Clinical Medicine - Science topic

Summary Introduction: Urine sediment testing is a diagnostic medicine that remains a long-standing practice in clinical laboratories. Urine analysis, which is an important test in clinical medicine, is used in screening, diagnosing and monitoring diseases of the urinary system, and diseases that are detected through the urinary system. We use the p...

Objective Hypertension, a common chronic disease, often leads to serious complications. While conventional management relies on antihypertensive drugs, which can cause side effects and adherence issues, alternative treatments like herbal medicine are gaining attention. This study examines the efficacy and safety of modified Saengmaeksan, an East As...

MDPI Certificate: Journal of Clinical Medicine (Q1), Sustainability (Q1) , Healthcare (Q2), Medicina (Q2) and International Journal of Environmental Research and Public Health (Q2), Games (Q3

Individuals' knowledge and attitudes about hypertension are important in controlling blood pressure (BP) and reducing hypertension‐related mortality and morbidity. The current study aimed to investigate the effect of hypertension knowledge level on treatment adherence, BP control, and physical activity of hypertensive individuals. This prospective...

The transdermal route is one of the effective routes for delivering drugs. It also overcomes many limitations associated with oral delivery. One of the limitations of this route is the drug’s poor skin permeability—stratum corneum, the skin’s outermost layer that also acts as a barrier for the drug to penetrate. Traditional liposomal formulation is...

Una visión de la medicina espacial aplicada a los viajes al espacio profundo es un reto. A medida que las misiones espaciales aumentan su duración en el espacio y se extienden más allá de la órbita de la Tierra, también aumentarán los riesgos que conlleva trabajar en estas condiciones extremas y aisladas. Los efectos que sufren los astronautas en e...

In this work, an integrated biosensor consisting of spiral microfluidic array and microwave sensors is proposed for simultaneous separation and detection of cells. The biosensor integrated by plasma processing technology is fabricated by soft lithography and glass‐based IC process, which has the advantages of simple preparation, low cost, and relia...

Understanding the regulatory mechanisms of stress-induced immunosuppression and developing reliable diagnostic methods are important tasks in clinical medicine. This will allow for the development of effective strategies for the prevention and treatment of conditions associated with immune system dysfunction induced by chronic stress. The purpose o...

Background/Objectives: Medical therapies that apply biodegradable materials, such as polydioxanone, are widely used to treat various disorders. Thread-embedding acupuncture (TEA) is a unique form of acupuncture that exerts long-lasting therapeutic effects by inserting absorbable threads at specific acupuncture points, and is widely used to treat va...

Purpose/Objective: The transition from childhood to adulthood often involves emotional challenges. These problems may be especially prominent for transition-age adults (TAA) with pediatric-onset disabilities, although there are currently few studies that speak to this. The aim of this study is to characterize depressive symptoms and the association...

Background Hypertonic dehydration is common among older adults and is associated with increased mortality and the incidence of several diseases, such as renal failure and cardiovascular complications. Herein, we aimed to statistically identify risk factors for hypertonic dehydration in older adults in Japan. Methods This cross‐sectional study incl...

Introduction: Urine sediment testing is a diagnostic medicine that remains a long-standing practice in clinical laboratories. Urine analysis, which is an important test in clinical medicine, is used in screening, diagnosing and monitoring diseases of the urinary system, and diseases that are detected through the urinary system. We use the performan...

Background Alzheimer’s disease (AD) is a significant health concern affecting at least 10% of individuals aged 65 and older, with heightened risk in Black and Hispanic/Latino populations. Despite this prevalence, our analysis of University of California Los Angeles (UCLA) electronic health records (EHR) indicates that only 4% of patients aged 65 or...

Patient satisfaction is a level of feeling that arises as a result of the performance of health servicesobtained after being compared with expectations. The aim of this research is to determine the effectof waiting time on patient satisfaction in the outpatient unit (internal medicine clinic) at RSD IdamanBanjarbaru in 2024. The method used is a qu...

The biomechanical analysis of human movement, particularly gait, is crucial in fields such as clinical medicine, sports, and rehabilitation. While traditional motion capture (Mocap) systems are effective, they are often limited by their complexity, high cost, and the unnatural settings they require in terms of the gesture and motion environment. Em...

Family physicians in Ontario provide most of the primary care to the healthcare system. However, given their broad scope of practice, they often provide additional services including emergency medicine, hospital medicine, and palliative care. Understanding the spectrum of services provided by family physicians across different regions is important...

In this review, it is evaluated the progress in the application of stem cell therapy to ameliorate the symptoms of bipolar disorder, major depression, schizophrenia, and autism. These disorders are highly prevalent in clinical medicine and are responsible for high levels of psychosocial disability among patients. All of them share common biomedical...

Medical education plays a critical role in preparing future doctors, responsible for the well-being and health of individual patients. Given its unique significance, understanding how to enhance the intrinsic motivation of clinical medical undergraduates for a 5-year program is a key research focus in China. Based on this purpose, the transformatio...

Exclusive breastfeeding (EBF) for the first six months of life is essential for an infant's optimal growth, immunity, and development. However, global adherence remains inadequate, particularly in developing regions. This study aimed to explore the factors influencing EBF practices among mothers of infants aged 0-6 months attending the immunization...

Creatinine clearance is used to reflect the glomerular filtration rate to assess kidney function. Creatinine degradation-related enzymes have been used for creatinine detection in clinical medicine. The mixture of spores encapsulating either creatininase or creatinase or sarcosine oxidase could mediate a three-step reaction to produce hydrogen pero...

Background The flipped classroom teaching method has been increasingly adopted in recent years for teaching clinical medical specialties in medical schools around the world. However, the outcomes of this approach have not been systematically and quantitatively assessed. This meta-analysis aims to rigorously compare the effects of flipped classroom...

Introduction: Prolonged activation of the body’s stress response from chronic exposure to adverse stressors may have a significant impact on lifelong psychosocial functioning. Screening for the impact of prolonged adversity in childhood has become an integral component of pediatric care. While past research has separately explored the impact of car...

Introduction Medical education typically focuses on the dyadic interaction between patient and physician. However, there is another significant presence in the room that can also impact the patient's health outcomes: caregivers. This topic has been relatively underexplored until now, and there is insufficient information available regarding situati...

This study aimed to investigate the relationship between bone mineral density (BMD) and digit ratio, with the goal of evaluating the potential of digit ratio as a marker for predicting osteoporosis-type bone diseases. The study sample included 200 patients (100 women and 100 men) who visited the Nuclear Medicine Clinic at Cumhuriyet University Rese...

Recent innovations in medical imaging technology have placed molecular imaging techniques at the forefront of diagnostic advancements. The current research trajectory in this field aims to integrate personalized molecular data of patients and diseases with traditional anatomical imaging data, enabling more precise, non-invasive, or minimally invasi...

Automatic ultrasound image segmentation improves the efficiency of clinical diagnosis and decreases the workload of doctors. Many ultrasound image segmentation methods only focus on capturing local details and global dependencies, whereas ignoring large-scale context information. However, it is essential to extract large-scale context features for...

Prostate cancer is a condition of public health significance in the United States. A new method for predicting survival is derived for the domain around the change point from a semiparametric ratio estimator (SPRE) to predict survival in response to treatment for prostate cancer. Using an extended maximum spacing estimator, the geometric mean of sa...

Obesity has emerged as a significant contributor to the development and progression of Peripheral Artery Disease (PAD) which has significant impact on local population as the frequency of obesity is high. Objective: To determine the association between obesity and the development of Peripheral Artery Disease in patients attending General Medicine c...

Introduction: Post-COVID-19 syndrome refers to the occurrence of symptoms lasting more than 4 weeks in individuals who have recovered from COVID-19. This study aims to investigate the post-COVID-19 symptoms in healthcare professionals. Methodology: This descriptive study included 166 healthcare professionals who had tested positive for COVID-19 via...

The wound healing process in patients who were observed for one week showed that 99 cases of patients had experienced a wound healing process that was appropriate to the process, 31 cases of patients experienced an extension of the wound healing process due to various different factors, and 42 cases of patients experienced an infected wound conditi...

AIM: This study aimed to evaluate the effects of vitamin D intake on COPD exacerbation and FEV1 in the patients with severe and very severe COPD. METHODS: This double blind placebo control randomized clinical trial study was done in the Ashayer university hospital in Khorramabad in 2012. Eighty eight patients with severe and very severe COPD were r...

Background Integration of clinical medicine and other subjects has laid more emphasis on the cultivation of high-quality medical talents, with the increasing demand for interprofessional education (IPE). IPE has been promoted by a number of universities to create and sustain authentic IPE activities, with which students can engage. Although IPE has...

Las lesiones musculoesqueléticas son una carga significativa para los sistemas de salud, lo que subraya la importancia de un diagnóstico y tratamiento precisos. Sin embargo, los métodos tradicionales pueden ser limitados en términos de precisión y eficacia. En este contexto, la inteligencia artificial (IA) se ha destacado como una herramienta prome...

Objective. Due to the limited operating space in the magnetic resonance (MR) environment, there is coupled motion in the insertion mechanism, which not only reduces the flexibility of the robot but also challenges the insertion path planning. Meanwhile, the path planning is also restricted by the bending rule of the flexible needle, thus the bendin...

This study aims to analyze the factors that influence current practice of clinical medicine education through questionnaire among the undergraduates of 2003rd year (of graduation) in Luzhou Medical College who have just finished practice education. The sample comprises of 206 students. Then we get the first-hand data based on the personal experienc...

The assessment of lung function is a critical component of clinical medicine, offering insights into the respiratory health of individuals. Spirometry, a key test in evaluating pulmonary function, is commonly used to measure static lung volumes and capacities. Miller, M. R., et al. (2005) [1]. The present study evaluates the use of a student spirom...

The Bachelor of Science in Clinical Medicine (BSc) program in Kenya is critical in training Advanced Clinical Practitioner who serve as the backbone of the country's healthcare system. Over the past decade, the curriculum has evolved significantly to better align with the demands of the healthcare landscape and international standards. This narrati...

Complications have long haunted physicians and patients in clinical medicine. However, the evaluation of complications caused by specific diseases is typically relied on the experience of clinicians or clinical cases. Especially, vast complication diseases involve multiple human body systems, increasing the difficulty of the clinical confirmation....

Background Nuclear medicine is an interdisciplinary field that integrates basic science with clinical medicine. The traditional classroom teaching model lacks interactive and efficient teaching methods and does not adequately address the learning needs and educational goals associated with standardized training for residents. The teaching model tha...

Medical experiment teaching is the basic link of medical education and an important way to train medical students' practical ability and innovative spirit. In recent years, with the continuous development of medical education reform, the teaching reform of functional experiment has become the focus of attention. Based on the basic framework of the...

INTRODUCTION Without disease‐modifying interventions, Medicare and Medicaid spending on Alzheimer's disease (AD) management is expected to reach 637 billion USD annually by 2050. The recent advent of promising AD therapies after decades of a near‐total failure rate in clinical trials suggests that more disease‐modifying therapies are on the horizon...

The bladder or urinary vesicle is an excretory system organ, which can be affected by prolapse, which consists of the displacement of internal organs from their normal anatomical position. This condition can be caused by different factors. Thus, this work reports a bladder prolapse that occurred in an adult specimen, a male Bradypus variegatus, obt...

OBJECTIVES: To evaluate medical students’ interest in basic sciences and identify perceived obstacles for choosing a career in basic science.METHODS: A cross-sectional survey study was conducted and carried out between March and May 2016 with 600 undergraduate medical students at the College of Medicine, King Saud bin Abdulaziz University for Healt...

Introduction: The management of thrombotic risk in clinical medicine has been a longstanding challenge. Oral anticoagulants, specifically vitamin K antagonists (VKAs) like warfarin, have been used for over fifty years. However, VKAs present significant challenges such as frequent monitoring and dietary interactions. Direct oral anticoagulants (DOAC...

Background: Hypertension poses a substantial burden on the healthcare system. Hypertension in adolescents is becoming one of the most common health conditions globally.

Clinical medicine and biological sciences make extensive use of the gene editing method symbolized by CRISPR-Cas9. With the rapid development of molecular biology technology in recent years, the CRISPR-Cas systemwhich stands for clustered regularly interspaced short palindromic repeatshas become a potent tool for gene editing. Due to its high effic...

Ginkgo biloba L., a native of China, enjoys unrivaled fame in the plant world, owing to its multipurpose characters. Ginkgo leave extract contains high levels of flavone glycosides and terpene lactones, which are widely used in orthodox or traditional medicine to treat diseases. However, there are few good Ginkgo varieties for leaf application to d...

Background: Pelvic organ prolapse (POP) has become a common health problem among the aging population and affects an increasing number of elderly women worldwide. Studies within family and twin pairs provided strong evidence for the contribution of genetic factors to POP. Given the incomplete penetrance, polygenic traits, and small effect sizes of...

Cormputed tomography (CT) scanning is an effective medical imaging modality widely used in clinical medicine for diagnosing various conditions. CT can generate three-dimensional images, thus providing more information than traditional two-dimensional radiographs. However, this comes at a cost, as it involves higher radiation, increased expense, and...

Although the importance of scientific research is self-evident, there need to be more physician-scientists1. There is a concern regarding how research interest can be cultivated among undergraduate students. Ahmed et al.2 examined the factors that hinder students from pursuing undergraduate research and the proposed solutions. The authors’ latest r...

The use of liquid biomarkers in clinical medicine are typically employed to gaugeseverity of disease, prognosis and to monitor response to treatment. Whilevarious biomarkers have been employed in clinical medicine with variableperformance characteristics, the use of cell-free DNA (cfDNA) have gainedincreased traction as a novel biomarker in a wide...

Introduction Irritable bowel syndrome (IBS) is one of the most prevalent GI conditions, characterized by symptoms such as abdominal pain relieved by defecation, changes in bowel habits (e.g., diarrhea, constipation, or both), and bloating. These symptoms can profoundly impact the quality of life (QoL) and psychological state of patients. Despite a...

As deoxyribonucleic acis (DNA) nanotechnology advances, DNA, a fundamental biological macromolecule, has been employed to treat various clinical diseases. Among the advancements in this field, tetrahedral frameworks nucleic acids (tFNAs) have gained significant attention due to their straightforward design, structural simplicity, low cost, and high...

Providing a comprehensive look at the state of the art in detection technologies and materials used in the development of diagnostics for clinical, medicinal and environmental applications, the books in this series are a valuable reference for graduate students and professional researchers across academia and industry. Emphasising the detection of...

In the current era, with the development of artificial intelligence, deep learning is an essential branch of it. This paper aims to discuss the development history, application status and development prospect of DL model based on deep learning in medical field. Firstly, the advantages of deep learning are powerful data processing capabilities, impr...

The advent of large language models (LLMs) such as BERT and, more recently, GPT, is transforming our approach of analyzing and understanding biomedical texts. To stay informed about the latest advancements in this area, there is a need for up-to-date summaries on the role of LLM in Natural Language Processing (NLP) of biomedical texts. Thus, this s...

Background In the process of education reform, carrying out continuous educational environment measurement is necessary. This study aimed to evaluate the perceptions of the medical education environment and learning autonomy in blended learning in pediatrics among clinical medicine students, as well as the relationship between these two constructs....

Background Hypertension and muscle strength are known to be associated; however, identifying simple clinical indicators of this relationship is challenging. Relative muscle strength (RMS), defined as strength per unit muscle mass, has been proposed as a potential indicator, but its association with hypertension is unclear. This study aimed to estim...

BACKGROUND: The resistance of Staphylococcus aureus bacteria to antibiotics is still a problem in clinical medicine. The potential of Ant-nest plant extract (Myrmecodia pendans) from the island of Timor as an antibacterial needs to be tested to be used as a new alternative. OBJECTIVE: This study aims to determine the antibacterial potential and dos...

Geometric morphometrics, a powerful method for analysing structural shapes, has become increasingly significant in various disciplines, including anatomy, morphology, and clinical medicine. Unlike traditional morphometric approaches, geometric morphometrics offers a comprehensive understanding of shape structure, particularly when enhanced by 3D im...

Implantable medical electronic devices (IMEDs) have attracted great attention and shown versatility for solving clinical problems ranging from real‐time monitoring of physiological/ pathological states to electrical stimulation therapy and from monitoring brain cell activity to deep brain stimulation. The ongoing challenge is to select appropriate...

Patellar pathologies are a common cause of knee dysfunction, with Patellofemoral Pain Syndrome (PFPS) alone responsible for 25% of knee-related visits to sports medicine clinics. Non-traumatic conditions, while often overlooked, can also lead to significant discomfort and functional limitations, highlighting the importance of accurate and timely di...

Large Language Models (LLMs) have shown remarkable performance across various tasks, yet significant disparities remain for non-English languages, and especially native African languages. This paper addresses these disparities by creating approximately 1 million human-translated words of new benchmark data in 8 low-resource African languages, cover...

Epidemics and outbreaks caused by the dengue virus pose risks to populations and have high mortality rates, causing burdens and economic costs worldwide. Brazil recently experienced an explosive increase in the number of dengue cases and fatalities. Dengue is an acute febrile illness that can progress to severe forms. It affects more than 100 count...

This study aims to analyze the impact of service quality, price, and hospital image on patient satisfaction at the outpatient clinic of internal medicine at K.R.M.T. Wongsonegoro Hospital in Semarang. The research employs a quantitative approach, collecting data through questionnaires distributed to patients receiving outpatient services. Responden...

Post-surgical pain management and patient rehabilitation play crucial role in identifying factors explaining postoperative pain, thus reducing the risk of complications, prolonging the healing process, and enhancing the patient’s quality of life during rehabilitation. These are non-opioid analgesics, minimally invasive procedures, multimodal pain m...

This editorial discusses an article recently published in the World Journal of Clinical Cases , focusing on risk factors associated with intensive care unit-acquired weakness (ICU-AW). ICU-AW is a serious neuromuscular complication seen in critically ill patients, characterized by muscle dysfunction, weakness, and sensory impairments. Post-discharg...

The application of advanced artificial intelligence (AI) models and algorithms in clinical laboratories is a new inevitable stage of development of laboratory medicine, since in the future diagnostic and prognostic panels specific to certain diseases will be created from a large amount of laboratory data. Thanks to machine learning (ML), it is poss...

Objective: To evaluate the usefulness of cervical funneling as a predictor of successful labor induction in term pregnancies. Design: Case-control study. Institution: Hospital Central de Maracaibo, Venezuela. Participants: Pregnant women who underwent labor induction. Methods: Pregnant women were evaluated by ultrasound to establish the presence or...

Estimating comparison functions is crucial in numerous domains, such as econometrics, clinical medicine, and public health, where evaluating the effectiveness of interventions or treatment effects is a central concern. While the response variables are much more expensive to collect than the covariates in many scenarios, to tackle the challenge of l...