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What is In Vivo Microscopy (IVM) images?
I'm not clear about this term, can anyone please point out it?
Any ideas and resource links are much appreciated🖤
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Please refer to the article attached. It may be helpful.
Best.
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Metabolic rewiring and epigenetic remodeling, which are closely linked and reciprocally regulate each other, are among the well-known cancer hallmarks. Studies have reported use of Onco-metabolites to metabolically reprogram the epigenetic of cancer. I was wondering what might be major limitations of such techniques?
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Immunometabolism maybe need more attention.
Some therapeutic targets for tumor cells would have impacts on tumor immune microenvironment. Recently, I stimulated myeloid cells with some molecular drugs potential to target tumor metabolism. These drugs also reprogram metabolism of myeloid cells and cause immunosuppression.
Tumor metabolism frangibility should boost immune surveillance. Thus, it still need to seek for special metabolism targets and pay more attention on tumor immunometaboism.
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I am thinking about adapting neuroscience tools for identifying the patient’s reactions in making the diagnosis. I know there is a debate, but I cannot find any literature. Could anyone help me?
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Hi Liliana,
Yes, you are right. There is a plenty of discussion in this area. Please find below some guidelines.
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Hello, good day.
Please I'm working on a project which needs a "review of relevant theories" of the study "medical negligence behavior"
I found 2 theories relating to this study (conflict theory and theory of negligence), but they are not enough.
Please can I get more theories concerning medical negligence?
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There are four legal elements which must be proven: a professional duty owed to the patient; breach of such duty; injury caused by the breach; and (4) resulting damages.
In general, malpractice claims are adjudicated in state courts according to laws (e.g., USA), which typically require three elements for a successful claim: the patient suffered an adverse event; the provider caused the event due to action or inaction; and 3) the provider was negligent, which essentially entails showing that the provider took less care than that which is customarily practiced by the average member of the profession in good standing, given the circumstances of the doctor and the patient. Collectively, this three-part test of the validity of a malpractice claim is known as the “negligence rule.” In theory, this rule should provide compensation to iatrogenically injured patients and lead doctors to take appropriate precautions against accidental harm. In practice, however, the rule performs poorly on both dimensions.
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European Society of Medicine invited me to particitate My article in their conference
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Dear Rafi Al-Ani Do have a look at the following discussion here on RG: https://www.researchgate.net/post/Beware_of_these_kinds_of_emails
Conclusion: avoid.
Best regards.
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Your recommendation and assumes! Please
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please eloborate what you mean by bloodlessness ? If you are talking about anemia, then a balanced diet and vitamin supplements are needed.
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I started my studies on histology and I realized most of well established text-books don't use scale bars in their images, except the books of the American-German Thieme Publishing Group. I think it is a lack of technical rigorosity, even though most of books treat the issue only on a qualitative point of view. So, what do you think about that? Should the publishers in that area change their concept to increase their accuracy?
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(only one point). maybe there is a difference to state how the image was made and how the scale could be, even though the scale bar is almost approximately at the same level each time. STM, (scanneling Tuning Microscope, false colour, the blacvk and white images, maybe the microscope taken with this 10x, objectives, and so on.All these give ideas on how the scale bars are.... even though I think it is ignored data.
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Vertigo is a condition that can make it feel like you or your surroundings are spinning, sometimes leading to a loss of balance, according to the U.S. National Library of Medicine.
Coronavirus 2019 or COVID-19 is a novel entity which had led to many challenges among physicians due to its rapidly evolving nature. Vertigo or dizziness has recently been described as a clinical manifestation of COVID-19.
So, Are dizziness and vertigo COVID-19 Symptoms? and why?
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Does anyone knows where can I publish study protocols?
in a field of emergency medicine and psychology
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You can publish your study protocols in any of the journals which has scope of your title. Example: BMC, BMJ Open, Clinical Trials,… etc.
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Applications of bioinformatics in medicine is a key factor in technological advancement in the field of modern medical technologies.
In which areas of medical technology are the technological achievements of bioinformatics used?
What are the applications of bioinformatics in medicine?
Please reply
I invite you to the discussion
Thank you very much
Best wishes
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Please have look on our(Eminent Biosciences (EMBS)) collaborations.. and let me know if interested to associate with us
Our recent publications In collaborations with industries and academia in India and world wide.
Our Lab EMBS's Publication In collaboration with Universidad Tecnológica Metropolitana, Santiago, Chile. Publication Link: https://pubmed.ncbi.nlm.nih.gov/33397265/
Our Lab EMBS's Publication In collaboration with Moscow State University , Russia. Publication Link: https://pubmed.ncbi.nlm.nih.gov/32967475/
Our Lab EMBS's Publication In collaboration with Icahn Institute of Genomics and Multiscale Biology,, Mount Sinai Health System, Manhattan, NY, USA. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/29199918
Our Lab EMBS's Publication In collaboration with University of Missouri, St. Louis, MO, USA. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30457050
Our Lab EMBS's Publication In collaboration with Virginia Commonwealth University, Richmond, Virginia, USA. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27852211
Our Lab EMBS's Publication In collaboration with ICMR- NIN(National Institute of Nutrition), Hyderabad Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/23030611
Our Lab EMBS's Publication In collaboration with University of Minnesota Duluth, Duluth MN 55811 USA. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27852211
Our Lab EMBS's Publication In collaboration with University of Yaounde I, PO Box 812, Yaoundé, Cameroon. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30950335
Our Lab EMBS's Publication In collaboration with Federal University of Paraíba, João Pessoa, PB, Brazil. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30693065
Our Lab EMBS's Publication In collaboration with collaboration with University of Yaoundé I, Yaoundé, Cameroon. Publication Link: https://pubmed.ncbi.nlm.nih.gov/31210847/
Our Lab EMBS's Publication In collaboration with University of the Basque Country UPV/EHU, 48080, Leioa, Spain. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27852204
Our Lab EMBS's Publication In collaboration with King Saud University, Riyadh, Saudi Arabia. Publication Link: http://www.eurekaselect.com/135585
Our Lab EMBS's Publication In collaboration with NIPER , Hyderabad, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/29053759
Our Lab EMBS's Publication In collaboration with Alagappa University, Tamil Nadu, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30950335
Our Lab EMBS's Publication In collaboration with Jawaharlal Nehru Technological University, Hyderabad , India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/28472910
Our Lab EMBS's Publication In collaboration with C.S.I.R – CRISAT, Karaikudi, Tamil Nadu, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30237676
Our Lab EMBS's Publication In collaboration with Karpagam academy of higher education, Eachinary, Coimbatore , Tamil Nadu, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30237672
Our Lab EMBS's Publication In collaboration with Ballets Olaeta Kalea, 4, 48014 Bilbao, Bizkaia, Spain. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/29199918
Our Lab EMBS's Publication In collaboration with Hospital for Genetic Diseases, Osmania University, Hyderabad - 500 016, Telangana, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/28472910
Our Lab EMBS's Publication In collaboration with School of Ocean Science and Technology, Kerala University of Fisheries and Ocean Studies, Panangad-682 506, Cochin, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27964704
Our Lab EMBS's Publication In collaboration with CODEWEL Nireekshana-ACET, Hyderabad, Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/26770024
Our Lab EMBS's Publication In collaboration with Bharathiyar University, Coimbatore-641046, Tamilnadu, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27919211
Our Lab EMBS's Publication In collaboration with LPU University, Phagwara, Punjab, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/31030499
Our Lab EMBS's Publication In collaboration with Department of Bioinformatics, Kerala University, Kerala. Publication Link: http://www.eurekaselect.com/135585
Our Lab EMBS's Publication In collaboration with Gandhi Medical College and Osmania Medical College, Hyderabad 500 038, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27450915
Our Lab EMBS's Publication In collaboration with National College (Affiliated to Bharathidasan University), Tiruchirapalli, 620 001 Tamil Nadu, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27266485
Our Lab EMBS's Publication In collaboration with University of Calicut - 673635, Kerala, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/23030611
Our Lab EMBS's Publication In collaboration with NIPER, Hyderabad, India. ) Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/29053759
Our Lab EMBS's Publication In collaboration with King George's Medical University, (Erstwhile C.S.M. Medical University), Lucknow-226 003, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/25579575
Our Lab EMBS's Publication In collaboration with School of Chemical & Biotechnology, SASTRA University, Thanjavur, India Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/25579569
Our Lab EMBS's Publication In collaboration with Safi center for scientific research, Malappuram, Kerala, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30237672
Our Lab EMBS's Publication In collaboration with Dept of Genetics, Osmania University, Hyderabad Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/25248957
Our Lab EMBS's Publication In collaboration with Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Hyderabad Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/26229292
Sincerely,
Dr. Anuraj Nayarisseri
Principal Scientist & Director,
Eminent Biosciences.
Mob :+91 97522 95342
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Reality may increasingly hurt – #Genomic #targetedtherapy
Changes between 2006 and 2020
-eligibility from 5.13% to 13.60% *only*
-response from 2.73% to 7.04% *only*
The authors use in their discussion different paraphrasing: “the percentage of eligibility for and response to genome-targeted drugs increased 54% and 28%, respectively
which from the objective point of view is correct, but this implies a major improvement, although the reality of inefficiency is different
Some may state *the house of cards collapse of the breakthrough* ?
Otherwise today's basics of biotechnological power politics in created hypes of landmarks, breakthroughs, which might be seen in the accordance of the Latin epic poem, The Aeneid by Virgil:
parcere subiectis, et debellare superbos’ (I believe it at any rate)
References
Article Haslam et al. (2021) Ann Oncol 2021, DOI 10.1016/j.annonc.2021.04.003
The Aenedid from Virgil Vergil (19 BC), Aeneis, Liber sextus, Vers 847-853.
#medicine #health #medicalsciences #breakthroughs #landmarks #hallmark #hype #criticalthinking
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Dear Pr Brücher,
Thank you for sharing with us these useful informations.
Best regards,
Pr Hambaba
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Under COVID-19, healthcare facilities requests a lot of sterilization to prevent hospital transmission of the disease. Bleach solution and many other disinfection agents may not be effective against such a large scale of usage.
Can ultraviolet light be used to inactivate the virus?
Can it be applied on whole room disinfection?
Can it be used on high turnover medical equipment sterilization? E.g. stethoscope.
Can it be used to inactivate infected donors' blood products or body fluids?
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It's 99 days since the first case of COVID-19 in Hong Kong, and we are welcoming the 5th days of 0 new cases of COVID-19 following a week of <10 cases per day.
How should we define the end of a local endemic?
How long should the latent period be defined?
When is it safe to resume social activities?
Should territory wide screening of asymptomatic people be done before declaring the end of endemic?
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The SARS-CoV-2 (Covid-19) coronavirus pandemic is a global epidemic. On a global scale, the state of the pandemic in March 2020 was announced by the World Health Organization. Therefore, this organization could declare the end of the pandemic. On the other hand, the end of the epidemic on a regional, national or local scale can be announced by national central institutions of the health care system, including the ministries of health, in agreement with the government. In order to be able to declare the end of the epidemic on a national, regional or local scale, it is necessary to have a relatively large decrease in the number of new coronavirus infections, a decrease in the number of people seriously ill with Covid-19 disease and deaths caused by this disease. The decrease in Coronavirus infections and in sick people should be sustained in a longer period, i.e. min. several months, taking into account the periods of possible occurrence of subsequent epidemic waves caused by new variants of the Coronavirus and occurring in other regions of the world. In addition, an important factor that may be taken into account in the event of declaring the end of a pandemic on a global scale or an epidemic on a regional scale will be the level of vaccination of citizens with highly effective vaccines against Coronavirus and the level of social, collective immunity of the society achieved thanks to these vaccines.
Best regards,
Dariusz Prokopowicz
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We are compiling comprehensive details for traditional medicines and their marketing approval in a particular country. For now, we are reviewing Kampo Medicines of Japan. But somehow we are not able to get suitable guideline documents (original from Japanese Regulatory Agency's Website). Can anyone guide us? From where we can find guidelines for marketing approval of Kampo medicine in Japan?
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How can you decide the judgment on a specific article whether it is good or not, is your judgment depends on the title of the article or the abstract or the publishing journal or something else?
Please, share us your opinions about the discussion
Thanks
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I think depends on
1. Quality of Journal which depends on citations, Quartile, Indexing, Impact Factor etc.
2. Novelty
Regards
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COVID-19 is mainly a respiratory disease that affects the lung, although other organ structures with endothelium seems to be affected too.
When should we do imaging?
What is the aim of the imaging?
How can it help with management?
Do you agree with the following consensus statement?
How will you adjust your own practice and difficulties encountered? Why?
Ref:
The Role of Chest Imaging in Patient Management during the COVID-19 Pandemic: A Multinational Consensus Statement from the Fleischner Society. Chest. 2020 Apr 07.
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I have watched a child crying loudly in pain, while collecting blood for testing. Can we develop a technique which can collect the blood or inject a medicine to children in a complete pain-free way ?
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Thanks you, dear Dr.Mark Louis Weiss
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Iam a dental student and i want to increase my knowledge in writing drug chart to patient in the future, can you give me some advises to increase my knowledge in this field, i the name of drug and the number of dose is very consued and i forgot it fast so how the doctors write it easy...... So can you advise me to be good in the future
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dentistry needs only few drugs to be remembered, procedures like extractions and root canal need common antibiotics, to follow empirical use pls know few gram positive acting drugs and some mixed infection drugs, we use anti amoebic drugs as well. anti- inflammatory and analgesics are routinely used, need to remember few of it. Beware of drug interactions especially metronidazole should not be taken along with alcohol
some emergency drugs like hematinics, to stop bleeding and anti allergic drugs should be learned
for oral lesions need to know about anti oxidants, and few local steroids ointments, some gum paints and aesthetic gels for pain relief
as a beginner if you know these you get confidence
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Hello, I will try to produce Sb2S3 films with thermal evaporation technique using Sb2S3 pellets or Sb pieces. Then I will complete the production with thermal annealing. Could you please give information about the risks of Sb2S3 pellets or Sb pieces and the precautions I should take?
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Deep Reinforcement Learning Training course
Time: January 15-January 18
DeepLearning Training course
Time: January 27-January 30
(Report for three days on the first day; Deploy the computer test in advance)
III. Lecture 1:
Course 1. Introduction to Intensive Learning
Course 2. Strengthen the foundation of learning
Course 3. Deeply strengthen the foundation of learning
Course 4, Multi-agent Deep Intensive Learning
Course 5. Multi-task deep intensive learning
Course 6. Strengthen learning and application
Course 7. Simulation Experiment
Course 8. Supplementary courses
IV. Lecture 2:
Lesson 1: Tensorflow Beginners to Proficiency:
Lesson 2: Image Classification:
Lesson 3: Object Detection:
Lesson 4: Face Recognition:
Lesson 5: Algorithm Implementation:
1. Convolutional neural network CNN
2. Circulating neural network RNN
3. Strengthen learning DRL
4. Antagonistic generation network GAN
5. Transfer learning TL
6. Specific examples of practical medicine, remote sensing images, oil exploration and intelligent transportation
Contact person: Li Luxin (teacher)
Mobile phone: 13311241619
QQ: 1942892948 (same as WeChat)
Strengthen learning QQ exchange group number: 872395038 (add group remarks: Li Luxin invited)
Deep learning-distance online course QQ group number: 1057802989 (plus group remarks: Li Luxin invited)
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Interesting
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Under the pandemic of COVID-19, screening becomes important to tackle the spread. Fever is one of the screening criteria for many public places screening for access.
However, how is fever defined?
Is the 0.1 degree change makes the significance?
What is the range of standard deviation being acceptable?
What machine is accurate?
Is those hand held infrared measuring machines reliable?
Is there scenarios giving false negative tha may make a huge consequence?
Normal Body Temperature: A Systematic Review.
Open Forum Infect Dis. 2019;6(4):ofz032. Published 2019 Apr 9.
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CDC considers a person to have a fever when he or she has a measured temperature of 100.4° F (38° C) or greater, or feels warm to the touch, or gives a history of feeling feverish.
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I know that an infant's brain can repair itself when damaged but why doesn't the same happen in adults after stroke or brain injuries?
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With Regenerative Medicine, using stem cells, the ongoing Programs are doing it, with good results and promising expectations.
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Dear seniors and researchers,
Briefly introducing myself, I am a fourth year medical student from Indonesia. Currently, I am performing a multiple logistic regression on several possible factors affecting medical student preference toward distance learning in this pandemic era. Honestly, it is my first time in using logistic regression in my work, and I might encounter several confusing issues regarding this statistical procedure. I have selected 14 eligible covariates for multiple logistic regression according to its significant p-value (0.000) during their simple logistic regression. After including all of those 14 covariates to the model, the ExpB (odds ratio) of all 14 covariates become insignificant despite decent model (Good result of Omnibus test, R-squared, and Holmer and Lemeshow test). All of statistical procedure were performed in SPSS ver 22.
Regarding this issue, what should I do in responding those finding? Is it correct to interpret that there were no significant relationship between all of 14 covariates and dependent variable (student preference toward distance learning) simultaneously? Or is there any suggestion of appropriate technical steps in conducting multiple regression analysis?
Thank You
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I'm assuming the pairs have correlation coefficient >= 0.7 (r=0.07 suggests little correlation).
If you have 3 distinct pairs, I would suggest eliminating one variable from each pair leaving the most significant ones in the set. After that, you can proceed with a stepwise regression, if needed.
Another possible solution would be implementing a dimension reduction technique (i.e. principal component analysis) to reduce the number of predicting factors.
If you require any further information, let me know.
Best wishes,
Francesco
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Dear Fellows
With the developing stories of the spread of COVID-19 all around the world, which has been declared as a pandemic by WHO recently, I am wondering, in how much time this virus would vanish from the surface of the Earth? Is there any scientific study available for this?
Please share your opinions.
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Todavía no se puede predecir q desaparecerá el Covid 19. Al parecer tendremos q convivir con él e inmunizarnos con las vacunas aprobadas por la OMS.
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The development of a vaccine for COVID-19 has become a battleground for many countries to prove to the world/their own peoples that their technology is superior and better than the competitors at the international stage. it is always a point of concern when science is serving the political establishment. Russia claimed that they have developed 'the first' Covid-19 vaccine. WHO is raising concern about the validity of this claim and urging Russia to provide sufficient data to back this claim.
Is it possible for the same scenario to be repeated in the US? An election is near and COVID-19 vaccine development can influence the result.
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Please also have a look at this useful link.
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comparative study to treatment ringworm in cattle between( chemical treatment and plant extraction treatment).
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This might be considered a worst case scenario.
Repeated strikes by such a virus would scythe defenseless new victims each time, leaving fewer and fewer survivors.
For the species to survive, humanity would have to evolve resistance or other means of survival.
Is such a virus possible?
How would its epidemic spread be modeled?
Has a virus like that occurred in the past?
How would we deal with such a virus in the future?
What strategies would defeat such a virus?
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Theoretically yes, but in the long run the human species would end up adapting its immune defense mechanisms and would survive ... yes, the cost in human lives would be incalculable in the short and medium term
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As I see that PROSPERO is specific in the field of medicine however my review is in the field of online education.
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I think it is not mendatory and I agree with @Shin Murakami
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As we know MSG is widely used food additive and acts as a flavour enhancer. It is also approved by USFDA as GRAS! But some controversy are there regarding clinical reports where the physiological illness was shown after consuming MSG. So, is MSG good or bad for health? Are there any research related conclusions?
Thanks & Regards
Asik Ikbal
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Studies providing the evidence of MSG toxic effects have raised the increasing interest in MSG intake as flavor enhancer. Neurotoxic effects in brain, obesity and metabolic defects, „Chinese restaurant syndrome“ and detrimental effects on sex organs are the most discussed in the connection with MSG intake. http://ibimapublishing.com/articles/JMED/2013/608765/
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Dear Colleagues!
I hope you are all doing well. I have a question to all of you. I love to teach and so far I have been teaching everything from international business, marketing, management to organisational psychology. I feel ambivalent towards this however.I love to teach and Im curious in my nature and what better way to learn new things than to teach? However I also feel that if I continue being a generalist It might also be bad since I risk loosing touch with my main specialisation.
What are your thoughts? Your experiences?
My speciality is this :
Best wishes Henrik and professor Hugo 3 months old who keeps me company when Im trying to work :-)
Ps stay safe.
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Teaching one subject is more scientific and it will give you more academic background.
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Although the interests that exist around health and PE have a good sense and meaning, they may not be as benign as, ironically, they think they are. So, what are the risks of Medicine dictating the aims of Physical Education?
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I Follow.
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Hello,
I would appreciate it if you suggest me some public twitter sentiment analysis dataset during COVID-19 pandemic
Best regards,
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Sentimental Analysis of COVID-19 Tweets Using Deep ... - MDPI
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Is there a complete tutorial for using EHR (Electronic Health Record)?
I mean extracting some data like how many people have specific symptoms?
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I don't think there would be a generic tutorial for analysing a EHR, they are all different and the software should provide help on how to search a topic. Unfortunately coding classifications systems are different across the world and within countries. See that there is considerbale variation of coding and quality. Not even HL7 is uniformly applied in the UK as a health data standard https://en.wikipedia.org/wiki/Health_Level_7 It's a difficult problem.
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I had a few students help me with a simple but time-consuming task. The data they helped with will be used in a scientific paper. The students are part of the Student Research Program (SRP) at my institution and they received a class credit for their work with me. Should I include these students as co-authors on the manuscript?
I also had a student volunteer help me on the same research project. The student did not get a class credit for their help. Should the student be a co-author on the paper?
Thank you in advance for your opinions/suggestions.
Monika Polczynska
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Co-authorship is not a form of reimbursement (in laboratories and research institutes, all co-authors receive a salary or grants, nevertheless...). If a persons has made a creative contributions, then they are a co-authors. If the work is technical - for example, reprinting a text, or measurements (without processing etc.), then - no. There is another form for highline such participation: acknowledgment.
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I found a reference to this distinction on pub med that dates to the 70s. Efficacy is how well a treatment or intervention works in ideal circumstances. Effectiveness is how well a treatment or intervention works in normal practice. Although there are many references to this distinction and discussions of why it occurs, nobody seem to mention the origins of this distinction. Furthermore, this distinction seems more accepted in general medicine than in behavioral health.
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Efficiency, efficacy and effectiveness: What is the difference between this triad of words? Peter Drucker - considered the father of modern administration - establishes a series of fundamental distinctions between them, which gives us conceptual clarity. In a colloquial way they are known as "The three E's", but how does one "E" differ from the other two; Drucker is obliged to quote again, with the appearance of what he called “knowledge work”, thus we have: Efficacy + Efficiency = Effectiveness
Efficiency: doing things well. Carry out a task looking for the best possible relationship between the resources used and the results obtained. Efficiency has to do with the "how." The model for improving efficiency is based on three basic pillars: people, processes and customers. And it is achieved with competent people or with capacities, attitudes, aptitudes, abilities and experiences. Fast, effective and continuous flows of activities are needed that add value to the product or service for the client with efficient processes, analyzing said activities and quality.
Efficacy: doing the right things; carry out tasks in the best way, leading to the achievement of results. It has to do with "what" things are done. Effectiveness is doing what is necessary to achieve or achieve the desired or proposed objectives.
Effectiveness: doing the right things well. In other words, the tasks that are carried out are carried out efficiently and effectively. It has to do with "what" things are done and "how."
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Ayurveda, TM of India, advises to avoid Curd intake in diseases that have Kapha dosha predominance like Diabetes, Respiratory problems; in diseases arising out of Raktha dusti (Blood tissue vitiation) like Skin diseases and also in conditions where the digestive fire (Agni) is weak like during Night time. Regarding this Curd advisory, Ayurveda has very clear fundamental concepts and the findings of which have also been noticed in clinical practice as well.
Here I want to know are there any other Traditional system of medicine which has similar or any other observation about Curd intake?
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Sir! in the ayurvedic text a wide description is available related to curd. use of curd in relation to seasons when to eat or when not to eat. it is also described when to eat on daily basis, with the mixing of other substances. these all are for healthy individuals.
in some cases it is contraindicated because of its property.,
I don't think such a huge description will be available in other traditional medicines.
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I read that diabetic retinopathy can affect people with type 1 and 2 diabetes, especially those who have uncontrolled blood sugar and have diabetes for a long time. How can uncontrolled blood sugar cause diabetic retinopathy? and how is the treatment for diabetic retinopathy patients? thank you.
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Is it completely dependent on the region that patient lives in? If so, I'm specifically interested in the Southern California (United States) region.
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Globally, Candida albicans is the most prevalent species associated with invasive candidiasis; however, the distribution of non-albicans Candida spp
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It would be great if we get information regarding this from all around the world. Like we have Ashwagandha (Withania somnifera) in Ayurveda, Indian system of Medicine.
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Interesting discussion to follow
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I am interested in how people/cultures view specific foods as cures or treatments for illnesses.
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Yes for sure and some foods act as medicine itself and the are wonderful results when we see the medicinal benefits of some of the foods.
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RNA vaccines follow a different strategy, without using any "real" component of the virus at all. Instead, researchers aim to trick the human body into producing a specific virus component on its own. Since only this specific component is built, no complete virus can assemble itself. Nevertheless, the immune system learns to recognize the non-human components and trigger a defense reaction. So May I ask, What are your opinions about the safety and efficacy of the BNT162b2 mRNA Covid-19 Vaccine?
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In connection with the development of technology, the current technological revolution, which Industry 4.0 information processing technologies find application in the development of medicine?
Please reply
Best wishes
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Dear P. K. Farayibi,
Yes, it is correct ICT information technologies turned out to be very helpful in the development of both specific techniques and medical instruments, e.g. in improving surgery, creating implants (3D printing) and also in improving organizational issues, digitization of databases containing patient data and remote systems patient registration via the Internet. Especially the latter issue proved to be very helpful during the SARS-CoV-2 (Covid-19) coronavirus pandemic.
Thank you, Best regards,
Dariusz Prokopowicz
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dear all,
i'am searching for some good reviews in the field of hydrogen use, hydrogen effect, hydrogen fuel technology in the field of sports and medicine.
please share your papers with me.
is there some research in the field of regeneration in sports and post operation in medicine?
is there some research in special sports like triathlon, canoe, swimming and lifting?
thanks.
beste regards
torsten
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Dear Torsten, here are more recent papers:
Alharbi AAD, Ebine N, Nakae S, Hojo T, Fukuoka Y. Application of Molecular Hydrogen as an Antioxidant in Responses to Ventilatory and Ergogenic Adjustments during Incremental Exercise in Humans. Nutrients 2021;13(2):459.
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Hello and regards, our study investigates the relationship between latent toxoplasmosis and psychiatric and psychological mental disorders. It is part of my research (Ashkan Latifi, postgraduate student of psychology at University of Tehran- Iran) in partial fulfilment of the requirements of my master’s degree. By filling in this questionnaire, you have been of great help to me and to those with toxoplasmosis. In addition, by optionally sharing your email with me, you allow me to inform you of any possible toxoplasmosis-associated psychological/psychiatric problems in you under the supervision of two professors of University of Tehran (Dr. Abbas Rahiminezhad, psychologist and Dr. Reza Rostami, psychiatrist) for free. You can participate in this study if you have latent toxoplasmosis (other than congenital toxoplasmosis) and are at least 18 years old. The approximate response time to the questionnaire is ten to fifteen minutes. Thank you in advance for your participation in this research.
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Sorry i don't have
I am sorry
Best regards
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Articles that share the history and development of medicine in the UK, any aspect of medicine and medical education.
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I have only researched the subject for the Portuguese colonies (Mozambique, East Timor, and Macao) but I have consulted several studies regarding the British and the French colonial empires. One of the books that I found interesting is:
SETH, Suman. Difference and Disease: Medicine, Race, and the Eighteenth-Century British Empire. New York: Cornell University, 2018 (you will find a generous bibliography and sources in this book).
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The triangular theory of love by Sternberg, characterises love in an interpersonal relationship using three different dimensions: intimacy, passion, and commitment.According to this theory different stages and types of love can be categorised by different combinations of these three elements. My question is this: does this model fully capture the essense of what we call love. Can love not also have other attributes, we can have feelings of love towards a person without having either commitment, passion or intimacy, some people are asexual for example and lack commitment, others such as teenagers lack the understanding of what love is. Do you agree with this theory or do you like me see problems associated with such a sharp division of element of human affects. Best wishes Henrik
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For a complete answer to this interesting question (without any desire for prominence or any petulance) you can read some of my contributions here in "RG", specifically the article "Desire and love: the unfinished man" in which the two "Triangular Models" on Love and ways to evaluate and measure them:
-That of John Lee, from the University of Toronto, which offers us a wide typology of the ways of loving, thus –based on a questionnaire to measure falling in love– has established three primary types of love that are quite independent from each other: - EROS , LUDUS and STORGE, Identifying three “pure” combinations of these primary types: MANIA, PRAGMA and AGAPE.
-And, above all, that of Sternberg in his "Triangular Theory of Love" that considers three primary components: INTIMACY, PASSION and COMMITMENT, one in each vertex of the triangle, thus giving rise to 7 possibilities: INTIMACY: Like, friendship and affection without commitment or passion. ROMANTIC LOVE: Intimacy plus passion, with feelings of proximity and outbursts of passion. PASSION: Love at first sight, fickleness, mental and physical excitement. FATUO OR FALSE LOVE: Passion plus commitment, lightning engagement and wedding before intimacy develops, which usually leads to failure- COMMITMENT: Decision that one loves another person without intimacy or passion, it is an empty love or of convenience. COMPANION LOVE: Commitment plus intimacy, it is a solid but not romantic friendship.
As expected, in real life all these elements are mixed, with COMPLETE or CONSUMED LOVE being the one that combines intimacy, passion and commitment, in the center of the triangle.
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Does anyone have soft copy of book "Epidemiology of Medicine" by Henneken. Please share.
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I am also looking for the same book too can you please share with me.tesfaneh.shimelis@aau.edu.et
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The extensive successful use in people of mRNA vaccines for Covid-19 suggests they mark a key scientific breakthrough with broad impacts. These breakthrough vaccines are notable for combining two advances examined for years in the laboratory: pseudouridine modified mRNA and its encapsulation in lipid nanoparticles. Pseudouridine has been used in nucleotides for years to stabilize and study key protein-nucleotide complexes (e.g. Parikh et al. Proc Natl Acad Sci U S A. 2000 May 9;97(10):5083-8. doi: 10.1073/pnas.97.10.5083. PMCID: PMC25785 ). In fact, Pseudouridine (Ψ) is the most abundant RNA modification and has been termed the 5th base of RNA (Front. Cell Dev. Biol., 16 March 2021 https://doi.org/10.3389/fcell.2021.628415). Similarly Lipid nanoparticles have been used and studied for over 20 years (e.g. Puri et al. Crit Rev Ther Drug Carrier Syst. 2009; 26(6): 523–580. PMCID: PMC2885142). Yet the combination of mRNA modification by N1-methylpseudouridine to increase safety and efficacy with lipid nanoparticles to encapsulate mRNA for its protection and delivery made the Covid-19 mRNA vaccines feasible. Importantly, this transformative combination seems applicable to other vaccines and approaches suggesting it is worth considering the many possible applications that may advance biotechnology and human health.
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I think the effect will be significant on the progress of treatment, and the world will witness the end of cancer in the future
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Do you have medical cooperatives in your country? What is your opinion about the possible models of cooperatives in medicine that are proposed in this article? -
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See attachment...we would benefit a great deal If such cooperatives can be initiated in Africa
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Students pursuing medicine are constantly exposed to the risk of mental exhaustion and the sequalae that follows, which affects their mental health adversely. What would you as an instructor do to make sure our students don't fall prey to mental illness?
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Anxiety disorders are one of the most commonly diagnosed mental health problems among students. Anxiety is what we feel when we are worried, tense or afraid – particularly about things that are about to happen, or which we think could happen in the future.
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Patented medicines are expensive making it difficult for the lower or middle class families to afford it. If a certain medicine is helpful to the society, what can the government do to regulate the market, so that the socio-economic surplus is as large as possible while not taking away the company's patented rights.
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The government does not directly regulate or negotiate the price of drugs. Instead, U.S. drug companies set their prices, but insurers and pharmacies determine how much patients pay out-of-pocket
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The field of life-science and mathematics are always intermixing with each other, however, the COVID-19 has brought them more closely than before. Many researchers have developed fractional differential equations in life sciences. For example anomalous diffusion in cell membranes, epidemiological models, etc. I am particularly interested to know if there are applications of fractional differential equations in medicine?
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In the past few years, fractional differential equations have emerged as a reliable blue and well-organized mathematical tool in studying many science and engineering occurrences. Research in fractional differential equations is multidisciplinary and is used in diverse fields such as control systems, elasticity, electric drives, circuits systems, continuum mechanics, heat transfer, quantum mechanics, fluid mechanics, signal analysis, biomathematics, biomedicine, social systems, bioengineering, management, financial systems, traffic flow, turbulence, complex systems, pollution control, and more.
The principal aims of this Research Topic are:
• To bring together mathematicians, scientists, and researchers working in fractional calculus and its real-world applications.
• To encourage the advancement of new computational techniques.
• To study important fractional differential equations arising in real-world problems.
• To expand new trends in the area of fractional differential equations and their real-world applications.
The collected research papers will provide a short but significant explanation of the most critical hot problems in fractional differential equations and their real-world appeal-world.
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It may be in your education and experience that you deal with the structure of organic medicines. Which combination do you think is most common in organic medicine?
For example, many drugs have carboxylic acid in their structure. In your opinion, which compounds play an important role in the structure of the largest number of drugs?
Thanks
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Dear Pejman Rahmani Nejad thank you for your interesting technical question. In addition to the useful link provided by Lukas Schulig please also have a look at the following relevant article entitled
Chemical Structure-Related Drug-Like Criteria of Global Approved Drugs
The paper is freely available as public full text on ResearchGate. According to this article "the most common functional group is the hydroxyl, as its occurrence frequency in all databases is the top one. Moreover, -COOR or -COOH are the second most common functional groups."
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AI showed its promise in many fields, but most of researches in AI application on medicine is still "proof-of concept". So how do clinicians feel about AI? What are clincians' concerns about it?
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This could be a good read on evidential deep learning
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Dear Research Gate Members,
It has been observed worldwide that the individual with weak immune system can be easily attacked by Novel Corona Virus (COVID-19). The prominent health experts are also suggesting to improve immune system against Novel Corona Virus (COVID-19).
Please, share your expert suggestions on the following question.
How can we strengthen our immune system to fight against Novel Corona Virus (COVID-19) spread?
Thanks & Regards
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In recent years, ecological innovations have also been created on the basis of other non-ecology science. Ecological innovations are mainly created, among others, in the field of renewable energy sources, improvement of waste segregation techniques, recycling, treatment of polluted water, reclamation of a devastated natural environment, energy-efficient construction, electromobility etc. However, more and more eco-innovations, new technological solutions, technical improvements that fit in sustainable pro-ecological economic development also arises in many other fields of science.
In view of the above, are examples of pro-ecological undertakings, technological improvements compatible with sustainable ecological development or ecological innovations that are also created in one of the following or other related fields of science, for example: Molecular Biology, Biotechnology, Anthropology Theory, Medicine, Electrical Engineering , Artificial Intelligence, Genetics, Business Administration, Risk Management, Big Data, Business Intelligence, Automation & Robotics, Climatology, Agriculture, Biophysics, Biochemistry, Medical Intelligence, Artificial Neural Networks, Ecosystem Analysis, Power Engineering, Construction, Food production, Forest ecology, Biology, Geoscience, Government Programs, Behavioral Sciences, Biodiversity Assessment, Green Architecture, Greenhouse, Waste, Household Products, Information Society, Innovation Management, International Entrepreneurship, Internet Technologies, Knowledge Creation, Bioelectric Energy gy Sources, Business Model Innovation, Cataclysmic Variables, Chromatography, Clean Energy, Cleantech, Climate Prediction, Collaborative Innovation, Commercialization, Computational Intelligence, Computer Science and Engineering, Conservation Biology, Consumer Behavior, Corporate Governance, Creative Economy, Crisis Communication, Cyber ​​Security, Data Analysis, Database Administration, Development Cooperation, Digital Ecosystems, Discovery, Earth Sciences, Earthquake Forecasting and Geocataclysm, Econometric Analysis, Economic Integration, Economics of Innovation, Ecosystem Engineering, Electricity, Electronic Systems, Energetic Materials, Energy Technologies, Environment, Environmental Biodegradation, Flora, Food Consumption Life Sciences, Logistics Management, Materials for Sustainable Energy, Astronomy & Astrophysics, Nanomaterials, New Media Technology, Recycling, Physics of Global Warming, Plant Protection, Predictive Analytics, Production Planning, Project Development, Public Eco nomics, Public Policy, Public Policy, Sociobiology, Space Science, Sustainable Agriculture, Sustainable Development Strategies, Technology Forecasting, Transport Economics, Water Resources, Weather Forecasting, Wildlife Conservation, World Economy, ...?
In view of the above, the current question is: Will ecological innovations be created in the 21st century on the basis of other sciences besides ecology?
Please, answer, comments. I invite you to the discussion.
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I doubt this because environmental legislation is facing difficulty in implementation by investment holders in the world.
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I am starting a systemic review. And it's my first one. I have figured out the PICO and search keywords. I am overwhelming with massive results from different search engine. They contains duplicates. What is the best practice to combine all the result and remove duplicates.
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Agree with Rabia Bashir
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Blockchain-as-a-Service(BaaS) in the fields of medicine, economics or other fields?
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I understand vaguely that the first author is supposed to be the one who "did the most work", but what counts as "work" in this comparison? Does "most" mean "more than all the other coauthors together" or just "more than any other coauthor"? What happens when the comparison is unclear? How often is "did the most work" the actual truth, versus a cover story for a more complex political decision?
I realize that the precise answer is different for every paper. I'm looking for general guidelines for how an outsider (like me) should interpret first authorship in your field. Pointers to guidelines from journals or professional societies would be especially helpful.
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Good journals accept submission with clear authors contributions to submitted work. First author is considered the main figure for the research item
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If the ambient temperature is very cold, below -15 degree celcius it's difficult to handle medicine for veterinarians specially in field conditions.
What are the best way to prevent freezing of medicine (in a vial) in lower temperature?
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Apply material around the medicine container or may adding substance that have a low freezing degree and should not affect the medicine itself.
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The coronavirus pandemic has brought the world to a grinding halt and no doubt has altered the lives of each one of us. I think COVID-19 also has an impact on our normal research (i.e. related to our relevant field) and diverted us to work on various aspects of coronavirus to help combat the virus.
What's your opinion in this regard?
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I agree. My routine research into the environmental epidemiology of waterborne disease, and my preferred research into alcohol policy and climate policy, have been largely pushed aside in favour of research into the geospatial epidemiology of covid-19.
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I am looking forward to designing a Printed Electronics circuit for Pill Reminder/ Medicine Reminder. The circuit is printed on the back of the medicine stip.
I found some interesting circuit which based on IoT, Arduino to get a reminder at a particular set of time. IT cannot possible to fix the smallest microcontroller kit (i.e. ATTO) into medicine stip. I want to make a basic circuit with passive electronics components. Another idea is to design a circuit for a wire-break alarm or reminder with sufficient delay. The IC 555 dose-not possess longer delay and multiple wire-break alarm system.
If you have any ideas please share.
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You can use microcontroller in small sot23-6 package (like as PIC10F200) and flexible PCB, but main problem is power. Battery is big and cannot be placed on flexible PCB.
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Hello,
I would appreciate it if you could suggest me studies based on natural language processing (NLP) to help assisting medical emergency cases.
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I have been working in the field of domain specific artificial intelligence and domain specific synthetic languages for several years. This is a very important question. I discussed this subject with a colleague just yesterday. A few notes from our discussion follows.
There are some jobs where a person’s eyes and hands must be free to perform their work, yet they must be able to communicate with other people and computer systems that help them perform that work. In some of these jobs, safety is most important.
Although systems like Alexa and Siri are already in wide use, they do not today provide the degree of reliability and safety that would be required for use in an emergency room or neonatal ICU.
In such cases, it would be prudent to a create a task specific synthetic language designed for communication between humans and computer systems while humans perform their work, and computers answers questions, provide information, control task specific equipment, and other functions, thereby enabling a person to perform their work with their hands and eyes free to focus on the task at hand.
In short summary this would require implementation of computer systems that are able to:
· reliably hear and process spoken words
· translate spoken words into human and machine-readable form (text)
· verify that the spoken words, in human and machine-readable, form comply with the specification (grammar) of the synthetic language
· determine what question or command has been voiced by the human,
· invoke the procedure that will answer the question, provide requested information, or perform the command using task specific equipment.
· reply in some audible or visible form if the spoken words were not recognized or if the spoken words in human and machine-readable form do not comply with the specification of the synthetic language, or if they are used in the wrong context.
For added safety, before such capability is put into use, it would be necessary to generate many requests and commands both correct and incorrect in their formation to verify that both correct and incorrect commands can be successfully categorized as such.
For added safety, before such capability is put into use, it would be necessary to generate many requests and commands and to verify that the correct procedures are invoked, and through simulation, verify that the procedures safely perform the intended action.
Simply stated, a synthetic language is a set of words and set of rules for how to create requests or commands using the words of that language that can be spoken by a human, recognized by a computer, properly interpreted by a computer, and safely translated into the intended actions.
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I'm looking for an excel sheet to calculate the STS Score. From the website http://riskcalc.sts.org/stswebriskcalc/calculate. Does anyone have a worksheet to calculate the STS Score?
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I also tried to find the Excel version of STS calculator, but I still didn’t find it. There are more than 60 parameters & it’s convenient to use it on STS site.
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Hello,
My research work focuses on the use of NLP and voice recognition for the medical emergency assistance.
So I would appreciate it if you suggest me some contributions that could be done in this area.
Best regards,
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Dear Artem Kramov , thank you so much for your valuable reply, I'll take your suggestions into consideration.
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Differences between Telemedicine and conventional medicine? Which is better?
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Pros and Cons of Telemedicine for Today's Workers
  • Convenience. ...
  • Less time in the waiting room. ...
  • Cost-efficiency. ...
  • Expedited transmission of MRIs or X-rays for a second opinion. ...
  • Privacy assurance. ...
  • Electronic glitches. ...
  • Physician resistance. ...
  • Inadequate assessmen
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Hello,
I am seeking recommendations from the Research Gate community regarding studies about
the IT and Artificial intelligence solutions to assisting medical emergency cases.
What are the perspectives and future works that could be done in this area?
Best regards,
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With the appearance of COVID-19 vaccines on the market, many available choices are there.
Which one is good?
Which one is safest?
Which one is most expensive?
Which one is easiest to store?
How many doses are required?
Other than intramuscular injection, any other forms?
How to check immune response after?
Do we need post-injection blood test?
Do we need annual booster dose?
Do we need new vaccines every year by prediction as if flu vaccines?
Any contraindications?
Any allergy from vaccination?
Do we need to mask after injection?
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Agreed with dear Arvind Singh
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In the structure of many drugs, there is a carboxylic group
What is the significance of this group? Why should it exist in the structure of a drug?
Do you know any article or book or reference about this subject?
Thanks a lot
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In all metabolic processes in nature, electron transfer takes place at the molecular level. Two fundamental atoms in all living entities are oxygen (O) and nitrogen (N). In direct combination, they form NO, which is one of the most crucial biomolecules because it has a free electron ("free radical"). It is part of a universal communication system in biologicals cells.
If we go one level of abstraction higher, we find the amino (NH2) and the carboxyl (COOH) groups. In the carboxyl function, the electrons can migrate from one O to the other via the C atom (mesomerism). Thus, the H atom can easily migrate to the "partner" NH2 - the electrons are "free" and can participate in biological processes.
It is also why phenols, especially polyphenols (green tea EGCG, resveratrol, quercetin), are biologically very active. If both functional groups occur within one molecule, we have one of nature's most essential building blocks, amino acids.
With more atoms and larger molecules, the electron transfer becomes more complicated, but it can explain almost any drug's mechanism of action. It is perhaps interesting to note that electron transfer within biomolecules is sometimes completely different from what we know from the chemical laboratory.
That is why "free radicals" in the body are not generally harmful but vital.
SUMMARY
In summary, it is one of the most important functional groups in nature. That is the reason why it occurs as a functional group in so many drugs.
Attached you will find a link to a paper describing the effect of some functional groups in drugs.
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The general public must be made aware of the mode of transmission, presenting symptoms and the measures that can be undertaken to prevent the spread of infection.
Few options- Media, Webinars...
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Awareness can be increased if everyone is involved, the task of making people aware of COVID-19 prevention should not be left to the government alone. Let all stake holders be involved: that is civic leaders, the church, the education bodies, traditional leaders NGOs and the others.
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Bacteriophages very effective against infections.
Many of them such as anti-Staphylococcus or anti-Streptococcal widely used in practical medicine.
Some bacteriophages can be oncolytic and effective against cancers.
How Bacteriophages recognize and lyse cancer cells? Mechanism of action ?
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As I know, these mechanisms are poorly studied for today. But it is well-known that some bacterial species/strains have surface antigene similarity with many of the human and animal tumors. On this fact, one kind of the anticancer vaccines production is based. If you want to obtain a more detailed consultation and the recent references in this field, try to connect with Dr. Gennady Didenko or Dr. Irena Voyeykova in the R.E.Kavetsky institute of experimental pathology, oncology and radiobiology, NAS of Ukraine.
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There is a continuing accusation by alternative medicine practitioners that their method cannot be proven or their proof is inadequate. The basic principles, diagnostic, nomenclature and medical methods of Western and alternative (eastern) medicine are different. The western is linear and reductive, the eastern is more network-oriented. These require different methods of statistical analysis. Can they be judged by an approach?
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The scientific method can be successfully applied to natural pharmacy !
I do not see a methodological problem, but an economic one.
Profiteering-from-disease is the standard formula, for the moment, and this 'naturally' implies a bias for certain medical methods, e.g. surgery, drugs.
An 'ill' medical system produces also 'healthy' winners.
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