Science topic

Medical Image Registration - Science topic

Explore the latest questions and answers in Medical Image Registration, and find Medical Image Registration experts.
Questions related to Medical Image Registration
  • asked a question related to Medical Image Registration
Question
2 answers
Hello, I am currently experimenting on medical image registration and I would like to do a baseline registration between a CT and an MRI scan of the liver of a patient for selective internal radiation therapy dosimetry. I would like to know if there is any data available online that I could use.
Relevant answer
Answer
The public dataset closest to your objective is I think https://chaos.grand-challenge.org/Combined_Healthy_Abdominal_Organ_Segmentation/
You may need to register modalities though.
  • asked a question related to Medical Image Registration
Question
4 answers
is there any publicly available dataset for conventional coronary angiography images?
Relevant answer
Answer
James O'Callaghan there doesn't seem to be anything...
  • asked a question related to Medical Image Registration
Question
1 answer
Hi,
Is there any longitudinal datasets (CTscan or MRI, 2D or 3D) of tumors publicly available ? I'm doing a project where I to apply deep learning to see the evolution of lesions/tumors over time for the same patient and I'm struggling to find relevant datasets.
  • asked a question related to Medical Image Registration
Question
6 answers
During preprocessing medical image data different techniques should be considered such as cropping, filtering, masking, augmentation. My query is, which techniques are frequently applied to medical image datasets during pre-processing?
Relevant answer
Answer
Image Pre-Processing Techniques are classified into four kinds, which are given below.
1. Brightness transformations/corrections for pixels
2. Geometric Transformations
3. Image Filtering and Segmentation are the third and final steps.
4. Fourier transform and image restoration are examples of Fourier transform and image restoration.
Kind Regards
Qamar Ul Islam
  • asked a question related to Medical Image Registration
Question
4 answers
I am a Master student in Biomedical (Bio-electrical) Engineering and work on " 2D-3D registration ( CT and X-Ray) as my thesis.
I created DRR from CT and want use CNN( Convolutional Neural Network)for estimate and train 6 transformation parameters of registration between DRR and X-Ray images.
I would be grateful if you could give me some information or code in MATLAB.
Thank you for your time.
Relevant answer
Answer
Please note that you
can program it.
Use my example in MATLAB
in my paper
An Adaptive Filter to Pick up a Wiener Filter from the Error using MSE with and Without Noise
  • asked a question related to Medical Image Registration
Question
2 answers
Hi, I have some DTI data and I want to use ANTs to make a b0 group wise template to normalize my data to the IIT_mean_b0 image. I want to use buildtemplateparallel.sh and SyN algorithm ,but I'm the amateur one. How am I supposed to run this and what are the inputs?
Relevant answer
Answer
Joan Jiménez-Balado Thank you Joan
  • asked a question related to Medical Image Registration
Question
13 answers
Now I'm using python to do some image registration,but I found there is no useful tool for me.So I have to do some basic jobs and implement some basic algorithms by myself.It is so slowly and a little bit difficult.I wonder there are some useful toolkit to help me do image registration in python.Curiously I want to know which language the researcher use to do the image registration.Matlab? or others?
I just finished a program about Maximization Mutual Information in registration using python,but it seems very slowly,and a little bit wrong.
If you knew how to do image registration,including what toolkit I should use,which language is much better,which toolkit in python I can use.please told me.Thank you very much!!! Forgive me weak English.
I know there are some functions or methods to do image registration using Matlab.But they seem to be abstract, I did not find some underlying functions.I believe I can not do some modifications if I want to improve some algorithms.
Relevant answer
Answer
Maybe this youtube video may help you: https://youtu.be/TyV-9K_8w20.
  • asked a question related to Medical Image Registration
Question
6 answers
I am interested in obtaining a spectral CT dataset to test a reconstruction algorithm. 
Thanks. 
Relevant answer
Answer
  • asked a question related to Medical Image Registration
Question
6 answers
I am studying 2D and 3D registrations. I need help and guidance in producing DRR from CT images. Is there an article or program that fully explains how to generate DRR from CT images? .
I want to use CNN networks for registration whose input is a fluoroscopic and DRR images.
thanks
Relevant answer
Answer
Recently, I have tried to apply the same approach, along with textures as a co-author in oral cavity cancer classification: https://www.mdpi.com/1424-8220/20/20/5780, maybe it will help you, I know its different applications but can be applied to Ct images too.
  • asked a question related to Medical Image Registration
Question
10 answers
Hello!
I am working on segmenting cells from Fine Needle Aspiration (FNA) images of breast. Size and shape features of the cells segmented out of the microscopic sample image shall be determined. I intend to classify the sample using my algorithm based on these feature values. I am facing problem in finding a database that contains sufficient FNA images for breast cancer. If anybody have experience working in this area, please share. Furthermore what segmentation techniques can be used for this purpose.
Dr. Arbab Masood Ahmad
Relevant answer
Answer
There are numerous segmentation techniques: , FCM, EM algorithm, contour active and Level set.
You have this link for more information:
  • asked a question related to Medical Image Registration
Question
8 answers
I need a public benchmark MRI Prostate dataset for image registration/fusion. The dataset should be segmented with multiple segments per image i.e
1)Prostate gland
2)Peripheral zone
2)Central zone
3)Suspected Lesions
Thanks
  • asked a question related to Medical Image Registration
Question
5 answers
I have downloaded BRATS 2015 training data set inc. ground truth for my project of Brain tumor segmentation in MRI. A file in .mha format contains T1C, T2 modalities with the OT. Please suggest how to access these files in MathWorks (MATLAB) and further how to proceed for segmentation procedure?
  • asked a question related to Medical Image Registration
Question
1 answer
The challenge is based on the publication by Collins et al. (2017) appearing in the IEEE Transactions on Medical Imaging (vol. 36, no. 7, pp. 1502-1510) and is described by the SPIE Medical Imaging 2019 Proceedings paper please cite both of these if using data within a paper). To describe briefly, there are surgical workflow advantages if one could align preoperative liver image volume data to its intraoperative physical counterpart using sparse surface data visible during the procedure at presentation. We have developed a novel human-to-phantom framework that allows us to transpose real operating room (OR) data patterns that we acquired clinically using an optically tracked stylus onto a quantitative deforming phantom environment. This framework allows the development and testing of image-to-physical registration algorithms in the presence of deformation with quantitative subsurface targets for assessing error and within the context of realistic OR data acquisition. We note that the deformations we have imposed on the phantom mimic patterns of deformation we have seen in the OR. Specifically, the presentation of the organ allows the anterior surface of the organ to be visible at various levels of extent, and deformations are associated with the surgical packing of the organ on the posterior side of the organ. For this challenge, these states can be assumed. As part of this new challenge, we have developed a new phantom and more data patterns not previously used. We also have many more subsurface targets for characterization than in previous work (n=159 targets). In order to formerly enter your result for the challenge and have it posted on the Final Result Dashboard as complete, results need to be provided for all 112 data sets. You do not need to submit results to all data sets to interact with the challenge. The Dashboard will also track partial submissions, i.e. you can provide subsets for analysis while you are developing and these results will be provided on the Dashboard. Only latest results will be retained. *** Also, new to the challenge, on the data site, we do have sample results among the data set available so that you can check your algorithms before submitting to the dashboard.***
The challenge was officially released in February of 2019. With respect to official end-dates to the challenge, the intent is to leave this available to the community for an extended period of time. With sufficient participation, a review and analysis will be forthcoming.
Relevant answer
Answer
Our first extramural group submitted to the dashboard. Very excited.
  • asked a question related to Medical Image Registration
Question
5 answers
Hello,
Already we have some similarity metric such as MI, NCC, CR, etc, As needed for task purposes.
I want to know does anyone know what the best or newest similarity metric is to registering two multi modality images??
Relevant answer
Answer
@sonja
It was useful, thank you
  • asked a question related to Medical Image Registration
Question
3 answers
I know that in List mode data the scintillating events are stored along with the time stamps of the event. I have a doubt regarding image reconstruction from the list mode data.
Is each (x,y coordinate of) photon count binned into an image matrix or are the photon counts integrated in certain time interval and treated with Anger algorithm or MLEM algorithm then binned into a image matrix? If the latter is the case then what is the value of the time interval?
If my question is not clear or wrong can anybody suggest some sources which will help me in understanding this ?
Relevant answer
Answer
Can someone refer to any text or website that provides a step by step guide for image reconstruction in PET using list-mode data
  • asked a question related to Medical Image Registration
Question
5 answers
Dear colleagues,
We are pleased to announce the 9th International Workshop on Biomedical Image Registration, WBIR2020, hosted in Portorož, Slovenia! The workshop will be held in the Congress Centre Bernardin in Portorož, on 16 and 17 June, 2020.
The workshop brings together leading researchers in the area of biomedical image registration to present and discuss recent developments in the field, including methodological innovations and advances in the performance and validation on existing and novel applications. The workshop will include both oral and poster presentations, exciting keynote lectures, all with ample opportunities for discussion. At the social events you will enjoy the warm and relaxing Adriatic seaside along with authentic Mediterranean cuisine and excellent drinks.
IMPORTANT DATES Paper submission deadline: Jan 10, 2020 Notification of acceptance: Feb 21, 2020 Camera-ready deadline: March 20, 2020 Conference dates: June 16 and 17, 2020
AIMS AND SCOPE Submissions are invited in all areas of biomedical image registration. Topics of interest include, but are not limited to:
- Novel registration methodology: 2D/3D/4D, spatiotemporal/dynamic, pairwise / groupwise, slice-to-volume, projective, single/multi-modal, intra/inter-subject, model-based, patch-based, multi-channel, tracking
- Mathematical aspects of image registration: continuous/discrete optimization, real- time, similarity measures, diffeomorphisms, LDDMM, stationary velocity, inverse consistency, multi-scale
- Machine learning and deep learning techniques for registration: unsupervised / supervised / reinforcement learning, convolutional / recurrent / transformer networks, neural networks for feature extraction and matching, correspondence weighting and prediction, attention modeling, deformation learning, deep encoder- decoder networks
- Biomedical applications of registration: computer-assisted interventions, image- guided therapy, treatment planning/delivery, diagnosis/prognosis, atlas-based segmentation, label fusion, histopathology correlation, serial studies, pathology detection and localization, morphometry, biomechanics, image retrieval/restoration/fusion, imaging biomarkers for precision medicine, radiomics & radiogenomics, early proofs of concept
- Validation of registration: quantitative and qualitative methods, benchmarking, comparison studies, phantom studies, correlation to outcome, validation protocols and performance metrics, uncertainty estimation
All accepted full paper submissions will be published as a volume in the Springer's Lecture Notes in Computer Science (LNCS) series.
ORGANIZING COMMITTEE Ziga Spiclin, University of Ljubljana, Ljubljana, Slovenia Jamie McClelland, University College London, London, UK Jan Kybic, Czech Technical University in Prague, Prague, Czech Republic Orcun Goksel, ETH Zurich, Zurich, Switzerland
SPONSORS The WBIR 2020 is a MICCAI Society Endorsed Event (www.miccai.org).
Relevant answer
Thank you very much for sharing this announcement ... It seems interesting, a recent look at the site where it was announced about trying to find an alternative date to hold the conference, due to the Corona pandemic. I hope that you will inform us of any updates in the event of setting another date .. I hope goodness and safety For everyone...
  • asked a question related to Medical Image Registration
Question
5 answers
I am working on DWI images of GBM patients and I want to subtract ADC values of post treatment from ADC valuse of pre reatment images. I did not use any marker, how can I find the same slices for registration in two image sets?
Best Regards
Relevant answer
Answer
In my own experience when you use "mutual Information" as a cost function the result of the registration of two time-sets of ADC images is better (if you use FSL Flirt tool for this purposes).
  • asked a question related to Medical Image Registration
Question
8 answers
Hi all,
I'm interested in X-y location of a point on an image. If I interpolate the image to be 1000 by 1000 pixels, then downsample it to 200 *200 pixels. Then measure X-Y location of the point. Do the interpolation and downsampling generate an artifact that might affect the accurate x-y position of the point?
Relevant answer
Answer
hi wadha,
sure the location will be changed and in a simple calculation you can multiply the coordinated by the sizing ratio, in your example the sizing ratio is 200/1000 = 0.2, then you need to multiply the coordinates by 0-.2
best,
Mohammad
  • asked a question related to Medical Image Registration
Question
9 answers
Why do we need to down sample the histology image when we try the registration to a medical image?. one reason that I know is to reduce the noise. Also, to help the similarity metrics to find a corresponding points then robust the registration. I would know if there is more significant reasons.
Thanks,
Relevant answer
Answer
Yes, could you elaborate on what you want to do?
Histology images (in my experience) have much more pixels per centimeter. But that should not be a problem for registration: the registration method should not assume equidistant pixels in the two modalities. Registration speed is faster when down-sampling. Noise is usually low in histology images.
A problem is to get a good starting point for the registratio. Keeping track of where and in what orientation the (stack of) histology slices are made, is not easy. Another problem is that tissue deformations can be huge, so the transformation of for example MRI to histology is not linear. You need deformable registration.
Having mentioned some problems, I want to add the great value of such (for example post-mortem) registration: in cancer research it provides the only evidence of tumor extent. So, important work!!
  • asked a question related to Medical Image Registration
Question
4 answers
I'm facing a difficulty in evaluating the registration accuracy by using Elastix, since I'm using an artificial images.
I would like to have an advice on how to evaluate the accuracy of the registration process.
Thanks
Relevant answer
  • asked a question related to Medical Image Registration
Question
6 answers
A detailed study of medical image registration technique with application and validation. I am looking for suggestion to select a >1.4 impact factored and relatively fast review journal to send my manuscript.
Thanks
Relevant answer
Answer
Hi,
Have a look at
Current Medical Imaging Review
International Journal on Imaging Systems and Technologies
  • asked a question related to Medical Image Registration
Question
3 answers
We are working with lung images from LIDC available through The Cancer Imaging Archive.  The XML file provides the ground truth data.  Is there any possibility to generate ground truth images from the available data.
Relevant answer
Answer
@Rajeswari Rajendran:
Have you got any idea? I am using the XML file included in each case. but I wonder, how to map all 4 read in one slice?
  • asked a question related to Medical Image Registration
Question
7 answers
In the development of a Co-registration method to compare two 3D MRI exams (before and post chemotherapy treatment for one patient using the same MRI modality) ==>you can see the problematic on the image uploaded enclose<==. The results show a correct alignment at the visual level. However, this is surely not enough. The first thing I have to think about is to validate the findings by comparing the anatomical points of interest (Landmarks). Are there any more practical propositions?
I thank the community in advance.
Relevant answer
Answer
Probably the most reliable and clinically most relevant way of verifying registration results is to ask experts to identify the same landmark points in both the fixed and moving image and then compute the distance between the fixed and transformed moving points.
Similarly, you can segment relevant structures in both the fixed and moving image and compare the fixed segments with transformed moving segments. Hausdorff distance (mean, 95th percentile) is a good metric, tells you how well the surfaces of the segments are matched. Some people use Dice Similarity Coefficient for segment comparison, which is a very poor metric, as its value is highly dependent on shape of segments (but it's very easy to compute, probably that's why many people still report that in papers instead of Hausdorff distance).
Both point and segment based evaluation can be performed in 3D Slicer (http://www.slicer.org - free, open-source medical image visualization and analysis software).
For segment-based evaluation, install SlicerRT extension and use Segment Comparison module (it can compute both Hausdorff and Dice metrics).
For point-based evaluation, you create two markup fiducial lists, apply the computed transform to the moving list, harden the transform, and compute distances in Python - or save transformed point positions to file and compute distances in Excel, R, etc.
If you have any questions, post it to http://discourse.slicer.org, you typically get expert help within a few hours.
  • asked a question related to Medical Image Registration
Question
1 answer
Dear guys,
I'm looking for a data set containing both CT and MR images of Head:
* Task description: Implementing INTRA-subject CT-MR volumetric image registration.
* Data requirement: the field of view MUST include mouth regions (i.e.,  jaw, tongue, mandible, etc).
Thanks in advance for your suggestions and helps,
Relevant answer
Answer
For MRI data i always look in http://www.oasis-brains.org/
You can also look in https://radiopaedia.org/. the have so many images both pathological and nonpathological
  • asked a question related to Medical Image Registration
Question
2 answers
Fetal movement and nonrigid deformation of uterine organs are severe artifacts deteriorating in utero magnetic resonance imaging (MRI) of the moving fetus. Many image registration tools have been developed to correct motion artifacts in brain MRI, such as FSL, AFNI, ANTs, IRTK, Elastix, and so forth. Most of them are similar each other since they are based on common theories of image registration. Moreover, advances have been made to cope with the severe motion artifacts in MRI of the moving fetus during decades. I already have used some of existing tools for image registration in functional MRI of the fetus. But, has anyone quantitatively compared those tools for in utero functional MRI (for example, of the placenta and fetal brain)? Which image registration tool would you recommend for in vivo functional MRI of the fetal brain?
Relevant answer
Answer
Hello Christopher,
Thank you for your comments. I have known that PVR works well for super-resolution reconstruction of T2-weighted images. I tried PVR for functional MRI of the fetus, but it does not work well because it did not have multiple images necessary for reconstruction while T2-weighted images consist of coronal, axial, and sagittal directions.
Elastix seems to be superior to others for non-rigid body registration. However, it took too much computation time, and sometimes intensities were seriously distorted like fluid with salt and pepper noise. It might be attributed to my fault in configuration. In the end, I moved to IRTK. If you want to do just rigid-body registration, ANTs might be a good choice.
  • asked a question related to Medical Image Registration
Question
3 answers
I am working in image processing in the area of brain cancers. For evaluating my diagnosis algorithm I need a T2-weight MRI tumor brain database. if someone can help me in this way, please contact me.
Relevant answer
Answer
Yes Vahid,
Kindly use the link suggested by Shafagat it will be useful.
Thanks
  • asked a question related to Medical Image Registration
Question
1 answer
The noise properties of the CBCT images depends directly on the voxel dimension, so comparing CNR obtained on different systems without a proper scaling is not correct.
Reconstructing the same set of projection with different voxel size will allow to have an experimental relation between the noise and the voxel size itself, but without the possibility to recover the raw projections (system installed in clinical enviroment) this experimental approach is not possible.
Is there a teoretical method for that sacling/normalization calculation? The type of reconstruction (FDK or Iterative) will influence that normalization process?
Relevant answer
Answer
Dear Alessandro,
The selected voxel size will influence the CT image noise and consequently CNR as you had rightly mentioned. If I understood your question correctly, if you want to evaluate the impact of voxel size on image noise, you could simply compare the noise in an ROI from a uniform water phantom image reconstructed at different voxel sizes. This will allow relative assessment as you had desired, but this type of evaluation would be subjective as noise properties are typically influenced by the reconstruction technique, recon kernel, and the different pre-processing techniques your raw data is subjected to prior to reconstruction by the vendor's software. If you just want to compare CNR for images from different scanners, a simple solution would be to maintain a common voxel size and similar kernel type for the same scan object. As mentioned earlier, there may be other (black-box) variables that may be at play when comparing scanners from different vendors.
Kishore
  • asked a question related to Medical Image Registration
Question
6 answers
Please provide me some useful materials to have a basic understanding on any Image Registration based application
Relevant answer
Answer
Hi,
Image registration can take different forms depending on the domain it is applied to. For example, it is quite common to see research papers discussing the best approaches to register multi-modality scans (e.g., CT and PET scan images, rigid and non-rigid MR and CT registration, etc.). In microbiology, image registration can be helpful in visualising the response of cells under several conditions. In 3D reconstruction, in light microscopy, we did a work where we optimised the post-alignment values of tomographic projections for fine tuning 3D sectioning.
A good start for you to read could be the below slides.
 
Regards,
Abbas
  • asked a question related to Medical Image Registration
Question
3 answers
Previously, I manage to develop 3-D model of the lower lumbar spine from the MR image segmentation based on the full-color image slices from Visible Human Project. I believe the image was obtained from a cadaver in the supine position. I was wondering if there are any available resources (similar to the one offered by Visible Human Project) which are in extension and flexion state? 
  • asked a question related to Medical Image Registration
Question
4 answers
Rigid registration, although trivial, is often used as a pre-registration step in Medical Image Registration or Remote Sensing. I would like to know what are the current best methods with respect to :
i) computation time and
ii) precision.
Thank you in advance for your help.
Relevant answer
Answer
You can try this: Flexible Algorithms for Image Registration
  • asked a question related to Medical Image Registration
Question
3 answers
I am looking for various approaches for cancer segmentation and classification and was recently looking for Active Shape Model. The machine learning part of ASM is mainly based on Principal Component Analysis. I was looking for the feasibility of mixing ASM with deep learning? Can that be a feasible approach for segmentation pertaining to cancerous regions?
Relevant answer
Answer
Thanks Abdul, 
ASM has its own merits and demerits when applied to the particular problem. It has to be hybridized with some techniques , so was exploring Neural Nets in order to get more optimal results. 
  • asked a question related to Medical Image Registration
Question
2 answers
I urgently need any material that explains the general and basic standard for calculating lesion profile- the extent of vacuolation or spongiform degeneration.
Relevant answer
Answer
@ Dr Dick Terwel. l am grateful for the pdf you sent. Thanks for your prompt response to my request.
  • asked a question related to Medical Image Registration
Question
4 answers
is image geo-referencing and image registration is synonymous?
Relevant answer
Answer
Transforming one image geometrically so that it overlays on another image of the same area is called image registration. It does not necessarily include ground coordinate systems.  
However, in Geo-referencing, you assign ground coordinates to the pixels of any given image. In this case, you may need a bunch of GCPs to geo-reference your image. Or, if you have an already geo-referenced image, you can use that as a reference and register (using image registration) your image to the reference image. In this case, your final result will contain ground coordinates as well. 
  • asked a question related to Medical Image Registration
Question
3 answers
Local optima one of the optimization problems. while I am reading a MIND: Modality independent neighbourhood descriptor for multi-modal deformable registration paper I found the authors say: 
"The main disadvantage is that MI is intrinsically a global measure and therefore its local estimation is difficult, which can lead to many false local optima in non-rigid registration.The main disadvantage is that MI is intrinsically a global measure and therefore its local estimation is difficult, which can lead to many false local optima in non-rigid registration."
Relevant answer
Answer
Hi,
For measuring self-similarities locally (within a surrounding image region), and not globally see the following link
They use sum of square differences (SSD) between patch colors.
Hope this helps.
  • asked a question related to Medical Image Registration
Question
3 answers
I'm looking for MRI images prior to artifact corrections. Preferably the scans from different body areas.
Relevant answer
Answer
  • asked a question related to Medical Image Registration
Question
13 answers
I am applying OTSU segmentation algorithm in order to segment the skin lesions, so for some of the lesion images I am getting optimal segmentation results but for most of the images I am not getting segmentation properly.
for example-
1.Ideal Segmentation Result-
The first image shows original lesion and second image i.e. Sampe1seg shows its segmentation result which is ideal.
2.Not Ideal segmentation-
The third image is the original image of lesion and forth image shows the poor result of segmentation.
Relevant answer
Answer
Apart from the segmentation method itself, input images should meet the requirements of the segmentation method. You can try to preprocess your images to make them more suitable for Otsu.
For example, in the non-ideal segmentation result, you are getting a wrong mask because the ilumination in the image is not uniform (part of the backround in the right is darker, so it gets closer to the object of interest). You can try to correct that bias before applying the segmentation method.
  • asked a question related to Medical Image Registration
Question
3 answers
What do you think about normalization patients with tumors? I analyzed each individual patient usually and I didn't do normalization.  How best to proceed?
I would like to do analysis of ROI in different planes by using DPARSF program.
Relevant answer
Answer
Thanks for your help,
I am looking for new ideas for my research. I have little group: 6 patients pre and 6 patients post operative.
Ilona
  • asked a question related to Medical Image Registration
Question
4 answers
what are the new methods or techniques used for registration of MRI CT images? What are the different methods i can try by using image processing? I am focusing on accuracy, low computational cost and Speed. Please help me.
Relevant answer
Answer
Simply use the FSL software (free, accurate, easy to use, and fast). It has many modules for this including linear registration (FLIRT), non-linear (FNIRT), and warping, I have found the best technique is to use all 3 (first FLIRT, then pass the output to FNIRT, then pass that output to 'applywarp'). It will work well even on a low powered computer, but the better the CPU the faster it will be.
Regards,
Jerome
  • asked a question related to Medical Image Registration
Question
3 answers
I did my research in mathematics and i applied it for boundary of a medical image. I sent my paper to journal in computer vision and reviewer wrote that "A possible comparison would be against image registration methods, since the distorted image and boundary, after registration with the original image, would provide the original boundary". any body knows about image data in image registration?what does mean this commends?thanks n regards
Relevant answer
Answer
I'm not sure what you did. But with the image registration you find the transformation to  exactly superimpose two images. Thus, if you have an original image, a distorded one, if you register them you can identify the difference at the boundaries between the two images.
  • asked a question related to Medical Image Registration
Question
4 answers
i used matlab toolbox which use intensity based registration,
the image that i want to register to the reference image doesn't have good intensity, and makes algorithm not to work properly.
here is my two images
Relevant answer
Answer
Any chance the original used a mechanical cross hair marker? If not, try stretching the image in x or y i f you had variance on grazing angle. You can LPF after that.
  • asked a question related to Medical Image Registration
Question
7 answers
I am registered two images. For that, I stored images in matrix. Then I found inverse of one matrix which multiply with 1st image matrix. For multiplicaiton, first matrix's column must same with second matrix row. and it is not possible in different size of image. Can you solve this?
Relevant answer
Answer
Thank you
  • asked a question related to Medical Image Registration
Question
3 answers
Has anyone previously used K-nearest neighbour search method to verify co-registration of MRI Images? Greatly appreciate any insight into how this method can be applied for exactly that purpose.
Relevant answer
Answer
when you employ clustering with inhomogeneity correction the number of misregistrations is reduced without loss of accuracy thus increasing robustness as compared to the standard non-inhomogeneity corrected and equidistant binning based registration.
  • asked a question related to Medical Image Registration
Question
7 answers
I'm Interested in doing image registration of two mri brain tumor images, hence i need the tumor images i.e. in the initial stage and the extended/later stage of the same patient. so that i can determine the prognosis. Any relevant sites?? thanks
Relevant answer
Answer
The cancer imaging archive has a number of public imaging datasets including those containing MRI of brain tumors
  • asked a question related to Medical Image Registration
Question
3 answers
I'm Working on detection and classification of MRI brain tumor images, hence for classification i need the data sets of benign and malignant mri brain tumor images. Thanks
Relevant answer
  • asked a question related to Medical Image Registration
Question
3 answers
and how to evaluate using RIRE project?
I have developed my multi-modal image registration for brain images. What evaluation methods are the best for my application?
I came across to RIRE project (http://www.insight-journal.org/rire/information.php). I read some related articles, but it is a bit confusing for me and I do not know how to evaluate my method using it. I would be thankful if anyone could help me.
Relevant answer
Answer
Dear,
      Mutual Information is the best measure.
  • asked a question related to Medical Image Registration
Question
5 answers
what are the new trends for medical image classification. In other words, what are the current works on medical images ?
Are there any standard medical dataset?
Additionally, what are good feature selection methods for such type of datasets?
Thank you.
Relevant answer
Answer
Yes, there are many standard datasets but which medical images you mean?
There is standard Digital Image Database for lung nodule
Liver segmentations
Also, brain tumor segmentation
  • asked a question related to Medical Image Registration
Question
4 answers
i am doing research on texture and shape feature for brain tumor images. so i need a latest techniques used in texture and shape features.
Relevant answer
Answer
  • asked a question related to Medical Image Registration
Question
2 answers
Contrast agent for CEUS: SonoVue
1,5 Tesla MRI
Relevant answer
Answer
Yes of course there are some. Here below is one ref but you could find others easily.
Solid focal liver lesions indeterminate by contrast-enhanced CT or MR imaging: the added diagnostic value of contrast-enhanced ultrasound.
Quaia E.
Abdom Imaging. 2012 Aug;37(4):580-90.
  • asked a question related to Medical Image Registration
Question
5 answers
Dear sir
I converted MRI dicom files to nii  file using  dcm2niigui.
Previously i used same program for my data, then i got one nii images.
But this time, i got 3 nii images. 
one image name is sample.nii (22,529KB), the other is osample.nii(22,529KB) and the last one's name is cosample.nii (13922 KB).
I wonder what kind of image do i use for my further analysis.
If you have some idea, please help me.
Relevant answer
Answer
sample.nii for sure
  • asked a question related to Medical Image Registration
Question
7 answers
Hello everyone, I'm working on a computer vision project in which I have to do segmentation of cervical spine vertebras and after that I have to track these segmented Vertebras in the whole fluoroscopic video sequence. I am done with the segmentation part and now I want to track those vertebras, any suggestions for tracking algorithm? video file is attached here.
Relevant answer
Answer
In my research I had once used the anisotropic diffusion for the MRI medical images. See if it helps u
  • asked a question related to Medical Image Registration
Question
5 answers
Is there a well established methodology to register two different 3D microscopy images ?
I'm currently working with confocal 3D+Time acquisition in vivo, but I need to find a way to register the stacks from different time frames. For 2D registration we have lots of libraries,  but register  each 2D layer independently is out of question, because of movement in Z direction.
Any clues ?
Best regards
Relevant answer
Answer
Unfortunately outwith my knowledge
  • asked a question related to Medical Image Registration
Question
14 answers
I have some DICOM images for testing and discovered some tools like Invesalius, (Seg3D; Biomesh, from SCI/Utah) and Gmsh. However, could some one give me a hint on other softwares - or even the trick - about how to segment the images in order to have both marrow and bone exported as a volume ready for FE processing?
Relevant answer
Answer
Hi Gustavo,
all the segmentation tools mentioned above are good, personally I like Seg3D but in order to produce meshes (e.g. in STL file format) for subsequent FE analysis you need different tools. Take a look at the Winged Edge Mesh (WEM) tool in MeVisLab (www.mevislab.de), I've found it very useful and you can also smooth the mesh at a desired level. Other corrections on mesh files (e.g. vertex editing, missing points) can be done with MeshLab (http://meshlab.sourceforge.net).
  • asked a question related to Medical Image Registration
Question
1 answer
I want to study aneurysm growth (in volume) in a set of subjects, based on Time of Flight images (MR) images at two time points.
For each subject, I want to do a rigid registration between time of flight images as well as a segmentation of the cerebral vascular system. And then, I want to compare the two registered segmentation volumes in order to quantify the aneurysm growth.
For doing this, some teams used in-house registration tools (not distributed as far as I know, AnToNIA for ex) and the registration is performed using a volume of interest around the aneurysm sac (and not using the whole brain).
I currently know free registration tools not specific to aneurysms (FLIRT of FSL for exemple: http://fsl.fmrib.ox.ac.uk/fsl/fslwiki/FLIRT). Additional question: Do you think these kind of methods is appropriate to do "aneurysms registration" ? 
Thanks in advance,
Relevant answer
Answer
If you are willing to get into a bit of programming, you could try the vmtk libraries (http://www.vmtk.org/). The authors would probably mix in 3d Slicer for free registration and visualization. They seem now to have a commercial offering which presumably makes life simpler, but not free. 
  • asked a question related to Medical Image Registration
Question
3 answers
I need it for image registration and dose distribution applications.
Relevant answer
Answer
The Cancer Imaging Archive has a number of different types of phantom data sets available for free download which might also be of use to you: http://www.cancerimagingarchive.net/.
  • asked a question related to Medical Image Registration
Question
3 answers
I am trying to register US image and CT scan image of cardiac. CT images are in axial plane, however, the US images are in parasternal view( sagittal plane). Is there any methods that can I use to do this registration or I have to acquired the US images in same plane as the CT images? Please help me.
Thank you. 
Relevant answer
Answer
In 3D Slicer, you just load the two volumes and use the General Registration module to perform rigid, affine or BSpline registration. No extra steps are necessary, just tuning the registration parameters to your needs (such as decreasing % of samples)
  • asked a question related to Medical Image Registration
Question
2 answers
What is a reasonable distance in mm when applying registration on longitudinal mammograms images ? I would like some state of art measure or personal opinion of some clinical/radiographic specialist.
Relevant answer
Answer
As I stated earlier,  the interested distance was in mm (measure closer to clinicians). I found something from 2 to 4 mm. Something in a real setting definitely will be larger than 1 pixel. The standard is 5 pixels per mm. 
  • asked a question related to Medical Image Registration
Question
5 answers
Dear all, I would like to ask you something about current research in medical image registration. Could you give me some current major challenges and issues in medical image registration, especially stained histological sections (different dye per section). Do you know where would be possible to get some more data to work on? Thanks
Relevant answer
Answer
I have already worked on medical image registration. the first and the most important challenge in rigid body image registration is finding a good similarity measure. This measure should be maximized in order to achieve best alignment between two images. mutual information is one of the est examples. the second challenge is the optimization method by which we want to find transformation function parameters. Most of the optimization methods converge to local maximums which is not desired.
here you can find good medical image data;
good luck
  • asked a question related to Medical Image Registration
Question
10 answers
Can anybody suggest an Image registration method with available implantation for and benchmark comparison on medical images? I found couple: ITK, Elastix, bUnwarpJ, TurboReg... Some other suggestion?
Relevant answer
Answer
Btw, so far I know the DEMONS works only with segmented images (foreground background), doest it?
  • asked a question related to Medical Image Registration
Question
4 answers
I am doing research on deformable medical image registration. How can I evaluate the performance of multimodal registration methods. Since the spatial correspondence is unknown for multimodal images.
Relevant answer
Answer
If you want to evaluate the performance of a registration method and you have the images, the most common way for medical images is to compute evaluation indices between structures of interest: DICE Similarity Coefficient (DICE), Maximum Distance (DMax), Averange Simmetry Distance (ASD), and others.
If you do not have the images, it is difficult to find a database for the evaluation of multimodal non-rigid registration.
- RIRE Project database is only for Rigid Registration evaluation.
- POPI Model database is for Non-rigid registration, but it is only for Monomodal images.
- NIREP is an other option for non-rigid registration evaluation, but is only over MR images.
- Other option is to generate yours ground truths with  synthetic deformations over pre-aligned images.
Good luck!
  • asked a question related to Medical Image Registration
Question
2 answers
I am curious to know how VTK estimates the transformation matrix in the VTKLandmarkTransform method? Does it involve a solution of equations given a minimum set of points in the source and target OR does this estimation (estimation of transformation matrix) involve some sort of optimisation, for example, optimising the fiducial registration error?
Thanks in advance..
Relevant answer
Answer
From the second link, I gather that between the two point sets, it assumes ordered correspondences. So the mapping is not optimized.
In VtkLandmarkTransform.cxx I encountered the use of JacobiN(); an iterative optimization algorithm.
If you know of a method that also optimizes the mapping, without getting stuck in local minima, I'm very interested.
  • asked a question related to Medical Image Registration
Question
9 answers
I am doing research on processing medical images which contain some cells which adhere to other cells. Considering the fact that I should extract the cell’s number, I need to find a method in order to make these cells separated.
It would be kind of you to give me your valued suggestions.
Thank you.
Marjan
Relevant answer
Answer
I have done such a project as my B.Sc. thesis before. you can use structuring elements so as to to do this. the following link provides you a good introduction to structuring elements. 
please also see structuring elements in Matlab help
  • asked a question related to Medical Image Registration
Question
4 answers
Can PCA based dimensionality reduction be used as preprocess ?
Relevant answer
Answer
In a recent paper (Toutounji and Pipa 2014), we used the the algorithm and code by Kraskov A, Stogbauer H, Grassberger P (2004). Mutual information on multidimensional sources is computed by an adaptive k-nearest-neighbor estimate of probability density. Our sources where 9D input sequences to a recurrent binary neural network and the response of the 100 neurons comprising the network. Given the high dimensionality of the recurrent neural network, one needs many samples to have an accurate estimate, which results in a huge computation time. It was thus necessary to use PCA on the synthetic data and choose only those components that covered 95% of the information.
In the attached link, you can download the executable binaries, the source C code, and MATLAB rappers, all made available by the authors.
I hope that helps.
  • asked a question related to Medical Image Registration
Question
6 answers
GPU based image registration ?
Relevant answer
Answer
Phase correlation works very fast and flawlessly on GPUs.
  • asked a question related to Medical Image Registration
Question
11 answers
I am acquiring image sets from both modalities in an attempt to use the resolution of CT and the soft tissue contrast of MRI for more accurate pathological tissue characterization. I am not sure whether I need to limit my FOV in the MRI to the lowest setting of our uCT in order to be able to do meaningful image analysis. Any help would be greatly appreciated.
Relevant answer
Answer
Given that the image modalities use a totally different type of physics to generate the images you are under no compulsion to limit FOV, resolution or other parameters. Your first task will remain producing an accurate transformation between the to FOV at the appropriate coordinates where the tissue to be correlated has the same volume element.
Structurally we will see more soft-tissues structures with MRI than CT. CT without a contrast does relatively poorly on separating continuous soft tissue.
Fixing the FOV, resolution, etc to be the same size may help at first glance to help co-register the two images. However, since the transformation from one image space to another will not be analytically exact for these values and the MTF for each images will be different you are best served having as much resolution to work with to "fit" the image spaces together before cross-correlation.
  • asked a question related to Medical Image Registration
Question
1 answer
Intensity based, mutual information.
Relevant answer
Answer
  • asked a question related to Medical Image Registration
Question
11 answers
I have 6 spectral channels, every channel as an independent image.
I want to make an RGB image, I need a formal method or scientific proof for this making method.
Relevant answer
Answer
ImageJ (http://rsb.info.nih.gov/ij/ ) can easily merge up to 7 image channels into a single RGB image. You have control over the ordering and the color of the channels. It's also possible to use the OME (Open Microscopy environment) to produce similar results. ImageJ would be simpler to setup and use.
  • asked a question related to Medical Image Registration
Question
5 answers
I want to apply a shape-based template matching detection
Relevant answer
Answer
Whether you need contrast enhancement really depends the quality of your images. I have got away without doing any enhancement in some MR images.
I think you might want to normalize the image intensities though. Otherwise you may have to retune your edge detection parameters each time for a new image, especially if they are acquired using different machines.
  • asked a question related to Medical Image Registration
Question
2 answers
Can I register a pair of CT brain images using cubic b-spline in hierarchical form for monomodal image registration?
Relevant answer
Answer
Its will be an honour,i have just visited the website but not able to find any last dates for submission
regards
Madiha Azam
  • asked a question related to Medical Image Registration
Question
4 answers
As I am doing my research on non rigid registration of brain MRI images
Relevant answer
Answer
Ok thanx Daniel for this valuable suggestion.
  • asked a question related to Medical Image Registration
Question
1 answer
I am doing research in nonrigid registration of brain images, now first I want to implement my code on 2D images as my code is for multimodal registration
Relevant answer
Answer
Hello Madiha. You can obtain 2D an volumes images of the brain in CT/MRI perfectly aligned in these web: http://brainweb.bic.mni.mcgill.ca/brainweb/ , is a brain web simulator. I'm working now with non-rigid multimodal registration, and hopefully in the future we can share experiences and knowledge about image registration. Greetings!