Digestive System Diseases - Science topic

Objectives Abdominal palpation is an essential examination to diagnose various digestive system diseases. This study aimed to develop an objective and standardized test based on abdominal palpation simulators, and establish a credible pass/fail standard of basic competency. Methods Two tests were designed using the newly developed Jucheng abdomina...

Georgiy Yosypovych Burchynsky (1908 — 1993) — Doctor of Medical Sciences, Professor, Honored Scientist of Ukraine, and laureate of the State Prize of Ukraine. G. Y. Burchynsky, throughout his life, was brought up on the traditions of the Kyiv therapeutic school. A close relationship with the Kyiv therapeutic school largely determined his personalit...

tsRNAs are small non-coding RNAs originating from tRNA that play important roles in a variety of physiological activities such as RNA silencing, ribosome biogenesis, retrotransposition, and epigenetic inheritance, as well as involvement in cellular differentiation, proliferation, and apoptosis. tsRNA-related abnormalities have a significant influen...

Background Growing evidences of recent studies have shown that gut microbrome is causally related to digestive system diseases. However, causal relationships between the gut microbiota and the risk of digestive system diseases still remain unclear. Methods We utilized identified gut microbiota based on class, family, genus, order and phylum inform...

Background: Gastrointestinal disease is a significant global health problem. Symptoms related to digestive system diseases negatively affect quality of life and impose a significant economic impact. Upper gastrointestinal symptoms are common in the Ethiopian population, and the associated pathologies are diverse. Real-time endoscopic visualization...

Excessive intake of sugar, and particularly fructose, is closely associated with the development and progression of metabolic syndrome in humans and animal models. However, genetic disorders in fructose metabolism have very different consequences. While the deficiency of fructokinase, the first enzyme involved in fructose metabolism, is benign and...

Background. Proton pump inhibitors (PPIs) are widely used to treat digestive system diseases. Previous studies have suggested conflicting results between PPI treatment and the risk for digestive tract cancers (DTCs). This study aimed to assess the effect of PPI use on DTCs by data mining of the FDA Adverse Event Reporting System (FAERS) database. M...

The current study focused on the latest status of gastrointestinal, urinary tract, and hepatobiliary diseases, which might be induced by stress in cats following the SARS-CoV-2 pandemic in Hatay province in Türkiye. The study looked at post-pandemic (June 2021-June 2022) diagnosis data of cats (n:147) with gastrointestinal, urinary tract, and hepat...

Purpose To explore the incidence, risk factors, management and prognosis of systemic complications after ophthalmic surgeries. Methods A retrospective review of hospitalized patients undergoing ophthalmic surgeries between 2012 and 2022 at Peking Union Medical College Hospital was performed to summarize and analyse the postoperative systemic compl...

Coriander (Coriandrum sativum L.), one of the annual herbaceous plants widely used as a medicinal and aromatic herb, is used as flavor and aroma, to treat digestive system diseases, as antipyretic, etc. Salinity, which is one of the soil quality index parameters, is one of the most important abiotic stress factors limiting the production of agricul...

Simple Summary Periodontitis, a chronic inflammatory disease of the gums, and the oral microbiome have been recently implicated in the development of various cancers. Due to the mounting interest in the oro-intestinal axis, this review summarizes the current evidence linking periodontitis and oral bacteria to digestive tract cancers. The oral micro...

Chronic gastritis (CG) is a common clinical digestive system disease, which is not easyily cured and is prone to recurrence. Traditional Chinese medicine (TCM) plays a significant role in the treatment of CG and has attracted increasing attention for clinical applications. In recent years, a large number of reports have shown that TCM has good ther...

Acute pancreatitis (AP) is a type of digestive system disease with high mortality. Previous studies have shown that gut microbiota can participate in developing and treating acute pancreatitis by affecting the host’s metabolism. In this study, we followed 20 AP patients to generate longitudinal gut microbiota profiles and activity during disease (b...

Introduction Gallstones are a common digestive system disease. Aim To assess the effects of laparoscopic and choledochoscopic gallbladder-preserving cholecystolithotomy on the levels of operation indicators, gallbladder function, and cholecystokinin type-A receptor (CCKAR) in patients with gallstones. Material and methods The medical records of 1...

Aim: To investigate whether and which diseases co-occur with periodontitis (PD) to assess the prevalence of comorbidities and multimorbidity and to identify patterns and profiles of comorbidity and multimorbidity and the influence of demographic and lifestyle factors to identify distinct groups of multimorbid patients. Materials and methods: A d...

A few main directions can be distinguished in the scientific and practical activities of M. M. Gubergrits. Even his first studies contributed to the history of the development of domestic cardiology. He continued the work started by V. P. Obraztsov on the III normal heart sound, studied changes in heart tones and the formation of a gallop rhythm, t...

Endoscopic ultrasound (EUS) has emerged as a widely utilized tool in the diagnosis of digestive diseases. In recent years, the potential of artificial intelligence (AI) in healthcare has been gradually recognized, and its superiority in the field of EUS is becoming apparent. Machine learning (ML) and deep learning (DL) are the two main AI algorithm...

Objectives To develop and validate European entrustable professional activities (EPAs) for sub-specialised hepatobiliary and gastrointestinal (HB/GI) diagnostic imaging. Materials and methods Both European Society of Radiology and national curricula in HB/GI diagnostic radiology were thoroughly reviewed, resulting in preliminary EPAs drafted by a...

Background: Cholelithiasis is a common digestive system disease that imposes major burden on patients and society. Investigating the relationship between dietary factors and cholelithiasis risk can provide a basis for disease prevention. Previous studies on milk intake and cholelithiasis incidence have been limited.Therefore, the aim of our study...

CAG is a burdensome and progressive disease. Numerous studies have shown the effectiveness of RUT in digestive system diseases. The therapeutic effects of RUT on MNNG-induced CAG and the potential mechanisms were probed. MNNG administration was employed to establish a CAG model. The HE and ELISA methods were applied to detect the treatment effects....

Ferulopsis hystrix is a perennial plant of the Apiaceae family. In Buryat and Mongolian medicine, it is used as a substitute for Costus speciosus roots (ru rta), and in Tibetan medicine, it is used to cure digestive system diseases and used as a wound-healing agent. However, its metabolites and their bioactivities are still poorly understood. High-...

Purpose: To establish a concise and easy-to-understand reference manual for outpatient primary care providers, promoting correct diagnosis of digestive system diseases and rational antimicrobial use. Methods: The establishment of the manual encompassed two processes: the development of a draft manual and the validation of the manual. The develop...

Objectives Digestive system diseases have evolved into a growing global burden without sufficient therapeutic measures. Lactobacillus reuteri ( L. reuteri ) is considered as a new potential economical therapy for its probiotic effects in the gastrointestinal system. We have provided an overview of the researches supporting various L. reuteri strain...

Non-wood forest products (NWFPs) are collected or harvested for commercial and medical purposes from forests. These plants can be diversified into wild food plants, medicinal and aromatic plants, bulbous plants, mushrooms, dye plants and honey. The aim of this study is to assess the demand of consumers who buy medicinal plants in Istanbul and to re...

Introduction Many studies have revealed the effect of medical history on dementia. The aim of this study was to explore the relationship between the history of disease and onset of dementia. Methods This was a multi-center, cross-sectional study, with 2595 older adults enrolled. The onset of dementia was evaluated with Revised Hasegawa Dementia Sc...

Background: Upper gastrointestinal neoplasia mainly includes esophageal cancer and gastric cancer, both of which have high morbidity and mortality. Lymph node metastasis (LNM), as the most common metastasis mode of both diseases, is an important factor affecting tumor stage, treatment strategy and clinical prognosis. As a new fusion technology, en...

This paper used two waves (2016 and 2018) of longitudinal data from the China Families Panel Survey (CFPS) to analyze the economic impact of Non-communicable chronic diseases (NCDs) on individual earned income using propensity score matching and difference in difference (PSM-DID) methods to control for potential confounding. The occurrence of a NCD...

Intra-organism biodiversity is thought to arise from epigenetic modification of our constituent genes and post-translational modifications after mRNA is translated into proteins. We have found that post-transcriptional modification, also known as RNA editing, is also responsible for a significant amount of our biodiversity, substantively expanding...

Intra-organism biodiversity is thought to arise from epigenetic modification of our constituent genes and post-translational modifications after mRNA is translated into proteins. We have found that post-transcriptional modification, also known as RNA editing, is also responsible for a significant amount of our biodiversity, substantively expanding...

Piper nigrum , black pepper, has been widely used in traditional medicine to treat fevers and digestive system disease and is also applied to treat cancer in China. This study evaluated the breast cancer-preventive effect of a low piperine Piper nigrum extract (PFPE or LP-PE). Our findings showed that the incidence of tumors was 70% in the control...

To limit the epidemic of COVID-19, most countries and regions have adopted the policy of quarantine, providing an opportunity for the development of telemedicine. This study aims to develop a telemedicine system within a quarantined district and validate its effectiveness and safety in managing a variety of diseases within the population. Appling t...

The gut microbiota are not only related to the development and occurrence of digestive system disease, but also have a bidirectional relationship with nervous system diseases via the microbiota-gut-brain axis. At present, correlations between the gut microbiota and neurological diseases, including stroke, are one of the focuses of investigation and...

Olexander Oleksiyovych Shalimov (1918—2006), Academician of the Academy of Sciences of the Ukrainian SSR, Hero of Socialist Labor, laureate of the State Awards of the USSR and the Ukrainian SSR, an Honorary Doctor of the RSFSR, an Honorary Scientist of the Ukrainian SSR, and a famous Soviet scientist and surgeon. He made a great contribution to the...

Viral gastroenteritis is the most common viral illness that affects the gastrointestinal (GI) tract, causing inflammation and irritation of the lining of the stomach and intestines. Common signs and symptoms associated with this condition include abdominal pain, diarrhea, and dehydration. The infections commonly involved in viral gastroenteritis ar...

Background: Metabolic syndrome (MetS) has been associated with digestive system diseases, and recent observational studies have suggested an association between MetS and cholelithiasis. However, the causal relationship between them remains unclear. This study aimed to assess the causal effect of MetS on cholelithiasis using Mendelian randomization...

Background: Langerhans cell histiocytosis (LCH) is characterized by dysregulated proliferation of LCH cells and subsequent organ infiltration. Clinical manifestations vary and range from a single system unifocal bone disease to multisystem LCH with risk organ involvement. The prognosis is in majority of cases favourable, but some LCH survivors expe...

Globally, obesity is a health crisis. Obesity raises the risk of CVD, T2DM, musculoskeletal problems, digestive system diseases, respiratory issues, and psychological issues that might interfere with daily life. It might kill you. Overweight and obesity are health risks, according to the World Health Organization. A BMI of 30 kg/m2 or higher...

Aims: Gastroesophageal reflux disease (GERD) is a common health problem worldwide. Previous studies have reported that central obesity associated with visceral steatosis is an important problem in digestive system diseases, especially reflux-related diseases. This study aimed to examine the effect of body fat distribution on the development of eros...

Annotation. The study aimed to analyze references in the scientific literature on hard dental tissue damage and periodontal and oral mucosal diseases in patients with concomitant gastrointestinal tract pathology. We used the bibliosemantic method to identify the status of the outlined issues and analysis of the scientific research data. Based on da...

BTB and CNC homologous (BACH) proteins, including BACH1 and BACH2, are transcription factors that are widely expressed in human tissues. BACH proteins form heterodimers with small musculoaponeurotic fibrosarcoma (MAF) proteins to suppress the transcription of target genes. Furthermore, BACH1 promotes the transcription of target genes. BACH proteins...

São Paulo state is one of the country’s largest producers of beef and milk, and the midwestern region plays a key role in this production, as half of São Paulo’s cattle herd is found in this region. These numbers alone demonstrate the importance of livestock in this region. Therefore, this study aimed to describe the main epidemiological and clinic...

Digestive system diseases can affect individuals of all ages and require comprehensive and specialized care. Effec­tive management of digestive system diseases requires a multidisciplinary approach, involving healthcare professionals with specialized skills and knowledge. Nurses play an integral role in this approach, working in collaboration with...

In his doctoral thesis, young M. D. Strazhesko described a number of important physiological patterns in the activity of the dog’s intestines. M. D. Strazhesko was one of the first authors in world literature to present information about the nature of the juice in different parts of the colon, especially in the caecum. At the same time, his attenti...

Objective: From the perspective of metabolomics, this study compares the metabolomics characteristics of feces and urine between children with spleen-deficiency and healthy children to explain the scientific connotation of children with spleen-deficiency susceptibility to digestive system diseases from the metabolic level and provide a scientific...

Although numerous epidemiological studies have demonstrated a relationship between environmental factors and chronic diseases, there is a lack of comprehensive population health vulnerability assessment studies from the perspective of environmental exposure, population sensitivity and adaptation on a regional scale. To address this gap, this study...

Unlabelled: Wumei Bolus is a traditional Chinese medicine prescription, first appeared in Shennong Bencao Jing. Modern pharmacology believes that Wumei Bolus has antibacterial, antitussive, sedative, antiviral and anti-tumor effects, and plays a therapeutic role by acting on multi-target/multi-pathway. Moreover, it has great advantages in digestiv...

Gadoxetic acid is an MRI contrast agent that has specific applications in the study of hepatobiliary disease. After being distributed in the vascular and extravascular spaces during the dynamic phase, gadoxetic acid is progressively taken up by hepatocytes and excreted to the bile ducts during the hepatobiliary phase. The information derived from t...

Acrolein, a highly reactive α,β-unsaturated aldehyde, is a compound involved in the pathogenesis of many diseases, including neurodegenerative diseases, cardiovascular and respiratory diseases, diabetes mellitus, and the development of cancers of various origins. In addition to environmental pollution (e.g., from car exhaust fumes) and tobacco smok...

Fructus Aurantii (FA) is the dry and immature fruit of Citrus aurantium L. and its rutaceous cultivars. FA has been widely used to treat digestive system diseases since ancient China, and it promotes gastrointestinal (GI) motility in functional dyspepsia (FD), but its potential therapeutic mechanisms remain unclear. We examined the effects of FA et...

Background: Gastric precancerous lesions (GPL) precede the development of gastric cancer (GC). They are characterized by gastric mucosal intestinal metaplasia and dysplasia caused by various factors such as inflammation, bacterial infection, and injury. Abnormalities in autophagy and glycolysis affect GPL progression, and their effective regulatio...

Vasyl Parmenovich Obraztsov (1849 — 1920) was an outstanding therapist, Professor of Medicine, and innovator in the field of techniques for diagnosing diseases of the cardiovascular and digestive systems. The research interests of V. P. Obraztsov were mainly focused on studying the most important issues in general and specific gastroenterology and...

The aim of this study is to evaluate the demand of consumers who buy medicinal plants in Istanbul and to reveal the relationships between the variables affecting the demand. For this purpose, face-to-face interviews were conducted with consumers (n=384) who purchased medicinal plants in 20 randomly selected districts of Istanbul. Descriptive analys...

Pseudomembranous colitis is severe inflammation of the inner lining of the colon due to anoxia, ischemia, endothelial damage, and toxin production. The majority of cases of pseudomembranous colitis are due to Clostridium difficile. However, other causative pathogens and agents have been responsible for causing a similar pattern of injury to the bow...

The gut microbiota is a complex ecosystem that has coevolved with the human body for hundreds of millions of years. In the past 30 years, with the progress of gene sequencing and omics technology, the research related to gut microbiota has developed rapidly especially in the field of digestive system diseases and systemic metabolic diseases. Mechan...

Aims: Rheumatoid arthritis (RA) is a common chronic immune disease. Berberine, as its main active ingredient, was also contained in a variety of medicinal plants such as Berberaceae, Buttercup, and Rutaceae, which are widely used in digestive system diseases in traditional Chinese medicine with anti-inflammatory and antibacterial effects. The aims...

Background: The rapid spread of coronavirus disease 2019 (COVID-19) has attracted worldwide attention. There were also reported gastrointestinal symptoms in patients with COVID-19. This work aims to analyze the global research trends in COVID-19 and digestive disease. Methods: The related papers on COVID-19 and digestive disease were identified...

Besides causing severe acute respiratory syndrome (SARS), SARS‑coronavirus 2 (SARS‑CoV‑2) also harms the digestive system. Given the appearance of numerous cases of SARS‑CoV‑2, it has been demonstrated that SARS‑CoV‑2 is able to harm target organs such as the gastrointestinal tract, liver and pancreas, and either worsen the condition of patients wi...

Background Mental and physical health conditions are frequently comorbid. Despite the widespread physiological and behavioral changes during pregnancy, the pattern of comorbidities among women in pregnancy is not well studied. This study aimed to systematically examine the associations between mental and somatic disorders before and during pregnanc...

The study aimed at identifying the plants of Bousaada district of M'sila province, South East Algeria, used by the local people as traditional medicines and analyzing their use value. The ethnomedicinal use information was collected by interviewing local informants using structured questionnaires through regular field surveys. A total of 193 specie...

Gegen Qinlian Decoction is one of the commonly used classical prescriptions, which consists of four herbs: Gegen (Puerariae Lobatae Radix), Huangqin (Scutellariae Radix), Huanglian (Coptidis Rhizoma), and Zhigancao Glycyrrhizae Radix et Rhizoma Praeparata cum Melle. The clinical application experience of Gegen Qinlian Decoction is as follows: first...

The article presents the results of an empirical study of the peculiarities of the attitude of the family on the formation of health and tendencies to formation diseases of the digestive system in school age children. The study was conducted on a cohort of 1100 children of school age of younger, middle and senior schools’ classes of Kyiv and Lutsk...

Introduction Many studies have revealed the effect of medical history on dementia. The aim of this study was to explore the relationship between the history of disease and onset of dementia. Methods This was a multi-center, cross-sectional study, with 2595 older people enrolled. The onset of dementia was evaluated with Revised Hasegawa Dementia Sc...

Background Although regulatory changes towards correcting the underrepresentation of women in randomized controlled trials (RCTs) occurred (National Institutes of Health 1994), concerns exist about whether an improvement is taking place. In this systematic review and meta-analysis, we aimed to assess the inclusion rates of women in recent RCTs and...

Objectives: We tended to explore the association of indoor air pollution (IAP) and non-neoplastic digestive system diseases (NNDSD) among the Chinese middle-aged and older population. Methods: From 2011 to 2018, we included 7884 NNDSD-free adults from the China Health and Retirement Longitudinal Study (CHARLS). Physician-diagnosed NNDSD was obtaine...

Toxocariasis is common among children and causes digestive diseases. The aim of the work was to study the development of toxocariasis in children with digestive diseases. The serum levels of specific IgG to Toxocara canis and Ascaris, levels of IL-4 and TNF-α were determined in 63 children. In addition, tests for parasites and a retrospective surve...