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Publications related to Cytology (10,000)
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Among the hematopoietic neoplasms, leukemias are caused by myeloid or lymphoid cells in the bone marrow, which can either be acute with an unfavorable prognosis and mostly affect cats that tested positive for feline viral leukemia (FeLV) or chronic in older cats that have a poor prognosis. Leukemias have several classifications in which the differe...
Purpose
In Taiwan, the incidence of urothelial carcinoma of the upper urinary tract (UTUC) is high and intravesical recurrence is approximately 22%–47%. Thus, postoperative cystoscopy and urine cytology follow-up, which require experienced cytologists, are needed. The AIxURO system aligns with The Paris System (TPS) guidelines for reporting urinary...
Background
The efficacy of routine diagnostic laparoscopy with cytologic evaluation for gastroesophageal junction (GEJ) cancer is variable with no set guidelines. We hypothesize that findings from diagnostic laparoscopy in Siewert II and III GEJ tumors may differ, where routine diagnostic laparoscopy with washings yields low upstaging results in Si...
O Tumor Venéreo Transmissível (TVT) é uma neoplasia de células redondas de origem mesenquimal, altamente contagiosa e de caráter sexual, que acomete principalmente a genitália externa de cães, sendo mais frequente em machos e fêmeas não castrados. O objetivo deste estudo foi relatar o caso de uma cadela sem raça definida (SRD), de dois anos, atendi...
Aiming at addressing the issues of colour deviation and clarity reduction in digital pathological imaging systems caused by complex environmental interferences such as uneven slice thickness, sample jitter, and background noise, this paper proposes a multi-saliency-guided filtering fusion enhancement method that combines energy saliency and Gaussia...
The management of thyroid nodules is guided by the cytological classification provided by The Bethesda System for Reporting Thyroid Cytology. Notably, the biology of thyroid tumors in pediatric patients differs from that in adults, and there is limited research focused on pediatric cases. This study aimed to assess the effectiveness of the Bethesda...
O câncer de colo do útero é um problema de saúde pública, representando uma das principais causas de óbito em mulheres. O exame colpocitológico ou Papanicolaou constitui-se como importante ferramenta para o seu rastreamento e prevenção. A adequabilidade das amostras colhidas para a realização deste exame apresenta significativa relação com a detecç...
Bladder cancer (BC) currently ranks as the 9th most common cancer worldwide. It is characterized by a very high rate of recurrence and metastasis. Most cases of BC are of urothelial origin, and due to its ability to penetrate muscle tissue, it is divided into non-muscle-invasive BC (NMIBC) and muscle-invasive BC (MIBC). The current diagnosis of BC...
A neoplasia mamária ocorre frequentemente em cadelas mais velhas que não passaram pelo procedimento de castração, pois a presença de hormônios sexuais é considerada a principal causa. Esses tumores podem se apresentar de tamanho variável e os exames de citologia e histopatológico são os principais métodos diagnósticos utilizados. Esse trabalho tem...
Management of term pregnant dogs is a major and frequent clinical situation in small animal reproductive veterinary practices, and can be challenging. Whether a pregnancy is planned or unplanned, these cases require careful monitoring to prevent maternal distress and neonatal loss. Reproductive system evaluation of female dogs is useful for determi...
To investigate the diagnostic value of intraoperative cytology and rapid immunocytochemistry in primary central nervous system lymphoma. 254 cases of lymphoma and 82 cases of non-lymphoma were collected from 2010 to 2023. Frozen section(FS) was using alone in 44 cases during 2010–2014, FS and intraoperative cytology(IC) were using in 251 cases duri...
Objective: Radical surgery is the mainstay treatment for adenocarcinoma of the esophagogastric junction. The presence of microscopic residual tumor tissue after curative-intent surgery is associated with recurrence. This study compared the outcomes of patients with microscopic residual tumor (Residual+ group) and those without microscopic residual...
Background and Objective: The role of urine cytology during follow-up for low-grade (LG) non-muscle-invasive bladder cancer (NMIBC) is not well established, although cytology has low sensitivity in detecting LG recurrences. Our study aims to evaluate the impact of urine cytology as a complementary method to cystoscopy during follow-up for LG NMIBC....
La colecistitis en perros es una afección que a menudo no recibe la misma atención que a las enfermedades del parénquima hepático. Se han identificado dos rutas probables de infección: la vía ascendente desde el duodeno a través del conducto biliar común y/o la vía hematógena a través de la circulación enterohepática. Este trabajo describe un caso...
Background
Pilomatrixoma is an uncommon benign skin neoplasm originating from the hair follicle. Here, we report a rare case of giant and atypical proliferating pilomatrixoma affecting the eyelid.
Case presentation
A 47-year-old male presented with a solitary, giant mass on his left upper eyelid, which had recently shown progressive enlargement. T...
Differentiated thyroid carcinoma (DTC) is among the most prevalent endocrine cancers. The diagnosis of DTC has witnessed tremendous progress in terms of technological advancement and clinical operational guidelines. DTC diagnostics have evolved significantly over centuries, from early clinical examinations to modern molecular testing and imaging mo...
Chondromyxoid fibroma (CMF) is a rare, benign metaphyseal bone tumour characterised by a combination of chondroid, myxoid, and fibrous elements, which can affect any bone at any age, without a gender predilection. We report the case of CMF in a 47-year-old lady who presented with swelling of the left little finger to a tertiary care hospital at Kol...
Background: The increasing trend of cervical cancer in women in their 20s in Japan is largely attributable to the low rate of cervical cancer screening. This study aimed to assess the usefulness of human papillomavirus (HPV) self-sampling among 24-year-old Japanese women who had never previously been screened for cervical cancer during the coronavi...
Introduction: Thyroglossal duct cysts are common congenital neck anomalies in children, diagnosed through clinical assessment and ultrasound, and treated with the Sistrunk procedure to prevent complications like infection and malignancy. Case Description: We present a case of a 4-year-old male patient with a progressively enlarging neck mass for th...
Pulmonary carcinoids are uncommon malignant neoplasms, believed to derive from specialized neuroendocrine cells known as Kulchitsky cells. We evaluated a 69‐year‐old female presenting symptoms consistent with carcinoid syndrome, such as intermittent flushing and diarrhoea, along with complaints of shortness of breath and cough. Imaging revealed bil...
Managing thyroid nodules diagnosed cytologically as follicular neoplasms (FN) is challenging for patients and clinicians. Gene panel testing was recently introduced to determine the management strategy for FN; however, it is unavailable in Japan. In this study, we assessed FN management. This study included 2,144 FNs from 2,067 patients diagnosed b...
Background/aim:
To evaluate efficacy of the AIxURO system, a deep learning-based artificial intelligence (AI) tool, in enhancing the accuracy and reliability of urine cytology for diagnosing upper urinary tract cancers.
Materials and methods:
One hundred and eighty-five cytology samples of upper urine tract were collected and categorized accordi...
Introduction: We experienced a case of lung cancer in which arthrocentesis and radiation were effective in treating pain caused by malignant joint fluid. Case: An 80-year-old man was referred to our hospital because of right shoulder pain and difficulty in raising his right hand. Whole body computed tomography (CT) showed right lung tumor, multiple...
Background
Rapid on-site evaluation (ROSE) plays an important role during transbronchial sampling, providing an intraoperative cytopathologic evaluation. However, the shortage of cytopathologists limits its wide application. This study aims to develop a deep learning model to automatically analyze ROSE cytological images.
Methods
The hierarchical...
The use of CAR‐T is becoming more widespread in the treatment of haematological malignancies. In adults, secondary myelodysplastic syndromes (MDS) after CAR‐T have been described. However, there are currently no data on the risk of MDS following CAR‐T in children treated for acute lymphoblastic leukaemia (ALL). We studied all children treated with...
Introdução: Embora populares e geralmente eficazes, implantes mamários apresentam riscos como contratura capsular, rompimento, infecção, dores crônicas e, em casos raros, linfoma anaplásico de grandes células (BIA-ALCL). Fatores como inflamação crônica, contaminação bacteriana e predisposição genética podem contribuir para o seu desenvolvimento. Ob...
Apesar da dermatite alérgica causada por picada de ectoparasitas ser comum em animais domésticos criados em regiões de clima tropical e subtropical como o Brasil, não há relatos da causada por carrapatos em ovinos, provocando reações de hipersensibilidade e lesões dérmicas. Objetivou-se com esse relato descrever as manifestações clínicas, diagnósti...
Vaginal cytology is a simple technique that can be used to determine the stages of the estrus cycle, if there are pathological conditions of the reproductive tract, and the optimal time of mating. There have been many vaginal cytology studies and it's clinical applications have been reported in many species. There have been few reports, however, ab...
Papillary thyroid carcinoma is a differentiated thyroid cancer that arises from thyroid follicular epithelial cells. Sarcoidosis is a multisystem disease of unknown cause, characterized by monocytic infiltration and granuloma formation. We herein report a case of thyroid carcinoma complicated by sarcoidosis. When thyroid nodules and lymph node lesi...
Background
The combination of anti‐PD‐1 antibody serplulimab and chemotherapy is considered standard first‐line therapy for advanced esophageal squamous cell carcinoma (ESCC), but few later‐line treatments are available. Here we evaluated the therapeutic efficacy of the recombinant, humanized anti‐EGFR antibody HLX07 when used alone or together wit...
Squamous odontogenic tumor (SOT) is an exceedingly rare, benign epithelial odontogenic tumor showing squamous differentiation. It is composed of variably sized and shaped islands of cytologically bland, mature squamous epithelium within a fibrous stroma. In this report, we present a rare transformation of a squamous odontogenic tumor (SOT) of the m...
Identification and mechanism of Echinochloa crus-galli (L.) resistance to fenoxaprop-p-ethyl via physiological and anatomical differences between susceptible and resistant were investigated. The physiological and anatomical differences that were take into account were growth reduction, chlorophyll content reduction, lamina thickness, and xylem vess...
Automatic abnormal cervical cell detection provides cytopathologists with reliable evidence, rapiddiagnosis and reduced workload. However, this task is often prone to interference factors such as impurities,microorganisms, and neutrophils. The morphological diversity of abnormal cells also increasesthe complexity of detection. Unfortunately, existi...
BACKGROUND
High-risk non-muscle invasive bladder cancer (HR-NMIBC) patients require long-term surveillance with cystoscopies, cytology and upper tract imaging. Previously, we developed a genomic urine assay for surveillance of HR-NMIBC patients with high sensitivity and anticipatory value.
OBJECTIVE
We aimed to validate the performance of the assa...
Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) is a recently defined thyroid nodule category characterized by follicular architecture with papillary nuclear features but lacking classical papillary carcinoma features like papillae or psammoma bodies. The diagnosis of NIFTP is based on histological examination...
Thyroid tumors are uncommon in dogs, accounting for 1% to 4% of all canine tumors. The average age of affected animals ranges from 10 to 15 years. The aim of this study was to report the case of a 12-year-old mixed-breed female dog named Pirata, treated at the Veterinary Hospital of the University of Porto. During the physical examination, a nodule...
Background
Angiosarcoma, a very rare malignant tumor constituting 2%–4% of soft tissue sarcomas, manifest in diverse organs including skin, soft tissues, and bones. Histologically, angiosarcoma presents a wide range of morphologies, with epithelioid angiosarcoma (EAS) resemblance to carcinoma. The difficulty arises from the shared epithelial‐like m...
Background
For early detection and postoperative monitoring of upper tract urothelial carcinoma (UTUC), the traditional detection method was limited to its invasiveness and insufficient sensitivity. We aim to use urine tumour DNA (utDNA) for detecting minimal residual disease (MRD), early diagnosis and perioperative monitoring in UTUC.
Method
We p...
This study aims to analyze the clinical features, Radiological findings and diagnostic characteristics (tissue biopsy, flow cytometry and cerebrospinal fluid cytology) of primary central nervous system lymphoma (PCNSL). To improve the diagnosis of the disease.
A total of 19 patients with primary central nervous system lymphoma admitted to the Secon...
In this case, a 66-year-old female patient presented with the chief complaint of abdominal distention. Computed tomography and magnetic resonance imaging revealed no enlarged ovaries or obvious primary lesions; however, massive ascites and peritoneal disseminated nodules were observed. Ascites cytology revealed adenocarcinoma and immunohistochemica...
Background
Papillary thyroid carcinoma (PTC) with fibromatosis/fasciitis-like/desmoid-type stroma is a rare subtype of PTC,characterized by two distinct components: a classic papillary carcinoma component and a spindle cell proliferationresembling fibromatosis or nodular fasciitis. This stromal component adds a unique dimension to the tumor'spathol...
Objetivo: descrever e avaliar a opinião de estudantes de enfermagem sobre a utilização de um Serious Game (SG) como apoio para aprendizagem da técnica da coleta da citologia oncótica. Clique aqui para acessar o SG. Método: trata-se de um estudo descritivo exploratório. A população do estudo foi composta por 22 estudantes do curso de enfermagem, de...
Background
The objective of the following retrospective review was to perform a cost-effectiveness analysis of the use of molecular testing of indeterminate thyroid nodules compared to current management practices in Nova Scotia, Canada.
Methods
All cases of cytologically indeterminate thyroid nodules from January 1st, 2014 to December 31st, 2018...
Background: This study represents a follow-up analysis of the AnusGynecology (ANGY) study. Methods: This prospective, cross-sectional, single-center study recruited women for concomitant cervical and anal screening of HPV genotypes and cytology during a single appointment. All women with findings of either HPV or any type of dysplastic lesions on a...
2024 Cytopathology Education Seminar
“Case-based approach in Diagnostic FNA cytology”
- Lymph node FNA
A BSTRACT
Background
The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) aims to standardize the terminology and morphologic criteria associated with thyroid fine-needle aspiration cytology (FNAC) results while also providing corresponding risk assessments for malignancy. contributing to more consistent and standardized reporting of t...
Purpose
Leptomeningeal disease (LMD) is a severe complication of melanoma with a very poor prognosis. Despite improved treatment strategies and prolonged survival, the incidence of LMD has increased over the past decade. This real-world study aims to evaluate the efficacy and safety of intrathecal anti-PD-1 treatment in melanoma patients with LMD....
Background
Information regarding response rate to tigilanol tiglate for mast cell tumors in dogs is limited.
Objectives
Report the response rate and durability of tigilanol tiglate intratumoral treatment in dogs with mast cell tumors presented to veterinary oncologists.
Animals
One hundred forty‐nine dogs; 151 individual tumors.
Methods
Multicen...
This post hoc analysis explored the age-specific risk of cervical precancer in women infected with human papillomavirus (HPV), using data from a cohort of 7263 participants aged 21-71years undergoing cervical screening. We found a slightly varied prevalence of high-risk HPV (hrHPV) in different age, with highest in women under 30 years old (9.28% f...
Introduction Fine-needle aspiration cytology (FNAC) is an effective tool in the diagnostic work-up of patients with thyroid nodules. The aim of our study was to assess the diagnostic sensitivity of FNAC in thyroid cancer (TC) in Sweden by correlating the findings of preoperative FNAC with those obtained through final histology of the surgical speci...
Synovial sarcoma is a malignant mesenchymal tumour with an uncertain origin. It is most commonly seen in the extremities, particularly lower extremities. The diagnosis of synovial sarcoma can be challenging due to its morphological diversity. Histologically, it can be of three subtypes: Monophasic, Biphasic and Poorly differentiated. The transcript...
Background
Human papillomavirus (HPV)‐positive urinary tract carcinomas (UTCas) have distinct morphology and molecular features with potential treatment implications. Cytomorphologic analysis of these tumors on urine cytology specimens has not yet been reported. The authors evaluated the cytomorphologic findings of HPV‐positive UTCa on urine cytolo...
Context
Myoepithelial carcinoma (MECA) represents < 1% percent of salivary gland (SG) tumors with a mean age of 55 years. These tumors can arise de novo or in association with pre-existing pleomorphic Adenoma (PA). The cytologic features of MECA overlap with other SG neoplasms including the more common benign entities like PA and myoepithelioma and...
Recently, endoscopic ultrasound-guided tissue acquisition (EUS-TA) has been widely used to diagnose pancreatic ductal adenocarcinoma (PDAC). The histological examination of core tissues acquired using novel biopsy needles is the primary diagnostic approach for patients with PDAC. However, in patients with early-stage PDAC, such as Stages 0 and I, E...
Thyroid lesions are the most common endocrine diseases, occurring in usually all age groups, though accurate diagnosis still remains a challenge, as due to oncocytic potentials of Thyroid cells leads to like indeterminate or suspicious diagnosis. Long standing benign Thyroid lesion shows atypical presentation suspicious to malignancy. Now a days wi...
Oral Squamous Cell Carcinoma (OSCC) is a highly aggressive tumor with a poor prognosis and is most frequent histological neoplasm of head and neck cancers, and although it is localized in a region that is accessible to see and can be detected very early, this usually does not occur. The standard procedure for the diagnosis of oral cancer is based o...
Objective
This study aims to analyse high‐grade intraepithelial lesions (LIEHG) observed in a screening programme from 2010 to 2018 to more accurately describe them and formulate recommendations for best practices in the context of screening evolution following the introduction of an HPV test in primary cervical cancer screening in 2020.
Methods
T...
Introduction. Cytological diagnostics of thyroid diseases widely used in medical practice today. The standards and guidelines used in this examination ensure close cooperation between doctors of different specialties. Aim of research: To determine the methodological and organizational features of cytological examination of the thyroid gland, which...
A endometrite é uma das principais causas de infertilidade em éguas, sendo caracterizada pela inflamação do endométrio uterino, geralmente causada por bactérias como Streptococcus zooepidemicus e Escherichia coli ou por fungos. O objetivo deste estudo é revisar o manejo da endometrite crônica infecciosa e degenerativa em éguas, abordando os agentes...
This book introduces the revolutionary use of AI in the field of cervical cancer detection. The book explores how advanced computer algorithms can analyze medical images and patient data to enhance early detection and accurate diagnosis of cervical cancer. The book starts by providing a comprehensive overview of cervical cancer, its risk factors, a...
Background: Molecular testing can reduce the need for diagnostic thyroidectomy in cytologically indeterminate thyroid nodules. However, the health-related quality of life in patients managed with molecular testing is not well studied. Objective: The objective of this scoping review was to identify and analyze the health-related quality of life outc...