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My study setting has 30 villages
First step: I included all the 30 villages in my survey
Second step: in each village 10 households with infants 12-23 months were randomly recruited using a random walk method
Question1: If I include all the 30 villages, is it still a two-stage cluster sampling method?
Question 2: To what extent does including the same number of participants from each village affect the representativeness of my sample?
Thanks
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I like modeling, when you have good predictor data for the model(s). But you have to have those predictor data.
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Hi team,
Appreciate someone’s insight on my query. I am extracting vitamin B2 (riboflavin) and FMN analytes from infant milk formula and identifying/analyzing it in reverse phase liquid chromatography using linear regression. We run multiple injections of pure working standards (WS’s) before samples and quality controls (QCs) in between samples of riboflavin and FMN to check if the conditions are same and consistent throughout the run and whatever results we get are true results. I am facing a problem in which QC’s of FMN analyte peak area start getting increase as the injections reach to the end of the sequence. It is the same vial, same position in the autosampler but peak area gets increased. Does anyone faced the same type of issue?
Thanks
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yes bubbles can affect the reproducibility of the peak because when there are bubbles in the syringe, the volume of mobile phase that is aspirated from the syringe (which is used to inject and aspirate the sample) is not correct due to the bubbles of air so the volume of the sample is corrupted.
To monitor the carry over try to run a sample and then do another one by injecting only the mobile phase: you should not see peak or see a very small one
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New infant acquired methemoglobinemia case data, found for an upcoming book, show infant morbidity and mortality down to about 1 ppm nitrate-N. USEPA missed these data sets when they calculated or multiply reaffirmed the basis for the existing 10 ppm nitrate-N drinking water standard.
Based on this finding and others you might have, what should revised standard concentrations for nitrate-N and derived nitrite-N be and how would you perform the calculation?
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Sources of data
1. Kenny, J.F., Barber, N.L., Hutson, S.S., Linsey, K.S., Lovelace, J.K., and Maupin, M.A. 2009. Estimated use of water in the United States in 2005: U.S. Geological Survey Circular 1344Exit Exit EPA website.
2. Nolan, B.T. and Hitt, K.J. 2006. Vulnerability of shallow groundwater and drinking-water wells to nitrate in the United StatesExit Exit EPA website. Environmental Science and Technology. Vol. 40, no. 24, pp. 7834-7840.
3. U.S. Geological Survey. GWAVA dataset for shallow groundwater and drinking water wells
References and links to other data sources
1. Dubrovsky, N.M., Burow, K.R., Clark, G.M., Gronberg, J.M., Hamilton P.A., Hitt, K.J., Mueller, D.K., Munn, M.D., Nolan, B.T. Puckett, L.J., Rupert, M.G., Short, T.M., Spahr, N.E., Sprague, L.A., and Wilber, W.G. 2010. The quality of our Nation’s waters—Nutrients in the Nation’s streams and groundwater, 1992–2004: U.S. Geological Survey Circular 1350Exit Exit EPA website.
2. DeSimone, L.A. 2009. Quality of water from domestic wells in principal aquifers of the United States, 1991–2004: U.S. Geological Survey Scientific Investigations Report 2008-5227Exit Exit EPA website.
3. Madison, R.J. and Brunett, J.O. 1985. Overview of the occurrence of nitrate in ground water of the United States, in National Water Summary 1984-Hydrologic Events, Selected Water-Quality Trends, and Ground-Water Resources: U.S. Geological Survey Water-Supply Paper 2275Exit Exit EPA website, pp. 93-105.
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Are there any studies or publications regarding the optimal duration of a nap, for infants to regain their best performance/homeostasis?
Thank you!
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Thank you!
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Dear All,
I hope my message finds you well.
I'm doing a diagnostic study to find out the most accurate method to diagnose fever in febrile infants. I'm using axillary temperature mesuramtent as an index test and rectal temperature as a reference test. The total population size is 201. The number of infants diagnosed using axillary method were 159, whereas rectal temperature was positive for every subject. The number of infants who had normal temperature using axillary method and had fever using rectal method were 36. How can I calculate the sensitivity and specificity? I find it confusion a bit because I don't seem to understand how to allocate the numbers in the cross-tab.
Thank you for your cooperation!
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Hello again Yazeed,
If you're only sampling cases for which the referent condition/method (here, rectal temperature) shows positive, you'll never be able to estimate specificity for the trial condition/method (here, axillary). The only way to estimate specificity is to amass a number of cases in which the referent condition shows negative results, and record the trial condition results for those cases.
Since all 201 of the cases were positive for the referent condition, then did you test only 159+36 = 195 of these cases using the axillary method? Was there some reason for not testing the other 6 cases (or were these records somehow unusable)?
Good luck with your work.
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Are there any references for Estimated Average Requirement (for minerals and vitamins) of infants less than 6 months?
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You can check this: https://www.nrv.gov.au/introduction for more information
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A 10 month premature baby is not able to eat on his own. It had a CDH surgery right after birth and a re-herniation at 6 months. The smallest amount of food causes choking and vomiting, visible trouble in swallowing (but only the food). The baby is fed through an NG-tube.
- acid reflux excluded
- vascular ring excluded (an esophageal stricture had been suspected)
- another re-herniation excluded
The baby is under a Speech and Language Therapist care. Gastrologists can't find the cause. What are the most common diagnosed problems of CDH babies responsible for feeding difficulties? How to treat them? What should be checked?
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Can you elaborate more regarding inability to eat ; is he can not suck , in coordination sucking -swallowing or anorexia , what about his Hb
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I need a set of images of emotional faces (angry or sad; neutral; happy) of infants. I would like to frontally present these faces on a screen in a computer experiment. If infant images were matched in size, luminance, position, etc, with other images of adults, it would be great! Yhank you
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Immature green pods of faba bean should be avoided in diet system, particularly by kids 
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Dear friends l am really happy to receive your answer, however, there is some other toxic material synthesized during pod development of fababeans, cyinoalinine, which digested to reliase cyanide a toxic to consumer ..... in developed pod this above mentioned compound will detoxified into as I recall to serine....
Please keep in contact if you do not mind
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I have analysed infant milk powder with Raman microscopy. However, the Raman shift (cm-1) is very high and it's not what I was looking for. Usually the Raman shifts of milk powder is between 400 cm-1 and 4000 cm-1 and this is beyond those number. What went wrong? I am also sure that the unit is cm-1 and not something else.
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I am trying to measure the bilirubin concentration in the infant rats’ tissue brain. However, I am unsure whether I can use Bil - Hall’s bilirubin staining method as most previous studies have been done on the liver and kidney tissues.
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The protocol you sent is merely used for measuring total bilirubin. At the moment, I am interested in assessing direct bilirubin. Could you possibly tell me how I can estimate that one if you know?
Thank you.
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I am working on human health risk assessment from exposure to heavy metals in ground water through ingestion and dermal route. I am calculating separately for adults, children and infants because of the different ingestion rate.
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Very good initiative. My best wishes!
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What will be the prognosis of tuberous sclerosis in an infant who got diagnosis of tuberous sclerosis just at the age of 2-3 months through scan.
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Hi,
Here are few references which could be helpful for you:
Randle SC. Tuberous Sclerosis Complex: A Review. Pediatr Ann. 2017 Apr 1;46(4):e166-e171. doi: 10.3928/19382359-20170320-01
MacKeigan JP, Krueger DA. Differentiating the mTOR inhibitors everolimus and sirolimus in the treatment of tuberous sclerosis complex. Neuro Oncol. 2015 Dec;17(12):1550-9. doi: 10.1093/neuonc/nov152. Epub 2015 Aug 19. PMID: 26289591
Wang S, Liu Y, Wei J, Zhang J, Wang Z, Xu Z. Tuberous Sclerosis Complex in 29 Children: Clinical and Genetic Analysis and Facial Angiofibroma Responses to Topical Sirolimus. Pediatr Dermatol. 2017 Sep;34(5):572-577. doi: 10.1111/pde.13204
Kadish NE, Riedel C, Stephani U, Wiegand G. Developmental outcomes in children/adolescents and one adult with tuberous sclerosis complex (TSC) and refractory epilepsy treated with everolimus. Epilepsy Behav. 2020 Oct;111:107182. doi: 10.1016/j.yebeh.2020.107182
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In our recent study comparing the developmental status among premature babies versus term babies, we end up with this conclusion " Half of the children had developmental delay in our sample from rural Rwanda. Preterm and/or LBW infants were more likely to have developmental delay, and the main predictor of developmental delay was stunting, with high rates of stunting observed also in term/NBW infants. Interventions to reduce undernutrition and prevent prematurity and LBW, alongside investments to promote early stimulation for optimal development, are needed if gains in addressing developmental delay are to be made."
So in the order to help our study to have an impact on the field I would like to know which early child stimulations methods to be use successfully in middle in come countries especially in Rwanda.
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Having worked with families of children from low socioeconomic backgrounds, Educating families about individual temperament and cues which signal "ready to learn" and an interest in the exercise come before stimulation. Nutrition of course is key.
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which one is the updated and validated questionnaire for measuring infant and young child (6-24month) feeding practice without taking interview? is there any that measured in likert scale or other rating scale?
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I am trying to analyze some questions for infants. I want to find some questionnairs used by birth cohort study or some commonly uesd questionnaires of infants.
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Hi,
Bayley Scales of Infant and Toddler Development, however, requires country-specific standardization.
Probably you can look at the cross-references from the references given below
Wu W, Qu G, Wang L, Tang X, Sun YH. Meta-analysis of the mental health status of left-behind children in China. J Paediatr Child Health. 2019 Mar;55(3):260-270. doi: 10.1111/jpc.14349
Cook F, Conway LJ, Giallo R, Gartland D, Sciberras E, Brown S. Infant sleep and child mental health: a longitudinal investigation. Arch Dis Child. 2020 Jul;105(7):655-660. doi: 10.1136/archdischild-2019-318014
Wozney L, Radomski AD, Newton AS. The Gobbledygook in Online Parent-Focused Information about Child and Adolescent Mental Health. Health Commun. 2018 Jun;33(6):710-715. doi: 10.1080/10410236.2017.1306475.
Stewart SL, Hamza CA. The Child and Youth Mental Health Assessment (ChYMH): An examination of the psychometric properties of an integrated assessment developed for clinically referred children and youth. BMC Health Serv Res. 2017 Jan 26;17(1):82. doi: 10.1186/s12913-016
:
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I am curious about the use of art therapy to encourage mirroring and bonding with mother and infants dyads. I can think of prompts for the mother that are easier done without an infant but nothing she could do safely with her baby. Any suggestions?
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Finger paint or hand printing.
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Hi everyone, I came across something strange in HPV PCR of an infant. The specimen was CSF and the positive and negative control didn't have any problem but I'm not sure about the positive band which have been detected on agarose gel.
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NO as i know it is diagnosed by smear
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Hi,
I am processing infant kinetic data. However, the kinetic graphs I obtain seem a bit noisy. I wonder which filter are recommended to use in Vicon Nexus for the infant kinetic data (.MOT file)?
1. Which frequency should I use (0.01, 10, 50, 100, 200 or 300 Hz)?
2. Is it 2nd order (with lag) or 4th order (zero lag)?
Thank you.
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Ever since Groningen Protocol was regulated in 2004 and proposed as a medical protocol by Dr. Eduard Verhagen- professor of pediatrics and medical director of University of Medical Center Groningen- as a purpose to extend the existing legality of euthanasia to newborns (and late-term pregnancies), Verhagen addresses in Pediatricians call for a nationwide protocol for the ending of life of unbearably and incurably suffering newborns. “ This is a subject that nobody likes to acknowledge, let alone discuss. But, it is in the interest of newborns who have to endure unbearable suffering that we draw up a nationwide protocol that allows each pediatrician to treat this delicate question with due care, knowing that they followed the criteria.” (The University Medical Center, 2004). The most important condition is euthanasia is only to be used if the baby is experiencing extreme suffering (pain) that no treatment can alleviate, in which the protocol is invoked purely as a final act of mercy. This means that ethical issues of euthanizing severely disabled infants have been put in the debate in regards to the morality of euthanasia if it’s performed on fragile subject such as infants. This has raised many to question of to what extent should euthanasia be performed on infants and newborns with severe conditions such as spina bifida or is it “too damaged’’ and “ immoral’’ for society to advocate this practice that originated from Northwestern Europe. The topic has induced many debates and questions that revolve around euthanasia as a medical option to help relieve pain for infants and newborns
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This Groningen Protocol is about active euthanasia in newborns and active euthanasia is still not allowed in many countries, including ours. But, passive euthanasia is legalized and can be utilized in newborns also, if used properly.
The prospect of euthanasia in my opinion is bright in days to come, because there are multiple neonatal conditions where the future prognosis is too grim, both for the child and their caregivers. Many a times, these children become the victim of neglect, as the parents or caregivers are drained out both emotionally and financially. Otherwise, parents just waste away their lives bonding too much with their debilitated offspring. Either way, the society is at a loss.
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Can separating an infant from its bio mother within the first few months of it being born cause PTSD? I heard the theory the other day and am curious if there's been scientific study specific to this phenomena.
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Infant adoption: Psychosocial outcomes in adulthood
S Collishaw, B Maughan, A Pickles - Social psychiatry and psychiatric epidemiology, 1998 -
Adoption studies are able to provide important insights into the impact of changed rearing environments for children's development. A number of studies reporting on the childhood adjustment of adoptees have found an increased risk for disruptive behaviour problems when compared with children brought up in intact families. The long-term implications of adoption for psychosocial adjustment in adult life are less clear. We have used data from the National Child Development Study (NCDS) to examine the psychosocial functioning over a number of life-domains of an unselected sample of adoptees, non-adopted children from similar birth circumstances, and other members of the cohort. Adopted women showed very positive adult adjustment across all the domains examined in this study, whilst our findings suggest some difficulty in two specific domains (employment and social support) for adopted men. Implications of the fndings are discussed.
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I want to find out respiration rate for the infants and adults. The range for rate is 0 to 60.
I have written algo but that is working on slow rate only. For High rate, I am getting slow output only. Please suggest me any method to findout output for the whole range.
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Please refer to the following article for this:
MATLAB code provided in MathWorks File Exchange:
Respiratory rate estimation from ECG and/or PPG:
Follow a series of publications on the estimation of respiratory rate from ECG/PPG:
Hope this will help to implement your idea.
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Hello all,
I’m really a novice in the field and just started to learn to use the EEGlab. I’m writing because I’d like to run a power/frequency analysis on the data I have – and I’ve got a question.
The data was collected from 9-month-old infants using the EGI system, HydroCel Geodesic Sensor Net with 128 channels. We’re interested in brain activities occurring during a 5-sec long interval. Each infant did 7 to 9 trials (i.e. each infant gave us 7-9 intervals to analyse), which seems very small as a number of trials but it’s not very unusual for infant EEG studies + the study is a pilot.
I’ve been using a NetStation to pre-process EEG so I thought it’d be easier to segment the data, do the artefact detection and replace bad channels identified, and then import these epoched data into the EEG lab to do the FFT (or other transformation methods for the power analysis). But I was advised a few times to use the EEG lab from the beginning of the preprocessing (i.e. epoching, artefact detection and interpolation). Is there any difference between these two? If so, what is the difference and what may be the pros and cons of each method?
I hope this makes sense – but please get in touch if you can help me with this and/or need more information.
Thank you very much in advance, and I hope you have a lovely day.
Kind regards,
Saya
*********
Sayaka Fujita
Marie Skłodowska-Curie Early Career Researcher (MOTION)
Department of Psychology
Lancaster University
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Ritika Jain Thank you so much for your answer!
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My specific interest is prenatal-onset group B strep disease.
​1) Estimates of the Burden of Group B Streptococcal Disease Worldwide for Pregnant Women, Stillbirths, and Children. Anna C. Seale et al. Clinical Infectious Diseases, Volume 65, Issue suppl_2, 6 November 2017, Pages S200–S219. 2) Maternal group B Streptococcus-related stillbirth: a systematic review.  C Nan et al.  BJOG. 2015 Oct;122(11):1437-45. ​ 3) www.who.int/reproductivehealth/topics/maternal_perinatal/stillbirth/en/ "An estimated 2.6 million stillbirths occur annually."
4) https://www.who.int/immunization/newsroom/press/news_group_b_strep_stillbirths_infant_deaths_2017/en/
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Dear Marti, this is something we shall be doing too. However, we welcome your precious ideas too on this...
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Dear all
I'm working with infants and want to track their lip movements. My concern is that they won't accept any marker on their lips. I^ve never used any motion capture system but plan purchasing one in the context of my research. Any suggesting is very welcome.
Thanks for your assistance...
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Dear Dr Havy,
What level of accuracy are you looking for?
Wouldn't two cameras (sagittal / frontal) be enough?
With real motion capture system, Vicon Cara could certainly help you.
Best regards,
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I would like to take training in your project even if our country of Ethiopia Aquaculture is infant ,there is a student that take this department.So I am voulenter to participate on your project.
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In India Some Government Institutes and , in Andhra Pradesh, in SIFT, kakinada, both long term and short term training are available
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Please mention only recent evidences supporting your view and what is today the best practice we can implement to these children...please do not mention all aspects...take position...
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when you say 'infants' , whats the age group you are referring to?
for most of us, audiologists and SLPs the typical age group is 1.5 yrs and above,
And there is no debate there... auditory verbal therapy is a valid option there...
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WHO RECOMMENDATION IS as :
"" The Committee recognizes the difficulty in identifying infants infected with HIV at birth in settings where diagnostic and treatment services for mothers and infants are limited. In such situations, BCG vaccination should continue to be given at birth to all infants regardless of HIV exposure, especially considering the high endemicity of tuberculosis in populations with high HIV prevalence. Close follow up of infants known to be born to HIV-infected mothers and who received BCG at birth is recommended in order to provide early identification and treatment of any BCG-related complication. In settings with adequate HIV services that could allow for early identification and administration of antiretroviral therapy to HIV-infected children, consideration should be given to delaying BCG vaccination in infants born to mothers known to be infected with HIV until these infants are confirmed to be HIV negative.""
what is a practical clinical approach in such cases?? advice to mothers....
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In South Africa we follow the above. All babies receive BCG at birth as per national immunization schedule unless they are born premature or ill when it is given before discharge from hospital. All mothers are screened routinely for HIV (2x during pregnancy and at birth if not tested before). If the mom is found to be positive - PMTCT is started for mom and baby once born and is very effective in preventing infection. If any direct contact with TB patients in the home the baby is started on INH prophylaxis. This may differ in areas of the world with low HIV/TB incidence and the BCG can then be safely delayed.
ELISA can be false positive in babies up to 18months due to mom's IgG crossing the placenta. If the mom is HIV + we do a PCR at birth and again at six weeks to confirm HIV status. Another final test is done six weeks after stopping breast feeding. The PCR will probably be replaced by P24 antigen or a another test with shorter window period in the near future. In low income settings exclusive breast feeding is advised for 6 months and then completely stopped as long as mom is on ARV, as the risk of malnutrition is weighed against the risk of HIV infection with an undetectable viral load. Mixed feeding is discouraged due to higher risk of HIV transmission through the gut.
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I heard from many people when an individual becomes old aged s(he) is treated as a child. is it right? If yes, Why?
Thanks.
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Some cultures value age very highly because it is associated with "wisdom", some cultures value childhood very highly because children can encourage in their spontaneity, creativity and zest for life.
The comparison between old age and childhood is poetic and does not have to be humiliating. Here, for example, the "memory of childhood" can evoke very valuable thoughts; the need for care also has early childhood and old age in common. This does not have to be evaluated negatively in any way. There are - unfortunately - also derogatory judgements in a society, for both childhood and old age.
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Are there any public MRI datasets for infants.
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Hi,
I think that the address for this data set is:
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According to the new ERC 2015 Guidelines on Resuscitation
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Sure? For lay-people...?
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i want a book or any file that talks about neonate or pediatric ventilation
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Some times we want to conduct a reliability study on some diagnostic modality for a specific disease but the gold standard for the diagnosis of that disease is either invasive procedure or surgery. which is not justified to be performed on normal individuals (control group). In such a case is it justified to take control group as negative of the gold standard?
For example:
We want to diagnose Infantile Hypertrophoid pyloric stenosis (IHPS) with the help of ultrasound but the gold standard for its diagnosis is surgery. If we perform Ultrasound of 50-infants with projectile vomiting and the sonographic findings of 40 of them are likely for IHPS and 10 for normal. But after surgery (Gold-Standard) 38- were confirmed as IHPS but 2 were false positive. Now we want to perform ultrasound of 50-normal (control). Is it justified to put all the 50 normal infant as True negative and false positive as 0 of the gold Standard, To perform chi-Square statistics?
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Hello,
If I well undertood your question, I think here you can use the Bayes Theorme, based on clinic litterature if you have about this specific test. we can consider the ultrasound results as a priori information about the clinic test, and the Gold-standard one as the real data (x).
I can reformulate your problem as :
If your test results come back positive when using ultrasound method, what are your chances that children actually have the disease (with G-S method) ?
CHELLAI. F
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I am hoping to analyze HR collected and was looking for advice on methods for analyzing HR and linking it to specific tasks and/or overt behaviours
thanks!
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Hi dear Lori
I did not research on this topic but I searched for your question and I can introduce this article to you:
I hope you find it helpful
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I am working with groups who do not have a written language and need some research / project info on training people in this community to be supporters of other women in their community on topics related to infant and young child feeding.
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Thank you for suggesting these resources. I am using the UNICEF IYCF images though we were receiving some feedback that the foods didn't look enough like local culture in the country we are using them in thus I was looking for more images.
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The change in the composition of gut microbiota in early infancy has been reported to correlate with the future development of many kinds of diseases such as allergy, inflammatory bowel diseases, or obesity. However, there seem to be few studies on the impact of the change in oral microbiota in early infancy on their health in later life. In adulthood, changes in the oral environment are thought to be linked to diseases like metabolic diseases or vascular diseases. Do you think changes in oral microbiota in infancy can also have a substantial impact on future health similarly to gut microbiota?
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Dear Dr. Jenmalm
Interesting articles!
Thank you so much for providing those useful informations.
Best regards,
Naruaki Imoto
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What are the pregnancy, obstetric and infant complications of Hepatitis C infection with and without HCV viremia?
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HCV infection in pregnancy has many aspects both for mother and child. Regarding effect on each other, neither alters the course of the other in general [except if the HCV related liver disease is end stage when effect on mother and fetus are due to the decompensated liver rather than HCV per se]. Mothers having high HCV RNA and concurrent HIV infection are more likely to pass HCV to fetus [3-5%]. Since no vaccination is available against hepatitis C it is always advisable to screen pregnant women for Anti HCV. If RNA is present treatment with DAAs can be instituted in early phase of pregnancy to prevent transmission to offspring. It is best to avoid surgical interventions for delivery [like ARM, CS] Breastfeeding is not contraindicated in HCV positive mothers. Acute HCV infections if detected during infancy [rare occurence] should be treated.
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I am particularly interested in the model you have created of the infant skeleton, the lower limb region. I am working on a skeletal/biomechanical model of congenital talipes equinovarus (clubfoot deformity) and am investigating what has been done in creating skeletal infant lower limb models. Thank you for your time, I look forward to your response.
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Dear Emily,
Thanks for your question.
On tose papers I used non-anthropomorphic models, but you may contact Richard Kramer from Federal University of Pernambuco ( ). I use to use his anthropomorphic models. His working team created a family of phantoms. You may use CT images to create your phantom too (even personalized ones). If you are interested to create your phantoms you may contact me by close message.
Hope it may be useful,
Gabriela
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Can you recommend me a laboratory to assess cortisol and alfa-amilase in saliva? I am from Chile and I need to determine both biomarkers in infant's saliva. Any information or your experience in this research field can help me to develop my study. Thank you in advance.
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@Cara Skon Hegg - awesome, thank you. I will write you an email. Thanks :-) Teresa
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The ICRP Publication 101 "Assessing Dose of the Representative Person for the Purpose of Radiation Protection of the Public" defines the deterministic and probabilistic approaches to find the dose of the Representative Person from doses incurred by population members. Are results for members of the group of different ages included in forming the average or the 95th percentile of the dose distribution, or shall they be treated separately? I am not sure, although the example for the probabilistic approach in B.7.2 of ICRP 101 would suggest the first case. Simply put, at the end of the analysis, is there only one Representative Person with one Dose to the Representative Person, or are there Representative Persons for each age group, e.g. Representative Infant (1 y), Representative Child (10 y), Representative Adults (adult).
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You are on the right track but you need to understand the logic of the situation.
The need to involve various groups depends on the expected exposure situation. If you e.g. are dealing with staff > 20 years from a minor local onsite release, you limit your group accordingly. Observe that if you are concerned with releases to the general public you might still be OK with the average groups.
You can check it yourself by making your own parallel calculations. You might find that one infant + one adult etc. for all the groups, exposed at one situation may give you the same detriment/person as one individual receiving the same dose distributed over a lifetime.
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Dear community
I would like to ask if you are aware of any tool (Matlab/toolbox, etc.) that calculates the "lag between BOLD time series", as described in the following publications:
Thank you very much.
Best regards
Andras Jakab
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Dear András Jakab , please take a look at https://la.mathworks.com/help/signal/ref/xcov.html, which computes the lagged cross-covariance function. You just have to apply xcov to multiple ROI timecourses and store the results in the anti-symmetric matrix T.
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I stumbled upon a research idea that seems significant and might reduce Shaken Baby incidences. Currently I am not affiliated with a hospital or university to use their IRB for review.
I'm not sure I need an IRB because I'm comparing the outcome of two activities mothers engage in normally with infants.
What are you thoughts?
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I would call the chief IRB authority in France for their direction. For further discussion, you may want to contact a university-related IRB in France near you and ask for their help and advice.
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Do you think acute diarrhea in infants
Affect the development situation
For physical equipment in infected infants?
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https://www.researchgate.net/profile/Fekri_Dureabشكرا على المشاركة د. فكري دريب
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Usually KD is recom as one of the last option in a child with drug resistent epilepsy (DRE): A new therapeutical point of view should be a new option in a infant?
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Is it possible to start KD as first option in GLUT1 syndrome?
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Some previous studies reported geographical variation in the composition of the gut microbiota in early infancy before weaning. In particular, infants in Scandinavian countries had gut microbiota dominated by bifidobacteria in early infancy, while those in southern European countries didn't.(Nat Rev Gastroenterol Hepatol 2012: 9: 577–89.doi:10.1038/nrgastro.2012.156) Recently we confirmed that Japanese infants also have bifidobacteria dominating microbiota in their guts. 
 Which factors do you think can be attributed to this similarity in the composition of the gut microbiota between geographically, ethnically, and culturally distant regions?
 I have come up with several factors such as nutrition (breast, mixed, or exclusive milk feeding), genetic backgrounds, the gut microbiota of their family members, but none of them seems to answer the question.
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Dear Dr. Gänzle
Thank you very much for your reply.
 As you mentioned, the mode of delivery and feeding methods seem to be important for the bacterail colonization to infants' guts. We confirmed  in the previous study (https://rdcu.be/3q6M DOI:10.1038/s41372-018-0172-1) that mode of delivery had a substantial impact, however, there were no differences in the composition of gut microbiota between breast-fed infants and mixed or exclusively milk-fed infants. 
 Regarding the impact of feeding methods, you mentioned that the human oligosaccharides are the same in Japanese and Scandinavian mothers. Has this been established?
 I still wonder whether this similarity in human milk between the two distant regions also applies to other ethnic backgrounds, because even among European countries, the composition of the gut microbiota varies even after weaning period (Microbiology (2011), 157, 1385–1392, Journal of pediatric gastroenterology and nutrition 51(1):77-84). 
Does the similarity come from just the way the mothers give milk, from the genetic factor, or some common lifestyle or culture (for example, fish based diet) between the two?  
It would be grateful if you could advise me on this topic again.
Sincerely
Naruaki Imoto
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Has anyone had success with seeing premature infants be able to breast feed prior to being able to bottle feed at approximately 34 weeks of gestational age?
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I agree with Melissa. In our experience, early skin to skin has allowed infants to recognize the breast faster by 32-34 weeks, to promote brief but early latches, and then progress to more successful breastfeeding as their clinical status improves. We use fortified supplementation to support growth that continues, in many cases, for a short period after discharge.
Mothers also show greater skill and confidence prior to discharge.
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I am interested in both observational and self report measures.
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There's also this, but it has not been used for infants less than 9 months old. You need a time stamp on the recording, and behaviours are coded for 30 consecutive 10-second blocks.
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i want to work on a child of 3-6 month or above. my main focus is to study speech production of children depending on how fast they assimilate or pick. And the other topic is to make a comparative study of speech production and understanding capacity of children language between 3-9 month. furthermore i intend to see a critical examination of infants assimilation rate of the three major languages in Nigeria.
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Nice work, keep it up!
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- low dose ASA is in discussion to increase skin cancer in male adults.
- ASA showed significant decreased thymus-size in animal studies.
- Should we create studies to clear this question ?
Is their any data in neonates or children after longterm low dose ASA in pregnancy?
In Germany we observe an uncritical use of low dose ASA in reproductive medicine and every kind of previous pregnancy complication.
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For me is a doubt, if toddlers (1-2 years old) work with the atelierista. I know that in the next stages the atelierista is a important teacher, but infants visit the atelier too?
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From the infant toddler stage so very young, I think that the first documented pieces start at about 2 yrs of age. I would have to check it up though. I am sure they have a permanent atelierista that works across the classes from 0 to 3 yrs.
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Our plan is to enroll all babies born in a particular district and follow them up until 1 year old. We expect about 38000 births in the district and about 70 cases. Sample size calculators are giving me a sample size of 1! How do I go about it?
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another potential useful source, pdf free available.
i assume that you simply want an accurate estimate of the incidence ?
Sample size estimation in epidemiologic studies
Karimollah Hajian-Tilaki, PhD*
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By birth many of the infants are affected by congenital glaucoma. What is the main reason behind this and could this possible to find the symptoms in earlier stage?
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Remnants of mesodermal tissue in the anterior chamber angle causing resistance to aqueous humor outflow resulted in increased IOP causing optic nerve atrophy and opacification of transparent cornea , enlarged globe due to elasticity of sclera -buphthalm. Management-surgery goniotomy
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I need to buy a portable HRV monitor to assess vagal tone in infants during several experiments.
I am looking for a new device since the one cited in the studies are mostly old.
Any suggestions?
Thanks a lot
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Thank you all! your suggestions were very helpful
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I am a research student at my institute for 6 months and I am going to work on research project entitled "detection of reasons behind infant cry". For this project, I need a database which will have the audio files of crying babies with reasons specified. Are there any such databases available?
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yes, for sure, we have data during venous puncture, as published
Assessment of pain expression in infant cry signals using empirical mode decomposition.
Mijović B, Silva M, Van den Bergh BR, Allegaert K, Aerts JM, Berckmans D, Van Huffel S.Methods Inf Med. 2010;49(5):448-52. doi: 10.3414/ME09-02-0033. Epub 2010 Jun 22.
PMID: 20582383
Decoupling between fundamental frequency and energy envelope of neonate cries.
Silva M, Mijovic B, Van den Bergh BR, Allegaert K, Aerts JM, Van Huffel S, Berckmans D.
Early Hum Dev. 2010 Jan;86(1):35-40. doi: 10.1016/j.earlhumdev.2009.12.006. Epub 2010 Jan 22
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I would like to carry out a long-term study on infants (from 3 to 12 months of age). I have invented a simulation: The Infant Learning Environment Program. It puts infants in control of the program from their first interaction with it. Its goal is to simultaneously teach infants to speak, read, and think.
If interested, please read Inventing an Infant Learning Environment that can be downloaded from thinkingbabies.org and Research Gate.
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If they could help that would be wonderful. I will try but so far no non-profit agrees with my approach. Thanks.
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I use a craniometer daily to measure infants with plagiocephaly and/or brachycephaly. It is not easy as infants do not always cooperate, but I think it work well after some training (if using a headband with marks). This weekend I had inexperienced therapists (inexperienced in measuring with craniometer) measuring models of infant head ("home made"), it ought to be rather "easy" as this model heads do not move. However the result was not as good as expected, (I will do it again with better models of heads).
I would like to know about others experience with measuring with craniometer.
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I use it everyday in my daily practice and it helps a lot to monitor my babies asymmetries.
of course it does not allow a volume assesment but it gives us a great idea of what is going on.
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Role of ultrasound in developmental dysplasia of the infants hip (DDH) joint very informative and valuable before 6 months infants age.
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some other potential useful references:
Screening in Developmental Dysplasia of the Hip (DDH).
Paton RW.
Surgeon. 2017 Oct;15(5):290-296. doi: 10.1016/j.surge.2017.05.002
How to use… Hip examination and ultrasound in newborns.
Collins-Sawaragi YC, Jain K.
Arch Dis Child Educ Pract Ed. 2018 Feb;103(1):34-40
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I would like to know how adults' varied nerve fibers influence the way infants respond to their touch.
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Hi, Karel. Thank you. That's actually what I'm not sure about. If the nerve fibers refer to the thickness of hair in a person providing the touch or whether every person really has nerve fibers that differ from the rest..
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May I know is there anyone who have experiences on infants (0-4 months of age) saliva collection and analysis who can share?  I am wondering what factors should I consider before I choose which kits to go for? Do I really need to use a kit? PM or comment are welcome. 
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Hi Karel, thanks for the answer, may I know did you use Protease Inhibitor Cocktail in your samples?
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In the NICU population, does dressing and swaddling infants on air mode in an isolette help wean and adjust to open crib better than dressing and not swaddling infants? 
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the easiest and most open answer is we don't really know and practices vary. A warm open bed may be an approach to wean from an isolette, and i do recommend to follow the weight gain/evolution throughout the weaning.
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I would like to find the guidelines for the indoor air quality parameters such as:
- Temperature
- Relative Humidity
- Formaldehyde
- PM
...
not for adults but for infants.
Are there any references ?
Thanks
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What changes occur when an infant and subsequently child first realize that they are "different" than "you." What might be missing (neurophysiologically) in some autistic spectrum individuals when they refer to themselves as "you"?
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Except when the symptom picture looks like celiac disease and yes taste is a sensory function, which is impaired in most autistics. If so many systems are involved then one would imagine that there was something central to all of it and labyrinthine mechanisms are not it - but part of something underneath it all. But, back to my original question which was not about autistics but all of us. What neurophysiological changes are associated with the emergence of self-identity, if any? Does body image à la Henry Head have anything to do with this?
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Mother's own milk is preferred nutrition for a premature infant. Mother's own milk delivered "fresh" or not ever frozen has been consistently shown to have higher nutritional content and retain more immune-protective factors. However delivering fresh milk to bedside proves to be a systems-based challenge in large units. Some large children's hospitals have processes to routinely freeze all milk upon entry. Does your neonatal intensive care unit consistently deliver fresh milk to your infant when available? 
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Our NICU offers only fresh mother's milk for preterm babies. We have a organized place for extraction, the newest fresh milk is always offered on same day. The excess is first refrigerated and if not used, only then it is frozen. We are currently analyzing data comparing pasteurized human milk and mother's own fresh milk and expect to publish some answers by the end of this year.
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Are there any fundus findings in an infant when there is increased intracranial pressure?
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infants' fontanele is still open and their bones are elastoc, so any increase of intracranial pressure will be compensated by enlargement of head circumference until one point where they can not compensate any longer. it is then when you may find papiledema.
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We would like to either calculate CDI for different monthly periods after birth or for period of 1 year after birth for measured POPs concentrations in human milk. Would you recommend to use a traditional risk assessment approach for calculation of CDI, thus “CDI = C x IR x EF x ED / BW x AT” or would you alter the equation in some way? There are articles using just the following equation “CDI = C x IR / BW” however they do not take into account length of exposure and they produce significantly different results.
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Hello Anna. I read your question and wondered if the use of the traditional risk assessment approach is the best means of addressing the issue. It's not completely clear to me from your question what you would like to achieve by calculating the risks, but I would emphasise that using the risk assessment approach you mention will probably give you very conservative estimates of risk related to these chemical exposures. I would highly recommend that if you want to calculate realistic (i.e. non-conservative) estimates of risk, you should consider using epidemiological data to support your assessment i.e. calculate the attributable risk associated with exposure to these POPs using odds ratios (or relative risks) from epidemiological studies. Although the exposures and outcomes are different, I wrote a paper about how and why to use epidemiological data in support of risk assessment. I hope it's helpful.
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i am working on infant cry detection system, i want to detect infant cry by facial
expression, so what are features of the image i should extract to do with deep
learning algorithms. how it is done?
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The biggest advantage of Deep Learning is that we do not need to manually extract features from the image. The network learns to extract features while training. You just feed the image to the network (pixel values).
What you need is to define the Neural Network architecture and a labeled dataset.
In your case you need a set of images and, for each image, you need to know if the person is crying or not.
For the NN architecure, you can choose a standard architecture such as VGG, GoogleNet or ResNet.
You should consider using a network that was trained on a large dataset (ImageNet) and finetune it to your application. This is called Transfer Learning and you can see some examples here: https://keras.io/applications/
I strongly advise you to spend some time learning about Machine Learning/Deep Learning. There are some good online courses (Coursera, CS231N) that will help you get started. Also, I would advise you to read some papers on the subject.
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I am a health visitor, and get asked about treating sticky eyes in infants a lot. Another practitioner has recommended treating this with baby shampoo. I am not happy to recommend this treatment as i am unaware of any research that supports
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I will never suggest such management. Make sure it is not due to nasolacrimal duct obstruction which I remember eye doctors suggest to use gentle pressure over the  puncta to pump it open.
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Powdered infant milk formula treated with electron beam sterilisation.
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We have already reported such a case in an infant. You can find the link in my profile.
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Dr. Sivakumaran, I have gone through all the cases reported till now. The problem is nobody has made any consensus regarding this topic.
But anyways , thank you for your opinion.
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I want to measure TEWL in extremely premature infant's nursed in high humidity.
I'm not sure if the existing devices to measure TEWL are accurate in high humidity.
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Dear, I have no knowledge.
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Dear colleagues,
I am looking for research on the experiences of moms of preterm born infants regarding child care in the first year. I would apreciate if you can share or indicate literature on this topic, since I am not finding it. Thanks a lot. Regards
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Dear Robert,
yes, I meant alternative caregivers. There is some literature available, although it does not address the experiences of the mothers about choosing the type of care for the infant born prematurely. I will take a look on this website. Regards,
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I was wondering if you could help me to understand the score awarded by PEDro to my article on the "blind subjects" criteria. Here is the link to it: http://search.pedro.org.au/search-results/record-detail/37529
Were the infants of the study considered to be blind because the envelopes were opened right immediately before the training session, which was a brief and single one and therefore it unabled them to distinguish between the treatments applied to the other groups? This question is because most of the other articles in which infants' reaching was trained (training over weeks, not in a single session) did not awarded the "blind subjects" criteria. I really would like to understand how that criteria works for infants.
Thank you in advance.
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Hi Daniele, 
I understand the PEDro summary differently: "Blind subjects: No; Blind therapists: No" - so neither the study subjects nor the therapists/providers were considered to be blinded. 
Best, 
Helena
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Does anyone know of research that indicates that young infants (i.e., 8-15 weeks) might process adult and other infant faces differently in any way?
Thanks,
Siobhan
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Have you checked Viola Macchi's research? She found an "other age effect" from 9 months of age if I am correct
yours
Olivier
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I want to start working in a kindergarten and I need some idea to doing some tests about creativity and acting out (discharge, purge) in children, for example, painting.
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Over the past few years working with young children I have found the Behavior Rating Inventory of Executive Function (BRIEF) measures very helpful (See: PARinc for details).  Although designed with attention deficit disorders in mind, I use the instruments to help analyze overall behaviors rather than simply determining some disorder/disability. I have found them especially useful in the context of highly able children whose behaviors are often situation dependent. The information helps me determine, for example, whether elevated 'shift' ratings are noted by a teacher/s and, or a parent /s,; whether or not  the 'inhibit' and 'working memory' ratings provided from home and, or school are similarly elevated, whether elevated ratings for  'emotional control' are provided by one particular person, e.g., mother, father, teacher or teacher's assistant.
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There was some beliefs between parents that teething can cause wheezing.
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During teeting children can get a stuffy nose, but a wheeze should not be present. When babies "cut" teeth an inflamitory process is set up. The gums become irritated and this can lead to a fever and other cold like symptoms. also when ever a babies immune defenses are challenged as you see when they get new teeth it allows other germs to gain access to thier developing immune system and they become more suseptable to cold viruses and other illnesses. I hope this helps. Dose him with tylenol and if you Dr. says it's ok with Motrin as tylenol won't help the inflamation of his gums and the motrin will. Keep his room well humidified and you could use some saline in his nose to help loosen secretions and that will allow them to drain out a little more easily. If he continues to wheeze you should get him to the Dr. as this could be signs of a true illness.
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I want to know the name of the questionnaire i can use to measure caregiving experiences with infants . 
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The one I see used the most often is the Baby Care Questionnaire.  I have attached an article that specifically discusses the instrument.
  Note - If you search on "caregiver" instead of "infant care" or "baby care," you will find a huge number of questionnaires that measure the experiences of adults taking care of other adults.
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Microcephaly is a rare side effect in these cases. I need to know exactly how rare.
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You should retract that assertion as it may be libelous.I am simply trying to get an answer to a medico-legal question
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The tool will be used for evaluation of infants typically seen in Level 1 nursery.
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Ballard Scoring
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Dear colleagues, does anyone know an article about bone mineral content (BMC) in newborn and adults (changes through age)? I just found, for example, BMC in lumbar spine of infants, but no comparison to older ages.
Thanks in advance!
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Thank you very much, Mustafa!
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I am looking at research on infants ability to speak and whether or not teaching an infant sign-language can help develop their verbal ability.
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You may consider looking into research on bilingualism and the cognitive and language benefits that come from learning two languages. Sign language does count as another language so looking into research on bilingualism may be a good place  to start.
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I would like to know about the infection control risks of readmitting infants to the newborn nursery following discharge.
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Hello Deeann, I believe that very often the decision has to be made depending on weighing up the risks to those who have been discharged, as well as the risks of all the occupants in the nursery.  In some places, there may be alternative areas assigned to babies that still have the infection, and those that are on the road to recovery. (In some places, the availability of nurses to care for them is also another need to be considered.)