Drug Addiction - Science topic

Nonneuronal cells mediate neurotransmission and drug addiction. However, the role of oligodendrocytes in stress‐induced cocaine relapses remains unclear. In the present study, we investigated the role of the oligodendrocyte‐abundant molecule crystallin alpha B (CRYAB) in cocaine‐induced conditioned place preference (CPP) relapsed by restraint stres...

Gemäß dem bio-psycho-sozialen Modell ist die Substanzabhängigkeit eine multifaktorielle Erkrankung, deren Entwicklung durch eine Reihe von Faktoren beeinflusst wird. Dazu zählen konstitutionelle Dimensionen, persönliche Merkmale und soziale Faktoren. Zahlreiche Studien haben die Rolle von Persönlichkeitsfaktoren bei der Entstehung und Aufrechterhal...

El consumo de drogas ha existido en todas las civilizaciones desde hace milenios. Los motivantes han sido diversos: creen- cias místicas, rituales tradicionales, esparcimiento, placer. La interpretación que se le ha dado a la práctica ha dependido del contexto social y del momento histórico. En la actualidad, la drogadicción se considera un problem...

El consumo de drogas ha existido en todas las civilizaciones desde hace milenios. Los motivantes han sido diversos: creen- cias místicas, rituales tradicionales, esparcimiento, placer. La interpretación que se le ha dado a la práctica ha dependido del contexto social y del momento histórico. En la actualidad, la drogadicción se considera un problem...

This study aimed to explore the experiences and motivations of drug surrenderees under the Oplan Tokhang campaign, focusing on their reasons for surrendering, the stigma they face, and their efforts toward rehabilitation and recovery. Conducted in Cateel, Davao Oriental, this study interviewed 10 participants who had graduated under the Oplan Tokha...

Objectives: The study aims to identify and analyze the most prominent language patterns in social media posts discussing drug addiction. Moreover, it seeks to examine the most commonly used metaphors and frames in social media discussions of drug addiction. Theoretical Framework: Drug addiction awareness discourse on media platforms can influence t...

Background: Homeless women who use drugs have different paths to homelessness than homeless men with substance use disorders and, therefore, have different support needs. A history of sexual and financial abuse, trafficking, and intimate partner violence, along with drug use, makes the conditions for helping women significantly challenging and diff...

Youth restiveness is a significant issue in 21st-century Nigeria, impacting national growth and development. It manifests in immoral behaviours like cultism, prostitution, sexual assaults, street violence, gambling, looting, drug addiction, and child trafficking. This menace has impacted the Mushin environment of Lagos State, posing threats to the...

The purpose of a country’s national development is to take necessary measures to reduce regional development disparities within the core-periphery structure, even in districts located within rapidly developing core regions, such as the Western Province of Sri Lanka. The present study investigated whether there is a development gap between the core...

Accumulating evidence indicates that drug addiction may lead to adaptive behavioral changes in offspring, potentially due to epigenetic modifications in parental germline. However, the underlying mechanisms remain inadequately understood. In this study, we show that paternal heroin self-administration (SA) increased heroin-seeking behavior in the F...

This paper conducts an in-depth investigation of a new spatio-temporal model for the cocaine–heroin epidemiological model with vital dynamics incorporating the Laplacian operator. The study rigorously establishes the existence, uniqueness, nonnegativity, and boundedness of solutions of the proposed model. In addition, the local stability of both dr...

Дослідження вивчає ранні стадії вживання психоактивних речовин серед осіб, які проходять замісну підтримуючу терапію метадоном. Особливу увагу вона приділяє «теорії воріт», яка стверджує, що вживання канабісу може знизити поріг подальшої залежності від інших речовин, особливо опіатів. У дослідженні взяли участь 49 учасників (77% чоловіків і 23% жін...

En los últimos años, el debate sobre la legalización del cannabis ha ido ganando fuerza en España y en el mundo. Con una demanda creciente para su uso recreativo y medicinal, pues es la droga ilegal más consumida en Occidente según los datos de la European Monitoring Centre for Drugs and Drugs Addiction (2021). Hay ejemplos internacionales como los...

Alcoholism and drug addiction affect the whole family: young, teenage, grown-up children, wives or husbands, brothers or sisters, parents or other relatives and friends. Various studies have found CBT alone to be as effective for treating less severe forms of anxiety among alcohol dependent clients when it compared to treating patients with psychoa...

Background The second wave of integrated bio-behavioural surveys was conducted among people who inject drugs (PWID) in the cities of Zagreb, Split, and Rijeka in Croatia to estimate the prevalence of HIV and hepatitis C virus (HCV) antibodies and sexual and injecting risk behaviours. Methods Respondent-driven sampling (RDS) was used to recruit a t...

The article deals with harmful habits, their use and struggle against them, the joint work of school and family in this field. A healthy person means a healthy society. The negative effects of smoking and drug addiction on our teenagers and young people are especially emphasized. Expansion of regional and international relations, exchange of experi...

Alcoholism and drug addiction affect the whole family: young, teenage, grown-up children, wives or husbands, brothers or sisters, parents or other relatives and friends. Various studies have found CBT alone to be as effective for treating less severe forms of anxiety among alcohol dependent clients when it compared to treating patients with psychoa...

HTR2C encodes the 5-hydroxytryptamine receptor 2C (5-HT2C), a G-protein-coupled receptor (GPCR) involved in serotonergic neurotransmission. It plays a crucial role in appetite regulation, mood control, and metabolic homeostasis. Alterations in HTR2C function have been linked to obesity, mood disorders, and drug addiction. This paper explores the mo...

This article offers a unique interdisciplinary theoretical examination of the stigmatisation of ‘drug addicts’ and its impacts on health and wellbeing. In the present conjuncture, drug addiction has become a metaphor for a ‘wasted’ life. The stigmatisation of addicts creates artificial monsters. They constitute matter out of place—addiction is dirt...

Background Substance Use Disorder (SUD) is a severe global problem that is influenced by both environmental and genetic factors. The genetic etiology of addiction can be complex and overlapping. This study aimed to investigate the association between two genes, ADH5 and ALDH1A1, and drug addiction in Jordanian males. Methods This study included 49...

Many service programs in organizational settings implement aftercare programs, but few talk about social rehabilitation aftercare programs for drug addicts. The purpose of this study was to provide care for ex-drug users who were not yet ready to return to their families or the home environment in which the ex-drug user was familiar and took drugs...

Globally, 50 million people are infected with hepatitis C virus (HCV), many of whom are people who inject drugs. These individuals face healthcare barriers, necessitating innovative diagnostic tools. This study evaluated the impact of cobas plasma separation cards (PSCs) for dry plasma collection in Barcelona’s outpatient drug addiction centers (CA...

This study explores the transformative effects of Dharma practices on a practitioner diagnosed with severe Borderline Personality Disorder. Following a major family crisis, she experienced intense emotional and financial strain, manifesting in symptoms such as suicidal ideation, self-harm, and substance abuse. Conventional psychiatric treatments pr...

This study addresses the challenges faced by slum communities, particularly in Satya Nagar, a neighborhood in Saidapet, Chennai. This area, like many others, reflects the struggles within society's systems and reveals the harsh socioeconomic realities of its residents. The study delves into issues such as inadequate housing, sanitation, and Socioec...

Over the last three decades, the decriminalization and legalization of therapeutic and recreational marijuana consumption have increased. Consequently, the availability of marijuana-based products associated with its therapeutic use has increased. These developments have stimulated research on cannabinoids involving a wide range of animal models an...

Background: The number of women addicted to drugs in Thailand has been steadily increasing. Data from 2021 to 2023 indicates an 8% rise in the number of women undergoing drug treatment and rehabilitation. Additionally, last year recorded the highest volume of drug seizures in Southeast Asia, highlighting a significant challenge for coordinated effo...

A primary behavioral pathology in drug addiction is the overpowering motivational strength and decreased ability to control the desire to obtain drugs, which shows some variation between different individuals. Here, using a morphine-induced conditioned place preference (CPP) model with footshock, we found that mice exhibited significant individual...

Introducción: Las adicciones más conocidas son a sustancias, pero la realidad es que también existen los comportamientos adictivos. Por esto se creó la hipótesis de que los estudiantes de kinesiología de la Universidad del Alba sede Antofagasta presentan varios tipos de adicciones siendo la más prevalente la nomofobia. Metodología: En este estudio...

Análisis del caso 3: Prevención e innovación social para el desarrollo de la juventud en el caso de los programas de Zapopan, Jalisco, México. Por: Blanca Alejandra Monterrubio Hernandez Fecha: 02/02/2025 Se pueden rescatar diferentes ideas de este programa enfocado en la disminución de la tasa de mortalidad por homicidios en un rango aproximado de...

This study addresses the challenges faced by slum communities, particularly in Satya Nagar, a neighborhood in Saidapet, Chennai. This area, like many others, reflects the struggles within society's systems and reveals the harsh socioeconomic realities of its residents. The study delves into issues such as inadequate housing, sanitation, and Socioec...

Background: Punjab, Pakistan faces a severe public health challenge from drug addiction, which impacts individuals across diverse socio-economic backgrounds. This study investigates the sociocultural, economic, and psychological dimensions that contribute to drug addiction and evaluates the effectiveness of current rehabilitation strategies. Object...

span id="docs-internal-guid-d692a933-7fff-aca9-14e4-544b4dfbdb01"> Drug addiction is a major global public health problem characterised by the compulsive use of drugs despite their harmful effects on various health dimensions. This systematic review examines the coping strategies used by individuals struggling with drug addiction and evaluates thei...

328 / 335 ‫ملخص‬ : ‫ظاهرة‬ ‫مل‬ ‫و‬ ‫هلا‬ ‫العنكبويت‬ ‫االنتشار‬ ‫نتيجة‬ ‫بلد،‬ ‫لكل‬ ‫العليا‬ ‫اهليئات‬ ‫أرهقت‬ ‫انعكاساهتا،‬ ‫و‬ ‫افعها‬ ‫ودو‬ ‫أسباهبا‬ ‫تشعب‬ ‫متشعبة‬ ‫ظاهرة‬ ‫ات‬ ‫املخدر‬ ‫تعاطي‬ ‫تعاطيها‬ ‫األكادميي‬ ‫البحوث‬ ‫فكانت‬ ‫ومروجيها،‬ ‫ة‬ ‫االدمان،‬ ‫على‬ ‫املساعدة‬ ‫وظروفها‬ ‫ابلبيئة‬ ‫تعلق‬ ‫وما‬ ‫االدمان،‬ ‫و‬ ‫للتعاطي‬ ‫افع‬ ‫ا...

The study focuses on the complex interconnection of race, sexuality, and socioeconomic background in shaping the stories of mothers struggling with addiction disorders as they attempt to recover from traumatic experiences. A sample of 45 mothers was employed in the study. Using case study analysis methodologies, the stories of 6 mothers were used a...

Análisis del caso 3: Prevención e innovación social para el desarrollo de la juventud en el caso de los programas de Zapopan, Jalisco, México. Por: Blanca Alejandra Monterrubio Hernandez Fecha: 02/02/2025 Se pueden rescatar diferentes ideas de este programa enfocado en la disminución de la tasa de mortalidad por homicidios en un rango aproximado de...

This research paper examines the expansion of Christian missionary activities from Tamil Nadu to Punjab, analyzing their impact on the socio-cultural and religious fabric of the region. It investigates the methods employed by missionaries, including social services, drug rehabilitation programs, and migration incentives, as tools for conversion. Th...

The primary objective of this study is to explore the themes of power and corruption in Steven Knight’s web series Peaky Blinders. Web series and OTT platforms have become integral to contemporary culture, growing significantly in influence over the past few years. Through this literary form, writers like Steven Knight aim to depict the socio-econo...

This study aims to examine the relationship between alcohol and drug dependence and death anxiety. To this end, the API short scale, the Abdel-Khalek Death Anxiety Scale and a sociodemographic form were administered to 69 individuals receiving support for substance dependence and 80 individuals who did not consume alcohol or drugs. According to the...

This study examines the urgent problem of drug addiction in the Jammu and Kashmir district of Srinagar, focusing on how common it is and how it relates to mental health issues. The research, which used a thorough methodology that included primary surveys and secondary data from the Government Medical College and the National Crime Records Bureau, r...

At 2 a.m. August 7th 2021, the emergency response centre of the city of Bergen, Norway, received a call from a private citizen reporting large flames appearing from a 4 floor 24 apartment municipal building housing people with drug addiction. Upon arrival 11 min later, the first responders faced a fire that had already spread and involved the whole...

Background University students confront a wide range of issues during their pursuit of education. Understanding these issues is essential for developing effective treatments and support systems. Purpose This study aims to delineate the landscape of scholarly literature pertaining to psychosocial, academic, and psychological issues among university...

Drug addiction is a chronic and potentially deadly disease that is considered a global health problem and describes the alteration of brain function by psychostimulant drugs through changes in the reward system. However, there is still no ideal strategy for the management of drug addiction. Previous studies have suggested that microglia are involve...

The neurotransmitter acetylcholine has since long been implicated in reward learning and drug addiction. However, the role of specific cholinergic receptor subtypes on different neuronal populations remain elusive. Here, we studied the function of nicotinic acetylcholinergic alpha 7 receptors (α7 nAChRs) in cocaine and food-enforced behaviors. We f...

Anti-Drug Law of the People’s Republic of China has made clear legal provisions for various measures to combat drug addiction, including voluntary rehabilitation, community rehabilitation, compulsory drug rehabilitation, and community rehabilitation. It has established a working system that combines drug rehabilitation treatment, rehabilitation gui...

Drug addiction remains one of the key problems, which troubles each nation nowadays. Though social and economic factors have been contributing to its escalation significantly, recently in recent years a marked rise with drug addiction has witnessed in Iraq. Governments and societies are therefore working hard to find ways of counteracting this tren...

تهدف هذه الدراسة للكشف عن مدى فعالية حملات التسويق الاجتماعي الذي ينتجه صناع المحتوى عبر تطبيق تيك توك في علاج إدمان المخدرات من وجهة نظر الشباب الجزائري؛ وذلك من خلال التعرف على مستوى تعرض الشباب الجزائري لمنشورات علاج إدمان المخدرات على التيك توك، وعن مستوى وعيهم بأساليب علاج إدمان المخدرات، بالإضافة إلى تسليط الضوء على مدى فعالية حملات التسويق ا...

The significant correlation between ancient medicinal practices and brain function marks a revolutionary frontier in the field of neuroscience. Acupuncture, a traditional oriental medicine, can affect brain regions, such as the hypothalamus, anterior cingulate, posterior cingulate, and hippocampus, and produces specific therapeutic effects, such as...

This paper reports an epidemiological study on substance use among college students in North India, specifically in the Kashmir Valley. A cross-sectional study used a multi-stage sampling strategy in five districts randomly selected for sample collection from 200 college students. It is a pretested, self-administered questionnaire that was derived...

The article examines the place and role of preventive activity units in the system of the National Police of Ukraine in ensuring public security and law and order, in particular in the context of modern challenges, including armed aggression on the territory of Ukraine. The author analyzes the regulatory framework that regulates the activities of p...

The research is framed within the Escuela Normal Experimental de San Antonio Matute in the municipality of Ameca, Jalisco, and within the experience of 20 years as a teacher in front of a group, it has been realized that the students of the different semesters with whom we have worked, not only in this institution but in the others in which we have...

Drug addiction is a growing worldwide problem that has serious effects on society, the economy, and health. India faces a serious problem with drug addiction, which is becoming more common among young people and other vulnerable groups. This has significant effects on mortality and morbidity. Narcotic medicines are those that cause sleep, whereas p...

Despite federal legislation intended to increase the prescribing of buprenorphine as medication for opioid use disorder (MOUD), such as the Drug Addiction Treatment Act (DATA) of 2000, most providers have continued to prescribe to some patients or to not prescribe at all. We aimed to determine the continuing barriers and supports needed for expandi...

Drug addiction, also known as substance dependence, is a chronically relapsing disorder characterized by (1) compulsion to seek and take the drug, (2) loss of control in limiting intake, and (3) emergence of a negative emotional state (e.g., dysphoria, anxiety, irritability) when access to the drug is prevented (defined here as dependence). Addicti...

Drug abuse among adolescents was difficult to identify early without official examinations, while manual methods were often inaccurate. The process of determining rehabilitation also faced challenges due to the lack of technology-based support systems capable of effectively analyzing the level of addiction and type of drug used, resulting in rehabi...

Background: Relapse is a complicated process to reiterate. A lot of biological, psychological, and social variables affect it. Objectives: The present research study aimed to examine the impact of resilience and social support (SS) on relapse periods of drug abuse. Method: A total of 300 drug users who relapsed within a year following medical treat...

Drug abuse remains one of the most complex social challenges affecting the Malay community. Despite significant development in the Asia Pacific region, Malaysia continues to face persistent issues related to drug abuse, with the problem showing little improvement since the 1970s. Youth aged 19 to 39 are particularly vulnerable, with over 50% of thi...

This paper attempts to present an overview of the profile of drug addicts in order to draw scientific generalization of the prevalence and pattern of drug abuse among youth of Kashmir. Research subjects consisted of 150 Kashmiri youths, aged 15 to 30 admitted into a three inpatient/outpatient drug de-addiction centres of three districts of Kashmir...

Introduction:This study investigates the relationship between factors such as age, gender (specifically male workers), alcohol and drug addiction, occupational risks, emotional disorders, and occupational health issues in the workplace.Methods:Data was collected through an online survey using convenience sampling from factory workers in Thailand (n...

This study was a stylistic analysis aimed at delineating the different social predicaments embedded in the ten (10) song compositions of GLOC-9. Particularly, it sought to: (1) identify the linguistic levels used in cascading the message and style of the songs along with semantics, lexicogrammar, phonology, and acoustic phonetics; (2) determine the...

Drug addiction has become a worldwide problem. Millions of people in India are addicted to drugs. Many psychological and social factors affect drug addiction. The goal of this study is to examine the relationship between people's attitudes towards drugs and psychological factors (resilience and optimism). The present study included 200 adults (100...

Introduction: addiction is classified as a brain disease, causing alterations in neurochemical functioning. It is also considered a chronic and transgenerational disease, with cultural, environmental, and individual predispositions. Psychosocial rehabilitation addresses these factors, creating collaborative spaces with a multidisciplinary team of p...

This paper reassessed and evaluate the methods of inculcating ethical and moral values in Africa. Hitherto, traditional African society had always passed on ethical and moral values to the next generation through story-telling, proverbs, moonlight play and imitation. However, with the incursion of Western views and philosophies, contemporary Africa...

Drug addiction and alcoholism are global phenomena with similar consequences worldwide, varying in magnitude based on local situations. Recently, the consumption of licit (tobacco and alcohol) and illicit (heroin, cocaine) substances has increased significantly. Rehabilitation centers are crucial to addressing and mitigating this issue. This resear...

This study explores the legislative frameworks governing drug rehabilitation and the reintegration of former drug addicts into society through a normative juridical analysis. The research examines how laws and policies influence the recovery journey, highlighting critical gaps in anti-discrimination measures, public health integration, and societal...

Introduction: The Russian aggression against Ukraine highlights the urgent need to address psychological health issues, particularly in combating addictive behaviours. This study aims to explore the psychological mechanisms underpinning the development of addiction in Ukraine’s current context.Methods: The research employed surveys (40 patients and...

This study examines the legal mechanisms for the social reintegration of drug addicts, focusing on rehabilitation as a transformative approach to enabling individuals to re-enter society as productive citizens. Using a normative juridical analysis, the research explores the alignment of national legal frameworks with international human rights stan...

Music Therapy (MT) is gaining attention as an adjunctive intervention in the treatment of Substance Use Disorders (SUD). Recent studies have shown that music therapy not only improves patients’ psychological symptoms, but may also have a positive impact on reducing drug craving [1].

Purpose: The aim of the study is to compare and determine addiction tendencies in voluntary and probation (DS) applications in Adana province located in the Mediterranean regionof Türkiye. Materials and Methods: The study was planned as prospective and cross-sectional. 1007 people who applied to the alcohol and substance treatment center within a 1...

Background Stroke is a major neurological disorder often exacerbated by substance abuse, including tramadol and cannabis. Understanding the molecular mechanisms underlying stroke pathogenesis in drug users can improve diagnosis and treatment. This study explores the roles of CYP4A11, CYP2E1, miR-27b, and miR-214-3p in the pathogenesis of stroke and...

Objective: The objective of this study was to assess the frequency and determinants of road traffic accidents among drivers of Peshawar, Kohat, and Swat Districts, Khyber Pakhtunkhwa, Pakistan. Methods: A cross-sectional descriptive study was conducted by the Department of Community Medicine at Nowshera Medical College, Nowshera, from August 2023 t...

Introduction: Substance use represents a public health problem that has increased considerably in the last years. Health institutions are scenarios that contribute to the identification of people at risk of entering the world of the addictions and, once they have done it, help them in the process of detoxification, rehabilitation and social reinteg...

Il est bien établi que le public américain a des perceptions inexactes et des attitudes négatives à l’égard des moyens de défense juridiques qui peuvent exonérer les accusés de responsabilité criminelle pour cause de troubles mentaux (c.-à-d. la non-culpabilité pour cause d’aliénation mentale), mais aucune étude n’a examiné la compréhension qu’ont...

p style="text-align: justify;">The aim of the study was to analyze dynamic changes in the motivational sphere of personality and psychoemotional features of patients with drug addiction disorders at different stages of the treatment and rehabilitation process. The study involved 226 patients: 163 men (72.1%) and 63 women (27.9%) with narcological d...

Drug addiction is a multifactorial syndrome in which genetic predispositions and exposure to environmental stressors constitute major risk factors for the early onset, escalation, and relapse of addictive behaviors. While it is well known that stress plays a key role in drug addiction, the genetic factors that make certain individuals particularly...

p style="text-align: justify;">The relevance of the chosen topic is due to the importance of studying addictive attitudes, a tendency to search for thrills and psychological defenses of personality in drug-addicted convicts, which are taken into account when compiling psychological characteristics in places of deprivation of liberty, and, further,...

Citation: Wonuola, M. M. (2024). Media and drug abuse: A critical assessment of the role of newspapers in curbing drug abuse among youth in Nigeria. Media and Communication Review, 4(2), 62-83. https://doi. Abstract The youth in Nigeria is bedeviled with series of crime-related activities, such as malpractice, bullying, and drug abuse among others....

In recent years, insomnia has gradually become a common disease in society, which seriously affects people's quality of life. At present, with the deepening of research on intestinal microbiota-gut-brain axis in Western medicine, many studies suggest that regulating the gastrointestinal tract can treat brain-related diseases. It is found that brain...

Drug abuse at the Intitusi Penerima Wajib Lapor (IPWL) Mercusuar Foundation Pekanbaru City. Group guidance can help adolescents to understand that they are not alone in facing problems and can get support from others who experience the same problems. From the results of survey observations that researchers conducted, it was found that drug abuse wa...

Introduction: Drug addiction is a widespread and global challenge that has profound effects on societies and individuals. Various factors can influence the spread of drug addiction. Therefore, this research aims to investigate the attitude towards addiction based on the sense of coherence; considering the mediating role of family adaptability. Mate...

Bifurcation analysis and nonlinear model predictive control were performed on drug addiction models. Rigorous proof showing the existence of bifurcation (branch) points is presented along with computational validation. It is also demonstrated (both numerically and analytically) that the presence of the branch points was instrumental in obtaining th...

This research aimed to discuss the impact of drug addiction and domestic violence as prominent reasons for the pronouncement of faskh (annulment) in the Terengganu Sharia Court, Malaysia as observed in decisions 11003-014-0372-2010 and 11300-014-0011-2011. The decisions are unprecedented ijtihad of the Judges because the reasons are not found in al...

El deporte es un agente formador de valores que, de primera mano, apoya en la prevención de adicciones en edades tempranas, siendo de gran ayuda en la formación de la personalidad del ser humano. Sin embargo, cuando las personas vulnerables caen en malos hábitos, como la drogadicción y el alcoholismo, el deporte adquiere un papel crucial en su proc...

CRIMINOLOGY ASPECTS OF SOCIAL DISEASES Human perception in general about health and social diseases is not unique. The ways in which social disease is understood is directly related to general social relations, that is, the behavior of a person and a certain group. Criminological studies of social diseases are more based on socio-pathological pheno...

Illicit drug and alcohol use disorder have negative impact on treatment adherence and are associated with the discontinuation of tuberculosis treatment which is a barrier to tuberculosis control. They significantly increase the risk of poor treatment outcomes in both drug-susceptible and multidrug-resistant tuberculosis patients. The main aim of th...

The subject of the article is Mikhail Bulgakov’s (1891–1940) childhood and relationships in his family of origin. Although biographers generally perceive the writer’s childhood as a happy one, certain aspects of his life, such as his drug addiction or his consistent avoidance of the subject of his own childhood in his work, may prompt a revisionist...

The endogenous dynorphin/kappa opioid receptor (KOR) system in the brain mediates the dysphoric effects of stress, and KOR antagonists may have therapeutic potential for the treatment of drug addiction, depression, and psychosis. One class of KOR antagonists, the long-acting norBNI-like antagonists, have been suggested to act by causing KOR inactiv...

Abstract: Over the past three decades, the valley of Kashmir, akin to other regions globally, has witnessed a significant escalation in the prevalence of drug addiction and suicide rates The objective of this study was to examine the influence of religious education on the resilience and character development of an individual and thereupon on the r...

Drug Abuse and suicides are global issues and are not restricted to specific borders. Annually, the global mortality rate stands at approximately one million individuals. Among these fatalities, suicides account for approximately 700,000 deaths, while drug misuse is implicated in the demise of 300,000 individuals out of a population exceeding 30 mi...

Drug addiction is now an intricate problem globally which affects people, families and communities across the globe. In Pakistan's capital territory, it is important to understand spatial epidemiology and related risk factors of drug addiction in order to develop targeted prevention and intervention strategies. This study seeks to identify the spat...

In 1971, an extraordinary book appeared. Published by an “anonymous” author, Go Ask Alice documented the story of an ordinary American girl and her descent into a world of drug addiction, prostitution, and madness. But Go Ask Alice was also a work of marketing genius. Presented as a true story, the book contained a foreword by “the editors”: 'Go As...

El film The other side (Louisiana) de Roberto Minervini se adentra en un territorio cinematográfico que navega entre lo documental explícito y lo narrativo representacional, conformando un retrato íntimo de una parte del Deep South norteamericano. En nuestro análisis del mismo, apoyado en buena parte tanto en múltiples entrevistas realizadas al dir...

One in every three ever-married women in India is a victim of spousal Violence in NFHS-5, 2019-21. In eight sister states of Northeast (NE) India, around a quarter of married women have ever experienced spousal violence. Manipur and Assam have persistently reported higher incidences in different rounds of NFHS. The study investigates the influencin...

Violence is one of the most serious violations of human rights, as evidenced by its complexity and effects. Young people’s violence is one of the most prominent types of violence in our culture. Adolescents who exhibit violent conduct are also more likely to engage in other harmful behaviours, such as chronic lying, drug addiction, reckless driving...

Injection drug abuse has become a major public health problem, the prevalence of which has increased significantly in the last decade. There are approximately 15.6 million people who inject drugs (PWID) worldwide and this may be an underestimate of the real problem as the use of injection drugs is an illegal and stigmatized practice, making data co...

The elevating population pressure leads to the mal-nutrition and sacristy of food, medicine as well as it results in an increase in industrialization followed by increase in pollution hazards. Due to nutritional deficiency and pesticide residues on vegetables and food products leads to the development of carcinogenic effects on the local communi...

Drug addiction is rife in Nepal, with a high relapse rate following treatment. Apart from basic psychosocial support, there are no evidence-based aftercare services for individuals in recovery. Recently, mindfulness-based interventions have shown promising results in preventing relapse. We discuss the context, challenges and opportunities of organi...

Objective: The aim of this study is to explore the efforts of public health professionals, including scientists, narcologist-practitioners, and teachers, in addressing the issues of alcoholism and drug addiction. This includes promoting medical and legal knowledge, as well as providing preventive and therapeutic measures. Methods: The study investi...

People who inject drugs (PWIDs) experience high rates of hepatitis C virus (HCV) infection, primarily due to needle sharing and limited healthcare access, resulting in a disproportionate disease burden within this population. This prospective study evaluated treatment outcomes in 432 adult patients with chronic hepatitis C (CHC) treated with direct...