HIV - Science topic
- Would the approach of incubating HIV particles with either a) WT CD4 memory cells or b) PD-1 negative CD4 memory cells be sufficient? I understand that I would have to define which subset I was focusing on, given the heterogeneity of these cells.
- What is the appropriate source of memory cells? i.e, extracting memory cells from a human and then deleting PD-1 vs. using some sort of CD4 memory cell line.
- Is proviral integration a sufficient marker of latency?