Questions related to Medicine
Reality may increasingly hurt – #Genomic #targetedtherapy
Changes between 2006 and 2020
-eligibility from 5.13% to 13.60% *only*
-response from 2.73% to 7.04% *only*
The authors use in their discussion different paraphrasing: “the percentage of eligibility for and response to genome-targeted drugs increased 54% and 28%, respectively”
which from the objective point of view is correct, but this implies a major improvement, although the reality of inefficiency is different
Some may state *the house of cards collapse of the breakthrough* ?
Otherwise today's basics of biotechnological power politics in created hypes of landmarks, breakthroughs, which might be seen in the accordance of the Latin epic poem, The Aeneid by Virgil:
‘parcere subiectis, et debellare superbos’ (I believe it at any rate)
Article Haslam et al. (2021) Ann Oncol 2021, DOI 10.1016/j.annonc.2021.04.003
The Aenedid from Virgil Vergil (19 BC), Aeneis, Liber sextus, Vers 847-853.
#medicine #health #medicalsciences #breakthroughs #landmarks #hallmark #hype #criticalthinking
Under COVID-19, healthcare facilities requests a lot of sterilization to prevent hospital transmission of the disease. Bleach solution and many other disinfection agents may not be effective against such a large scale of usage.
Can ultraviolet light be used to inactivate the virus?
Can it be applied on whole room disinfection?
Can it be used on high turnover medical equipment sterilization? E.g. stethoscope.
Can it be used to inactivate infected donors' blood products or body fluids?
It's 99 days since the first case of COVID-19 in Hong Kong, and we are welcoming the 5th days of 0 new cases of COVID-19 following a week of <10 cases per day.
How should we define the end of a local endemic?
How long should the latent period be defined?
When is it safe to resume social activities?
Should territory wide screening of asymptomatic people be done before declaring the end of endemic?
We are compiling comprehensive details for traditional medicines and their marketing approval in a particular country. For now, we are reviewing Kampo Medicines of Japan. But somehow we are not able to get suitable guideline documents (original from Japanese Regulatory Agency's Website). Can anyone guide us? From where we can find guidelines for marketing approval of Kampo medicine in Japan?
How can you decide the judgment on a specific article whether it is good or not, is your judgment depends on the title of the article or the abstract or the publishing journal or something else?
Please, share us your opinions about the discussion
COVID-19 is mainly a respiratory disease that affects the lung, although other organ structures with endothelium seems to be affected too.
When should we do imaging?
What is the aim of the imaging?
How can it help with management?
Do you agree with the following consensus statement?
How will you adjust your own practice and difficulties encountered? Why?
The Role of Chest Imaging in Patient Management during the COVID-19 Pandemic: A Multinational Consensus Statement from the Fleischner Society. Chest. 2020 Apr 07.
I have watched a child crying loudly in pain, while collecting blood for testing. Can we develop a technique which can collect the blood or inject a medicine to children in a complete pain-free way ?
Iam a dental student and i want to increase my knowledge in writing drug chart to patient in the future, can you give me some advises to increase my knowledge in this field, i the name of drug and the number of dose is very consued and i forgot it fast so how the doctors write it easy...... So can you advise me to be good in the future
Hello, I will try to produce Sb2S3 films with thermal evaporation technique using Sb2S3 pellets or Sb pieces. Then I will complete the production with thermal annealing. Could you please give information about the risks of Sb2S3 pellets or Sb pieces and the precautions I should take?
Deep Reinforcement Learning Training course
Time: January 15-January 18
DeepLearning Training course
Time: January 27-January 30
(Report for three days on the first day; Deploy the computer test in advance)
III. Lecture 1:
Course 1. Introduction to Intensive Learning
Course 2. Strengthen the foundation of learning
Course 3. Deeply strengthen the foundation of learning
Course 4, Multi-agent Deep Intensive Learning
Course 5. Multi-task deep intensive learning
Course 6. Strengthen learning and application
Course 7. Simulation Experiment
Course 8. Supplementary courses
IV. Lecture 2:
Lesson 1: Tensorflow Beginners to Proficiency:
Lesson 2: Image Classification:
Lesson 3: Object Detection:
Lesson 4: Face Recognition:
Lesson 5: Algorithm Implementation:
1. Convolutional neural network CNN
2. Circulating neural network RNN
3. Strengthen learning DRL
4. Antagonistic generation network GAN
5. Transfer learning TL
6. Specific examples of practical medicine, remote sensing images, oil exploration and intelligent transportation
Contact person: Li Luxin (teacher)
Mobile phone: 13311241619
QQ: 1942892948 (same as WeChat)
Strengthen learning QQ exchange group number: 872395038 (add group remarks: Li Luxin invited)
Deep learning-distance online course QQ group number: 1057802989 (plus group remarks: Li Luxin invited)
Under the pandemic of COVID-19, screening becomes important to tackle the spread. Fever is one of the screening criteria for many public places screening for access.
However, how is fever defined?
Is the 0.1 degree change makes the significance?
What is the range of standard deviation being acceptable?
What machine is accurate?
Is those hand held infrared measuring machines reliable?
Is there scenarios giving false negative tha may make a huge consequence?
Normal Body Temperature: A Systematic Review.
Open Forum Infect Dis. 2019;6(4):ofz032. Published 2019 Apr 9.
I know that an infant's brain can repair itself when damaged but why doesn't the same happen in adults after stroke or brain injuries?
Dear seniors and researchers,
Briefly introducing myself, I am a fourth year medical student from Indonesia. Currently, I am performing a multiple logistic regression on several possible factors affecting medical student preference toward distance learning in this pandemic era. Honestly, it is my first time in using logistic regression in my work, and I might encounter several confusing issues regarding this statistical procedure. I have selected 14 eligible covariates for multiple logistic regression according to its significant p-value (0.000) during their simple logistic regression. After including all of those 14 covariates to the model, the ExpB (odds ratio) of all 14 covariates become insignificant despite decent model (Good result of Omnibus test, R-squared, and Holmer and Lemeshow test). All of statistical procedure were performed in SPSS ver 22.
Regarding this issue, what should I do in responding those finding? Is it correct to interpret that there were no significant relationship between all of 14 covariates and dependent variable (student preference toward distance learning) simultaneously? Or is there any suggestion of appropriate technical steps in conducting multiple regression analysis?
With the developing stories of the spread of COVID-19 all around the world, which has been declared as a pandemic by WHO recently, I am wondering, in how much time this virus would vanish from the surface of the Earth? Is there any scientific study available for this?
Please share your opinions.
The development of a vaccine for COVID-19 has become a battleground for many countries to prove to the world/their own peoples that their technology is superior and better than the competitors at the international stage. it is always a point of concern when science is serving the political establishment. Russia claimed that they have developed 'the first' Covid-19 vaccine. WHO is raising concern about the validity of this claim and urging Russia to provide sufficient data to back this claim.
Is it possible for the same scenario to be repeated in the US? An election is near and COVID-19 vaccine development can influence the result.
This might be considered a worst case scenario.
Repeated strikes by such a virus would scythe defenseless new victims each time, leaving fewer and fewer survivors.
For the species to survive, humanity would have to evolve resistance or other means of survival.
Is such a virus possible?
How would its epidemic spread be modeled?
Has a virus like that occurred in the past?
How would we deal with such a virus in the future?
What strategies would defeat such a virus?
As we know MSG is widely used food additive and acts as a flavour enhancer. It is also approved by USFDA as GRAS! But some controversy are there regarding clinical reports where the physiological illness was shown after consuming MSG. So, is MSG good or bad for health? Are there any research related conclusions?
Thanks & Regards
I hope you are all doing well. I have a question to all of you. I love to teach and so far I have been teaching everything from international business, marketing, management to organisational psychology. I feel ambivalent towards this however.I love to teach and Im curious in my nature and what better way to learn new things than to teach? However I also feel that if I continue being a generalist It might also be bad since I risk loosing touch with my main specialisation.
What are your thoughts? Your experiences?
My speciality is this :
Best wishes Henrik and professor Hugo 3 months old who keeps me company when Im trying to work :-)
Ps stay safe.
Although the interests that exist around health and PE have a good sense and meaning, they may not be as benign as, ironically, they think they are. So, what are the risks of Medicine dictating the aims of Physical Education?
Is there a complete tutorial for using EHR (Electronic Health Record)?
I mean extracting some data like how many people have specific symptoms?
I had a few students help me with a simple but time-consuming task. The data they helped with will be used in a scientific paper. The students are part of the Student Research Program (SRP) at my institution and they received a class credit for their work with me. Should I include these students as co-authors on the manuscript?
I also had a student volunteer help me on the same research project. The student did not get a class credit for their help. Should the student be a co-author on the paper?
Thank you in advance for your opinions/suggestions.
I found a reference to this distinction on pub med that dates to the 70s. Efficacy is how well a treatment or intervention works in ideal circumstances. Effectiveness is how well a treatment or intervention works in normal practice. Although there are many references to this distinction and discussions of why it occurs, nobody seem to mention the origins of this distinction. Furthermore, this distinction seems more accepted in general medicine than in behavioral health.
Ayurveda, TM of India, advises to avoid Curd intake in diseases that have Kapha dosha predominance like Diabetes, Respiratory problems; in diseases arising out of Raktha dusti (Blood tissue vitiation) like Skin diseases and also in conditions where the digestive fire (Agni) is weak like during Night time. Regarding this Curd advisory, Ayurveda has very clear fundamental concepts and the findings of which have also been noticed in clinical practice as well.
Here I want to know are there any other Traditional system of medicine which has similar or any other observation about Curd intake?
I read that diabetic retinopathy can affect people with type 1 and 2 diabetes, especially those who have uncontrolled blood sugar and have diabetes for a long time. How can uncontrolled blood sugar cause diabetic retinopathy? and how is the treatment for diabetic retinopathy patients? thank you.
Is it completely dependent on the region that patient lives in? If so, I'm specifically interested in the Southern California (United States) region.
It would be great if we get information regarding this from all around the world. Like we have Ashwagandha (Withania somnifera) in Ayurveda, Indian system of Medicine.
RNA vaccines follow a different strategy, without using any "real" component of the virus at all. Instead, researchers aim to trick the human body into producing a specific virus component on its own. Since only this specific component is built, no complete virus can assemble itself. Nevertheless, the immune system learns to recognize the non-human components and trigger a defense reaction. So May I ask, What are your opinions about the safety and efficacy of the BNT162b2 mRNA Covid-19 Vaccine?
In connection with the development of technology, the current technological revolution, which Industry 4.0 information processing technologies find application in the development of medicine?
i'am searching for some good reviews in the field of hydrogen use, hydrogen effect, hydrogen fuel technology in the field of sports and medicine.
please share your papers with me.
is there some research in the field of regeneration in sports and post operation in medicine?
is there some research in special sports like triathlon, canoe, swimming and lifting?
Hello and regards, our study investigates the relationship between latent toxoplasmosis and psychiatric and psychological mental disorders. It is part of my research (Ashkan Latifi, postgraduate student of psychology at University of Tehran- Iran) in partial fulfilment of the requirements of my master’s degree. By filling in this questionnaire, you have been of great help to me and to those with toxoplasmosis. In addition, by optionally sharing your email with me, you allow me to inform you of any possible toxoplasmosis-associated psychological/psychiatric problems in you under the supervision of two professors of University of Tehran (Dr. Abbas Rahiminezhad, psychologist and Dr. Reza Rostami, psychiatrist) for free. You can participate in this study if you have latent toxoplasmosis (other than congenital toxoplasmosis) and are at least 18 years old. The approximate response time to the questionnaire is ten to fifteen minutes. Thank you in advance for your participation in this research.
Link to the questionnaire: https://docs.google.com/forms/d/1Qvu3J0MuXz56r1d1dZtpWBYHKUmXDByx_3eQ37LRsg0/viewform?edit_requested=true
Articles that share the history and development of medicine in the UK, any aspect of medicine and medical education.
The triangular theory of love by Sternberg, characterises love in an interpersonal relationship using three different dimensions: intimacy, passion, and commitment.According to this theory different stages and types of love can be categorised by different combinations of these three elements. My question is this: does this model fully capture the essense of what we call love. Can love not also have other attributes, we can have feelings of love towards a person without having either commitment, passion or intimacy, some people are asexual for example and lack commitment, others such as teenagers lack the understanding of what love is. Do you agree with this theory or do you like me see problems associated with such a sharp division of element of human affects. Best wishes Henrik
The extensive successful use in people of mRNA vaccines for Covid-19 suggests they mark a key scientific breakthrough with broad impacts. These breakthrough vaccines are notable for combining two advances examined for years in the laboratory: pseudouridine modified mRNA and its encapsulation in lipid nanoparticles. Pseudouridine has been used in nucleotides for years to stabilize and study key protein-nucleotide complexes (e.g. Parikh et al. Proc Natl Acad Sci U S A. 2000 May 9;97(10):5083-8. doi: 10.1073/pnas.97.10.5083. PMCID: PMC25785 ). In fact, Pseudouridine (Ψ) is the most abundant RNA modification and has been termed the 5th base of RNA (Front. Cell Dev. Biol., 16 March 2021 https://doi.org/10.3389/fcell.2021.628415). Similarly Lipid nanoparticles have been used and studied for over 20 years (e.g. Puri et al. Crit Rev Ther Drug Carrier Syst. 2009; 26(6): 523–580. PMCID: PMC2885142). Yet the combination of mRNA modification by N1-methylpseudouridine to increase safety and efficacy with lipid nanoparticles to encapsulate mRNA for its protection and delivery made the Covid-19 mRNA vaccines feasible. Importantly, this transformative combination seems applicable to other vaccines and approaches suggesting it is worth considering the many possible applications that may advance biotechnology and human health.
Do you have medical cooperatives in your country? What is your opinion about the possible models of cooperatives in medicine that are proposed in this article? -
Students pursuing medicine are constantly exposed to the risk of mental exhaustion and the sequalae that follows, which affects their mental health adversely. What would you as an instructor do to make sure our students don't fall prey to mental illness?
Patented medicines are expensive making it difficult for the lower or middle class families to afford it. If a certain medicine is helpful to the society, what can the government do to regulate the market, so that the socio-economic surplus is as large as possible while not taking away the company's patented rights.
The field of life-science and mathematics are always intermixing with each other, however, the COVID-19 has brought them more closely than before. Many researchers have developed fractional differential equations in life sciences. For example anomalous diffusion in cell membranes, epidemiological models, etc. I am particularly interested to know if there are applications of fractional differential equations in medicine?
It may be in your education and experience that you deal with the structure of organic medicines. Which combination do you think is most common in organic medicine?
For example, many drugs have carboxylic acid in their structure. In your opinion, which compounds play an important role in the structure of the largest number of drugs?
AI showed its promise in many fields, but most of researches in AI application on medicine is still "proof-of concept". So how do clinicians feel about AI? What are clincians' concerns about it?
Dear Research Gate Members,
It has been observed worldwide that the individual with weak immune system can be easily attacked by Novel Corona Virus (COVID-19). The prominent health experts are also suggesting to improve immune system against Novel Corona Virus (COVID-19).
Please, share your expert suggestions on the following question.
How can we strengthen our immune system to fight against Novel Corona Virus (COVID-19) spread?
Thanks & Regards
To all who currently work in healthcare,
Please complete the questionnaire "COVID Vaccine Hesitancy in healthcare workers" developed by the Infectious Diseases-International Research Initiative (ID-IRI). It will only take you 5 minutes!
This study aims to identify the factors influencing the willingness to accept or refuse the COVID-19 vaccine. The survey is available in several languages.
Thanks in advance for your time and collaboration.
In French: https://docs.google.com/forms/d/e/1FAIpQLScmw0Hv2YsHswUXL6Eq3rPjeS0Oq7NhWmXhlndNbk_HUeMV0Q/viewform?usp=sf_link
In Russian: https://docs.google.com/forms/d/e/1FAIpQLSeiucT7xguRjJpGq38Zgo14BZHzUCKH24S53_D2bdGFpCblbg/viewform?usp=sf_link
In Serbian: https://docs.google.com/forms/d/e/1FAIpQLSfFexuR547yau0JA1m76wLkHW0l1D81AgR07KxNIr40_BuoYw/viewform?usp=sf_link
In recent years, ecological innovations have also been created on the basis of other non-ecology science. Ecological innovations are mainly created, among others, in the field of renewable energy sources, improvement of waste segregation techniques, recycling, treatment of polluted water, reclamation of a devastated natural environment, energy-efficient construction, electromobility etc. However, more and more eco-innovations, new technological solutions, technical improvements that fit in sustainable pro-ecological economic development also arises in many other fields of science.
In view of the above, are examples of pro-ecological undertakings, technological improvements compatible with sustainable ecological development or ecological innovations that are also created in one of the following or other related fields of science, for example: Molecular Biology, Biotechnology, Anthropology Theory, Medicine, Electrical Engineering , Artificial Intelligence, Genetics, Business Administration, Risk Management, Big Data, Business Intelligence, Automation & Robotics, Climatology, Agriculture, Biophysics, Biochemistry, Medical Intelligence, Artificial Neural Networks, Ecosystem Analysis, Power Engineering, Construction, Food production, Forest ecology, Biology, Geoscience, Government Programs, Behavioral Sciences, Biodiversity Assessment, Green Architecture, Greenhouse, Waste, Household Products, Information Society, Innovation Management, International Entrepreneurship, Internet Technologies, Knowledge Creation, Bioelectric Energy gy Sources, Business Model Innovation, Cataclysmic Variables, Chromatography, Clean Energy, Cleantech, Climate Prediction, Collaborative Innovation, Commercialization, Computational Intelligence, Computer Science and Engineering, Conservation Biology, Consumer Behavior, Corporate Governance, Creative Economy, Crisis Communication, Cyber Security, Data Analysis, Database Administration, Development Cooperation, Digital Ecosystems, Discovery, Earth Sciences, Earthquake Forecasting and Geocataclysm, Econometric Analysis, Economic Integration, Economics of Innovation, Ecosystem Engineering, Electricity, Electronic Systems, Energetic Materials, Energy Technologies, Environment, Environmental Biodegradation, Flora, Food Consumption Life Sciences, Logistics Management, Materials for Sustainable Energy, Astronomy & Astrophysics, Nanomaterials, New Media Technology, Recycling, Physics of Global Warming, Plant Protection, Predictive Analytics, Production Planning, Project Development, Public Eco nomics, Public Policy, Public Policy, Sociobiology, Space Science, Sustainable Agriculture, Sustainable Development Strategies, Technology Forecasting, Transport Economics, Water Resources, Weather Forecasting, Wildlife Conservation, World Economy, ...?
In view of the above, the current question is: Will ecological innovations be created in the 21st century on the basis of other sciences besides ecology?
Please, answer, comments. I invite you to the discussion.
I am starting a systemic review. And it's my first one. I have figured out the PICO and search keywords. I am overwhelming with massive results from different search engine. They contains duplicates. What is the best practice to combine all the result and remove duplicates.
I understand vaguely that the first author is supposed to be the one who "did the most work", but what counts as "work" in this comparison? Does "most" mean "more than all the other coauthors together" or just "more than any other coauthor"? What happens when the comparison is unclear? How often is "did the most work" the actual truth, versus a cover story for a more complex political decision?
I realize that the precise answer is different for every paper. I'm looking for general guidelines for how an outsider (like me) should interpret first authorship in your field. Pointers to guidelines from journals or professional societies would be especially helpful.
If the ambient temperature is very cold, below -15 degree celcius it's difficult to handle medicine for veterinarians specially in field conditions.
What are the best way to prevent freezing of medicine (in a vial) in lower temperature?
The coronavirus pandemic has brought the world to a grinding halt and no doubt has altered the lives of each one of us. I think COVID-19 also has an impact on our normal research (i.e. related to our relevant field) and diverted us to work on various aspects of coronavirus to help combat the virus.
What's your opinion in this regard?
I am looking forward to designing a Printed Electronics circuit for Pill Reminder/ Medicine Reminder. The circuit is printed on the back of the medicine stip.
I found some interesting circuit which based on IoT, Arduino to get a reminder at a particular set of time. IT cannot possible to fix the smallest microcontroller kit (i.e. ATTO) into medicine stip. I want to make a basic circuit with passive electronics components. Another idea is to design a circuit for a wire-break alarm or reminder with sufficient delay. The IC 555 dose-not possess longer delay and multiple wire-break alarm system.
If you have any ideas please share.
I would appreciate it if you could suggest me studies based on natural language processing (NLP) to help assisting medical emergency cases.
My research work focuses on the use of NLP and voice recognition for the medical emergency assistance.
So I would appreciate it if you suggest me some contributions that could be done in this area.
I am seeking recommendations from the Research Gate community regarding studies about
the IT and Artificial intelligence solutions to assisting medical emergency cases.
What are the perspectives and future works that could be done in this area?
With the appearance of COVID-19 vaccines on the market, many available choices are there.
Which one is good?
Which one is safest?
Which one is most expensive?
Which one is easiest to store?
How many doses are required?
Other than intramuscular injection, any other forms?
How to check immune response after?
Do we need post-injection blood test?
Do we need annual booster dose?
Do we need new vaccines every year by prediction as if flu vaccines?
Any allergy from vaccination?
Do we need to mask after injection?
In the structure of many drugs, there is a carboxylic group
What is the significance of this group? Why should it exist in the structure of a drug?
Do you know any article or book or reference about this subject?
Thanks a lot
The general public must be made aware of the mode of transmission, presenting symptoms and the measures that can be undertaken to prevent the spread of infection.
Few options- Media, Webinars...
Bacteriophages very effective against infections.
Many of them such as anti-Staphylococcus or anti-Streptococcal widely used in practical medicine.
Some bacteriophages can be oncolytic and effective against cancers.
How Bacteriophages recognize and lyse cancer cells? Mechanism of action ?
There is a continuing accusation by alternative medicine practitioners that their method cannot be proven or their proof is inadequate. The basic principles, diagnostic, nomenclature and medical methods of Western and alternative (eastern) medicine are different. The western is linear and reductive, the eastern is more network-oriented. These require different methods of statistical analysis. Can they be judged by an approach?
It is known that scientific knowledge is replicated each time at more unusual speeds, however, humanity expects more from our scientific work, that is, solutions to problems that have accumulated and that it is necessary to solve to improve the quality of life . It would be good to reflect on those expectations.
May the New Year bring you happiness, peace, and prosperity.
Wishing you a joyous 2021
What are your wishes for the new year 2021?
What is the better option to improve immunity ? Medicine or diet ?
As per Ayurveda, Oja is the Bala (~immunity) which is originated by the Ahara which further nourishes Rasa, Rakta etc Dhatu and Finally it converted in Oja.
Do you know of any applications that help adjust references in a manuscript to a journal's stylesheet? I am familiar with Mendeley but I was wondering whether there is program that does not require prior uploading cited papers (just as Mendeley does).
Thanks a lot!
Could we call published papers from all disciplines as SCIENTIFIC PAPER or just we say it for physics, biology, chemistry, mathematics, engineering, medicine or related things whereas linguistics or i.e. history is same?
Vertigo is a condition that can make it feel like you or your surroundings are spinning, sometimes leading to a loss of balance, according to the U.S. National Library of Medicine.
Coronavirus 2019 or COVID-19 is a novel entity which had led to many challenges among physicians due to its rapidly evolving nature. Vertigo or dizziness has recently been described as a clinical manifestation of COVID-19.
So, Are dizziness and vertigo COVID-19 Symptoms? and why?
This discussion section is about to Explore the issues that medical providers - doctors - nurses face during their battle, share your experience on covid unit,
In addition which factors facilitated in supporting you(mentaly and physically)?
How good does the developed protocols and plans of preparedness work on your facility?
Thank you for your time!
I am looking forward to your replies
I am a high school student writing a medical innovation project for a competition. My project involves TALENs gene knockdown and delivering it to the brain via the high-capacity adenoviral vector (HCAdV). The project will be in vivo (mouse models).
I need to write my procedure so I want to understand how TALENs can be packaged in the viral vector. From what I know, plasmids are transfected into cells and they produce the proteins that construct the components of the viral vector. I would greatly appreciate an explanation of how this process works, how TALENs can be packaged in the vector, and any other tips that you might have for my project.
As a researcher, you may be frustrated in finding continuous funding for sustaining your research. However, would there be any conflict of interest to be a researcher as well as a fund raiser simultaneously at the same time?
What regulations are there to limit the grey area?
Which authorities were looking on such issue?
What if the fund raising is for charity organizations in the field (particularly pediatrics and rare diseases) and is unrelated to the researcher's work?
In medicine field, the practice of physicians fundraising from their own patients raises three main concerns:
(1) undue pressure on patients to contribute,
(2) possible expectations of preferential treatment from donors, and
(3) concerns about patient confidentiality and trust.
What do you think?