Science topic
Coronavirus Infections - Science topic
Virus diseases caused by the CORONAVIRUS genus. Some specifics include transmissible enteritis of turkeys (ENTERITIS, TRANSMISSIBLE, OF TURKEYS); FELINE INFECTIOUS PERITONITIS; and transmissible gastroenteritis of swine (GASTROENTERITIS, TRANSMISSIBLE, OF SWINE).
Publications related to Coronavirus Infections (10,000)
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The COVID-19 pandemic, which began in 2019, remains one of the most dangerous infections that have had an impact to this day, but the dynamics of the disease has improved. This is due to the increase in the skills of doctors to fight this infection and the emergence of new and relatively mild strains of the disease.
One of coronaviruses back again to attack human, COVID-19 is highly similar to SARS-CoV Middle
East respiratory syndrome (MERS). This study aimed to find the possibility of changing/evolution of one of the
most virulent factor 'spike protein' which facilities the attachment of the virus to cell receptor(s), and in silico
designing and finding of B...
MERS-CoV (Middle East Respiratory Syndrome Coronavirus) is a severe respiratory illness that poses a significant threat to the Arabic community and has the potential for global spread. In this paper, we present deterministic and stochastic models to study the dynamics of MERS infection within hosts. For the purpose of describing the dynamics of MER...
Objective
To assess care transition quality and compare it with the clinical characteristics and continuity of care after hospital discharge of COVID-19 survivors.
Method
This is a descriptive, observational and cross-sectional study, carried out with 300 patients with COVID-19 who were discharged from a hospital in southern Brazil. The Care Trans...
Objective
To assess care transition quality and compare it with the clinical characteristics and continuity of care after hospital discharge of COVID-19 survivors.
Method
This is a descriptive, observational and cross-sectional study, carried out with 300 patients with COVID-19 who were discharged from a hospital in southern Brazil. The Care Trans...
Objective
To analyze the conceptions about COVID-19 among Brazilians who carry out commuting to work in clandestine mines located on the borders between Brazil, French Guiana and Suriname.
Method
This is qualitative research, from an analytical perspective, based on Social Representation Theory. Semi-structured, audio-recorded interviews were carr...
Objective
To analyze the conceptions about COVID-19 among Brazilians who carry out commuting to work in clandestine mines located on the borders between Brazil, French Guiana and Suriname.
Method
This is qualitative research, from an analytical perspective, based on Social Representation Theory. Semi-structured, audio-recorded interviews were carr...
Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 has caused millions of deaths since emerging in 2019. Innate immune antagonism by lethal CoVs such as SARS-CoV-2 is crucial for optimal replication and pathogenesis. The conserved nonstructural protein 15 (nsp15) endoribonuclease (EndoU) limits activation of double-stranded (ds)RNA-induced...
Repurposing vitamins as antiviral supporting agents is a rapid approach used to control emerging viral infections. Although there is considerable evidence supporting the use of vitamin supplementation in viral infections, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the specific role of each vitamin in defending against c...
Social isolation and control owing to coronavirus disease 2019 (COVID-19) are easing; however, concerns regarding new infectious diseases have not disappeared. Given epidemic experiences such as severe acute respiratory syndrome (SARS), the influenza pandemic, Middle East respiratory syndrome (MERS), and COVID-19, it is necessary to prepare for the...
The coronavirus’ (CoV) membrane (M) protein is the driving force during assembly, but this process remains poorly characterized. Previously, we described two motifs in the C-tail of the Middle East respiratory syndrome CoV (MERS-CoV) M protein involved in its endoplasmic reticulum (ER) exit (211DxE213) and trans-Golgi network (TGN) retention (199Kx...
Middle East respiratory syndrome coronavirus (MERS CoV) and severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) are RNA viruses from the Betacorona-virus family that cause serious respiratory illness in humans. One of the conserved non-structural proteins encoded for by the coronavirus family is non-structural protein 9 (nsp9). Nsp9 plays...
Background
Middle East respiratory syndrome coronavirus (MERS-CoV) was identified in humans in 2012. Since then, 2605 cases and 937 associated deaths have been reported globally. Camels are the natural host for MERS-CoV and camel to human transmission has been documented. The relationship between MERS-CoV shedding and presence of neutralizing antib...
Pada saat ini penerbangan merupakan salah satu moda transportrasi yang sudah banyak digunakan oleh masyarakat. Penerbangan tidaklah hanya sebuah moda transportasi biasa. Jasa pengangkutan udara merupakan jasa angkutan untuk orang maupun barang yang meliputi pengangkutan melalui jalur udara dan dapat digunakan untuk kepentingan privat atau pribadi m...
The coronavirus pandemic, besides generating health distress, influences the socioeconomic conditions of humankind. Every adolescent's lifestyle is affected by the virus. Healthy adolescents are not only key contributors to the forthcoming workforce but also a source of a country's human capital. The purpose of the article is to examine the efficac...
Viral enteric pathogens continuously burden intensive pig farming, causing gastrointestinal diseases of epidemic and endemic nature. The present study investigated two diarrhoea outbreaks on a large farrow-to-finish holding and subsequent circulation of outbreak-related enteric viruses. These viruses were characterised by whole genome sequencing, a...
An object of the present study was the development of liposomes loaded with the medicine Veklury® (remdesivir) stabilized by electrostatic adsorption of polysaccharide film formed from chitosans with different physicochemical characteristics and hyaluronic acid. The functionalization of the structures was achieved through the inclusion of an aptame...
Veterinarians and other professionals who interact with animals on a daily basis encounter an elevated risk of exposure to both known and as-yet-undiscovered microbial agents. Additionally, they are also exposed to physical, chemical, and environmental hazards. Enhancing occupational health and safety in this context carries significant global sign...
Post-pandemic MERS-CoV still presents risks
Darryl Falzarano, Research Scientist at the Vaccine and Infectious Disease Organization (VIDO), discusses potential solutions that are needed to tackle the coronavirus known as MERS-CoV. The COVID-19 pandemic rapidly brought new tools to protect us from coronaviruses – in the form of effective vaccines an...
A ten-language search found no economic analysis of symptomatic hemorrhagic fever importation for Crimean Congo (CCHF), Hantavirus (HV), Lassa (LV), Marburg (MARV), Middle East Respiratory Syndrome (MERS) or Nipah (NV) into the USA/EU/UK. This study used available literature to calculate the cost of importation of the six selected fevers with each...
Coronaviruses (CoVs, Coronaviridae) are a diverse group of viruses that infect mammals, birds, and fish. Seven CoVs infect humans, among which Severe Acute Respiratory Syndrome CoVs-1 and -2 and Middle East respiratory syndrome CoVs have shown how they can impact global health and the economy. Their spillover from bats-the natural reservoir-to huma...
Purpose
To analyze the perception of choristers who perform online rehearsals about symptoms, vocal disadvantages, adaptations in the singing routine and difficulties in rehearsals during social distancing due to the COVID-19 pandemic.
Method
Application of an online questionnaire investigating perceptions about the voice and singing routine and r...
Purpose
To analyze the perception of choristers who perform online rehearsals about symptoms, vocal disadvantages, adaptations in the singing routine and difficulties in rehearsals during social distancing due to the COVID-19 pandemic.
Method
Application of an online questionnaire investigating perceptions about the voice and singing routine and r...
Background
The global pandemics of severe acute respiratory syndrome, Middle East respiratory syndrome, and COVID-19 have caused unprecedented crises for public health. Coronaviruses are constantly evolving, and it is unknown which new coronavirus will emerge and when the next coronavirus will sweep across the world. Knowledge graphs are expected t...
Hospital-based transmission had a dominant role in Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome coronavirus (SARS-CoV) epidemics1,2, but large-scale studies of its role in the SARS-CoV-2 pandemic are lacking. Such transmission risks spreading the virus to the most vulnerable individuals and can have...
The Middle East respiratory syndrome coronavirus (MERS-CoV) was first isolated from a patient with acute pneumonia and renal failure in Saudi Arabia in 2012. By July 2023, MERS-CoV had resulted in 2605 human cases worldwide, causing a fatality rate of 36%, with 90.2% of cases being located in the Arabian Peninsula. The dromedary camel (Camelus drom...
The Covid-19 (coronavirus disease 2019) was caused by SARS-CoV-2, a highly pathogenic, novel zoonotic βcoronavirus. The infection was reported less than a decade after the outbreak of Middle East Respiratory Syndrome (MERS) in 2012, which was reported precisely a decade after SARS-CoV-1 infection, discovered in 2002; the three viruses being zoonoti...
Coronavirus disease (COVID-19) and its outcomes remain one of the most challenging problems today. COVID-19 in children could be asymptomatic, but can result in a fatal outcome; therefore, predictions of the disease severity are important. The goal was to investigate the human genetic factors that could be associated with COVID-19 severity in child...
Porcine epidemic diarrhea virus (PEDV) is a highly contagious coronavirus that induces diarrhea and death in neonatal piglets, resulting in substantial economic losses to the global swine industry. The mechanisms of PEDV infection and the roles of host factors are still under exploration. In this study, we used the ferroptosis pathway downstream ta...
Objective
To analyze the transition of care for post-hospitalization patients due to covid-19 in a hospital in northeastern Brazil.
Methods
Quantitative, cross-sectional, descriptive, and analytical study carried out between 2020 and 2021. The sample had 78 patients. Data collection took place by telephone with the support of a sociodemographic qu...
Objective
Map, in the scientific literature, the actions taken to promote the safety of patients with covid-19 in the hospital context.
Methods
This is a scoping review according to the Joanna Briggs Institute, using the Checklist Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews. In April 2022, searc...
Objective
Map, in the scientific literature, the actions taken to promote the safety of patients with covid-19 in the hospital context.
Methods
This is a scoping review according to the Joanna Briggs Institute, using the Checklist Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews. In April 2022, searc...
This article focuses on innovative development of Health Care Sector of the future in terms of modern challenges of the Covid-19 Coronavirus Infection in Ukraine Aims: To identify innovative healthcare delivery models that have been implemented in Ukraine as well as to evaluate their effectiveness in healthcare improvement of the access and deliver...
Human coronaviruses like MERS CoV are known to utilize dipeptidyl peptidase 4 (DPP4), apart from angiotensin-converting enzyme 2(ACE2) as a potential co-receptor for viral cell entry. DPP4, the ubiquitous membrane-bound aminopeptidase, is closely associated with elevation of disease severity in comorbidities. In SARS-CoV-2, there is inadequate evid...
Coronaviruses are positive-stranded RNA enveloped viruses. The helical nucleocapsid is surrounded by a lipid bilayer in which are anchored three viral proteins: the spike (S), membrane (M) and envelope (E) proteins. The M protein is the major component of the viral envelope and is believed to be its building block. The M protein of Middle East resp...
Multivalent antigen display is a fast-growing area of interest toward broadly protective vaccines. Current nanoparticle-based vaccine candidates demonstrate the ability to confer antibody-mediated immunity against divergent strains of notably mutable viruses. In coronaviruses, this work is predominantly aimed at targeting conserved epitopes of the...
Coronavirus spike proteins mediate receptor binding and membrane fusion, making them prime targets for neutralizing antibodies. In the cases of severe acute respiratory syndrome coronavirus, severe acute respiratory syndrome coronavirus 2 and Middle East respiratory syndrome coronavirus, spike proteins transition freely between open and closed conf...
COVID-19 or coronavirus disease 2019 is a pandemic contagion, leading to the death of many more people globally. In simpler terms, COVID-19 is a very contagious illness caused by the SARS-CoV-2 virus, which stands for severe acute respiratory syndrome coronavirus-2. The main aim of the present paper was to give an update about the incidence, mode o...
Aim Nanomedicine can play an important role in the various stages of prevention, diagnosis, treatment, vaccination, and research related to coronavirus disease 2019 (COVID-19). While nanomedicine is a powerful interdisciplinary means that offers various approaches in patient treatment, a number of factors should be critically studied to find approa...
Background
Economic relief programs are strategies designed to sustain societal welfare and population health during a regional or global scale infectious disease outbreak. While economic relief programmes are considered essential during a regional or global health crisis, there is no clear consensus in the literature about their health and non-hea...
Introduction: In recent decades, three significant coronaviruses have posed threats to public health: Severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East Respiratory Syndrome coronavirus (MERS-CoV), and in December 2019, a novel SARS-CoV-2 type coronavirus was reported in patients with viral pneumonia in Wuhan province. It was lat...
Representing more than 20% of all deaths occurring worldwide, infectious diseases remain one of the main factors in both human and animal morbidity and mortality. Approximately one-third of these deaths are attributable to viruses. Accordingly, over the past two decades, emerging and re-emerging viral agents, including the most recent SARS-CoV-2 an...
Objective
To analyze the transition of care for post-hospitalization patients due to covid-19 in a hospital in northeastern Brazil.
Methods
Quantitative, cross-sectional, descriptive, and analytical study carried out between 2020 and 2021. The sample had 78 patients. Data collection took place by telephone with the support of a sociodemographic qu...
Objective: This study aimed to conduct a bibliometric analysis of the global scientific output related to the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) between 2012 and 2022. Materials and Methods: The Web of Science database was searched for articles on MERS-CoV published between 2012 and 2022 for bibliometric analysis. The parameter...
The complete blood counting (CBC) parameters can, to a considerable extend, indicate health status of any patient. The blood parameters of 22 Coronavirus male pandemic victims are compared with their counterpart of male healthy individuals using unequal ANOVA biostatistics software. A significant drop (p≤0.002) in the number of WBC and an insignifi...
In the last 20 years, several viral epidemics, such as the
severe acute respiratory syndrome coronavirus (SARSCoV)
in 2002, and H1N1 influenza in 2009, have been
recorded. The Middle East respiratory syndrome coronavirus
(MERS-CoV) was first identified in Saudi Arabia in
2012. Recently, an epidemic with unexplained low respiratory
infections began...
To reduce the risk and effect of sudden incidents of public health that put people at risk across national and international boundaries, it is necessary to take both preventive and reactive measures. These measures are referred to as global health security. Discussions on health security in scientific gatherings have become more prevalent in recent...
Predictive Modeling and Control Strategies for the Transmission of Middle East Respiratory Syndrome Coronavirus. Math. Comput. Appl. 2023, 28, 98. Abstract: The Middle East respiratory syndrome coronavirus (MERS-CoV) is a highly infectious respiratory illness that poses a significant threat to public health. Understanding the transmission dynamics...
Background: With the emergence of new infectious diseases, infection control nursing (ICN) in hospitals has become increasingly significant. Consequently, research on ICN has been actively performed. We examined the knowledge structure and trends addressed in Korean ICN research. Methods: From 5 web-based Korean academic databases (DBpia, KISS, KMb...
Natural products such as domestic herbal drugs which are easily accessible and cost-effective can be used as a complementary treatment in mild and moderate COVID-19 cases. This study aimed to detect and describe the efficiency of phenolics detected in the galangal–cinnamon mixture in the inhibition of SARS-CoV-2’s different protein targets. The pot...
Emerging and re-emerging swine coronaviruses (CoVs), including porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), and swine acute diarrhea syndrome-CoV (SADS-CoV), cause severe diarrhea in neonatal piglets, and CoV infection is associated with significant economic losses for the swine industry worldwide. Reverse genetics syst...
Although the involvement of the ubiquitin-proteasome system (UPS) in several coronavirus-productive infections has been reported, whether the UPS is required for infectious bronchitis virus (IBV) and porcine epidemic diarrhea virus (PEDV) infections is unclear. In this study, the role of UPS in the IBV and PEDV life cycles was investigated. When th...
In the last decade and a half, the world has experienced outbreaks of a range of viruses such as COVID-19, H1N1, flu, Ebola, Zika virus, Middle East Respiratory Syndrome (MERS), measles, and West Nile virus, just to name a few. During these virus outbreaks, the usage and effectiveness of social media platforms increased significantly, as such platf...
A complete genome sequence of an avian coronavirus (AvCoV; 27,663 bp excluding 3′ poly(A) tail) was determined using nontargeted next-generation sequencing (NGS) of an oropharyngeal swab from a backyard chicken in a live bird market in Arusha, Tanzania. The open reading frames (ORFs) of the Tanzanian strain TZ/CA127/19 are organized as typical of g...
DC-SIGN is a C-type lectin expressed in myeloid cells such as immature dendritic cells and macrophages. Through glycan recognition in viral envelope glycoproteins, DC-SIGN has been shown to act as a receptor for a number of viral agents such as HIV, Ebola virus, SARS-CoV, and SARS-CoV-2. Using a system of Vesicular Stomatitis Virus pseudotyped with...
RNA viruses that undergo continuous evolution can cause infectious diseases, leading to considerable harm to public health, individual well-being, and economic growth. The virus transmission can be through human-to-human, animals to humans and insects or vectors. The viruses involved are Middle East respiratory syndrome coronavirus, human immunodef...
The coronaviruses (CoV) are ubiquitous pathogens found in wide variety of hosts that constantly pose a threat to human and animal health as a result of their enormous capacity to generate genetic changes. Constant monitoring of virus reservoirs can constitute an early-warning tool and control the spread and evolution of the virus. Coronaviruses are...
In a race to manage the COVID-19 pandemic, innovations in nanomedicine were crucial for vaccine development. This study compares nanotechnology research on coronaviruses (nanocovid) and nanotechnology research on influenza (nanoflu) to understand the unique characteristics and drivers of nanocovid research. The main differences between nanoflu and...
The β-coronavirus family, encompassing Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Severe Acute Respiratory Syndrome Coronavirus (SARS), and Middle East Respiratory Syndrome Coronavirus (MERS), has triggered pandemics within the last two decades. With the possibility of future pandemics, studying the coronavirus family members is...
Resumen
Introducción
1 de cada 5 casos de COVID-19 en México se presentó en trabajadores de la salud (TS) y la alta tasa de contagio provocó ausentismo por incapacidad temporal para el trabajo (ITT), así como la necesidad de establecer criterios para calificar la COVID-19 como enfermedad de trabajo (ET). No hay datos cuantitativos sobre la poblaci...
SARS-CoV-2, responsible for COVID-19, shares 79% and 50% of its identity with
SARS-CoV-1 and MERS-CoV, respectively. It uses the same main cell attachment and entry receptor as SARS-CoV-1, which is the ACE-2 receptor. However, key residues in the receptor-binding domain of its S-protein seem to give it a stronger affinity for the receptor and a bet...
In the last decade and a half, the world has experienced the outbreak of a range of viruses such as COVID-19, H1N1, flu, Ebola, Zika Virus, Middle East Respiratory Syndrome (MERS), Measles, and West Nile Virus, just to name a few. During these virus outbreaks, the usage and effectiveness of social media platforms increased significantly as such pla...
Background: The study of coronaviruses has grown significantly in recent years.
Middle East respiratory syndrome coronavirus (MERS-CoV) replicates in various cell types, and quick development has been made of assays for its growth and quantification. However, only a few viral isolates are now available for investigation with full characterization....
Since 2019, the world has been experiencing an outbreak of a novel beta-coronavirus, severe acute respiratory syndrome coronavirus (SARS-CoV)-2. The worldwide spread of this virus has been a severe challenge for public health, and the World Health Organization declared the outbreak a public health emergency of international concern. As of June 8, 2...
Background: Coronaviruses are a group of enveloped viruses with non-segmented, single-stranded, and positive-sense RNA genomes. These viruses can infect various important vertebrates such as pigs and chickens, as well as humans, causing respiratory diseases. Among them, there are two highly pathogenic coronaviruses that have resulted in global outb...
Announced on December 31, 2019, the novel coronavirus arising in Wuhan City, Hubei Province resulted in millions of cases and lives lost. Following intense tracking, coronavirus disease 2019 (COVID-19) was declared a pandemic by the World Health Organization (WHO) in 2020. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified...
Background: For diagnosing coronavirus disease 2019 (COVID-19), chest X-rays have emerged as a preferred modality because of their accessibility, affordability, and capability to identify various pathologies. Recent advances in deep learning algorithms have shown promise in distinguishing COVID-19 from other lung diseases. However, the use of diffe...
The fast and reliable diagnosis of COVID-19 is the foremost priority for promoting public health interventions. Therefore, double-antibody-based immunobiosensor chips were designed, constructed, and exploited for clinical diagnosis. Gold nanoparticles/tungsten oxide/carbon nanotubes (AuNPs/WO 3 /CNTs) were used as the active working sensor surface...
The ongoing threat of Middle East respiratory syndrome coronavirus (MERS-CoV) underscores the importance of developing effective anti-viral treatments. Current research was conducted to identify potential antiviral compounds from soft corals: Sinularia leptoclados, Sarcophyton ehrenbergi, Nephthea sp., Sarcophyton glaucum and Sarcophyton regu-lare....
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), continues to be one of the largest dangers to human health around the world. The need for effective antiviral and anti-inflammatory treatments is still extremely high as newly emerging variants threaten the efficacy of currently...
Recent studies have demonstrated that 3-O-methylfunicone (OMF), a fungal secondary metabolite from Talaromyces pinophilus belonging to the class of funicone-like compounds, has antiviral activity against canine coronaviruses (CCoV), which causes enteritis in dogs. Herein, we selected two additional funicone-like compounds named vermistatin (VER) an...