Fatty Acids - Science topic

Citrin deficiency (CD) is a hereditary disorder caused by SLC25A13 mutations that manifests as neonatal intrahepatic cholestasis caused by CD (NICCD), failure to thrive and dyslipidemia caused by CD (FTTDCD), and adult-onset type 2 citrullinemia (CTLN2). Citrin, an aspartate-glutamate carrier primarily expressed in the liver, is a component of the...

A novel three-dimensional MIL-101 derived porous carbon-based Ni-doped catalyst was synthesised via slow pyrolysis of Ni/MIL-101(Cr) precursor at 600 • C for 4 h. The catalytic activities were evaluated via one-pot hydrodeoxygenation (HDO) reactions by using palmitic acid (PA) as a model compound to produce green diesel within the range of a paraff...

Comparative analysis on the quality and quantity of oil extracted from two species of Groundnut seeds (Virginia specie and Spanish Specie) was conducted with the seeds obtained from Dutsin-ma local government area Katsina State and the oil present was extracted by pressing method. The proximate constituents of the Groundnut seeds were also investig...

Four structured acylglycerols with stigmasterol bonded by a succinyl linker were investigated and their stability were analyzed. Samples were heated to 60 °C and kept at that temperature to simulate storage, and to 180 °C to simulate frying conditions. The degradation of the synthesized compounds and formed derivatives was determined, and their cyt...

In recent years, replacing antibiotics in livestock and poultry feed with safer biologically active chemicals have been topic of prime interest. Antimicrobial drugs have been phased out from animal feedstuffs due to concerns that they contribute to bacterial resistance. Colistin has been added lately in the list of banned animal feed additives in I...

Intervertebral disc degeneration (IDD) is the primary cause of neck and back pain. Obesity has been established as a significant risk factor for IDD. The objective of this study was to explore the molecular mechanisms affecting obesity and IDD by identifying the overlapping crosstalk genes associated with both conditions. The identification of spec...

Cumulus cells (CCs) are pivotal during oocyte development. This study aimed to identify novel marker genes for porcine oocyte quality by examining the expression of selected genes in CCs and oocytes, employing the model of oocytes from prepubertal animals being of reduced quality compared to those from adult animals. Total RNA was extracted either...

Background Insulin resistance is linked to atherosclerotic cardiovascular diseases and stroke, whereas less is known about adipose tissue specific insulin resistance and outcomes after ischemic stroke. This study aimed to estimate the association between adipose tissue specific insulin resistance and prognosis of nondiabetic patients with ischemic...

This study explores the effects of phospholipid inclusions in the diet of Pangasianodon hypopthalmus young adults on growth and physiological parameters. Commercial diet was subdivided into four groups and top coated using phospholipid (food grade Soy Lecithin) at 0%, 2%, 6%, and 10%, of feed dry weight resulting in an equivalent of 5%, 7.39%, 11.9...

Background Fatty acid metabolism greatly promotes the virulence and pathogenicity of Mycobacterium tuberculosis ( M.tb ). However, the regulatory mechanism of fatty acid metabolism in M.tb remains to be elucidated, and limited evidence about the effects of gene mutations in fatty acid metabolism on the transmission of M.tb was reported. Results Ov...

Legumes establish symbiotic interactions with nitrogen-fixing rhizobia that are accomodated in root-derived organs known as nodules. Rhizobial recognition triggers a plant symbiotic signalling pathway that activates two coordinated processes: infection and nodule organogenesis. How these processes are orchestrated in legume species utilizing interc...

Scheelite has emerged as the primary source of global tungsten resources. The flotation separation of scheelite, which is hindered by its interface similarity with calcium-containing minerals, remains a worldwide challenge. Achieving precise regulation of interfacial physicochemical properties constitutes the scientific foundation for successful sc...

Excessive fructose intake disrupts carbohydrate and lipid metabolism in the kidney, resulting in kidney injury. Exercise has proven to improve the renal fatty acid metabolism, but the effect of various exercise intensities in preventing renal disorders is still unknown. The purpose of this study is to analyze the effect of various exercise intensit...

The metabolic state of a cell is closely related to its structure and function in adult mammalian cardiomyocytes. These adult cardiomyocytes primarily use fatty acids as an energy substrate to support heart contraction. Recently, Li and his colleagues reported that inhibiting fatty acid oxidation in cardiomyocytes keeps them in an immature state. T...

As the global population continues its rapid growth, it has become imperative to expand aquaculture in order to meet the ever-increasing demand for food. Currently, carp farming comprises roughly 50% of all inland water aquaculture production, with a range of crucial species utilized in this industry including the grass carp (Cte-nopharyngodon idel...

Each year thousands of farmed Atlantic salmon escape from seawater net pens, and introgression has been documented in a range of wild populations. Due to greater experience in the wild, escapees that have been on the run for a longer period, and successfully transitioned to a wild diet (classified: “early escapees”), could potentially have a higher...

Below we would like to present for the first time the coordination compound formed by quinazolin-4-on and indole fatty acids of cobalt (II)-nitrate dihydrate, the processes affecting the root-firing system of the varieties “Buxara-102”, “Namangan-77”, “Sultan”, “Unkurgan-1”, “C-6524”. Prior to us, synthesis processes and biological effects were stu...

Perkembangan Industri kelapa sawit saat ini di Indonesia sedang meningkat, karena kelapa sawit merupakan salah satu tanaman unggulan yang menghasilkan minyak kelapa sawit dan menjadi sumber devisa bagi negara Indonesia juga membuka lapangan kerja. Kecacatan produk sering terjadi pada setiap indsutri pengolahan kelapa sawit termasuk pada PT.XYZ, unt...

In the article, the synthesis of quinazolin-4-on, the reaction of its interaction with indole fatty acid and the synthesis of the coordination compound formed by cobalt (II)-nitrate, the biochemical action of the mulberry plant on the “morus alba” variety of the moraceae plant with the participation of various solvents, the development of root syst...

There are inconclusive results available on the association between dietary fatty acid intake and the risk of hypertension (HTN) incident. In this study, we investigate the relationship between baseline dietary fatty acids intake including polyunsaturated fatty acid (PUFA), trans fatty acids (TFA), monounsaturated fatty acid (MUFA), and saturated f...

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease. The mechanism by which medium- and long-chain triglyceride (MCT/LCT) propofol plays a role in promoting NAFLD remains unclear. In this study, we investigated the effect of MCT/LCT propofol on NAFLD progression and its mechanism of action. In Huh-7 and HepG3 cells induced by...

1H-NMR metabolomics data is increasingly used to track health and disease. Nightingale Health, a major supplier of 1H-NMR metabolomics, has recently updated the quantification strategy to further align with clinical standards. Such updates, however, might influence backward replicability, particularly affecting studies with repeated measures. Using...

In this study, biocatalysts in the form of mycelium-bound lipases of psychrotrophic and mesophilic fungi were screened for their ability to synthesize fatty acid methyl (FAME) and ethyl esters (FAEE). It has been shown that the hydrolytic activity of biocatalysts is not accompanied by their biodiesel synthetic activity. Preliminary studies showed f...

This study evaluated waste cooking oil (WCO) for environmentally friendly biodiesel production using three transesterification methods: conventional, ultrasound, and microwave. Ultrasound with NaOH as a catalyst achieved a yield of 99.7%, microwave had 94.4% conversion, and conventional had the lowest productivity at 79%. These findings demonstrate...

Hydroxycarboxylic acid receptor 2 (HCAR2) belongs to the family of class A G protein-coupled receptors with key roles in regulating lipolysis and free fatty acid formation in humans. It is deeply involved in many pathophysiological processes and serves as an attractive target for the treatment of cardiovascular, neoplastic, autoimmune, neurodegener...

Twenty-seven genotypes of varieties and advanced breeding lines were grown in two locations in three years with three replications to estimate the effects of the genotype-by-environment interaction (G × E) on the oil and oleic fatty acid contents of cultivated peanuts. Oil and oleic fatty acid contents were quantified using NMR and GC, respectively...

In this study, biodiesel was produced from Parkia biglobosa oil via optimization of transesterifcation reaction conditions, (methanol to oil ratio, catalyst concentration, reaction temperature, and reaction time) under sulphuric acid catalyst (H 2 SO 4). Te oil was frst extracted from Parkia biglobosa seeds using the Soxhlet extraction method. Te p...

Citrus aurantiifolia (Christm.) Swingle, mostly known as the Key lime or Mexican lime. In Assam, it is known as ‘Gol Nemu’, which is a small, evergreen citrus tree having significant place in the botanical geography of Assam, India. The present study is concentrated on the analysis of the nutritional components, antioxidant activity, and antimicrob...

Bu çalışma Çukurova Bölgesinde yetiştirilen mandaların süt yağ asit bileşimini ortaya koymak ve fonksiyonel bir gıda olarak önemini vurgulamak amacıyla yapılmıştır. Çalışmamızın materyalini oluşturan mandaların süt yağında en yüksek oranlara sahip yağ asitleri C14:0 (miristik asit) yaz mevsiminde %11,22 ve kış mevsiminde %11,34, C16:0 (palmitik asi...

Given the need to improve bioenergy production processes, it is necessary to focus on low-cost culture media and environmental conditions of radiation and temperature. The Scenedesmus dimorphus species was cultured in eutrophicated lagoon water and Bayfolan 0.3% as culture media under four photoperiods with the objective of evaluating the biomass p...

The study aims to determine the effect of the flipped classroom learning model assisted by pre-class quizzes on student learning outcomes of the Faculty of Mathematics and Natural Sciences, University of Mataram, in the subject of biochemistry, on fatty acid metabolism. The type of experimental research used in this study was a Quasi-Experimental D...

The feasibility of dephosphorization using the flotation process and its mechanism of high-phosphorus oolitic hematite were discussed in this paper. The results showed that phosphorus minerals mainly exist in the form of collophane, which can be divided into three types. Block collophane and band collophane could be effectively removed through flot...

The aim of the study was to examine the effect of lameness and energy status on the involution of the uterus and the resumption of ovarian cyclicity in dairy cows. Lame (lameness score of four and the presence of hoof lesions, n = 22) and sound (normal gait and the absence of hoof lesions, n = 25) multiparous cows with healthy puerperium were enrol...

Fabric softness and hand feel play a pivotal role in consumer acceptance of textiles. However, the use of conventional textile softeners has raised concerns due to their extensive chemical utilization and associated toxicity. As a result, there is a growing demand for eco-friendly and sustainable alternatives in textile finishing. This study focuse...

The presented work deals with the photocuring of telechelic macromonomers derived from plant-based fatty acids to obtain a soft polymer network. Compositions were made by mixing macromonomers with three different concentrations (0.5, 1, and 2%) of two type I photoinitiators (Omnirad 2022 and Omnirad 819). All formulations were then subjected to pho...

Objective Unsaturated fatty acids (UFA) may be related to glycometabolism. While associations between UFA intake (especially their subtype) and prediabetes or type 2 diabetes mellitus (T2DM) need to be further studied. In this study, we aimed to evaluate the potential relation of UFA with prediabetes and T2DM. Methods A total of 16,290 adults aged...

Inadequate fish consumption is common and may result from multiple reasons, especially in adolescents who are a population at particular risk of the negative consequences of not consuming the recommended amounts of fish. The aim of the study was to analyze the knowledge about fish-consumption benefits and safety in a population-based sample of Poli...

Fatty acids play various physiological roles owing to their diverse structural characteristics, such as hydrocarbon chain length (HCL) and degree of saturation (DS). Although the distribution of fatty acids in biological tissues is associated with lipid metabolism, in situ imaging tools are still lacking for HCL and DS. Here, we introduce a framewo...

De acordo com a Organização mundial da saúde, “a doença cardiovascular é a principal causa de morte no mundo, perfazendo 30% das mortes globais”, essas mortes estão relacionadas à aterosclerose, que é o acúmulo de colesterol no sangue que por consequência gera um aglomeramento de gordura nas artérias, o que ocasionará o seu entupimento. Com isso, m...

This study investigates the effects of fish oil supplementation during the periconceptional period in male mice. Specifically, it examines the impact of fish oil on intergenerational health, as determined by skeletal muscle markers. To mimic paternal obesity, thirty mice were separated into three groups with distinct dietary regimes for 10 weeks: a...

Fatty acid translocase (FAT/CD36) is a transmembrane glycoprotein belonging to the scavenger class B receptor family and is encoded by the cluster of differentiation 36 (CD36) gene. This receptor has a high affinity for fatty acids and is involved in lipid metabolism. An abundance of FAT/CD36 during exercise occurs in mitochondria and solitary musc...

Oilseed crops are rich in plant lipids that not only provide essential fatty acids for the human diet but also play important roles as major sources of biofuels and indispensable raw materials for the chemical industry. The regulation of lipid metabolism genes is a major factor affecting oil production. In this review, we systematically summarize t...

Here, we conducted the first in-depth investigation into sex effects on mitochondrial hydrogen peroxide (mH2O2) generation in hepatic tissue. Female liver mitochondria produce less mH2O2 when oxidizing pyruvate, palmitoyl-carnitine, and succinate when compared to male samples. This difference was attributed to superior coupling between fuel metabol...

Цель. Изучить вклад генетического полиморфизма Ala54Thr гена FABP2 в риск развития сахарного диабета 2-го типа (СД 2) среди популяции якутов. Материалы и методы. В исследование включили участников, заполнивших анкету, одобренную локальным комитетом по биомедицинской этике при ФГБНУ «Якутский научный центр комплексных медицинских проблем», и доброво...

Background Prolonged chronic inflammation is a risk of various chronic health disorders. Dietary patterns have been associated with inflammation. Healthy eating index 2020 (HEI-2020) has been associated with health status. However, the association of HEI-2020 and its components with systemic inflammatory biomarkers is not examined. Methods Partici...

For the continuation and evolution of life, primitive membranes formed from prebiotically available components must have fulfilled certain essential requirements. Candidate amphiphiles, such as straight-chain fatty acids, that can self-assemble into cell-like structures have been shown to be capable of performing many life-like functions. However,...

In this study, molecular dynamics simulation was used to explore the interaction characteristics of palmitic acid and CO2, and the effects of temperature and pressure on the solubility of palmitic acid in CO2 were investigated. In the range of 293–353 K and 5–30 MPa, the snapshot of palmitic acid distribution in CO2 shows that the molecular chain o...

Orexigenic neurons expressing agouti-related protein (AgRP) and neuropeptide Y in the arcuate nucleus (ARC) of the hypothalamus are activated in response to dynamic variations in the metabolic state, including exercise. We previously observed that car-nitine palmitoyltransferase 1a (CPT1A), a rate-limiting enzyme of mitochondrial fatty acid oxidati...

Introduction The prevalence of obesity is rising globally, with negative effects on the socioeconomic system. As a result of its drivers which include low-grade chronic inflammation, oxidative stress, and fatty acid metabolism, this phenotype develops metabolic anomalies that exacerbate its pathogenesis. It has been discovered that metals and metal...

Microalgae have emerged as a promising feedstock for the sustainable production of lipid-based products, including biofuels and omega-3 fatty acids, by utilizing CO2 as a carbon source. Glycerol-3-phosphate dehydrogenase (GPDH) is a vital enzyme in microalgal lipid synthesis, converting dihydroxyacetone phosphate into glycerol-3-phosphate, the init...

Saturated monocarboxylic fatty acids with long carbon chains are organic compounds widely used in several applied fields, such as energy production, thermal energy storage, antibactericidal, antimicrobial, among others. In this research, a new polymorphic phase of arachidic acid (AA) crystal was synthesized and its structural and vibrational proper...

The aim of this research was to determine the rumen fermentability of complete feed silage based on sorghum-Clitoria ternatea with the addition of concentrate containing ZnSO4 and Zn-Cu isoleucinate In Vitro. The method used in this research was an experiment with a Completely Randomized Design (CRD) for 4 treatments with 4 periods as replications....

Objective: To analyze and compare the concentrations and dietary intake of different fatty acids (FAs) in deep-fried dough sticks (Chinese fried bread) across various cities in China. Method: Sixty-one deep-fried dough stick samples were collected from five cities (Beijing, Shijiazhuang, Guangzhou, Chongqing, and Hangzhou), and the contents of FA m...

This review focuses on the potential opportunities to incorporate functional ingredients like probiotics in the dairy fat-rich matrix to develop functional foods. Many dietary guidelines and the relevant literature have in general indicated many benefits of consuming milk-fat-rich products for the human body. Milk fat contains essential nutrients,...

This study presents a simple oil dilution method, known as the bio-mix approach, to enhance the saturated fatty acid levels of non-edible oils by mixing them with highly saturated edible oils. Five raw bio-mix test samples were produced from a blend of unsaturated raw tamarind oil and saturated raw waste cooking oil at different compositions. Among...

Background: We prospectively examined the association between total fat and fatty acid intake and type 2 diabetes (T2D) among Japanese adults. Methods: This study was conducted using data from the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC). A validated food frequency questionnaire evaluated the intake of total fat and fat...

Panax notoginseng (Burk.) F. H. Chen, a species of the genus Panax, radix has been traditionally used to deal with various hematological diseases and cardiovascular diseases since ancient times in East Asia. P. notoginseng produces recalcitrant seeds which are sensitive to desiccation and difficult to store for a long time. However, few data are av...

The cultivated soybean ( Glycine max (L.) Merrill) is domesticated from wild soybean ( Glycine soja ) and has heavier seeds with a higher oil content than the wild soybean. In this study, we identified a novel candidate gene associated with SW using a genome-wide association study (GWAS). The candidate gene GmWRI14 -like was detected by GWAS analys...

Long-chain polyunsaturated fatty acids (PUFA) are critical for reproduction and thermal adaptation. Year-round variability in the expression of fads2 (fatty acid desaturase 2) in the liver of European perch (Perca fluviatilis) in a boreal lake was tested in relation to individual variation in size, sex, and maturity, together with stable isotopes v...

Melittin, a natural antimicrobial peptide, displays a broad-spectrum antimicrobial activity, which has caused increasing attention as a potential antibiotic alternative. However, melittin has not been used widely at present due to its high hemolysis and low proteolytic stability. In this study, N-terminal fatty acid was conjugated to melittin to de...

In this study, the hot smoking process and storage time of C. antalyensis was examined. The moisture, protein, ash, and fat content of fresh raw fish was 76.52±0.43%, 17.29±0.05%, 1.90±0.29%, and 1.73±0.13%, respectively. The changes in the findings of the smoked samples compared to the raw fresh sample were found to be significant (p<0.5). During...

The cluster of differentiation 36 (CD36) domain defines the characteristic ectodomain associated with scavenger receptor class B (SR-B) proteins. In bilaterians, SR-Bs play critical roles in diverse biological processes including innate immunity functions such as pathogen recognition and apoptotic cell clearance, as well as metabolic sensing associ...

Introduction Medium-chain fatty acids (MCFAs) have attracted considerable attention for preventing or improving obesity, which is a recognized risk factor for lifestyle-related diseases. Medium- and long-chain triglycerides (MLCTs) are expected to improve the metabolism of ingested long-chain triglycerides (LCTs). However, previous studies have rep...