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Publications related to Dermatology (10,000)
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Article
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Background: Neurofibromatosis type 2 (NF2) is characterized by bilateral vestibular schwannoma (VS) more often in adults but a severe paediatric form with multiple neurological tumours is also described. In this population, a early diagnosis is important to prevent the onset of neurological complications but is difficult, particularly without a fa...
Article
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Teledermoscopy, or the utilization of dermatoscopic images in telemedicine, can help diagnose dermatologic disease remotely, triage lesions of concern (i.e., determine whether in-person consultation with a dermatologist is necessary, biopsy, or reassure the patient), and monitor dermatologic lesions over time. Handheld dermatoscopes, a magnifying a...
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Background In late 2019, Coronavirus disease 2019 has been declared as a global emergency by World Health Organization. Hopefully, recent reports of effective and safe vaccines were welcomed, and approved on emergency base. Millions of recipients had received one of the approved COVID 19 vaccines, with lots of adverse events recorded global wide....
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Amelanotic malignant melanoma (non-pigmented melanoma) is a subtype of skin melanoma with little or no pigment on visual examination and is one of the most difficult-to-diagnose clinical conditions. It can mimic benign and malignant variants of both melanocytic and non-melanocytic lesions. Amelanotic melanoma (AM) accounts for 1.8 to 8.1% of all me...
Article
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Adapalene is used for treatment of acne vulgaris, a common dermatological disease. Nano-based carriers have been developed to improve solubility and bioavailability of adapalene and other acne treatment drugs. In our previous report, tea tree oil nanoemulsion containing adapalene gel (TTO NE + ADA Gel) showed appropriate physical and biological pro...
Article
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Background Ablative lasers have long been considered an unfavorable option for melasma in patients with skin of color and continue to be underutilized. Objective To evaluate the safety and outcomes of ablative fractional CO2 lasers on refractory melasma in patients with skin of color. Methods A retrospective chart review of 12 patients from a sin...
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Objective A complete toxicity profile, toxicity profile, and safety ranking of immune checkpoint inhibitors (ICIs) for treatment of advanced non-small cell lung cancer (NSCLC) will be provided in this network meta-analysis. Methods We searched 14 randomized clinical trials (RCTs) including 9572 NSCLC patients by PubMed, EMBASE, Cochrane, and Clini...
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Background Notalgia paresthetica (NP) is a chronic sensory neuropathy that causes intense pruritus, typically affecting the upper portion of the back and lasting for months to years. The impacts of pruritus and the full symptom experience are not well documented. Objective To describe patients’ NP symptom experience and the impacts of living with...
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The diffusion of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inducing coronavirus disease 2019 (COVID-19) has increased the incidence of several dermatological disorders, including hair loss (HL). This article aims to review the literature regarding the incidence of HL and telogen effluvium (TE) in COVID-19 patients and critically...
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Atopic dermatitis (AD), chronic hand eczema (CHE), and urticaria are common inflammatory skin diseases among adolescents and associated with air quality. However, the synergistic effects of ambient air pollution and second-hand smoke (SHS) have been unclear. We conducted a cross-sectional study including 20,138 Chinese college students where dermat...
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Background Image-based cancer classifiers suffer from a variety of problems which negatively affect their performance. For example, variation in image brightness or different cameras can already suffice to diminish performance. Ensemble solutions, where multiple model predictions are combined into one, can improve these problems. However, ensembles...
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Vitiligo is a skin disease associated with significant psychiatric comorbidities. Affective temperaments represent the inherited foundation of personality and represent the biologically stable part of emotional reactivity. Studies assessing the temperament profile of patients with vitiligo are still scarce. This was a cross‐sectional study enrollin...
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Background Diagnosis and treatment of skin disease in sea workers is an unmet need. The purpose of this study is to highlight how remote management of dermatological conditions appears inadequate in this scenario. Objective This study aimed to identify the best epidemiology for seafarers' diseases and analyze the adequacy of medical assistance in...
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Background: The new coronavirus COVID-19 pandemic has had an unprecedented impact on global health and economic growth. A widely used vaccine is the weakened inactivated severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) virus (Sinopharm). Following major SARS-CoV-2 vaccination campaigns, cutaneous symptoms are on the rise. Methods: This...
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Repair of auricular defects following tumor removal can be challenging. Many techniques have been described, but the literature lacks a comprehensive review of these methods. To perform a systematic review to compile and describe methods of reconstruction for post-surgical defects on the ears, eight databases were searched using terms related to ea...
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Banana leaves as a traditional dressing for pemphigus: a case report Pemphigus vulgaris is one of the most common autoimmune blistering disorders, with most patients presenting in late stages with severe and extensive erosions over the skin. Along with systemic management of the disease, it is important to provide local wound care to prevent second...
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COVID-19 can present with a range of skin manifestations, some of which specific of the pediatric age. The aim of this systematic literature review was to determine the type, prevalence, time of onset, and evolution of cutaneous manifestations associated with COVID-19 in newborns, children, and adolescents, after excluding multisystem inflammatory...
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Climate is changing, and the time to act is now. The worldwide increase of greenhouse gas (GHG) emissions and the many deaths seen during the COVID-19 pandemic, caused by an unknown virus and pollution, has highlighted the inability and unwillingness the States had to protect its citizens. Thus, it is to underline that changing Climate and nature l...
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Telogen effluvium is one of the most common forms of diffuse, non‐scarring hair loss for which patients present for clinical evaluation. It is usually a reactive and reversible disorder. Identifying and correcting the underlying cause is the most important component in management, yet there is always a need for therapeutic options. This study aims...
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Background: Treatment of psoriasis results in alteration in clinical and histopathology findings with resultant inconclusive histopathology findings and a diagnostic dilemma in resource poor settings. Objective: To document the histopathology of clinically correlated psoriasis, compare with other studies and observe any differences in features. Met...
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Metabolomic profiling is an emerging field consisting of the measurement of metabolites in a biological system. Since metabolites can vary in relation to different stimuli, specific metabolic patterns can be closely related to a pathological process. In the dermatological setting, skin metabolomics can provide useful biomarkers for the diagnosis, p...
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Purpose of Review To review when to consider a diagnosis of cutaneous T-cell lymphoma (CTCL) in the inpatient setting and the diagnostic approach, as well as complications of disease and treatment that could lead to hospitalization. Recent Findings Cutaneous T-cell lymphomas (CTCLs) are a diverse group of non-Hodgkin lymphomas that are difficult t...
Preprint
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The evolution of behavior of dermatology patients has seen significantly accelerated change over the past decade, driven by surging availability and adoption of digital tools and platforms. Through our longitudinal analysis of this behavior within Tunisia over a 35-year time frame, we identify behavioral patterns across economic and cultural dimens...
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Introduction: Risankizumab has demonstrated efficacy and safety in phase 3 studies in patients with moderate to severe plaque psoriasis. This randomized clinical trial assessed the efficacy and safety of risankizumab in patients with moderate to severe plaque psoriasis in the Russian Federation. Methods: Patients with moderate to severe plaque p...
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OBJECTIVE: To perform a bibliometric analysis considering the thesis completion related to psoriasis, stored in digital repositories from universities in Mexico. MATERIALS AND METHODS: A systematized analysis of the digital repositories from Mexican institutions having thesis records on psoriasis during 1969-2020 was performed using Zotero referenc...
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Background: Genital warts are a common sexually transmitted disease (STD), and there is no method that completely prevents its recurrence. Recently, zinc has been used in the treatment of cutaneous warts. Nondestructive action, ease of use, and promising results with low chances of relapse were reflected in the treatment. These effects may arise f...
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Background: Subcutaneous (SC) methotrexate(MTX) is considered to be associated with a higher and predictable linear bioavailability as compared to oral MTX. Although various studies have reported SC MTX to be safe and effective in psoriasis, prospective head-to-head comparative trials on oral vs SC MTX are limited. Objective: To compare the effi...
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Immunosuppressive agents are essential for graft survival in solid‐organ transplant recipients (SOTRs), but they have substantial durable side effects, including a higher incidence of aggressive non‐melanoma skin cancers (NMSCs). Hitherto, only one class of immunosuppressants, mammalian target of rapamycin inhibitors (mTORi), may inhibit skin tumor...
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Dupilumab is a monoclonal antibody approved for the treatment of moderate‐to‐severe atopic dermatitis (AD) in patients aged ≥12years. Large, double‐blind, randomised, placebo‐controlled trials showed its efficacy and safety in adolescents. However, real‐life data are few. The aim of this monocentric retrospective observational study (December 2020‐...
Article
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There are several types of medical settings which use lasers. Dermatologists use lasers as it is non‐invasive with preferential cosmetic outcomes and finer wound healing. The types of lasers are relying on their wavelengths and delivery systems. Over time, by using several distinct devices and strategies, new lasers have been generated; as a conseq...
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Disseminated facial verruca plana is a chronic disorder that causes significant psychological distress. However, safe and effective treatment is lacking. This study aimed to explore the efficacy and safety of 35% glycolic acid for the treatment of disseminated facial verruca plana. A split‐face clinical trial was conducted to explore the efficacy a...
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Background Geriatric psoriasis, due to its unusual clinical manifestations and higher rates of systemic complications in this age group, is a challenging issue for dermatologists. Therefore, we aimed to provide an overview of the epidemiological, clinical and therapeutic consequences among patients aged over 60 years with psoriasis in a referral ce...
Article
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Resumen En dermatología es frecuente el uso de inmunosupresores e inmunomoduladores, algunos de los cuales pueden predisponer al desarrollo de enfermedad grave por SARS-CoV-2. Las nuevas terapias antivirales frente al SARS-CoV-2 han demostrado reducir la progresión a neumonía por COVID 19 grave en pacientes susceptibles. El pasado 23 de mayo, la Ag...
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Introduction: Primary focal hyperhidrosis (PFH) is a frequent condition which can seriously affect the quality of life. Intradermal injections of botulinum toxin A (BTA) is a safe temporary treatment. The objective was to assess the factors associated with the efficacy of the axillary injections of abobotulinumtoxinA in PFH. Materials and methods...
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Eight hot topics regarding the diagnosis and management of bacterial skin infections were selected and reviewed by five experts from different European countries, chosen based on their expertise in microbiology, infectious diseases, and dermatology. As noninfectious skin diseases/conditions such as atopic dermatitis can be complicated by infections...
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Purpose Scabies is a World Health Organization-defined neglected tropical disease and a growing public health issue worldwide. It is difficult to obtain reliable data on prevalence due to the lack of standardized tests. The aim of this study was to assess scabies online search behavior in Germany to identify local differences using Google search vo...
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Yu-qing Hu, Jian-zhong Zhang, Yan Zhao Department of Dermatology, Peking University People’s Hospital, Beijing, People’s Republic of ChinaCorrespondence: Yan Zhao, Department of Dermatology, Peking University People’s Hospital, No. 11 South Avenue, Xi Zhi Men Street, Xicheng District, Beijing, People’s Republic of China, Tel +86-10-88325472, Fax +8...
Article
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Honokiol is one of the natural extracts of Magnolia officinalis. It is a small molecule, lipophilic compound with extensive biological effects. It has been used in the treatment of multisystem diseases, including digestive diseases, endocrine diseases, nervous system diseases, and various tumors. This paper reviews the biological effects of honokio...
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Heng Zhang, Yifang Sun, Kun Li, Jianzhong Zhang, Xue Chen Department of Dermatology, Peking University People’s Hospital, Beijing, 100044, People’s Republic of ChinaCorrespondence: Xue Chen, Department of Dermatology, Peking University People’s Hospital, # 11. Xizhimen South St, Beijing, 100044, People’s Republic of China, Tel +86 10 88325472, Fax...
Article
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Atopic dermatitis (AD) and chronic urticaria (CU) are common skin diseases with an increasing prevalence and pathogenesis that are not fully understood. Emerging evidence suggests that oxidative stress plays a role in AD and CU. The aim of the single-center cross-sectional study was to compare markers of oxidative stress in 21 patients with AD, and...
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Psoriasis is one of the commonest inflammatory skin diseases determining a very high impact on patients’ quality of life and daily activities and relationships. Several biologic therapies have been approved through the years for the treatment of moderate‐to‐severe plaque psoriasis, and efficacy and safety profile have been analyzed in clinical tria...
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Background: Axillary osmidrosis(AO) and primary hyperhidrosis(PH) are common diseases, but there are still difficulties in treatment. Microwave therapy may become a new method. Objective: To evaluate long-time efficacy of patients with AO or PH treated by microwave. To discuss possible mechanism of microwave therapy by combining results of clini...
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La reproducción de las imágenes de los pacientes, en principio a través de los dibujos, se desarrolló en la medicina, desde sus inicios, con un criterio educativo. A través del tiempo, se la consideró una práctica habitual, sobre todo en algunas especialidades como la dermatología. Por ejemplo, en 1798, Sir Robert Willan contrató a varios talentoso...
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Psoriasis is a chronic dermatological disease with great impact on patients' quality of life (QoL). The main objective of this study was to assess the impact of secukinumab treatment on different patient‐reported outcomes (PROs) during a long‐term follow‐up in Spanish patients with moderate‐to‐severe psoriasis under real‐world conditions. Retrospec...
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Skin lesions are not uncommon in children, and most of them are benign. However, they can be a matter of concern. Although in most cases the diagnosis can be suspected based on clinical history and physical examination, in some cases clinical findings are nonspecific. High-frequency color Doppler US is a noninvasive technique that can play a releva...
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Public access to genetic information is increasing, and community dermatologists may progressively encounter patients interested in genetic testing for melanoma risk. Clarifying potential utility will help plan for this inevitability. We determined interest and uptake of genetic risk feedback based on melanocortin receptor gene (MC1R) variants, imm...
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Dear Editor, The COVID‑19 pandemic came with many lifestyle modifications such as social distancing, hand hygiene, regular usage of personal protective equipment (PPE.), including face masks, eye goggles, and gloves.[1] Changes in everyday routines, work cultures, and new lifestyle adaptations have unwanted sequelae like reduced physical activities...
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A aerial and Celestial based eponymous review in dermatology
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Background: Diagnostic algorithms may reduce noise and bias and improve interrater agreement of clinical decisions. In a practical sense, algorithms may serve as alternatives to specialist consultations or decision support in store-and-forward teledermatology. It is, however, unknown how dermatologists interact with algorithms based on questionnair...
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Since December 2019, a novel coronavirus, known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been rapidly spreading across the world, leading to the declared pandemic of COVID-19 [...]
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Objective: Telogen effluvium is one of the chronic diseases that affect the quality of life (QoL) in women. The study aimed to evaluate the RDW/MCV ratio and its correlation with ferritin in Telogen Effluvium patients and to reveal their potential role in the etiopathogenesis of Telogen effluvium. Material and Methods: We retrospectively evaluated...
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Introduction: Psoriasis significantly affects the patients’ quality of life, which often leads patients to seek online information about this disease. Objectives: To explore the habits of patients with psoriasis related to their use of SM and the internet to obtain information about their disease. Methods: 1,520 patients completed the survey and...
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Alopecia X (AX) is a non-inflammatory and non-pruritic skin disease characterized by progressive hair loss. The most commonly affected dogs are male Pomeranian, Chow-Chow and Poodles. Although there is a similarity with endocrinopathies that course with dermatological changes, AX does not bring systemic harm to affected dogs. The diagnosis is based...
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Introduction: Elderly population is vulnarable to experience a great number of dermatological diseases thanks to the intrinsic and extrinsic process of aging. Objectives: The aim of this study is to retrospectively investigate the prevalence of dermatological diseases in geriatric patients, their distribution by age and gender, and to provide a re...
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BACKGROUND: Some studies have assessed the incidence of heart defects in children suffering from Infantile Hemangioma to be treated with propranolol, showing a possible higher prevalence of cardiac abnormalities in this group of patients. METHODS: We retrospectively reviewed clinical charts of children with infantile haemangiomas referred to our D...
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Patients with severe COVID-19 both seroconvert earlier and develop higher concentrations of SARS- CoV-2-specific IgG than patients with mild symptoms. In this retrospective study we considered different categories of patients defined as "vulnerable" because affected by other pathologies, such as patients with genetic and cardiovascular diseases; pa...
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The introduction of novel, non-invasive techniques capable of improving the diagnostic accuracy and sensibility of both inflammatory and neoplastic cutaneous diseases has always been one of the most practical objectives of dermatological research [...]