Science topic

Connective Tissue - Science topic

Tissue that supports and binds other tissues. It consists of CONNECTIVE TISSUE CELLS embedded in a large amount of EXTRACELLULAR MATRIX.
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Publications related to Connective Tissue (10,000)
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Article
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As the living tissue connecting urban places, streets play significant roles in driving city development, providing essential access, and promoting human interactions. Understanding street activities and how these activities vary across different streets is critical for designing both efficient and livable streets. However, current street classific...
Article
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Background: To compare the efficacy of Ex-PRESS implantation versus trabeculectomy combined with phacoemulsification. Methods: A retrospective 12-month study on patients with coincident primary open-angle glaucoma (POAG) and cataract. The patients underwent combined phacoemulsification and Ex-PRESS implant (Phaco-ExPRESS, n = 35) or phacotrabecu...
Article
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A collision tumor is a neoplastic lesion comprised of two or more distinct cell populations with distinct borders. Desmoid fibromatosis (DF) is a rare musculoaponeurotic tissue tumor that grows deep in the connective tissue and shows locally aggressive behavior. Only two cases of collision tumors with desmoid fibromatosis are reported in the Englis...
Article
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Background Environmental exposures have been associated with the juvenile idiopathic inflammatory myopathies (JIIM). We undertook a questionnaire-based study to evaluate patient-reported exposures as possible risk factors for JIIM. Findings One-hundred-seven patients with JIIM were enrolled in a myositis natural history protocol and completed envi...
Article
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Background Stickler syndrome (STL) is a rare, clinically and molecularly heterogeneous connective tissue disorder. Pathogenic variants occurring in a variety of genes cause STL, mainly inherited in an autosomal dominant fashion. Autosomal recessive STL is ultra-rare with only four families with biallelic COL9A3 variants reported to date. Results H...
Article
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Purpose Injectable connective tissue matrices (CTMs) may promote tendon healing, given their minimally invasive properties, structural and biochemical extracellular matrix components, and capacity to fill irregular spaces. The purpose of this study is to evaluate the effects of placental CTMs on the cellular activities of human tenocytes. Decellula...
Article
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Background Vascular Ehlers-Danlos syndrome (vEDS) is a rare inherited connective tissue disorder due to pathogenic variants in COL3A1 leading to medium-size-artery (MSA) dissection, aneurysm, rupture. Aortic lesions are rarer and less investigated. The objective was to describe the distribution of MSA and aortic lesions and the type of COL3A1 varia...
Article
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Background Coronavirus disease 2019 (COVID-19) is a pandemic disease which predominantly affects the respiratory system with high critical care mortality and morbidity, yet it also causes multiple organs dysfunction in affected patients. There is a strong evidence that it increases the susceptibility of cerebrovascular strokes in such patients. Bes...
Article
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Tarsal tunnel syndrome (TTS) is a common entrapment syndrome whose diagnosis can be difficult. We compared preoperative magnetic resonance imaging (MRI) and operative findings in 23 consecutive TTS patients (28 sides) whose mean age was 74.5 years. The 1.5T MRI sequence was 3D T2* fat suppression. We compared the MRI findings with surgical records...
Chapter
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Breast cancer (BC) is one of the most common types of cancer and the leading cause of morbidity and mortality in women across the globe. The associated mortality and morbidity account for more therapeutic approaches. The development of therapeutic resistance is one of the most serious clinical issues experienced during the treatment of BC patients....
Article
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Despite an essential differential diagnosis for fever of unknown origin (FUO) in young adults, adult-onset Still’s disease (AOSD) is infrequently considered and remained underdiagnosed in low-middle-income countries. The present study analyzed the clinical, serological, radiological, and pathological characteristics of AOSD presented as FUO in Indi...
Article
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Aim. To identify risk factors for pelvic organ prolapse in females after hysterectomy. Materials and methods. A cross-sectional study from August 2019 to October 2021 in women after hysterectomy for benign neoplasms (n=91) analyzed history, outpatient medical record data, and clinical examination findings. Pelvic organ prolapse was assessed using...
Article
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Background This study evaluated and compared the expression of VEGF, CD34, and α-SMA in the anterior cruciate ligaments and medial collateral ligaments in healthy human knees in order to enrich the epiligament theory regarding ligament healing after injury. Methods Samples from the mid-substance of the anterior cruciate ligament and the medial col...
Article
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Synthetic hydrogels represent an exciting avenue in the field of regenerative biomaterials given their injectability, orthogonally tunable mechanical properties, and potential for modular inclusion of cellular cues. Separately, recent advances in soluble factor release technology have facilitated control over the soluble milieu in cell microenviron...
Article
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Purpose of Review To provide a comprehensive overview of the spectrum of large and medium vessel vasculitis in adults with primary vasculitides, arthritides, connective tissue, and fibroinflammatory diseases as well as vasculitis mimics, for an efficient differential diagnosis and initial diagnostic approach. Recent Findings Imaging has had a trem...
Article
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Background: Damage to the tricuspid valve (TVD) is now considered either a major or minor complication of the transvenous lead extraction procedure (TLE). As yet, the risk factors and long-term survival after TLE in patients with TVD have not been analyzed in detail. Methods: This post hoc analysis used clinical data of 2631 patients (mean age 66.8...
Article
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Connective tissue ageing is accelerated by the progressive accumulation of advanced glycation end products (AGEs). The formation of AGEs is characteristic for diabetes mellitus (DM) progression and affects only specific proteins with relatively long half-lives. This is the case of fibrillar collagens that are highly susceptible to glycation. While...
Chapter
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Os carboidratos são biomoléculas capazes de fornecer energia para a maioria das células não-fotossintéticas. Essa transferência de energia acontece devido ao processo de oxidação dos carboidratos. Os carboidratos apresentam diferentes funções, incluindo: proteção e formação da estrutura da parede celular e tecido conjuntivo, servem como lubrificant...
Article
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Background Perifascial areolar tissue (PAT) transplant is a method of transplanting loose connective tissue harvested in a sheet form from above the fascia to the wound bed and is effective for wounds with exposed ischemic tissue. However, the engraftment mechanism is unknown, and no animal models of PAT transplant for wound healing exist. Methods...
Article
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Background and Objectives: Jejunal artery (JA) and ileal artery (IA) aneurysms constitute less than 3% of all visceral artery aneurysms (VAAs), carrying a risk of rupture as high as 30%, and a mortality of 20%. Though many etiologies have been reported in the literature, no mention exists on a causal association between these aneurysms and inflamma...
Article
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The lesion resulting from the interaction between Mycobacterium and the host immune response is the tuberculous granuloma. Tuberculous granulomas, except in incipient stages, are partially or totally encapsulated by connective tissue. The aim of this study was to assess the immunoexpression of the extracellular matrix proteins fibronectin, collagen...
Article
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Background and objectives: The study aimed to evaluate and compare the amount of papillary gain and black triangle height reduction after intervention with a microtunnelling technique with either Connective tissue graft (CTG) or Platelet-rich fibrin (PRF) as a biomatrix at 6 months using a microsurgical approach. Materials and Methods: Twenty-six p...
Article
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The intramuscular connective tissue plays a critical role in maintaining the structural integrity of the muscle and in providing mechanical support. The current study investigates age-related changes that may contribute to passive stiffness and functional impairment of skeletal muscles. Variations in the extracellular matrix in human quadriceps fem...
Article
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Objective: Our study aimed to evaluate clinical, functional, and prognostic features and to determine the prognosis of idiopathic pulmonary fibrosis, connective tissue disease-associated interstitial lung diseases, and interstitial pneumonia with autoimmune features. Material and methods: Sixty-nine cases with interstitial lung diseases were recru...
Article
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The lamina cribrosa (LC) becomes shallower as intraocular pressure (IOP) decreases after trabeculectomy. The LC in eyes with exfoliation syndrome has distinctive properties in the connective tissue and extracellular matrix, but how these affect the changes in LC depth in response to IOP reduction after trabeculectomy is unknown. We analyzed pre- an...
Article
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Connective tissue is considered to influence the toughness of pork, but most studies on connective tissue focus on the loin muscle. Cooking loss, Warner-Bratzler shear force (WBSF), texture profile analysis (hardness, springiness, chewiness, resilience and cohesiveness), total and insoluble collagen content, the percentage of type III collagen rela...
Article
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Previous systematic reviews have reported that coronally advanced flap (CAF) + connective tissue graft (CTG) are the gold standard in root coverage procedures (RCP). Nevertheless, adjunctive treatment with hyaluronic acid (HA) has been proposed to aim at improving clinical outcomes and reducing patient morbidity. The aim of this systematic review a...
Article
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The goal of this project was histopathological study the of the xeno-bovine bony implantation (X-BBI), which replaced inthe induced femoral gab in rabbits.10 adults rabbits were used to create1 cmfemoral bone defect,which replaced by X-BBI that prepared from the cortex of calvesulna surgically, the two femoral fragments and the X-BBI fixed internal...
Article
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The cause and pathogenicity of grafting voids following lateral maxillary sinus augmentation (MSA) have not yet been elucidated. The first purpose of this case series is to introduce an unusually large grafting void that radiologically resembles a surgical ciliated cyst (SCC) at the sinus augmented site; the second is to observe the histological fi...
Article
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Background: In maxillofacial surgery, critical size mandibular defects remain a challenging issue. There have been numerous attempts to improve mandibular defect healing. Recently, bone tissue engineering has provided many benefits in improving bone healing. Herein, we tried to investigate the effect of Mineralized plasmatic matrix (MPM) and Chitos...
Article
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Immediate implant placement in the aesthetic area followed by immediate provisionalization is widely used and usually associated with excellent results, if some basic parameters are followed, such as high implant primary stability of the implant, gap fi lling with a biomaterial, delivery of temporary crowns with an adequate emergency profi le and i...
Article
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Orthokeratinized odontogenic cyst is a rare odontogenic cyst which was considered to be a variant of odontogenic keratocyst, but has been recognized as a separate entity due to its varied behavior and histology. Commonly associated with an unerupted tooth in the posterior mandible, it mimics various lesions like dentigerous cyst, odontogenic kerato...
Article
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Gingival recession is defined as the apical displacement of the marginal gingiva in relation to the cemento-enamel junction. It is a common clinical finding in individuals with good as well as those with a poor oral hygiene. It may affect a single tooth or multiple teeth simultaneously. Patients with multiple adjacent gingival recessions present as...
Article
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This paper illustrates a case study and the research hypothesis of a project elaborated by the authors for the city of Gwangmyeong in South Korea. The project, which has been developed as a design concept, consists of an innovative public transportation system that aims to favor social integration between parts of the city that might be potentially...
Article
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For many years optimal treatment for dysfunctional skeletal muscle characterized, for example, by impaired or limited regeneration, has been searched. Among the crucial factors enabling its development is finding the appropriate source of cells, which could participate in tissue reconstruction or serve as an immunomodulating agent (limiting immune...
Article
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bstract: Total number of five liver specimens of golden jackals (two male and three female), with age between 2-4 years, were selected. The liver is the largest internal organ of the body and the largest gland tissue; it is the most important accessory gland in the digestive system. The liver was large lobed gland enclosed by outer layer formed fro...
Article
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Isolated soft tissue enlargements seen in the oral cavity are generally a reactive hyperplasia and rarely neoplastic. Irritation fibroma is a benign tumor of fibrous connective tissue that can be considered a reactionary connective tissue hyperplasia in response to trauma and irritation. It is a gingival lesion of reactive nature with unknown etiol...
Article
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Osteogenesis imperfecta (OI) is a connective tissue disorder characterized by bone fragility. Although the disease severity is known to influence the ability to walk, little is known about how children with severe OI can achieve practical ambulation (PA). This study aimed to determine the early predictors of future mobility in children with OI. Thi...
Article
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Tendons are essential components of the musculoskeletal system that links the skeletal muscle to the skeleton. This dense connective tissue exhibits great plasticity. Therefore, research on the influence of types of exercise, including acute and long-term training, on the structural and mechanical properties of tendons in athletic and sedentary pop...
Preprint
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Diaphragm ultrasound (DUS) has been extensively used in critically ill patients receiving mechanical ventilation while data on its role in outpatients with interstitial lung disease is limited. The aim of this study was to describe the diaphragmatic function, as assessed by ultrasound, in outpatients with Connective Tissue Disease-associated ILD (C...
Article
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Objectives: The objectives of the study were as follows: (1) To find the prevalence of various non-neoplastic skin lesions in our tertiary care hospital. (2) To study the age- and sex-wise distribution of non-neoplastic skin lesions. (3) To compare the results of the present study with other studies. Methods: The present study comprised total 200 p...
Article
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Objective. To detect the features of connective tissue metabolism in healthy women during pregnancy. Materials and methods. The study of the connective tissue components was conducted at the terms of 1516 weeks, 2024 weeks as well as before the labor. Under observation there were 52 pregnant women (main group), who underwent the study of the connec...
Poster
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Lambs' low slaughter weight, and thus, light carcasses are characteristic of Portuguese market. Such carcasses present lower muscle volume and high bone, and some primal cuts require laborious home preparation. Accordingly, lamb meat is appreciated due to its low fat and connective tissue content. The aim of this study was to evaluate the effects o...
Chapter
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Des saignements anormaux peuvent résulter d'anomalies des plaquettes, des facteurs de coagulation ou des vaisseaux sanguins/tissus conjonctifs. Ce chapitre porte sur la diathèse hémorragique congénitale et acquise, et met l'accent sur l'utilisation de produits sanguins spécialisés, de produits de protéines purifiées dérivées du plasma et d'autres n...
Article
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Aim to conduct a comparative analysis of the structure and thickness of the dura mater between men and women in the first period of adulthood and in old age. Material and methods. We analysed the results of the complex morphological study of the dura mater in 91 deceased (49 male and 42 female) aged of 22 to 32 and 75 to 88 years. The deceased were...
Article
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There is genetic diversity of hair types in Inner Mongolia cashmere goat population. Previous studies have found that fibroblast growth factor 21 (FGF21) and PI3K-AKT signal pathways may be related to different hair types in Inner Mongolia cashmere goats. Therefore, the purpose of this study was to explore the effects of PI3K-AKT signal pathway on...
Article
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Background: Vaginal laxity (VL) is characterized by the relaxing of the vaginal wall that affects the quality of life and sexual function of patients. The current management of VL such as Kegel exercises and topical or systemic hormonal replacement results in unsatisfactory outcomes; thus, novel modalities are needed to improve the efficacy. Vagin...
Article
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Tendon is composed of dense fibrous connective tissues, connecting muscle at the myotendinous junction (MTJ) to bone at the enthesis and allowing mechanical force to transmit from muscle to bone. Tendon diseases occur at different zones of the tendon, including enthesis, MTJ and midsubstance of the tendon, due to a variety of environmental and gene...
Preprint
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Background and Purpose: The hamstring muscle shortening occurs in normal person which can lead to movement dysfunction. There is a link between limited flexibility and the development of neuromusculoskeletal symptoms. The Bowen technique is used in connective tissue flexibility. This study aimed to determine the effects of the Bowen technique and s...
Article
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The QT interval is an electrocardiographic measure representing the sum of ventricular depolarization and repolarization, estimated by QRS duration and JT interval, respectively. QT interval abnormalities are associated with potentially fatal ventricular arrhythmia. Using genome-wide multi-ancestry analyses (>250,000 individuals) we identify 177, 1...
Article
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The function of articular cartilage as a load-bearing connective tissue is derived primarily from a balanced interaction between the swelling proteoglycan (PG) matrix and tension-resistant collagen fibrous network. Such balance is compromised during joint disease such as osteoarthritis (OA) due to degradation to PGs and/or collagens. While the PG d...
Article
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Human evolution required adaptation to the boundary conditions of Earth, including 1 g gravity. The bipedal mobility of Homo sapiens in that gravitational field causes ground reaction force (GRF) loading of their lower extremities, influencing the integrity of the tissues of those extremities. However, humans usually experience such loading during...
Article
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Systemic sclerosis (SSc) is a rare connective tissue disorder characterized by immune dysregulation evoking the pathophysiological triad of inflammation, fibrosis and vasculopathy. In SSc, several alterations in the B-cell compartment have been described, leading to polyclonal B-cell hyperreactivity, hypergammaglobulinemia and autoantibody producti...
Article
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Background Chronic heat stress has a negative impact on poultry meat quality. Although this has been extensively investigated, previous studies have primarily focused on metabolic alterations and oxidative stress in the pectoralis major (PM) muscle under chronic heat stress, and not all of the underlying molecular mechanisms are completely understo...
Article
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Background Arterial tortuosity syndrome (ATS) (OMIM #208050) is a very rare autosomal recessive connective tissue disease characterized by elongation, tortuosity, and predisposition of aneurysms formation in medium and large-caliber arteries, vascular dissection, and ischemic events. To date, approximately 100 patients have been reported carrying s...