Questions related to Exercise Intervention
I have to run a pearson correlation analysis between HPA axis markers- cortisol , ACTH and inflammatory marker IL-6(analysed through ELISA) and Depression anxiety questionnaires which were recorded at baseline and post interventions. I also need check the data for normality before running the analysis. If someone can provide an appropriate suggestion.
I conducted a big research project looking into a few different aspects of a virtual reality programme. I used 3D motion capture, heart rate monitoring and questionnaires to investigate, mental health benefits, physical health benefits and adherence. This project effectively looked into 2/3 different research questions at once. Would it be right to split these up into different papers under different titles or should I try to come up with a title that includes all aspects of this study and write it up in one paper?
If someone wants to do independent research (e.g. they design a questionnaire and ask people to take part, or they are a personal trainer and they collect data from their patients for a new exercise intervention etc) how do they publish the results if all journals require approvals from ethics committees and compliance with the Helsinki declaration?
I've heard to obtain ethics clearance from an independent ethics committee costs a few thousand dollars.
Is research publishing in a way "locked" for academic institutions only?
Their is need to understand the safety and efficacy of exercise therapy on cancer treatment–induced cardiovascular toxicity and tumor progression and metastasis in oncology practice, this can be achieved by having a fundamental knowledge of exercise prescription, dosing and personalization with regards to cancer treatment and according to global best practices.
Melancholic depression is a form of depression that should be considered separately from other forms of depression. I'm interested in why this is the case? How are the mechanisms different from other forms of depression? In addition, considering the severity of the symptoms (e.g. psychomotor, psychosis (in some cases), poor concentration, slowed speech, lack of concentration) is it worth increasing physical activity levels or altering diet? Anyone performed research in this area?
Thank you all in advance for your valuable comments.
I’ve analyzed my data using Repeated-Measures ANOVA but there is an issue that I can’t get.. In my study, I had two different groups (exercise and control) and also exercise intervention (pre and post). Shortly, in the study, I tried to reveal the effects of an exercise model on fat oxidation during exercise. To analyze my data, I’ve used Repeated-Measures ANOVA. But once analyzing the data, Repeated-Measures ANOVA shows that there is a significant difference in time (p=.025) but no differences in between the groups (time*gruops). But when I want to see which group has significant difference compared to baseline using Paired Samples T-test, there is no difference in either group. So how should I write my results or should I analyze my date with another statistical method?
I have a data set which has a within subjects variable of time, and a between subject variable of condition. My data set contains a baseline measure, followed by a repeat of this baseline measures for 7 consecutive days following an exercise intervention. However, my baseline values are different between groups so I would like to account for these when performing my repeated measures ANOVA. Therefore, is it possible to perform a repeated measures ANCOVA instead, with the baseline value as the covariate?
I am trying to find a practical way to organise the information that I have about the medication that my participants have been and are currently taking. Our study is looking at the effects that a weekly community-based exercise class has on Parkinson's disease. Every 10-12 weeks we assess our participants (different health, functional, cognitive tests and plasma/saliva samples). In order to control for the effect that medication can have, I ask our participants to report the different drugs that they are currently taking and any medication changes. However, I am finding it quite difficult to organise this data in an efficient way in excel or to track for changes and analyse it.
Is there anyone with experience in running similar longitudinal intervention trials that could suggest me a way to do it?
Are there any effects of methylcellulose ingestion on metabolism in humans? If so, is there a specific dosage at which these effects are observed? Is anyone aware of an exercise intervention study where methylcellulose was ingested prior to exercise? Any help would be greatly appreciated.
I am reaching the end of my deadline and would really appreciate some guidance -
I have one sample of subjects split in to two groups -
All participants in both groups take an outcome measure questionnaire prior to the intervention
Each group (same sample) completes a different exercise intervention -
At the end of the intervention all participants repeat the outcome measure questionnaire.
I want to see if there is a significant / statistical difference between the results of the two groups...
I am designing an exercise intervention and this outcome will help to estimate the power needed for significance.
Let's say recruitment period is X months after which randomization to exercise intervention groups occurs. The outcome is changes in depression. What are some methodological and ethical issues in choosing to defer treatment until after the recruitment period. The other option would be randomization and start of intervention as participants are recruited, but I can think of many reasons why this would be tough to do.
I have been involved in a 12 week long training program; we have some individuals who have trained with us for 6 or more 12 week cycles. We have had 0 drop-out, but loss of a 3rd+ visit due to manpower/timing. Unfortunately, some subjects only trained 2 cycles, and some 6. Any suggestions on how to disseminate some of the repeated measures information?
I’m currently investigating changes of miRNAs expression due to an exercise intervention. I analyzed a total number of 187 different miRNAs. Now I have a problem with non detected samples and their statistical evaluation. Some of the selected miRNAs showed signals only in a smaller number of samples (patients) (e.g. 35 instead of 40). Some samples showed signals only at one time point but not in the other and therefore fold change calculations are not possible.
What would be the better option for such samples, to use only the detectable values for statistics or filling in anything for the missing values?
I would be very pleased if someone can give me suggestions, how to cope with this problem.
Research question: Evaluate and synthesize randomized controlled trial (RCT) study designs that investigated the effects of physical activity on working memory performance in healthy individuals.
Main inclusion criteria stipulated (1) a healthy sample population, (2) a physical activity intervention, (3) a working memory outcome measured, and (4) a randomized control trial design.
(I graduated since submitting this journal and my ability to contact my research adviser is intermittent as she is on sabbatical, so I was hoping to get some additional insight from this thread--hope that is permissible)
1) One reviewer commented that including acute and chronic exercise interventions must be separately analyzed to which I now realize and fully agree. My question is that I only have 11 studies and 5 are acute exercise interventions. Should I simply exclude them (per reviewer's recommendation), or perhaps attempt to conduct a separate meta-analysis of the 5 acute exercise-based studies? Doing so, however, may be problematic as each of the 5 studies used different working memory measurement tools (my initial meta-analysis has subgroups where identical tests are analyzed together).
2) This question is also directly relates to my #1: by removing the 5 studies from my initial meta-analyses, some subgroups, which initially had 4 studies (3 of which were acute, for instance) now become 1 study in said subgroup. So, is there a way to resolve this new problem? Looking at previous reviews, it seems one review in particular employed a Hedges' g test that seemingly allowed for the mixing of different working memory tests (again my understanding of what Hedges' g actually is is poor to say the least).
3) Does having just 6 studies in my review (if I in fact simply exclude acute exercise intervention) limit its appeal or worthiness to the scientific community (my search strategy was very specific to begin with as I only found 11 articles over a six year span to begin with)? Currently, I do not want to exclude them, rather try to perform separate analyses.
4) Difference between moderator and mediator variables? Online sources are confusing me. I want to measure the effect of age on my variables (which is defined as a mediator) and also duration (which is defined by some as a moderator).
5) Do I utilize a sensitivity analysis for #4 or a correlational analysis or even a regression meta analysis? I used RevMan, and such additional tests would require further reading on my end.
I'm looking at using TSS in a case study intervention for a recreational triathlete. Aiming to enhance performance through a nutritional and exercise intervention.
which method is recommended to inducing diabetes type 2 in mice for studying mitochondrial dysfunction?
Drug (streptozotocin) or high fat diet?
and also any other useful information about the type and age of mice?
After inducing diabetes, 8 week exercise training will be conducted.
Thanks in advance.
We are working with primary care physiotherapy teams to evaluate exercise in thecommunity programmes that are in conjunciton with local gyms. We are looking for an ICF Participation level measure that is validated for use with stroke, PD and MS and that considers either impact of the condition or quality of life, or participation in everyday activities/interaction with family and community. Would be grateful for any suggestions of suitable measures.
Accelerometer cut points for obese populations.
Does anyone have experience in measuring physical activity by accelerometer in obese individuals?
Due to a greater body mass the energy cost of movement is greater in obese individuals. There is a clear argument for using specific cut points in obese individuals. However, there is very little in the literature on this subject.
If anyone has got experience in this, what cut points did you use and what was your rational for using these cut points?
Any thoughts or discussion on this is much appreciated
(Smaller scores mean improvement, so negative value is beneficial)
n size both groups 14
My calculation is cohen d -1.08 for treatment, and -0.6 for control.
My conclusion would be a very large effect for treatment and 1.8x more effective than control (1.08/0.6).
Is there another way of calculating or reporting the overall effect of the treatment compared to control?
I've seen others calculate overall effect by comparing the means of the post-test group, using the change in each group and the SD of the post-tests. Is that appropriate? I calculated pooled SD of post-test at 3.39. In that scenario, the overall effect would be: (1.08-.6) / 3.39 = .14..... A trivial effect?
I recently conducted a study that demonstrated great results regarding Respiratory Muscle Training (RMT) on college athletes diagnosed with Exercise Induced Asthma. One of the findings is that is potentially reduced pain in the lower back. My next study is to 'activate' sedentary people with a fear of exercise, by initially prescribing RMT. Does anyone or has anyone worked or know of any studies in this area.
Many thanks in advance
need evidence for the assessment of radicular symptoms in particular for sciatic nerve..
the purpose it to measure the difference in radicular symptoms before and after manual therapy intervention.
Our group are completing a 2015 update of our Cochrane Review titled 'Physical Fitness Training for Stroke Patients'. If you are aware of any ONGOING or UNPUBLISHED randomised trials of exercise interventions please could you let me know?
The exercise interventions we are interested in are cardiorespiratory ('endurance') training, resistance ('strength') training or a combination of both.
I am unable to find published clinical studies regarding: In the female older adult (65 & older) will aerobic versus anaerobic activities increase cognitive function? Aerobic act- meaning cardio exercises (aerobic exercises, running, step-machine, bicycling) Anaerobic act. - meaning yoga, stretching exercises (tai-chi), playing cards, Sudoku.
Over the period of time; one may get into what is called Therapeutic Automatism a kind of behavior where we tend to work like a robot or mechanically so the interesting part is how to make Physical Therapists aware about this stuff and minimize the same if possible!
Hey, let's start a physical activity program for children (age 6-13 years). I have read several articles on intervention programs, but missing information on how they have carried out.
Does anyone if there is a document supported by scientific evidence to recommend various physical activities? I need practical examples and these activities should be fun and appropriate for children.
In line with the ACSM, the objective of the program is: aerobic exercise / muscle strengthening exercise / bone strengthening exercise.
1. In our study we are going submit top Taekwondo athletes (National team) to a very high intensity intermittent intervention Taekwondo training programme (4 weeks) combined with resistant strength training and to assess the response of the organism by using physical, physiological and biochemical tests, in order to improve their individual physical performance.
2. The design of the experiment is as follows: The athletes will be used as control of themselves. They will be tested before and after the implementation of the intervention programme at the National training camp. The testing set of 40 parameters includes anthropometric, physiological measurements, physical tests, blood biomarkers and hormones. In addition a structured specific Taekwondo techniques exercise test will be employed to assess the acute response and 24 hours post-exercise blood biomarkers recovery before and after the implementation of the intervention programme. Computerised individual score charts will be implemented for assessment of the physical performance of each athlete before and after the experiment. The individual charts will be used to provide advice to the coaches for Individual adjustment aimed at improving the performance.
I would like to know the effects on the brain/quality of life/symptoms/cognition of short term exercise interventions.
I am only aware of interventions lasting 4+ weeks and I'm surprised that there is no research between acute bouts of exercise and long term interventions.
Considering the variability in the V'o2response (regarding age, sex, genetics, etc.), is there any minimal percent value of improvement which one can consider significant for a successful intervention?
Still in the early stages of research but plan on looking at the effects of consuming various amounts of CHO, and fasted state prior to HIIT, examining power output pre and post exercise intervention along with metabolic changes that occur. Sample will be based around female university athletes
Aim is to try and find an appropriate recommendation of pre HIIT CHO consumption that will allow increased performance e.g. power output and induce metabolic changes.
Any contributions or critiques are more than welcome
I am using an exercise diary to evaluate the effectiveness of my intervention. Now, I am looking for information on how valid this method is, and on how I can check validity of the information given. We know that people cheat (positively to please the researcher) or negatively (they might forget to fill up the diary). I would be glad to receive some references as well.
I am looking for evidence to prove or disprove the theory that being a member of a gym has a positive effect on physical activity and/or physical fitness, but am struggling to find appropriate terms for searching the literature. Does anyone have any references that may be a good starting point?
I have used the IPAQ-A to measure domain-specific physical activity in one intervention (n=700 approx) and one control school (n=600 approx) pre and post intervention. There was 12 months between surveys. I'm unsure about the most suitable statistical test to use. I've considered Ancova controlling for differences between groups at baseline and over time but fear that this may be inappropriate. Any help would be much appreciated.
I would like to include a patient in my walking program. However, he has fibromyalgia and experiences pain in his legs. Can he still gets benefits from walking? What training recommendations would you make?
I am using the french version of the Baecke habitual physical activity questionnaire (AQAP, 22 items) and have difficulty calculating the scores. I would like to know how you use this questionnaire, and to get an idea of scores are obtained in different studies.
A patient admitted in alcohol misuse treatment has lower limb arteritis and will do anything to avoid walking. Can one reduce pain throughout an adapted physical activity program? Is it worth promoting walking activities?
I am planning an exercise program where intensity will be set at ventilatory threshold, for alcoholic outpatients. I hope to find significant effects on exercise tolerance, physical self worth, urges to drink and regular physical activity. Any information/cases/recommendations?
Long ago known that training to failure is less effective than training without muscle failure.
I wonder if anyone can recommend me literature that compare bodybuilding training methods with current training methods using bodybuilders as study sample.
Obviously this type of training (bodybuilding) is not suitable for athletic performance (improvement in strength and power is lower than other training methods that use a lower training volume ). It is also true that a bodybuilding training is not suitable for people who want to improve their health.
It is easy to compare training methods on sedentary people (all people offer improvements in strength, power and endurance ) but I have not found such research using bodybuilders study sample undergoing training methods with different training volumes .
A bodybuilder has a very high level of training and perhaps requires large training volumes and intensity to improve. Maybe that level of training required of such high training volume.
I would like to know your opinion and if you know of recent research?
Given the known health benefits of dieting and regular physical activity, it seems strange that the Look AHEAD intervention was ineffective. One possible reason is that the participants were almost beyond the point of no-return, so to speak - in that they all had established type 2 Diabetes.
It strikes me that promoting healthy eating and regular physical activity is still worthwhile among those who are relatively healthy, as a means of maintaining health.
Should Physical Education play a significant role in contributing to a child's daily physical activity? If so, should our children have more time dedicated to PE?
Study to measure the effects of music on the stage of "brain fatigue"(during the transmission from carbohydrate based energy source to a predominantly fat based energy source which may possibly lead to depressed availability of blood glucose for optimal central nervous system functioning).
We're thinking about an incremental test where the speed will be kept the same throughout the whole test. The intensity will be increased by increasing the slope every minute until exhaustion.
Aerobic and resistance training has shown to increase brain derived growth factor and serum IGF-1 which helps in synaptic plasticity and thereby influences cognition. I want to know the specific details of exercise like intensity and duration in which BDGF and IGF-1 is increased and how long it is maintained in the blood.