Knee - Science topic

What types of physiotherapy techniques or therapeutic exercises are the best for a grade I or grade II injury of the medial collateral ligament of the knee?

It is evident that males are more fatigable during submaximal knee extensions. Has there been any studies that used a repeated knee extension protocol that showed similar fatigability between the sexes? Perhaps, there is a certain contraction speed or relative workload level that elicits comparable fatigability?

I am looking for dynamic knee extensions, but perhaps I can get some insights from isometric ones as well.

He presented with severe Varus and Posterior instability of left knee following previous ORIF 10 years ago.

Linguistic or conceptual body-part metaphors relate not only to Heads, Shoulders, Knees, and Toes, Knees, but also to Eyes, Ears, Mouth and Nose and other human body parts. Here are a few English metaphors related to “head”: head of lettuce, head of a company, head over heels in love, head Start, headers & footers, and headlights. Check out the attached PowerPoint about Body Part Metaphors, and then discuss body-part metaphors in English and other languages.

I am trying to simulate the knee joint and I have a concentrated force applied on the femoral part of the model, the model also has a kinematic constraint that allows for the femur to flex and extend ie displacement boundary condition and the tibia part is fixed. the aim is to include the anterior-posterior motion of the tibia as well

The load is time based as well as the displacements. when I run the simulation, with the required load the stress generated is the same as when 4x the initial load is applied. How can I fix this?

Please find attached the cae file for this model

For VAS score, WOMAC overall and individual component scores, KOOS and individual component scores, Lysholm score, and MOCART score

Give your inputs with references

In view of standardizing the preparation and therapeutic protocols utilized in BM-MSC therapy for OA Knee, I am looking forward to the variables to be considered.

Share your experience of dealing any of such cases of the hip

In my last research, I investigate whether patients with musculoskeletal disorders had increased susceptibility to SARS-CoV2 infection or developed more severe forms of COVID-19; as well as whether COVID-19 affected the underlying disease.

Results showed that the frequency of COVID-19 was low and statistically nonsignificant, but that led to a worsening of the underlying disease.

What are your clinical impressions, ie do you have similar research results?

Hello,

I am working on machine learning algorithms using EMG and IMU (Inputs) to map joint angles (outputs). I have used RMSE to evaluate model performance because RMSE penalizes outliers more heavily compared to MAE.

However, I am also curious if there are metrics to determine the performance of the predicted slopes (flexion vs. extension). For example, if a user is performing knee flexion, then the predicted slope should follow the same direction as knee flexion. Conversely, if the predicted slope was in the opposite direction of knee flexion by incorrectly predicting knee extension, how would we 'penalize' this prediction? In this case, should I use a binary classifier (flexion/extension) and plot a Receiver Operator Characteristic (ROC) Curve?

Radiologically more severe knee osteoarthritis of the same patient is showing nearly noraml range of motion than with the less severe one

Hello,

I am conducting a research and for that I am looking for an answer of how many mitochondria per cell and how many cell per tissue in a different type of human body parts (e.g. Knee, Shoulder, Head etc). I would really appreciate If anybody can refer me the right experimental or computational research article.

Thank you in advance.

Please suggest..

Hello everyone

Please help me to find the normal values for knee extension in kg, I want to analyze the values of my study sample. For that purpose, I want the normal values as a reference

Thanks in advance

I have developed ideas and concepts by which we can change the paradigm of OA to Cartilage attrition arthropathy, to facilitate a change in thinking, so that arthritis in the knee can be regarded as a condition that can and should be halted rather than being an inexorably progressive condition awaiting knee replacement.

Hello, I am a student, and I am trying to perform a fatigue analysis on Ansys. This is for a knee replacement joint. Usually joint spacers are made of UHMWPE. This is my first time doing this analysis. Every time I try to run the simulation, there is an error that asks me to define the S-N curve. However, no matter how hard I research, I am not able to find a curve that compares the alternating stress vs the cycles. I don't have a background with materials so I am not really sure where I could find this curve.

Is there any way to classify Knee OA into mild, moderate, and severe on the basis of just clinical examination? I have no record of radiological investigation of patients. Actually, patients were referred from the ortho department. I have the WOMAC score of all patients. How to classify the patients into the mild, moderate, and severe categories depending on WOMAC score? are there any cut-off values for the WOMAC score for each category?

In knee and shoulder surgery minimal invasive procerures have alreday proven their advantages for patients. Mainly the quick recovery. What about minimal invasive lumbar spine fixation? I hear for many surgeons that the treated patients suffer more pain than the ones treated in open way....

Hello All

I want to evaluate the usability of new AFO for patients with knee osteoarthritis. There are several questionnaire for "usability evaluation of orthoses" but unfortunately there is no exclusively one for AFO as well as in Persian version.

How can I classify knee osteoarthritis into mild, moderate, and severe on the basis of WOMAC score?

Please guide me

What makes periprosthetic ankle infections different than the knee or are they? Size of joint? Vascularity in the ankle joint? Talus perfusion being much less than the femur or tibia? Really looking forward to your opinions and experiences.

The problem is this: there is model of robot, created in Simscape. And knee of this robot is made of "pin-slot-joint", which allows one transnational and one rotational degree of freedom. In transnational motion, it is imposed the stiffness and damping factor, which gives influence also to rotational torque. My aim is to write optimization or control algorithm in such a way that this algorithm should provide such stiffness(in linear direction), which will reduce the rotational torque. By the way, rotational reference motion of knee is provided in advance(as input), and appropriate torque is computed inside of the joint by inverse dynamics. But to create such algorithm, I have no deep information about block dynamics, because block is provided by simscape, and the source code and other information is hidden. By having signals of input stiffness, input motion, and output torque, I need to optimize the torque.  I will be truly grateful if you suggest me something. (I tried to obtain equation, by using my knowledge in mechanics, but there are lots of details are needed such as the mass of the joint actuator, it's radius, the length of the spring and etc. AND I HAVE NO THIS INFORMATION.) If you suggest me something, I will be truly grateful.

I am currently planning to construct a meta-analysis on a supplement for knee osteoarthritis. The primary outcomes include parameters from the WOMAC scale.

However, from the trials that I gathered, some use Likert scale 0-4 for each question, some used visual analog scale (VAS).

How do I transform it to the same format/presentation so that meta analysis is possible?

Is there any formula?

Please help me.

Clinically it has been observed that some patients present with severe knee pain on one side and mild or no pain in other knee, on xrays Grade IV is not that painful as Grade III. So what are the possible reasons?

I am designing a knee simulation focusing on the meniscus. I want to add different material layers to the meniscus. I have tried to add composite layup to the menisci in a uniform way but the shape is complex and I don't know how to do this.

Knee osteoarthritis need good handling of pain complian as a disability and limiting activity we suppose that those patient need a rehabiltation plane especially before knee replacement or arthroplasty

Primary osteoarthritis - is

degenerative joint disease without any apparent underlying cause then what are the reasons of asymmetrical bilateral Knee OA?

All knee replacements, partial or total, will have parts made of a few different materials (likely metals and plastic). In most cases, each component is built from titanium, cobalt-chromium alloys, or a titanium and cobalt mixed metal.

I have used Vicon Nexus 2 for a walking trials with the lower body plug in gait model. However, the ASCII data exported has a column title Rknee angles and contains angles in X Y Z columns. Is there a way to directly output flexion/adduction/rotation angles instead ? Or am i missing something in the understanding of these XYZ outputs ?

Hello all, I am working on Gait related data which has sequences of joint trajectories in x, y, z axis. I want to know how to calculate joint angle lets say Knee Angle if I have 3 coordinates of hip, knee and ankle?

I've been trying to isolate total RNA from guinea pig's knee cartilage. I've tried Qiagen RNeasy kit, miRNeasy kit, trizol method with lots of modifications and have also used the RNaqueous total RNA isolation kit from Thermo Scientific but I've not been able to achieve RNA ratio of more than 1.4 for cartilage and 1.6 for synovium. In addition to the integrity the RNA conc. is also very low because the amount of cartilage available from the knee of guinea pig is very less (<15mg).

I homogenise the samples using Bead beater (bead mill).

If an MRI knee scan identifies a meniscal tear; what factors are taken into consideration to send for arthroscopy? If the scan has been generated from a GP referral: is there vetting to decide urgent or routine orthopaedic appointment from the results and onward freferral? Does it matter what type of tear? Do certain tears warrant more immediate intervention? If the scan also shows OA / degeneration, how much does that affect the decision to go ahead with a scope?

Hello,

I would like to calculate knee moments (for drop jump and one-leg jump for distance) using Vicon. How should I build the Dynamic Plug in Gait Pipeline? Force Plate Data are availabe + 15 markers.

Thank you in advance.

would like to know about treatment protocols related to knee OA.

I am starting to work on knee joint pain and see articles using paw withdrawal test to evaluate hyperalgesia occuring in the knee? Just curious why stimulating the hind paws instead of the knee to assess pain sensitivity. Much appreciate your inputs. Thank you very much.

I’m implementing a relatively highly cited academic research paper: “Interobserver

Reproducibility of Quantitative Cartilage Measurements: Comparison of B-Spline

Snakes and Manual Segmentation”. In short, the paper outlines how you can get a

B-spline to outline knee cartilage in a 2D slice of an MRI. I am stuck at minimizing the

cost function using gradient descent. I do not know how to gracefully apply a partial derivative to a line integral where the line is a B-spline contour in a 2D image. A full explanation of the problem and my current solution is attached, however I make a poor assumption to get to that solution. If anyone could double check my math or has any ideas I would greatly appreciate it.

question is more related to asking for collaborators to join me in this project. I experienced terrible knee pain due to emotional stress of losing a parent. Once I handled my emotional pain , the knee pain disappeared too. Am sure there are many out there with similar experiences, lets get together and work on it.

How did a health crisis translate to an economic crisis? Why did the spread of the coronavirus bring the global economy to its knees?

I'm working on a project which should identify problems in the human gait.

After a research I've made I decided to use an IMU sensor comprises from an accelerometer and gyroscope. I've attached it to my foot and to my knee and I'm getting x,y,z values of the accelerometer & gyro.

My question is - what next?

I red in some articles that I should combine the x,y,z of the 2 sensors or use Kalman filter, but actually I need some guidance about how to proceed from here.

my hardware is - Arduino Nano 33 IOT (with built in IMU)

I have to write a systematic review and I need maximum studies regarding knee osteoarthritis patients please suggest me all relevant databases.

Hi all,

I have been collecting cross-sections of a mouse knee joint, and I keep seeing some differently coloured, yellowish tissue on the anterior side of the joint, but I'm not too sure what this is?

Please refer to the attached optical scan of one of my sections and let me know if you have any insight.

Thanks in advance,

Jordan

is there literature about power lifting and weight lifting and the hamstring curl or knee flexor capabilities?

Most they do squat, deadlift, goodmorning, straight leg deadlift, but it seems the leg curl of knee flexors are less trained. For instance biceps femoris has an aponeurosis and the knee flexor could be underdeveloped.

In practice I see people squating 100+ but leg curl with very low KG.

For intra-articular injection of MIA, I have seen most people to inject 25 or 50 ul. Wondering for drug injection into the knee/synovial space, can I use a greater volume like a 100 ul? Or will it just cause leakage?

Hey, all there,

I have to write a systematic review and I need maximum studies regarding knee osteoarthritis patients please suggest me all relevant databases

Thanks

I am studying force transmission through the synovial layer of the knee and would like to dissolve the fat pad so that I can see the fibrous array. Does anyone know of a solution that allows one to do this?

Hello, everyone!!! I hope you all are doing well. I have a research project in which I have to evaluate certain variables among Knee Osteoarthritis patients. I am facing some limitations at my study location(Physiotherapy Clinic) as some of the patients (who have been diagnosed with knee OA) referred by a physician or orthopedic consultant come without any radiographic investigation. Due to the lack of patients, I have to allocate such patients in my study as well. Please suggest to me how I categorize such patients as with mild, moderate or severe OA conditions based on their symptoms and physical examination.

Physiotherapy and exercise show short-term improvements in physical function. I would like to know particularly cycling exercise for treatment.

What are the causes of knee pain; what are some remedies?

Context: I recently visited Pakistan and met many of my relatives in their 50s from a certain industrial region who had knee problems. My guess is that an underlying cause is bad water quality from chemical seepage into the drinking water. What are your thoughts?

We have been culturing MSCs from knee bone chips in which the MSCs migrate out into the culture flask. These have been taken from someone else in our group and resurrected from frozen (P3-4). However, when we have cultured these cells from frozen we seem to be getting a cellular contamination that is rapidly proliferating (can generate 12 million cells in 5 days, T175) that takes over the flask that wasn't seen in culture with the other group. Can anyone help with identification of what these cells might be and suggest any flow markers that could show up?

Note: magnification on image is x20 and cells have been seeded at very low confluency to show morphology.

Thanks for your help.

I want an initial direction, like how can I use IMU sensors on knees (e.g upper leg and lower leg ) to estimate body state e.g running, walking, climbing, etc. The basic idea I have is to use 2 IMU sensors on knee position (upper and lower leg) , and to get data or make a data set of it. Then process it using deep learning e.g CNN or ANN etc. But point is..are there data sets available on which I can test CNN etc to see either it works or not. Need guidance about data sets, from where could I get IMU knee based data sets, so that I can focus on my algorithm only.

I am trying to stain bone tissues from human knees however I am having a hard time with antigen retrieval. I use citrate buffer and a water bath set at 85 ° for 20 minutes and I leave the tissue in the solution until it reaches room temperature. I still have some tissue left but they become so fragile that they come off after a few washes during blocking step.

I do use positive charged slides too.

Can anyone suggest a good method for unmasking antigens when using bone and/or cartilage?

Hello,

I am looking for a kinematic gait data set with knee osteoarthritis subjects. I'm having a tough time finding anything other than normal subject data.

I would specifically need a kinematic data set with minimally knee ad/abduction, flexion and extension.

Do you know of any possible sources?

Thank you.

Hi all, thanks for your help in advance.

I have several health measures relating to pain that are included in a study I am working on. In case it's important, they are the following:

· Numerical rating scale for back pain

· Inflammatory back pain questionnaire

· Oswestry Disability Index

· Non arthritic hip score (NAHS)

· Knee osteoarthritis outcome score (KOOS)

· Disability arm shoulder hand (DASH) questionnaire

As you can see, they mostly refer to pain that resides in specific areas of the body. I am only interested in if they experience pain in any of these areas, so would like to merge them all into a 'pain' variable, likely binary (0=no pain 1=pain).

Are there are recommendations or procedures for doing this? The process could range from the very simple (1=report of moderate pain in any questionnaire) to the more complex (a confirmatory factor analysis of all the questions in each of these questionnaires using a 2 (no pain or pain)/3 (no pain, some pain, extreme pain) model framework).

This will end up in a structural equation model exploring how variable1 affects variable 2. Pain is associated with both variable 1 and 2. There will be a large sample size (>1000) but also potentially a lot of variables, hence the attempt to reduce these pain questionaires down into a single variable.

Posterolateral knee pain can be associated with the presence of a fabella and this incidence may be referred to as a fabella syndrome. The fabella syndrome is a rare cause of posterolateral knee pain and usually not diagnosed.

I have followed the advice on this site, Penn State research papers and numerous www.ncbi.nim.nih.gov articles. A man was diagnosed with osteoarthritis of the knee due to a severe motocross accident. I've attached his x-rays from before and after the plates were finally removed from his leg which was one year after his crash. I need advice. Does the second set of x-rays reveal a total healing, or are we just seeing the effects of numerous chondroprotective supplements which were given to him in the hopes of opening the space in his knee? I ask because it seems to soon to experience this level of healing. I've also attached the patient's supplement list with dosages and dates. Please understand that the supplement list was created for my benefit and not necessarily to be read by others. By this, I mean I was only attempting to keep my research straight.

I'm working with my senior design group to create a customizable brace for PCL injuries. We are able to find general specs for fitting. We are looking for screw hole sizes to give us a starting point to help us join the pieces together.

We know that tibial components are the most vulnerable to loosening. We know that infection always needs to be excluded. We know that the problem is multifactorial and involves surgical, implant and patient factors. However, what should we do to minimise the risk of aseptic, tibial component loosening ?

We use the ConceptBase system for analysing larger networks, e.g. enterprise models. Many queries rely on the transitive closure of some relations. If the graph has many loops (i.e. bi.directional transitive relations), then the DATALOG engine of ConceptBase gets to its knees.

Are there algorithms or heuristics known that deal specifically with this case? The DATALOG engine of ConceptBase does use tabling, i.e. it computes one fact only once. Still, graphs with many links pose a challenge.

Any hint is welcome!

Manfred

In TKR, a large amount of research focusses on improving the long term survivability of the prosthesis, which largely depends on component placement.

The rotation of the femoral and tibial component , amongst other aspects, can be variably decided amongst different surgeons depending upon the surgical/ anatomical landmarks chosen or the soft tissue tension/balancing.

I would like to know the preferred method followed by different surgeons and discuss the merits/ demerits of each.

Septic knee is usually drained via lateral approach and lateral retinacular fibres are not repaired following the procedure. Will it be a concern when planning for medial parapetellr approach on the same knee for any procedures later?

I would like to assess the pressure pain threshold in hip osteoarthritis and i cannot find reported sites of measurement as in knee osteoarthritis.

Looking for any papers that look at the use of ellipticals and knee stresses/kinetics alone and/or relative to walking/jogging.

Osteoarthritis is the second most common rheumatologic problem and it is the most frequent joint disease with a prevalence of 22% to 39% in India. OA is more common in women than men, but the prevalence increases dramatically with age.

As we all Know that Medicine get better, Technology get better, Diagnosis tool get better, Physiotherapy Prevention and management get better still the prevalence increases year by year..........

Thats mean all this get fail for reducing the prevalence of Knee OA among world.

What are the reasons for this?

With dynamometer tests, we get torque values. However torque = distance x force. Since the biodex (or the labchart if you're reading the data from the data from the computer) does not ask for the lever length (e.g. for knee extensions, we have to adjust the attachment length accordingly to the participant's shin length), and since the motor of the dynamometer measures the force in the point of rotation, how can it calculate the torque without knowing the distance?

We observed lower-limbphagia from phalanx to knee in transection models of spinal cord injured rats. How can we manage and prevent it ?

Dear Friend,

I am wondering what is the new types of implant?

Thanks

I am doing a cross-sectional study, I want to find the sample size. the study is on the prevalence of neuropathic pain in knee osteoarthritis. I will use raosoft.com margin of error 5% and CI 95%

I have 3 objectives in ILP model.The first has to be maximized and the second, and the third should be minimized.

I would like to compute the knee point of the generated Pareto front.

Didi you have an idea about the formula ?

thanks

I wanna investigate wear resistance of a part of some implant that need high wear resistance, but I don't khow which part has more need..

IKDC purpose is to detect improvement or deterioration in symptoms, function, and sports activities due to knee impairment. and KOS (ADL) purpose is to determine symptoms and functional limitation in usual daily activities caused by various knee pathologies.

we face many patients, females, young and complaining from cartilage softening and only known while doing knee arthroscopy .

the alignment angles was within accepted range.

what to do to eradicate this lesions

I'm looking for a joint ultrasound dataset, it can be knees, shoulders, feet, any kind of joint is ok. I have seen different musculoskeletal ultrasound images; however, nothing more than a few images.

Thanks.