Science topic
Coronavirus - Science topic
A genus of the family CORONAVIRIDAE which causes respiratory or gastrointestinal disease in a variety of vertebrates.
Questions related to Coronavirus
Hello I'm an engineer new to structural biology and helping to develop a cloud docking tool for screening compounds, similar to Swissdock but with mass throughput and GPU optimizations.
Specifically we're helping researchers repurpose existing drugs against protein structures simulated from the novel coronavirus genome.
I'm planning to use GPU optimized AutoDock-GPU , which takes in <protein>.maps.fld
I know you can use autogrid to select the bounding box and generate the .maps.fld, but I've been unable to figure out the workflow.
Also for preliminary screening I want to search the whole protein without specifying a bounding box.
Is there a script for converting protein.pdb to .maps.fld?
Thanks!
The US Government Comparative Toxicogenomics database shows that Fluoride can inhibit Human immunity to viruses and pneumonia. Angiotensin I-Converting Enzyme (ACE), 2'-5'-Oligoadenylate Synthetase 1 (OAS1) and Intercellular Adhesion Molecule 1 (ICAM1) are included as susceptible epigenetic targets of the poison.
Wuhan is an area with high Fluoride exposure from atmospheric and groundwater pollution.
Are there more studies linking virus outbreaks or mutations with Fluoride?
This RG open question is linked to the previous about the dramatic evolution (partly unexplainable) of COVID19 in Northern Italy during wave 1.
The previous RG open question is reported below🔴 and resulted in a completely alternative model for the evolution🟨 of SARS-CoV/2 from pre-pandemic phase to pandemic phase.
In this specific RG question, the intention is to create an open discussion on the possible emergence of a violent outbreak of avian flu or similar in central Europe.
This concern arises from a qualitative model that links three events which in the past have always characterized the violent explosion of a bird flu or similar.
The model involves three steps.. https://www.researchgate.net/publication/367046404
---Coronavirus Epidemic/Pandemic;
---Conflict/War partly out of control;
---Pandemic avian flu or similar.
The ABSTRACT of the model can be consulted directly here.. https://www.researchgate.net/figure/46_fig2_367046404
This RG open question will serve to accumulate data both for and against this dire possibility.
Thanks to all the participants.
|--sv--|
🔴The novel Coronavirus in N. Italy, Lombardia 【 COVID19 / 2019nCoV / SARSCoV2 】 shows a fatality rate compatible with SARS-MERS. Why?? MAR.2020. -- https://www.researchgate.net/post/The-novel-Coronavirus-in-N-Italy-Lombardia-COVID19-2019nCoV-SARSCoV2-shows-a-fatality-rate-compatible-with-SARS-MERS-Why
🟨Link between the start of pandemic SARS-CoV/2 (COVID19) and the Huanan Seafood Wholesale Market in Wuhan (Hubei: China): the furin cleavage site of spike protein. FEB.2022. -- https://www.researchgate.net/publication/358443761
Has the SARS-CoV-2 (Covid-19) coronavirus pandemic caused a reduction or increase in remote online communication, business cooperation, co-operation, clustering, etc. between companies, businesses, between business entities, financial institutions, public institutions, local government, non-governmental organisations and other entities?
In the sectors of manufacturing companies, financial institutions, online technology companies, online shops, etc., which experienced strong sales increases during the pandemic, the scale of business cooperation between business entities may have increased significantly. In contrast, in service sectors subject to lockdowns, forced reduction or real temporary cessation of business activities, sectors in lockdown-induced crisis and recession, the scale of development of business cooperation between economic operators may have decreased significantly. During the SARS-CoV-2 (Covid-19) coronavirus pandemic, lockdowns imposed on selected service and commercial sectors of the economy were introduced in some countries, triggering an economic recession in mid-2020. In addition to this, international supply and procurement logistics chains were disrupted which further reduced the ability to produce certain types of goods and exacerbated the economic crisis. As a result, some operators decided to carry out recovery programmes and to increase the scale of their business using the Internet, including providing their services, offering products via the Internet, selling their product and service offerings online, improving e-logistics and remote Internet communication. Therefore, as a result of the downturn in the economy, the decline in economic activity, the scale of business cooperation in many businesses may have decreased. However, on the other hand, the scale of business and other cooperation conducted through remote Internet communication, the development of e-logistics, online payments and settlements, etc. may have increased.
In view of the above, I address the following question to the esteemed community of scientists and researchers:
Has the pandemic of the SARS-CoV-2 coronavirus (Covid-19) caused a decrease or increase in the scale of remote Internet communication, business cooperation, co-operation, clustering, etc. between companies, enterprises, between business entities, financial institutions, public institutions, local governments, non-governmental and other entities?
And what is your opinion on this topic?
What do you think about this subject?
Please respond,
I invite you all to discuss,
Thank you very much,
Warm regards,
Dariusz Prokopowicz
My specialty is quantum physics but because of the pandemium I was interested in physical methods applied to virology. Today's physics is at nanolevel manufacturing so I suppose it can solve problems with viruses too.
As far as I know to force the organism to produce antibodies one can introduce the capsid or the envelope of the virus in it. I wonder if the following method below is used to collect capsids of a virus.
Method: I know it is possible to remove the nucleus of a cell. So lets take a number of cells from a human and extract the nuclea. Then put a huge number of the viruses in a culture with the cells. The viruses will inject their the DNA (or RNA) in the cells thereby leaving their capsids outside. But the cell can not reproduce the virus because there is no nucleus. Now one can separate the human cells with the viruses's DNA from the capsids and use the capsids to create antibodies by directly injecting as a vaccine.
What was the misinformation effect of conspiracy speculations during COVID-19 pandemic?
Study showed, when only 4.6% of population believed coronavirus was of a natural origin, irrational, denying and hesitant health behavior spread widely across nation.
People around the world are now nervous and confused about 'Corona Virus' . What are the differences between corona virus induced fever/cold/cough and normal fever/cold/cough ?
The high tide of coronavirus (COVID-19) has hit us again and again! And there are likely to be more deadly hits in the future. Meanwhile, preparations have been made to prevent the attack of a more deadly virus called 'Disease X'.
There is no way to stop this deadly virus. In this time of deep crisis, I have come up with two great ways to prevent viral infections including proper treatment of viral infections that can save countless lives. These methods will be effective in multiple ways. They are able to inactivate the virus and block and prevent the virus from entering the body cells. And the vaccine and the medicine I made will heal the person infected by the virus. And they are not at all harmful to our body.
To know more please watch video. Thank you
Coronavirus vaccine.. What happens after the virus changes its configuration ? What will the live vaccine induce in our bodies? What will the immune response produce in our bodies ?
The global COVID-19 (coronavirus disease 2019) pandemic, which was caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in a significant loss of human life around the world. The SARS-CoV-2 has caused significant problems to medical systems and healthcare facilities due to its unexpected global expansion. Despite all of the efforts, developing effective treatments, diagnostic techniques, and vaccinations for this unique virus is a top priority and takes a long time. However, the foremost step in vaccine development is to identify possible antigens for a vaccine. The traditional method was time taking, but after the breakthrough technology of reverse vaccinology (RV) was introduced in 2000, it drastically lowers the time needed to detect antigens ranging from 5–15 years to 1–2 years. The different RV tools work based on machine learning (ML) and artificial intelligence (AI). Models based on AI and ML have shown promising solutions in accelerating the discovery and optimization of new antivirals or effective vaccine candidates. In the present scenario, AI has been extensively used for drug and vaccine research against SARS-COV-2 therapy discovery. This is more useful for the identification of potential existing drugs with inhibitory human coronavirus by using different datasets. The AI tools and computational approaches have led to speedy research and the development of a vaccine to fight against the coronavirus. Therefore, this paper suggests the role of artificial intelligence in the field of clinical trials of vaccines and clinical practices using different tools.
Source:
Economics of different countries is collapsed because of COVID-19. What you think? What will be the opportunities of funding at higher studies after this Pandemic? Please share your thoughts regarding this issue. Your valuable thoughts will be highly appreciated.
The production, processing, and import/export of food items has been reducing significantly, which may result in food security issues in future, if not managed now.
A large percent of of crude oil is consumed by transportation sector globally .
By referring to previous years statistics , more than 60 percent of worldwide oil consumption
belonged to transportation sector .
Corona virus pandemic mainly struck the travel and public transportation industry
in short term , that are part of transportation sector .
So the question may ensue the following questions :
- How many percent of oil consumption belonged to travel and public transportation industry ?
- How many percent the travel and public transportation industry is struck by pandemic in monetary term ?
- And how many percent of travel and public transportation industry costs is allocated to fuel (mostly crude oil products) consumption .
Can anyone introduce some references ?
How did the SARS-CoV-2 (Covid-19) coronavirus pandemic increase the level of digitization and Internetization of economic processes, increase the scale of remote communication carried out between business entities and public institutions, increase the level of digitization of the economy?
During the SARS-CoV-2 (Covid-19) coronavirus pandemic, the government, with the aim of slowing the development of coronavirus transmission and increasing the period of preparation time of health system institutions for the development of the epidemic nationwide, introduced mandatory national quarantines imposed on the public and lockdowns imposed on selected, mainly service sectors of the economy. Companies and businesses on which lockdowns were imposed were not allowed to conduct business under standard conditions and could only provide their services remotely via the Internet during lockdown periods. This issue affected many companies operating, among others, in the sectors of tourist services, hotels, catering, gyms and fitness clubs, physical stores and shopping centers, cultural services provided by museums, galleries, philharmonics, theaters, operas, cinemas, etc. In addition to this, restrictions on the scope of services provided also applied to certain segments of transportation services, domestic and international air transportation, the public transportation system and many other services. The ability to move business operations and services provided to the Internet proved to be a viable option for many companies to survive the recession and economic crisis caused by the quarantines and lockdowns introduced in 2020. Since April 2020, sales of various products and services carried out via the Internet have increased rapidly. A significant number of citizens who, prior to the pandemic, did not make purchases via the Internet were suddenly forced to do so, as it were, by the pandemic situation and through government-imposed restrictions. In some product ranges, such as electronics, consumer electronics and household appliances, sales made via the Internet increased turnover several times during the pandemic. Consequently, in some product ranges, the pandemic not only changed customers' buying habits but also significantly increased the profits of stores that switched to online sales and manufacturers of certain types of products, for which demand increased significantly during the pandemic. During the pandemic, many companies, especially in the SME sector, increased the scale of digitization and Internetization of business processes. The government, as part of various anti-crisis, anti-decession measures, offered targeted subsidies to SME companies to increase the level of business digitization and adapt to the new realities of business development with greater use of the Internet. The result was an increase in the scale of digitization and Internetization of the economy. The scale of development of e-commerce, e-business, e-banking, online and mobile banking, e-logistics, e-learning, e-government, remote work, online payments and settlements, etc. has increased. I described the processes and key determinants of the increase in the scale of digitization and Internetization of the economy in articles of my co-authorship, which I posted on my profile of this Research Gate portal after publication:
For those who are interested in this issue, please read the issues, determinants, factors of growth in the scale of digitization and Internetization of the economy, which I have described in my articles. I am currently writing a monograph on this topic and invite researchers and scientists who consider this issue of interest to join me in scientific cooperation. I ask for your comments and suggestions on other determinants and factors of growth in the scale of digitization and Internetization of the economy, which have not been covered above. I also ask for your conclusions, results of reflections, considerations on the current and prospective effects of the progressive process of digitization and Internetization of the economy. Important questions that can inspire reflection on this issue are the following:
- To what extent can the increasing scale of digitization and Internetization of the economy go in the next few years, and what will be the consequences?
- What positive and negative effects can be distinguished from the continuation of the process of increasing the scale of digitization and Internetization of the economy in the coming years?
- How did the pandemic of the SARS-CoV-2 coronavirus (Covid-19) increase the level of digitization and Internetization of economic processes, increase the scale of remote communication carried out between business entities and public institutions, increase the level of digitization of the economy?
And what is your opinion about it?
What do you think about this topic?
Please answer,
I invite everyone to join the discussion,
Thank you very much,
Warm regards,
Dariusz Prokopowicz
What was the pandemic and post-pandemic impact of the SARS-CoV-2 (Covid-19) coronavirus pandemic on globalisation processes?
Increase in the scale of international scientific cooperation on SARS-CoV-2 coronavirus research and analysis of Covid-19 disease development; use of analogous anti-pandemic security instruments; disrupted chains of international supply and supply logistics; analogous changes in trends in financial markets, including raw materials markets, other types of production factors and stock exchanges; increase in the scale of digitisation of remote communication and business processes; increase in the scale of digitisation of public offices and institutions; increase in the scale of e-commerce, e-banking, e-payments carried out via the Internet, e-logistics, remote working, e-learning, e-government, development of online and mobile banking; negative social and economic impacts; a decrease in demand for energy and other raw materials in 2020 and an increase in demand for raw materials from 2021 onwards; a decrease in economic activity in the service sectors affected by the lockdowns; the analogous use of soft monetary and fiscal policy instruments; the emergence of inflationary pressures; an increase in inflation; the emergence of opportunities to accelerate the processes of pro-climate transformation of the energy sector, but these opportunities have been used to varying degrees in different countries, resulting in different levels of energy and environmental security in different countries, etc. These are just some of the effects of the pandemic and post-pandemic impact of the SARS-CoV-2 (Covid-19) coronavirus on globalisation processes. I am conducting research on this issue. I have described the results of my research and key aspects of this problematic in an article which, when published, I posted on my profile of this Research Gate portal:
If you are conducting research in this area, or have a research interest in this area, I invite you to join me in a research collaboration.
Encouraging joint discussion on this issue, I address the following question to the esteemed community of researchers and scientists:
What was the pandemic and post-pandemic impact of the SARS-CoV-2 (Covid-19) coronavirus pandemic on globalisation processes?
What do you think?
What is your opinion on the subject?
Please respond,
I invite you all to discuss,
Thank you very much,
Best regards,
Dariusz Prokopowicz
Did the SARS-CoV-2 (Covid-19) coronavirus pandemic potentially increase opportunities to accelerate processes of pro-climate and pro-environmental transformation of the economy, but unfortunately these opportunities were not taken advantage of?
During the 1st wave of the SARS-CoV-2 (Covid-19) coronavirus pandemic in March 2020, the stock markets crashed. Energy and industrial commodities fell sharply on the commodity exchanges. A stock market crash also occurred on the stock markets. The main factor in the panic on the capital markets was the declaration of a global coronavirus epidemic, or pandemic state, by the World Health Organisation on 8 March 2020. This new term 'pandemic' itself created fear and uncertainty in the context of financial markets and economic processes. During the SARS-CoV-2 (Covid-19) coronavirus pandemic, there were also disruptions to international supply and supply logistics chains, government imposed quarantines and lockdowns imposed on selected sectors of the economy which increased the scale of the 2020 recession. As a result of these mainly interventionist actions by central institutions, a deep economic crisis emerged in 2020, the economy declined in many sectors of the economy, and economic process activity declined. The result of the decline in economic activity was a decrease in demand for raw materials, including energy raw materials. Due to the increase in remote working by employees of many companies from home, the use of cars, especially combustion cars, decreased. As a result, air quality and the state of the environment noticeably improved in 2020. In addition, opportunities have arisen to accelerate pro-climate transformation processes in the economy. Unfortunately, in many countries these opportunities have not been seized. For example, in the country where I operate during the SARS-CoV-2 coronavirus pandemic (Covid-19), the government used printed money to provide financial public assistance to companies and enterprises operating in a wide variety of industries and sectors, not just those in lockdowns, on a historically record scale. Many companies and enterprises that were in good financial standing also benefited from these programmes of non-refundable financial subsidies, employee wage subsidies, tax relief, deferrals of contributions to the social security system and so on. The scale of the granted non-refundable public aid realised on the basis of printed money introduced extra-budgetarily by government funds created especially for this purpose was so large that inflation began to rise in Poland almost from the beginning of 2021. Citizens invested the extra, free money in shares and flats, which caused an increase in the prices of these assets. On the other hand, opportunities to accelerate the processes of pro-climate transformation of the economy were missed by the government. Subsidies for the development of renewable energy sources were not increased and were even reduced on some issues. Since April 2022, the government has reduced subsidies and worsened the economic conditions for the installation of photovoltaic panels by citizens on the roofs of their houses. There is a lack of subsidies for insulating the facades of buildings and single-family houses, installing photovoltaics, installing heat pumps and other renewable energy solutions. Poland has still not met the European Union guidelines for receiving EU subsidies to finance projects that could be implemented under the National Reconstruction Programme. As a result, the development of renewable and emission-free energy sources has slowed down instead of accelerating as it could have done during the pandemic. Unfortunately, still the process of pro-environmental and pro-climate transformation of the energy sector is progressing much slower than it could if the issue of green transformation of the economy was not ignored in the political and business spheres in Poland. The result of these omissions, neglect and ignorance is the current low level of energy independence and security in Poland in the context of the currently developing energy crisis. The result of this neglect is also the poor air quality in Poland. Poland has one of the worst air quality in the world. Poland is one of the 3 countries in Europe with the highest mortality rate caused by poor air quality polluted with various toxins resulting mainly from the dominant dirty energy industry based on burning fossil fuels. In addition, even more negative consequences of these omissions, negligence and ignorance appear in the future, when the process of global warming will significantly accelerate in the next decades and lead to a worsening of the climate crisis and to a climate catastrophe, which may already occur at the end of this 21st century.
The potential for accelerating the processes of pro-climate transformation of the economy that occurred during the SARS-CoV-2 (Covid-19) coronavirus pandemic was described in my publications, which I posted on my profile of this Research Gate portal after publication:
What does it look like in your country?
Did the SARS-CoV-2 (Covid-19) coronavirus pandemic potentially increase opportunities to accelerate processes of pro-climate and pro-environmental transformation of the economy, but unfortunately these opportunities were not used?
Please respond,
I invite you all to discuss,
Thank you very much,
Warm regards,
Dariusz Prokopowicz
Look around you and count how many black offices for solving the exams and assignments are there.
From my point of view, e-learning alone will not succeed without traditional learning. Furthermore, I see that e-learning hasn't achieved the desired aims or results for developing countries and traditional learning is better. This is because there are many black offices for solving exam questions!! These offices made online learning a trading stock that resembles the slave-market.
At least, the hybrid learning of both of them is better than the traditional one.
In any way, exams must be inside the educational institutes with the physical attendance of the students.
Please share your experiences so we all can get better.
The SARS-CoV-2 (Covid-19) coronavirus pandemic has, in some respects, through interrupted chains of international supply and supply logistics, reduced the scale of economic globalisation processes. On the other hand, the need for the development of remote Internet communication has increased due to the introduction of home quarantine periods and lockdowns imposed on selected sectors of the economy in 2020. Consequently, the scale of internetisation and digitalisation of various aspects of business conducted by companies and enterprises has increased. As a result of the growth of the Internet, the importance of information globalisation has increased in terms of remote Internet-based communication. In a multi-year perspective, the importance of environmental and pro-climate globalisation may increase in the future. In view of the above, how else will globalisation processes change in this decade of the 21st century? Will the current energy crisis, the unfolding food crisis, the migration crisis
What is your opinion on this?
What is your opinion on this topic?
Please reply,
I invite you all to discuss,
Thank you very much,
Best regards,
Dariusz Prokopowicz
Some recent studies have documented COVID-19 being zoonotic. Online documents show china testing fish for the coronavirus. How ever, pets such as cats and dogs rarely show the signs of the disease even after infection, though there can still shed the virus to humans. To this effect, what preventive recommendation should be done against transmission of the virus between pets and humans. Is it possible fo the vaccine administered to humans also be administered to pets?
Dataset: http://dx.doi.org/10.21227/781w-ef42
This dataset includes CSV files that contain the tweet IDs. The tweets have been collected by the model deployed here at https://live.rlamsal.com.np. The model monitors the real-time Twitter feed for coronavirus-related tweets, using filters: language “en”, and keywords “corona”, "coronavirus", "covid", "covid19" and variants of "sarscov2".
As per the Twitter Developer Policy, it is not possible for me to provide information other than the Tweet IDs (this dataset has been completely re-designed on March 20, 2020, to comply with data sharing policies set by Twitter). Note: This dataset should be solely used for non-commercial research purposes. A new list of tweet IDs will be added to this dataset every day. Bookmark the dataset page for further updates.
Dataset status as of May 24, 2020: 116,962,112 Global Tweets (EN)
Coronavirus disease (COVID-19) pandemic is a global health problem. Infected patients usually have respiratory symptoms due to lung involvements. However, liver impairments could be another findings.
So does Covid-19 affect liver functions & how?
Those who recover from the coronavirus are probably not going to catch it again, at least in the short term, experts say. But it's unclear how long that immunity will last.
Considering the US negative Oil Price and Also the Global Average Oil Production Cost that Range between $30 to $40 a Barrel, Please Share your Perspective Regarding the Future of the Oil Prices, Oil Production and Oil Firms.
"US oil prices crashed into negative territory for the first time in history as the evaporation of demand caused by the coronavirus pandemic left the world awash with oil and not enough storage capacity — meaning producers are paying buyers to take it off their hands. West Texas Intermediate, the US benchmark, traded as low as -$40.32 a barrel in a day of chaos in oil markets." , reported by FINANCIAL TIMES on April 20, 2020.
Now the most common questions that might be raised in all people's mind is that " Will Oil Price Recover and Oil Industry Survive?? If Yes, When and How this will Occur?? "
Covid-19 live updates.
Which websites, links, and platforms can one use to track Covid-19 live updates?
There are news on COVID-19 outbreak on ship, no matter cruise or military one.
And few aircraft carriers are also involved.
What is special about the ship arrangement that facilitated all these?
Nature 580, 18 (2020)
Limiting spread of COVID-19 from cruise ships - lessons to be learnt from Japan,
QJM: An International Journal of Medicine, , hcaa092,
COVID-19 outbreak on the Diamond Princess cruise ship: estimating the epidemic potential and effectiveness of public health countermeasures,
Journal of Travel Medicine, , taaa030,
Public Health Responses to COVID-19 Outbreaks on Cruise Ships — Worldwide, February–March 2020. MMWR Morb Mortal Wkly Rep 2020;69:347-352. DOI: http://dx.doi.org/10.15585/mmwr.mm6912e3
Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship, Yokohama, Japan, 2020.
Euro Surveill. 2020;25(10):pii=2000180.
Chest CT Findings in Cases from the Cruise Ship “Diamond Princess” with Coronavirus Disease 2019 (COVID-19)
- As of today (April 14th), South Africa has tested a little over 83,000 people in a country of nearly 60 million. That’s about the same population as the UK, who’ve tested around 382,000, or 4.6x as many. But ~24% of tests in the UK came back positive, whereas that rate is only about 2.8% in SA. It seems SA’s lockdown and other measures have been working pretty well so far.
I'd like to know how to search for the list of all the suppliers providing Commercial ACE 2 produced from E.Coli, I want to order it to carry out ACE2-spike protein interactions ?
COVID-19 is the pandemic of the 21st century. It is known to be spread by infectious aerosols produced when speak, cough, breathe or sneeze. Those aerosols can travel a few meters from the source… or much longer distances?
When we look at the images of the growing pollen tubes in the oesophagus of patients during the flowering season1, we can imagine that pollen will be a prevalent emission of any sneeze and cough in Spring. We show in a previous publication that airborne pollen is the main vector for bacteria in the air2. This pollen is passively dispersed long distances. Already Charles Darwin pointed out the ability of pollen to be dispersed thousands of km from the African coast inside the Atlantic ocean3. What about if pollen is carrying bacteria and viruses longer than expected? Some prevalent pollen types are now flying in Europe coinciding with the pandemic expansion of COVID-19. Could pollen being emitted as aerosol by humans also be a vector for diseases?
But other inhaled particles also contribute to increase the amount of emissions when coughing, for example smoke particles or pollution. It is well known how aerosols from smoking are responsible for disease’s dispersion. About pollution, the habit changes and the economical break derived from the pandemic are doing the job. But are we doing enough concerning smoking or vaping?
Because there is no any vaccine for COVID-19 until and in past insects have transmitted number of diseases like; chikungunya virus, yellow fever, dengue fever,Lyme disease, plague,malaria, sleeping sickness, leishmaniasis, filariasis. So, what do you think, could it be possible for COVID-19?
When I discussed some people who once suffered from Coronavirus, they reported some sort of memory loss. I was surprised to know this. Are there any other reported eveidences revealing any type of memory loss in covid suggered people. Kindly share.
Can Coronavirus spread at community level from sewage and drainage?
Nasal Spray for Prevention/Early Treatment of COVID-19 Works in Mice
A newly discovered small molecule could be sprayed into people’s noses to prevent COVID-19 illness prior to exposure and provide early treatment if administered soon after infection. When the molecule was evaluated in mice engineered to display human receptors for the coronavirus, morbidity and mortality were reduced. The encouraging results held across experiments with several SARS-CoV-2
From data released by a team of reseachers across 3 Universities in North America
Which Animal species can transmit the Coronavirus (COVID-19) to humans?
What are the animals incriminated to transmit COVID-19 to humans and how we deal with them to avoid infection?
Sleep is known for its immuno-modulatory and immune strengthening effects. Different sleep stage specific deprivations studies across animal kingdom are found correlated with many patho-physiological, immune-weakening and health detrimental issues. Is the lack of sleep with modern stress and socio-economical changes are driving the immuno-deficiency in humans to combat virus challenges?
An article March 10, 2020 on Annals of Internal Medicine, The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application, estimates a median incubation period of 5.8 days "(95% CI, 4.5 to 5.8 days), and 97.5% of those who develop symptoms will do so within 11.5 days (CI, 8.2 to 15.6 days) of infection."
Are there any updated estimates or more recent reports?
I can see how pandemic has impacted creative abilities of both young and adult learners, by creating isolation from learning. It had negative effects on physical and mental health of students. Do you think that Creativity is consumed by corona? Would you like to comment upon this statement? You are most welcome.
Wearing mask has been inevitable, though not bad, it too has established a mask culture over the world. Along with it arose some major problems, likewise, identity issues, healty issues and bargaining. Production of mask has taken the shape of big profit making Industries. There is a lack of knowledge regarding proper wearing of mask. There is no check on production firms. There should be parameters and specifications on material, size, thickness, etc. for producing masks of good quality. Many a time, wearing a mask creates identity crisis and it may create some other social problems if not handled within time. What do you think about these issues? Kindly share your views and experience.
Is it indispensable to receive a vaccine by the COVID-19 recovered person?
Are the use of inhibitors and interferons could be an excellent preventive measure against COVID-19?
We have ran some Coronavirus samples on MinION using MinKnow with the Guppy basecaller on. Unfortunately, we had to re-run later to get enough reads, however, on this second time we left the Guppy off ! All these using windows 10.
How do I run this last data on Guppy separately, using windows instead of command line? I would appreciate your comments.
Thank you for the help
Regards
Flavio
Some studies showed IgG could appear before IgM in some patients infected with COVID-19. Do these IgGs recognize epitopes shared with the previous coronavirus? Any role for previous memory T-cells?
COVID-19 is mainly a respiratory disease that affects the lung, although other organ structures with endothelium seems to be affected too.
When should we do imaging?
What is the aim of the imaging?
How can it help with management?
Do you agree with the following consensus statement?
How will you adjust your own practice and difficulties encountered? Why?
Ref:
The Role of Chest Imaging in Patient Management during the COVID-19 Pandemic: A Multinational Consensus Statement from the Fleischner Society. Chest. 2020 Apr 07.
She left school at 16 without completing her formal education, became a pioneer of virus imaging, and identified and imaged the first coronavirus in 1964. More than half a century after the discovery, her work has come roaring back into focus during the present pandemic.
Has this been done with current vaccines and do you have links to the research to provide us with?
Double-blind clinical trials for coronavirus COVID 19.
COVID-19 is changing the social life of all people. Jumping out of the personal aspect, how does it affect the family as a whole.
Family is regarded as the fundamental structure of the society, will COVID-19 changes the future family structure, unit and model?
How is it affecting gender issues too?
Besides, why is domestic violence increasing? Is psychology and psychiatry playing a role?
reference:
[1] Campbell AM. An increasing risk of family violence during the Covid-19 pandemic: Strengthening community collaborations to save lives.
Forensic Science International: Reports vol. 2 (2020): 100089.
[2]COVID-19: Reducing the risk of infection might increase the risk of intimate partner violence
EClinicalMedicine
[3]The pandemic paradox: The consequences of COVID‐19 on domestic violence
J Clin Nurs
The question of how computers can contribute to controlling the COVID-19 pandemic is being posed to experts in artificial intelligence (AI) all over the world.
AI tools can help in many different ways. They are being used to predict the spread of the coronavirus, map its genetic evolution as it transmits from human to human, speed up diagnosis, and in the development of potential treatments, while also helping policymakers cope with related issues, such as the impact on transport, food supplies and travel.
But in all these cases, AI is only effective if it has sufficient examples to learn from. As COVID-19 has taken the world into unchartered territory, the "deep learning" systems, which computers use to acquire new capabilities, don’t necessarily have the data they need to produce useful outputs.
Has anyone studied the effects of rheumatic drugs on the coronavirus?
I read the article
and see that many specialists place great hopes on drugs for rheumatic diseases in the treatment of covid. The article is from the beginning of the pandemic and I am interested in whether there is confirmation of the hopes written in the article. Is there new data and progress in this direction?
The rapid pace of deforestation, urbanisation and road building are major factors in the spread of infectious diseases across Asia, including the coronavirus.
Worldwide, more than 119,000 people have been infected by the Covid-19 coronavirus, which emerged from China late last year, and more than 4,200 have died, according to a Reuters tally.
Coronaviruses are zoonotic diseases or zoonoses - meaning they are passed from animals to humans. Other examples include the Severe Acute Respiratory Syndrome that was transmitted from civet cats, the Middle East Respiratory Syndrome that was passed from camels, as well as Ebola and bird flu.
"Diseases passed from animals to humans are on the rise, as the world continues to see unprecedented destruction of wild habitats by human activity," Doreen Robinson (the United Nations Environment Programme UNEP) BP, Marc,2020.
There are indications that mouthwashes could reduce the risk of coronavirus transmission. Do you have any solid information about this?
What do you think about the origin of the new coronavirus (COVID-19)?
Now there are different reports about the main origin of the coronavirus. Some media say the virus may have been synthesized in the laboratory.
What do you think about this? Will the virus soon be cured or vaccinated? Please share your comments.
Hello to all
About 3 months ago, I asked this question, but I didn't get a comprehensive answer.
Can a person who has had Coronavirus disease (COVID-19) get infected again?
Coronavirus Worldwide peak will come next winter
scientific model predicts
It has been seen that many deaths of older people happened due to coronavirus, younger was found infected and then recovered yet no any case or less cases or children affected by coronavirus was reported. Anyone have any information or suggestions???
A new study has found that the new coronavirus, named SARS-CoV-2, didn't spread as efficiently in warmer and more humid regions of the world as it did in colder areas. Though the early analysis, published in the journal Social Science Research Network, is still under review, it provides a glimpse into what we might expect in the warmer months to come.
For a comparative study of legislative activity during the coronavirus pandemic, we are looking for experts who can report about the current operation of the legislature in their country.
We will be most grateful for links to relevant experts, particularly from countries outside Europe and North America.
If you can suggest relevant experts, please write me privately at Ittai.Bar-Siman-Tov@biu.ac.il
Thank you very much in advance,
Ittai
Have you ever imagined how the physically disabled people feel under COVID-19?
Which type of disability is most impacting these minority under COVID-19?
Autism? Cleft patients? Mental health patients? Deaf? Dumb? Blind? Loss of limbs?
How can we help them?
his is what you need to know about coronavirus immunity and contracting the virus more than once.
increasing temperature in summer makes people spending more time indoors to seek relief in the air conditioning. Can air conditioning facilitates contribute in spreading coronavirus?
Changes in social protection sphere are almost inevitable in many countries during and after Coronavirus crisis. What are they?
Please anyone can help me by answering this question. I would like to have information concerning the mode of transmission of this Virus. Is this transmission will be from human to human only? I want to know if animals such as cats can carry this Virus and transmit it to humans.
Stress, diabetes, hypertension, depression, and other chronic illnesses.
For example, not changing shoes when coming home and thus bringing tons of viruses from outside.
Walking bare-feet via security at airports,
Instead of putting on disposable covers on their feet, etc.
The current study shows that blood group A people has a higher susceptibility to SARS-CoV, SARS-CoV-2 and COVID-19 [1].
The explanation is that presence of anti-A antibody in blood group B and blood group O people can inhibit the adhesion of Spike protein to ACE2 receptor on the host cell surface [2].
However, this study showed that blood group AB people didn't have a higher susceptibility to COVID-19. However, there is no anti-A antibody in blood group AB people too. Therefore, we should expect that both blood group A and blood group AB people have a higher susceptibility tocoronavirus.
How can we explain if anti-A antibody played an important role in the infection of coronavirus without considering the situation in blood group AB people?
References:
[1] Zhao, Jiao, et al. "Relationship between the ABO Blood Group and the COVID-19 Susceptibility." medRxiv (2020).
[2] Guillon, Patrice, et al. "Inhibition of the interaction between the SARS-CoV spike protein and its cellular receptor by anti-histo-blood group antibodies." Glycobiology 18.12 (2008): 1085-1093.
With unprecedented and devastating effect, do you think corona virus outbreak can contribute reshaping global order?
Ref:
One reason for posting this question is to hope that by following this question it is possible to keep up on developments pertaining to this question.
An article in a health magazine, Stat, by Sharon Begley, Experts envision two scenarios if the new coronavirus isn’t contained, suggests the answer for now is, not sure.
An article in Lancet, Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study, by Prof. Joseph T. Wu, Kathy Leung, and Prof. Gabriel M Leung, remarks in the discussion portion of their paper that `independent self-sustaining human-to-human spread is already present in multiple Chinese cities’ including global transport hubs. This suggests that containing, confining and eliminating COVID-19 as a pervasive and ongoing infectious disease might not be possible.
If infected people do not acquire immunity, that affects calculations of the ongoing spread of COVID-19. For example, if 70% of a population catches COVID-19 and most survive and acquire immunity, then the size of the group that COVID -19 could newly infect would be smaller. In that way, over time, as the number of people who survive the disease increases, the rate of new infections might decline because there would be fewer people without acquired immunity. I wonder what epidemiology says? These issues also affect hopes for a vaccine.
Regardless of what the immunity situation is, it seems to be that there should be a permanent cultural shift away from greetings such as handshakes and kissing.
In the current pandemic situation, it is not possible to completely avoid a psychiatric patient carrying COVID-19 or being directly symptomatic. In addition, medical priority is to help anyone. How is your psychiatric clinic prepared for this situation? What is the experience of Italian psychiatrists or psychiatrists from other countries of the world (China, European states?)
COVID-19 infection is currently superior to any mental disorder, but what is your management of an acute psychiatric patient with a positive epidemiological history or clinical symptoms? I am very curious about your opinions, comments and observations.
Salam (Hello)!
We have prepared some new compounds with important potential to inhibit viruses.
We are interested in inhibition of Hepatetis-B/C, Nipah, Nil and coronavirus.
Who can collaborate with us in Virology?
ALLAH HAFIZ
Taibi BEN HADDA
Makkah/KSA and Oujda/Morocco
Hi all.
I am conducting research that is intending to compare if requests to a call center for a service are statistically significantly different from 2019 as compared to 2020, due to coronavirus interventions that took place in the year. What would the most appropriate test in SPSS be to run to determine this?