Science topics: Medicine
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Medicine - Science topic

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Questions related to Medicine
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If the ambient temperature is very cold, below -15 degree celcius it's difficult to handle medicine for veterinarians specially in field conditions.
What are the best way to prevent freezing of medicine (in a vial) in lower temperature?
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I think antifreeze...that will be compatible with the Medicinal agent should be used...maybe organic antifreeze... propylene glycol, glycerol maybe NaCl .... I'm not sure!
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With the appearance of COVID-19 vaccines on the market, many available choices are there.
Which one is good?
Which one is safest?
Which one is most expensive?
Which one is easiest to store?
How many doses are required?
Other than intramuscular injection, any other forms?
How to check immune response after?
Do we need post-injection blood test?
Do we need annual booster dose?
Do we need new vaccines every year by prediction as if flu vaccines?
Any contraindications?
Any allergy from vaccination?
Do we need to mask after injection?
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COVID-19 vaccines are unable to provide life long immunity against the disease.
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In the structure of many drugs, there is a carboxylic group
What is the significance of this group? Why should it exist in the structure of a drug?
Do you know any article or book or reference about this subject?
Thanks a lot
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In all metabolic processes in nature, electron transfer takes place at the molecular level. Two fundamental atoms in all living entities are oxygen (O) and nitrogen (N). In direct combination, they form NO, which is one of the most crucial biomolecules because it has a free electron ("free radical"). It is part of a universal communication system in biologicals cells.
If we go one level of abstraction higher, we find the amino (NH2) and the carboxyl (COOH) groups. In the carboxyl function, the electrons can migrate from one O to the other via the C atom (mesomerism). Thus, the H atom can easily migrate to the "partner" NH2 - the electrons are "free" and can participate in biological processes.
It is also why phenols, especially polyphenols (green tea EGCG, resveratrol, quercetin), are biologically very active. If both functional groups occur within one molecule, we have one of nature's most essential building blocks, amino acids.
With more atoms and larger molecules, the electron transfer becomes more complicated, but it can explain almost any drug's mechanism of action. It is perhaps interesting to note that electron transfer within biomolecules is sometimes completely different from what we know from the chemical laboratory.
That is why "free radicals" in the body are not generally harmful but vital.
SUMMARY
In summary, it is one of the most important functional groups in nature. That is the reason why it occurs as a functional group in so many drugs.
Attached you will find a link to a paper describing the effect of some functional groups in drugs.
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The general public must be made aware of the mode of transmission, presenting symptoms and the measures that can be undertaken to prevent the spread of infection.
Few options- Media, Webinars...
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Awareness can be increased if everyone is involved, the task of making people aware of COVID-19 prevention should not be left to the government alone. Let all stake holders be involved: that is civic leaders, the church, the education bodies, traditional leaders NGOs and the others.
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Bacteriophages very effective against infections.
Many of them such as anti-Staphylococcus or anti-Streptococcal widely used in practical medicine.
Some bacteriophages can be oncolytic and effective against cancers.
How Bacteriophages recognize and lyse cancer cells? Mechanism of action ?
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As I know, these mechanisms are poorly studied for today. But it is well-known that some bacterial species/strains have surface antigene similarity with many of the human and animal tumors. On this fact, one kind of the anticancer vaccines production is based. If you want to obtain a more detailed consultation and the recent references in this field, try to connect with Dr. Gennady Didenko or Dr. Irena Voyeykova in the R.E.Kavetsky institute of experimental pathology, oncology and radiobiology, NAS of Ukraine.
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There is a continuing accusation by alternative medicine practitioners that their method cannot be proven or their proof is inadequate. The basic principles, diagnostic, nomenclature and medical methods of Western and alternative (eastern) medicine are different. The western is linear and reductive, the eastern is more network-oriented. These require different methods of statistical analysis. Can they be judged by an approach?
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The scientific method can be successfully applied to natural pharmacy !
I do not see a methodological problem, but an economic one.
Profiteering-from-disease is the standard formula, for the moment, and this 'naturally' implies a bias for certain medical methods, e.g. surgery, drugs.
An 'ill' medical system produces also 'healthy' winners.
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RNA vaccines follow a different strategy, without using any "real" component of the virus at all. Instead, researchers aim to trick the human body into producing a specific virus component on its own. Since only this specific component is built, no complete virus can assemble itself. Nevertheless, the immune system learns to recognize the non-human components and trigger a defense reaction. So May I ask, What are your opinions about the safety and efficacy of the BNT162b2 mRNA Covid-19 Vaccine?
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I am looking for a board certified psychiatrist with specialty in sleep medicine and addiction medicine? Any referrals?
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For addiction part you could try Prof. Norbert Scheerbaum, Uniklinikum Essen, Psychiatry.
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Do you know any journals in the area of medicine/pediatrics/nutrition that publish protocols of systematic reviews? No APC or Low APC
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Journal of Nanomedicine is an open source , nno APC Journal in this field.
May be , there are other free Journals.
Thanks
N Das
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Shall the scientists take into their consideration the different side effects of the coronavirus and the medicine they are going to use against this virus? Or the have to focus only how to kill this disease 🦠 nowadays?
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Dr. Ahmad A. Al Rababah: The important thing is how the world is looking for this disaster. The vaccines, especially for Coronavirus Disease (COVID-19), are one of the "big business". They are looking for COVID-19 as a way for money production. Hence, the gap between rich and poor has increased dramatically.
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It is known that scientific knowledge is replicated each time at more unusual speeds, however, humanity expects more from our scientific work, that is, solutions to problems that have accumulated and that it is necessary to solve to improve the quality of life . It would be good to reflect on those expectations.
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Carona vacciene if it proved effective
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COVID-19 is mainly a respiratory disease that affects the lung, although other organ structures with endothelium seems to be affected too.
When should we do imaging?
What is the aim of the imaging?
How can it help with management?
Do you agree with the following consensus statement?
How will you adjust your own practice and difficulties encountered? Why?
Ref:
The Role of Chest Imaging in Patient Management during the COVID-19 Pandemic: A Multinational Consensus Statement from the Fleischner Society. Chest. 2020 Apr 07.
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Way too soon to answer that. Need some evidence base to emerge first
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What is the better option to improve immunity ? Medicine or diet ?
As per Ayurveda, Oja is the Bala (~immunity) which is originated by the Ahara which further nourishes Rasa, Rakta etc Dhatu and Finally it converted in Oja.
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Both of can be beneficial
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Deep Reinforcement Learning Training course
Time: January 15-January 18
DeepLearning Training course
Time: January 27-January 30
(Report for three days on the first day; Deploy the computer test in advance)
III. Lecture 1:
Course 1. Introduction to Intensive Learning
Course 2. Strengthen the foundation of learning
Course 3. Deeply strengthen the foundation of learning
Course 4, Multi-agent Deep Intensive Learning
Course 5. Multi-task deep intensive learning
Course 6. Strengthen learning and application
Course 7. Simulation Experiment
Course 8. Supplementary courses
IV. Lecture 2:
Lesson 1: Tensorflow Beginners to Proficiency:
Lesson 2: Image Classification:
Lesson 3: Object Detection:
Lesson 4: Face Recognition:
Lesson 5: Algorithm Implementation:
1. Convolutional neural network CNN
2. Circulating neural network RNN
3. Strengthen learning DRL
4. Antagonistic generation network GAN
5. Transfer learning TL
6. Specific examples of practical medicine, remote sensing images, oil exploration and intelligent transportation
Contact person: Li Luxin (teacher)
Mobile phone: 13311241619
QQ: 1942892948 (same as WeChat)
Strengthen learning QQ exchange group number: 872395038 (add group remarks: Li Luxin invited)
Deep learning-distance online course QQ group number: 1057802989 (plus group remarks: Li Luxin invited)
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This is an online course, which is taught in Chinese. Contact luxinli to ask for the registration form
Tel: +8617710606703
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Discussions could be in any area e.g. medicine, engineering, biomedical engineering, microbiology, etc.
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Качество образования зависит от индивидуальных особенностей учеников. Однако, самым главным является вербальное общение. Оно помогает развиваться ученику. Нехватка вербального общения приводит к понижению уровня развития сознания человека.
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I wish you all a Merry Christmas and a Happy New year!
Best wishes Henrik & Ruslana
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Merry Christmas.
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May the New Year bring you happiness, peace, and prosperity.
Wishing you a joyous 2021
What are your wishes for the new year 2021?
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^^ To: All 19 million scientists and researchers at RG platform!
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Dear Colleagues,
Do you know of any applications that help adjust references in a manuscript to a journal's stylesheet? I am familiar with Mendeley but I was wondering whether there is program that does not require prior uploading cited papers (just as Mendeley does).
Thanks a lot!
Monika
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dear definitely many others apps there,but i suggest according user friendly convenience
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Could we call published papers from all disciplines as SCIENTIFIC PAPER or just we say it for physics, biology, chemistry, mathematics, engineering, medicine or related things whereas linguistics or i.e. history is same?
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Sometimes, we have a paper that is relevant to many areas. For instance, green technology refers to any technology intended to reduce the impact of humans on the environment; it is related to solar, wind, and hydroelectric dams, to name a few.
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Vertigo is a condition that can make it feel like you or your surroundings are spinning, sometimes leading to a loss of balance, according to the U.S. National Library of Medicine.
Coronavirus 2019 or COVID-19 is a novel entity which had led to many challenges among physicians due to its rapidly evolving nature. Vertigo or dizziness has recently been described as a clinical manifestation of COVID-19.
So, Are dizziness and vertigo COVID-19 Symptoms? and why?
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Because covid_19 virus attack different organs and system after viremia the virus localised inCNS and cause both dizzeness and vertigo.
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This discussion section is about to Explore the issues that medical providers - doctors - nurses face during their battle, share your experience on covid unit,
In addition which factors facilitated in supporting you(mentaly and physically)?
How good does the developed protocols and plans of preparedness work on your facility?
Thank you for your time!
I am looking forward to your replies
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@Aldo P. Thank you. I think Health care workers around the world should be saluted and appreciated in many ways for the selfless acts of humanity we have all illustrated during these unspeakable times. Thank you for your service.
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I am a high school student writing a medical innovation project for a competition. My project involves TALENs gene knockdown and delivering it to the brain via the high-capacity adenoviral vector (HCAdV). The project will be in vivo (mouse models).
I need to write my procedure so I want to understand how TALENs can be packaged in the viral vector. From what I know, plasmids are transfected into cells and they produce the proteins that construct the components of the viral vector. I would greatly appreciate an explanation of how this process works, how TALENs can be packaged in the vector, and any other tips that you might have for my project.
Thanks
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As a researcher, you may be frustrated in finding continuous funding for sustaining your research. However, would there be any conflict of interest to be a researcher as well as a fund raiser simultaneously at the same time?
What regulations are there to limit the grey area?
Which authorities were looking on such issue?
What if the fund raising is for charity organizations in the field (particularly pediatrics and rare diseases) and is unrelated to the researcher's work?
In medicine field, the practice of physicians fundraising from their own patients raises three main concerns:
(1) undue pressure on patients to contribute,
(2) possible expectations of preferential treatment from donors, and
(3) concerns about patient confidentiality and trust.
What do you think?
https://doi.org/10.13140/RG.2.2.26948.24966
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This largely depends on the system of financing science in a given country and the policy of financing research in specific types of universities. It is not a comfortable solution for researchers and scientists to independently search for sources of funding for their research. Systems of granting grants and subsidies for specific research projects should be developed and improved, taking into account the potential effects of the results of these studies on solving specific problems of the development of civilization.
Best wishes,
Dariusz Prokopowicz
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In the past 15 years or so, there has been exponential growth of technology in surgery. This new era requires a specialized workforce. The 20th century was truly the age of surgeons; however, the 21st century will be the age of multidisciplinary patient care. One good example is the treatment of cancer patients
Are General Surgery trained personnel perform better in other specialties too?
How are their performance on other surgical specialties?
Any evidence to suggest their skill transferability to other disciplines?
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Dear Dr Sunny Chu Lik Au:
Thank for raising this important question. There is a dilemma of general or subspecialty. Subspecialty is important in developing the management of cases but in the same time it created a pinhole vision of the physicians and no one is looking to the patient as one unit and look to the overall need. Each subspecialty want to put the optimum for his work regardless of the overall need of the patient or his stage need.
I support my colleagues in the importance of training in general surgery for every other surgical specialty. I suggest 1 year as minimum time spend in general surgery if not making degree in general surgery as requirement for doing subspecialty study.
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A recently published article Medications for Anxiety: A Drug utilization study in Psychiatry outpatients from a Tertiary Care Centre Of Eastern India. SIDDHARTHA GHOSH, Swati Bhattacharyya, Amit Bhattacharya in Journal of Drug Delivery and Therapeutics is almost the copy of the article published in Nepal journal of Epidemiology. Authors forgot to change the place of their hospital in India instead of our hospital in Nepal Still. Manuscript Published. What to do with this type of Methodological rigor?.
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Dear RG colleagues,
For any similar case, I think that we should do the followings directly:
  • Write an email to the journal editor to inform about this case of misconduct or as so-called plagiarism. This journal must retract the article
  • Write to the institution of the authors informing them about this stealing.
  • Report it in the following portal: https://explore.researchgate.net/dosearchsite.action
In my personal opinion, the aforementioned steps are more than enough. No need for the court.
By the way, I have a related case:
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A patient with desminopathy (mutation Thr341Pro DES in a heterozygous state) with the progression of the disease has a decrease in taste and smell, immunosuppression, and an increase in IgA in the blood.
Oddly enough, but all this is characteristic of infections, including viral ones. For example, it is known that if the hepatitis C virus is not treated, then death will occur in 20 years.
In the identified case of late onset desminopathy, muscle weakness manifests itself at the age of 30, and death occurs 20 years after the onset of the disease.
Could the desmin mutation in myofibrillar myopathy be caused by an infection?
Perhaps the infection contributes to the progression of desminopathy?
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Dear Massimo Zipoli, thank you very much for your reply! As you know, desmin is expressed in all types of muscle cells (skeletal, smooth, cardiac muscles, diaphragm), as well as in tumor cells.
In this family with desminopathy, we identified a large number of cancers (n = 6): bladder (2 cases in men), prostate, skin, uterus, rectum (article in the appendix). For example, it is known that dysfunction and pathological changes in the smooth muscles of the bladder are associated with the overexpression of desmin.
Thus, the likelihood of infecting cells with the mutation is quite high.
Article
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Is it possible to use a medical computed tomography (CT) machine for the inspection of 3D printed parts?
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I am trying to make a nano-emulsion to convert a cancer medicine into its more bioavailable form following guidance from this patent
But I made some changes because I can only use food grade off the shelf surfactants(Tween 80 and Sunflower Lecithin). I found another paper using these surfactants and I successfully created a emulsion with 4:3:1 ratio of olive oil:Tween 80:Lecithin.
Unfortunately I don't have a sonicator and the emulsion I end up with is like milk and opaque. I use ultrasonic bath which helped but did not turn the emulsion translucent. When I dilute the emulsion in water(1:100 by volume) the water is still milky and not translucent. But the emulsion is stable, the drug does not precipitate, does not settle and the oil does not separate.
So I believe I am really missing the sonicator here to convert the particle size to <100nm. Any other way you know of creating nano emulsion at home or on the cheap ?
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Buy a piezoelectric disc and design one yourself.
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EBM suggests that doctors should avoid prescribing treatments that do not have sufficient or strong evidence in their favor. Decisions made backed only by expert opinions and supported by plausible pathophysiological explanations, although not yet sufficiently proven by high-level clinical studies, are not recommended by EBM in ordinary situations. However, in a serious epidemiological emergency, there is no time for such studies to be available. Under such circumstances, could not (or even should not) doctors agree to provide recommendations to their patients guided by studies or opinions based on unsatisfactory or weak evidence?
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Safety and evidence based medicine, public health and practice are desirable at all times. In emergency situations like the case of COVID-19, it would be justifiable to practice life saving measures with some liberty but still with best evidence available and no harm is clear before hand. It is a difficult choice between urgent need to safe life and lack of evidence of effectiveness.
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Hi there,
I am eager to hear from researchers or clinicians who have used n-of-1 studies for the above purposes. They seem to offer advantages over many other study designs, particularly for when there is little guidance or predictors of outcome on which therapeutic option to choose for a patient. They also seem rare, and most of the literature I've seen so far suggests that they have mostly been used for trying out different medicines.
I'm hoping to hear some encouraging stories of their use, but can see that there may be limitations with implementing them (due to costs / time etc.)
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Depends what you want to do with the data. However, there are some great "how-to" texts that you might want to look at (e.g.):
Nikles J, Mitchell G, editors. The essential guide to N-of-1 trials in health. New York, NY, USA:: Springer, 2015.
Janosky JE, Leininger SL, Hoerger MP, Libkuman TM. Single-subject designs in biomedicine. Springer, 2009
There are others that go back further but check them out
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Ayurveda, TM of India, advises to avoid Curd intake in diseases that have Kapha dosha predominance like Diabetes, Respiratory problems; in diseases arising out of Raktha dusti (Blood tissue vitiation) like Skin diseases and also in conditions where the digestive fire (Agni) is weak like during Night time. Regarding this Curd advisory, Ayurveda has very clear fundamental concepts and the findings of which have also been noticed in clinical practice as well.
Here I want to know are there any other Traditional system of medicine which has similar or any other observation about Curd intake?
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yes Hikmat or hakeems ( Eastern medicine ) as called in Indian subcontinent has number of dietary restriction in number of illness
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Dear Colleagues,
My team is planning to conduct a modified version of a scientific survey that was published by a different group a few years ago. We are going to significantly modify the survey and use it to investigate a different clinical population. We will, however, keep some of the questions used in the original survey. How should we best approach this without risking plagiarism?
We will say in future publications that will follow our survey that it is a modified version of a different survey. Which of the options below should we also pursuit:
(1) mention that our survey is a modified version of another survey already in the survey itself,
(2) paraphrase the questions that we will borrow from the original survey?
I will greatly appreciate your suggestions.
Thank you,
Monika Polczynska
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Request the pertinent permission from its Author or Authors and then make it reliable, validate it, etc. Pisometrically in its new modification and with its own "ad hoc" Normative Groups.
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Does anyone have soft copy of book "Epidemiology of Medicine" by Henneken. Please share.
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The link is no longer working. Dont have it too. Share if you find it
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integrity is often defined as being honest and having strong moral and ethical principles.
The world certainly needs it very much. Can we teach this quality to our students? should the parents be the ones that teach ethics to their children? Can society or, religious institutions teach this?.
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I agree with@ Irfan Adin Majid. It is a great responsability of a teacher.
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I had a few students help me with a simple but time-consuming task. The data they helped with will be used in a scientific paper. The students are part of the Student Research Program (SRP) at my institution and they received a class credit for their work with me. Should I include these students as co-authors on the manuscript?
I also had a student volunteer help me on the same research project. The student did not get a class credit for their help. Should the student be a co-author on the paper?
Thank you in advance for your opinions/suggestions.
Monika Polczynska
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Monika Połczyńska the best practice in my opinion would be discuss this issue (contribution/benefit) before one embarks on a research project.
In case of students' involvement in faculty initiated research, it is usually the university that formulates policies that best serves interest of all engaged in the project. However, it is good to have a signed student research agreement in place to clarify the benefits one would obtain from the research engagement (class credit, course grades, authorship, etc.).
In terms of objectivity towards authorship rights I agree with Abdulhameed Mahmood on the ICMJE guidelines, additionally you could also refer to the COPE (Committee on Publication Ethics) guidelines;
and
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comparative study to treatment ringworm in cattle between( chemical treatment and plant extraction treatment).
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Urtica masaica powder
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When it comes to Ambivalence, it can be a symptom of mental illness but it is also something we experience in our everyday life ( I certainly do, and my wife hates it) . Where would you draw the line between normal ambivalence and pathological ambivalence? Also what is the role of attitudes (if any) towards the object? I wrote an article about attitudes a while ago. The article can be found here:
The word is free..
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Dear Sir, Henrik G.S. Arvidsson Before anyone reaches a point where He/She has absurd thoughts of killing their spouses is the time when He/She should draw a line between normal or pathological ambivalence.
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Hello dear researchers
I have an opportunity to have a series of interview with great Iranian scientists from all over the world on my social media account.
I am listing the possible questions that I can ask!
If you were me, what were the questions that you wanted to ask!?
Please help me with your nice ideas!
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There are no G-d scientists, although G-d is the greatest scientist. As earthlings, with respect to your question, the development of our genius, e.g. the full healing potential of physicians and the medical profession, is bound to step over certain rules of one or more disciplines. It is my informed guess, that the new global economic growth engine of the 21st century will be human health, in holistic terms. We will gain a more sacred or higher understanding of the humany body and our biological condition on this planet, also in terms of practical ethics and health. Concerning the medical sciences, profiteering-from-disease is no future model. Wishing you good luck with all your interviews and much progress in your field !!!
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University graduates work in various companies and at first, find it difficult since what they learned is of very little or no help in the new job. The work is very specific and very little of it is covered in the university curriculum. should universities focus more on job-specific skills or continue with academic education? what are the consequences?
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I agree with Natalie Ann Gordon , in universities we teach with competencies at various levels and we think about the citizenship that society requires. Training focused solely on practice, leads in some cases to reduce the potential for critical thinking, the principles of the profession must be reinforced, and they can continue to develop their competencies throughout life.
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Global spotlight is on 2020 Nobel prizes which is slated to commence today, Monday October 5, 2020. Many researchers have been mentioned and nominated in various capacities for their discoveries such as;
1. American Mary-Claire King, who discovered the BRCA1 gene responsible for a hereditary form of breast cancer.
2. The duo of Emmanuelle Charpentier of France and Jennifer Doudna of the US, for their gene-editing technique, the CRISPR-Cas9 DNA snipping tool, a type of genetic “scissors” in cutting mutated gene, and for insertion of a corrected manipulated one.
3. Dennis Slamon, American oncologist for research on breast cancer and the drug treatment Herceptin.
4. Leroy Hood, US gene sequencing pioneer.
5. And host of others.
Not only limited to medicine, in any field, who do you have in mind for his/her discovery roles in the past few years?
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Nobel Prize Winners in Chemistry:
1.) Emmanuelle Charpentier, Ph.D., Max Planck Unit for the Science of Pathogens (Germany) and,
2.) Jennifer A. Doudna, Ph.D., University of California, Berkeley.
They were awarded by the Royal Swedish Academy of Sciences for awesome impact in medicine after the development of a method for genome editing, CRISPR-Cas9, a highly robust, super-selective and precise gene-editing tool where chemistry is believed to play great roles.
This discovery idea originally came from the knowledge of natural defense mechanism which bacteria use against viruses.
Today, it is really offering untold applications in treating and curing a number of genetic diseases and in the fight against cancer.
With its huge extensive role also cut beyond medicine and chemistry, its impacts also offer great benefits in agricultural and other areas.
From me, I can say, just like I earlier predicted that these people would win Nobel prize, the future for this technique is indeed limitless and shall offer more. Indeed, it's highly promising.
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the gut related diseases like White feaces, white muscle, white gut are doing much damage to shrimp by retarding growth and increasing FCR and eventually heavy losses. is there any medicine or cure available now apart from preventive measures?
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As COVID-19 cases continue to rise worldwide, experts are faced with a critical question: can a person catch the disease a second time? The answer to this question influences, among other things, the prospects of the vaccine and its ability to protect us from the disease.
In late August and earlier this month, news reports of COVID-19 reinfections surfaced from different parts of India – Bengaluru, Mumbai and Hyderabad.
On September 15, 2020, researchers from the Government Institute of Medical Sciences, Greater Noida, and the Institute of Genomics and Integrative Biology (IGIB), New Delhi, uploaded a preprint paper confirming two cases of reinfection from India. The patients – a 25-year-old male and a 28-year-old female, both healthcare workers in the Noida hospital – got infected with a different variant of the virus the second time, about three and a half months after their first infection. The next day, the IGIB team also confirmed reinfection in four Mumbai healthcare workers, although the report is yet to appear online.
The healthcare workers from Noida had more viral particles than when they got infected the first time, although they remained asymptomatic. The researchers also noted that the viral strain they were reinfected with contained a mutation that wasn’t present earlier, and which allowed the virus to resist neutralising antibodies – the kind of antibodies that prevent the virus’s entry into the body.
This is probably the first report of asymptomatic infection and reinfection, and it calls for better surveillance.
“As a significantly large number of people who are infected are asymptomatic, without surveillance, we would never be able to estimate the real numbers of infection. Therefore, surveillance of healthcare workers, who are at higher risk than the population, would be something really worth considering,” Vinod Scaria, a senior scientist of genome informatics at IGIB and one of the authors of the study, told The Wire Science.
Upasana Ray, a senior scientist of infectious diseases and immunology at the Indian Institute of Chemical Biology, Kolkata, agreed that long-term patient monitoring is important irrespective of the symptoms. She added that more gene-sequencing data should help us identify and understand the type of virus in circulation, and understand when a new ‘variant’ shows up.
Sequencing the virus’s genome also helps distinguish between reinfection, where the virus enters the body a second time and infects the person, and reactivation, where the virus remains in an inactive state in the body and later becomes active again.
Epidemiologists had speculated on the possibility of reactivation and reinfection of the virus even in April, when about 51 patients in South Korea who had been ‘cured’ of the disease tested positive again. South Korea’s Centers for Disease Control and Prevention initially proposed that they were cases of reactivation of the virus. But upon further research, they announced that the test results were all false positives: the test kit had detected remnants of the virus that were not infectious.
Other researchers reported the first formal case of reinfection on August 24, 2020, when a 33-year-old man from Hong Kong tested positive for the SARS-CoV-2 virus about four and a half months after the first infection. The reinfection, however, was less severe and the patient was asymptomatic.
One way to confirm reinfection is to test whether viral strains from the two infections are different. This is useful because as the virus mutates, different strains of the virus circulate in different regions at different times. In the Hong Kong case, scientists confirmed that the viral strain involved in the reinfection was different from the first infection. In fact, the reinfection strain was most closely related to a strain circulating in Europe around July-August, where the patient had travelled at the time. The study was published on August 25 in the journal Clinical Infectious Diseases.
Another case of reinfection has been reported from Nevada, in the US, where – unlike the Hong Kong case – the symptoms were worse when a 25-year-old man contracted the virus a second time. The authors of the preprint paper confirmed this to be a case of reinfection as five nucleotides present at specific places of the viral RNA from the first infection were different in the viral RNA from the second infection.
That said, the authors also considered another possibility: that the virus from the first infection evolved into a different type inside the body. If that were true, this would be the fastest rate of the virus evolving inside a person – nearly four times as fast as is known now.
Mind the rarity
Scientists have also confirmed instances of reinfection in Europe and South America. As of today, ten cases of reinfection have been confirmed from around the world.
These cases raise many questions. For example, are reinfections frequent or rare? Do subsequent infections evoke milder symptoms or worse? Can those who have been infected the second time spread the virus while remaining asymptomatic? And how do reinfections change the prospects of a vaccine?
A syringe with a vaccine is seen ahead of trials by volunteers testing for COVID-19, and taking part in clinical trials for potential vaccines at a research centre in Johannesburg,
In a press conference held on September 15, Balaram Bhargava, director-general of the Indian Council of Medical Research, said that although COVID-19 reinfections are possible, they are “very, very rare”, and added that it’s not a matter of serious concern.
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The coronavirus pandemic has brought the world to a grinding halt and no doubt has altered the lives of each one of us. I think COVID-19 also has an impact on our normal research (i.e. related to our relevant field) and diverted us to work on various aspects of coronavirus to help combat the virus.
What's your opinion in this regard?
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This pandemic has led researchers and research centers to shift the attention of researchers and research centers towards searching for a drug or vaccine against the emerging coronavirus, which has led to neglecting other axes such as cancer, diabetes, and other research fields..Even publication in journals has become more slowly due to the interest of journals in research related to COVID-19
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A study by Peeters et al. (2017) suggests that sugar traps cancer in a 'vicious cycle' which make it more aggressive and harder to treat (1). On the question-and-answer site Quora, Ray Schilling, MD, concludes: "there is a connection between the consumption of sugar and starchy foods and various cancers in man. Animal experiments are useful in suggesting these connections, but many clinical trials including the Women’s Health Initiative have shown that these findings are also true in humans. It is insulin resistance due to sugar and starch overconsumption that is causing cancer" (2).
References
1. Peeters K, Van Leemputte F, Fischer B, Bonini BM, Quezada H, Tsytlonok M, Haesen D, Vanthienen W, Bernardes N, Gonzalez-Blas CB, Janssens V, Tompa P, Versées W, Thevelein JM. Fructose-1,6-bisphosphate couples glycolytic flux to activation of Ras. Nat Commun 2017; 8: 922. doi: 10.1038/s41467-017-01019-z. https://www.nature.com/articles/s41467-017-01019-z.pdf
2. Schilling R. Why isn't sugar portrayed as bad like cigarettes? https://www.quora.com/Why-isnt-sugar-portrayed-as-bad-like-cigarettes
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The fact that cancer cells use more sugar than non-cancer cells, known as the Warburg effect, appears to form the basis of the current question. Nevertheless, it is not yet known if this effect is merely a symptom of cancer or whether it is the cause of cells becoming cancerous. Evidence indicating the way cancer cells metabolize sugar is not conclusive, either. Considering refined or added sugar, the bulk of the available evidence indicates that sugar is not a carcinogen. There is no evidence that eating sugar causes cancer or speeds up its growth. There is also no evidence that eliminating dietary sugar causes cancer to shrink or disappear. However, it is known that eating excess sugar, especially added sugars, can contribute to many chronic diseases such as obesity and diabetes, which are potential risk factors for several types of cancer.
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Have you ever imagined how the physically disabled people feel under COVID-19?
Which type of disability is most impacting these minority under COVID-19?
Autism? Cleft patients? Mental health patients? Deaf? Dumb? Blind? Loss of limbs?
How can we help them?
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President Donald Trump test positive for Covid-19
This is one of the shocking news listened ever towards blind people!!
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It's 99 days since the first case of COVID-19 in Hong Kong, and we are welcoming the 5th days of 0 new cases of COVID-19 following a week of <10 cases per day.
How should we define the end of a local endemic?
How long should the latent period be defined?
When is it safe to resume social activities?
Should territory wide screening of asymptomatic people be done before declaring the end of endemic?
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President Donald Trump test positive for Covid-19
This is definitely not the end of the COVID-19 endemic
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When will South America (or specifically Argentina) win a science Nobel Prize?
Another year without a Nobel Prize coming to South America
The last time that a South American scientist was awarded with a Nobel Prize was César Milstein, Physiology or Medicine, 1984. Are the richest countries rich because they inverts a lot in science? or they inverts a lot in science because they are rich?
The list is very short: Argentine 3, Brazil 1, Venezuela 1
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as we can see from the history of wars the technological advantage was usually the main factor in order to win the war. It means that investment in science at that time really can make some countries rich.
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How do you think artificial intelligence can affect medicine in real world. There are many science-fiction dreams in this regard!
but how about real-life in the next 2-3 decades!?
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AI has to transmit/mimic compassion somehow. COVID 19 patients fear loneliness and the scarce contact with the medical staff more than the consequences of the disease.
AI without empathic designs can bring lots of new problems.
The topic of cobots and humane treatments will demand a lot from medical applications of AI.
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The literature regarding gender and the distribution of personality traits ( Big five personality traits model as a reference,; McCrae & Costa) are pretty clear. Women score higher on traits such as agreeableness and openness for example. There are some examples in the literature regarding why there is a difference between men and women in terms of personality traits. However how does sociological factors such as the influence asserted by the individuals belonging to social group, ethnic group, culture etc. Can we say that women across the spectrum are more agreeable or open and men are less agreeable according the the big five personality traits model (McCrae & Costa 1985 etc) or are there other markers that also influence out traits...can it be that in some cultures women are less agreeable than men for example or do you think the big five model and the distribution of traits in terms of a gender perspective is universal? Are there any identifiable research gaps in your view? Best wishes Henrik
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Personality variations between men and women have a more heritability and socio-cultural basis than gender in particular. Cultural changes are very long-term, therefore the dynamics of personality variations are unhurried and steady.
Among four recent twin studies, the mean percentage for heritability was calculated for each personality and it was concluded that heritability influenced the five factors broadly. The self-report measures were as follows: openness to experience was estimated to have a 57% genetic influence, extra-version 54%, conscientiousness 49%, neuroticism 48%, and agreeableness 42%.
Refer to the study below:
Bouchard TJ, McGue M (January 2003). "Genetic and environmental influences on human psychological differences". Journal of Neurobiology. 54 (1): 4–45. doi:10.1002/neu.10160.
Also, differences in the magnitude of sex differences between more or less developed world regions were due to differences between men, not women, in these respective regions. That is, men in highly developed world regions were less neurotic, extra-vert, conscientious and agreeable compared to men in less developed world regions. Women, on the other hand tended not to differ in personality traits across regions.
Refer to the study below:
Schmitt DP, Realo A, Voracek M, Allik J (January 2008). "Why can't a man be more like a woman? Sex differences in Big Five personality traits across 55 cultures". Journal of Personality and Social Psychology. 94 (1): 168–182. doi:10.1037/0022-3514.94.1.168.
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The homoeopathic medicine consist minerals in it and the same nutrients are essential for the growth and development of the plant. So I asked myself whether the homoeopathic medicine useful for plant nutrition.
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Hello Dr. Sagar S. More,
There is a book entitled "Homeopathy for Plants: A Practical Guide for Indoor, Balcony, and Garden Plants" which might be of help to you. Homeopathic medicines for the wholesome growth and development of plants may at best serve as supplements but never as substitutes. And usually the concentration of minerals present in over the counter homeopathic medicines may not simply be sufficient to cater to the needs of a braod category of plants since the menerals and metalloids used are mainly aimed at human.
Homeopathy has been applied to horticulture for a long time but its use as a viabll alternative to plant medicines and supplements should not be wholeheartedly relied upon in my view. Apart from foliar application there is always the risk of the medicne being lost in a natural matrix such as soil, based on the latter's CEC.
It can be done, has been done, and we still have specific plant medicines hence the approach does appear to have its cons.
With regards,
Dr. Abhishek Mukherjee
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A patient with hereditary desminopathy (mutation Thr341Pro DES in a heterozygous state) with disease progression has a significant decrease in taste. How can this fact be explained?
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Probably affect facial nerve and glossopharyngeal nerve in the pons and medulla oblongata?
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I am looking forward to designing a Printed Electronics circuit for Pill Reminder/ Medicine Reminder. The circuit is printed on the back of the medicine stip.
I found some interesting circuit which based on IoT, Arduino to get a reminder at a particular set of time. IT cannot possible to fix the smallest microcontroller kit (i.e. ATTO) into medicine stip. I want to make a basic circuit with passive electronics components. Another idea is to design a circuit for a wire-break alarm or reminder with sufficient delay. The IC 555 dose-not possess longer delay and multiple wire-break alarm system.
If you have any ideas please share.
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If this is been developed it may be grateful for Alzheimer's patients
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Does an oral & Maxillofacial Medicine specialist or physician have experience prescribing buspirone to a patient with SSRIs-related bruxism?
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You can have a look at this article. Maybe it would be helpful.
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It seem individual's attitude to environment are changing rather than last year due to corona virus issues and challenges. What do you think?
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My view is that by mid-2021 there will be positive changes in environmental behavior and a reduction in destructive processes. Political conditions such as the US election and the trade war with China can also make a difference.
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What are different coil shapes used in Transcranial Magnetic Stimulation? What are their differences (in induced current)? Do they have different applications?
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Hi,
Actually, the influence of inductance value in a coil on TMS is eddy current strength. In addition, the coil design in physical configuration can affect the TMS distribution or depth. The TMS coil with eight shapes is commonly used in clinical application due to better high resolution than the round coil.
You can refer to the article below. Good luck!
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In your personal experience,How do you manage your life and make a balance between work, family and other related sections!?:)
I would be thrilled to have your points!
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Equally, dear Dr. Hossein
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Applications of bioinformatics in medicine is a key factor in technological advancement in the field of modern medical technologies.
In which areas of medical technology are the technological achievements of bioinformatics used?
What are the applications of bioinformatics in medicine?
Please reply
I invite you to the discussion
Thank you very much
Best wishes
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In precision med... Precision medicine is rapidly emerging as a strategy to tailor medical treatment to a small group or even individual patients based on their genetics, environment and lifestyle. Precision medicine relies heavily on developments in systems biology and omics disciplines, including metabolomics. Combination of metabolomics with sophisticated bioinformatics analysis and mathematical modeling has an extreme power to provide a metabolic snapshot of the patient over the course of disease and treatment or classifying patients into subpopulations and subgroups requiring individual medical treatment.... Azad, R. K., & Shulaev, V. (2019). Metabolomics technology and bioinformatics for precision medicine. Briefings in bioinformatics, 20(6), 1957-1971.
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It is reported by NBC that "Up to July 9, just over 200,000 cases of COVID-19 had been diagnosed in kids and young people in the U.S. in total. But from July 9 through Aug. 6, an additional 179,990 pediatric cases were reported — an increase of 90 percent in just four weeks. What changed? is covid-19 changing or our early understanding of it was wrong?
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Mahmoud Moghavvemi Worrisome matter!
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Hii expert,
I am a first-year PG student enrolled in Public Health (Community Medicine). I am looking for a list of Scopus/ISI indexed journals with no processing fee. In the area of medical education/public health/community medicine/health science. Please help me. Thank you in advance.
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Medical Education :
Medical Teacher
Medical Science Educator
Academic Medicine
Community Medicine:
Perspectives in Public Health
Scandinavian Journal of Public Health
Epidemiologic Reviews
This is not an exhaustive list. Hope it helps.
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I would like to learn the limitations of statistics in different domains of biological research. How it affects the outcome, future perspectives of medicine in terms of diagnosis, treatment, and effect of causative agents.
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"Does it make sense? will often cut a statistic down to size" - D Huff
Statistics is a 'play with numbers' in the sense that significance of a particular data can be 'shown' to exist (“There are three kinds of lies: lies, damned lies, and statistics.”- Benjamin Disraeli).
The statistical analysis would only grossly show an overall picture and may not fit in with every individual case (“Statistics largely deals with averages and these averages may be made up of individual items radically different from each other.” —Wilford I. King).
More than statistics, the study design, methodology have to be acceptable to standards and then statistics would help the data to a better understanding.
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What is your take?
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In my opinion the foundation of personality is inherited, self desires set the direction and environment cause transformation, as seed inherits the type of the plant in it self, a chance to go into the soil is similar to self-desires, while water, sunlight, air and fertilizers are environments. They all have a role to play in the process of a seed becoming a tree.
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There are two theories that are quite similar in nature, but different in substance, The theory of Mind and the theory of Mentaliz(S)ation, sorry, Im allergic to American spelling...pls dont kill me now :-) My understanding of them is this "Both of these concepts, mentalization and the theory of mind, describes processes that are metacognitive in their nature . Mentalization mainly concerns the reflection of affective or emotional mental states. In contrast however the, theory of mind focuses on things epistemic in nature such as beliefs, intentions and persuasions. My idea is that these two theories by them self are incomplete but combining elements of both, gives us a clearer understanding. Cognition and affect can't in my view be separated, they are both part of us as human beings and also a part of other animals. What are your thoughts? Am I wrong or right? I can stand criticism so bring it on...
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Dear Henrik G.S. Arvidsson I dont agree with you that mentalization and the theory of mind are incomplete, I would rather say they are vague and trying to beat about the bush. However, I agree with you that both facets; physical and non-physical go side by side as the two sides of the river, they are two different identities, yet essential and part of the same one entity the river. I think to understand mind we have to answer following questions:-
1. What are numerous non-physical entities, dimensions, constructs & elements.
2. What is the hierarchical / Interrelationship model.
3. How does theses non-physical entities function individually.
4. How does Multiple simultaneous occurrences and their effects occur.
5 What is the trans-formative phenomenon of mind and how it occurs.
6. What can be a perceived Mind Model.
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I often hear from friends negative things about academia, its boring, not connected to reality etc. I have been on and off in academia for 25 years but for the most part I have been in the real world, running businesses and working as a business consultant. I can still feel that in academia there is at least in my field a theoretical knowledge but still people doesn't understand how the real world operates. After university I felt like I knew everything, I knew Kotler backwards and forwards and all the theories..it felt like any way but when I started my first business (during my university years) I felt like I had to relearn everything. This lack of connection to reality was a problem for me and it is something I hear a lot for other business people. "Academics know nothing! ",one friend said and he has a Phd! Perhaps this illustrates the problem?
I guess it is the same in many fields..academia is seen as dry and not connected to the real world. What can be done about this or can anything be done? How do you view your education in relation to your working life? Do you feel your education was relevant? For me...not so much. Later I started to teach and do research but I still have this feeling. How do you feel about academia and the real world? Is academia part of the world we live in or just some "other place"..your thoughts?
Best wishes Henrik
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Reality is a holistic concept while academia is one of the partiality of the holistic reality. how can focusing a a small plant give you holistic view of a jungle for that one has to get out of the confinement of a plant and raise above the jungle to have a holistic view of the jungle. Unfortunately division of knowledge into thousands of disciplines have increased ignorance of reality,. I think its time to review the strategy of academia and move toward fusion of knowledge.
Please see the attachment it might convey what I want to say.
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Throughout the world many scientists/researchers, globally hard working to develop relevant drugs/medicines for the treatment of COVID19. Can anyone tell, if there is development, regarding?
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In India, few medicines have been approved on emergency basis for the treatment/management of COVID 19. You can visit www.cdco. gov.in
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Dear Scholars,
You all are well aware that COVID-19 has disrupted every aspect of our lives including K12 and higher education sectors. Keeping in view the WHO recommendations, nations are enforcing social distancing in all fields including primary, secondary, higher secondary and university education. If we think positively, then this culprit COVID-19 is a blessing in disguise as the people are now taking care of personal hygiene, cleanliness of their surroundings and trying their best to improve their immunity. Besides educational institutions are reaching to the students.
During the past three months, the schools and universities around the globe have extended their outreach from a confined classroom to the students` bedrooms. Now the students can learn with more flexibility without wasting their times in travelling to their respective schools. The online mode of education has proven fruitful as it has lead to reduce institutional expenses which they had been spending on building & maintenance of infrastructure, electricity, furniture, multimedia and computing equipment. There is likelihood that tuition fee may be reduced with time if the situation prolongs (god forbid).
Apart from the above facts, I personally believe that online mode of education can not replace laboratory and clinical training of students who are pursuing their undergraduate studies in medicine, dentistry, engineering and such other technical fields.
What do you think? Will this batch of undergraduate students who are learning through online media i.e. LMS, Zoom, Webax etc, be able to acquire the professional competencies required in their respective fields. If the answer is no, then how can we utilize online platforms to ensure delivery of the quality education and achievement of course and program learning outcomes?
Thank you .
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Well said
Zorica Popović
I especially like the phrase "Mission Impossible"...
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The big five personality trait model ( McCrae & Costa) describes 5 bipolar dimensions of personality. The model received some criticism but is still generally accepted and perhaps it is the only descriptive model of personality that is "widely" accepted. What do you think are the strengths and weaknesses of this model? Is it complete or not? If not, what is missing?
Best wishes Henrik
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Dear Dr.Samah Zahran,
Please, add money to your greatest assessment for personality perspective..
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I understand vaguely that the first author is supposed to be the one who "did the most work", but what counts as "work" in this comparison? Does "most" mean "more than all the other coauthors together" or just "more than any other coauthor"? What happens when the comparison is unclear? How often is "did the most work" the actual truth, versus a cover story for a more complex political decision?
I realize that the precise answer is different for every paper. I'm looking for general guidelines for how an outsider (like me) should interpret first authorship in your field. Pointers to guidelines from journals or professional societies would be especially helpful.
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Welcome Frank T. Edelmann
Another important attached concept is:
1. Principal Investigator (PI) usually after the name has ** PI
2. Co-Principal Investigator or Co-Investigator (Co-PI/Co-I)
3. Faculty Participant
Traditionally, the last author position is reserved for the supervisor or principal investigator. As such, this person receives much of the credit when the research goes well and the flak when things go wrong.
Multiple “first” authors. Additional “first” authors can be noted by an asterisk or other symbol accompanied by an explanatory note. This practice is common in interdisciplinary studies; however, as we shall explain further below, the first name listed on a paper will still enjoy more visibility than any other “first” author. https://wordvice.com/journal-article-author-order/
Multiple “last” authors. Similar to recognizing several first authors, multiple last authors can be recognized via typographical symbols and footnotes. This practice arose as some journals wanted to increase accountability by requiring senior lab members to review all data and interpretations produced in their labs.
For details please read attached PDFs
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50 percent of physicians joined the Nazi party. For some reason, they were more enthusiastic than other professions to collaborate with Nazis. Other professions did not have such high representation in the Nazi party.
I wonder about the possible reasons for that enthusiasm.
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  • Udo.Hennighausen@web.de: I feel that there are several reasons. 1871 the Jewish citizens got full citizen rights in Germany (the Deutsche Reich) and many of them started an academic career. At the same time, in the last third of the 19th century, a latent antisemitism rose in Germany, in all levels of the society. The work in a hospital may be compared with the work on a ship, the leading physician, often professor, had a right to order similar to the captain of a ship. This military thinking might have been one cause for the adherence to NS. Also many medical students at that time were members of academic corporations (Burschenschaften, Landsmannschaften, Corps etc.), where also authoritarian rules were lived. Perhaps doctors were jealous on the job-positions of Yewish doctors, as after 1871 many Germans of Yewish heritage or faith started a successful academic career or profession in private practice. Rebecca Schwoch (Hamburg) has done a great research work about the fate of the doctors of Yewish heritage or faith in private practice with licence for social insurance, who worked in Berlin: About half of the doctors in private practice with licence for social insurance in Berlin were of Jewisch faith or heritage. Another point is the idea of eugenics, half science, half ideology, which was discussed in all countries at that time and was cultivated be NS-ideology.
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Hello, dear fellow scholars.
I'm writing this post after the advice that I received to bring to your knowledge a lesson that I'm learning yet at the beginning of my academic career.
I'm one of the authors of a case report that has been published by the journal 'Archives Of Medicine' without our consent¹. Before the case report has been published, we have sent a formal e-mail soliciting to the editors the withdrawal of our intention to publish, because we have found that the journal was being investigated due to suspicious activities².
I'm currently a 3rd-year medical school student and this was the first time that we have submitted an article to a journal (me and my colleague, which also is a 3rd-year medical school student). I'm mentioning this just to contextualize the fact that we are pretty much beginners in the matters of scientific publications and we never even imagined that such thing as "predatory publishers" exist.
When we started to look for journals to publish the case report, we were looking for a cost-free journal, but at the time we submitted the article to the Archives of Medicine, by an honest mistake and lack of attention, we didn't realize that this journal has a publishing fee, and a few days after we had submitted the case report we received an e-mail with a charging bill of over 1,500 euros.
Immediately after receiving this e-mail, we started to write a formal message to the editorial board, explaining to them about our mistake, apologizing for the inconvenience, and soliciting the withdrawal of the intent to publish the case report. Also, we got suspicious by the fact that this charging form was asking for sensitive financial information (like credit card number, CVV number, and other info).
In the meantime, we came across a post (here in Research Gate) mentioning the suspicious activities about the IMedPub² (the group responsible for the Archives of Medicine). As soon as we found out these facts, we sent the e-mail formally soliciting the withdrawal of the intent to publish the case report. However, a few days later as I've mentioned at the beginning of this post, the journal published the case report¹ without our consent and ignoring our solicitation. We have only completed the initial forms for starting the publishing process and send them the manuscript by completing the on-line form but we didn't make any payment for the publication fee since we sent this e-mail soliciting the withdrawal of the submitting intention (even though, the journal published it anyway).
¹https://www.archivesofmedicine.com/medicine/atypical-case-of-chronic-granulomatous-disease-a-case-report.pdf
²https://www.researchgate.net/post/Can_I_trust_OMICS_iMedPub_Conference_Series_Allied_Academies_Pulsus_Trade_Sci_SciTechnol_and_EuroSciCon
All this post was originated by the concern about the fact that our names are now associated with an article published by a journal that was under the accusation of suspicious activities and how this could affect our academic reputation and professional future.
We have received some advice to turn the situation public here in Research Gate to other researchers to learn from this lesson and also to hear your opinion. We'll appreciate it if you let us know your perspective about the case and if you can advise a better way of how to resolve this situation.
I apologize for this enormous text, but I think it was necessary to explain the whole situation with some more detail.
If you want to know more details about the original post, the link is the following: https://www.researchgate.net/post/How_to_proceed_in_cases_of_violation_of_copyright
Thanks for your attention.
Best regards,
Wilian Sant'Ana
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Thank you for the tip! Surely I'll add it to my checklist next time.
Regards.
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The development of a vaccine for COVID-19 has become a battleground for many countries to prove to the world/their own peoples that their technology is superior and better than the competitors at the international stage. it is always a point of concern when science is serving the political establishment. Russia claimed that they have developed 'the first' Covid-19 vaccine. WHO is raising concern about the validity of this claim and urging Russia to provide sufficient data to back this claim.
Is it possible for the same scenario to be repeated in the US? An election is near and COVID-19 vaccine development can influence the result.
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Is Russia's COVID-19 trials akin to "Haste makes waste"?
Russia's COVID-19 vaccine has not gone through the mill as some other vaccines, the front-runners being Chinese vaccine which is undergoing phase 3 trials in China, Brazil, Saudi Arabia and Pakistan, Oxford Astra-Zeneca vaccine, also in phase 3 trials, and Moderna's US vaccine.
I will just say regarding Russia's COVID-19 policy "Haste makes waste"
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Indeed, I have observed that there is some scientific journals that listed in Scopus sources of not good quality from scientific point of view. At the same time some Universities are depending on Scoups in a similar manner to that of Thomson & Routers or Clarivate analytics.
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LanguagesEnglishAccessProvidersElsevierCostSubscriptionCoverageDisciplinesLife sciences; social sciences; physical sciences; health sciencesTemporal coverage2004–presentGeospatial coverageWorldwideNo. of records69 millionLinks
  • Website
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COVID-19 is changing the social life of all people. Jumping out of the personal aspect, how does it affect the family as a whole.
Family is regarded as the fundamental structure of the society, will COVID-19 changes the future family structure, unit and model?
How is it affecting gender issues too?
Besides, why is domestic violence increasing? Is psychology and psychiatry playing a role?
reference:
[1] Campbell AM. An increasing risk of family violence during the Covid-19 pandemic: Strengthening community collaborations to save lives.
Forensic Science International: Reports vol. 2 (2020): 100089.
[2]COVID-19: Reducing the risk of infection might increase the risk of intimate partner violence
EClinicalMedicine
[3]The pandemic paradox: The consequences of COVID‐19 on domestic violence
J Clin Nurs
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Effect of lockdown is domestic violence increasing day by day.
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Many studies and analyes we do require statistics to back up. However, many times the results run out to be statistically significant, yet when interpret it in the clinical context, it is too small to be significant.
This is rather frustrating. Any solution for solving this?
Is those very small interval unit scale more easily affected?
Can we change our analytics method to cope with the results?
Beyond statistical significance: clinical interpretation of rehabilitation research literature.
Int J Sports Phys Ther. 2014;9(5):726–736.
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Good question
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Are immunity enhancer medicine (Homeopathic and Ayurvedic ) helpful to prevent yourself from Corona virus?
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AYUSH Remedies - Approved by Govt of India to fight against Covid19 - The basic
concept is to boost up the immunity - https://www.researchgate.net/deref/https%3A%2F%2Fwww.mohfw.gov.in%2Fpdf%2FImmunityBoostingAYUSHAdvisory.pdf - as advised by Ministry of Home Affairs ( MoHFW ) , India .
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In a paper deposited in BioRxiv entitled: "Susceptibility of ferrets, cats, dogs, and different domestic animals to SARS-coronavirus-2" the team from Harbin Vet Institute intentionally infected several species of animals including cats with SARS-CoV-2. The results showed that the virus was transmitted between the cats, but no sympthoms of COVID-19 were observed.
This result is interesting in terms of an observation made by a medic from Spain - Sabina Olex-Condor that from the 100 patients serious with COVID-19 that she examined there were no cat owners. She suggested as a hypothesis that due to cross-immunity (cats are a known reservoir of coronaviruses) cat owners have milder sympthoms of COVID-19.
I'm aware that the paper from Harbin Institute is a pilot study, has many possible dead ends and limitations. I'm also aware that this cross-immunity hypothesis suggested by Sabina need serious assement due to limited number (and problalbly non-representative set) of patients.
Do you think that this is possible in terms of knowledge of human immunology? If the above is met do any of you have access to indepth demografic (?) data of people infected with SARS-CoV-2 to check this hypothesis?
Disclaimer: not an expert in medicine or veterinary, I study plant genomics, this is pure scientific curiosity.
I hope that your families and friends are well.
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Various medical institutes are making their efforts in preparation of vaccine for Covid-19 disease. The medical trials are lengthy in process, how much time it will take for fullproof vaccine for the disease. Please express your views. Thanks
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Ravindra S Bankar "The medical trials are lengthy in process..." The trials are extremely, and, under normal circumstances, irresponsibly short! By the way, most vaccines fail in phase III trials.
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I am a Brazilian psychiatrist with a master degree in preventive medicine. This year I will coordinate an academic ambulatory for medical students. I would like to teach deprescribing in psychiatry. The students are in the final year of medicine degree, and they will spend one month in this ambulatory. The ambulatory is part of a primary care setting which don’t have psychiatrists or other specialists. So, my major difficult is how to select patients? Which patients would benefit of this approach? Anyone has previous experience or suggestion??
Thank you!
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I feel there are two phases involved in this.
1) Deprescribing safely (following protocols so as to avoid acute withdrawal) and appropriately (are we talking episodic depression/situational anxiety...or schizophrenia, bipolar disorder, etc that can be of higher risk to or generally more difficult to treat without medications)
2) Treating the root cause underlying the diagnosis so as to deprescribe sustainably. This, of course, requires an understanding that these psychological symptoms are not “normal” and therefore have a reason for their existence that can be treated. Although physicians are not often familiar confident with rendering forms of therapy such as cognitive behavioral therapy, body psychotherapy, among others, half the battle is having real conversations with the patient regarding the nature of the problem (childhood abuse, specific triggers, chronic pain, etc). As a brilliant medical school professor once told me, “If you listen to the patient long enough, they will tell you the diagnosis.”
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How to remove toxic heavy metal traces like mercury, lead, cadmium etc. from solid herbal material or food material?
is there any specific methodology or technique to remove metal traces from solid material like food or plant herbal material?
so that after removal of metal, the solid material can be used as food or medicine.
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Solid herbal material or food material when manufactured, their composition already analyzed including its metals content , so there are no toxic metals exist to the composition of Solid herbal material or food material.
Normally, heavy metals removal processes are bio accumulation and bio-absorption, by plants .
I studied on bio accumulation and bio-absorption of heavy metals by seaweeds. It shows seaweeds actively bio accumulate and bio-absorb of heavy metals from water and sediment.
Other literature reports regarding bio accumulation and bio-absorption of heavy metals other plants.
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Empirical use of non-harmful drugs for patients is superior to evidence-based medicine ... or not
Does anyone use famotidine in COVID?
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I should probably also add that in addition to the increased risk for COVID-19 infections, using the drugs may increase the risk of other gastrointestinal infections for other pathogens. This would increase overall pathology as well as risk for any of these infections. Nutritional damage and other effects may also occur, even if not severe.
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I am starting a systemic review. And it's my first one. I have figured out the PICO and search keywords. I am overwhelming with massive results from different search engine. They contains duplicates. What is the best practice to combine all the result and remove duplicates.
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There are various tools such as EndNote, RefWorks, Mendeley, Rayyan, Zotero, Covidence and others. Covidence is a good option for undertaking Cochrane systematic reviews, but it is not free to use. Covidence is free for those authoring the Cochrane reviews.
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Can we use artificial intelligence technologies such as Machine Learning and Deep Learning to help in finding medicine or vaccine for COVID-19. Any ideas?
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Yes! Please see the RG link below.
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What are the most important factors to considered when thinking about the cities of the future? What scholars to involve? Or, can we even leave some academic discipline behind and not include them in discussion?
This is just a teaser for an upcoming conference...
Theology in Rijeka and the Department of Philosophy of the Catholic Faculty of Theology at the University of Zagreb, the Department of Social and Human Sciences in Medicine at the Faculty of Medicine of the University of Rijeka, the Faculty of Health Studies of the University of Rijeka and Faculty of Theology at University Nicolaus Copernicus, Toruń (Poland) - organize an international symposium, titled „The City of Future: Anxiety of Expansion“, which will be held on November 13, 2020 (Friday) in the Theology Building (Rijeka, Omladinska 14).
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One of the most important factors to ensure world peace is for city governments to prioritize good planning for the future, including conducting many scientific studies and investigations to determine short-term objectives and long-range goals.
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The situation is going worse and the health system in IRAQ is so poor to provide the simplest treatment needs of patients. What should we do in such a horrible situation?
Is there advice that should we follow to stay safe and healthy until they come up with the vaccine of COVID-19.
How to make our immunity stronger in this situation, what should we eat? what should we drink? what kind of medicine should we have to have at home?
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I am interested in how people and cultures view practitioners and supporters of Nutraceuticals. For generations, food or plant based substances have been used as a treatment for disease. The pharmaceutical industry has replaced grandma remedies. Charlatans have given the herbal drug industry a bad name. True believers of herbal cures though have also stretched the public's faith with cures for baldness to cancer and now to Covid-19.
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Thank you for your thoughtful answer. There is so much to learn and it is so easy to scoff at that which we do not understand. Continued success with your mission.
brigid
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my value of sample is greater than that of standard and when I consider the formulas such as
(1) Percentage inhibition = (Abs Control – Abs Sample) x 100 / Abs control
(2) % Inhibition=100 − (A1-A2)/A0)*100)
(3) % Denaturation inhibition = (1−D/C) ×100%
Where D is the absorbance reading of the test sample, and C is the absorbance reading without test sample (negative control).
(4) PERCENTAGE INHIBITION = [100-(OPTICAL DENITY OF TEST SOLUTION – OPTICAL DENSITY OF PRODUCT CONTROL) ÷ (OPTICAL DENSITY OF TEST CONTROL)] ×100.
Which can be correct????? If I put control first ie, rewrite (3) as
% Denaturation inhibition = (1−C/D ×100% Getting % otherwise percentage is exceeding 100.
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I recommend you to read from the following reference source
Kırmusaoğlu, S. (2019). The methods for detection of biofilm and screening antibiofilm activity of agents. In Antimicrobials, Antibiotic Resistance, Antibiofilm Strategies and Activity Methods. IntechOpen.
However, I think this might help.
To interpret results, categorization can be done as no biofilm production (0), weak (+ or 1), moderate (++ or 2), and strong biofilm production (+++ or 3) by the calculation of cutoff value (ODc) shown below:
  1. OD ≤ ODc no biofilm production
  2. ODc< OD ≤ 2 × ODc weak biofilm production
  3. 2 × ODc< OD ≤ 4 × ODc moderate biofilm production
  4. 4 × ODc< OD strong biofilm production