Hormones - Science topic

About the 47th Symposium on Hormones and Cell Regulation G protein-coupled receptors (GPCRs) are encoded by the most important gene family in the human genome, representing 3% of the protein coding genes (820 genes).

Introduction: Bisphenol A (BPA), as an endocrine disruptor, found in packaging materials for food and drugs is of public health concern. It accounts for the majority of daily human exposure. Health problems associated with BPA exposure in humans includes reproductive issues, changes in hormone levels and various cancers. Recognized therapeutic effe...

A Insuficiência Ovariana Prematura (IOP) é uma condição endocrinometabólica caracterizada pelo esgotamento prematuro da reserva folicular ovariana antes dos 40 anos, acometendo aproximadamente 1% das mulheres em idade reprodutiva. As intervenções terapêuticas convencionais, como a terapia de reposição hormonal (TRH), atenuam os sintomas do hipoestr...

Dalam dunia kesehatan reproduksi, Keluarga Berencana (KB) memiliki peran krusial dalam meningkatkan kesejahteraan masyarakat. Buku Merancang Masa Depan: Panduan Praktis Keluarga Berencana dan Kontrasepsi untuk Bidan hadir sebagai panduan komprehensif bagi bidan dan tenaga kesehatan dalam memahami serta menerapkan program KB secara efektif. Buku ini...

O câncer de pulmão é a neoplasia de maior mortalidade no mundo inteiro. Além do seu grande impacto na sobrevida, a presença de síndromes associadas diminui drasticamente a qualidade de vida dos pacientes. A Síndrome da secreção Inapropriada do Hormônio Antidiurético (SIADH) é considerada uma síndrome paraneoplásica do Carcinoma Neuroendócrino de cé...

Psychedelics have demonstrated promising potential in treating mental health conditions like depression, anxiety, and PTSD 8. Although women are more likely to suffer from such conditions 9 , sex differences in the effects of these substances remain largely unexplored.

El hiperparatiroidismo en pacientes con enfermedad renal crónica (ERC) se denomina hiperparatiroidismo secundario (HPTS), y se caracteriza por niveles elevados de la hormona paratiroidea debido a hiperfosfatemia, hipocalcemia, niveles bajos de vitamina D derivados del deterioro de la función renal. Por lo tanto, el objetivo de este estudio fue dete...

Background: Sjögren's syndrome (SS) is a variety of autoimmune inflammatory conditions distinguished by lymphocytic glandular invasion and various extra-glandular manifestations. SS is most likely seen in middle-aged females. Immunological, viral, genetic, ecological, and hormonal etiologic aspects are dubious regarding the etiology of SS, and no a...

Vitamin D(VD), which is accepted widely to function as both a hormone and a vitamin, plays a crucial role in maintaining normal physiological processes. Its potential to mitigate disease severity has garnered significant scientific interest. Studies across various cell lines, animal models, and human populations have highlighted its extensive prote...

Khaya grandifoliola, conhecida popularmente como mogno africano, destaca-se como uma importante espécie florestal, amplamente utilizada no setor movelaria e construção civil. O presente trabalho teve como objetivo avaliar a influência de BAP e tempo de cultivo na multiplicação in vitro de Khaya grandifoliola, utilizando segmentos nodais. Testou-se...

Buku ini dirancang sebagai panduan pembelajaran komprehensif bagi mahasiswa kebidanan dan bidang kesehatan lainnya dalam memahami sistem reproduksi manusia. Dimulai dari anatomi dan fungsi organ reproduksi, proses fertilisasi, kehamilan, hingga persalinan dan perawatan bayi baru lahir, modul ini menyajikan materi secara sistematis dan mudah dipaham...

Physiological and agricultural uses of hormone cytokinins

Bu kitap bölümü, insan mikrobiyotasının özellikle bağırsak, vajinal, endometriyal, testiküler ve seminal bölgelerdeki dengesinin, üreme sağlığı üzerindeki kritik etkilerini vurgulamaktadır. Mikrobiyal dengenin bozulması (disbiyoz), hormonal düzensizlikler, inflamasyon, oksidatif stres ve bağışıklık yanıtları yoluyla hem kadın hem de erkek infertili...

Kosmetik alami semakin populer karena produksinya yang luas oleh sejumlah industri terkait kosmetik. Salah satu produk yang paling umum digunakan untuk merawat rambut adalah sampo. Untuk menjaga rambut tetap bersih dan sehat, kita dapat menggunakan produk yang disebut sampo. Kerontokan rambut dapat disebabkan oleh banyak faktor, termasuk genetika,...

Enhancement of development competence of immature cattle oocytes supplementing culture media with triiodothyronine and thyroxine hormones

The increasing global burden of cancer necessitates innovative approaches to prevention and treatment. Lifestyle factors such as diet, physical activity, and smoking significantly contribute to cancer. At the same time, current guidelines are based on a one-size-fits-all approach, which limits their effectiveness across diverse populations. Obesity...

Asthma is a prevalent chronic condition, affecting an estimated 260 million people worldwide, according to the 2021 Global Burden of Disease Study. This condition significantly impacts individuals of all ages. One notable finding is that asthma prevalence among adults was higher in females than males. Recent evidence suggests that these disparities...

Gynecomastia is a benign proliferation of the glandular tissue of the male breast. It is a common physiological condition during infancy and puberty and typically resolves spontaneously in most cases. However, adult-onset gynecomastia requires proper evaluation to identify the underlying cause. Several medications are associated with gynecomastia i...

As dislipidemias contribuem para que as doenças ateroscleróticas sejam a primeiracausa de óbitos no mundo, incluindo o Brasil. O excesso de peso também é um fatorcontribuinte significativo nesse contexto. Sendo assim, o Ministério da Saúde institui,por meio da Portaria Conjunta nº 8, de 30 de julho de 2019, a aprovação do “ProtocoloClínico e Diretr...

A eficiência dos protocolos hormonais na superestimulação de ovinos é fundamental para a reprodução e a biotecnologia da produção in vitro de embriões. Este estudo comparou a eficácia do FSH (Hormônio Folículo Estimulante) e do eCG/PSMG (Gonadotrofina Coriônica Equina) na resposta ovariana e nos desfechos reprodutivos de ovelhas Dorper. Foram utili...

O câncer de mama (CA) é uma etiologia multifatorial e prevalente em todo o Brasil, influenciada pelos fatores externos e internos. Aliás a prevenção do CA é um fator importante para o combate e redução da prevalência da doença, além disso, a equipe multidisciplinar tem um importante papel para o combate e controle do CA. O objetivo do nosso trabalh...

Introduction. L'endométriose thoracique est l'ectopie de l'endomètre au niveau du thorax. La forme la plus fréquente est le pneumothorax cataménial qui représente environ 75%. L'hémothorax endométriosique est une forme peu fréquente excep-tionnellement compliqué d'un hémopneumothorax. Les auteurs rapportent une nouvelle observation d'un hémothorax...

Dr. Correo Hofstad's groundbreaking discovery of a quaternary coding system revolutionizes our understanding of hormonal communication, linking cortisol, memory, and DNA in unprecedented ways. Explore the significance of these findings for human health and intelligence.

PURPOSE: This study aimed to investigate the influence of sex, age, and body condition on the prevalence and intensity of ectoparasitic infestations in goats, focusing on lice and fleas, and to identify significant associations between these factors. METHODS: The study was conducted on 4,599 goats examined between May 2018 and November 2019. The an...

Here, we described the most common reported tools to analyze the internal training load in four individual sports (tennis, combat sports, weightlifting and triathlon), mitigating the injury risk and control fatigue and stress. Hormonal analyzes has been shown to be a good predictor of weightlifting performance in a training/competition. In combat s...

El objetivo fue evaluar el efecto de la hormona foliculoestimulante (FSH) y la somatotropina bovina (bST) sobre la dinámica folicular en vacas lecheras lactantes y no lactantes. Se realizó un ANOVA factorial 2x2, considerando el estado de lactancia y la hormona utilizada como factores. Se utilizaron 20 vacas, 10 lactantes (5 con FSH y 5 con bST) y...

At the core of adaptive behavior is the ability to accurately predict relationships between environmental events. Such predictions require associative relationships to be updated in the face of changing contingencies. One example of such updating is the overexpectation effect. Prior investigations into overexpectation in the appetitive domain revea...

Objetivo: Analisar a influência do estresse do retículo endoplasmático (RE) e da resposta a proteínas mal dobradas (UPR) no diabetes tipo 2. Métodos: A pesquisa foi realizada nas bases de dados PubMed, Wiley Online Library e Embase, com a combinação dos descritores MeSH “Diabetes Mellitus, Type 2”, “Endoplasmic Reticulum”, “Unfolded Protein Respons...

"The five S's of sports training are: stamina, speed, strength, skill, and spirit; but the greatest of these is spirit." (Ken Doherty) Both sports endocrinology and exercise physiology deal with the body's response to physical activity, but they focus on different aspects. The presented references expand upon the foundational knowledge of sports en...

Background Melasma is a common hyperpigmentation disorder that causes significant distress to patients. In the real world, it is closely associated with various medications, making the timely identification and discontinuation of causative drugs an important aspect of clinical management. This study investigates the relationship between melasma and...

A razão deste artigo é revisar a literatura existente sobre a predominância estrogênica e o manejo nutricional, salientando os principais fatores que contribuem para essa condição e as estratégias nutricionais recomendadas para seu tratamento com enfoque a saúde da mulher. A predominância estrogênica se dá quando os níveis de estrogênio no corpo sã...

El ciclo reproductivo equino presenta irregularidades en el desarrollo folicular, ya que el celo dura entre 5 y 7 días, dificultando determinar el momento exacto de la ovulación. Por ello, este estudio evaluó el crecimiento folicular diario inducido por acetato de gonadorelina (GnRH) en 16 yeguas de Paso (4–14 años). Se inició la monitorización eco...

La salud colectiva ha aportado perspectivas analíticas de gran riqueza para comprender la determinación social de la salud y cómo las dinámicas de desigualdad, inequidad e iniquidad son productoras de padecimientos, enfermedades, morbilidad y mortalidad. Desde esta mirada, en este trabajo se identifican y analizan modalidades de apropiación y uso d...

Background Since the introduction of the birth control pill in 1960, Canadians have been offered a number of different options for hormonal contraceptives, yet oral contraceptives remain the most popular methods. Research from other countries indicates this may be shifting, but the last comprehensive survey of Canadian hormonal contraceptive usage...

Background: Measuring quantitative menstrual cycle hormones at home may help women better understand their postpartum and perimenopause fertility transitions, but these quantitative fertility monitors require validation. Materials and Methods: This study included 16 North American women, aged 28–51, during either the postpartum (n = 8, cycles = 18)...

Introduction: Papanicolaou smear is a widely used method for diagnosing precancerous and cancerous lesions, estimating hormonal status and the presence of possible infections, and is the only method used in cervical cancer screening programs. Since the number of samples to be evaluated in these national programs is very large, it is necessary to re...

The biological basis of behavior refers to the physiological and biochemical processes that influence how organisms act. Key factors include brain structure and function, neurotransmitters, hormones, genetics, and early development. The nervous system plays a central role, with neurons transmitting signals that regulate movement, emotions, and cogn...

Chronic Kidney Disease CKD berdampak pada penurunan kualitas hidup, memperbesar pengeluaran secara finansial serta kondisi paling fatal yakni kematian dini. Hemodialisis merupakan suatu terapi yang dapat memperpanjang harapan hidup pasin CKD, tetapi proses Hemodiallisis ini berdampak pada kecemasan pada pasien CKD. Desain penelitian yang digunakan...

Musik telah lama dikenal sebagai alat yang efektif dalam mendukung kesehatan mental, terutama dalam meredakan stres dan kecemasan. Artikel ini membahas bagaimana musik dapat digunakan sebagai terapi yang membantu meningkatkan kesejahteraan emosional melalui mekanisme psikologis dan neurologis. Musik mampu menurunkan kadar kortisol, meningkatkan pro...

Vitiligo vulgaris is an acquired disorder that is thought to arise from the suppression of melanin synthesis by melanocytes in the basal epidermal layer. To develop therapeutic agents for vitiligo vulgaris, it is critical to identify compounds that promote melanization. In this study, we established a digital image-based method to quantify melaniza...

La insuficiencia ovárica primaria (IOP) es un trastorno caracterizado por hipogonadismo hipergonadotrópico y disfunción ovárica antes de los 40 años. Mutaciones inactivantes del receptor de FSH (FSHR) afectan la transducción de señal, generando resistencia ovárica a gonadotropinas. Esto interfiere con la foliculogénesis y la producción estrogénica,...

Congenital adrenal hyperplasia (CAH) is a rare but significant medical disorder that affects the adrenal glands, causing excessive production of androgens, a group of hormones responsible for the characteristics associated with male sexual development. CAH can present in a variety of forms, with one typical clinical presentation being clitoromegaly...

Purpose To examine the natural history of focal nodular hyperplasia (FNH) lesions through long-term ultrasound (US) follow-up and assess the relationship between clinical characteristics and size changes. Methods We retrospectively enrolled 55 patients diagnosed with FNH who were followed with ultrasound for at least 24 months. A total of 94 FNH n...

Kegagalan dalam proses menyusui sering kali disebabkan oleh berbagai masalah, salah satunya adalah kurangnya produksi ASI. Namun, produksi ASI yang tidak lancar dapat diatasi melalui beberapa cara, seperti mengonsumsi buah pepaya (Carica papaya L.) dan melakukan pijat oksitosin. Pijat oksitosin berfungsi untuk merangsang refleks oksitosin, yang tid...

Bawang merah (Allium cepa L.) merupakan salah satu tumbuhan yang berpotensi untuk digunakan sebagai zat pengatur tumbuh alami, karena bawang merah mengandung hormon auksin yang dapat memacu pertumbuhan akar pada tanaman selada. Percobaan lapangan dilaksanakan di Kebun Fakultas Pertanian Universitas Winaya Mukti, Kecamatan Tanjungsari, Kabupaten Sum...

As an efficient management pattern to improve logistics efficiency through intensive management of construction materials, construction logistics centers (CLCs) have received active attention from academics and practitioners. However, the CLC location–allocation problem, which considers periodic demand and transportation risk, has not been adequate...

Die Wechseljahre sind eine Le-bensphase, in der der weibliche Kör-per tiefgreifende hormonelle Verän-derungen durchläuft. Diese Umstel-lung bringt nicht nur klassische Symptome wie Hitzewallungen und Stimmungsschwankungen mit sich, sondern kann auch die Augengesund-heit erheblich beeinträchtigen (1). Dennoch bleibt dieser Aspekt häufig unbeachtet....

The work examines the causes and provoking factors of the occurrence of autoimmune thyroiditis , which are associated with the human hormonal system. It is shown that cervical dysbacteriosis changes the immune response, which leads not only to high exposure to antigens, but also to local inflammation.

This ecological momentary assessment study in daily life highlights that women’s alcohol craving compared to men decreases over time and is influenced by menstrual phases. This has important implications for personalized Alcohol Use Disorder treatments, that may benefit from considering gender and sex-specific factors such as hormonal cycles.

Kambing Peranakan Ettawa (PE) merupakan salah satu aset sumberdaya genetik ternak (SDGT) lokal Indonesia yang sangat penting untuk dilestarikan dan dikembangkan agar diperoleh manfaat produksi yang bernilai ekonomis. Tujuan dari studi ini adalah untuk mengetahui faktor-faktor apa saja yang mempengaruhi produksi ternak Kambing Perah di Kabupaten Sle...

Objetivo: conhecer as experiências das mulheres na sobrevivência do pós-tratamento do câncer ginecológico. Método: estudo qualitativo, desenvolvido com vinte e cinco pacientes do Instituto Nacional do Câncer, com dados coletados entre fevereiro e abril de 2022, por meio de entrevistas norteadas por roteiro semiestruturado. As falas foram analisadas...

Introduction: Gynaecomastia is the most common benign condition of male breast. It is characterized by hyperplasia of ductal tissue, stroma and fat cells. Commonly it occurs at infancy, adolescence and old age during the time of hormonal changes. Rarely it is associated with testicular tumours, liver diseases and medications.To study the outcome of...

353 hospitalized children diagnosed with Mycoplasma pneumoniae (MP) pneumonia were included in the study. They were divided into MP co-infection group and MP single infection group. 143 (40.5%) of the enrolled children had MP co-infections. The most common co-infecting pathogen was Rhinovirus (30.8%). Among the MP co-infections, 82 cases (57.3%) in...

Introducción: la hiperplasia suprarrenal congénita engloba un espectro de anomalías enzimáticas de herencia autosómica recesiva, donde se encuentra ausente o deficiente una de las enzimas necesaria para la síntesis de cortisol y aldosterona. La deficiencia de la 21 hidroxilasa es la causa más frecuente y su presentación más severa es la forma clási...

Background Human epidermal growth factor receptor 2 (HER2)-negative operable breast cancer (BC) patients with germline BRCA1/2 pathogenic variants may benefit from adjuvant olaparib treatment. However, data about how many patients were eligible for olaparib treatment in operable BC patients with BRCA1/2 variants after neoadjuvant chemotherapy (NACT...

Introducción: Diversos estudios han puesto de manifiesto que los preparados del fruto de hinojo (Foeniculum vulgare Miller) pueden ser útiles para aliviar los síntomas asociados a la menopausia. El objetivo de este trabajo es realizar una revisión de los artículos publicados sobre la eficacia y la seguridad del hinojo en el tratamiento de los sínto...

The effect of kisspeptin preparation on the expression of the genes of hormonal regulation of sexual behavior in Danio rerio fish was studied after the effect of social isolation. For this, fish were placed in individual containers for 48 h to model the conditions of social isolation, after which kisspeptin was administered, and they were again pla...

O envelhecimento cutâneo é um processo multifatorial influenciado por mecanismos intrínsecos e extrínsecos. Diversas teorias explicam esse fenômeno, incluindo a teoria dos radicais livres, que atribui o envelhecimento ao estresse oxidativo causado pelas espécies reativas de oxigênio (EROs); a teoria genética, que destaca o encurtamento dos telômero...

APRESENTAÇÃO. -- A despeito do sexo genético que herdam, os mamíferos iniciam a vida embrionária em uma rota sexualmente neutra. É a presença do cromossomo Y que promove o desenvolvimento dos testículos. Estes, por sua vez, liberam hormônios que fazem com que os tecidos do corpo sigam a rota masculina. Na ausência do cromossomo Y, os testículos não...

Objetivos Medir la calidad de vida de mujeres supervivientes de cáncer de mama (CM) y detectar diferencias en función de variables clínicas y sociodemográficas. Diseño Estudio observacional transversal de mayo a agosto de 2024. Emplazamiento España. Participantes Mujeres supervivientes de CM, seleccionadas por muestreo intencional no probabilíst...

Zusammenfassung Endometriose bildet sich nach der Menopause (postmenopausal) in der Regel zurück, jedoch zeigen sich bei 2–5 % der postmenopausalen Frauen persistierende Beschwerden oder Rezidive nach Hormonersatztherapie (HRT). Für diesen Artikel wurden eine Umfrage unter Gynäkologen zum Wissensstand über HRT und Endometriose sowie eine Literaturr...

Introduction: Dental caries is hereditary and excessive caries run in households and are passed from mother to baby and run along generations. The early and correct detection and analysis of dental caries is a crucial thing for the general control of the dental patient. Presently, the so-called hormonal fingerprint additionally known as 2D:4D ratio...

Pyogenic granuloma or granuloma pyogenicum or pregnancy tumor is a well-known oral lesion which is a fast growing reactive proliferation of endothelial cells mainly seen on the gingiva. It usually arises in response to various stimuli such as traumatic injury, local irritation, hormonal factors, or certain kinds of drugs. This article presents a de...

Male breast cancer is infrequently seen, representing less than 1% of all breast cancer cases and less than 1.5% of all cancers in men. Because of a lack of awareness, it leads to late presentation and diagnosis. Because of its rarity, very little is known about its risk factors, including hormonal and genetic anomalies. According to certain resear...

Purpose: The purpose of this study was to assess the relationship between the radiological criteria determining an primary empty or primary partial empty sella and the pituitary hormone levels. Methods: Out of 594 patients who underwent pituitary magnetic resonance imaging (MRI), we selected 43 patients with primarily empty and partial empty sella...

In the realm of pediatric urology, varicocele stands as a common yet contentious issue due to its possible impact on future fertility. The crucial points of contention involve the difficulties in detecting at-risk children early on, determining the best time for intervention, and selecting the most suitable treatment methods. This extensive review...

يُعنى هذا البحث بدراسة موضوع استعجال البلوغ بالوسائل الطبية قبل أوانه، والمراد: استعجاله في السن المعتاد للبلوغ وما قبله أيضاً، قبل ظهور علاماته المعتبرة شرعاً وطباً، ويؤكد البحث أن مناط التكليف الشرعي هو العقل، وأن الرأي الفقهي والطب الحديث يتفقان على أن العلامات الجسدية للبلوغ مقارنة عادة لاكتمال العقل، وبالتالي يُمكن اعتمادها أمارة عليه، نظراً ل...

Cortisol is a key hormone involved in stress responses, and its regulation can vary across populations experiencing different environmental pressures. While short term changes in certain environmental factors can result in immediate changes in cortisol levels, it remains unclear whether variable and fluctuating environments affect lifetime stress r...

Sectio caesarea merupakan metode persalinan melalui pembedahan dinding abdomen. Salah satu efek samping dari luka sectio caesarea adalah nyeri persisten. Nyeri yang dirasakan oleh ibu akan membuat ibu merasa tidak nyaman sehingga akan mempengaruhi produksi ASI. Produksi Asi yang tidak lancar dapat ditingkatkan dengan konsumsi nigella sativa. Nigell...

There is a growing need for dental treatments in women during the puerperal period as a consequence of hormonal and physiological changes that occur. There are effective methods that dentists can apply while treating patients in the puerperal period and while ensuring the maintenance of treatment. The framework of these methods covers a wide range...

O trabalho utilizou os reguladores de crescimento, giberelina e citocinina, com o objetivo de melhorar a emergência e o desenvolvimento das plântulas. Esses desempenham papéis cruciais em vários processos fisiológicos das plantas. A giberelina promove a germinação e crescimento, além de promover o alongamento do caule. A citocinina é um hormônio ve...

A giberelina é um fitohormônio produzido nas sementes, atuando no crescimento e acelerando a emergência de plântulas, com maior produção de massa. Est pesquisa foi realizada com o objetivo de avaliar o efeito da giberelina na emergência e desenvolvimento de mamão cultivar aliança. O experimento foi conduzido no viveiro de produção de mudas do IFES-...

Introdução: A periodontite é uma doença periodontal, de origem bacteriana, que mais frequentemente afetam e podem destruir o periodonto. A menopausa ocorre apenas nas mulheres e é definida como amenorreia que dura mais de 12 meses consecutivos, acompanhada de uma falta de estrogênios que pode conduzir à osteoporose. A osteoporose é definida como um...

As pesquisas com reguladores de crescimento como giberelina e citocinina, são realizadas para identificar melhoras na emergência e o desenvolvimento das plântulas. A giberelina promove a germinação e crescimento, além de promover o alongamento do caule. A citocinina regula a divisão celular e é fundamental para o crescimento dos tecidos, além de bl...

A giberelina, é uma das substâncias mais utilizadas no auxílio a germinação de sementes, pois propicia um maior alongamento do caule, aumento da divisão celular e age como promotor da germinação. O trabalho foi realizado com o objetivo de avaliar o efeito da giberelina na germinação de sementes de mamão com um ano de armazenadas, das cultivares THB...

Entre as cultivares de mamão, a aliança, formosa e taiwan aparecem com destaque no comercio nacional. Os reguladores de crescimento, giberelina e citocinina, atuam melhorando a emergência e o desenvolvimento das plântulas. A giberelina promove a germinação e crescimento, além de promover o alongamento do caule. A citocinina é um hormônio vegetal qu...

Introdução: A endometriose é uma condição ginecológica caracterizada pela presença de tecido endometrial fora do útero, que pode causar dor intensa e infertilidade. O tratamento visa aliviar os sintomas e controlar a doença, nesse contexto, os progestágenos têm se mostrado eficazes em reduzir o crescimento do tecido endometrial ectópico e a dor. Ob...

Gynecomastia or male boobs is a condition that men all over the world face. In Gynecomastia, their breast tissue develops due to an adolescent hormonal imbalance.

Cabai merah (Capsicum annuum L.) merupakan tanaman hortikultura yang banyak diminati masyarakat lokal maupun internasional dengan cita rasa pedas yang menjadi salah satu ciri khas bumbu pada berbagai kuliner. Cabai merah membutuhkan benih dapat meningkatkan produksi dan produktivitas tanaman cabai. Penelitian bertujuan untuk mengetahui pengaruh pri...

Background/Objectives: We aimed to evaluate asprosin and peptide tyrosine–tyrosine (PYY) levels in schizophrenia patients and the relationships between these levels and clinical severity, as well as whether these two hormones have a role in determining the disease and/or the phases of the disease. Methods: This study included 50 patients with schiz...

O hipogonadismo hipergonadotrófico (HH) é um distúrbio endocrinológico caracterizado pela falência gonadal primária, em que ocorre uma deficiência na produção de hormônios sexuais pelas gônadas, o que leva a um aumento compensatório dos níveis de gonadotrofinas. A puberdade tardia é um atraso no desenvolvimento das características sexuais secundári...

In most cases, unresectable metastatic breast cancer (MBC) is incurable. We report a case of bilateral inflammatory breast cancer with multiple pulmonary and distant lymph node metastatic lesions, achieving complete remission of distant metastases and curative resection of the primary lesions through combined regimen of bevacizumab, paclitaxel, and...

Objective The objective of this study was to assess the effectiveness and safety of CDK4/6 inhibitors in the treatment of hormone receptor-positive (HR+) breast cancer by using meta-analysis. Methods To gather comprehensive and reliable data for our analysis, we systematically searched multiple databases for relevant studies. We utilized RevMan5.3...

Sığır ET’nde elde edilen gebelik oranını artırmak için günümüzde pek çok girişimde bulunulmaktadır. Bu bölümde taşıyıcı sığırlarda ET başarısını arttırmak için uygulanan bazı hormon ve ilaç tedavileri ele alınmıştır. Many attempts are currently being made to increase the pregnancy rate obtained in bovine ET. In this chapter, some of the hormone an...