Science topic

Heart Diseases - Science topic

Pathological conditions involving the heart including its structural and functional abnormalities.
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Background While acute kidney injury (AKI) is a common complication in COVID-19, data on post-AKI kidney function recovery and the clinical factors associated with poor kidney function recovery is lacking. Methods A retrospective multi-centre observational cohort study comprising 12,891 hospitalized patients aged 18 years or older with a diagnosis...
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Making an accurate and timely diagnosis of cardiac disease is critical for preventing and treating heart failure. The accuracy of results produced by traditional machine learning (ML) algorithms is satisfactory. On the other hand, deep learning algorithms result in higher prediction accuracy. In this study, we used an artificial neural network (ANN...
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Objectives. To evaluate if cine sequences accelerated by compressed sensing (CS) are feasible in clinical routine and yield equivalent cardiac morphology in less time. Design. We evaluated 155 consecutive patients with various cardiac diseases scanned during our clinical routine. LV and RV short axis (SAX) cine images were acquired by conventional...
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Purpose: The main purpose of this study was to evaluate the risk of CVD mortality in the national cohort of patients diagnosed with prostate cancer and treated with ADT compared with the ADT non-users. Materials and methods: We performed a retrospective cohort study of patients aged 40–79 years and diagnosed with prostate cancer between 1 January 2...
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Cancer is associated with systemic pathologies that contribute to mortality, such as thrombosis and distant organ failure. The aim of this study was to investigate the potential role of neutrophil extracellular traps (NETs) in myocardial inflammation and tissue damage in treatment-naïve individuals with cancer. Mice with mammary carcinoma (MMTV-PyM...
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Hypertension is a well-recognized risk factor for the development of cardiovascular disease, and the early detection of cardiac changes from hypertension can allow reversing these. Hypertensive heart diseases (HHD) refer to the complex and diverse change of the cardiac structure and function secondary to hypertension. Although conventional echocard...
Article
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From March 2020 to July 2022, in Liguria region (North-West Italy) incidence of MIS-C among pediatric patients infected by SARS-CoV-2 was 38.7/100.000, which is higher than that of myocarditis after COVID-19 vaccination. In our opinion severity of MIS-C-related cardiac disease outweigh the risk of myocarditis after COVID-19 vaccine.
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As an important mechanism to maintain cellular homeostasis, autophagy exerts critical functions via degrading misfolded proteins and damaged organelles. Recent years, alternative autophagy, a new type of autophagy has been revealed, which shares similar morphology with canonical autophagy but is independent of Atg5/Atg7. Investigations on different...
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Background Laryngoscopy and endotracheal intubation may be associated with adverse events as hypertension, tachycardia, and increased serum concentrations of catecholamines. These events are serious in patients with cardiac diseases or hypertension. This work was designed to assess the effects of single dose dexmedetomidine on hemodynamic response...
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Background: While multiple cardiovascular magnetic resonance (CMR) methods provide excellent reproducibility of global circumferential and global longitudinal strain, achieving highly reproducible segmental strain is more challenging. Previous single-center studies have demonstrated excellent reproducibility of displacement encoding with stimulate...
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Women live longer than men and the absolute difference between male and female mortality risk reaches its maximum at old ages. We decomposed the sex gap in life expectancy and investigated the changes over time of the profile of the age–cause specific contributions with indicators of location, magnitude and dispersion in ten countries. Data were re...
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Background Patients using immunosuppressive drugs may have unfavorable results after infections. However, there is a lack of information regarding COVID-19 in these patients, especially in patients with rheumatoid arthritis (RA). Therefore, the aim of this study was to evaluate the risk factors associated with COVID-19 hospitalizations in patients...
Thesis
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The development of machine learning and ensemble approaches to predict and detect heart disease would be of great clinical value, but they are extremely challenging. As a result, there is a significant rate of incorrectly diagnosed cases and a lack of cardiovascular expertise in most countries. By combining analytical support for clinical decision-...
Article
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Background Acute spontaneous intracerebral hemorrhage (sICH) is a morbid and deadly form of stroke. The lymphocyte-to-monocyte ratio (LMR) and systemic immune-inflammation index (SII) are two novel markers of systemic inflammation. We aimed at investigating the predictive value of LMR and SII in patients with sICH.Methods We retrospectively evaluat...
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Objective This study aimed to estimate the prevalence of visual impairment and to identify the factors associated with it in China. Methods Data for this cross-sectional study were retrieved from the China Health and Retirement Longitudinal Study (CHARLS) for a total of 16,480 subjects who completed the questionnaire between June 2011 and March 20...
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Cardiovascular and metabolic diseases (CVMDs) are a leading cause of death worldwide and impose a major socioeconomic burden on individuals and healthcare systems, underscoring the urgent need to develop new drug therapies. Developmental endothelial locus-1 (DEL-1) is a secreted multifunctional domain protein that can bind to integrins and play an...
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Heart disease is one of the lethal diseases causing millions of fatalities every year. The Internet of Medical Things (IoMT) based healthcare effectively enables a reduction in death rate by early diagnosis and detection of disease. The biomedical data collected using IoMT contains person-alized information about the patient and this data has serio...
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Little is known about cardiovascular safety profiles for monoclonal antibody products that received the FDA Emergency Use Authorization for COVID-19. In this study, data from the FDA Adverse Event Reporting System from the first quarter of 2020 to the second quarter of 2022 were used to investigate cardiovascular safety signals associated with seve...
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The heart’s mitral valve is the valve that separates the chambers of the heart between the left atrium and left ventricle. Heart valve disease is a fairly common heart disease, and one type of heart valve disease is mitral regurgitation, which is an abnormality of the mitral valve on the left side of the heart that causes an inability of the mitral...
Preprint
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Chronic heart disease (CHD) is a common comorbidity of patients receiving endovascular aneurysm repair (EVAR) for abdominal aortic aneurysms (AAA). The ventricular systolic function determines the hemodynamic environments in aorta, and thus regulating the formation of postoperative thrombus. However, the explicit relationship between ventricular sy...
Article
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All sections of the body benefit from improved blood circulation and purification. Heart Disease's are one of leading cause of death worldwide. The some recorded symptoms, including chest pain, difficulty breathing, a rapid heartbeat,. This data is regularly examined. Healthcare regularly assesses clinical datasets through expert learning and actio...
Article
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Circadian rhythms have been identified in cardiovascular diseases, and cardiovascular risk factors can modify the circadian rhythm. The purpose of this study was to describe the onset of ischaemic heart disease symptomatology in relation to the date and time, the day of the week of presentation, the season, AMI location and severity and the level o...
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In this paper, we propose a new accelerated common fixed-point algorithm for two countable families of G-nonexpansive mappings. Weak convergence results are obtained in the context of directed graphs in real Hilbert spaces. As applications, we apply the obtained results to solving some convex minimization problems and employ our proposed algorithm...
Article
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Early diagnosis of irregular cardiac activity through existing tools such as Electrocardiogram and greater understanding of the underlying processes is critical for saving lives. Cardiac activity originates from a deterministic dynamical system of heart with trajectories following a linear map. Irregular cardiac activity observed in arrhythmia pati...
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(1) Background: The purpose of this study is to review and highlight recent advances in diagnostic uses of artificial intelligence (AI) for cardiac diseases, in order to emphasize expected benefits to both patients and healthcare specialists; (2) Methods: We focused on four key search terms (Cardiac Disease, diagnosis, artificial intelligence, mach...
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Introduction: The standard obstetric definition of fetal bradycardia is a sustained fetal heart rate < 110 bpm over at least 10 min. Fetal bradycardia can be the first and only prenatal presentation of a heart disease. We present an overview on different genetic disorders that should be taken into consideration in case of diagnosed fetal bradycardi...
Conference Paper
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Computer-aided diagnosis (CAD), a vibrant medical imaging research field, is expanding quickly. Because errors in medical diagnostic systems might lead to seriously misleading medical treatments, major efforts have been made in recent years to improve computer-aided diagnostics applications. The use of machine learning in computer-aided diagnosis i...
Article
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Recently, a growing number of epidemiological studies have examined the relationship between household air pollution (HAP) and all-cause and cause-specific mortality. While the results were not entirely consistent, the current study followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) protocol to conduct a compre...
Article
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Tetralogy of fallot (TOF) in the fetus is a typical congential heart disease that occurs during the early embryonic period, being characterized by the abnormal development of conus arteriosus. The early diagnosis and prevention of fetal TOF is very important and there is a great need for exploring the pathogenesis of it in clinic. In this study, th...
Article
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Because a cardiac function signal cannot reflect cardiac health in all directions, we propose a classification method using ECG and PCG signals based on BiLSTM-GoogLeNet-DS. The electrocardiogram (ECG) and phonocardiogram (PCG) signals used as research objects were collected synchronously. Firstly, the obtained ECG and PCG signals were filtered, an...
Article
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Covid-19 can cause disturbances in insulin production and worsen the clinical condition of patients with comorbid diabetes mellitus. In patients with diabetes mellitus, one of the complications is heart disease. Therefore, a study was conducted to determine the relationship between hs-Troponin I levels, which is a biomarker of heart disease, with t...
Article
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Patients with heart disease are more likely to experience social frailty due to physical inactivity, which may affect meaningful activities such as hobbies. This study aimed to investigate (1) the association between heart disease and social frailty in community-dwelling older adults and (2) the characteristics of meaningful activities in community...
Article
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Although brachial plexus block (BPB)-induced vasodilation reduces the incidence of arteriovenous access (AC) thrombosis, BPB cannot completely prevent its development. Therefore, we retrospectively investigated the factors affecting BPB-induced vasodilation and their effects on AC thrombosis development. Ninety-five patients undergoing AC surgery u...
Article
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Objectives To assess the differences in the management and prognosis of acute coronary syndrome in men and women who were admitted to hospital for acute coronary syndrome. Design Cross sectional study. Setting Discharge data from Swiss hospitals linked at the hospital and patient levels. Participants 224 249 adults (18 years and older) were admi...
Preprint
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1. Abstract Cardiac disease, which includes a variety of diseases that affect the heart, is a leading cause of death worldwide. One of every four deaths in the United States is due to heart disease. This means that approximately 610,000 people die from the disease each year. Heart disease is much easier to treat if detected early. Machine learning...
Article
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This work provides an opinion on palliative care for people with heart disease. The work focuses on the management of key symptoms associated with both end stage heart disease, applying a palliative approach and suggesting treatment options. The work also indicates the potential for greater collaboration of specialist teams including specialist pal...
Article
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For decades, cardiologists have largely underestimated the role of the right heart in heart failure due to left heart disease. Nowadays, the importance of evaluating right ventricular (RV) structure and function in left heart failure is well documented and this concept has been emphasized in the most recent heart failure guidelines. However, severa...
Article
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Ischemic cardiovascular diseases have a high incidence and high mortality worldwide. Therapeutic advances in the last decades have reduced cardiovascular mortality, with antithrombotic therapy being the cornerstone of medical treatment. Yet, currently used antithrombotic agents carry an inherent risk of bleeding associated with adverse cardiovascul...
Conference Paper
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Resumen Introducción y objetivos: El objetivo fue evaluar la incidencia y las causas de la muerte súbita cardiaca relacionada con el deporte (MSrD) antes y durante la pandemia de COVID-19 que comenzó en marzo del año 2019. Métodos: Se analizó la incidencia y las causas de la MSrD durante los años 2019, 2020 y 2021 a partir de la base de datos foren...
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Objective: Describe the COVID-19 death profile in the city of Rio Grande, Rio Grande do Sul, Brazil. Methods: This is a cross-sectional descriptive study using data from the Epidemiological Surveillance service deaths database of deaths notified from March to December 2020. Results: Of the 194 deaths, most were male (63.4%), aged 60 years or more (...
Article
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Maternal mortality in the United States is a public health crisis of preventable deaths among young women. The role of echocardiography in the evaluation of pregnant women with cardiovascular symptoms or risk factors without known heart disease is unclear. We retrospectively examined the clinical characteristics of consecutive pregnant patients wit...
Article
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Dyspnea in pregnancy may be due to causes other than COVID-19 infection also and these should not be ignored. Various causes include exacerbation of asthma, cardiac illnesses, severe anaemia etc. Complication risk depends on type and severity of the underlying pathology. Mitral stenosis (MS) is the most common acquired valvular heart disease seen i...
Article
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Copy number variants (CNVs) represent major etiologic factors in rare genetic diseases. Current clinical CNV interpretation workflows require extensive back-and-forth with multiple tools and databases. This increases complexity and time burden, potentially resulting in missed genetic diagnoses. We present the Suite for CNV Interpretation and Priori...
Preprint
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Background: There is scarce information on recent trends in excess deaths and years of potential life lost among Black populations compared with White populations in the United States. Methods: We used death certificates data from the Centers for Disease Control and Prevention WONDER from 1999-2020 and evaluated trends in excess age-adjusted mortal...
Article
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Background and Objective Depression is a common mental health condition that is clinically serious and a cause of public concern. The physiological, psychological, and social changes during adolescence raise the risk of Major Depressive Disorder (MDD) and other depressive disorders. Teenagers' MDD symptoms are similar to those of adults, but they a...
Conference Paper
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More than 3 billion people lack access to safe water for drinking. Availability and access to water services are fundamental in preserving the health and well-being of humans. The quality of water has to be of a certain degree to be considered safe for consumption. Storage vessels tend to develop microbes over time lowering the quality of water. Th...
Article
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The 2021 guidelines of the European Society of Cardiology on the diagnosis and therapy of heart failure (HF) introduced relevant changes in the pharmacological treatment of chronic HF. Among these, certainly the most significant was the introduction in the therapeutic flow-chart (with the highest recommendation level) of the sodium glucose co-trans...
Article
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Sex-based medicine is an important emerging discipline within medicine. We investigated the clinical characteristics, complications, and outcomes of Nonalcoholic Fatty Liver Disease (NAFLD) in females compared to males. Demographics, comorbidities, malignancy, complications, outcomes, and all-cause mortality of NAFLD patients older than 18 years we...
Article
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During 2020 and 2021, Australia implemented relatively stringent government restrictions yet had few COVID-19 deaths. This provides an opportunity to understand the effects of lockdowns and quarantining restrictions on short-term mortality and to help provide evidence in understanding how such public health policies can impact on health. Our analys...
Article
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Some studies have indicated that the use of 2D-Speckle tracking echocardiography (2DSTE) aids in predicting recovery of myocardial contractile function after revascularization in patients with chronic ischemic left ventricular (LV) dysfunction or acute myocardial infarction (MI). The purpose of this meta-analysis was to evaluate the diagnostic accu...
Conference Paper
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One of the main sources of global increase in mortality rate could be linked to heart related diseases according to recent studies. The diagnosis process involved in the analysis of heart diseases data is cumbersome; hence the need for a data mining tool to ease the process. This paper, therefore, aims to investigate and compare the accuracy of dif...
Article
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Background: Hypokinetic non-dilated cardiomyopathy [HNDC/DCM (ND-H)] is a recently proposed (by ESC, 2016) subtype of dilated cardiomyopathy (DCM), which is characterized by the absence of left ventricular (LV) dilatation despite of global LV systolic dysfunction. Knowledge regarding clinical severity and outcomes of patients with DCM (ND-H) is ver...
Article
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Over the past several years, I have been interacting with an increasing number of Iranian scientists, including those currently living in Iran as well as others who are being educated elsewhere or have independent positions outside of that country. In all circumstances, the resulting collaborations have extended my own knowledge and allowed me to c...
Chapter
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The main characteristics of three approaches to cardiac care using public data networks are presented. All efforts were addressed to get minimum-cost solutions for low-budget public health systems. The first solution was developed to follow-up arrhythmic patients between medical consultations, setting a more closed patient-physician relationship, a...
Article
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The objective of this study was to investigate the effect of age and BMI on the risk of death in patients with coronavirus disease 2019 (COVID-19). A cohort of 206 Saudi COVID-19 patients was included in this study. Data on age, BMI, hospitalization, comorbidities, and death were collected and analyzed. Descriptive, univariate, and multivariate log...
Article
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Myocardial infarction is a type of heart disease marked by rapid progression and high mortality. In this paper, a novel intelligent recognition algorithm of multiple myocardial infarctions using a bidirectional long short-term memory (BiLSTM) neural network classification was proposed. This algorithm was based on morphological feature extraction, w...