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The universal dihydrouridine (D) epitranscriptomic mark results from a reduction of uridine by the Dus family of NADPH-dependent reductases and is typically found within the eponym D-loop of tRNAs. Despite its apparent simplicity, D is structurally unique, with the potential to deeply affect the RNA backbone and many, if not all, RNA-connected proc...
Conference Paper
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L'ultimo Posto tra i Monti della Tolfa i Monti Sabatini, ed il Lago di Bracciano, al centro di un'area ricca di giacimenti minerari (zolfo, manganese e marcasite) e punti di emissione di gas ed acque termali, Monterano. fu un importante centro urbano in età etrusca, la cui floridezza è documentata soprattutto dalle necropoli rupestri circostanti. D...
Article
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Neural collapse is an emergent phenomenon in deep learning that was recently discovered by Papyan, Han and Donoho. We propose a simple unconstrained features model in which neural collapse also emerges empirically. By studying this model, we provide some explanation for the emergence of neural collapse in terms of the landscape of empirical risk.
Article
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The neoadjuvant and adjuvant anti-PD-1/PD-L1 treatment has been increasingly noticed. To summarize the global landscape of these clinical trials will provide essential data for all the stakeholders of drug development. Based on the Trialtrove database, a total of 668 clinical trials initiated by the end of 2020 were retrospectively analyzed. We fou...
Article
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Although various strategies have been included in nanotoxicity evaluation, epitranscriptomics has rarely been integrated into this field. In this proof-of-concept study, N6-methyladenosine (m ⁶ A) changes of mRNA in HEK293T cells induced by three bovine serum albumin (BSA)-templated Au, CuS and Gd 2 O 3 nanoparticles are systematically explored, an...
Article
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Currently, most CNS tumors require tissue sampling to discern their molecular/genomic landscape. However, growing research has shown the powerful role imaging can play in non-invasively and accurately detecting the molecular signature of these tumors. The overarching theme of this review article is to provide neuroradiologists and neurooncologists...
Article
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The interactions between emotion and attention are complex due to the multifaceted nature of attention. Adding to this complexity, the COVID-19 pandemic has altered the emotional landscape, broadly heightening health and financial concerns. Can the heightened concerns about COVID-19 impair one or more of the components of attention? To explore the...
Poster
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L’évolution enregistrée par la notion de patrimoine industriel ces dernières années implique un réexamen des approches qui vont traditionnellement vers la vision de la relique du bâtiment industriel ou vers l’homogénéité qui ne distingue pas entre le nouveau et l’ancien. D’autres prônent un patrimoine modernisé où la partie ancienne est différencié...
Article
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The article introduces the new gradient descent/ascent algorithm for independent component analysis for complex valued data (cICA). This algorithm uses toral decomposition of skew-Hermitian gradient matrix and very simple and computationally inexpensive method of projection based on Lie structure of optimization landscape. Toral decomposition is th...
Article
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Z-scheme photocatalysts have recently received tremendous attention because of their extraordinary light harvesting and utilization ability, spatially-separated reductive and oxidative active sites, and strong redox capacity. This review depicts a panorama of the latest discoveries and developments of Z-scheme photocatalysts for solar-driven fuel p...
Article
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In this paper, we analyze the landscape of the true loss of neural networks with one hidden layer and ReLU, leaky ReLU, or quadratic activation. In all three cases, we provide a complete classification of the critical points in the case where the target function is affine and one-dimensional. In particular, we show that there exist no local maxima...
Chapter
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A partir del caso de Detroit se realiza una reflexión sobre el nacimiento del Landscape Urbanism, que analiza las condiciones espaciales, sociales y económicas que reclamaron el surgir de un enfoque distinto respecto a los proceso de regeneración arquitectónica y urbana existentes. Este capítulo se dirige hacia las potencialidades del paisaje como...
Conference Paper
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Automated vehicles should improve both traffic safety and user experience. While novel behavior patterns such as platooning become feasible to reduce fuel usage, such time-and fuel-reducing behavior at intersections can be perceived as unsafe and possibly disconcert users. Therefore, we designed and implemented nine feedback strategies for a simula...
Article
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Deleterious variants in DNA damage repair (DDR) system can cause genome instability and increase cancer risk. In this study, we analyzed the deleterious variants in DDR system in 16 ethnic human populations. From the genetic variants in 169 DDR genes involved in nine DDR pathways collected from 158,612 individuals of different ethnic background, we...
Article
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Non-canonical forms of DNA are attracting increasing interest for applications in nanotechnology. It is frequently convenient to characterize DNA molecules using a label-free approach such as ultraviolet absorption spectroscopy. In this paper we present the results of our investigation into the use of this technique to probe the folding of quadrupl...
Article
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En el presente trabajo se reflexiona el paisaje desde la geografía cultural, la cual reconoce que la complejidad natural y cultural del paisaje son riquezas invaluables. Estas riquezas invaluables, nombradas como patrimonio en la gestión cultural, se llaman aquí herencias territoriales (HT) con la intención de tener una mirada más democrática en su...
Article
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In this article, the author provides synopses of the factors that have finally propelled health‐care education and practice to join, at times reluctantly, the overarching digital transformative process that has been swept other industries over the last few decades. The key contributors and driving forces that have energized the entry of health‐care...
Chapter
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Las ciudades son espacios sociales que definen las oportunidades de desarrollo de sus habitantes a partir de su localización; por ello, es necesario conocer los patrones de distribución del perfil epidemiológico de la población adulta mayor. Este trabajo presenta el panorama epidemiológico de la población adulta mayor, considerando los datos de mor...
Article
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Identification of urban growth patterns is essential to better understand urbanization and its eco-environmental consequences. Landscape indices, such as the simple urban growth index (S) and the landscape expansion index (LEI), are commonly used to identify urban growth patterns, but most of them are unable or not robust enough to recognize multi-...
Article
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This study provides a systematic review of the literature on innovation research (IR) over the past two decades. We used data-driven approaches integrating network and natural language processing techniques on 41 innovation core and ancillary journals to characterize the IR landscape. Contrary to previous efforts, we explored knowledge in the whole...
Article
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Advancements in artificial intelligence (AI) technologies are rapidly changing the competitive landscape. In the search for an appropriate strategic response, firms are currently engaging in a large variety of AI projects. However, recent studies suggest that many companies are falling short in creating tangible business value through AI. As the cu...
Article
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This paper assesses the remote sensing datasets of biomass carbon on the agricultural landscape and their decadal change dynamics due to variation in tree cover dominance using geospatial technology in India. Remote sensing data showed that in the year 2000, 16.9% of all agricultural land (28.02 million hectares) in India had agroforestry land (at...
Conference Paper
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Contemporary quantum algorithms, being efficient theoretically, fail to run on real QPUs. One reason for these failures is the algorithm's probabilistic nature, which is amplified by imperfections in hardware implementation. Grover search is such a probabilistic method, which enables other methods in quantum optimization and machine learning. In th...
Article
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Forest structure and natural regeneration of mountain pine (Podocarpus parlatorei Pilg.) populations in the department of Santa Cruz, Bolivia. The mountain pine (Podocarpus parlatorei Pilg.) is endemic to the southern montane forests, historically over-exploited for timber purposes and currently is in danger of extinction. In Bolivia, also presents...
Article
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Key message Long-read sequencing technologies are revolutionizing the sequencing and analysis of plant and pathogen genomes and transcriptomes, as well as contributing to emerging areas of interest in plant-pathogen interactions, disease management techniques, and the introduction of new plant varieties or cultivars. Abstract Long-read sequencing...
Chapter
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The use of learning analytics (LA) is growing in popularity. In this chapter, we discuss how this trend has reshaped the landscape of STEM education in terms of data collection, analysis, and interpretation. We first synthesize the use of learning analytics in STEM contexts with the primary aim of understanding how and in what ways learning analyti...
Chapter
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O objetivo deste capítulo é fazer um rápido balanço da atuação do Banco do Nordeste do Brasil (BNB) no Semiárido rural, destacando os aspectos que marcaram sua trajetória de 1952 a 2022, as características atuais da região, com foco no desempenho das operações de financiamento realizadas no período recente. Além disso, apresentam-se alguns desafios...
Conference Paper
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In this paper, we present a performative exercise aimed at revisiting, from Latin American “Southern” perspectives, two seminal articles in Participatory Design (PD): “Co-creation and the new landscapes of design” by Sanders & Stappers, and “Participation in Design Things” by Ehn. The goal is to turn peer review into a critical tool to inform estab...
Article
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Despite advances in technology that have eliminated or drastically reduced the impact of some traditional media in the US society, television has largely adapted from a small selection of traditional networks like ABC, CBS, and NBC to hun- dreds of cable networks and online streaming platforms, including Netflix and Hulu. The objective of this stud...
Article
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In reality, library managers have no other option but to embrace innovation which transcends a novel product, process or service. Failure to do so is tantamount to result in a slow demise of libraries in this fast changing information landscape. Innovation does not always have to be big hypes, shiny new things, technology-driven or necessitating a...
Article
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In our everyday experience, life, environment, and nature are connected and we tend to confuse the value we assign to them. One way around this issue is to analyze our intuitions on the terraformation of other planets such as Mars. In this way, we are forced to consider whether the original abiotic nature has a value of some kind regardless of its...
Article
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Over the past few years, the wild population of Chrysolophus spp. has decreased remarkably. Habitat fragmentation is a significant cause for this serious threat to the survival of Chrysolophus spp. population. In order to further understand the distribution of potentially suitable habitats of Chrysolophus spp., we used the maximum entropy model to...
Article
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A finales de septiembre de 1935 se celebró en Madrid el décimo congreso internacional de historia de la medicina auspiciado por la homónima sociedad internacional, constituida en 1920 para explorar las relaciones entre la historia y la medicina y otras ciencias conexas como la farmacia, la veterinaria y la odontología. En este artículo se analiza l...
Article
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ABSTRACT.—Within the Great Plains region of North America, oxbow wetlands were lost as streams were channelized and straightened to allow for agricultural use of the landscape. Topeka Shiner, which rely on these oxbow wetlands, have declined in abundance, currently occupy 20% of their historical geographic range, and are now an endangered species....
Article
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Adaptive designs are a class of methods for improving efficiency and patient benefit of clinical trials. Although their use has increased in recent years, research suggests they are not used in many situations where they have potential to bring benefit. One barrier to their more widespread use is a lack of understanding about how the choice to use...
Article
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The lack of georeferencing in geospatial datasets hinders the accomplishment of scientific studies that rely on accurate data. This is particularly concerning in the field of health sciences, where georeferenced data could lead to scientific results of great relevance to society. The Brazilian health systems, especially those for Notifiable Disease...
Article
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Globalization has changed the landscape of higher education. The purpose of this study is to enhance understanding of how higher education leaders are engaging emerging questions about successful leadership, particularly when it comes to international student populations in times of crisis. Guided by the Intercultural Leadership framework, this com...
Article
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Containers have evolved to support microservice architecture as a low-cost alternative to virtual machines. Containers are increasingly prevalent in the virtualization landscape because of better working; containers can bear considerably less overhead than the conventional hypervisor-based component virtual machines. However, containers directly co...
Article
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El aumento en el número de enfermedades emergentes ha tenido consecuencias a nivel mundial en términos de salud, economía, seguridad pública y seguridad sanitaria. A pesar de la importancia que se les da a los agentes que causan dichas enfermedades, es importante no olvidar aquellos patógenos que han estado presentes en las poblaciones humanas y qu...
Article
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El presente trabajo de investigación, partiendo del nuevo concepto de Drogas de Consumo Actual, aportado por el autor en entregas anteriores, da salida a muchas peculiaridades de este grupo de drogas que circulan en la actualidad en todo el mundo, llamando poderosamente la atención, como entre los más consumidos aparecen los cannabinoides herbáceos...
Article
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In this paper, we try to understand what considerations and possible sources of inspiration Desargues used to formulate his concepts of involution and transversal, and to state the related theorems that are at the basis of his Brouillon project. To this end, we trace some clues which are found scattered throughout his works, we connect them togethe...
Article
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Review of "Conservation Landscapes and Human Well-Being" edited by S. Krishnan, S. Devy, and N. Mohanty
Preprint
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Apart from the business of education, investing is the magical power of computing. The use of digital technology in teaching paradigms has been explored since the last century. The widespread incorporation of artificial intelligence is beginning to reshape the educational landscape. This analysis can discuss AI methods in virtual classrooms as well...
Preprint
Full-text available
Apart from the business of education, investing is the magical power of computing. The use of digital technology in teaching paradigms has been explored since the last century. The widespread incorporation of artificial intelligence is beginning to reshape the educational landscape. This analysis can discuss AI methods in virtual classrooms as well...
Book
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From last two to three decades, we are facing lots of infectious diseases and pandemic. It reveals that we are forgetting our traditional food, medicine and practices. People globally were consuming their food as per climates, seasons and landscapes, but due to urbanization adopting junk and unsuitable foods. The metallic life also leading to p...
Preprint
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Die Unermesslichkeit der Natur und die Unwiderstehlichkeit ihrer Macht auf der einen Seite, die geistige Überlegenheit des Menschen auf der anderen Seite-genau dieses Verhältnis ist es, das man in Friedrichs Bildern immer wieder dargestellt finden kann. Diese Darstellung gelingt ihm mittels einer Analogie, über die "unbedeutende Kleinigkeit" der in...
Presentation
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Hue City Urban Landscape Development Khanh Tran Ethem Kasap
Research Proposal
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Vivimos en una época de fuertes cambios y dentro de la gran incertidumbre, queda claro que existen retos muy trascendentes por venir. Uno de estos es lo que conocemos como calentamiento global, acompañado por los severos fenómenos atmosféricos que cada temporada nos sorprenden por sus comportamientos anómalos. Parece ser que el territorio, con o si...
Preprint
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While we cannot deny the exponential growth of Pentecostalism around the world, and its robust contribution to our overall understanding of the nature and power of the Holy Spirit, the theological and biblical roots of discipleship in light of the Pentecostal tradition need to be further explored. Beginning with the work of the Holy Spirit in the p...
Article
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With the growing challenges brought by Artificial Intelligence (AI)'s rapid development, multiple global AI governance initiatives have been developed to set up AI norms and standards. With China's open ambition to be an AI superpower in 2030, China is keen to play a leadership role in nascent global AI governance regimes. This article argues that...
Article
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The latitudinal diversity gradient (LDG) is one of the most recognized global patterns of species richness exhibited across a wide range of taxa. Numerous hypotheses have been proposed in the past two centuries to explain LDG, but rigorous tests of the drivers of LDGs have been limited by a lack of high-quality global species richness data. Here we...
Preprint
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Land conversion and the resulting contact between domesticated and wild species has arguably been the single largest contributor to the emergence of novel epizootic and zoonotic diseases in the past century. An unintended consequence of these interactions is zoonotic or epizootic disease spillovers from wild species to humans and their domesticates...
Article
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Internationalisation is now a prominent feature of the higher education landscape, with many institutions integrating international, intercultural and global dimensions inside and outside the classroom. In this paper, I examine the long-term outcomes of international faculty mobility on individual pathways at home institutions framed within the con...
Article
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Immunotherapy, based on immune checkpoint inhibitors targeting the Programmed cell death ligand 1 (PD-L1) and/or Programmed Death Receptor 1 (PD-1), has substantially improved the outcomes of patients with various cancers. However, only ~30% of patients benefit from immune checkpoint inhibitors. Tumor PD-L1 expression, assessed by immunohistochemis...
Preprint
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The education industry is also leveraging artificial intelligence magical power. Uses of digital technologies in pedagogical paradigms are being observed from the last century. The widespread involvement of artificial intelligence starts reshaping the educational landscape. This research will discuss AI approaches in virtual class rooms along with...
Poster
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Advances in™ Beta-Thalassemia: The Evolving Therapeutic Landscape
Article
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We show that the local density of states (LDOS) of a wide class of tight-binding models has a weak body-order expansion. Specifically, we prove that the resulting body-order expansion for analytic observables such as the electron density or the energy has an exponential rate of convergence both at finite Fermi-temperature as well as for insulators...
Preprint
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Apart from the business of education, investing is the magical power of computing. The use of digital technology in teaching paradigms has been explored since the last century. The widespread incorporation of artificial intelligence is beginning to reshape the educational landscape. This analysis can discuss AI methods in virtual classrooms as well...
Presentation
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The presentation makes a comparative study between "Jana Gana Mana," the National Anthem of India penned by Rabindranath Tagore, and "Subh Sukh Chain," the National Anthem of the Azad Hind Government led by Netaji Subhas Chandra Bose, penned by Abid Hassan Safrani. It compares the two songs, where the latter happens to have been adapted from the fo...
Conference Paper
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В результате деятельности предприятий по добыче калийно-магниевых солей активируются процессы техногенного галогенеза, что приводит к изменению микробиологического разнообразия и химических свойств почв пойменных ландшафтов. Для солончака вторичного характерно сильное засоление и бактерии, обитающие в морских и высокоминерализованных средах. As a...
Article
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This article looks at how homeland politics have shaped the perceptions of the homeland and host countries among the Oromo diaspora community. Unfavorable political conditions in Ethiopia have encouraged ethnic Oromo living in North American diaspora communities to construct alternative physical and social landscapes that evoke feelings of nostalgi...
Article
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La profunda y prolongada experiencia de desarrollo capitalista neoliberal chilena produce un cambio drástico en la estructura social, así como en las modalidades de explotación, lo que conduce a nuevos patrones de conflicto que se expresan en forma gravitante en la revuelta popular reciente. Este panorama se acompaña de profundos cambios en la cult...
Cover Page
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PRESENTED TO Kailash CAFE 2.0: Sharing knowledge of a sacred landscape
Article
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In Mexico, to effectively conserve the marine ecosocial legacy of approximately 3,149,920 km2, there are intersecretarial work groups of more than 11 federal secretariats and several national universities. Protecting the natural landscapes of Mexico has never been an easy task, but now international commitments they make it become a national priori...
Article
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The geography and geopolitics of Turkistan are subjects of considerable interest. In the present geopolitical landscape of Inner Asia and Central Asia, it assumes new significance. The present study represents the cultural (ethnic) and political geography of Turkistan. Besides taking stock of ethnicity and geography, this research also evaluates th...
Article
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This is an enlarged and updated version of the article that was titled "C H Waddington: Canalisation and Genetic Assimilation", which had appeared in Resonance vol. 15, no. 6, p.503-513, 2010. The older article is also available on Research Gate. It is now superseded by this one. The present article includes added material on Waddington's idea of t...
Preprint
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This research paper examined the dilemma of recruitment and retention of United States criminal justice agencies. The dynamic and ever-changing landscape of societal conditions and legal interpretations may challenge organizational hiring based on negative perceptions from controversial cases in the national spotlight. Additionally, this paper will...
Article
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Despite decades of crime decline, police surveillance has continued to expand through a range of tactics oriented towards policing social disadvantage. Yet, despite attention to the linkages between residential inequality and policing, few studies have accounted for two intertwined structural developments since the turn of the 21st century: (1) the...
Article
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This research aims to evaluate the sustainability of urban strategies in Skikda, a prehistoric, ancient, and Mediterranean port city of northeastern Algeria, known as by the Punic name Russicade. The port city of Skikda shows a diverse landscape of heritage sites and the industrial reality of a city, rich by its under-exploited cultural and tourist...
Article
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Este artículo ofrece un panorama general de la obra de Lawrence Stenhouse cuando se cumplen cuarenta años de su muerte. El texto identifica la dimensión filosófica, disciplinar, pedagógica e investigadora que se hallan en el corazón de su modelo de desarrollo profesional y curricular, y después las analiza en las diferentes secciones. Sin perder de...
Conference Paper
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In crisis situations access to information is key to reduce uncertainty and enable effective decision making. With the advent of modern information technologies there is an abundance of possibilities to obtain, process, and share information. The number of actors that can potentially provide information has grown concomitantly. The challenge theref...
Research
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Infográfico da série microrganismos. Este é o primeiro material de uma sequência abordando os microrganismos na produção cervejeira. Apresenta-se um panorama sobre os microrganismos envolvidos na produção, um pouco de sua história e Biologia, assim como se introduz alguns dos contaminantes. Material produzido no contexto do projeto de extensão Cerv...