Laser Ablation-Inductively CoupledPlasma-Mass Spectroscopy (LA-ICP-MS) - Science topic
Laser Ablation-Inductively CoupledPlasma-Mass Spectroscopy (LA-ICP-MS) is an in Laser Ablation Inductively Coupled Plasma Mass Spectrometry the sample is directly analyzed by ablating with a pulsed laser beam. The created aerosols are transported into the core of inductively coupled argon plasma (ICP), which generates temperature of approximately 8000°C. The plasma in ICP-MS is used to generate ions that are then introduced to the mass analyzer. These ions are then separated and collected according to their mass to charge ratios. The constituents of an unknown sample can then be identified and measured. ICP-MS offers extremely high sensitivity to a wide range of elements.
Questions related to Laser Ablation-Inductively CoupledPlasma-Mass Spectroscopy (LA-ICP-MS)
I am interested in quantifying some trace elements in calcite through LA-ICP-MS. I am using iolite4 software. I collected the elements of interest to me, and I collected 44Ca to use it as an internal standard. Since 44Ca is not the most common isotope, should I use its percentage (2.09%) and multiply it by the total Ca presence in calcite (40%), or should I just use 40% for the value in the internal standard?
In MACS-3 standard, there is only one entry for each element, so in a tutorial that I saw, the value of 40% was used. I do not understand why.
Between TIMS and LA-ICP-MS, ICP-MS may be most easier. But in case of range of technique i.e., K-Ar, U-Th-Pb, K-Sr, etc dating which is better for use in lab?
I performed LA-ICP-MS experiment using NIST 610. I also measured the concentration of different elements on NIST 612 for quality monitoring and control puroposes. I noticed that for all elements of interest, their calculated concentrations in the NIST 612 sample was very close to the accepted standard value, with the exception of Titanium which was way higher than the accepted one. What could be the reason of this?
At the end of 2021, we studied zinc sulfide grains from one of the Pai-Khoi deposits, Polar Urals, RF, using the LA-ICP-MS method. The content of more than 20 chemical elements in more than 70 grains of sphalerite with an admixture of wurtzite from different deposit zones was studied, and their distribution patterns were revealed. An unusual micro impurity of vanadium was found, associated with submicron ingrowths of the rare mineral sulvanite and many valuable patterns related to the distribution of Ga, Ge, In and some other metals. Using a new geothermometer and the fluid inclusion method, the formation temperature of this deposit was determined. A draft of the article was written, including new data. A plan for further research has been drawn up.
In 2022, with the help of colleagues from the Czech Republic, we managed to leave EBSD maps of grains with a maximum content of V, in which it was supposed to find colusite microinclusions. The resulting maps illustrate some grains' complex and irregular zoning according to sphalerite and wurtzite. Many articles are devoted to studying the distribution of micro impurities among these two ZnS modifications. It was decided to compare the available EBSD map with the trace element distribution map, which can be done using the ICP-MS method with laser sampling. But, unfortunately, our device was broken.
It has been under renovation for eight months now.
In this regard, I would like to ask the following. Can someone from the community lend time on your equipment and map LA-ICP-MS 2-3 grains of zinc sulfide (grain size ~400-500 microns)?
We are ready to add this person to the article's co-authors or mention it in the thanks section. I am prepared to come to your organization in person if necessary. Or send samples by mail.
I hope for your help. It is painful and hard on the soul because quite interesting samples on which many works have been carried out are gathering dust on the shelf, and new results have not yet reached colleagues.
Q1: In many articles on jadeite and jadeitite(Shi 2008,CÁRDENAS-PÁRRAGA2021, Meng 2016, Abduriyim2017, et al.), scholars draw spider diagram based on trace element data and REE from LA-CIP-MS. But the number of elements in the horizontal coordinate is often different. What is the principle on which this is selected?
Q2： When some of the results of the test are below the detection limit（bdl) , or the corresponding elements are not detected (nd), how should they be reflected in the diagram?
My problem is that cassiterite measured on LA-ICP-MS is around 30Ma older than monazite from cassiterite parental granite. Monazites from one sample have wide age distribution (70Ma).
Data processing and calculation of abundances, isotopic ratios and dates were carried out off-line through the software Iolite v. 2.5, using for the dating also the Iolite-integral VizualAge data reduction scheme by Petrus & Kamber (2012), and for the trace elements determination the Trace_Elements_IS data reduction scheme.
calculated from Suzuki 2008
I am the manager of a laser ablation lab at Cornell and we have an ESI NWR193HE that was installed Aug 2020. Its only been truly operational for about a year but we are experiencing a high loss of laser energy over time. Fluences of 5-10 J/cm2 are costing more and more of the laser's energy output. At about 6 months, we were already at half of the installation energy output, now at a year we're at a quarter. The service engineer has quoted us for some very expensive optic repairs but has anyone else experienced such a high loss this quickly before?
Dear colleagues, my team and I are currently working on developing isotopic dating methods in our lab focused on dating faults and set time constraints on the post-rift tectonic events of the Brazilian passive margin. We are already working with fault-filling calcite U-Pb data, but we also have several samples of epidote veins that we would like to investigate with LA-ICP-MS. I am aware of Peverelli et al. (2020) very interesting work about U-Pb dating of fault-related epidote using allanite as both primary and secondary standards, but we are open to other suggestions of matrix-matched reference materials if you have any. We are also looking for the Tara allanite standard for that matter, so if anyone knows a quicker way to acquire it would be of great help.
Thank you for your attention and best wishes to you all!
I want to use LA-ICP-MS to measure trace elements in quartz. However, I found the laser I used cannot ablate quartz. It seems that the laser beam just passes through this mineral (See the video 1). In some situation, after several-second laser ablation, the quartz bursts (See the video 2).
The laser I used is Resolution M50 (nanosecond, wavelength: 193nm).
So, does anyone have the experience for quartz analysis by LA-ICP-MS and can give some suggestions for me?
I have ms ThermoXseries2, mostly working with sulfides and gold in it. For last two years signal for gold during ablation has become lower. No such problem with, for example, S or Fe or Ag. The same thing with solution. On tune U is lower than In. Li and Co is ok. Calibration on solution is ok, mass calibration and detector cross calibration also ok. Detector is new (2020).
Looking for the cooperation from geoscientists having laboratory access/facilities to analyze Oxygen and Sulphur isotopes in delta notation and zircon chemistry by LA-ICP-MS.
The above experimental requirements are a part of exploratory work for probing fertlity status of a newly detected porphyry style mineralization in NE Indian Precambrian shield having all basic signature of mineralization.
In the literature, it's very clear that when preparing otoliths for trace element analysis by LA-ICP-MS, people who section (cut) their otoliths subsequently polish them.
I am trying to determine if the polishing step is actually necessary, given logistical constraints in a current project that I'm participating in. Our current lab setup allows us to very accurately section otoliths and expose their core.
Cons of polishing are: (1) it's very time & labour intensive, (2) it potentially introduces surface contamination, either from the polishing surface or from other otoliths.
Pros of polishing are: (1) it evens out the otolith surface, which may be rough from the cutting process, (2) it increases the clarity of otolith microstructures (e.g. increments), (3) it makes sure the core is exposed (which we can already do using our cutting method).
What are your thoughts on this?
Does anyone has experience dating scheelite from hydrothermal gold deposit using the following two isotopic systems (U-Pb by LA-ICP-MS and Sm-Nd by TIMS)? Any advice concerning the settings to use with the laser (using the NIST 612 glass standard as a primary standard) and the dissolution technics for the TIMS?
Thank you very much,
There are several destructive and nondestructive microanalytical analysis methods, but particularly I wonder about EPMA and LA-ICP-MS. The main theme of my research is dating, tracing elements in different geological environments, mapping them in melts, fluid inclusions, minerals and understanding environmental parameters such as temperature, oxygen fugacity, the water content of magma etc.
I will be collecting carbonatite samples for LA ICP MS. They will be ground in order to handpick zircon crystals for U Pb geochronology. I want to get 100 zircon grains. What sample weight should I take?
I'm trying to find the partition coefficient for REE in fluorite. There have been a few papers which say they have a Kd value but do not specifically state what it is in the paper. When I go through their references, I can't seem to find the value in those papers either.
I have fluorite from 2 districts and I have done LA-ICP-MS analysis on the fluorite. It is the the goal to try to deduce the REE concentration in the fluid based on the concentration in the fluorite. Does anyone have a good reference on the partition coefficient? I appreciate it.
I commonly find that detrital zircon samples analysed by LA-ICP-MS display discordia arrays, in Wetherill space, that plot toward the origin. This implies some form of recent lead loss - a topic most recently addressed by Pidgeon et al 2017 and Andersen et al 2019. In TW space, these analyses also imply recent lead loss. I typically observe these effects in older zircons, typically older than c. 1.5 Ga (arbitrary age). Could this be because older zircons are typically more vulnerable to lead loss? I do not think this is the case. Instead, I think it is simply because discordia arrays are exaggerated for older upper intercept ages and therefore more noticeable. A supporting question to my main question, then, is what does lead contamination during analysis look like in comparison to recent lead loss in Wetherill and TW space, assuming such contamination is allowed to pass through the data reduction process?
I study contact and regional metamorphism of Dizi series, Great Caucasus, Georgia. I have a problem only with analytical part of my work. And It would be great to share knowledge and experience with someone who works in metamorphism.
I am a sedimentologist interested in sediment provenance. My department bought a LA-ICPMS and I want to use it for detrital zircon analysis.
However, since LA-ICPMS is a destructive method, I need lots of standard to measure zircon ages. I looked for commercial standards, and it seems that it is not easy to buy it. I can get some standards - for example, 91500 zircon - but it is not certainly enough.
Does anyone can give me an idea to get standards?
Does anyone could tell me which kind of features should I consider between the techniques Laser-Induced Breakdown Spectroscopy and Laser Ablation Inductively Coupled Plasma Mass Spectrometry to buy an instrument that will be used in geological samples for a geochemistry fingerprint focused research?
Both use Laser Ablation for particle generation so the sample preparation step is minimal but I would like to know about the instrument and maintance costs (if somebody has a shallow idea about it), the detection limits and the advantages that have one over the other.
I deeply appreciate your help in advance.
I would like to analyse the chemical composition of glasses that I study. One available method would be LA-ICP-MS (laser ablation inductive coupled plasma mass spectroscopy).
Unfortunately, the standard reference material I have available (NIST610) only contains P2O5 up to ~300 ppm and Al2O3 up to ~ 1 mol%. In order to properly calibrate the instrument for my measurement I would need one or several standard materials that contain at least ~10 mol% (~15 wt%) P2O5 and ~25 mol% (~35 wt%) Al2O3.
I didn't find suitable reference materials in the NIST catalogue. Does anyone by chance work a lot with phosphate glasses and knows a suitable reference material?
I have learned that baddeleyite occurs in ultramafic and mafic rocks and is used as an alternative to zircon to date these rocks precisely (using U-Pb TIMS/SIMS/LA-ICP-MS/EPMA techniques). My questions are:
(1) What are the optical properties of baddeleyite (ZrO2) which can be used to identify it using a petrological microscope?
(2) How it can be distinguished from zircon and other similar minerals?
Would be interested what is your experience/preference for epoxy resin for embeding mineral separates. Especially with the adhesion of very small grains (below 100 micron) in the resin during polishing. I have used 3 resins in the past:
Buehler Epoxicure - smells like a hell, rather soft, viscous when mixed, easily etched by acetone
Struers Epofix - hard, less viscous
Araldite 2020 - hard, least viscous of all
The reason Im asking is the recent experience with some very small zircon grains jumping off the Araldite resin during polishing and lasering. I do not think this was happening with Epofix resin before. Any of you have any experience? It would be greatly appreciated.
I am trying to avoid using NIST glasses because of matrix matching errors. I am hoping to analyze shales and limestones. I have a ton of ICP-MS solution standards and some money to purchase reference materials if needed.
I am being vague because even if your method doesn't directly apply to my work, I'm sure it will be tangentially helpful.
I've been looking for studies applying LA-MC-ICPMS for in situ 230Th–232Th–234U–238U analysis (ie, for 230Th excess measurement) on ferromanganese crusts, and have come up empty. Can anyone help? I want to be thorough. If you think they don't exist, that's also useful. Thanks in advance!
Is it feasible to use the trace element data extracted from LA- ICP MS for the foreland basin sedimentary rocks; Sandstone?? I have already extracted the U-Pb ages but unknown about the uses of the element data available from the ICP MS ) e.g.; Si29, Ti49, Y89,Zr90,Nb93,La139,Ce140,Pr141,Nd146,Sm147,Eu153,Gd157 and so on). If you have some papers regarding this type of study then please do suggest me
I'd like to measure laser ablation plasma using LP(Langmuir Probe).
Then, the LP's theory is based on Maxwell distribution.
However, some kind of laser ablation plasmas are not the distribution.
I have seen some papers about measurement of the parameters of the plasma using LP.
I'm wondering about the correctness of the results of these papers.
Please advise for this question.
(and please introduce any reference documents if you know)
We would like to pick zircons from a fine-grained sedimentary rock which has much amount of pyrite. Without any chemical treatment, we want to get rid of pyrite. I checked their densities and magnetic susceptibilities, but they are not so different. What do you recommend me? Are there some heavy liquids or other physical process to seperate pyrite?
Is it possible to differentiate human bones of animal bones, by chemical analyses (elemental or isotopic) ? Is that possible by LA-ICP-MS or LA-MC-ICP-MS
I would like to conduct compositional analyisis on a sample of medieval coins (alloy of silver with a majority of base metal content). It is known that the quantity of silver in these coins decreased over time; compositional analysis will help determine accurately the actual silver variations and thus, the relative chronology already proposed for these coins. I intend to conduct X-ray fluorescence analysis (full area scan). I would like to make sure that possible surface enrichment of coins (sometimes medieval coins had enriched silver surface) would not compromise the reliability of data. Could anybody give me some more information about XRF analysis (full area scan) ? Thank you very much
I have done La-ICP-MS on the zircon and ICP-MC analyses on the whole rock. Can I use Ce concentration in the whole rock Instead of concentration of the element in the melt?
I had ICP-OES process on Cd accumulation (In %65 Merck HNO3). But my results are in mg/kg. I guess 1 mg/kg = 1 ppm, so I can use same value with ppm unit. Am I thinking right or there is a tricky point that I miss?
I have a 208 V ICP-OES from US but the power supply in my country is 220V. I need to use the equipment for my trace metal analysis while working on incineration waste and I do not have the user's guide.
Hello, Everyone. As the title of this question, I hope someone would provide more detailed indicators to help me make a decision when I process my raw data. Thanks a lot!
Please explain the difference between the spot size and the crater diameter and how to find them? the ablation threshold range of steels machined by femtosecond laser?
- 'Im working on ICP MS perkin elmer Elan 9000 series. I am getting very high intensities. For the past two days I m facing the problem. Not able to rectify the problem can anyone suggest a solution
I have been through the manual of UranOS software but very limited information is provided over there. I am able process the data and getting some dates also, but the error is quite high (+/-200 Ma). I don't know where I am doing mistakes, but I have followed all what's there in manual. Is there any detailed manual available or had somebody worked with this software? Please help.
I want to generate data of zircons by LA-ICP-MS. I have about ten plutons from a Precambrian sield of NE Indiia, having Supercontinental partnership with Columbia and Pan-African assemblies, whose data are needed in a metallogenc appraisal. There is practically no data on geochronology and crustal history of development. May I have the academic partnership to grow through joint publications? I seek answer from like minded workers who can provide me the facility. This will be trusted one with great honour.
Can Any researcher help me?
Is the LA-ICP/MS technique suitable for the quantitative or semiquantitative determination of elements and their isotopes or is it only useful to obtain element and isotopes ratios ?
One of the limitations is the lack of good standard references (glasses) for most of the environmental and geological samples
Samples of interest are: volcanic tephra, sediments, soils, dust, aerosols, potable water, waste water, and so.
Does somebody have experience with it?
Does anyone use hydrogen during the laser ablation in hellium atmosphere for increasing sensivity and what rough ratio of hellium to hydrogen flow is more suitable?
I am going to be picking zircons for the first time soon. I have read a lot of literature related to single-zircon LA-ICPMS work for provenance studies. I am concerned about introducing bias when picking, for example: I seem to be able to spot euhedral zircons better than I do rounded ones. Ideally, I would like to pick the "optimal number" (per sample) for a provenance study (Vermeesch, 2004) but how then do you weight the different types of grains within the sample? A modal abundance of different types of zircon grain within the sample could be used to determine what ratio of round to euhedral (or whatever) would be required, but this seems like it can be difficult to estimate, particularly if you do not have a high purity zircon concentrate. I know this may seem trivial to some, but the more I read, the more concerned I become! Any advice would be much appreciated.
I need to make a comparison study where I'll need to remove the zircon grains from the mounting after the analysis so I can to some stuff and then mount right back, but the epoxi resin we use is virtually inssoluble and I'm afraid the Entellan might have lead or some other stuff that contaminates my analysis.
Is there any material that I can use that provides easy removal of the grains?
I am currently trying to measure chromium between 10-20 nmol/L in whole blood by ICP-MS (octopole) but am having problems with sensitivity at the lower end (>20 nmol/L no problems). Can anyone offer any advice or recommend any papers which may help?
Has anyone else conducting U-Pb LA ICP-MS on calcite, zircon or other minerals encountered variable 238U/206Pb ratios with relatively invariant 207Pb/206Pb ratios?
I've analysed a number of other speleothems from other caves in the UK, Canada and Australia, and the data produce proper isochrons, but all of the samples from Borneo have produced data like this and I have no idea what's causing it. The machine setup was operating within normal parameters and all standard analyses (91500, NIST614 and an "in-house" carbonate standard) behave as normal.
If anyone can suggest any possible causes, or recommend any papers that have dealt with or encountered this, that would be a great help.
I've obtained data by LA-ICP-MS, and now I'm looking for data to compare my results, and whole process of analyse.
I'm trying to understand the post-translational modifications of a certain protein at different conditions. The protein can be immunoprecipitated from mouse tissues.
Is there a proteomic (or other type) techniques available out there that can be used to identify and/or measure the level of ALL, or common post-translational modifications (e.g acetylation, ubiquitination, oxidation, phosphorylation, glycation, etc) of a protein under different treatment conditions in a high throughput manner?
I've asked and I was told that neither 2D gels nor mass spectroscopy can be used for this purpose.
I'll really appreciate any suggestions or ideas.