Medical Biotechnology - Science topic

My Dear you apply for Canada visa and jobs along with resume.i can say that you can get there higher education with scholarship as you are scholar.

Very happy for your valuable open letter.i do not know in your united Arab Emirates citizenship.

Ok proceed.

I am very interested.

I have research and interests in medical genetics on a less laboratory research results level. I rely on the scientific research in Atlas of Genetics and Cytogenetics in Oncology and Haematology nonetheless. Congratulations on your ambitious and important research project! Best regards.

Does someone know which tubes can be used that are resistant to damage induced by homogenization in organic solvents?

Papers on RG:

Psychological consequences of IVF fertilization – Review of research

A big issue in antibiotic drug research and development these days has to do with the economics of introducing a novel antibiotic into the market when cheap generics are already available. The new drug may be better in some sense (e.g. fewer bacterial strains are resistant to it, or it is less toxic than the older drugs), but the hospitals won't use it very much because it is more expensive, and they won't be able to get sufficiently reimbursed by the insurance companies. Or antibiotic stewardship dictates that the new drug should be "saved" for use only when the cheaper drugs fail. As a result, companies that have completed the clinical trials and manufactured the drug can't sell enough to cover their costs. For some small companies recently, this has caused severe, even terminal, financial hardship. There is legislation pending in the US Congress to try to address this issue, because it is stifling the discovery, development, and use of new antibiotics to address the issue of drug resistant bacteria.

CRISPR /Cas9 has been implemented for editing human embryos

Ma H, Marti-Gutierrez N, Park SW, Wu J, Lee Y, Suzuki K, et al. Correction of a pathogenic gene mutation in human embryos. Nature. 2017;548:413–9. 7

See also,

Fogarty NM, McCarthy A, Snijders KE, Powell BE, Kubikova N, Blakeley P, et al. Genome editing reveals a role for OCT4 in human embryogenesis. Nature. 2017;550:67–73.

You mean there is a need of physiochemical bonding between between drug delivery polymer system and vascular stent metal and why it is needed, as currently the vascular stents are delivered to the target site mechanically.  

Hello

Look at links here will help you 

Good Luck 

In general, SPE cartridges are packed with the same type of packing (C18, amino, diol...) as your analytical column.  Thus, I would 1st look at the websites of analytical column manufacturers (Waters, Agilent, Phenomenex...) for what will work for you.

Dear Pavel.

We didn't try to analyze the serum of the same patient, but we measure SOD in serum by this method in routine and results are always OK.

Maybe is also relevant that we measured glutathione peroxidase (GPX) and total antioxidant status (TAS) on the same analyzer from the same manufacturer in the same follicular fluid and we got good results.

Best regards

Teja

Classically, the aortic root diameter and the left atrial antero-posterior diameter are measured from m-mode in PLAX. The advantages are being reproducible, high temporal resolution, wealth of published data, and no need for associated ECG recording to detect the systole and diastole. This method is applicable in most of patients. However, in some patients we may need to measure from m-mode PSAX or from 2D. In case we thought the left atrium is not normal we may need to measure the LA area or volume as the antero-posterior diameter represents a single dimension and not representative of actual LA size (particularly in dilated atria).

Thank you. I don't have ground truth data. I used original images from hospital.

Hi Rob

Citrate is the recommended anticoagulant for plasma to be used in coagulation tests. 

By definition, plasma has to be anticoagulated – if it isn’t, the blood clots and you end up with serum, which is deficient in clotting factors.

Regards, Rosemary

What you are in fact measuring is the alkalinity of your solutions. From which you can calculate your carbonate and bicarbonate concentrations. But the alkalinity consists not only of the carbonate and bicarbonate concentrations. 

Alk = [HCO3−] + 2[CO3−2] + [B(OH)4−] + [OH−] + 2[PO4−3] + [HPO4−2] + [SiO(OH)3−] − [H+] − [HSO4−]

I think that Niket need to explain more about the question. 

Where is in which forging, in which country?

Which are the shape and the dimensions of the part?

For deciding the type of mother wavelet, you look for two key characteristics, these are: 1) shape of the mother wavelet. Ideally, it should look like the signal you want to represent. Example: coif1 i.e. coiflets 1 better represent the oscillatory nature of PPG signal. Refer: http://ieeexplore.ieee.org/xpl/login.jsp?tp=&arnumber=7359311&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Farnumber%3D7359311

2) the bandwidth of the mother wavelet. This decides how much your wavelet will spread.

Now deciding the number of decomposition levels completely depends on the minimum sub-band you want the signal to be represented. Example: For a signal of sampling rate = 1000 Hz if you want to see the signal within < 30 Hz. then, the DL using DWT can be 4. Refer: http://users.rowan.edu/~polikar/WAVELETS/WTpart1.html

Transdermal drug delivery is not a trivial matter.  Drugs chosen for transdermal delivery are generally quite small molecules that are active at very low doses.  Sucralfate just isn't the kind of drug that suggests itself for transdermal delivery.

When applied to a mucous membrane, or indeed an ulcer on a mucous membrane, sucralfate probably doesn't penetrate at all.  It would be even less likely to penetrate intact skin.  So, why do you want to formulate an ointment or solution containing sucralfate, I wonder?  The only way in which you will get it to penetrate would be by seriously disrupting the integrity of the skin with a solvent such as dimethyl sulfoxide or sodium lauryl sulfate.  I wouldn't want that doing to my skin!

Most members of the Shelterin Complex (TRF1, TRF2, Rap1, TIN2, TPP1, POT1) will have some effect on telomere loss/stability.  CST complex (CTC1, STN1, TEN1) also has some effects at telomere ends related to replication.

Bone is Ca++ salts. Ca++ salts do not melt, they dissolve.

You have been watching too much TV.

.

 DARPins have been developed in the Lab of Andreas Plückthun http://www.bioc.uzh.ch/plueckthun/index.php?pid=2-1-0. They are being commercialised by Molecular Partners http://www.bioc.uzh.ch/plueckthun/index.php?pid=2-1-0 . DARPins against a variety of interesting targets are being generated for the Affinomics Project http://www.proteinbinders.org/index.php. See this paper for  a recent review: Plückthun, A. (2015). Designed Ankyrin Repeat Proteins (DARPins): Binding Proteins for Research, Diagnostics, and Therapy. Annu. Rev. Pharmacol. Toxicol. 55, 489-511. The original design of the DARPin library was published in this paper: Binz, H. K., Amstutz, P., Kohl, A., Stumpp, M. T., Briand, C., Forrer, P., Grütter, M. G., and Plückthun, A. (2004). High-affinity binders selected from designed ankyrin repeat protein libraries. Nat Biotechnol 22, 575-582. You find the full text of these (and many other) papers here: http://www.bioc.uzh.ch/plueckthun/index.php?pid=3-2-13 

You should filter before use

HI

the best supplier for 3d - Printing material is http://3d2print.net/ - high quality and acceptable price.

works good in makerbot Rep.

I would suggest ABS for your purpose.

Please let me know if it workes!

I'd say it depends on the workup (batch or continuous) and if you can maintain a sterile production line for a longer time and what you'd do if there is a problem (technical or sterility). Maybe 2 or 3 batch reactors, run in parallel or alternated/time shifted may get you on the safer side.

The question has been asked many times and in different forms.

The approach using a cutdown to introduce the lead directly or with guidewires and dilators into a vein that is somewhat small is superior to subclavian or axillary venipuncture not only in terms of safety for the patient (no pneumothorax, no hemothorax), but also in terms of lead longevity.

See this report by Dr. Parsonnet and Roelke. Interestingly, Dr. Parsonnet was one of the first authors who reported on the use of peel-away introducers.

Pacing and Clinical Electrophysiology

Volume 22, Issue 5, Article first published online: 30 JUN 2006

Dr Furman and Gross and their co workers described a similar problem with defibrillator leads in

Lead fracture in cephalic versus subclavian approach with transvenous implantable cardioverter defibrillator systems.

Gallik DM1, Ben-Zur UM, Gross JN, Furman S.

Pacing Clin Electrophysiol. 1996 Jul;19(7):1089-94

I hope this helps. The references are by no means exhaustive but from very well respected sources, two of the founders of the Hearth Rhythm society, then called "NASPE".

It really pays in the long run to learn to do cephalic cutdown and to use it as your preferred approach.

Thank you,

Jorge Camuñas

LHRH Analogue called NAferelin acetate has widely been accepted USFDA aaproved drug other than any biosimilar. It is modified nine-mer synthetic peptide. I am not aware of any phytochemical for the same.

OSDDlinux include number of software packages important for drug discovery

Cancerdr

Some approaches are

Regards,

Joachim