Maintenance - Science topic

You need to do method troubleshooting to see if it is the HPLC condition or the MS condition that causes the problem. Please inject your four std that you missed to the MS (with no column) to prove that the MS setting is still good. If you see the signal at the expected response (good signal), then you can focus on the column. If your MS is good, inject the same std with column and use the highest organic mobile phase to elute the compound quickly near the solvent front to prove that your column does not affect your analyses. Let me know the results and we can go from there.

The cost savings for Predictive Maintenance come from less uplanned downtime of equiepment. The idea is we can detect an impending failure of an item, such as through noise moitoring of bearings. As an example, if you can determine an impending failure is going to happen in the near future, then you have some time window to fix the issue. In the mechanical example of a bearing, perhaps there is a contaminant in the oil. Changing out the oil is a lot easier job than replacing a bearning. Most person;s automobiles monitor the state of the oil in the care and determine how much 'Oil life" is left, verus doing an oil change every 3000 miles.

Such predictive maintenance can reduce overtime costs of fixing a failure versus preventing a failture. "You can pay me now, or pay me later".

Camilla S.A. Davan Wetton : I would love to hear some of these tricks if you have figured out what they are. We are trying to use Lonza primary heps ( plateable) and they say these cells cannot be passaged as they are non proliferative. Additionally, culture can be done till 5 days. is there any way to expand these cells . The vials are extremely expensive and we experiments that may require more than one vial. Any help is greatly appreciated.

Thank you, Dave Dave Price

As a component MRO trader, I believe that if the MRO has access to customer data, including fleet sizes (both present and future), operational data (to examine seasonal factors and utilisation), and other data, they can optimise their inventory stocks. What do you think about this

Significant issues in existing software engineering include:

Other issues might include burnout among developers, inadequate documentation, and insufficient focus on user experience.

If your project is particularly large and complex, I recommend starting with CapdetWorks or WaterCAD to manage the multi-phase estimation and then using additional tools like Civil 3D for detailed design and modeling.

Thank you for the insights, Ciaran Daly! I'll consider lentiviral transduction as a possible solution if other approaches don't yield the desired results. I appreciate you directing me to your paper for more details. Thanks again!

Saad Hussein Murad Dietary supplements that may help manage psoriasis include omega-3 fatty acids, found in fish oil, which can reduce inflammation and improve skin health. Vitamin D supplements may also be beneficial, as they help regulate the immune system and skin cell growth. Antioxidants like vitamin E and selenium can protect against oxidative stress, which is linked to psoriasis flare-ups. Some people find relief with turmeric (curcumin), known for its anti-inflammatory properties. Additionally, probiotics might support gut health, which is increasingly recognized as playing a role in immune response and skin conditions like psoriasis. Always consult with a healthcare provider before starting any supplements to ensure safety and effectiveness.

Dear Doctor

[Annual lift maintenance tasks

Articles of Detection and Maintenance of Road Infrastructure Using Advanced Technologies

Road Structural Defects Detection and Digitalization Based on 3D Ground Penetrating Radar Technology: A State-of-the-art Review

Review of Deep Learning-based Crack Detection for Civil Infrastructures

Research on Cooperative Performance of Built-in Strain Sensor and Asphalt Pavement Structure

Surface Texture Reconstruction and Mean Texture Depth Prediction Model of Asphalt Pavement

.

Review of Deep Learning-based Crack Detection for Civil Infrastructures

APPLICATION OF AI ACROSS VARIOUS FUNCTIONS ACCELERATES THE POTENTIALITY OF THE TALENTED /COMPETENT WORKFORCE THOSE WHO HAS ZEAL AND ASPIRATION.

IT IS AN INTEGRATIVE FUNCTION ; SYSTEMATIC COOPERATION AND COORDINATION ; HR FOCUS ON THE DEVELOPMENT OF THE ENTIRE FUNCTIONS THROUGH THE INDUCTION OF THE LATEST TECHNOLOGY THAT FINALLY RESULTS IN IMPROVEMENT OF INDIVIDUAL PERFORMANCE, PRODUCT QUALITY AND FINALLY THE OVERALL PRODUCTIVITY.

Identifying research gaps in telematic technologies for road pavements optimization involves examining current advancements and pinpointing areas needing further exploration. Here are some research gaps in this field:

By addressing these research gaps, the field of telematic technologies for road pavements optimization can advance significantly, leading to more efficient, cost-effective, and durable road infrastructure.

Articles of Detection and Maintenance of Road Infrastructure Using Advanced Technologies

Road Structural Defects Detection and Digitalization Based on 3D Ground Penetrating Radar Technology: A State-of-the-art Review

Review of Deep Learning-based Crack Detection for Civil Infrastructures

Research on Cooperative Performance of Built-in Strain Sensor and Asphalt Pavement Structure

Surface Texture Reconstruction and Mean Texture Depth Prediction Model of Asphalt Pavement

.

Review of Deep Learning-based Crack Detection for Civil Infrastructures

Pharmacological agents used for induction, maintenance, and emergence from anaesthesia in paediatric patients are selected based on factors such as age, weight, medical history, surgical procedure, and individual patient response. Here's an overview of commonly used agents for each phase of anaesthesia:

These pharmacological agents are selected and administered by anaesthesia providers based on individual patient characteristics, surgical requirements, and institutional protocols to achieve optimal anaesthetic depth, analgesia, and recovery in paediatric patients undergoing surgery. Close monitoring and titration of anaesthetic agents are essential throughout the perioperative period to ensure patient safety and comfort.

For federal transport infrastructure planning, you will find the necessary information about the costs and benefits of the transport infrastructure in both Bundestag documentation and the method manuals for the federal transport infrastructure plans. However, the actual costs usually differ considerably. See the following links

The switch from gel separatory serum tubes to lithium heparin gel tubes may involve several cost implications, including Tube Procurement, Disposal Costs, Equipment Adjustments, Training and Education, Validation and Quality Control, Transition Planning and Communication, and Long-term Cost Savings.

Overall, evaluating the potential cost implications of transitioning to lithium heparin gel tubes requires a comprehensive analysis of procurement costs, disposal expenses, equipment adjustments, training and education needs, validation requirements, and communication efforts to ensure a successful and cost-effective transition process.

The C6/36 cell line is a mosquito cell line commonly used in virology and molecular biology research. The preparation of culture medium for C6/36 cells typically involves using a basic cell culture medium supplemented with additional components. Here's a general recipe for C6/36 cell culture medium:

firstly, we need:

->Basal Medium:

- Common basal media for insect cell lines include Grace's Insect Medium or Schneider's Drosophila Medium. Choose a medium suitable for C6/36 cells.

-> Serum:

- Fetal Bovine Serum (FBS) is commonly used as a supplement. The concentration may vary, but a common range is 5-10%.

->Antibiotics:

- Penicillin and streptomycin are often added to prevent bacterial contamination. Use concentrations like 100 U/mL penicillin and 100 μg/mL streptomycin.

-> Buffering Agent:

- Sodium bicarbonate or HEPES can be added to maintain the pH of the medium.

-> Additional Supplements (Optional):

- L-Glutamine, non-essential amino acids, and vitamins may be added depending on the specific requirements of your experiments.

To prepare the medium:

1. Prepare Basal Medium:

- Follow the manufacturer's instructions to prepare the basal medium. Ensure it is properly buffered to maintain pH.

2. Add Serum:

- Heat-inactivate the FBS at 56°C for 30 minutes if required. Add the desired concentration of FBS to the basal medium.

3. Add Antibiotics:

- Add penicillin and streptomycin to the medium. Mix well.

4. Adjust pH:

- If using a medium that requires additional buffering, adjust the pH to the recommended level using sodium bicarbonate or HEPES.

5. Sterilization:

- Sterilize the medium by passing it through a 0.22 μm filter to remove bacteria and other contaminants.

6. Storage:

- Store the medium in aliquots at -20°C or -80°C for long-term use. Thaw before use and avoid repeated freeze-thaw cycles.

To save media cost the base media can be diluted 1:1in dmem

Hi,

You could find it in "NASA's Open Data Portal"

Best

Answer lies in formulation of your problem, if you are placing the limits for 24 hours (short term) then both maintenance and capital cost become less in comparison to operational cost. Problem of scheduling is complex, lots of data is involved, specially when its OPF. If renewables are also considered then problem becomes stochastic again with additional methods (Monte Carlo etc.). I have never read a research paper considering all the possibilities of constraints. Better is to go ahead with: (Thermal Generators+Renewables+ Storage) in security constraint environment.

I don't have first hand information, but I would think VR will be a good way to give people an experience of driving the vehicle before buying the car.

Shaista Khaliq after source cleaning and maintenance.

Dear Juhi Naseem . There should be a comprehensive legislation to recognize live in relationships that consider each member of a family. So as each member be treated in a fair way.

Good question, indeed.

As practitioners, we always recommend to ...

1.

Define your system ("Define the Context") according to ISO 31000.

Because you need to know for which system (only) you are preparing your Predictive Maintenance Program.

How can you do that?

Please see e.g. one of our LinkedIN Posts (Post No. 16)

[https://www.linkedin.com/posts/alfred-moergeli-6919296_riskmanagement-context-activity-6686977016643756032-z3NC?utm_source=share&utm_medium=member_desktop].

2.

Define the A/B/C components of your system through a System Safety Analysis (SSA).

Because you need to know the critical parts of your system.

How can you do that?

Please see e.g. our LinkedIN Post No. 48

[https://www.linkedin.com/posts/alfred-moergeli-6919296_riskmanagement-whichsystemsareessential-systemsafetyanalysis-activity-6770644847570243584-5X3n?utm_source=share&utm_medium=member_desktop].

3.

Start to plan your Predictive Maintenance Program.

Because without a Road Map there never ever will be any kind of successful action.

How can you do that?

Please see e.g. our LinkedIN Post No. 5

[https://lnkd.in/edNdraJS]

with options for - Maintenance Plus, or - Retrofit/Revamp, or - Replacement.

How do you come along with that?

Very much looking forward to your feedback.

Thank you,

Alfred

I work with children with autism, and during the Covid-19 period we were working remotely and this had a good effect on some children in learning through the parents and the family, but it had a negative impact on others as some families do not work on training the children This training is given to both the teacher and staff. But the institution was very keen to provide the service in the best way and to the fullest and without stopping.

From my point of view, I believe that in the event of exceptional circumstances such as these, our solutions must be alternative, and the constant search for alternatives must be non-stop.But I always like to work face to face

The threshold value for an alert notification is determined by the specific criteria of the alert. Generally, this value is determined by evaluating the data that is being monitored and establishing a range of values that will trigger an alert. For example, if you are monitoring server performance, you may set an alert threshold value of 80% usage to trigger an alert when the server reaches that level.

This is a very important comment -- ChatGPT will make up fictional citations in many of its responses. Why they programmed it do this may be answered here:

Spillway is designed for the maximum flood that the structure can safely pass ‘design flood’ and is

selected after consideration of economic and hydrologic factors.

Design flood may be arrived at by considering the cost of constructing the structure to provide flood control and the flood control benefits arising directly by prevention of damage to structures downstream, disruption of communication, loss of life and property, damage to crops, and underutilization of land and indirectly, the money saved under insurance and workmen’s compensation laws, higher yields from intensive cultivation of protected lands and elimination of losses arising from interruption of business, reduction in diseases resulting from inundation of flood waters. The direct benefits are called tangible benefits and the indirect benefits are

called intangible benefits. The design flood is usually selected after making a cost-benefit analysis

and exercising engineering judgment.

Maximum Probable Flood (MPF) includes extremely rare and catastrophic floods and is usually confined to the spillway design of very high dams.

Refer to the book Hydrology by H.M.Raghunath

You can also refer to many hydraulic structures books.

1. Autonomous Rendezvous and Docking: Autonomous rendezvous and docking technology enables spacecraft to autonomously dock at a specified point in space, allowing for maintenance and repairs to be performed remotely.

2. On-Orbit Robotic Servicing: On-orbit robotic servicing technology enables spacecraft to be serviced and maintained remotely, eliminating the need for astronauts to travel to each craft in order to perform maintenance.

3. Teleoperated Robotics: Teleoperated robotics technology enables spacecraft to be controlled remotely, providing greater flexibility and responsiveness to changes in the environment.

4. Satellite Inspection: Satellite inspection technology allows spacecraft to be inspected remotely, providing a detailed picture of their condition and helping to identify areas that require maintenance or repair.

5. Automated Maintenance and Repair: Automated maintenance and repair technology enables spacecraft to be serviced and maintained remotely using robotic technology, allowing for more efficient and timely repairs and maintenance.

6. On-Orbit Assembly: On-orbit assembly technology allows for spacecraft components to be assembled remotely, eliminating the need for astronauts to travel to each craft in order to assemble components.

7. Global Satellite Communication Systems: Global satellite communication systems enable spacecraft to communicate with each other and with ground control, allowing for data and commands to be transferred quickly and accurately.

Mostak Ahamed Thank you for the answers. Both are new equipment. One new model and one old model. We have already moved on to buy the new model.

No, it is not suitable

Dear António Brandão . See the following useful link: https://mdpi-res.com/d_attachment/sustainability/sustainability-13-13268/article_deploy/sustainability-13-13268-v2.pdf?version=1638322451

Study the attached google search. David Booth

ACI report ACI 231 Report on Early-Age Cracking: Causes, Measurement, and Mitigation is available from ACI web site. Key causes include autogenous shrinkage, drying shrinkage, and subsidence cracking, in addition to any poor design and construction issues. Proper curing is critical to avoiding early age cracking. Mitigation strategies include internal curing (lightweight aggregates or superabsorbent polymers), shrinkage-reducing admixtures, and coarser cements (see the work/advocacy of Richard Burrows in the US).

Thank you for your helpful estimation and notices!

Best regards

Bernd

Language maintenance is the maintenance of a language (usually L1) despite the influence of external sociolinguistic forces (usually powerful language(s) and language shift, is a shift, transfer, replacement or language assimilation of usually L1 to L2 due mainly to the external sociolinguistic forces influencing a speech community to shift to a different language over time. This happens because speakers may perceived the new language as prestigious, stabilized, standardized over their L1 (lower-status). An example is the shift from first languages to second language(s) such as the English language.

Social network deals with the relationships contracted with others, with the community structures and properties entailed in these relationships (Milroy, 1978,1980 &1987)

· It views social networks as a means of capturing the dynamics underlying speakers’ interactional behaviours and cultures.

The fundamental assumption is that people create their communities with meaningful framework in attaining stronger relationship for solving the problems of daily life.

Personal communities are constituted by interpersonal ties of different types, strengths, and structural relationships between links (varying in nature) but a stronger link can become the anchor to the network.

Such networks have the following characteristics, they are

Where do we find some close-knit networks? In smaller communities, but also in cities, because of cultural and economical diversity, e.g. newer emigrants communities, or High-educated individuals.

Functions:

These networks have the following characteristics, they are:

Lead to weakening of a close-knit network structure -> these are prone to change, innovations and influence between groups and may lead to language shift/language transfer/language/language replacement.

Dear Vit,

We use the Dynapac LF62 in our labratories (pls. see the picture attached).

Best regards, Harald

I'm having the same problem in 2022.

Low recoveries are typically due to too low a combustion temperature but high recoveries must be a calibration issue

You need to identify first all the possible and relevant strategies for the maintenance. When the failure probability is high even if the severity is less your maintenance strategy is to detect such failures. If the failure probability is high and severity is also high, your maintenance strategy should enable predictive and preventive maintenance. Few thoughts from me. If you require more insights pl let me know exactly what you are looking for

This number is suitable for cattle comfortable temperature (generally 15 to 18℃), house feeding, light activity, no stress environment. When the temperature is below 12℃, the maintenance energy needs to increase by 1% for every 1℃ decrease. Net energy for weight gain (kj) of growing-finishing cattle = (2090+25.1W)X daily gain /1- (0.3x daily gain) [where W is body weight (kg)

Cytoplasmic male-sterility (CMS) has been used in F1 hybrid seed production in onion (Allium cepa L.). The CMS lines can be maintained by pollinating it with cytoplasmic male fertile line.

https://www.researchgate.net/publication/348161941_Male_sterility_in_onion_Allium_cepa_L_origin_origin_evolutionary_status_and_their_prospectus#:~:text=Cytoplasmic%20male%2Dsterility%20(CMS),been%20obtained%20in%20previous%20studies.

My group pioneered peptide sequencing by in source fragmentation almost 35 years ago on nESI-TOF. ESI is a metastable process. There is a process time constant associated with every tweak you make in the system. In the old days you had to tune the MS which involved things like adjusting detector threshold voltages, the push-pull voltages of the orthogonal ion beam diverter to the TOF, Einsel lens potentials, gas flows, and nozzle voltage, and x, y, z position of the nanospray head. While the service tech can now set these so you can forget it on today's MS instruments on the annual maintenance visit, back in the day we had to do this every single day on startup. Every tweak you made took about 5 min for the signal to become stable again, so it used to take up to half a morning before you could begin doing your work. You have to remember that it takes time for the ions beam to get through all the electromagnetic components inside the instrument before they get to the detector.

As Sociolinguistics focuses on the relationship between language and society, this relationship being multilayered has led to the emergence of all those subfields which connect language with the sociocultural fabric of any society. Whether one looks at cross-cultural linguistics, language and gender, dialectology, contact linguistics, multilingualism or language endangerment, all these areas fall under the domain of Sociolinguistics.

The following references were very useful for me for the creating case studies in relational databases concerning DBLC, which is very similar to SDBC: http://www.pkirs.utep.edu/cis4365/Tutorials/Database%20Design/General%20Design/Tutorial%207.00100/tutorial%207.00100.htm http://cisnet.baruch.cuny.edu/holowczak/classes/4300/week2.html http://courses.washington.edu/infosysb/class6-00-10-06.pdf http://foe.mmu.edu.my/course/ecp3076/Lec6.ppt

Orbis database, most comprehensive ownership structure up to 0.01% shareholders and subsidiaries up to beneficial ownership and Group Ultimate ownership information

Hi Samer Al Halasah

You would have to get in touch with some of the companies and see if you can request the data. I would imagine not many will be fore coming. However, if you sign a NDA and you arent going to publicise were the data has come from then they may be willing to provide you with the data. Does your University have any collaborations or partnerships with any manufacturing companies. If they have it may be easier for you to go down that route.

Best Regards

Martin

I might consider a broad approach as a first step. I would familiarize myself with the data by visually exploring the data. In my space, a graph is an important analysis tool which helps providers direction.

Thank you Dr. Bulcsu Szekely !

Great

I recommend you to use ROCK inhibitor (Y-27632; Wako) at the first day of seeding then should be removed after 24h (more than 24h has negative effect on cell growth)

If you want to, yes. Why not?

To identify the failure modes of valves, motors, switches, etc. you can read maintenance manuals of that specific system/equipment, brainstorm with experts and check out for equipment maintenance/breakdown history records. Then you can decide the criticality of that equipment and what maintenance strategy that you are going to apply (You may read more on "Reliability Centered Maintenance"). Then if the predictive maintenance strategy is justified, there are several methods/tools you can use to predict abnormalities, Ultrasound/Vibration analysis/Oil analysis/Non-destructive testing, etc.

Eg: Induction Motor

You can use ultrasound to find an abnormal condition of an induction motor at an early stage. You can use vibration analysis to predict the motor bearing condition/defects. When bearing condition got worst you can hear the noise and also then using thermography you can see the hot condition of the motor. ( You may refer to PF curve). EMD technique can be used to predict stator winding conditions in downtime.

Hola Iker Otxoa De Latorre

In case you would like to utilize Machine Learning, I think you should consider an Unsupervised method, because Supervised learning like Classification is not always practical in industrial environment due to the lack of labeled data.

One solution you can consider is to use AutoEncoder for Anomaly Detection of Time Series data.

You can refer this paper: https://doi.org/10.1016/j.egyai.2021.100065

In case you like a programming example: https://www.tensorflow.org/tutorials/generative/autoencoder#third_example_anomaly_detection

Yes, your data is Time Series, but with Deep Learning approach like AutoEncoder, your time series doesn’t always need to be equally spaced (just accumulate when machines runs).

The general idea is to collect time series data of normal state for training the AutoEncoder until it can reproduce the input with an acceptable gap (small reconstruction errors). Then you used the trained model to monitor real time data. If the trained model cannot reconstruct new data (big reconstruction errors), there is a suspicion of Anomaly.

Of course, some data preparation (e.g. normalization…) must be done when training as well as monitoring.

I am applying this method for my Trabajo Fin de Máster (an Industrial Predictive Maintenance topic) and the preliminary result is quite positive.

With this approach, in short term, you may provide quick results for factory improvement. At the same time, as I search in Google Scholar, this approach is still new (most publications in 2019 - 2021). It means there is still much room for your academic research in long term. I think you're right, Time Series modelling is mature, but not too mature for your further ideas.

Of course, it is just the way I know and there are many possible methods.

I am finalizing my Trabajo Fin de Máster using this method. You can contact me for further discussion if any.

Un saludo,

Marcos Huy Le

Hi, Pranjal Garg so first I would say you could search on Google Scholar. You should see, if the search is reduced to a minimum the question of citations. You could then do a search on Scopus and PubMed always getting the number of citations.

Trivially, if you also search on our ResearchGate portal you can find information on citations and various metrics such as interest related to that topic.

I hope I was helpful, if you need a hand in C. Elegans feel free to contact me.

Keep in touch.

Voltage regulation could be controlled by not allowing neutral point to shift by monitoring the load balance, as poor regulation would be of heavily loaded phase…

Would reduced the life consuming cost, would increased the generating and transmitting efficiency, would reduced the temporary faults, increasing reliability of power system. Short time overloading could also be increased, refer my papers on short time over loading utilizing remaining life of a day……

Ahmad Jazzar points 1 & 2 shows if you want to extract a value for total discharge in PLAXIS 2D you need to simply define a cross-section (CS).

By right clicking and defining two points on your model you will be presented with a value for total discharge. What is the case the unit?

One of my favorite authors on this topic is M.V. Ramana:

Dear Andrea:

You could realy benefit from this valuable attached book about your topic:

"Energy Indicators for Sustainable Development: Guidelines and Methodologies"

By INTERNATIONAL ATOMIC ENERGY AGENCY, VIENNA.

I hope it will be helpful...

With my best wishes...

Similar question to before, but for bearing replacements. Do people actually do this every 4 years as recommended without seeing any worrying symptoms? I've never sent a pump in for this, and I imagine this is >$1k service charge, but I also don't want a pump to shred itself because I didn't do it. Then again, if you start to get overheating and auto shutdowns in advance of something catastrophic, this could be used to indicate bearing replacement time prior to a serious problems. I've been working around turbo pumps for almost 10 years and been responsible for probably 12 turbos, and I've only ever seen a turbo shred itself once at an institution I was at, and that wasn't even my lab, and the turbo involved was comically old. Destroying a pump because of pushing maintenance intervals is a terrible outcome, but this honestly seems rare in my experience, and spending the cost of a new pump on bearing replacements every few years is also not ideal if you are quite unlikely to avoid destroying a pump. I understand the considerations are situational, e.g. if an unexpected pump failure in an industrial setting will lead to a huge daily monetary loss in revenue or productivity then skimping on pump maintenance is unwise, but if it means a couple weeks delay in an experiment and the failure is a super rare occurrence this is not such a big tradeoff.

In short, it is just another cycle or variation in marketing. "Synthetic" drugs have not "failed", and MOST were developed from "biologics" to begin with. Biologics may be a step up in potency to many homeopathic or 'herbal' cures. The production methods (live organisms) are what make them more expensive than synthesized drugs. It is an alternative, just as Vegan diets or Homeopathy are alternatives to health care concerns. They are not necessarily 'better', as each individual is unique in lifestyle, ailments, and response to disease and curative agents.

Mesenchymal stem cells tend to have a biphasic spectrum of responsiveness to inductive factors, including osteogenic factors. Therefore, if your particular preparation of MSCs has a tendency to behave in an osteogenic manner under baseline conditions, inductive factors like dexamethasone could actually inhibit this osteogenic process. Osteogenic tendencies can be gradually induced by several factors inclusing certain FBS preparations, and sustained exposure to high cell density during passage. For rat MSCs especially, culture at very low density - a good rule of thumb is have them touch no more than two other cells at the point of harvest. - this is an oldie but a goodie: Javazon et al. PMID: 11359947

Hi Muhammad, I attached the data sheet, hopefully is usefull.

Thank you for the link Mohammad Mahbubur Rahman

Indeed, Pareto's law allows prioritizing the allocation of resources, segmenting the assets that add value from those that do not. However, this tool must be embedded in a context of statistical control, due to in isolation it offers somewhat superficial conclusions. In other words, the approach at this tool must be after doing a whole design of experiments, a pilot test and a definition of the levels of randomness in the processes.

sounds like a slippery connection (belt?) between your motor and grating/slit. if possible check it first.

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