Science topic
Depression - Science topic
Depressive states usually of moderate intensity in contrast with major depression present in neurotic and psychotic disorders.
Questions related to Depression
Dear colleagues, Current Neuropharmacology (IF 4.8; Q1 WoS and Scopus) announces a Special issue on
Emotion (Dys)regulation: An integration of Pharmacological, Neurobiological, and Psychological Frameworks
Sub-topics are as follows:
Pharmacological aspects of emotion regulation
Neurotransmitters involved in emotion regulation
Pharmacological interventions in emotion dysregulation
Neurophysiology of emotion regulation
Peripheral and metabolic mechanisms of emotion regulation
Emotion dysregulation in clinical samples
Psychotherapeutic and educational practices to improve emotion regulation
Submission closes on 31st December, 2025
To submit, go to:
Hi all,
I'm currently doing my masterthesis and I'm a bit stuck. My thesis researches the link between self-esteem and social relationships and how anxiety and depression influence this relation (a moderation). However, I can't seem te find any research to back-up my moderation. My hypothesis is that there's a positive relation between self-esteem and social relationships, but with higher scores of anxiety/depression, the relation weakens.
I do find enough research that indicate that there's a positive relation between self-esteem and social relationships - and that this relation can variate with other factors, such as age, gender or ethnicity. Just not anything about anxiety or depression.
What I also find are direct links between anxiety and self-esteem, anxiety and social relationships, depression and self-esteem, and depression and social relationships. Which all indicates that there's a negative relation between the variables.
So, my question is: how can I best justify my moderation?
Thanks in advance!
I´ve been reading some articles on bipolar disorder and it seems to be defined by the extreme shift between manic an depressive moods. However I don´t understand how that shift happens. Does it need a trigger to happen?
La Ansiedad y depresión son un problema de salud mental y los universitar
Liu Zhaosheng. 2003. Triassic and Jurassic sporopollen assemblage from the Kuqa Depression，Tarim Basin of Xinjiang，NW China. Palaeontologia Sinica， New Series A，no. 14（Whole no. 190）. Beijing：Science Press. 1‒244（in Chinese with English abstract）[刘兆生. 2003. 塔里木盆地库车凹陷三叠 纪和侏罗纪孢粉组合. 中国古生物志，总号第 190 册，新甲种第 14 号. 北京：科学出版社. 1‒244]
Zhang Shiben，Huang Zhibin，Zhu Huaicheng et al.. 2004. Phanerozoic subsurface stratigraphy of the Tarim Basin. Beijing：Petroleum Industry Press. xviii + 300 pp （in Chinese）[张师本，黄智斌，朱怀诚等. 2004. 塔里木盆地覆盖区显生宙地层. 北京：石油工业出版社. 1‒300]
Condition: "particular mode of being of a person or thing" / "a requisite or prerequisite, a stipulation," / "state; behavior; social status"
Symptom: "a departure from normal function or form as an expression or evidence of a disease," / "a happening, accident, disease," / "to befall, happen; coincide, fall together,"
It's becoming very apparent that mental health labels and loose terms of diagnosis are starting to cost countries a fortune.
I wanted to ask about depression because in the UK, some people get told they have depression as a condition. That diagnosis on its own can gain extra financial benefits and medical support.
When it is labelled alongside other things, it seems to convert into a symptom. Which I would imagine meant it is WORSE that depression. It's depression, plus some.
However, if it is "just" a symptom, it doesn't have any financial weight, or it is extremely hard to get the right support, because other symptoms start leading professionals into focusing on groups of symptoms which are faster than ever turning into conditions/ing.
Depression used to be called meloncholia. After a guy won a nobel prize in conditioning, the world had two massive wars within years. Then it was labelled "the Great Depression"
Depression is a transitional position. It feels like it is actually impossible to be depressed as a condition. If you are long term depressed, you must surely have other symptoms and conditions causing the depression to last? Or you must have not acknowledged something about yourself that needs processing properly?
I can think of no person who is just "depressed" without a story of why they feel that way, or where its cause is from." It feels like a bad therapist to just leave people with the label "depression". Is it not medically a term for "unfinished business"?
And strange that it can provide extra financial benefits, especially when people with more serious diagnosis struggle to get that same help and support.
What is so special about depression that it can be used as condition and symptom?
It feels like a loop hole created on purpose to trap poor people and or to make a bad therapist look good.
I need the Tunisian version of the Children’s Depression Inventory (CDI) for my master dissertation can anyone help please?
What happens to all the overworked people in academia?
Wellbeing and School Curricula
Why isn't psychological well-being (PWB) a core component of secondary school curricula?
I'm very curious to hear input from educators and policy makers on the above issue. Or from anyone reading this.
Is it because:
1) Secondary school curricula are traditionally focused more on intellectual growth than emotional growth. Parents are regarded as the source of education on emotional growth.
2) Educators and policy makers are not aware of the increase in rates of depression among teenagers globally.
3) Educators and policy makers are not focused on student depression / anxiety as they don't think it affects academic performance.
4) A lack of data on the impact of student wellbeing on student performance, resulting in skepticism that changes in curricula may have an impact on student wellbeing.
5) A different reason?
Depressed? Addiction? Mindfulness?
AI plays a crucial role in researching neurobiological factors associated with depression by analyzing vast amounts of data, identifying patterns, and assisting in the interpretation of complex biological information. Machine learning algorithms can analyze neuroimaging data, genetic information, and other biomarkers to identify potential indicators of depression. Additionally, AI models contribute to the development of personalized treatment approaches by considering individual variations in neurobiology, ultimately advancing our understanding and treatment of depression.
Who conducted the research of Women's Mental Health: Depression and Anxiety by Robynn Zender and Ellen Olshansky?
SO WHAT ARE THE JOBS WITH HIGHEST SUICIDE RATES?
1. Medical Doctors
2. Dentists
3. Police Officers
4. Veterinarians
5. Financial Services
6. Real Estate Agents
7. Electricians
8. Lawyers
9. Farmers
10. Pharmacists
Each year in the U.S., roughly 300 - 400 physicians die by suicide;
- In the U.S., suicide deaths are 250 - 400% higher among female physicians when compared to females in other professions;
- In the general population, males complete suicide four times more often than females. However, female physicians have a rate equal to male physicians;
- Medical students have rates of depression 15 to 30% higher than the general population. Depression is a major risk factor in physician suicide. Other factors include bipolar disorder and alcohol and substance abuse;
- Women physicians have a higher rate of major depression than age-matched women with doctorate degrees;
- Contributing to the higher suicide rate among physicians is their higher completion to attempt ratio, which may result from greater knowledge of lethality of drugs and easy access to means.
- https://www.acep.org/life-as-a-physician/wellness/wellness/wellness-week-articles/physician-suicide
- In the United States of America, an estimated 300 to 400 doctors die by suicide each year, a rate of 28 to 40 per 100,000 or more than double that of general population.
- https://en.wikipedia.org/wiki/Suicide_among_doctors#:~:text=The%20suicide%20mortality%20rate%20is,men%20versus%20the%20general%20population.
.
Dementia affects several millions of people across the world. There are various types of dementia and Alzheimer’s disease is the most common type. This disease that is yet to have a cure affects several millions of families in several different ways.
Dementia is a global crisis, perhaps we can call it the dementia pandemic! Dementia is everyone's problem and as a result, we must take the responsibility to look after ourselves. One of the easiest ways to support people living with dementia and their caregivers is to be aware of this disease and by so doing we probably can become a little bit more compassionate and dementia-friendly.
Most people living with dementia receive care from their immediate family members or friends and neighbours. This makes informal caregivers become isolated. They become what we call the invisible patients. Most people who provide informal dementia care are female caregivers mainly spouses, female adult children, family members, friends, and neighbours.
Dementia caregivers suffer equally as they are mostly available to provide the required care for their family members who are living with dementia. Informal caregivers suffer from several conditions such as physical and psychological challenges,
loss of job/livelihoods = financial problems, and loss of social life such as their hobbies. Among other challenges, informal caregivers suffer from stress, anxiety, and depression.
How dementia-friendly are you and how dementia-friendly are your localities?
A question that will debate and controversy...
Anxiety and Depression are only subjects of Psychiatry and Psychology?
What do you think Dear colleagues?
Suicide and Death Penalty, fatal and tragic acts, leave no one indifferent. These touch on the sacredness of life and therefore on the deepest convictions and beliefs. Philosophical reflection has been prolific on the subject dealing with the rationality and morality of and Death Penalty. The question also covers a societal component in relation to the debate on the "right to die within dignity"
All contributions on the topic are welcome.
Picture: Staged seppuku with ritual attire and kaishaku, 1897 https://en.wikipedia.org/wiki/Seppuku
There are several methods to consider the imperfection of the structure like the eigenvalue buckling mode, nonlinear buckling mode and weld depressions. But how to define imperfection as an equation in Abaqus software?
corona pandemic is worldwide issue and during the lockdown period people are getting depressed. so let all discuss their way of handling stress
Where could you find Numbers and Reports focus on Depression?
Dear research community,
In order to make the best with a focus on Depression, I tried to be aware about the different resources around Mental Health disorders.
I would like to know about updated reports in this issue not only in Europe but also if there is some other oficial reports or web observatories of this topic.
Thanks in advance.
What is the appropriate way to report the relationships among three interrelated variables in an observational study using GLM or mediation models?
Variables: Depression, Neuroticism, Mindfulness
Regression models - All of the relationships are statistically significant and passed assumption checks.
Mindfulness predicts Depression: R2 = .247, unstandardized coefficient = -5.32
Mindfulness predicts Neuroticism: R2 = .503, unstandardized coefficient = -3.88
Neuroticism predicts Depression: R2 = .732, unstandardized coefficient = 1.02
Should I simply report all findings, starting with the "strongest" relationship, Neuroticism predicts Depression?
Multiple Regression models - All of the relationships are statistically significant and passed assumption checks. Is there a benefit to reporting these model results beyond what is gained from the above regression models?
Mediation models - All of the relationships are statistically significant. All Sobel test results are statistically significant.
See attached file with results of mediation models and Sobel tests. Would I report all models or only that Neuroticism mediates the role of Mindfulness on reducing Depression, and Depression mediates the role of Mindfulness on reducing Neuroticism?
I'd like to know if there are other measures of hopelessness. As far as I know, there is only the Beck's Hopelessness Scale.
High school physics does not have the best affective appeal - not reputation among general student population-possibly due to content emphasis. Affective aspects however are important in early to mid stages of education.
Torques, circular motion and coulomb fields are depressing topics to the scientifically inadept; even more modern physics topics and high esteem terms like "constructive superposition" of waves and related phenomena do not faire better.
One however has to keep in mind that the mission of k 12 is to build some conceptual& skillsets/deep understandings that the next generations of scientists should have. Appeal is quarabteed what ever the topic choice for the later.
So the compromise is hard-leading to current win-lose solutions.
Suggestions such as for incorporation of whole year curricula on exciting, high contemporary culture status topics like radioactivity, laser apps, Vacuum conductivity have been raised to be balanced with half year courses on scientific method-a facelifted version of mentioned depressing content with deenpasis on content to teach skills/conceptual areas but keep things attractive to general population are still to gain persuasive power to be adopted.
Depression duration varies by individuals and recurrent episodes can be observed. What are the determinants of duration?
What do you think are the factors that have depressed this generation?
Why do you think it's hard for them to open up to others when it comes to telling how they feel?
The deterioration of mental health is practically notorious in Generation Z.
There are many young people today who do not share their problems and decide to deal with them alone.
The truth is that there is more and more use of antidepressants, more assistance to psychological therapy and more self-reported expression of anxiety and sadness in these generations.
List of some of the things that some people tend to do when they feel bad : listen to music, take refuge in drugs, buy clothes, dye your hair, don't eat, insomnia, etc.
How should you properly handle the relationship between yourself and your teachers in a situation where your advisor does not give you any academic guidance while you are pursuing your master's degree and you have to worry about graduating all the time,
while your teacher also attacks you psychologically? I thought I was going to get depressed.
Do I need to request permission to use Beck Depression Inventory and Beck Anxiety Inventory or I can simply use them since they are available in the public domain. How I can decide that any given survey is in the public domain or not ?!
I have been searching about the preventive intervention for depression and found several interventions but they are mostly for adolescents, I am searching for preventive intervention that are specific for adults.
The scales scoring guide (https://www.childfirst.ucla.edu/wp-content/uploads/sites/163/2018/03/RCADSUsersGuide20150701.pdf) only applicable for children till 12th grade. If I wanted to use it for adults (for which it has been validated but scoring guide unavailable. ), how should I score it?
Alcohol is a central nervous system depressant
Anxiety is something which happened before any situation and Depression is that which happened after any situation. Up to what extent it is true?
Waiting your response. Do you agree with it?
I want to find the correlation coefficients between two signals and to plot the deference in values using matlab. I have two eeg.edf datasets with 20 electrodes each, of healthy and depressed subjects. I have to find the correlation coefficient between electrode Fp1 healthy and Fp1 depressed, F3 healthy and F3 depressed and so on..
Can anyone help me with the code? so far I used edfread to transform my datasets in timetable variables.
Thank you!
I am doing a research project on prolonged social media use and the mental well-being of college students. I want to compare time spent as well as gender to the results of the Beck Anxiety Inventory and the Beck Depression Inventory. How would I go about comparing these and what statistical test would I perform?
I have to run a pearson correlation analysis between HPA axis markers- cortisol , ACTH and inflammatory marker IL-6(analysed through ELISA) and Depression anxiety questionnaires which were recorded at baseline and post interventions. I also need check the data for normality before running the analysis. If someone can provide an appropriate suggestion.
Apologises I'm really confused and don't know how to do, appreciate any guidance you can give
Aim
1. To explore if anxiety is predicted by stress and treatment delay and whether this is moderated by Brief Cope strategies (Brief COPE) .
Design
1 continuous outcome variable – anxiety (let’s call this H)
2 continuous predictor variables (let’s call these D, S)
3 Continous Moderator - (lets call these BC - ef, bc pf and bc avoidant). These are inputted into SPSS as 3 separate variables as the questionnaire b-cope does NOT allow you to create a total score (by adding ef + pf + avoidant).
- D – delay
- S – Stress (measured by pss-10)
- BC pf - Brief Cope - 1 (consists of 4 questions with each questions represent a different factor)
- BC ef - Brief Cope – 2 (consists of 9 questions with each questions represent a different factor)
- BC avoidant - Brief Cope – 3 (consists of 4 questions which each questions represent a different factor)
To answer the aim I know i need to complete a hierarchial multiple regression but I don't know what to enter on what model or whether I need to do separate regressions and again what should be entered with what.
Q1. Can you please advise how my regression models would look as I can't work this out given my predictors, moderators and outcome variable listed below.
E.g. Model 1 ...
Model 2 ...
Q2. Do I need to look at interactions? If so which ones, how would this be put into SPSS ie in which models.
Possible Interaction examples ?
Stress x bc ef
Stress x bc pf
Stress x avoidant
Delay x bc ef
Delay x bc pf
Delay x avoidant
Q3. Do I need to run separate hierachial multiple regressions? If so can you please write how the model would look ie. Model 1 ..
Model 2...
To confirm I have completed only parametric tests. I have 1 group completing all predictor /moderators variables.
Depression is a mood disorder that involves a persistent feeling of sadness and loss of interest. What are the causes, effects and probable solutions to depression? Sharing is caring. Thanks!!!
Hello, I have a question related to the metabolism of Serotonin. I am studying its metabolism in case of stress and depression and I could not find out the relationship between serotonin and 5HIAA in this particular case. MAO-A (the enzyme which metabolizes the serotonin hormone) inhibition is usually the mechanism of a lot of anti deprdepressantgs, but I have found several articles where the concentration of 5HIAA was lowered in case of depression and also suggestive of a lower concentration of Serotonin itself. But it doesn't justify the mechanism of action of antidepressant drugs. so I am confused now and want an answer for the exact relation of Serotonin and 5HIAA.
If serotonin is metabolized in 5HIAA, then 5HIAA concentration increases and serotonin descreases, so as serotoni conc. decreases, depression will increase. Is it right or no?
Dear colleagues in the filed of psychology and similar disciplines,
Do you know some open call for cross-cultural project regarding post-COVID effects (or what is happening after the 2 years of pandemic) on various aspects of mental health (life satisfaction, stress, anxiety, optimism...), emotional status, interpersonal relationships, risky behavior, conspiracy theories and other beliefs, etc.?
Thank you.
I have been able to access the 10-item clinician-administered version but am interested in using the self-report form. I'm able to find articles that cite its use and those testing its viability but none that include the actual measure.
Would it harm if an MDD patient receives TMS sessions 6 days a week instead of 5?
On a different note, is it required for the patient to receive 5 sessions in a row, or a patient could have TMS sessions simply 5 days a week in any order. Thanking you in advance.
I just came across a really interesting point of view in a clinical manual by a leading author in clinical treatment in Spain, Miguel Ángel Vallejo. He claims, based on a study by Rude and Rehm (1991)*, that psychotherapy is most effective when it boosts already-existing capacities and skills, rather than when it focuses on ameliorating deficits. That seems to run counter to much of what I have seen before in psychotherapy; does this idea match your clinical experience, or do you have any additional bibliography that might support this claim Thanks a lot!
*The citation to this article is given as "Rude, S. S., & Rehm, L. P. (1990). Cognitive and behavioral predictors of response to treatments for depression. Clinical Psychology Review, 11, 493–514"; however, all I can find online is this other article, with a different name, although (apparently) similar content: https://psycnet.apa.org/record/1992-06180-001
I guess there must be some data collected regarding Covid and related to the field of psychology/psychiatry, considering its psychological impact. It might be gathered from the patients, family members or the society at large, either a public or private collection. Does anybody have any idea on how to access such data for research purposes?
Can you tell me "what are the different clinical stages of Mental Health among young boys. " Related to anxiety or depression...If so can you plz tell me those stages.
E. G
Stage 1
(a)
(b)
(C)
Stage(2)
Stage (3)
Stage (4)
Stage (5)
Stage(6)
----++++--
What are the characteristics of these stages?
How as a clinical practitioner do you define these characteristics.?
As said in the title, I'm looking for a journal related to my research Twitter Arabic Sentiment Analysis to Detect Depression Using Machine Learning
to publish it it's preferred to be Q1
please help me out.
What do you think are the most important psychological disorders associated with COVID-19?
Friends and colleagues that use psychological questionnaires to measure depressive symptoms: what is your preference between the PHQ-9 and the BDI-II?
why the score value in research gate depresses with weekly updated, sometime?
What are the pharmacological risks?
I am a Medical student working on a research concerning mental health on young people. I am looking for a scale with good properties for symptoms of depression and anxiety.
Since the questionnaire includes many other dimension, short version are particularly welcome!
Thanks in advance!
What are the factors that predispose patients to treatment-resistant depression?
What are the advances that predict antidepressant treatment response for depression?
Two articles about prediction of antidepressant treatment response by using artificial intelligence technology and machine learning algorithms:
- An electroencephalographic signature predicts antidepressant response in major depression (doi:10.1038/s41587-019-0397-3)
- Brain regulation of emotional conflict predicts antidepressant treatment response for depression (doi:10.1038/s41562-019-0732-1)
I am working on a paper on unemployment on psychological health of youth. Please in what order can input the following predictors variables using age as the control variable?
Perseverance
Irrational behaviour
Low self esteem
Depression and
Suicidal ideation
To understand the gut microbiome-brain axis
I have done EIS of SDC (Sm doped ceria) electrolyte from 550 to 750C. I observed the formation of a depressed semicircle. Also the diameter of semicircle decreases with increasing temperature with a decrease in resistance. What could be the possible reasons for formation of depressed semicircle? I am attaching the figure below.
how many of us undergo the Stress of being a researcher ? does it motivates only or it does Depresses at Times ?
please do write your views on it.
Best regards
Hey, all! I'm conducting research including a depression screening as one of our measures - the Centers for Epidemiological Studies Depression scale (CES-D). This tool has cutoff scores: ≥16 indicates clinically relevant symptoms and ≥27 indicates moderate to severe symptomology.
Our team is discussing how to disclose to participants if they had a positive score after our research concludes. We want to inform subjects of anything clinically relevant but not cause harm. How do you all handle this?
I do not know if this is a merely coincidence, but over the last number of years doing research, I have seen hundreds of Junior Researchers (either undergrad, master of PhD students) suffering from blood- and energy-suckers coordinators. Perhaps, this is a consequence of multiple factors (such as history of academic world and labor western culture). The fact is, as a Senior Researcher or Project Coordinator, what do you do to avoid or to alleviate mental illness amongst your students?
I need a stack of black and white .jpeg/.tiff/.jpg/.png images across time of either action potentials, neurons firing, or brain scans (comparing disease and normal brain, disease progression, etc.) that I can colorize and overlay for a project in a data visualization course. It wouldn't be published and only for submission to the instructor.
Something like this for action potentials ?
I'm doing a research with my team on Depression in India. We need a dataset of social media posts of Indian people. We want to do Sentiment Analysis on these posts and find out some insights which are India specific.
- We have tried Facebook(but its very hard to scrape data from it).
- We have tried Reddit(but got very less posts, also it doesn't tell the country)
- We looked twitter, but not fruitful.
It is possible that we can get data from the above three more efficiently, but do not know how?
If there is any forum related to depression, or mental health, it will also work.
We've also posted related question here:
- https://www.reddit.com/r/redditdev/comments/k2stws/getting_post_from_a_subreddit_only_from_users_of/
- https://www.reddit.com/r/datasets/comments/k2tx96/looking_for_social_media_posts_of_indian_people/
TL;DR: Looking for Indian dataset of social media posts of depresses/anxious people.
Dear colleagues
I'm interesting in vermiculture and vermicompost technology. However, I noticed that there were some negative impact effects of adding vermicompost to soil, and depressing growth rate of plants.
Is there any one noticed that or face problems with using vermicompost as organic fertilizers
Hi,
for a facial emotion recognition detection project, a friend asked me if I know where he could find a dataset with faces of depressed people.
I found this deep learning facial emotion recognition project:
based on theDexter Miranda’s photo project, "The Face We Make":
https://www.flickr.com/photos/thefacewemake/ utilisé dans ce projet deeplearning https://machinelearnings.co/facial-emotion-recognition-single-rule-1-0-deeplearning-c90c3c2be788
But, the photos are not specifically about "depressive faces" (more about emotions).
On Kaggle, I found a better dataset:
And the JAFFE dataset:
So, I would like to know if there are "scientific or psychological dataset" with photos of faces expressing different emotions with depressive symptoms?
Thanks,
Laurent Berry
I am interested in the literary origins of noir crime writing.
Can anyone recommend the very best, or 'must read', works on either the novelist Ernest Hemingway or the subject of the 'Forgotten Man' (that is American veterans of WWI and the mass unemployed of the Great Depression)?
Many Thanks!
Major Depressiove Disorder/ Depression/ Anxiety
Dear Colleauges,
What is the rationale for studying dopamine’s role in Major Depressive Disorder?
Major Depressive Disorder (depression) is a multifactorial, biologically and symptomatically heterogeneous condition. Amongst the numerous—and potentially equally valid—proposals concerning its aetiology (e.g., inflammation, genetics, stress-related mechanisms, etc.), one of the longest-standing ideas is the “monoamine hypothesis” stating that one or more dysfunctional monoamine systems are key contributors in the development of this psychiatric disorder. Historically, most of the research focus has been on the role of serotonin and noradrenalin. Although this might not be “The” biological explanation for depression, a dysfunctional monoamine system, dopamine system in particular, is likely to contribute to the emergence of the two “sine qua non” symptoms associated with depression: on one hand, depressed mood and reduced motivation/perseverance and on the other, anhedonia and loss of interest in what were previously pleasurable activities. There is growing interest in dopamine’s role in clinical depression, especially, in the way it works as a modulator of the brain’s reward systems. Furthermore, there is pre-clinical evidence that A10 dopaminergic neurons projecting from the midbrain ventral tegmental area to the nucleus accumbens and dorsolateral prefrontal cortical areas over several routes are associated with motivation, exploration, appetitive learning, reward-driven behaviours, and a depressive-like phenotype in experimental models of depression. The reward systems might also be implicated in aversive stimuli, a recent notion which needs to be further explored.
This Special Issue of Brain Sciences aims to bring together some of the current ideas on the function or dysfunction of dopamine and dopaminergic transmission in depression, by examining the most recent evidence from advanced clinical and experimental research. It will gather insights from well-acclaimed experts in the field towards answering the ultimate question: what is the true role of dopamine in Major Depression?
For more information on contributing to this Special Issue, please go to:
Thank You!
Dr. Màté D. Döbrössy
Guest Editor
Are feelings of emptiness commonly experienced even within non-clinical populations? If so, are these experiences less salient due to a lack of personal awareness about the problem? Or, are people reluctant to disclose this feeling due to societal stigma?
In other words, is emptiness a major problem in modern society, and, if so, why is it so inconspicuous?
Why the number of secondary depressions on existing chromosomes varies?
As millions are getting depressed losing health and job and loniliness ,anew hope is begining to build up.really we need to this encouragement.we need all hygene ,distant physically to immune ourself from epidemic .this is new oxygen and new life really.so How can we fight depression and fear?lets hope that vwe recovered from deadly disease ,to get new life ,freedom and happiness.
Evidence is accumulating that glutamate abnormalities may also play a role in depression. But how does the glutamate level change? In chronic mild unexpected stress models, the glutamate level is decreased. But in the early stress, the glutamate level is increased. In my opinion, the early stress results in the increased glutamate, which leads to glutamate-mediated toxicity and damage the neurons. Later, the loss of neurons lead to decreased glutamate.
Anyone has a pdf form of Children''s Depression Inventory 2 (CDI2)
Hello everyone! I am researching the molecular mechanisms which drive depression in the context of gut microbiota. From what I know, depression's pathogenesis primarily relies on Tryptophan metabolism. On one hand, the pathway is perturbed to the kynurenic pathway which leads to the formation of kynurenic metabolites (KYNA, QA, XA, etc). These kynurenic metabolites exert neurotoxic effects which ultimately drive depression phenotypes. They are also able to affect the enteric nervous system, the gut millieu, and immune system which contribute to depression.
On the other hand, Tryptophan metabolism can also be driven towards serotonin synthesis. Inflammatory bowel disease and its likes (Crohn's disease, colitis) have been shown to have increased serotonin (evidenced by increased TPH expression) and decreased SERT expression. Serotonin has been shown to be pro-inflammatory and this supports the inflammatory theory of depression.
While these explanations do not completely contradict each other and that they may simultaneously contribute to depression, an "irony" still exist that one says a perturbation towards kynurenine while the other is towards serotonin. Either way, Tryptophan is consumed and surely leads towards an increased bias to one pathway (ie. increased serotogenic or increased kynurenic). Hence, do you know of any articles which settle this apparent contradiction? Or perhaps there is something I incorrectly understand?
Thank you!
Hi all,
I am doing a longitudinal study using depressive score as my DV. It is an observational study. No variables are manipulated. I have currently collected baseline (Time 1) and first follow-up (Time 2) data. I have a number of variables as predictors of the depressive score and I would like to identify what hypothesized variables collected at baseline would predict the Time 2 depressive score, and possibly be significant predictors for depressive scores at other time points in the future.
Do I
1) put predictors at baseline as IV, change score of depressive score as DV in the multiple regression model?
or
2) put predictors at baseline and baseline (Time 1) depressive score as IV, and Time 2 depressive score as DV in the multiple regression model?
I have actually tried both methods, it ended up that while using method 1, the predictors of change score are the same as those of Time 1 depressive score.
Whlie using method 2, no predictors (not even baseline depressive score) at baseline are significant predictors of Time 2 depressive score.
I wonder how I should have analyzed and interpreted the data. Thanks a lot!
Anna
In your personal experience,How do you manage your life and make a balance between work, family and other related sections!?:)
I would be thrilled to have your points!
After being affected with that viruse , most of the patients feel depressed and sad . How can we , psychologically, encourage them ?
please guide me about the sample size calculation for this study
I am trying to discern whether, in the brain (structure & function) of people with bipolar disorder/MDD/schizophrenia who experienced childhood trauma, there are:
1. already differences in children's brain structure & function that trauma further modifies and the person develops a mental illness OR (genetics first then trauma)
2. trauma changes the structure and function of the brain that the child's genetics further modifies and the person develops a mental illness (trauma first then genetics)
Has anyone researched this & if so, can you please share your findings or references you know of?
Hi Everyone,
I want to analyse how well two scales agree for detecting changes in wellbeing. I look at the Bland-Altman Method. One scale is a simple score from 0 - 10 for wellbeing. The other scale is the well established Beck’s Depression Inventory-II (goes from 0 - 63) . I wonder how to analyse the agreement?
Thanks!
Fred
I am a physician and visiting research scientist at yale and together with my coauthors have published several studies in the field of psychology through Network Modeling and related analyses using r packages like bootnet, qgraph, NetworkComparisonTest, etc. I thought it might be a good idea to discuss different subjects related to this field, in a group. I am also interested in collaboration with other teams working in the field. Let's share our ideas, questions and suggestions in this group.
I have a student conducting research on coping mechanisms used by males with partners suffering from Post Part Depression. It has been very difficult getting participants to complete the survey. Any suggestions on where this can best be posted to improve participation?
Already tried social media sites and groups focused on male issues with limited response.
With everyone having their own struggle and a different definition of being 'stressed'. Does problems of 23 years old smaller than that of 46 years?
I am currently working on a database and I have tried various methods of machine learning and deep learning, all leads to poor classification/prediction. However, this might show that the two groups have no significant difference. For example, the database I have is a collection of audio speech and their associated depression level. I am assuming that the culture of where I am from and the strong religious believe, prevented the society from going too deep into depression. However, I need to find some literature to back up this statement. But, it seems that there are no significant difference between the acoustics of depressed and non depressed. Can I write these poor results in a paper? Any tips?
Thank you
Hello, I am working with the Beck Depression Inventory and Beck Anxiety Inventory. I am trying to establish cut points for depressed/not depressed and anxious/not anxious. I know that I need to use an ROC curve to find the cut points, but I am not sure of the process to get there. Can anyone provide directions on going from survey questions/answers (I have 22 participants who have completed both surveys; no missing data) to establishing the ROC curve?
Thank you very much
It is believed that there are several depressed people of COVID-19 lockdown. How a psychologist could support them amid the lockdown?
I would like to enrol into a master's program at one of these universities and write my master's thesis on a topic involving the above three components.
Is there any physiological value or index that show us a stress or anxiety level? For example in an experimental reseach, when we want to find out computer games effect on stress, depression or anxiety, How can we detect these disorders level by using with physiological indicators?
Dear all
Hope you are all safe and healthy. We are doing a study on Phubbing and its association with depression, anxiety, and couple satisfaction. Phubbing is an under-researched area despite the increasing prevalence of problematic internet use and the associated mental health consequences. Since we need a large number of respondents, we are posting here and requesting you all to kindly spare a couple of minutes to go through it.
We assure that it will only take a few minutes to complete the questions.
We also encourage you to share the study.
Feel free to contact us for any doubts
Here is the link:
PS: It can be filled by singles too, as couple satisfaction is only a part of the study.
Best regards
Pooja
Karthick
Bigya
Most of the commentary about the current COVID-19 induced economic challenges use either the 2008 global financial crisis (GFC) or the 1929 Great Depression (https://www.bbc.com/news/business-52236936) as reference points. The reference points most relate to; 1) the severity of the economic challenges and; b) the time it will take to recover from the current challenge, in relation to either 1929 or 2008.
In the outlook for the recovery period, it assumed that the recovery will either be in the form of V shape or an L Shape compared to previous recovery shapes.
The questions are as follows:
- Are there parallels between either the 2008 GFC or the 1929 Great Depression and the COVID-19 induced economic challenges? Can we possibly draw any parallels?
- If there is, in what way are these the same and in what way are they different, except for the obvious and "well documented" drivers and causes.
- What shape do you think the recovery will take/assume? V or L?
- How long will the recovery take, either as measured in number of years, quarters or months? and Why?
For ease of reference, see some of the links below
NB: The significance of the BBC reference is the quote (s) attributed to the MD of the International Monetary Fund (IMF).
I am writing a research proposal on psychological aspects of IBD (anxiety/depression...) what should I use as my themes for my lit review?
HI,
this is Farhana, currently studying Bachelor of Science in Computer Science and Engineering in BRAC University in Bangladesh.
My thesis project is on "Depression and normal condition" and I wanna find a clean EEG data set about Depression and normal condition. is it possible for you to share your data set with me?
Thank you
Depression, also called major depressive disorder or clinical depression, is a mood disorder that causes a persistent feeling of sadness and loss of interest.
Have you ever struggle with depression? Please advise how depression can be overcome?
Thank you in advance for sharing your knowledge and experience.
We are in the middle of a crisis, in the quarantines. Irresponsible behavior has brought us to our current state. We did not learn any lessons learned from viruses that preceded and resembled the COVID-19 virus. Today's topic is not the reason that led us to this situation but commenting on the measures we have taken. The study of (Bishwajit et al., 2017) examined the effects of physical activity on depression. Their study had a representative number of middle- and older-aged subjects (7204). They concluded that a lower frequency of vigorous physical activity was significantly associated with higher rates of depression diagnosed. Depression symptoms and physical inactivity are factors that are closely correlated with obesity (Garimella et al., 2016). The elderly population has a prevalence of anxiety and depression around 10 and 12 %, these findings are caused as a consequence of different factors. Health-related quality of life and physical function play an important role in depression and anxiety (Sousa et al., 2017). The logical conclusion is that physical activity can reduce the levels of depression. Many studies have addressed this topic. Throughout history, our race has evolved. From the beginning of the cognitive, through the agricultural and industrial revolution to the present, we can observe a trend of decline in physical activity. This trend was accompanied by the appearance of metabolic and chronic diseases. Chronic diseases are major killers in the modern era. Physical inactivity is the primary cause of most chronic diseases. (Booth et al., 2011). Physical activity primarily prevents, or delays, chronic diseases, implying that chronic disease need not be an inevitable outcome during life.
This brief introduction is just a small overview of the literature that has examined the topics of physical inactivity, depression, and chronic illnesses.
Because we are in quarantine, and our movement is restricted and in some environments disabled we face many difficulties. Speaking personally and listening to people from my surroundings, from a psychological point of view, quarantine has a rather negative impact on people. With this, the media and the internet, which is full of misinformation, make people panic.
The following questions are:
- Is quarantine an ethical solution?
- How will this inactivity affect people?
- How will inactivity affect obesity, chronic diseases, and ultimately, mortality?
Reference:
Bishwajit, G., O’Leary, D. P., Ghosh, S., Yaya, S., Shangfeng, T., & Feng, Z. (2017). Physical inactivity and self-reported depression among middle-and older-aged population in South Asia: World health survey. BMC geriatrics, 17(1), 100.
Booth, Frank W., Christian K. Roberts, and Matthew J. Laye. "Lack of exercise is a major cause of chronic diseases." Comprehensive Physiology 2, no. 2 (2011): 1143-1211.
Garimella, R. S., Sears, S. F., & Gehi, A. K. (2016). Depression and physical inactivity as confounding the effect of obesity on atrial fibrillation. The American journal of cardiology, 117(11), 1760-1764.
Sousa, R. D. D., Rodrigues, A. M., Gregório, M. J., Branco, J. D. C., Gouveia, M. J., Canhão, H., & Dias, S. S. (2017). Anxiety and depression in the Portuguese older adults: prevalence and associated factors. Frontiers in medicine, 4, 196.
Many people suffering from Typ one diabetes mellitus, could be identify as almost depressive as well.
Treatment of Bipolar Depression
During test of cycle_gate, we ask people to walk, then they pay attention to it and their way of walking is changed, also darkness can change it too.
but that is question, whether mental illness such as depression change the cycle_gate?that could help us to find therapies for these diseases.
Planning an intervention for infertile depressed and anxious people, for guidence purpose I want to go through those interventions if you know any. thank You
Is there a scale available free of cost and without copyright issues to evaluate self-efficacy for primary health workers ?
Similarly , are they scales available for evaluating change in social , health and economic outcome in depressed individuals located in low middle income countries ?
If the scales are not available , on constructing these scales can we develop a structured questionnaire assessing social , health and economic outcome in depressed individuals ? If so , what constructs should we undertake ?
Thank you
I am currently starting to write a literature review for my Doctoral Thesis. As I am writing, I am wondering about the acceptability of using only three books as references for a chapter (not the whole discussion) in my literature review.
The reason why I am doing because I found these three books are recent (2012, 2014, & 2015) and already consist of abundant information for the chapter.
I am writing a chapter about Depression and these three books has already given me information about 1) Types of Depression 2) Causes of Depression (from Biopsychosocial aspect) 3) Effect of Depression 4) Best Available Treatments 5) Prognosis of Depression. Furthermore, for me, these sub-chapters are already enough for one chapter only. Considering that there are still many to come.
Any critique or suggestions are welcome.
Thank you
I need to apply LiDAR for fault growth analysis project to study the presence of Strike-slip faults in strain linkage extensional regime.
I've seen at symposia that some people have success recruiting for research studies on subreddits like r/depression or r/anxiety. Does anyone have experience with this? I have an upcoming study where I think this recruitment method would be useful. Has anyone run into IRB issues with this recruitment method? If you've had success with this recruitment method, how did you go about making your posts?
I would like to write an academic essay on Depression among youth using Participatory Action Research and its applicability in our country but I dont have the idea how to make my ideas flow. Im starting to build an outline but it seems lacking and disastrous. Do u have any idea what are the essential information and data to include so that my paper will be clear and convincing? You can also include suggests readings that I could review. I highly appreciate any form of help.
Why Have Researchers so far failed to identify common GENE MUTATIONS that contribute to risk for MAJOR DEPRESSION?
