Questions related to Disease Diagnosis
I've been interested in COVID stuff recently. Most of the current detection/diagnosis strategies need amplification. I can understand that RT-PCR can probably break the capsid because of the high-temperature processes. But how does that work for isothermal methods like RT-LAMP, since the temperature is not that high?
Also, if we want to directly detect or do something with the viral RNA, do we need to break the capsid and release the RNA? If yes, is there any established protocol? Many thanks!
I am developing a research protocol to test the inter-rater reliability of a measurement tool for learning. I see that the minimum acceptable kappa value could differ from discipline to discipline depending on the degree of inter-rater agreement required? for instance, a higher degree might be needed in medicine/disease diagnosis than in education?
We are working on heart disease diagnosis and for this purpose we will required a database so it could be useful for us to develop an expert system.
I have a special issue entitled "Deep Learning for Chronic Disease Diagnosis, Prediction, Monitoring, and Treatment."
The issue has the following link:
You are welcome to submit your research papers in this issue. Please note that the Diagnostics
Journal has 3.110 impact factor.
The research question is: Does gender influence stress levels four month post-diagnosis of cancer?
Hello everyone! I am currently doing an analysis of the occlusal analysis. Now I have a pressure sensor for the mouth, just like Tek-scan. I am trying to link stress analysis with a certain oral disease (such as Temporomandibular joint disorder syndrome-TMD, periodontitis) and establish a series of graded diagnostic criteria or rate the reliability of implants based on occlusal analysis. Sorry I don’t know a lot about stomatology.Is there any research on the relationship between occlusal analysis and oral disease diagnosis, rather than just outputting bite force data?Thanks!
The IoT Enabled ECG Signal Quality Assessment is becoming integral part in the Medical field.
Dear Colleagues ..
I'm working on dental diseases diagnosis based Machine learning by using OPG medical images. I need to access real database that includes OPG images. Any Kind replays will be very important to my work and will be very appreciated.
When I did nested PCR for WSSV diagnosis, i used two tissues gills and pleopod, both are target tissues for virus. I got positive band in the second step only and for pleopod only not for gills. What may be the reason?
I am working on leaf disease diagnosis using machine learning techniques and looking for hyperspectral of multispectral database of specific crop. Kindly help me and tell the resource from where I can get database which I can use for my research work
Aspiration pneumonia is a common disease in the world. Clinician may frequently diagnose this disease by clinical symptoms, radiological findings, and lab data. But, I don't know the standard criteria of diagnosing aspiration pneumonia. Does anybody know an international criteria of this common disease ?
Previously to understand the concept of health disease medical model is applied, where health professional concerned about the disease, diagnosis and drugs, but now this model is replaced by the bio-psycho social model, in which we should include the psychology and social factors along with the biological as it is also the part of the nature.
We have diagnosed a girl with McKusick-Kaufman syndrome (MKS) based on clinical presentation with hydrometrocolpos, polydactyly, and congenital heart disease. We want to confirm the diagnosis at the molecular level, but we do not know where to do this.
Has anyone suggestions about laboratories to perform mutational analysis of MKKS gene?
Generally, when no need to choose an appropriate model, we can just split data set into only training data and test data. But in medical data mining specifically in prediction, the result is very sensitive to model selection. If the previous works addressed an appropriate model for a specific disease, can we ignore the validation phase and split split data set into only training data and test data?
The insidious onset of acromegaly causes delay in diagnosis. Given the retrospective nature of the assessment of this delay, all measures are prone to recall bias.
I want to know the relation of Molecular PCR testing and Pathogen Associated Molecular Pattern detection by reproductive immunology for MTB detection in Genital Tuberculosis.
There have been many conflicting view about the test. Recently I have noticed that PCR negative sample often is PAMP positive and clinical there is no MTB symptoms.
Is this largely possible that due to technical constraints a PCR negative sample my come PAMP positive without any clinically relevant symptoms?
I want know how many genes for responding cardio vascular diseases, diagnosis and what are the genes expressed myocardial infarction and coronary artery disease can tell me whom are working these relevant working
I am drawing the Disease-free survival (DFS) and overall survival (OS) curves according to Kaplan–Meier estimates and compared by log-rank tests.
I was using the median as numerical value ( median<High and median>low). But in some paper, they do not use median. I do not have enough knowledge in biostatistics.
Please give me a good advice what is the best way to fix the numerical value to devide High and Low.
I am looking for a person to collaborate with in a research to develop an efficient and a robust automatic method for Malaria diagnosis, which advances the current state-of-the-art technology. The method uses the blood slide images to enumerate the number of infected and healthy RBCs. But, these results should be validated against the traditional approach to diagnose Malaria.
Currently, the model has been theorized and what is missing is to have as many experiments as possible from real lab data. In the future, the research may proceed to incorporate the proposed model into some portable devices, like mobile phones, such that individuals may be able to self-determine their parasitemia levels without visiting hospitals (in situations where patients do not have access to hospitals).
Just as a disclaimer, the research is not funded by any Organization or Company, and is personal for now. The only thing I can guarantee at the moment is co-authorship (if an individual would like to be included in the authorship page). We are about four engineers, and more details of the method may be revealed when we set some terms with a volunteer. Below are the things we specifically require in the research:
- A Person who will have access to about 200 blood-smear images from suspected patients of Malaria.
- A person who can perform a manual count of the infected RBCs, and total RBCs, per every sample image
- A Person who may provide his time to review the final paper, particularly in a section with medical information, to ensure that it seats well before submission.
Just for emphasis, now the research is in the simulation stage; the later stage of implementing the algorithm in the real hardware will be considered the next phase of the research.
Anyone with interest, you are kindly welcome. You may either use this forum for communication, and all comments will be noted. Alternatively, you may use private message me
I'm facing two different questions.
(1) Are plants produced by conventional breeders' breeding processes (i.e. cross, select, etc), patentable? This is now before the EBA at the European Patent Office (I believe G-1/98 is wrong), and
(2) Does a method of diagnosis in medicine have to be of a disease condition, and does there have to be a cure available if suffering from the condition is diagnosed? (I believe G-1/04 is wrong). This is now the subject of an opposition.
On both, I have to put my case together in the next week or so. In neither case do I have a financial interest - I just want the law to get back on track.
Can anyone help? Is anyone willing to help? More particularly, are there any non-OB/GYN medics out there who would be willing to talk?