Science topic
Clinical Nutrition - Science topic
Medical Nutrition Therapy Q&A
Questions related to Clinical Nutrition
Can anyone suggest a SCIE/ Scopus indexed (IF 0.5 - 2.5 preferred) journal in Food Nutrition/ Functional Foods/ Clinical Nutrition categories that accept Reviews?
Especial requirement is the higher number of volumes per annum and lower review time.
Except for the heart failure and the renal disease edema cases
What are the conceptual bases for personalised nutrition?
Dear All,
I hope you are doing well
I wanted to use R to calculate the healthy eating index (2015) based on the NHANES 2018/2018. However, I was unable to locate a guide or r script that demonstrates how to compute the healthy eating index using NHANES 2018/2018. I'm hoping that if anyone knows how to calculate the healthy eating index in R or has an r script that they could share, it would be greatly appreciated.I eagerly await your response.
I am looking for potential collaboration in research about clinical nutrition of patients with liver disease
Dietitians all over the world strive to help fight obesity and other food related diseases. I am sure that most hospitals turn a sharp eye on healthy food according to contemporary knowledge. There are databases covering this topic, e.g. USDA. On the other hand, different patients have different needs relating their diets.
Which software and applications can you recommend for use in a hospital food planning system that takes into account nutritional data for creating healthy diets?
There is some misinformation and myths about the benefits of eating figs and olives, do you have information about studies dealing with this topic?
Dear all
In this situations of carona pandemic what would be the role of Nutrition and nutritionists to combat this ?? Plz enlight if some approches can be made??
Where does the oxidation of the sd LDL take place, Given the high dietary intake of polyunsaturated oils and sugar these days in the face of limited exogenous antioxidants such as vitamin E, lycopene, flavonoids and Coenzyme Q10 which would normally protect the lipoprotein, it would appear that diet may be the major source of oxidised lipids and glycated Apo B in this cardiovascular risk factor.
I have not found specific bibliography on the subject.
Dear all.
Please share the materials and views on canine and feline feeding. In recent times owners prefer to consult doctors more frequently regarding dog foods, quantity to be offered ingredients etc. And many myths are also associated like salt feeding sugar feeding even people dont like to offer milk to dogs. Please put some light and share your experiences in pet feeding.
Please suggest a balanced feedung schedule for dogs and cats.?
Thanks and regards
Partha
Hello,
Many protein shake powder mixes contain digestive enzymes such as protease, lipase, and cellulase. However, the products do not detail from which organism the proteins are produced or which protein homolog is used. I would imagine that the enzymes are produced in yeast or fungi. I am am curious regarding which organisms are used. Also, is the native form of the protein harvested from these organisms, or are they made to produce a recombinant human version? In the case of cellulase, there is no human homolog, so it must be from another organism. Regardless, should not the host species be listed on the product? Additionally, if the protein is not naturally occurring in humans, is it ever a good idea to consume it in high quantities?
Thank you!
I was wondering whether high-fat diet or high-sugar-high-fat diets are more commonly used for diet induced obesity in rodents? And the reasoning behind using one or the other.
When i do a pub-med search i see more hits for 'high-fat diet' for rodents, although there are many different terms for a high-sugar-high fat diet, so its hard to say. I would have expected that HFHS would be more effective.
I'm interested in which is the most effective at inducing obesity, and in particular i'm interested in the effect of the quality of the diet on inducing overeating behaviour. (i'm not planning on conducting experiments, rather looking at the findings in the literature). In general, I'm hoping to get impressions of 'experts in the field' as to what researchers generally use and why...
Many studies reported an association between nutrition and human hearing loss. These studies showed the incidence of hearing loss was increased with the lack of micro-nutrients such as vitamins A, B, C, E, zinc, magnesium, selenium and iron.Moreover, high carbohydrate, fat, and cholesterol intake, or lower protein intake, are responsible for poor hearing status.
Dear colleagues, Any more studies or experience about the relation between nutrition and hearing loss?
Coffee is a simple beverage, but it’s full of complex compounds with health benefits. It contains hundreds of bioactive components including vitamins, minerals, and anti-inflammatory polyphenols such as flavonoids. The amount of caffeine in a cup of coffee can vary, depending on factors ranging from the type of bean used. So, What about the healthy daily amount of caffeine was recommended to be healthy with no risk?
Does anyone have papers of human trials suggesting polyphenols act as synbiotics?
Thanks
I would like to analyse epigenetic changes in response to dietary phytochemical supplementation in humans.
Can anyone explain if this is feasible and how would such analysis be conducted?
Thanks.
The Health Technology Assessment (HTA) unit of the CHU de Québec – Université Laval is currently working to get data on integrated early rehabilitation interventions in pediatric intensive care unit.
We define «integrated early rehabilitation interventions» as physical, functional, nutritional, psychological, communicational, social or spiritual rehabilitation activities initiated during the first days of admission of a patient in the pediatric intensive care unit and delivered by each professional according to an intervention plan that has been developed beforehand as a team by these same professionals.
Are early interdisciplinary rehabilitation interventions an established practice in the pediatric intensive care unit of your hospital?
How do you Control and manage your mood swings without drug therapy ?
Emotional nutrition could be defined as constantly giving you a positive mindset and keeping yourself away from negativity. So, what is the most important for a healthy emotional nutrition ?
Hello there, how are you? I do have a friend working a clinical Nutrition research which is rare to our country and specifically localized to Neonatal ICU. There are a few articles which is directly related to what his is working on but as the result of most of these articles are an observational study he couldn’t get the raw data of exposed and unexposed group or two by two table or something like that to calculate the sample size by using double population formula. He is ask you for your suggestion or ideas what should he do to get a minimum sample size from those papers in reach of these problem.
I have genotype of 400 people, only 102 SNPs. There were target for genetics lifestyle report. They are divided between Brazilians and Swiss.
My research now is to look at few SNPd and calculate a GRS score then to check the differences among these 2 group populations.
From the 102 genes I have selected only 20. We have another data, life BMI, physical activity, age, nationality, and place of residence.
Do you have an ideia, besides basics Statistics and alleles frequency how I can create the GRS scores and calculate more advanced parameters? I have been reading lots of papers, however my background is more clinical nutrition.
Thank you in advance
Viviane
The ketogenic diet has gained popularity as a natural way to lose weight and improve health. The diet is very low in carbohydrates, high in fat and moderate in protein. While the diet is considered safe for most people, it’s associated with some unpleasant side effects.
Would anyone have knowledge or literature references to share on which vitamins or minerals would be beneficial as markers of a healthy diet? The method used is a 48-hour dietary recall and the nutrients used in the analysis should be fairly reliable in a study population of approx. 300.
Off-seasons vegetable offers the higher prices to the farmers. Instead of high price, people preferred off-season fruits and vegetables. It is a general perception that such fruits and vegetables are not good for health. There is any such studies proving the various negative health effects?
Portions of five food groups per day for adults & type 2 diabetics, is there any difference?
some athletes follow the paleolithic diet. paleolithic diet also known as caveman diet. in this diet you have to eat like of a caveman. what is your idea about this diet? can this diet increase the athletic performance? can anyone explain about the aspect of health of this diet?
My clinical study measured the blood biomakers (glucose, insulin, glucagon, GLP-1, GIP, amino acids, etc) at baseline before an intervention meal and at multiple time points after an intervention meal.
We did this measure three times using three different intervention meals at three different days. My main objective is to compare whether there is any difference in the change in blood biomarkers after different intervention meals.
There are several AUC calculation methods to do this, such as the total AUC, incremental AUC (ignore the area under baseline) and net incremental AUC (subtract the area under baseline). How to determine which one to use and what is the rationale?
If someone supplements himself with zinc at a daily dose of 11 mg, does he need to watch out for his dietary sources for zinc content? Or this no upper tolerable with regard to dietary sources? I.E, if someone ingest 11 mg of zinc (supplement form) along with other zinc rich food, will he suffer adverse effects or not?
People these days are becoming sick because of overeating and junk foods and bad food additives, and healthy people are those who eat small amounts. Most people are dying because of diseases linked to food consumption and their number is more than those who are dying of hunger.
Paleo diet method is one of the successful diet method for diabetic, obesity, HT. The main concept of this food method is simple as avoid glucose completely. And there is no restriction for the natural lipid and protein intake.
There are several molecular forms of Cholecystokinin (CCK), of which CCK-8 and CCK-33 are the two frequently used molecular forms in pharmaceutical infusion studies to induce fullness and reduce hunger in human/animals.
However, in dietary studies, which involve participants to consume a test meal, which molecular form of postprandial plasma CCK should we assess? What are the methods available? What are the advantages and disadvantages?
Many dietary studies have not been explicitly stating the molecular form of CCK analysed, although some did mentioned CCK-8, CCK-33 or total CCK being measured.
So how should be make decision around which form of postprandial plasma CCK should be analysed in appetite studies?
which countries in europe are the exporting?
which countries in europe already consuming insects for human use?
which countries are already using insects for animal feed?
how much protein can be supplied by insects in broiler feed?
Ferulic and Vanillic acids are secondary metabolites of anthocyanins. Both can be obtained as food-grade.
Does anyone know what the maximal doses of ferulic and vanillic acids can be given to humans.
Does anyone have know of papers which have provided ferulic and vanillic acid in human intervention studies for cardiometabolic health?
Some studies recommend to add oil to salad dressing to help fat soluble vitamins to be absorbed. Other studies indicate to the dense calories from oils and recommend low or free fat salad dressing and mention to the diets already have fat that help these vitamins to be absorbed and as a healthy nutritional strategy to prevent adding more direct source of oil to foods to avoid weight problems. Other studies and recommendations indicate to add little healthy oil sources to salad dressing such as flaxseed and other source of oil seeds to salad dressing instead of direct adding oils as they seen adding direct oils is a bad strategy to learn children healthy options and to reduce redundant use of oils; also recommend healthy ingredients such as different sources of vinegar and mustard instead of using direct oils in salad dressing. I would like to listen to your opinions.
Best regards
Aly
Sucralose (known as Splenda) is a sweetener from sucrose that was approved by the FDA. It is recommended from many doctors to patients who have sugar problem. It said to be safer and healthy product compared to sugar. However, although my grandparents (85 years old) consumes a lot amount of sugar, they not have any health problem. I am wondering what medical experts think about consuming splenda. We should consume splenda or sugar?
I need to know the effect of cabbage on hyperthyrodism to this parameters lipid -protiens -thyroid hormon-testesteron-liver and kidney function
Anyone know of observational studies of vegetarian / vegan dialysis patients - albumin levels, other clinical outcomes?
I am working on the development of functional yogurt by GABA supplementation. Can you tell me, what is the maximum dose of GABA for not producing any side effect (or toxicity)? And how can we determine that what quantity of oral intake has beneficial effects on CNS?
Smoking cigarette, consuming lots of saturated fatty acids with lots of fruits, vegetables and red wine can lower the incidence of heart disease? so how much of that is true/untrue?
Dear Dietitians and nutritionists what is best diet for rheumatoid arthritis patients?
In a splendid review published in Pediatr Nephrol (2017) 32:921-931 (attached below as pdf) the authors are stressing the pathophysiological mechanisms and the role of gut microbiota in triggering and progressing the CKD among other pathologies as DM or Hypertension.
As possible therapeutic tolls probiotics, synbiotics as well as fecal transplantaton are listed.
Do you have expereince with these therapies and what results did you obtain? Thanks in advance. Kind regards, Michaela
Should we supplement diet with phytosterols, or modify diet, adding nutrition products rich in phytosterols? What products should we enrich diet to provide the right amount of phytosterols per day?
There are many publications on dietary or nutritional risk factors for developing cancer or carcinoma. But there are only few recommendations for post-treatment nutrition, mostly in colorectal cancer. But I didn't find specific recommendations for post-treatment nutrition for people with diabetes mellitus and pancreatic carcinoma.
I thought it is the glycemic index of cooked food that will give a clue for the potential contribution of a given food for the hypoglycemic effect upon ingestion.What is the relevance of estimating the glycemic index of raw food(like uncooked legume grain??)
I would be interested especially in mineral deficiencies / natural treatment through diet
I want to know deep about satiety index and structure index for better balancing of TMR in dairy cow.
Thank You In Advance!!!!
Dear colleague:
we have come up with a simple, inexpensive drug formulation that reverses insulin-dependent diabetes. There is opposition to this finding for two reasons: the formulation contains the nutritional supplement pyrroloquinoline quinone (PQQ) which we show to have vitamin character, a designation journal editors object to.
If taken preventatively, one would expect it to prevent the development of insulin-dependent diabetes. The head of the American Medical Association does not want this information to become public as he fears people would no longer undergo blood glucose testing.
How can I overcome the resistance of journal editors to accept a communication?
Thank you for looking into this
Best regards,
Rudolf Fluckiger, Ph.D
Independent biomedical researcher
Novacule, LLC/ founder and president
2587 Albany ave.
West Hartford, CT 06117
860-519-1621
e-mail: Novacule@gmail.com
There are many factors which affect anthocyanin bioavailability.
However in terms of comparing healthy and disease-state patients, would bioavailability be expected to be greater in healthy subjects post-ingestion of dietary sources rich in anthocyanins?
I need to run offline experimentation about user's daily dietary activity and find a way to classify them based on their adherence.
When having a patient recieving enteral nutrition we reduce the fluid from the IV line of the 24 hour. But do we need to substract the total of the enteral feeding of the total fluids even thought the enteral feed is not a whole sum of fluid because there are solutes, and i sometimes have to go and talk to the nutrition department that the increase the enteral load to fast on a critical patient that needs the IV line for fluid intake regarding specific cases?
there is Harris–Benedict equations with its revised version by mifflin, i m confused which one to use ?
If any, which combination of nutrients can provoke rapid weight gain? Which kind of nutrient supplementation can be combined to achieve this?
Unhealthy diets that contain bacterial lipopolysaccharides (LPS) promote amyloid beta aggregation and healthy diets in the developing world are encouraged to reduce the toxic amyloid beta speices by release of a number of proteins to prevent amyloid beta aggregation.
Magnesium is important to lower cholesterol and maintain the peripheral clearance to toxic amyloid beta. Active lifestyles with exercise reduce magnesium levels with increase risk for Type 3 diabetes. Diets with magnesium supplementation may be important to increase fat metabolism in diabetes.
I am interested in the relationship between diet and FTO gene expression. Most studies have been performed on FTO expression changes in hypothalamus. But as we know, FTO is expressed ubiquitous. We are going to do a research on this subject in adolescents in Iran and I look forward to hearing from everybody that can help us.
Thank you
The major risk of overconsumption of a high fibre diet will lead to excessive intake of phytosterols that lead to neurodegeneration. Diets that are high in fibre in the developing world may also contain toxic xenobiotics that may lead to insulin resistance, NAFLD cardiovascular disease and brain damage.
In general, dietary salt intake was found to be in correlation with arterial hypertension and increased prevalence of cardiovascular diseases, which is endorsed in guidelines of cardiovascular societies and WHO.
On the other hand, decrease of salt intake in patients with heart failure, especially those with hyponatremia was found to increase the mortality, and lower quality of life.
Are there any studies (controlled would be the most desirable), reporting on the effects of sodium diet uptake depending on age, existence of renal disease, COPD, liver failure, diabetes, obesity, or others.
What if you double the water intake, would it not decrease sodium concentration.
Could there be a "salt paradox" similarly to the obesity paradox.
Diets that are calorie sensitive have become important with activation of anti-aging genes that lower glucose levels with the prevention of the induction of NAFLD and diabetes.
Overeating can be controlled by the food restriction procedures that may prevent the consumption of various xenobiotics that may disrupt astrocyte-neuron interactions in the hypothalamus that are responsible for appetite control.
The blood sugar for some diabetics patients may disturb during fasting Ramadan although the take there medication in regular manner, dose change of diet time has a role ?
I have a number of items that I need converting from grams per day to serving per day. Indeed, how much is a serving per day potato as grams per day?
Is anyone aware of a commercially available "nutraceuticals" - compound library for screening in the cell lines?
Dear colleagues, during a recent hypothesis-driven study of type 2 diabetes my research group confirmed our prediction that HbA1c and FBG levels are related to two different early pathophysiological subtypes of type 2 diabetes that may be partly overlapping in later stages. In this case HbA1c and FBG should be considered as independent predictors of different pathologies, but not as interchangeable alternatives as suggested by expert committees in diabetes. Outcome may be different protection management and protecting treatment against the disease development.
Editors of Diabetes and Diabetes Care considered that our finding "does not contain sufficient new or novel information" for sending our submission to external peer review. On behalf of my co-authors I myself would like to reach external peers and appeal for your opinion on this forum. I would appreciate very much if anybody on this forum could help us with a reference to similar finding (i.e., with respect to different pathophysiological subtypes associated with HbA1c and FBG), because I could not find such during my literature search.
FYI: Our pathophysiological subtypes are not among rare subtypes like MODY, LADA and hemochromatosis-related diabetes, as well as are not related to pathophysiological (insulinopenic, hyperinsulinemic, or classic) forms developing later in type 2 diabetes.
Unfortunately, I cannot say more about our findings, because do not lose hope to publish them. Your suggestions in a journal that does not use a modern editorial politics for restricting peer reviewing of submissions like in Diabetes and Diabetes Care are very appreciated.
Thank you.
According to the research of T.Colin Campbell, PHD, cancerous tumors can be nutritionally manipulated. Animal protein promotes tumor growth, while sustaining from animal protein turns the cancer "off".
in case of using parenteral nutrition (central or peripheral) is there any contraindication or any recommendation of using proton pump inhibitors( PPI) or H2- blocker in ICU patients??
Load bearing activities increase the calcium absorption as it prescribed in all osteoporosis cases. Is there any reliable test to measure the absorption after load bearing exercise? Any supportive articles are appreciated.
Kindly, explain your answer. Thanks in advance.
At 2003, the Project Human Genome was finished and many fields of science like nutrigenomics appear but it seems no very practical to use to promote personalized nutrition. have we any papers about this question? i really like to know more about this issue.
We recently acquired a tetrapolar bioimpedanciometry device and our results in terms os body composition percentuals differ a lot from our clinical perception. We understand that clinical perception is not the best way to evaluate body composition, but our results are so unexpected that we'd like to hear from the coleagues theirs experiences and difficulties in this kind of method, in hospitalized clinical ward patiens.
Parents of children with ASD are frequently asking me about Nutrition Therapy for their children. I need some evidences about the topic. Do you agree using Nutrition Therapy for autism? is there any evidence about it?
I have found red cell sodium values (calculated values only unfortunately) to be 'low' - sometimes 'undetectable'. I am guessing that a value around mmol/Litre
