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Publications related to Cytology (10,000)
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Article
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Oral squamous cell carcinoma (OSCC), one of the most common types of cancers worldwide, is diagnosed mainly through tissue biopsy. However, owing to the tumor heterogeneity and other drawbacks, such as the invasiveness of the biopsy procedure and high cost and limited usefulness of longitudinal surveillance, there has been a focus on adopting more...
Article
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Purpose The aim of this study was to investigate the diagnostic efficacy of Acoustic Radiation Force Impulse (ARFI) for benign and malignant thyroid nodules in the presence and absence of non-papillary thyroid cancer (NPTC) and to determine the cut-off values of Shear Wave Velocity (SWV) for the highest diagnostic efficacy of Virtual Touch Quantifi...
Article
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Introduction Early diagnosis of cancer enhances treatment planning and improves prognosis. Many masses presenting to veterinary clinics are difficult to diagnose without using invasive, time-consuming, and costly tests. Our objective was to perform a preliminary proof-of-concept for the HT Vista device, a novel artificial intelligence-based thermal...
Article
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Anaplasma platys es una bacteria pleomórfica intracelular, gramnegativa obligada que afecta especialmente a las plaquetas del perro, transmitida principalmente por garrapatas. Patógeno de importancia relevante en medicina veterinaria y reconocido mundialmente por su potencial zoonótico. El objetivo del trabajo fue determinar por PCR a tiempo real l...
Article
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Endometritis is one of the most common disorders that negatively influence reproductive performance in dairy cows. The purpose of this study was to determine the predictive factors of the clinical cure of endometritis. A total of 700 Holstein dairy cows were examined for signs of clinical endometritis between 30 and 40 days in milk (the first exami...
Article
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PICO question In dogs with type I immune-mediated polyarthritis (IMPA), is sole treatment with other immunosuppressive agents as effective as treatment with corticosteroids at reducing clinical signs? Clinical bottom line Category of research question Treatment. Number and type of study designs reviews One pragmatic open-label randomised controlled...
Preprint
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Cell morphology is a fundamental feature used to evaluate patient specimens in pathological analysis. However, traditional cytopathology analysis of patient effusion samples is limited by low tumor cell abundance coupled with high background of non-malignant cells, restricting the ability for downstream molecular and functional analyses to identify...
Article
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Background The diagnostic process of patients with suspect pancreatic lesions is often lengthy and prone to repeated diagnostic procedures due to inconclusive results. Targeted Next-Generation Sequencing (NGS) performed on cytological material obtained with fine needle aspiration (FNA) or biliary duct brushing can speed up this process. Here, we st...
Article
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Background: Cerebrospinal fluid (CSF) is highly labile and delayed processing might alter results of analysis. Hypothesis/objectives: To determine the effects of time and addition of autologous serum on cytological evaluation of CSF. Animals: Ten client-owned adult horses requiring euthanasia. Methods: Prospective study. Serum and CSF were c...
Article
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Background To investigate the relationship between cyclin D2 (CCND2) and miR-206 expression in fine-needle aspiration cytology of thyroid carcinoma. Methods A total of 65 patients with thyroid carcinoma were selected as the subjects and 65 patients with benign thyroid nodules were in control group. The fine-needle aspiration cytology of thyroid no...
Article
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Purpose of Review Malignant pleural effusions (MPEs) are initially treated with thoracocentesis but usually reaccumulate. There is wide variation in the rate of recurrence. Those with rapid recurrence could benefit from early definitive treatment, whilst those with slower recurrences may not. Here, we discuss pleural fluid homeostasis, MPE pathophy...
Article
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Sarcomatoid urothelial carcinoma (SUC), a rare tumor of the urinary tract epithelium, exhibits a high degree of malignancy and therefore a poor prognosis. Due to the absence of specific clinical presentations and imaging findings, SUC of the renal pelvis masquerades as a renal abscess is frequently under-recognized or misdiagnosed as benign inflamm...
Preprint
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Background: The thyroid imaging and reporting data system (TIRADS) has been routinely used to report thyroid nodules since its introduction in 2017. Similarly, the Bethesda system is a well-validated method used to report the cytopathology of thyroid lesions for over a decade. The aim of this study was to investigate the correlations between these...
Article
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Canine chronic large granular lymphocyte (LGL) leukaemia is commonly characterised by moderate to marked lymphocytosis but not neutropaenia. In humans, LGL leukaemia is often associated with autoimmune disorders, including immune-mediated cytopaenias (mainly neutropaenia). This presentation is rare in dogs. The aim of this retrospective study was t...
Article
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Aim. To assess the reproducibility of cytological diagnoses in evaluating liquid cervical smears and immunocytochemical co-expression of p16/Ki-67 using manual and automatic methods. Materials and methods. Cytological smears prepared using the liquid cytology method on the Becton Dickinson device (SurePath technology) were studied. An immunocytoch...
Article
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Citation: Chowdhury, S.; Darragh, T.M.; Berry-Lawhorn, J.M.; Isaguliants, M.G.; Vonsky, M.S.; Hilton, J.F.; Lazar, A.A.; Palefsky, J.M. Abstract: The incidence of anal cancer is increasing, especially in high-risk groups, such as PLWH. HPV 16, a high-risk (HR) HPV genotype, is the most common genotype in anal high-grade squamous intraepithelial les...
Article
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Background. Cervical cancer is one of the most preventable malignancies in females. However, there is an increasing trend of disease incidence mainly due to the low specificity of routine screening tests. Aim. To assess the diagnostic value of standard tests for the diagnosis of cervix disorders based on the Digene test. Materials and methods. Th...
Article
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Introduction: The early identification of precursor lesions followed by appropriate treatment prevents development of cervical cancer and its consequences OBJECTIVE: The present study evaluated the influence of the Covid-19 pandemic on cervical cancer screening by comparing the quantity of tests to detect cervical cellular changes performed in Sao...
Article
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Background: Aberrant DNA methylation is an early event during tumorigenesis. In the present study, we aimed to construct a methylation diagnostic tool using urine sediment for the detection of urothelial bladder carcinoma, and improved the diagnostic performance of the model by incorporating single-nucleotide polymorphism (SNP) sites. Methods: A th...
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With the improvement of living standards, dietary interventions have become an appropriate approach to enhance memory and cognitive performance. The present study investigated the potential mechanisms of spatial memory and cognitive function improvement with the milk fat globule membrane (MFGM) intervention in mice. The Morris water maze experiment...
Article
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Objectives Globally, lung cancer is the leading cause of new cancer diagnosis and deaths. In spite of advancement in diagnostic modalities, lung cancer diagnosis is often delayed due to lack of bronchoscopy facility and techniques. In the present study, we have analyzed role of bronchoscopy in diagnosis of lung cancer with special emphasis on endob...
Article
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Digital environments like learning management systems can afford opportunities for students to engage in cognitive learning strategies including preparatory reading of advance organizers including lecture outlines and self-testing using ungraded quizzes. When timed appropriately, self-testing can afford distributed practice, an optimal approach to...
Article
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We previously reported anti-miR-328 therapy for dry eye disease (DED). Since decreased mucin secretion is a risk factor for DED, we aimed to explore whether anti-miR-328 affects mucin expression and goblet cells. MiR-328 was increased in goblet cells when they were under desiccating stress or treated with benzalkonium chloride (BAC), both of which...
Article
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Promoting neglected and underutilized crop species is a possible solution to deal with the complex challenges of global food security. Chayote is a Neglected and Underutilized Cucurbit Species (NUCuS), which is recognized as a fruit vegetable in Latin America and is widely grown in Asia and Africa. However, basic biological knowledge about the crop...
Preprint
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BACKGROUND To screen asymptomatic rural women for High Risk HPV DNA by CareHPV test and cytological screening by Papanicolaou (PAP) test. METHOD A total of Four hundred eighty (n=480) sexually active, non pregnant women in the age group of 20- 70 years were included in this study. Two cervical scrap samples were collected from enrolled eligible wom...
Article
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The informal group Caespitosa of Paspalum L. comprises 13–15 perennial species that are able to tolerate extreme climatic stresses, such as prolonged droughts, floods, and saltwater. Previous molecular phylogenetic studies have suggested that the Caespitosa might not be monophyletic, but they did not analyze a large enough sample of taxa for a mean...
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Objective: Follicular thyroid carcinoma (FTC) is less frequent but has a worse prognosis than papillary carcinoma. The available evidence on pre-operative characteristics of FTC is controversial. Our objective was to characterize the clinical, ultrasound and histopathological presentation of FTC patients treated Chile. Subjects and methods: Retr...
Article
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Introdução: Técnicas de microscopia são ferramentas dinâmicas para o estudo de citologia no ensino fundamental. Objetivo: Apresentar um relato sobre um relato sobre as experiências vivenciadas a partir da utilização de duas técnicas de microscopia. Métodos: Este estudo ocorreu no mês Maio de 2019, na Escola Municipal Mágylla Neto com alunos de duas...
Article
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We aim to describe the relationship between the immunohistochemical expression patterns of HPV E4 markers and the presence of HPV major capsid protein (L1) in cervical tissues obtained by biopsy of patients with abnormal liquid-based cytology (LBC) results, HR HPV infections, or clinically suspicious cervix. A novel HPV-encoded marker, SILgrade-E4...
Technical Report
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La rinite allergica (AR) è un problema sanitario globale che colpisce dal 5 al 35% della popo-lazione. L’infiammazione allergica è caratterizzata dall’attivazione di una rete cellulare com-plessa. La citologia nasale (NC) è uno strumento diagnostico molto utile per aiutare a sud-dividere la AR in endotipi infiammatori, cercando di caratterizzare la...
Article
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Background Fine needle aspiration cytology has been established as a minimally invasive, non-tumour seeding investigation of choice in the initial diagnostic pathway of parotid lesions. The purpose of this study was to compare the accuracy of fine needle aspiration cytology performed with and without ultrasound to determine whether one method shoul...
Article
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Struma ovarii is a rare taratoma that accounts for 0.5-1% of all ovarian tumors. It is sometimes difficult to differentiate struma ovarii from ovarian carcinoma. We encountered a case of struma ovarii that was suspected to be malignant due to the accumulation of massive ascites and an elevated CA125 level. It was successfully treated with laparosco...
Article
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Objectives The congenital embryonic tumor known as sacrococcygeal teratoma (SCT) affects 1 in 35.000–40.000 newborns and is more prevalent in female fetuses and neonates. A total of 25–50% of SCTs are diagnosed by an ultrasound (US) examination during the second trimester of pregnancy. Planning the manner of delivery, determining the risk of negati...
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Aim: Appropriate sample selection with a tumor fraction ≥20% without necrosis contamination is required for successful cancer genomic profiling (CGP). Rapid on-site evaluation (ROSE) is performed to assess adequate sampling. Method: This retrospective study included 54 patients who underwent CGP using liver tumor biopsy specimen with ROSE. Resu...
Chapter
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One of the most important elements in reducing cancer mortality rates is early identification. Oral cancer, for example, might be screened (much like squamous cell carcinoma.) by taking Papanicolaou test any dentist doctor. The only disadvantage is that manual processing of the vast amounts of data acquired by us is relatively expensive. CNN showed...
Article
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O carcinoma de células escamosas é considerado a segunda neoplasia mais comumente diagnosticada na cavidade oral de cães. O objetivo deste trabalho consiste em relatar um caso de carcinoma de células escamosas com localização em cavidade oral em um canino, dando ênfase em sua apresentação clínica e em seus aspectos citológicos e histopatológicos. F...
Article
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The Cattleya (Orchidaceae–Laeliinae subtribe) intergeneric hybrids, such as Brassolaeliocattleya (Blc.), have great ornamental value, due to their compact-size, with large and high color diversity of flowers. Artificial induction of polyploidy brings agronomic, ornamental and genetic benefits to plants. Polyploidization efficiency depends on factor...
Article
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In cytologic analysis of lung nodules, specimens classified as atypia cannot be definitively diagnosed as benign or malignant. Atypia patients are typically subject to additional procedures to obtain repeat samples, thus delaying diagnosis. We evaluate morphologic categories predictive of lung cancer in atypia patients. This retrospective study str...
Preprint
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Peritoneal metastasis (PM) is the most common form of distant metastasis and one of the leading causes of death in gastric cancer (GC). For locally advanced GC, clinical guidelines recommend peritoneal lavage cytology for intraoperative PM detection. Unfortunately, current peritoneal lavage cytology is limited by low sensitivity (<60%). Here we est...
Article
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Nascent crossover sites in C. elegans meiocytes can be cytologically detected using epitope-tagged versions of the pro-crossover protein COSA-1. In spermatocytes, differences exist between cytologically-detected and genetically-detected double crossover rates. Here, we examine nascent crossovers using both GFP- and OLLAS-tagged COSA-1. Similar to p...
Article
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PurposeThe utility of the Bethesda system for reporting thyroid cytopathology is debatable in determining the risk of malignancy in pediatric patients. Moreover, the upper age limit for defining the pediatric group has varied across different studies. The aim of this study is to compare the risk of malignancy (ROM) and risk of neoplasia (RON) acros...
Article
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Background: Several US risk stratification score systems (RSSs) have been developed to standardize a thyroid nodule risk of malignancy. It is still a matter of debate which RSS is the most reliable. The purpose of this study is to evaluate: (1) the concordance between the American College of Radiology TI-RADS (ACR TI-RADS) and fine needle aspirati...
Article
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Introduction Neutrophil plays a more and more important role in sepsis with paralysis of immunoregulation. Till now, there was no biomarker to identify and isolate the mature and immature neutrophils in sepsis patients. CD10 shows on mature neutrophils at the latest stages of its differentiation. Our study aimed to investigate whether CD10 was a va...
Article
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Most oncogenic human papilloma virus (HPV) genotypes stratify into two species, α-7 HPV and α-9 HPV. There are several studies that evaluate the relationship between HPV species and treatment outcomes and reports that HPV species is prognostic. The HPV genotyping was conducted using biopsy specimens which had been stored in these studies. We conduc...
Article
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Background Bladder cancer detection and follow-up is based on cystoscopy and/or cytology, but it remains imperfect and invasive. Current research focuses on diagnostic biomarkers that could improve bladder cancer detection and follow-up by discriminating patients at risk of aggressive cancer who need confirmatory TURBT (Transurethral Resection of B...
Article
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Two nondescript dogs were presented with a non-healing ulcer on the skin. On examination, multiple lumps were presented all over the body. Fine needle aspiration cytology was performed from the subcutaneous mass. Cytology revealed round tumor cells with vacuolated cytoplasm. The case was diagnosed as a canine cutaneous transmissible venereal tumor....
Article
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Background: Benign and malignant lesions of breast are one of the most common causes of palpable masses seen in women. Fine-needle aspiration cytology (FNAC) is the important modality of diagnosis of breast lumps. Previously, there were no uniform criteria for reporting breast FNAC. To overcome this problem, the newly designed system – Internationa...
Article
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Objective: Malignant pericardial effusion may affect almost 15 of the patients with underlying malignancies which deteriorates the prognosis. The prognostic significance of pericardial fluid cytology is under-represented in previous studies. Methods: A total of 73 patients with symptomatic pericardial effusion treated with pericardiocentesis wer...
Article
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Transbronchial needle aspiration (TBNA) is a sampling tool that has demonstrated a higher accuracy in the diagnosis of peripheral pulmonary lesions (PPL) compared to other techniques. However, there are no studies investigating the value of TBNA in defining the genotype of peripheral lung cancer. To evaluate the accuracy of TBNA in defining the mol...
Article
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To explore the ability of PAX1 methylation (PAX1m) to predict the pathological upgrade of cervical intraepithelial neoplasia (CIN) before cold knife conization (CKC). A total of 218 women that underwent colposcopy-directed biopsy (CDB) pathology for the confirmation of CIN2 and CIN3 between December 2020 to September 2021 were enrolled in this stud...
Article
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Encounter with ectopic salivary is a rarity in clinical practice. The ectopic salivary tissue harboring neoplastic pathology is infrequent phenomenon. The literature reports about are scarce. The present case report is unique for the reasons of diagnosis of pleomorphic adenoma in ectopic salivary tissue in the anterior triangle of the neck on fine...
Article
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Lingual thyroid is by far the most common presentation of ectopic thyroid. Though mostly asymptomatic it is associated with congenital hypothyroidism and importantly, absence of orthotopic thyroid making it the only functional thyroid tissue a patient has in many cases. It appears indistinguishable to orthotopic thyroid tissue on imaging, with avid...
Article
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Haematopoiesis is very complicated process of formation, development, and differentiation of bone marrow cells and its evaluation is very valuable diagnostic tool for the veterinary practitioner. So, the aim of study is to evaluate the healthy bone marrow cytology during first three months old. Ninety pups were involved throughout the study accordi...
Article
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Background: Corn Syrup is food syrup higher of carbohydrate, depending on grade. The study aimed to assess efficiency of Corn syrup as cytological fixative. Subjects and methods: This was laboratory based study, it has been conducted at Elrazi University included apparently 30 healthy students have been involved in this study. Results: Out of 30 sm...
Article
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Aim: In this study, it was aimed to investigate the malignancy rates of nondiagnostic (ND) thyroid fine-needle aspiration cytology (FNAC) material by evaluating either the result of the second FNAC or resection/biopsy materials.Method: Among the 1165 thyroid FNAC cases evaluated in the Pathology Department of Başakşehir Çam and Sakura City Hospital...
Article
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Postpartum diseases of uterus represent a foremost predicament in cattle farms affecting reproductive efficiency. Postpartum (PP) uterine diseases include metritis, endometritis and subclinical endometritis (SCE). Barring SCE, all other diseases project the clinical signs. Diagnosis of SCE at the early stage of PP has been a challenging task for ma...
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Cytology plays a fundamental role in the timely diagnosis and treatment of benign and malignant diseases. Reported rates of malignancy in effusions range from 15% to 50%. About 95% of them represent metastatic disease, consisting primarily of adenocarcinomas (70-77%). Mesothelial cells appear alone in most cases, but they may be in groups showing m...
Article
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Introduction To evaluate the density of conjunctival goblet cells (GCs) from in vivo confocal microscopy (IVCM) and impression cytology (IC) and mucin expression in ten glaucomatous patients treated with preservative-free latanoprost (Monoprost®) Methods Ten glaucomatous patients (10 eyes) were enrolled. Conjunctiva was examined clinically and morp...
Article
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The chromosome axis plays a crucial role in meiotic recombination. Here, we study the function of ASY1, the Arabidopsis homolog of the yeast chromosome axis associated component Hop1. Specifically, we characterized cross-over (CO) distribution in female and male meiosis by deep sequencing of the progeny of an allelic series of asy1 mutants. Combini...
Article
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Background: PAX1 methylation (PAX1m) and HPV viral load (VL) have been reported to detect cervical high-grade squamous intraepithelial lesions (HSIL), but the relationship between them is unclear. This study aimed to evaluate the correlation between HPV VL and PAX1m and its effectiveness in predicting cervical lesions. (2) Methods: A total of 476 w...
Article
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The process of conducting the educational process of “Histology, cytology and embryology” subject in a medical university during ongoing aggressive war includes psychological, legal and organizational components, where the focus for this fundamental theoretical subject should be made on high-quality digital tools, constant monitoring of feedback an...
Article
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Introduction: Fine-needle aspiration cytology (FNAC) of salivary gland swelling helps differentiate benign and malignant lesions, thereby allowing clinicians to plan proper management. Ultrasound-guided FNAC is more accurate than other methods of FNAC. It is simple and safe and lacks significant complications. It is also inexpensive and can be repe...
Chapter
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The genus Lepidagathis Willd. (Acanthaceae) with 148 species worldwide and it is represented by 29 species and nine varieties in India. Lepidagathis clavata Dalzell is listed as critically endangered species by IUCN. The mitotic chromosome number 2n=22 are reported for the first time and provide list of endemic species.
Chapter
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The genus Syzygium Gaertn. (Myrtaceae) comprises 1200 species distributed in tropics and subtropics. In India it is represented by 102 species. The present communication is an attempt to provide cytological review and endemic review of Syzygium species of India.
Chapter
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Eriocaulon L. is the largest and most widespread genus of family Eriocaulaceae, with about 482 species distributed widely in tropics and subtropics of the world. In India the genus represents about 110 species out of them 78 species are endemic to country. The present communication is an attempt to provide cytological review of Eriocaulon species o...
Article
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Background: Fine needle aspiration (FNA) is a reliable method in the initial assessment of thyroid nodules. This study evaluated the accuracy of fine needle aspiration cytology (FNAC) in cases of follicular neoplasm (FN) on the basis of histologic diagnosis, and reviewed the cytologic findings of FN according to the FNAC.Method: Among the 50 cases...
Article
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AimDuring choledochal cyst (CC) excision, the hepaticojejunostomy anastomosis (HJA) can be performed conventionally (CHJA) or with a Carrel patch (CPA). CPA can increase CHD diameter to 10–13 mm, preventing anastomotic stenosis and intrahepatic bile duct (IHBD) stones but may be at risk for malignant transformation.Methods The medical records of 83...
Article
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p>Nodular hidradenoma (NH) is an uncommon benign skin adnexal tumor that presents usually as solitary intradermal nodule. This study aims to discuss the various clinicopathological features of NH as it mimics other adnexal tumors, malignancies or metastasis particularly in uncommon sites. Twenty-four cases of histo-pathologically diagnosed NH durin...