Science topic
Ibogaine - Science topic
One of several indole alkaloids extracted from Tabernanthe iboga, Baill. It has a complex pharmacological profile, and interacts with multiple systems of neurotransmission. Ibogaine has psychoactive properties and appears to modulate tolerance to opiates.
Questions related to Ibogaine
hello,
we are working to find already known naturally occuring plants, funghi, microbiota and the like, showing gabapentinoid activity or aiding the effect or helping with the reduction and so forth in order to support the tapering of pregabaline and similar substances and helping to rebuild normal functionality after the cessation.
it doesn't need to be exclusively focussed on gapapentinoid modes of action as there is probably a plethora of possibilities to start inducing a slow and protected adaptation of receptor density and Gaba supply and to heal the other affected metabolic and functional cycles in order to meet the demands placed by sobriety on the brain's constitution.
i'm thinking for example of the modes of action of ketamine and ibogaine and other nmda antagonists.
also, which minerals and vitamins need to be primarily replenished (like b1, b5, b6, b7 b11, b12,...) and which nutrients or active substances (like taurine or magnesium,..) do aid the restoration process?
we also look forward to all lifestyle recommendations like living free of stress, regular exercise, ...
we welcome any input, ideas, hints, papers and research and hope together we can help a many good people who stumbled into a miserable situation!
thank you all in advance,
patrick schimpl
chairman of project: kindergarten, non-profit organisation, 'because if the world's a garden for children it's paradise'
