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Cosmetology - Science topic

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In psoriasis candle grease sign is a confirmatory sign, in this sign we are suppose to scratch the patches of psoriasis with a sharp edge like scale or knife and if scales are collected on that and they are having greasy nature then this sign will be positive. But in my patients scales are there but they are of dry nature scales are not greasy so should I consider this as candle grease sign positive or negative? Please guide?
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We have to see the skin (and not the scale) after scratching, for candle grease sign. After scratched, psoriatic scales fall off and if revealing a shiny candle-like surface, it should be considered as positive candle grease sign.
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Recently I have been working on a research project, and the project comprises formulating an ointment, but I am clueless about how to develop one, it would be a very noble help if someone could guide me through with that.
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Most of the ointment you want is a cream in cosmetics, usually composed of water and oil phases. The water phase is generally composed of water, colloids(or gel) and preservatives. The oil phase is typically an emulsifier that stabilizes the oil and then adds it depending on which phase your active ingredient belongs to. I have some stable cream body formulas on hand that I can provide you if you need them.
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Cosmetic products for the skin are normally emulsions to facilitate the penetration of the active ingredients. Hair growth solutions are normally water/alcohol solutions so that the product does not get the hair dirty. I'd like to know what do experts think about the possible penetration of actives on the scalp and if having wet scalp instead of dry before applying the product would be beneficial.
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Good Answer Federico Svarc
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For how many minutes 4% hydroquinone has to be applied in the evening and morning . Do we need to wash it off after sometimes?
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To say the truth from a dermatologist perspective 4% Hydroquinone is completely safe to use as topical application with adjunct of Sub screen creams. There is lot of practical evidence in African peoples who use 20% Hydroquinone in ethanol vehicle which develop zero percent ochronasis.
In nutshell to say 4% Hydroquinone is completely safe to use with appropriate sunscreen cream
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the choice for depeigmentation agents has been a challenge for many doctors and cosmetic companies.
has any one got any significant result with tranexamic acid?
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But whether it has any carcinogenic effect should be studied.
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Dear all scientists,
I am interested in the cosmetics that contain silica nanomaterial. I would like to analyse the characterisation of silica nanoforms found in the cosmetics by TEM, BET, DLS, XRD, UV-Vis and Nanosight. How to extract this nanomaterial from the cosmetics? Many thanks for any advice you would offer.
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Many thanks for your helpful information. I will try this.
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Hi, we are conducting a study at M D Anderson Cancer center addressing tobacco use in Cosmetology field students. We need articles for the same. Kindly let me know or provide me with links in case anyone here knows such studies or articles.Thank you in advance.
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Cigarette Smoking, Plastic Surgery, and Microsurgery. J reconstr Microsurg 1996; 12(7): 467-474, DOI: 10.1055/s-2007-1006620.
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The European union is hearing evidence on whether the lower the amount of topical vitamin A that may be used in a cosmetic.   Vitamin A is almost completely locked in the skin because there are no transport mechanisms to take it form tissues into the blood stream so topical vitamin A can never be absorbed into the  blood and poses no risks, even at high topical doses.  We need to show that higher levels of topical vitamin A reduce skin cancers, and make skin healthy.  High doses of oral vitamin A may well reduce alzheimers.  Vitamin A in conjunction with vitamin D keeps bones healthy.  I have used 50,000 i.u. per day for 22 years and my bones are better than average for 26 year old people on scanning.  We know already that certain leukemias respond to vitamin A.    I am collecting evidence and would appreciate as much feedback as possible.
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The problem that oral Vitamin A in high doses for a long time may have some hazards , since it is fat soluble , and not water soluble, so it could be deposited in the fat and liver for a long time, and theoretically if the person taking this large dose loose weight in a short period , a condition like vitamin A toxicity could prevail.
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Dermarolling is done for acne scars based on severity. What is the best time interval between two sessions of dermarolling, does active acne affect the result of dermaroller, when should one decide the number of times dermarolling is to be done?
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no result at all in my case
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What are the parameters that are required for the stability test other than storage period and pH? Should the parameters need to measure for every intervals of period?
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Have a look to the file I append
Regards
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(1)Assessing for ECM degradation ( antielastase, anticollagenase and anti hyaluronidase)
(2) Assessing anti-tyrosinase activity (hyperpigmentation)
Other?
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Thank you neeraj and ayub. I already have the article that you suggested. Currently, I am studying medicinal plants that have antiaging properties.Most of medicinal plants that I am studying have antioxidant potential...I am looking for other assessment methods from what i have listed for skin aging...
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Will shortly methylisothiazolinone/methylchloroisothiazolinone (MI/MCI) replace nickel as the most frequent patch test positive allergen? The epidemic of allergic contact dermatitis to MI/MCI is becoming a huge problem. In 2014 MI/MCI was the second most frequent allergen in our patch test unit with 13.3% positive tests, following 14.7%  positive tests to nickel, and preceding 6.3% positive tests to cobalt, 6.3% to fragrance mix I and 4.9% to chromium.  
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I believe it can be formulated safely using proper exposure-based risk assessment approach (1) particularly at acceptable low levels and in rinse-off products.  The increasing incidence of sensitization, in my view, is due to more and more widespread formulating in leave-on skin care products.  This includes products formulated without the chloro species, but with high levels of methylisothiazolinone (2).  Once sensitized in this way leaves one vulnerable to potential elicitation to lower concentrations - perhaps even in rinse-off applications.
1.  DOI: 10.1034/j.1600-0536.2000.042005251.x
2.  DOI: 10.1111/cod.12236
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It is known that hadrons can be divided in baryons (fermions of three quarks) and mesons (bosons of two quarks). The sum of their electric charge is always an integer number, e.g. the proton is one and the neutron is zero. What is the reason that we have not found one particle with, say, five or seven quarks?
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Daniel,
Above the temperature 200 MeV where the QCD--hadron phase transition occurs, the
hadrons are represented by their free quark subconstituents in rhermal equilibrium. They contribute more degrees of freedom than hadrons, forming a dense medium of quark matter. This phase transition occurs about 1 microsecond after Big Bang.
When the universe cools below the phase transition the  quarks become bound in hadronic matter; the separation between quarks in the nucleons increases, and the interaction between any two quarks in a nucleon cease to interact with quarks in neighbouring nucleons.
Your question is: just how unlikely is it that more than two or three quarks get bound in the same hadron at that brief moment of the QCD--hadron phase transition. To answer it one needs a good model, but I think it is reasonable that multi-quark hadrons would be rare. Perhaps such states exist in the interior of neutron stars or quark stars. A quark star is really what you are asking for.
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Natural or synthetic agents ?
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Avoid exposure to sunshine during the whole live .("... the skin does not forget any single photon..."), avoid drying skin, avoid using cosmetics, avoid smoking, avoid alcool, may be the most effective measures.
by Walter