after titration but the stoichiometry is consistently lower than 1. Though on the literature, I have observed a N~1 for the same binding proteins (though the titrations are done in reverse orientation).
I believe it is due to the low C value that I am not observing a sigmoidal binding curve. Unfortunately, I am limited by protein and can not further increase the concentration without precipitation of my protein. the
Would a low N value mean only a fraction of my protein in the cell are binding competent/active? If so is there any way to diagnose using any other method and correct it? Below are the attached thermograms and binding isotherm for more clarity.
Thank you.
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The numbers for the concentrations in your text do not agree with those observed in the figure.
Since the ligand is a dimer, would the dimer bind one single molecule of the other protein, or two?
When dealing with dimeric proteins, I always recommend, if possible, to perform the assay with the dimeric protein in the cell, to avoid additional problems.
If you have information about that interaction in a certain experimental scheme, I would recommend following the same experimental scheme. After you reproduce the known behavior, then you can explore other possibilities.
Regarding the c-value: c-value is not a goal in itself. Forget about pursuing a high enough c-value guaranteeing a sigmoidal isotherm. Very often it is not achievable (low affinity), and very often it is not necessary for an experiment to be considered good (there are many other features people pay little attention that are even more important than the c-value).
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What is entrepreneurship competence for people? Can we build a entreprenuership competence framework for people, for students? Can we train this competecnce for students?
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Entrepreneurship competence for students in today's world is a vital skill set that goes beyond traditional academic knowledge. It encompasses a combination of skills, attitudes, and knowledge that empower students to identify opportunities, take calculated risks, and create innovative solutions in the dynamic global business landscape.
First and foremost, students need a deep understanding of their chosen industry or field, including market trends, customer needs, and potential competitors. This knowledge forms the foundation for informed decision-making. Additionally, entrepreneurial competence involves developing critical thinking and problem-solving abilities to navigate complex challenges.
Adaptability and resilience are essential traits for aspiring entrepreneurs. The ability to pivot and learn from failure is crucial in an ever-changing business environment. Effective communication and teamwork are also vital, as entrepreneurs often need to collaborate with diverse stakeholders, including investors, partners, and customers. Financial literacy and risk management skills help students make sound financial decisions and manage resources effectively. Furthermore, creativity and innovation drive the development of unique products or services. Finally, an entrepreneurial mindset involves a willingness to take initiative, a passion for learning, and the ability to network and seek opportunities. In summary, entrepreneurship competence for students equips them with a holistic skill set that empowers them to identify, create, and seize opportunities, fostering innovation and economic growth in an increasingly competitive world.
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  1. Observational Analysis: Researchers observe and record conversations to study how individuals from diverse linguistic backgrounds interact.
  2. Transcription: Spoken language is transcribed into written form for detailed analysis, including pronunciation, intonation, and pauses.
  3. Coding and Categorization: Linguistic patterns and sociolinguistic variables are identified in transcripts, such as code-switching and language choices.
  4. Quantitative Analysis: Statistical techniques may quantify sociolinguistic phenomena like code-switching frequency or linguistic feature distribution.
  5. Qualitative Analysis: Researchers explore the meaning and context behind linguistic behaviors and language choices.
  6. Questionnaires and Surveys: Self-reported data from participants, including language preferences and attitudes toward languages, can be collected.
  7. Corpus Linguistics: Large collections of texts or spoken data are analyzed to uncover linguistic patterns.
  8. Experimental Studies: Researchers design experiments to manipulate variables related to peer interactions and sociolinguistic competence.
  9. Interviews: Semi-structured interviews provide insights into participants' experiences and perceptions.
  10. Audio and Video Recordings: Recordings capture spoken and nonverbal aspects of communication, such as gestures and facial expressions.
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I intend to use open-ended questions and target linguistics students, although I haven't yet begun to formulate the questions.
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I have AGL1 agrobacterium, it's not competent. i need to do it competent. any recommended protocols. i tried the TSS we use for E.coli but not working. also i tried the cacl2 protocol and don't get the +ve colonies in transfromation.
thanks
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Here is my Agro competent cell protocol
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Specifically, general education teachers' competence in identifying and assessing disability in an mainstream setting. Thank you so much.
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Hello mam you can search sample survey questionnaire which you can adopt and modify to fit in your study or you can search this
https://www.researchgate.net/publication/347258231_Questionnaire_on_Teachers'_Competence_in_Identifying_Pupils_with_Learning_Disabilities
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can you have a recent study about competency acquisition in home econmics
Practical skills
and Suggest activities to enhance competencies acquisition and Practical skills through utilization in home economics.
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"The value of a degree is in its RELIABILITY: when ill in a foreign country you can bet the MD has minimal competence. Like a driver's license.
HUMANITIES/SOCIAL SCIENCE degrees offer no reliability.
If you don't know what you get, degrees are worthless.
The market punishes BS"(Taleb 2018).
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You’ve actually posted THREE separate statements! Reliability is pretty much desired for any activity or process in life. Thus, the reliability of anything has a major impact on its perceived value.
Academic degrees and other Certifications are really just the equivalent of money in economics. They are tokens of the value of something else that may be traded for other values. As such, the particular “degree” is subject to the same qualifiers as monetary values in foreign exchange or domestic use. Reliability in use may or may not correlate to reliability in relative value. That is why exchange rates vary constantly, and internal issues like inflation impact the reliability of money’s value as well. Yet, for the most part, the “reliability” of money is solid as a medium of exchange.
So, not all degrees and certifications are necessarily equal in value in the marketplace of ideas or employment. Despite attempts to set up particular standards in different disciplines, the actual “certified” education or knowledge of someone in a particular field will vary depending on both the particular country a person was educated in, and often also the particular institution at which they studied.
Meeting minimum requirements can assure some level of confidence in the general public, but that also leaves a usually large range of abilities between those that have minimal competency and those who are truly experts. So, the actual competence of a “degreed” medical doctor at a clinic in a remote area may be quite a bit different from the competence expected from a medical doctor at a highly-respected hospital in a major city of a wealthy country.
The “value” of any certification also depends on the individual consumer. Many people are verfiably helped by the services of degreed and certified social workers of various types. Family and friend networks are great – maybe esential – but for some problems (maybe it IS the family!) the assistance and guidance of someone specifically trained and tested in aspect of social relationships cannot be duplicated.
The proliferation of “Diploma Mills” or other questionable certification services does make the “face value” of a degree more questionable. But the degree should just be the starting point of evaluation! If you stop there, any consequences are really your own fault. Verification of the schools legitimacy, the actual record of the person holding the degree, and any other work/social history of the person must be obtained and evaluated against your requirements.
In general, any person needs to provide some evidence that they are capable of meeting the requirements of an employer. Any employer must decide what evidence is acceptable. One of those pieces of evidence may be a degree or certification. It is NOT certain that such documents are particularly reliable unless backed up by reputable institutions.
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In this study I wanted to find out what factors that can be change milk yield of dairy farmers and do farmer’s attitudes, skills on farming, knowledge on farming relate with yield of milk production in cows. Further, living environment of the animals and nutrition of animals relate with milk production of cows.
The farmers’ attitudes can be affecting the way farmers treat their animals and it could be affecting the milk production. This study is focusing this context as we could be improving our milk production with the resource available with our farmers if their attitudes are contributing to milk production.
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Yes, In many ways, knowledge and skills affect dairy farm performance economically and health wise. Detecting mastitis early greatly reduces the cost of treatments and increase milk prodn. Knowledge on record keeping help economically.
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Can "literacy" refer to "competence" in EFL reseach?
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Literacy is a part of competence and is referred to correct usage of language esp. written. It is closer to performance because it presupposes language usage. Competence is more ideal, generalized knowledge or understanding how a certain languge works.
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The Metropolitan Autonomous University, Iztapalapa Unit, is seeking professionals with a doctorate degree 🎓 to compete for Full-Time Visiting Professor positions in the area of Chemical Engineering.
🔥 You will have the opportunity to compete for a permanent, full-time and open-ended position through a competitive examination 🏆. 🚀
Check out the convocation document! 👇👇👇👇
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hai Prof, I saw your note. I would appreciate if you could take my in as a faculty member or adjuct professor and I can do the work but FOR FREE. I dont need the money, but I just want to contribute knowledge to mankind for FREE via your univeristy. can you take me in without any pay ? thank you. its purely volunteer and CSR. you can put me in any faculty as you want
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Catano, V. M., Darr, W., & Campbell, C. A. (2007). Performance appraisal of behavior based
competencies: a reliable and valid procedure. Personnel Psychology, 60(1),
201-230
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See attached
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According to M. Fountopoulou, the 21st century teacher needs powerful tools and techniques for developing and cultivating personal skills, which are both exciting and significantly relevant:
- connecting theory with practice, - medium and long-term view of learning and teaching
- evaluation of the information
- the transformation of knowledge, the - - - the management of the school unit
- the combined application of scientific and pedagogical principles
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Hello Philippos,
When it comes to 21st-century education teacher's priority must rely on the transformative power of education, defined by UNESCO as the process that "involves teaching and learning geared to motivate and empower happy and healthy learners to take informed decisions and actions at the individual, community and global levels." (2023,
Combining scientific, pedagogical skills and values with a broader sense of the teacher's mission is essential to ensure learners develop skills better aligned with the challenges we face today.
Thus, teachers should be trained in the following areas to ensure they are prepared to foster learner's eagerness to learn and awareness about the world they live in:
- social-emotional skills
- critical thinking and problem-solving skills
- resilience and flexibility
- collaboration and empathy
- pedagogical use of technology
UNESCO. (2023). Five questions on transformative education. UNESCO. Retrieved 11-08-2023 from https://www.unesco.org/en/articles/five-questions-transformative-education#What%20Is%20%E2%80%9CTransformative%20Education%E2%80%9D?
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"The Peter Principle: Why Things Always Go Wrong" is a satirical book written by Dr. Laurence J. Peter and Raymond Hull, published in 1969. The book presents a humorous and thought-provoking perspective on organizational dynamics and the challenges that arise when individuals are promoted to positions of incompetence. The central thesis of the book is the Peter Principle itself, which suggests that people in a hierarchical organization tend to be promoted to their level of incompetence.
Here's a summary of the key ideas and concepts explored in the book:
  1. The Peter Principle: The authors propose that in a hierarchical organization, employees are promoted based on their performance in their current roles. However, as they continue to excel, they eventually reach a point where they are promoted to positions that require skills, competencies, or expertise different from what they have demonstrated. This results in individuals functioning at a level where they are no longer effective due to their incompetence in the new role.
  2. Incompetence and Promotion: The book humorously discusses how the process of promotion can lead to a cycle of incompetence. Individuals who perform well in their current roles are rewarded with promotions, which continue until they reach a position where they are no longer successful due to a lack of relevant skills or abilities.
  3. Humorous Examples: The authors use entertaining anecdotes and case studies to illustrate the Peter Principle in action. These examples demonstrate situations where employees with specific skills are promoted into roles where those skills are no longer relevant.
  4. Hierarchy and Bureaucracy: The book critiques hierarchical organizational structures and the bureaucratic nature of promotions. It highlights the tendency for promotions to be based on previous achievements rather than future potential.
  5. Impact on Organizations: The authors explore the consequences of the Peter Principle on organizational efficiency, effectiveness, and morale. They suggest that this phenomenon can lead to inefficiencies, mismanagement, and frustration among employees.
  6. Suggestions for Improvement: While the book is primarily satirical, it does offer some lighthearted suggestions for addressing the issues raised by the Peter Principle. These include promoting employees randomly, promoting only those who show incompetence in their current roles, or encouraging a culture of lateral movement instead of upward mobility.
  7. Satirical Tone: "The Peter Principle" uses a witty and satirical tone to highlight the absurdity of organizational practices. It pokes fun at the idea that people are promoted to positions for which they are ill-suited, creating situations that can lead to comical or frustrating outcomes.
  8. Reflection on Human Nature: The book invites readers to reflect on the nature of human competence, the challenges of organizational management, and the ways in which well-intentioned systems can sometimes lead to unintended consequences.
Overall, "The Peter Principle: Why Things Always Go Wrong" is a humorous exploration of organizational dynamics and human behavior within hierarchical structures. While it should be read with a sense of satire, it offers insights into the complexities of promotions, leadership, and competence within organizations.
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Very good summary ! Gaurav H Tandon Am in agreement with a humorous perception of the Peter Principle and related hierarchical incompentence paradoxes, but it is factually a dangerous behavioral phenomenon, especially when it arrives at the autocratic, dictatorial and totalitarian level.
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What is peter principle in management ?
The Peter principle states that a person who is competent at their job will earn a promotion to a position that requires different skills. If the promoted person lacks the skills required for the new role, they will be incompetent at the new level, and will not be promoted again. If the person is competent in the new role, they will be promoted again and will continue to be promoted until reaching a level at which they are incompetent. Being incompetent, the individual will not qualify for promotion again, and so will remain stuck at this final placement or Peter's plateau.
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From the perspective of human resources in education, politics, economics and technology, the hierarchy of incompetencies is the key, dear Gaurav H Tandon This implies that persons with the highest double character, double standards and lowest ethics always make it to the top of an organization, may it be a corporation or the state. Certain fields like entrepreneurship (innovation), independent scholarship and the arts are more exempt from this archaic paradox of human organized behavior that persists in modernity, due to unbroken evolutionary patterns. The flatter the degree of organization, the more competence counts. Centralization does always reinforce the Peter Principle and similar paradox hierarchies of organized human incompetence.
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Hello Science community,
I am working with several Agrobacterium strains (GV3101 pMP90, GV3101 pMP90 & EHA105). All of these strains are sensitive to the expected antibiotics when using only glycerol stocks of the strains for inoculation of solid and liquid media. However, after I made them chemically competent for transformation, the selection of the strains no longer works.
I have repeated the competenting with freshly made solutions to rule out contamination and changed the antibiotics used, but the problem remains the same.
Perhaps someone of you can give me an explanation?
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Try streaking and working from single colonies
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  • I have been preparing competent dh5alpha cells in the lab with good competency not excellent. however, have not been able to transform my CRISPR plasmid yet. I am following all the desired steps still unable to attain the correct colonies. plz, throw some light where I can be making mistakes. Plasmid is from addgene (pSpCas9(BB)-2A-Puro (PX459) V2.0)
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If your CRISPR vector is lentiviral based, I think it is better to use other strains of component cells instead of DH5a. It is easier to acquire undesired plasmids in this scenario.
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What is education for sustainable development competencies?
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Some thoughts on education in these contexts:
1. "Using a Spare-Time University for Disaster Risk Reduction Education", chapter 8 in https://www.routledge.com/Learning-and-Calamities-Practices-Interpretations-Patterns/Egner-Schorch-Voss/p/book/9780415334907
3. "Using a Spare Time University for Climate Change Education" https://doi.org/10.1007/978-3-642-10751-1_16
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Where i should add the following in the manuscript file?
(1) Competing Interests
(2) Author's contribution statement
(3) Ethical and informed consent for data used.
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Before the references section. You should add a section heading for each item without specifying a number for the title
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You need to make high level practically actionable proposal that will help RMG industry create a collaborative culture of ‘competing together rather than
competing with each other’ among the various supply chain stakeholders.
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And what is RMG industry?
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Essentially i am looking for material on the debate between the need for a PHD in higher education vs the competencies of other sorts of practitioners/educators/teachers.
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Some professors let you speacialize in medicine first after you have written a PhD. Writing a PhD gives you a logic way of thinking and a base to evidence test your findings.
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Who is the ideal learner? Is it the learner who works hard and memorizes everything he is responsible for in the exam and gets high grades, or the one who can't get high grades in the exam because he doesn't have the ability to memorize, but has creative, critical and analytical thinking competence?
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Academia is about archiving knowledge, learning is about creating new knowledge, i.e. learning is about creativeness, knowledge is about archiving.
It works like a division of labor; the ideal learner is a creator of new knowledge, but in science the archiving function remains the foundation of learning, dear Tolga Sarıca
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What makes parents want to control their grown-up children even when they are competent professionals
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They do not understand that their little baby is grown up now.
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I am in the process of conduction my dissertation research at Liberty University and would appreciate being able to utilize Professor "César Leal-Costa's" developed instrument for nursing communication competency. Does anyone know how I may contact him to procure written permission to be able to use it? I would greatly appreciate any assistance
Thank you
Pat
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Remember that validity and reliability are established for a particular sample/population at a particular point in time. You might still need to pilot the instrument and establish applicability to your study.
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Overtime, there have been many methods , approaches and strategies being used and adopted in the teaching and learning of English Language ranging from grammar method, audio-visual, communicative competence teaching , etc.
However, most of these approaches, strategies and methods are usually being referred to as being traditional or something, significantly at the advent of technological advancements and information-driven economy.
There have been many new methods, approaches and strategies infused with technology principles and practicals in the 21st century.
Kindly tell me the ones that you know or have applied before or have read about before.
Thank you for you for your time and help.
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I have applied Mobile-Assisted Language Learning (MALL): MALL leverages mobile devices and apps for language learning anytime and anywhere. Mobile technology provides access to language learning apps, online dictionaries, language exchange platforms, and multimedia resources. MALL harnesses the power of mobile technology to provide learners with accessible, personalized, interactive, and continuous language learning opportunities, making it an impactful method for language acquisition and skill development.
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What is the disparity between emotional intelligence and emotional competence?
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Emotional Intelligence
Daniel Goleman points out that emotional intelligence is the ability to motivate and persist in the face of frustrations, control impulses and delay gratification, regulate moods, prevent misfortunes from hindering the ability to think, develop empathy and abundance.
Emotional intelligence allow you to know your emotions and the emotions of others and improve your social relationship by properly managing your emotions. It is about choosing freedom and responsibility. Emotional intelligence serves not to fall into the hopelessness of suffering without purpose.
Everything will depend on what attitude you take toward emotions. There are two:
1. A reactive emotional system.- you feel like a victim and are unable to influence people and situations. You think your desires will be achieved when others change.
2. A proactive emotional system.- you feel like a protagonist capable of influencing people and situations. You live here and now (in the present). You collect positives things from the past and build a future.
Emotional competences
Emotional competences according to Rafael Bizquerra is the sum of knowledge and abilities that help us to carry out necessary and diverse activities with a certain level of quality and efficiency, in which the role of understanding, management, and regulation of our emotions and those of others play a key role.
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I am currently working with a study titled "Knowledge, Competency, Adoptability and Sustainability of Artificial Intelligence (AI) Technology Among Physician Entrepreneurs in GCC Countries". I am in dilemma that which SEM model AMOS/SmartPLS will suit for the study. The total responses received so far is 220 out of the population size of 400. The main objective is to find out knowledge , competency, adoptability and sustainability of Artificial intelligence among Physician entrepreneurs.
I will be much thankful to you, if you can extend your kind feedback on this.
Regards
Dr.Sharfras Navas
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With the latest SmartPLS release, you can run both PLS-SEM and CB-SEM (like Amos): https://www.smartpls.com/downloads
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For my Ph.D. project, I am looking for the attitudes and practices of EFL teachers and students towards peer review in enhancing strategic competence. The aims to investigate the attitudes and practices of EFL teachers and students towards peer review in enhancing strategic competence in selected secondary schools.
please dear share your idea to concerns,
Thank you very much.
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Peer review can be an effective tool for enhancing strategic competence in EFL students. It encourages students to reflect on their own work, gives them the opportunity to receive feedback from others, and helps them to communicate their ideas more effectively. Peer review can also help students to develop critical thinking skills and improve their ability to evaluate the work of others.
To successfully implement peer review in EFL classrooms, it is important to provide students with clear guidelines and criteria for evaluating each other's work, and to train them in effective feedback strategies. Teachers should also be actively involved in the peer review process, providing guidance and support to students as needed. Overall, the success of peer review as a tool for enhancing strategic competence will depend on the attitudes and practices of both teachers and students, and their willingness to engage in the process.
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Hello, Respected researchers. What theoretical framework could be appropriate for a teachers‘ perception study regarding the application of AI in the evaluation of teachers' competence?
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Several theoretical frameworks could be appropriate for studying teachers' perceptions, depending on the research question and the specific context of the study. Here are three possible options:
  1. Social Cognitive Theory: Social cognitive theory emphasizes the importance of cognitive and behavioral factors in shaping individual perceptions, attitudes, and behaviors. This theory could be used to study how teachers' past experiences, knowledge, and beliefs shape their perceptions of teaching and learning.
  2. Self-Determination Theory: Self-determination theory emphasizes the role of intrinsic motivation and psychological needs in driving behavior and performance. This theory could be used to study how teachers' perceptions of autonomy, competence, and relatedness influence their engagement and commitment to teaching.
  3. Ecological Systems Theory: Ecological systems theory emphasizes the interplay between individual, social, and environmental factors in shaping human development and behavior. This theory could be used to study how teachers' perceptions of their work environment, colleagues, and students influence their beliefs and practices.
These are just a few examples of theoretical frameworks that could be appropriate for studying teachers' perceptions. It's important to choose a framework that is aligned with the research question and context of the study, and to clearly articulate how the chosen framework will guide the research design and analysis.
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I have to perform the genomic integration of a gene, would it be better to use E.coli cells made competent by chemical method or by electroporation?
Thank you
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Hello,
electroporation is more efficient, however, you should be sure that the DNA with which you want to transform the host bacterium, does not contain salt, which can prevent the electric current from passing and thus prevent the electroporation process and transformation of the bacteria.
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Which type of pulmonary medicine competencies are included in undergraduate training of medical students in your medical school.
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Pulmonary medicine is the sub-specialty of internal medicine that focuses on the diagnosis and management of disorders of the respiratory system, including the lungs, upper airways, thoracic cavity, and chest wall.
Pulmonary rehabilitation plan may include the following training and education:
  • Breathing techniques, you may learn specific techniques such as pursed lip breathing, yoga breathing or breathing with computer-aided feedback.
  • Education
  • Psychological counseling
  • Exercise training
  • Nutritional counseling
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I am doing a paper study on movement competency and need resources to be cited and as resources too.
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doi: 10.3390/sports8040039.. 2020 Mar 26;8(4):39.Sports (Basel)
Movement Competency Training Delivery: At School or Online? A Pilot Study of High-School Athletes
Simon A Rogers 1 2, Peter Hassmén 1, Alexandra H Roberts 2 3, Alison Alcock 1, Wendy L Gilleard 1, John S Warmenhoven 2 4
Affiliations expand
  • PMID: 32224945
  • PMCID: PMC7240720
  • DOI: 10.3390/sports8040039
Free PMC article
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ACM and IEEE-CS Release Computing Curricula 2020, Global Guidelines for Baccalaureate Degrees in Computing. The Association for Computing Machinery and the IEEE Computer Society have issued Computing Curricula 2020 (CC2020): Paradigms for Global Computing Education. Developed by a 50-member task force drawn from 20 countries, CC2020 outlines international recommendations for baccalaureate degrees in computing.
CC2020 is designed to be comprehensive, delineating the latest curricula for computing disciplines including computer engineering, computer science, information systems, information technology, and software engineering. CC2020 builds upon a CC2005 report by including new disciplines such as cybersecurity and data science, as well as other significant “add-ons” to reflect the changing dynamics of computing, computing education research, and the workplace. These additions include:
  • Transitioning from knowledge-based learning to competency-based learning
  • Expanding curricular and competency diagrams and visualizations
  • Establishing an interactive website that will bring CC2020 results to public use
  • Charting a framework for future curricular activities
“A key theme of the CC2020 report is that students must have the requisite knowledge and skills but that their education must go beyond these important building blocks to foster competencies.”
source: ACM and IEEE-CS Release Computing Curricula 2020, Global Guidelines for Baccalaureate Degrees in Computing
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yes
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Which models/frameworks are people using for curriculum evaluation?
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We have published a summary proposal for competence measurement. Maybe helpful for your further planning.
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Do you think employees who THINK that they are more competent will be more engaged in their work, or less? Or this perception will not have any influence on their engagement?
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Yes, if it should not be quashed, but also their opinion of leaders' competence, and their belief of their leader's opinion of their competence.
And of course left alone it can lead to bad product or high costs and slowed personal development.
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Does anyone have access to a PDF version/link for Berlin questionnaire for competence assessment in EBM?
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  1. Hola, tal vez escribiéndole al autor te facilite la herramienta rkunz@uhbs.ch
  2. También te dejo otra herramienta validada para evaluar las competencias en profesionales de la salud en MBE
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I`m conducting a Ph.D. dissertation and looking forward to identifying the effectiveness of Web 3.0 in developing EFL teaching competencies.
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شكرا جزيلا د/إبراهيم
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I have a group of 16 students in my sample. 14 students evaluated themselves (anonymously) on 24 competencies prior to an intervention. Following the intervention, 12 students evaluated themselves (again, anonymously) on the same set of competencies. Because I can't compare each individual's pre and post score, I want to compare the means of each of the competency self-evaluation scores, pre and post. I can't figure out what to do.
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If it is interval/ratio level data with related samples, it should be a related samples t-test. If the DV is measured on an ordinal scale, I think it would be the Wilcoxon T-test. I can check my Bannon book or loan it to you if that would help.
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From various research, the aspect of competencies is viewed from the 4 Cs: communication. Cooperation, creativity and collaboration. The issue from my point of view is, do you consider entrepreneurship and innovative competencies as important factors for the 21st-century world of work and businesses? If these two competencies are important, what are their similarities and differences as compared to the 4 cs
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Innovation and entrepreneurship are two concepts that are often closely related and discussed in academic research. While they share some similarities, they also have distinct differences in terms of their competences. In terms of similarities, both innovation and entrepreneurship require a certain level of creativity and risk-taking, as well as a willingness to embrace change and uncertainty.
In terms of differences, innovation competence often focuses on the ability to generate new ideas, products, and processes, as well as the skills needed to implement them successfully. It involves the ability to identify new opportunities, research and analyze potential solutions, and develop and test new products and services. Innovation competence is therefore closely related to research and development, and often involves working in teams to bring new ideas to fruition.
On the other hand, entrepreneurial competence often focuses on the ability to start and grow a business venture, including developing and executing a business plan, securing funding, managing resources, and marketing and selling products and services. It involves identifying market opportunities, understanding customer needs, and building relationships with stakeholders. Entrepreneurial competence is therefore closely related to business management and strategy, and often involves working independently or leading a team to achieve business goals.
Despite their differences, innovation and entrepreneurship are often intertwined and both play a critical role in driving economic growth and creating new opportunities. Research into innovative and entrepreneurial competences often emphasizes the importance of education and training to develop these skills, as well as the need for supportive policies and institutions to foster a culture of innovation and entrepreneurship.
In summary, while innovation and entrepreneurship competences share some similarities such as creativity and risk-taking, they differ in their focus and implementation. Innovation competence emphasizes generating new ideas and products, while entrepreneurship competence emphasizes starting and growing a business venture. Both competences are important for driving economic growth, and education and supportive policies are key to developing these skills.
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SMEs need to build its resilience to survive in turbulent times. Identifying core competencies and factors that build resilience are challenging for SMEs. The question persists, what makes SMEs resilient in turbulent times?
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SME what does it mean here?
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There is a trouble for me that when I was purified the antibody the rat's Fc included using protein G, but I want to keep the activity of the antibody, so I want to using another antibody mouse' Fc included to compete with the rat's Fc antibody to get the free antibody with rat's Fc, does this idea available?
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Whether the competition would work depends on the the relative affinities of the two antibodies for protein G (which depends on the subclass) and the concentrations of each. Mouse IgG1 and IgG2a have the strongest binding to protein G among mouse subclasses. Rat IgG2a has the strongest binding among rat subclasses. You also will have to allow sufficient time for dissociation of the rat antibody from protein G, which may be slow due to high affinity binding.
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I work with a thermophilic enzyme, its optimal temperature is 50 C. From some assays at 50 C and at 35 C, I was able to construct two lineweaver burke plots.
I want to ask you if my interpretation and understanding sounds correct. Comparing the Km/Vmax from either set, it appears that 35 C is a better temperature for activity. However, this enzyme experiences strong product inhibition and the higher temperature must be beneficial in reducing inhibition.
So....higher temperature = more energy = less binding efficiency = greater Km at 50 C ?
Since the product competes for binding to the active site, by reducing binding efficiency the exchange rate of product/substrate is improved and overall production is improved?
How would you report/identify the kinetic values for this enzyme? The true Km / Vmax would be at 50 C? How accurately should one describe "optimal" conditions before considering the Km / Vmax values for an enzyme? Would temp, pH and salt conc. be the main three conditions or are there others?
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While Dr. Buxbaum's remarks are all pertinent, I do not think that a more detailed analysis of the data (more data points, nonlinear fitting etc) could change the fact that your enzyme is more active at 35°C than at 50°C.
This is in contrast with your initial statement that "[the enzyme's] optimal temperature is 50°C".
Perhaps you meant to say that the organism from which the enzyme is derived grows optimally at 50°C?
If this were the case, and barring any mistakes in data collection (e.g., using two stocks of enzymes with different specific activities), there may be several reasons why your enzyme in vitro performs better at 35C than at the 'physiological' temperature of 50C.
I cite a few examples:
1) As you noted, the initial rates upon which your analysis is based have been collected in the absence of product - and, for that matter, of any inhibitor potentially existing in vivo. Physiological inhibitors may be binding more tightly at 35°C than at 50°C, thus offsetting the inherently greater efficiency of the enzyme at the lower temperature.
2) Conversely, if your assay mixture contains an inhibitor (e.g., some ion) that binds more tightly at 50°C, this could explain the in vitro pattern
3) pH 8.5 is a bith high, and may not reflect the in vivo pH at which the enzyme operates. Based on how temperature affects the pH-dependence of activity, testing the enzyme at, say, pH 7.5 might show a higher activity at the higher temperature.
4) Your isolated enzyme may be less stable at 50°C than at 35°C, wheras in vivo some interactor may stabilize its structure/acivity.
And so forth...
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Respected colleague,
This question does not seek answers in the sense that both competence and loyalty are important.
For example: imagine you own a company and have two candidates for CEO. One is competent, but you know he / she is not loyal. You trust others, but you know that he / she is not competent.
If you had to decide between them, which one would you choose?
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It depends on the situation, when there is no critical mass of one or another, the troubles begin - be it in private sector, but it in public sector. Anyway, loyalty is much more necessary in the public sector than in the private, while competence is important everywhere.
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I am interested in reviewing research or hearing opinions based on the subject of adhering to the BACB Ethics Code when it comes to providing services solely within one's scope of competence while also acknowledging cultural responsibility. How can BCBAs provide ethical services to clients whose culture drastically differs from theirs? Is there ever a situation where a person's culture would present an issue outside of someone's scope of competence? If so, how would a BCBA reconcile these two issues?
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I mentioned the virtue for more help.
Your point that sometimes honest people are abused in some places, so honesty is not good, is not a clear reason.
The main principles of morality are accepted in the conscience of people, even if we do not accept them.
If we do not accept these principles, how can we follow them?
Honesty, justice, non-harm, trustworthiness are moral principles that everyone in the world understands, even if they cannot act on them.
Under the set of normative ethics, i.e. applied and professional ethics, medical ethics, environmental ethics, etc., specific and respectable principles and laws are defined in all fields, regardless of country, nationality, and race.