Generalized Anxiety Disorder - Science topic

Introduction Generalized anxiety disorder (GAD) is the most common type of anxiety disorders. GAD usually occurs in adolescence or early adulthood, and the prevalence of GAD is higher among college-enrolled young adults than in the general adult population. However, there is a lack of evidence regarding the effectiveness of acupuncture in the treat...

Nascent public health research has identified linkages between sanitation experiences and mental health. The present study examined associations between sanitation-related empowerment resources (Bodily Integrity, Safety and Security, Privacy, and Time) and mental health outcomes (well-being, depression, and anxiety). We conducted a secondary analys...

Background Though frailty is common in aging, its impact on varied health outcomes has been grossly understudied among rural Indians. We aimed to cross‐sectionally examine the impact of physical frailty on 13 health outcomes and brain structure in this population. Method Participants (n=5302) were non‐demented, aging individuals (=45 years) from t...

Background The phenotype model of frailty, initially proposed by Fried, is primarily confined to the physical dimension. This study seeks to expand this model by integrating the psychological dimension. We hypothesize that this psychological frailty model is strongly associated with cognitive functional impairment (CFI) in an aging Indian populatio...

Background Though frailty is common in aging, its impact on varied health outcomes has been grossly understudied among rural Indians. We aimed to cross‐sectionally examine the impact of physical frailty on 13 health outcomes and brain structure in this population. Method Participants (n=5302) were non‐demented, aging individuals (≥45 years) from t...

Background There are 55 million persons living with dementia (PLwD) today, projected to 139 million by 2050. As they progress towards dementia’s advanced stages, hospice care becomes crucial to manage their symptoms and the caregiver burden. Solo family caregivers, particularly lacking in social support, are vulnerable to deteriorating physical and...

Background Elderly individuals living alone represent a vulnerable group with limited family support, making them more susceptible to mental health issues such as depression and anxiety. This study aims to construct a network model of depression and anxiety symptoms among older adults living alone, exploring the correlations and centrality of diffe...

Rationale Psychedelic-assisted therapy is increasingly applied within mental health treatment. Objectives This study focused on factors moderating changes in the acute and long-term effects of an individual psilocybin-assisted program on depression, anxiety, PTSD and personality structures by including demographic factors, subjective experience an...

Bipolar disorder (BD) frequently coexists with anxiety disorders, creating complex challenges in clinical therapy and management. This study investigates the prevalence, prognostic implications, and treatment strategies for comorbid BD and anxiety disorders. High comorbidity rates, particularly with generalized anxiety disorder, underscore the nece...

In the original publication [...]

Background The high comorbidity and symptom overlap of generalized anxiety disorder (GAD), posttraumatic stress disorder (PTSD), and social anxiety disorder (SAD), has led to the study of their shared and disorder-specific neural substrates. However, the morphometric similarity network (MSN) differences among these disorders remain unknown. Method...

Large language models (LLMs) are increasingly attracting the attention of healthcare professionals for their potential to assist in diagnostic assessments, which could alleviate the strain on the healthcare system caused by a high patient load and a shortage of providers. For LLMs to be effective in supporting diagnostic assessments, it is essentia...

Individuals with general anxiety disorder (GAD) have an impaired future-oriented processing and altered reward perception, which might involve the ventromedial prefrontal cortex (vmPFC) and dorsolateral prefrontal cortex (dlPFC). Twenty-nine adults with GAD performed the balloon analogue risk-taking task (BART) and delay discounting task (DDT) duri...

Worry is the main characteristic of generalized anxiety disorder (GAD), a psychological disorder whose prevalence is high worldwide in adults, adolescents, and children. The Penn State Worry Questionnaire for Children (PSWQ-C) is a widely researched instrument that measures GAD pathological worry. It comprises 14 items, 11 direct and three reverse-...

BACKGROUND: Emotional distress increases, also affected by the setting. OBJECTIVE: To estimate changes in prevalence of severe anxiety and depressive symptoms and associated factors. DESIGN AND SETTING: This cross-sectional study included adults living in Manaus selected through a three-stage probability sampling in 2015 and 2019. METHODS: This is...

Mood and Cognitive Dysregulation Disorder (MCDD) represents a synthesis of overlapping features from multiple neuropsychiatric disorders. This article explores the integrated characteristics, brain regions affected, and the functional impact of MCDD, combining aspects of Bipolar Disorder, Attention-DeficitHyperactivity Disorder (ADHD), Major Depres...

Introduction: Mental health disorder causes significant disturbance to every aspect of an individual’s life. Almost one in every eight people in the world lives with a mental disorder. In this study, we aimed to measure the prevalence and determinants of anxiety and depression among reproductive-aged women in Bangladesh. Methodology: We utilized da...

This study explores the application of the Contrast Avoidance Model (CAM) within virtual reality exposure therapy (VRET) for treating generalized anxiety disorder (GAD). Recognizing GAD's pervasive impact and the limitations of traditional cognitive-behavioral therapy (CBT), this research aims to design, implement, and evaluate CAM-based interventi...

Background Duloxetine, a serotonin and norepinephrine reuptake inhibitor (SNRI), is used to treat various health conditions, including major depressive disorder, generalized anxiety disorder, fibromyalgia, and off‐label for chemotherapy‐induced pain. We conducted this systematic review and meta‐analysis aiming to test the current evidence regarding...

Background Chromosome 3q29 duplication syndrome is a rare chromosomal disorder with a frequency of 1:5000 in patients with a neurodevelopmental phenotype. The syndrome is characterized by phenotypic polymorphism and reduced penetrance. Methods Patients were investigated by performing a cytogenetic analysis of GTG‐banded metaphases, aCGH with the S...

BACKGROUND: Specific components of independent and interdependent self-construal have been associated with psychopathology. However, most studies on this topic have been cross-sectional, precluding causal inferences. We used contemporaneous and temporal cross-lagged network analysis to establish weak causal influences in understanding the associati...

Objective: Postoperative nausea and vomiting (PONV) was one of the common complications in patients with HCC who had undergone TACE. This study was a prospective analysis of patient data to investigate risk factors for PONV in patients after TACE. Material and Methods: Data were collected from 212 patients undergoing TACE in the interventional depa...

AIM: The purpose of this study was to assess cognitive vulnerability and response style in clinical and normal individuals.METHOD: A sample of 90 individuals was selected for each of the 3 groups of Generalized Anxiety disorder, Dysthymic disorder and normal individuals. They completed MCQ and RSQ.RESULTS: Results analyzed by MANOVA and post hoc sh...

Background: To study the degree of compliance of primary care neuropsychiatric drug dispensing companies in following the pricing norms set by the Drug Price Control Order (DPCO). Methods: This is an observational analytical study where the drug strength and ceiling price of the generic primary care mental disorder drugs were obtained from the Nati...

Este artículo, denominado "Estrategias de intervención cognitivo-conductual en el manejo de la ansiedad generalizada": "Eficacia y perspectivas futuras" explora la eficacia de las intervenciones fundamentadas en la terapia cognitivo-conductual (TCC) en el manejo del trastorno de ansiedad generalizada (TAG) Este trastorno, definido por una preocupac...

BACKGROUND: Anxiety disorders among medical students constitute a global problem, and also reflect the mental state of the general population. There is paucity of data on the spectrum of such disorders among medical students in Nigeria.AIM: The study aims to determine the prevalence of anxiety disorders among medical students, and the effect of soc...

OBJECTIVE: To identify the relationship between anxiety and depression with the severity of fibromyalgia and quality of life in patients aged 18 to 65 years, clinic of rheumatology of Barranquilla. METHODS: Observational, descriptive, comparative cross-sectional study. Patients with fibromyalgia who attend the external consultation of rheumatology...

Background The present study aimed to investigate the effect of acupuncture on generalized anxiety disorder (GAD) in healthcare students. On the basis of increasing prevalence of anxiety disorders in this population and the research gap regarding the use of acupuncture as a therapeutic intervention, this study aims to fill this gap and provide soli...

Generalized Anxiety Disorder is categorized as psychiatry neurosis. Until today, there are no dominant factors that have been identified in influencing this disease to occur among university students. Problems in education, family, social and many others are some of the issues which result continous anxiety to these university students. This also g...

BACKGROUND: Depression and anxiety are common prevalent in patients with chronic disease, and Chronic illness are long-lasting conditions with persistent effects and complications. Depression and anxiety disorders are well known to have a negative but significant impact on the course, outcomes, long-term survival, and treatment efficacy of patients...

BACKGROUND: Depression is one of the most common mental disorders and is associated with a significant increase in the risk of mental and somatic comorbidities. The chronobiological theory of the pathogenesis of depression explains the relationship between the symptoms of depression and disturbance of circadian rhythm regulation. Disrupted circadia...

Background Corona virus disease 2019 (COVID-19) reinfection, particularly short-term reinfection, poses challenges to the management of rheumatic diseases and may increase adverse clinical outcomes. This study aims to develop machine learning models to predict and identify the risk of short-term COVID-19 reinfection in patients with rheumatic disea...

Introduction Anxiety disorders are among the most common mental illnesses in the US. An estimated 31.1% of U.S. adults experience any anxiety disorder at some time in their lives. Understanding some of the molecular underpinnings of anxiety could lead to improved treatments over current strategies focusing on symptom relief rather than root causes....

With its proven track record of success, Imagery Rescripting and Reprocessing Therapy (IRRT) represents a valuable and accessible tool for promoting mental health and well-being among young people. Yet, the impact of this treatment on cognitive fusion and cognitive avoidance in individuals with generalized anxiety disorder (GAD) remains unexplored....

The Generalized Anxiety Disorder (GAD) is one of the most chronic and detrimental disorders and it is considered a common disorder in childhood and adolescence. Furthermore, this disorder is associated with many problems in the health domain. As such, this study attempted to gauge the impact of mindfulness-based stress reduction on intolerance of u...

Aim of the Study: General procrastination and Generalized Anxiety Disorder (GAD) are two influential variables that might impact significantly on the lives of students. However, probable interventions and non-pharmaceutical treatments are yet to be discovered that might break the association between general procrastination and GAD. Methodology: To...

United States institutions of higher education (IHEs) transitioned to online learning in response to the COVID-19 pandemic, and guidelines to reduce risk of spreading or contracting the disease. This large scale, impromptu transition to online learning had implications for students, and IHEs. This study used a survey design to explore the impact of...

Excessive screen time was associated with mental health problems, yet whether the associations differ by screen content types remain unknown. Here, we conducted a cross-sectional study of adolescents from 156 junior and high school to investigate the association of types of on-screen content with mental health problems in China. The exposure variab...

Background Universities worldwide are witnessing a surge in mental health problems among students, particularly in anxiety and depression. The Hopkins Symptom Checklist (HSCL) is a popular screening tool, but its reliability in identifying mental disorders remains debated. The aim of this study was to evaluate the criterion validity of the HSCL-25,...

Generalized Anxiety disorder is one of the most common psychiatric disorders, which involves persistent anxiety lasting for several months, characterized by general apprehension or excessive worry about everyday issues like family, health, or work. A 24-year-old male, who came with the complaints of, reduced concentration in studies, reduced self-c...

Introducción: Este estudio examina la relación entre el maltrato infantil y los trastornos psicológicos, específicamente la depresión y la ansiedad, en una muestra de 200 niños y adolescentes derivados a la Unidad de Atención Especializada en Psicología por maltrato físico, psicológico o negligencia. Metodología: Utilizando un diseño no experimenta...

Objective This study investigates persistent physical and neuropsychiatric symptoms in Long COVID, focusing on their severity and assessing risk/resilience factors, including conscientiousness and neuroticism. The study utilizes a mediation model to explore the potential role of psychological distress in mediating its impact on cognitive decline....

Background Mental health conditions among academic staff are a growing global concern, driven by factors such as heavy workloads, job insecurity, and a lack of institutional support. Anxiety, one of the most common mental health problems, is particularly widespread in academia, affecting cognitive function and productivity. In Ukraine, the ongoing...

Background Individuals exposed to wildfires are at risk of developing adverse mental health conditions in the months following the event. Receiving supportive text interventions during and after a wildfire event can have a significant impact on reducing mental health conditions over time. Objectives The study aimed to assess the effectiveness of a...

Introduction. Due to limited information on mental health in rural areas, this study innovates by applying validated tools previously unused in rural Honduras to assess levels of anxiety and depression among rural residents of Ojojona, Honduras. Methods. The Patient Health Questionnaire-9 (PHQ-9) and the Generalized Anxiety Disorder Scale-7 (GAD-7)...

Cynicism has been associated with adverse mental and physical health outcomes. This study investigated the role of cynicism in relation to indices of mental health among South African first responders. Research has highlighted that first responders are at increased risk of adverse mental health outcomes owing to the nature of their work. The sample...

Background and objectives Natural disasters are harmful occurrences caused by the Earth's geological and meteorological processes. Bangladesh is recognized as one of the country's most vulnerable to natural disasters. Therefore, the people of Bangladesh remain at high risk of natural disasters. However, no study has been conducted in Bangladesh to...

Background England's primary care service for psychological therapy (Improving Access to Psychological Therapies [IAPT]) treats anxiety and depression, with a target recovery rate of 50%. Identifying the characteristics of patients who achieve recovery may assist in optimizing future treatment. This naturalistic cohort study investigated pre-therap...

Lysergic acid diethylamide (LSD) is a classic serotonergic psychedelic that induces a profoundly altered conscious state. In conjunction with psychological support, it is currently being explored as a treatment for generalized anxiety disorder and depression. The dorsolateral prefrontal cortex (DLPFC) is a brain region that is known to be involved...

Background: Medical students frequently experience heightened levels of anxiety, depression, and burnout. These challenges are disproportionately borne by students from underrepresented backgrounds, who are exposed to systemic inequities, discrimination, and reduced access to supportive resources. While precision wellbeing approaches, characterized...

Depressive and anxiety symptoms are more prevalent in patients with cirrhosis compared to the general population. Between 2009 and 2019, the prevalence of depression in cirrhosis increased by 80%, while the prevalence of generalized anxiety disorder increased by over 400%. When present, anxiety and depression are linked to lower health-related qual...

This study aims to explore the relationship between social media use and Generalized Anxiety Disorder (GAD) among students. A sample of 76 participants aged 18 to 25 was assessed using two standardized tools: the Hamilton Anxiety Scale, which measures the severity of anxiety, and the Social Media Addiction Scale (SMAS), designed to quantify the ext...

Background: The gut–brain axis, significantly influenced by the gut microbiome, is a growing focus in mental health research. This study aimed to investigate gut microbiome differences between anxious and non-anxious participants. Methods: A convenience sample of 119 participants consisted of 56 participants with self-assessed low to zero levels of...

Objective As the Internet has undergone a significant increase, the smartphone has become the primary electronic device used for accessing it. However, several adverse effects on health and also psychological disorders, such as the fear of not being able to use a mobile phone and/or its services, called nomophobia, may be related to their use. This...

Mental health occasions in staff and faculty members of higher education have vast-ranging effects, narrowing or outstretching opportunities for future beneficial lives and available evidence acquire unprecedented notability. While there has distinguished an upsurge of enthusiasm in utilizing games for learning and teaching, Gamification to optimiz...

Mental health occasions in staff and faculty members of higher education have vast-ranging effects, narrowing or outstretching opportunities for future beneficial lives and available evidence acquire unprecedented notability. While there has distinguished an upsurge of enthusiasm in utilizing games for learning and teaching, Gamification to optimiz...

Introdução: Há milhões de microrganismos convivendo no intestino humano, e esse sistema é chamado de microbiota gastrointestinal. Suas funções são: digestão e absorção de nutrientes; regulação imunológica; proteção contra patógenos; integridade da barreira intestinal. Objetivo: Compreender como a comunidade microbiana intestinal pode impactar o est...

Purpose The study presents a cross-sectional analysis of the population of Ukrainian women who received maternity care in 11 Polish hospitals. Methods Multidirectional lactation counseling was implemented from March to November 2023 by the Human Milk Bank Foundation in cooperation with UNICEF Refugee Response Office in Poland. Medical data were co...

Background and Objective: Prevalence of psychiatric disorders is increasing radically in Bangladesh. Anxiety disorders are the second most common disorders for both adult and child in Bangladesh. Migrating to other countries are also very common in Bangladesh but there is very limited data about the anxiety level of family members of these expatria...

Corona Virus Disease of 2019 (COVID-19) is an unprecedented challenge to health care systems globally and locally. The study aimed to assess generalized anxiety disorder and associated factors among health care providers (HCP) during COVID–19 pandemic. A total of 202 health care providers participated in the study. This was a hospital-based cross-s...

OBJECTIVE: Chatbots’ rapid advancements raise the possibility that they can be used to deliver mental health support. However, public utilization of and opinions toward chatbots for mental health support are poorly understood. METHODS: Survey study of 428 U.S. university students who participated in early 2024, just over one year after the release...

Background and aims The authors of the present study wanted to know whether the previously reported psychiatric comorbidities of internet gaming disorder (IGD) based on DSM-5 criteria were also more prevalent among gaming disorder (GD) or hazardous gaming (HG) based on ICD-11 criteria. Therefore, the present case-control study evaluated the psychia...

Background University life is a phase of developing personal and professional skills, but it brings challenges such as distancing from family and supporting networks, difficulties with academic tasks, loneliness, new relationships, competitiveness, and social, socioeconomic, and psychological vulnerability, among others. These conditions can lead t...

Background: Parkinson’s disease is a neurodegenerative disorder that occurs due to the damage of the neurons that secrete the neurotransmitter called dopamine and the cases are growing worldwide. The studies on the observation of the non-motor symptoms in patients with Parkinson’s disease are sparse in the Indian context. The estimated prevalence o...

Background When utilized as an adjunct with antidepressants, antipsychotics, and other psychopharmacological drugs, certain amino acids, such as L-Theanine (LT), have shown potential effectiveness in enhancing the symptomatic outcomes of patients with mental disorders. Despite this, there is a lack of previous systematic reviews examining these ass...

Aims The enduring impact of the COVID-19 pandemic on mental health and its implications for COVID-19 vaccine uptake necessitate comprehensive investigation. We aimed to characterize the persistence of moderate to severe anxiety and depression symptoms from July 2020 to July 2023, explore demographic associations with symptom persistence, and assess...

This review summarizes the current meta-analysis literature on treatment outcomes of CBT for a wide range of psychiatric disorders. A search of the literature resulted in a total of 16 methodologically rigorous meta-analyses. Our review focuses on effect sizes that contrast outcomes for CBT with outcomes for various control groups for each disorder...