Growth Factors - Science topic

Introduction: This work start observing the efficacy of the KEGEL exercise for pelvic floor rehabilitation in BHP (and overactive bladder) and the effect played by 5 alfa reduttase inibitors and by Urtica dioica in this condition. The increase of the efficiency of the external uretral sfincthere help in controlling urge minction.

Introduction: This work start observing the efficacy of the KEGEL exercise for pelvic floor rehabilitation in BHP (and overactive bladder) and the effect played by 5 alfa reduttase inibitors and by Urtica dioica in this condition. The increase of the efficiency of the external uretral sfincthere help in controlling urge minction.

Metabolic shifts are a hallmark of numerous biological processes, including the differentiation of stem cells along a specific lineage and the activation of diverse cell types, such as immune cells. This review examines the intricate energy metabolic alterations that occur in diverse biological settings, from embryonic development to adult tissue h...

Transportation problems such as congestion, air pollution, accidents, queues, and delays can be encountered with low or large quantity levels. This problem is often encountered in several cities in Indonesia, including in Sukabumi. The growth in the volume of road traffic, especially in Sukabumi City, continues to increase rapidly due to the growth...

Convolvulus arvensis L., has both competitive and invasive properties that can directly or indirectly damage the other plants by production of carbon-based chemicals known as allelochemicals. The goal of the current investigation is to find the allelopathic capability of Convolvulus arvensis L. against Zea mays L. Leaves of Convolvulus arvensis L.,...

Embryonic hematopoietic cells develop in the fetal liver (FL), surrounded by diverse non-hematopoietic stromal cells. However, the spatial organization and cytokine production patterns of the stroma during FL development remain poorly understood. Here, we characterized and mapped the hematopoietic and stromal cell populations at early (E12.5–14.5)...

Surface tension is critically important in the hygroscopicity prediction of nano-aerosols, but experimental measurements of suspended nanodroplet surface tension are currently unattainable. In this study, effect of size and solute concentration on the surface tension of aqueous ammonium sulfate (AS) droplet smaller than 10 nm is investigated based...

Hydro-priming is a seed pre-treatment technique, explored as a potential factor influencing the early seedling development of different maize cultivars. This study investigates germination rates, seedling vigor, and other growth factors in a planned way to help researchers identify the best hydro-priming times for different types of maize. This wil...

Purpose: This study aims to identify rice farmers' motivation levels and evaluate the relationship between needs categories based on the ERG Theory (existence, relatedness, growth) and rice farming in Rangdumulya Village, Pedes District, Karawang Regency. Methodology: A mixed-method approach was employed, combining quantitative and qualitative meth...

In 2023, a workshop was organized by the UK charity Cure Parkinson's with The Michael J Fox Foundation for Parkinson's Research and Parkinson's UK to review the field of growth factors (GFs) for Parkinson's disease (PD). This was a follow up to a previous meeting held in 2019. ¹ This 2023 workshop reviewed new relevant data that has emerged in the...

The relationship between financial development and economic growth were the subject of many recent theoretical and empirical works. These works generally focused on link between finance and growth according to the maturity of financial systems. The Tunisian economy knew a long period of financial repression before starting several phases of liberal...

Economic growth factors in different countries have their own special resources and features due to the difference in development process and environment structure. The authors analyzed the influence of the science parks upon the economic indicators on the example of Russia. Although there are organizations in Russia created to support the science...

Since its introduction in 2001, multiple platelet-rich fibrin (PRF) centrifugation protocols have emerged, but the variations in growth factor release that result from these protocols remain unclear. This review aimed to evaluate growth factor release across three PRF protocols: leukocyte-PRF (L-PRF), advanced-PRF (A-PRF/+), and injectable-PRF (i-P...

Today, the modernization of the production structure – with the outline of high-tech industries, spheres ofscience and education as key growth factors – is one of the main conditions of sustainable development of everycountry, as well as of growth of public prosperity. However, to reach economic stability requires thedevelopment of the system resea...

The economic development is ensured by the capability of a socioeconomic system to have a stable and extended reproduction connected with investment security and its effective use. An investment scale and efficiency influence the replacement and extended reproduction of fixed capital and the society’s social development. The paper aims at analyzing...

Pendahuluan: Permasalahan terkait Human Immunodeficiency Virus (HIV) telah menjadi perhatian global sebagai penyakit menular yang menginfeksi 36,9 juta pasien pada tahun 2015. Nyeri neuropatik merupakan salah satu komplikasi neurologis yang sering terjadi pada pasien dengan infeksi HIV. Brain- Derived Neurotrophic Factor (BDNF), faktor pertumbuhan...

Platelet-rich-plasma (PRP) is a concentrate of plasma containing high levels of platelets and different growth factors, involved in various cellular and regenerative processes, i.a. wound healing and tissue regeneration. Currently, due to its regenerative properties, PRP is widely used in different medical conditions. This paper summarizes knowledg...

BACKGROUND: Severe or recurring major depression is associated with increased adverse childhood experiences (ACEs), heightened atherogenicity, and immune-linked neurotoxicity (INT). Nevertheless, the interconnections among these variables in outpatient major depression (OMDD) have yet to be determined. We aim to determine the correlations among INT...

En varios países latinoamericanos, la minería se ha ido consolidando como uno de los sectores más importantes, tanto como factor de crecimiento económico, como componente vital de las exportaciones. Esto ocurre en una región que ha basado su oferta exportadora en bienes que en general, tienen poco valor agregado.

Cultivated meat production offers solutions in addressing global food security and sustainability challenges. However, serum-free media (SFM) used in cultivating the cells are expensive, contributing to at least 50% of variable operating costs. This review explores technologies for cost-effective SFM, focusing on reducing cost from using growth fac...

Zusammenfassung Die extrakorporale Stoßwellentherapie (ESWT) kann die Heilung insbesondere am Knochen – aber nicht nur dort – beschleunigen. Die akustischen Wellen werden über Mechanotransduktion in eine Gewebeantwort übersetzt. Neben der Stammzellaktivierung werden auch Effekte auf die Exosomenausschüttung, die Modulation der Inflammation und Wach...

Chemical reaction networks (CRNs) are essential for modeling and analyzing complex systems across fields, from biochemistry to economics. Autocatalytic reaction network -- networks where certain species catalyze their own production -- are particularly significant for understanding self-replication dynamics in biological systems and serve as founda...

O Enxerto de Tecido Conjuntivo Subepitelial (ETCS) é o procedimento com maior previsibilidade de cobertura radicular completa, porém, está associado à dor e desconforto, uma vez que, na maior parte dos casos o leito doador é o palato. Visando a regeneração de tecidos e a cicatrização de feridas, a laserterapia de baixa potência e as preparações de...

Owing to their high drug loading capacity, high surface area to volume ratio and small size electrospun nanofibres have garnered significant interest in the delivery of drugs. Electrospinning techniques including mix or blend, coaxial, emulsion and melt electrospinning techniques have been utilized to create electrospun nanofibres for use in biomed...

Background Healing complications are a significant concern after hypospadias repair, often attributed to deficient growth factors and reduced healing potential of hypospadiac tissue. Platelet-Rich Fibrin (PRF), a new generation of platelet concentrates rich in growth factors, has been successfully applied to provide a mechanical barrier and promote...

Recently, there has been a significant increase in the use of artificial intelligence in healthcare, an increased trust of healthcare providers in artificial intelligence, and the interest of investors in the development of healthcare solutions based on artificial intelligence. The vast majority of providers of medical services and technologies, as...

Disruption of HIV-1 Integrase (IN) interactions with the host-factor Lens Epithelium-Derived Growth Factor (LEDGF)/p75 leads to decreased, random integration, increased latent infection, and described here, accumulation of HIV-1 antisense RNA (asRNA). asRNA increase was observed following interruptions of IN-LEDGF/p75 interactions either through ph...

Context. Constituting a relatively small fraction of the extended-jetted population, giant radio galaxies (GRGs) form in a wide range of jet and environment configurations. This observed diversity complicates the identification of the growth factors that facilitate their attainment of megaparsec scales. Aims. This study aims to numerically investig...

Previous studies have explored nanofat stimulating tissue regeneration and maturation, promoting remodeling through its rich content of growth factors and stem cells; however, comprehensive data on its use in full-thickness wounds remains limited. The aim of this study was to evaluate the effectiveness of combining nanofat with freeze-dried human a...

Las mutaciones tratables en el gen del receptor del factor de crecimiento epidérmico (EGFR) son comunes en el cáncer de pulmón no microcítico (CPNM). La terapia dirigida con inhibidores de la tirosina quinasa (ITK) ha transformado los resultados, pero la resistencia plantea desafíos. El perfil molecular es crucial para el tratamiento personalizado....

The study aims to examine the time-varying causality between political stability and economic growth. Secondly, study also evaluates the effect of political stability on economic growth of the United Kingdom and the United States. Therefore, a time-series model is proposed to assess the framework’s constancy with time, which assumes that the coeffi...

Hypertensive disease of pregnancy (HDP) is one of the most important causes of increased maternal mortality and perinatal complications during pregnancy. We investigated the pregnancy outcomes of 156 HDP patients (65 gestational hypertension [GH], 13 chronic hypertension [CH], 74 preeclampsia‐eclampsia [PE‐EC], and 4 superimposed on PE [CH with PE]...

Based on the comprehensive analysis of the current status of the macroeconomy, economic growth factors, and policy impacts, the United States economic growth faces numerous uncertainties. It is imperative to closely monitor various aspects of the situation to gain a more accurate understanding and better predict the future economic trend. The compl...

In contrast to the extensive evidence from animal studies, only few human data are available on the relation of vascular growth factors and collateral function as well as on the conditions which may modify their release or function. In 31 patients with total coronary occlusion (TCOs) blood was collected from distal to the occlusion site (collateral...

Resumo Introdução: O objetivo deste estudo foi investigar o papel do fenofibrato, um agonista do receptor ativado por proliferadores de peroxissoma-α, na lesão renal induzida por obesidade (lipotoxicidade) em camundongos submetidos à uninefrectomia. Métodos: Camundongos C57BL/6 foram submetidos a uninefrectomia e cirurgias simuladas (sham) e alimen...

The countriesof Central and Southeastern Europe (CSEE)aresignificant net recipientsof remittances, primarily due to the intensive emigration trends that occurred after they transitionedto market economies.The fact that these countries are among the highest recipients of private remittances in Europe,suggeststhatsuch financial inflows could potentia...

Introdução No momento do registro de um medicamento no Brasil, os dados usados para aprovação são baseados em estudos com uma população específica, o que limita o número de pessoas que poderiam usar o medicamento. No entanto, é comum a expansão da indicação para outras condições clínicas com o passar do tempo. Considerando que os preços de novos me...

Introdução O carcinoma (ca) de mama é a neoplasia maligna mais incidente em mulheres na maior parte do mundo. O objetivo é descrever o histórico das Diretrizes Diagnósticas e Terapêuticas (DDT) do ca de mama no Brasil que foram analisadas pela Comissão Nacional de Incorporação de Tecnologias no Sistema Único de Saúde - CONITEC Esta Comissão foi cri...

The interplay between nutritional status, body mass index (BMI), and growth factors, notably insulin-like growth factor-1 (IGF-1), is intricate yet essential for deciphering growth dynamics in children. Our study probes these interactions to pinpoint potential avenues for enhancing pediatric growth outcomes.

This study analyzes the effects of governance on the relationship between research and development expenditure and economic growth in South Africa using annual data from 1997 to 2022 using an autoregressive distributed lag (ARDL) model. The calculated F-tests for the two models in the ARDL bounds testing approach to cointegration revealed a long-ru...

Objetivo: Comunicar los resultados del tratamiento de la úlcera de pie diabético con rhFCE en 5 pacientes asistidos en la Unidad de Pie del Hospital Público. Material y método: Estudio observacional, descriptivo y retrospectivo de los registros ambulatorios de pacientes diabéticos mayores de 18 años, con úlceras neuroisquémicas de al menos 4 seman...

The worldwide organ scarcity dilemma is being made worse by some of the recent advances in 3D bioprinting, which offer revolutionary opportunities for the repair of organs and tissues. The method enables the accurate manufacturing of biological tissues by stacking bioinks including cells, biomaterials, and growth factors. Unlike traditional organ t...

La gonartrosis es una condición degenerativa que afecta a una proporción significativa de la población, particularmente a personas mayores o con antecedentes de lesiones articulares. Se caracteriza por dolor, rigidez de la articulación y disminución de la funcionalidad con un evidente deterioro severo de la calidad de vida del paciente y convirtien...

O Carcinoma Basocelular (CBC) é o tipo de câncer de pele mais comum, originado a partir de células basais epiteliais que perdem suas funções normais de diferenciação e queratinização. Este estudo explorou a relação entre Variantes de Polimorfismo de Nucleotídeo Único (SNPs), especificamente rs121434569 e rs121434568, no gene do Receptor do Fator de...

This work analytically compares the growth of Backward Stimulated Raman Scattering (B-SRS) induced by temporal laser pulses on the order of a few tens of laser cycles or a couple of picoseconds for nominally 10 um wavelength IR pulse with Gaussian versus the constant intensity profile assumed in the original theory, both delivering an equivalent en...

The learning approach of undergraduate medical students can be influenced by motivations toward learning medicine as well as perceived outcomes such as their specialty preference in the future. In this study, we analyze the relationships between learning approach, motivation to study medicine, and factors related to their specialty preference. We c...

Giant radio galaxies (GRGs), a minority among the extended-jetted population, form in a wide range of jet and environmental configurations, complicating the identification of the growth factors that facilitate their attainment of megaparsec scales. This study aims to numerically investigate the hypothesized formation mechanisms of GRGs extending $\...

The ability to heal from wounds is perhaps the most important biological function that ensures our survival and perpetuation. Cutaneous wound healing typically consists of four characteristic stages, namely hemostasis, inflammation, proliferation, and remodeling, which are carefully carried out by coordinated actions of various cells, cytokines, an...

There is a significant prevalence of temporomandibular joint (TMJ) disorders, estimated at 34% according to various sources. Given that this condition often leads to a reduced quality of life and disability, there is a pressing need to develop and implement effective treatment methods. Arthrocentesis, along with the injection of pharmacological age...

Adult neural stem and progenitor cells (NSPCs) reside in the dentate gyrus (DG) of the hippocampus throughout the lifespan of most mammalian species. In addition to generating new neurons, NSPCs may alter their niche via secretion of growth factors and cytokines. We recently showed that adult DG NSPCs secrete vascular endothelial growth factor (VEG...

Introdução: A matriz dentinária vem sendo considerada recentemente como alternativa para enxerto, visto que apresenta estrutura semelhante ao osso alveolar. Os enxertos podem ser preparados de forma mineralizada, que foca nos componentes orgânicos e inorgânicos, ou desmineralizada, que expõe a estrutura de colágeno e permite a liberação de fatores...

Atualmente, a valorização da estética tem se intensificado de forma notável. Para muitos, a busca por métodos que garantam a manutenção de uma aparência jovem, a preservação da autoestima e a projeção de uma imagem pessoal positiva tem se tornado uma prática comum, evoluindo rapidamente em diferentes contextos. O envelhecimento da pele é um process...

The effect of ancestral genetic diversity, captured by a novel index, on the levels of three latent variables (Self-efficacy, General Phobia, and General Growth factors) is examined using a large pediatric imaging sample to test for the presence of outbreeding depression (i.e., worse outcomes among individuals in proportion to their degree of ances...

A myriad of growth factors and receptors, whose effects are intertwined in complex interactions, do not only orchestrate tumor angiogenesis [...]

Nozzle shape greatly affects the activity of cells and growth factors inside bio-ink, which is easy to be ignored. In this research, the finite element simulation software based on fluid dynamics theory was used to simulate the extrusion flow behavior of the bio-ink inside the printing needle. By establishing the flow models of two commonly used ne...

Colorectal cancer (CRC) commonly metastasizes to the liver, and this poses a significant clinical challenge. Tumor-associated macrophages (TAMs), key players within the TME, play a significant role in promoting CRC metastasis by secreting various chemokines, growth factors, and cytokines. This review not only aims to enhance our knowledge of TAMs’...

El plasma rico en plaquetas (PRP) es el volumen de plasma autólogo que contieneuna alta concentración de plaquetas más factores de crecimiento y fibrina que ayudan auna rápida cicatrización de las heridas. Se han reportado múltiples casos de su uso endiferentes especies animales, tanto domésticas como silvestres; sin embargo, los proto-colos para s...

Platelets are the first to reach the site of tissue damage and secrete substances like platelet growth factors (GFs), which perform many different functions in the human body. Many studies suggest that GFs such as transforming GF (TGF), platelet-derived GF (PDGF), or insulin-like GF-1 (IGF-1) may be markers of survival, disease severity, and post-c...

Background Livmoniplimab is an IgG4 that targets the glycoprotein-A repetitions predominant-transforming growth factor (GARP-TGF)-β complex, blocking release of active TGF-β1 and facilitating anti-tumor immune response. It is being investigated in combination with budigalimab (anti-PD-1) in patients with solid tumors. To address Project Optimus, we...

This poster is my doctoral thesis which was printed in book form. The title of my thesis is: "Human capital in the system of economic growth factors"

The Author reports the use of Etaluma Immunofluorescence Microscope in the saliva protein analysis of growth factors and cytokines. Most of the identified Human Growth Factors and Cytokines found in plasma and various stem cell therapeutic sources are also found in saliva, making saliva a preferred sample for testing. Being non-invasive, saliva sam...

We present a framework for modeling liver regrowth on the organ scale that is based on three components: (1) a multiscale perfusion model that combines synthetic vascular tree generation with a multi-compartment homogenized flow model, including a homogenization procedure to obtain effective parameters; (2) a poroelastic finite growth model that ac...

In this work, we describe the transcriptional profiles of preadapted and non-adapted one-month-old juvenile Baikal whitefish after heat shock exposure. Preadapted fish were exposed to a repeated thermal rise of 6 °C above the control temperature every three days throughout their embryonic development. One month after hatching, preadapted and non-ad...

A alopecia é uma condição comum que afeta milhões de pessoas, resultando em perda capilarsignificativa e impactos psicológicos. Recentemente, o uso de fatores de crescimento ebiomateriais tem se destacado como uma abordagem inovadora no tratamento regenerativocapilar. Esta revisão integra estudos clínicos e experimentais que investigam a eficácia d...

Introduction: Spontaneous tumor regression is the volumetric reduction or complete disappearance of a primary tumor or metastatic sites (single or multiple) without the administration of treatments. This rare phenomenon occurs most commonly in certain types of neoplasms. Case Presentation: In this manuscript, we describe a spontaneous tumor regress...

Hexagonal TiO2 nanotubes (hTNTs) mimic a honeycomb structure, indicating their high potential as implantable materials due to their superior mechanical, chemical, and biological properties. However, the fabrication of hTNTs with a hexagonal base and six rectangular sides poses significant challenges, underscoring the importance of this research. Th...

This paper analyzes city system dynamics, based on a theoretical framework relating interaction potentials to agglomeration economies and density externalities. It employs new historical time series data on population size of cities in Sweden over two centuries (1810–2010) and introduces two schematic growth factors: (i) the intra-city potential an...