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Gastroenterology - Science topic

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Publications related to Gastroenterology (10,000)
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In the January 2021 issue of BMC Gastroenterology, Elmokadem et al. report their findings on the use of gastric ultrasound (GUS) for the evaluation of feeding intolerance—defined as high gastric residual volume—in critically ill patients. We voice in this correspondence our concerns regarding certain methodological flaws and believe the study resul...
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Background Germline CDKN2A mutations are a well-known cause of familial atypical multiple mole melanoma (OMIM #155601) and melanoma-pancreatic cancer syndrome (OMIM #606719). Increased risk of head and neck squamous cell carcinoma (HNSCC), particularly oral squamous cell carcinoma (OSCC) in those with germline CDKN2A mutations, has been described....
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Background Chylous ascites (CA) is a rare complication of gastrectomy for gastric cancer. While most cases of postoperative CA improve with medication or nutritional support, some are refractory to conservative treatment. A peritoneovenous shunt (PVS) may help patients who are poor candidates for surgery. However, PVS placement for postoperative CA...
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Background Laryngopharyngeal reflux (LPR) is caused by the regurgitation of gastric contents above the upper esophageal sphincter. Diagnostic gold standard tests like multichannel intraluminal impedance (MII) and 24-h dual-probe pH-metry are invasive and expensive which limits their accessibility especially in resource-limited settings. Since pepsi...
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Immune checkpoint inhibitors (ICI) are treatments for several cancer types. Pathogenesis of ICI-induced colitis is not yet clearly explained as it can be disguised as another form such as inflammatory bowel disease or IBD. Recent studies revealed that ICI-induced colitis is a unique form of colitis wherein the synergy of regulatory T cells with the...
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Nutrition in the first 1000 days of life is essential to ensure appropriate growth rates, prevent adverse short-and long-term outcomes, and allow physiologic neurocognitive development. Appropriate management of early nutritional needs is particularly crucial for preterm infants. Although the impact of early nutrition on health outcomes in preterm...
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Background The introduction of new technologies in endoscopy has been met with uncertainty, skepticism, and lack of standardization or training parameters, particularly when disruptive devices or techniques are involved. The widespread availability of a novel endoscopic suturing device (OverStitch™) for tissue apposition has enabled the development...
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Introduction: Early diagnosis of cancers in the laryngeal and pharyngeal (LF) region is important for minimally invasive treatment and prolongation of survival. In the practice of otolaryngology diseases, hypopha-ryngeal cancers are mostly diagnosed in the late period. The aim of this study is to evaluate the approaches of gastroenterology and gene...
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Background Publications are an important component of academic careers.AimsWe investigated the financial costs to authors for submitting and publishing manuscripts in gastroenterology (GI) journals in the United States (US), United Kingdom (UK), and elsewhere.Methods This was a cross-sectional study carried out from 11/1/2020 to 12/31/2020. We used...
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Background: We aimed to evaluate the diagnostic roles of AFAP1-AS1 and ASB16-AS1 in colorectal cancer and highlight their roles in predicting colorectal cancer patients' prognosis. Methods: In this case-control study, 146 participants were involved. Group I included 47 patients with CRC. Group II composed of 49 patients with benign lesions in th...
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Miaomiao Li,1,* Yue Yuan,1,* Xue Han,2 Xinjuan Liu,1 Weizhen Zhang,2 Jianyu Hao1 1Department of Gastroenterology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Physiology and Pathophysiology, Peking University Health Science Center, Beijing, People’s Republic of China*These authors contr...
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Shanshan Zhang, Jun Zhang, Yifang Li, Jian Jiao Department of Gastroenterology & Hepatology, China-Japan Union Hospital, Jilin University, Changchun, People’s Republic of ChinaCorrespondence: Jian Jiao, Email jjian@jlu.edu.cnIntroduction: IgG4-related disease (IgG4-RD) mimics a variety of disorders, the final diagnosis is heavily dependent on the d...
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Background Endoscopic retrograde cholangiopancreatography (ERCP) is a common, but technically challenging procedure used in the management of hepatopancreaticobiliary (HPB) disease. It is traditionally performed by medical gastroenterologists. In 2014, the British Society of Gastroenterology (BSG) proposed key performance indicators to evaluate and...
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Changjuan Li,1,2 Min Wang,3 Junwei Wei,2 Wenjuan Zhang,2 Haitao Liu,2 Dongqiang Zhao1 1Department of Gastroenterology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, People’s Republic of China; 2Department of Gastroenterology, The First Hospital of Handan City, Handan, Hebei Province, People’s Republic of China; 3Dep...
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Introduction Multiple studies have indicated physicians are practicing medicine in increasingly larger groups. However, specialty-specific data on the extent of consolidation are lacking for many specialties, including gastroenterology. We aim to determine the extent of consolidation for gastroenterology in recent years. Methods The Physician Comp...
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Objective: To find out the frequency of hiatal hernia among patients with dyspepsia undergoing esophagogastroscopy. Study Design: Descriptive, Cross-sectional study. Setting: Departments of Medicine and Gastroenterology, Services Hospital Lahore. Period: December 2018 to June 2019. Material & Methods: A total of 195 patients with dyspepsia aged 20...
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Objective. Based on the nursing analysis of children aged 0∼3 in the Department of Gastroenterology, from the perspective of nursing methods and nutrition, bird’s nest nursing and high-quality nursing methods were used to intervene children to help them improve their gastrointestinal conditions and sleep quality (Su-Jin, 2021). Methods. A total of...
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Background There is significant variability in the performance and outcomes of invasive medical procedures such as percutaneous coronary intervention, endoscopy, and bronchoscopy. Peer evaluation is a common mechanism for assessment of clinician performance and care quality, and may be ideally suited for the evaluation of medical procedures. We the...
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We present a case of a previously asymptomatic 21-year-old female presenting with intestinal perforation secondary to Crohn’s disease for the first time. The patient presented with crampy abdominal pain and frequent bilious vomiting of 3 days duration. She also had a high-grade fever and abdominal distension. WBC was 24,000 and an abdominal CT scan...
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Background: Excessive caloric intake and reduced energy expenditure are associated with the onset of metabolic-associated fatty liver disease (MAFLD). The aim of this study was to probe the benefits of a low glycemic index Mediterranean diet (LGIMD) and a combined exercise program (CEP) on MAFLD by monitoring the clinical process through anthropom...
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In recent decades, tremendous progress has been made in the medicinal field in understanding the molecular mechanisms underlying human pathologies, due to the significant development of advanced laboratory techniques and technologies [...]
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Background and Aims Gastrointestinal (GI) endoscopy is a limited health resource because of a scarcity of qualified personnel and limited availability of equipment. Non-adherence to endoscopy appointments therefore wastes healthcare resources and may compromise the early detection and treatment of GI diseases. We aimed to identify factors affecting...
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Refeeding syndrome refers to a clinical condition whereby biochemical abnormalities such as hypokalemia, hypomagnesemia, and mainly hypophosphatemia occur upon recommencement of feeding, typically in malnourished catabolic patients. A 36-year-old female presented at 30 weeks gestation with hyperemesis gravidarum. During this admission, the patient...
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Background Area postrema syndrome (APS) as the isolated manifestation in autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy has been rarely reported. Case presentation A 61-year-old male patient presented with intractable hiccup. He was first admitted to the department of Gastroenterology because he had no symptoms other than hiccup....
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Objectives: (1) to determine the adherence and persistence rates of adalimumab therapy among Swedish patients with Crohn's disease (CD), and (2) to compare self-administration devices to predict the medication adherence and persistence. Methods: We conducted a retrospective analysis of the Swedish National Board of Health and Welfare database du...
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Background/objectives Reports about the implementation of recommendations from acute pancreatitis guidelines are scant. This study aimed to evaluate, on a patient-data basis, the contemporary practice patterns of management of biliary acute pancreatitis and to compare these practices with the recommendations by the most updated guidelines. Methods...
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Intrahepatic neutrophil infiltration has been implicated in severe alcoholic hepatitis (SAH) pathogenesis; however, the mechanism underlying neutrophil-induced injury in SAH remains obscure. This translational study aims to describe the patterns of intrahepatic neutrophil infiltration and its involvement in SAH pathogenesis. Immunohistochemistry an...
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Colorectal cancer (CRC) continues to be one of the main causes of death from cancer because patients progress unfavorably due to resistance to current therapies. Dysregulation of the Wnt/β-catenin pathway plays a fundamental role in the genesis and progression of several types of cancer, including CRC. In many subtypes of CRC, hyperactivation of th...
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Faecal immunochemical testing (FIT) has a high sensitivity for the detection of colorectal cancer (CRC). In a symptomatic population FIT may identify those patients who require colorectal investigation with the highest priority. FIT offers considerable advantages over the use of symptoms alone, as an objective measure of risk with a vastly superior...
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Retinal drusen are deposits of inflammatory proteins that are found in macular degeneration and glomerulonephritis and result, in part, from complement activation. This was a cross-sectional observational study of individuals with inflammatory bowel disease (IBD) recruited from a Gastroenterology clinic who underwent non-mydriatic retinal photograp...
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Climate change and the destruction of ecosystems by human activities are among the greatest challenges of the 21st century and require urgent action. Health care activities significantly contribute to the emission of greenhouse gases and waste production, with gastrointestinal (GI) endoscopy being one of the largest contributors. This Position Stat...
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Aim. To study the dynamics and pattern of publications in Russian on post-COVID-19 syndrome (PCS) in order to assess the completeness of information and identify medical specialties with its most active investigation in Russia. Material and methods . The search for publications was carried out in the database of the largest digital scientific libra...
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Functional dyspepsia (FD) is a common disorder of gut–brain interaction, affecting approximately 7% of individuals in the community, with most patients managed in primary care. The last British Society of Gastroenterology (BSG) guideline for the management of dyspepsia was published in 1996. In the interim, substantial advances have been made in un...
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Endoscopic ultrasound (EUS) gained wide acceptance as the diagnostic and minimally invasive therapeutic approach for intra-luminal and extraluminal gastrointestinal, as well as various non-gastrointestinal lesions. Since its introduction, EUS has undergone substantial technological advances. This multi-centric study is a retrospective analysis of a...
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Global Bioanalytical Testing Services Market 2022-2031 by Molecule Type (Small, Large), Application (Bioavailability and Bioequivalence, PK, PD, ADME), Test Type (Cell-based, Virology, SINA, MDOV, Biomarker), Workflow Process (Sample Preparation, Sample Analysis, Others), Therapeutic Area (Oncology, Neurology, Infectious Diseases, Gastroenterology,...
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Irritable bowel syndrome (IBS) guidelines are generally developed by experts, with the possibility of a translational gap in clinical medicine. The aim of our study was to assess an Italian group of general practitioners (GPs) for their awareness and use of criteria for the diagnosis and management of IBS. For this purpose, a survey was carried out...
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Confocal laser endomicroscopy (CLE) is a diagnostic technique that enables real-time microscopic imaging during microscopic examination and evaluation of epithelial structures with 1000-fold magnification. CLE can be used in the diagnosis of various pathologies, in pneumology, and in urology, and it is very widely utilized in gastroenterology, most...
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Helicobacter pylori infection is very common and affects more than one-third of adults in Italy. Helicobacter pylori causes several gastro-duodenal diseases, such as gastritis, peptic ulcer and gastric malignancy, and extra-gastric diseases. The eradication of the bacteria is becoming complex to achieve due to increasing antimicrobial resistance. T...
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Purpose To evaluate the impact of celiac disease (CD) and the gluten-free diet (GFD) on the health-related quality of life (HRQoL) in children with CD in the United States using validated measures. We hypothesize that CD negatively impacts the child and caregivers' HRQoL. Methods Participants included children with a confirmed diagnosis of CD and...
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Promoting adult neurogenesis in the enteric nervous system (ENS) may be a potential therapeutic approach to cure enteric neuropathies. Enteric glial cells (EGCs) are the most abundant glial cells in the ENS. Accumulating evidence suggests that EGCs can be a complementary source to supply new neurons during adult neurogenesis in the ENS. In the brai...
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Isolated pancreatic metastases from melanoma are rare with high mortality rate and account for less than 1% of metastatic melanomas. Treatment options are limited with highest overall survival reported in those with complete surgical resection. Of cases reported in the literature with nonsurgical management, highest length of survival was reported...
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Cadmium, lead, mercury, and arsenic are among the most toxic environmental contaminants. Serum alanine aminotransferase (ALT) is the most common liver biomarker. This analysis aimed to explore the associations between blood cadmium, lead, mercury, urinary total arsenic, and dimethylarsinic acid and ALT elevation in adults. Data were extracted from...
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PurposeThe purpose of this study is to explore the practicality and feasibility of EPA (level 4 theory) for establishing medical training and service model in China.Method We opted for a mixed qualitative and quantitative research method, considering both explanatory and exploratory sequential designs. The qualitative research comprehended focus gr...
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IntroductionMicroRNAs (miRNAs) have been proposed as diagnostic markers, biomarkers of neoplastic progression, and possible therapeutic targets in several immune-mediated diseases. We aimed to analyze the expression profile of selected miRNAs (miR21, miR142, miR223, miR155) in patients with autoimmune atrophic gastritis (AAG), patients with non-aut...
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Secukinumab an interleukin-17 (IL-17) monoclonal antibody inhibitor is currently approved for the treatment of rheumatological conditions, such as psoriasis and ankylosing spondylitis. Lymphocytic colitis, a phenotype of microscopic colitis, is a long-term inflammatory condition, is characterized by relapsing diarrhea. The specific entity of drug-i...
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Appendicitis is one of the frequent complaints for which patients visit the Emergency Department. Appendectomy is one of the most commonly performed procedures. Stump appendicitis is a rare but severe complication of appendectomy due to the inflammation of the remaining part of the appendix. Because it is rare and partly due to physicians’ lack of...
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He ep pa at to ob bi il li ia ar ry y a an nd d P Pa an nc cr re ea as s R Re el la at te ed d D Di is se ea as se es s a an nd d T Th he ei ir r C Ca au us se es s a at t T Te er rt ti ia ar ry y C Ca ar re e H Ho os sp pi it ta al l i in n K Ka ar ra ac ch hi i ABSTRACT Objective: To determine the burden of gastrointestinal, hepatobiliary and pan...
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Published online at www.m.elewa.org/journals/ on 30 th November 2020 https://doi.org/10.35759/JABs.155.3 RESUME Objectif: Les troubles fonctionnels intestinaux correspondent à des symptômes digestifs chroniques qui orientent vers un dysfonctionnement de la partie basse du tube digestif et qui ne s'expliquent par aucune anomalie organique. L'objecti...
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Inflammatory bowel disease (IBD) diagnoses are increasing in Japan. Some patients have symptoms that are difficult to control, and further research on IBD is needed. Claims databases, which have a large sample size, can be useful for IBD research. However, it is unclear whether the International Classification of Diseases, Tenth Revision (ICD-10) c...
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Background It is known that inflammatory bowel disease is the result of a defective immune system, and immunotherapy and biological therapy have gradually become important means to treat it. This paper focused on the bibliometric statistical analysis of the current research progress to summarize the research status of this field and analyze the res...
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Background: Burnout in the field of gastroenterology is an under-researched phenomenon. So far, only a few studies have dealt with this topic. There are large geographical variations in burnout rates with 16–20% of gastroenterologists in Mexico and Germany being at risk or having burnout, 30–40% in the United Kingdom, and 50–55% in South Korea, Can...
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Adenomatoid tumors are benign neoplasms with a mesothelial origin that may be seen especially in the genital system and in many organs, but rarely in the adrenal gland. A male aged 30 years presented to the gastroenterology clinic complaining of abdominal pain and diarrhea. In abdominal computed tomography, a well-circumscribed hypodense (+50 HU) l...
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For citation: Gastroenterologìa. 2022;56(2):95-102. Резюме. Актуальність. Хронічні запальні захворювання кишечника (ХЗЗК)-одна із самих складних нозологічних груп в гастроентерології, що обумовлено постійним зростанням їх поширення, зміщенням де-бюту на більш ранній вік, підвищенням частоти тяжких ускладнених форм. Найбільш поширеним представ-ником...
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Drug-induced pancreatitis (DIP), while not a major cause of acute pancreatitis, remains a debilitating diagnosis resulting in significant patient morbidity and mortality. The diagnosis includes first diagnosing acute pancreatitis, second ruling out more common etiologies (alcohol abuse, gallstones, etc.), and third documenting a thorough history (i...
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The COVID-19 pandemic has affected emergency department (ED) usage. This study examines changes in the number of ED visits for gastrointestinal (GI) bleeding and nonemergency GI conditions, such as acute gastroenteritis (AGE) and constipation, before the pandemic and at the peak and slack periods of the pandemic in Taiwan. This retrospective observ...
Poster
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Introduction: Schizophrenia is a severe mental illness which can have a devastating impact on all aspects of an individual’s life. Substance misuse (in particular alcohol), risk of suicide, and high rates of often poorly controlled physical health conditions, have resulted in patients having a life expectancy which is reduced by approximately 15 ye...
Poster
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Introduction: Patients with Los Angeles (LA) grades C and D reflux oesophagitis are collectively considered to suffer from severe forms of oesophagitis. We aimed to determine if there are differences in clinical outcomes between those with grade C and grade D oesophagitis at index oesophago-gastro-duodenoscopy (OGD1). Methods: Patients in NHS Loth...
Poster
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Introduction: The COVID-19 pandemic has had a profound impact on inflammatory bowel disease (IBD) services and patients. Prompt management of disease flares is central in preventing admission and achieving the best outcomes. In March 2020 The Edinburgh IBD Unit established a daily flare clinic (FC) run by a consultant gastroenterologist and a speci...
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Background The Appraisal of Guidelines Research and Evaluation (AGREE) II instrument was developed to evaluate the quality of clinical practice guidelines. Evidence suggests that development, reporting, and appraisal of guidelines on surgical interventions may be better informed by modification of the instrument. Objective We aimed to develop an AG...
Presentation
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Background and aim of the Work: Malnutrition is as an important complication of liver cirrhosis with prognostic implications; a marked knowledge gap exists concerning the information needs of liver cirrhosis patients. The aim of this study is to assess nutritional status and informational needs for patients with liver cirrhosis. Subjects and Method...
Conference Paper
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Background and aim of the Work: Malnutrition is as an important complication of liver cirrhosis with prognostic implications; a marked knowledge gap exists concerning the information needs of liver cirrhosis patients. The aim of this study is to assess nutritional status and informational needs for patients with liver cirrhosis. Subjects and Method...