Chronic Disease - Science topic
Chronic Disease are diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
Questions related to Chronic Disease
For example, I want to know how baseline characteristics of patients (age, BMI...) and the confounding factors (smoking, diabetes or other chronic diseases) affect the serum vitamin D value. Which regression model should I use?
I use SPSS and R for analyzing the data
Dear community of researchers,
I am currently working on a small research project that will explore community- and patient-led strategies for increasing referral of diabetes and hypertension and raising awareness of these two diseases in Mozambique, a highly resource-constrained country.
I would like to ask:
- does anyone have knowledge on patient-led referral strategies and advocacy activities? If so, could you please share any relevant links and/or are you aware of any recommendations on this from international health organisations?
- do you believe that involving patients in such activities would be ethically appropriate? Why/ why not?
Thank you in advance for any replies.
Is it medically possible to have a single treatment for all diseases? One way to proceed about it is anti-aging. Aging is a process of accumulation of impairments of aging throughout life and ongoing damage of aging. If we can nullify it, our body intrinsic ability to heal would tale over, and provide a healthier system.
Kindly answer to this question with best of your knowledge. For the ongoing covid pandemic and upcoming chronic disease epidemic, we can provide a better treatment if this method works.
What are the most common urine and blood tests required for diseases diagnostics and before drug dosing prescriptions?
The metabolic syndrome is characterized by dyslipidemia and hypertension in obese individuals. Lipoprotein subfractionation of plasma from obese individuals indicate the presence of large very low density lipoprotein, small dense low density lipoprotein and decreased high density lipoprotein. Other defects in obesity and Alzheimer’s disease may be linked to specific lipid species. In obesity and Alzheimer’s disease toxic ceramides are found in these chronic diseases and linked to inflammation, insulin resistance and amyloidogenesis. The search for lipids associated with longevity has accelerated to extend lifespan in the developing and developed world and specific lipids by LIPIDOMICS in the plasma need to be identified to determine the lipids involved in cell signalling associated with healthy aging.
1. Victor Bustos and Linda Partridge. Good ol’ fat: links between lipid signaling and longevity. Trends Biochem Sci. 2017 Oct; 42(10): 812–823.
2. Duffy J., Mutlu A.S., Wang M.C. (2017) Lipid Metabolism, Lipid Signalling and Longevity. In: Olsen A., Gill M. (eds) Ageing: Lessons from C. elegans. Healthy Ageing and Longevity. Springer, Cham.
3. Constantinou, J.K., Southam, A.D., Kvist, J. et al. Characterisation of the dynamic nature of lipids throughout the lifespan of genetically identical female and male Daphnia magna. Sci Rep 10, 5576 (2020).
4. Pradas et al. Exceptional human longevity is associated with a specific plasma phenotype of ether lipids. Redox Biology. Volume 21, February 2019, 101127
5. Lim WLF, Huynh K, Chatterjee P, et al. Relationships Between Plasma Lipids Species, Gender, Risk Factors, and Alzheimer's Disease [published online ahead of print, 2020 May 26]. J Alzheimers Dis. 2020;10.3233/JAD-191304. doi:10.3233/JAD-191304.
6. W. L.Florence Lim, I.J. Martins, R.N.Martins. The involvement of lipids in Alzheimer's disease. J Genet Genomics. 2014; 41(5):261-74.
7. Martins IJ, Creegan R, Lim WLF and Martins RN. (2013). Molecular insights into appetite control and neuroendocrine disease as risk factors for chronic diseases in Western countries. Special Issue. Molecular Mechanisms Involved in Inflammation and Insulin Resistance in Chronic Diseases and Possible Interventions. Open Journal of Endocrine and Metabolic Diseases. 3;11-33.
As medical advances are made in the care of patients with chronic diseases including those with (ESRD), patients are not only experiencing increasing life expectancy but also bearing the burden of illness and treatment methods for a long duration of time. Therefore, it is important for health care providers to pay more attention to their individual patient's perceptions of their life satisfaction, health, fitness, and well-being. Health-Related Quality of Life (HRQOL includes an evaluation of the patient's level of satisfaction with treatment, outcome, and health status, also taking into account their perspective on future prospects. How we can measurably improve health-related quality of life in hemodialysis patients?
Recently I have been able to discuss happiness in life with chronically ill patients (I am a research director at a private cancer foundation). We have realized that both good and bad things happen in life. What seems essential in life is how you react to these events. If events of life (good and bad) are received honestly accepting them as they emerge, then it is possible to experience deep happiness, peace of mind, and joy every day. Even if you are burdened by a chronical disesae.
In the event of difficulties we can learn from good and bad happenings. It seems paramount to find the keys of success in all events of life (good or bad). When good things happen in life, then there is a clear reason to be genuinely grateful and to feel genuine happiness.
We are learning step by step the secrets of a good life by accepting the things that happen to us.
Let’s think about this simple but important thing leading to a happy life: self-acceptance.
I am grateful for any comments and suggestions from you.
I am finding COVID19 Patient's Hospitalization Dataset where the data has Patients Symptoms, Chronic Diseases and Death or survive .
I have a special issue entitled "Deep Learning for Chronic Disease Diagnosis, Prediction, Monitoring, and Treatment."
The issue has the following link:
You are welcome to submit your research papers in this issue. Please note that the Diagnostics
Journal has 3.110 impact factor.
Now-a-days, food safety is a major concern to the consumers. The consumers are interested to buy safe food to enjoy a healthy life. However, in the recent years, the concept of organic food is introduced. It is well known that for the production of organic food all type of chemicals are strictly prohibited. Therefore, it is a little bit difficult to produce organic food. Could you please clarify that what are the major differences of safe food and organic food? Do you agree that the consumption of safe food is enough to ensure a sound and healthy life?
I am looking for a valid and reliable way to measure the medication/drug use, adherence and interactions to evaluate the efficiency of an intervention to reduce inappropriate polypharmacy. Any ideas or experiences with self-assessment questionnaires that are suitable for (older) patients with chronic diseases?
I am checking the barriers and facilitators to retention in care for chronic disease. While doing the literature review I found some studies used grounded theory while some used phenomenology.
Which is more appropriate in my research question?
Any suggestions would be much appreciated.
Thank you and warmest regards
With coronavirus cases increasing every day, countries are installing various methods to curtail the effect of the virus spread. Disinfection is considered as one of the ways to keep the virus in check. Countries including Turkey, Thailand, China, Vietnam and even some parts of India have installed disinfection tunnels with the aim of keeping the virus away. Please put your views on the below questions.
1. Is it safe?
2. Is it Effective?
3. Is there any long term hazard of disinfection spray like invitation to chronic disease?
4. is it safe for skin and eyes?
5. How poor designs of tunnels in India is making it worst?
your answers and thoughts will help.
please spread awareness and block opportunistic thoughts in these critical times..
StayHome is the advice that various agencies offer to tackle a Coronavirus infection, which will increase the degree of inactivity in individuals.
- What is the best methode to face the sedentarity behavior in this moment?
- How can people with chronic diseases cope with inactivity at home?
Using an online health care system can improve the treatment plan for many diseases such as chronic diseases.
Trust factors for these systems can be compromised such as privacy.
What are the most important factors to gain trust in the oniline healthcare system for chronic diseases?
1. Indian Spices and Biotherapeutics in Health and Chronic Disease. Health, 10, 374-380.
2. Indian Spices and Insulin Therapy in Diabetes and Neurodegenerative Diseases. J Diab Clin Stud. 2018; Volume 1(1).
3. Indian spices and Caffeine treatment for Obesity and Cardiovascular disease. Ann Clin Endocrinol Metabol. 2018; 2: 010-014.
4. Indian Spices and Unhealthy Diets interfere with Drug Therapy in Diabetes and Neurodegenerative Diseases. NAPDD 002 2018; 3(4):555616.
5. Insulin Therapy and Autoimmune Disease with Relevance to Nonalcoholic Fatty Liver Disease. Non Alcoholic Fatty Liver Disease. An Update. IntechOpen. October, 2018.
6. Simplicity in complexity: Ian James Martins’ research on insulin therapy and autoimmune disease with a special focus on NAFLD. The Scientific News, Advances in Treating Diseases. November Edition, 2018; REPORTED BY Annie B. Coulter. RECEIVED BY WORLDWIDE AUDIENCE: 84,287,977, 2019.
Newbie researcher with a looming research-induced panic attack - I'm in need of some guidance.
My research project is focusing on how social interaction influence the self-management of chronic disease by baby boomers.
I would like to do a mixed methods study with a case study.
Could anyone suggest any robust ways to flesh out this methodology?
As nutrigenetic and nutrigenomic understanding is increasing should resources still be spent on developing population-wide recommendations for longevity, prevention of chronic disease and treatment of chronic disease?
Sleep is biological function, its repetitive routine of day and night, its time of sleeping, quality of sleeping, ageing and chronic diseases like depression affect more of that, how can we manage insomnia or sleep disorder with physiological or pharmacological manners, this is very important issue in the world, reviews and articles related to general physiology and its control,
Longevity and ageing is new era for study, so these are interchangeable, what are major differences between these, how can we live remaining life with safe and free from chronic diseases like diabetes, hypertension, parkinson and Alzehmier disease, so give perfect opinions in these cases.
i think the methods used to detect the septicemia and bacteriemia is critical and need a professional Technic . isn't it?
I am trying to develop a study abroad class in Havana, Cuba, for my undergraduate Exercise Science & Wellness students. I think it would be a great way to expose them to a very different way of assessing and training athletes, general population and people with chronic disease. Does anybody know who might be willing to host a 2-week long course of about 8-12 students?
in our society a lot of people with chronic diseased use herbal medicine in the course of treatment
Assessment of Health- related quality of life (HRQoL) is an important measure of the individual well being especially those with chronic diseases like thalassemia. However, there few studies about the HRQoL of pediatric patients with non transfusion dependent thalassemia, specifically those with hemoglobin H disease.
I would be grateful if you can share with me such studies or references.
I recently completed a scoping review of interventions for community-dwelling persons living with dementia and would be glad to share these results with your team and connect further.
I am preparing my thesis on the knowledge gap in primary care in the the diagnosis and treatment of obesity and the metabolic syndrome as a chronic disease. I intend to provide an educational intervention to primary care practitioners and need a tool to determine if the intervention was effective.
e.g. I am collecting data from patients suffered from chronic diseases. The objectives are to estimate the prevalence, and to identify factors associated with the chronic disease.
I am writing my masters capstone paper on the effects of chronic disease/disability on adult learners' desire to engage in or persist in adult education experiences (distance and F2F programs). I hope to find reference to significant contributors or research related to this idea.
As this is the era of new emerging technological mobile applications and/or softwares but much of the peoples do not know these and working of these, so it is better time to apply latest information for better control of obesity and diabetes. Many companies are building new artificial intelligence for detecting obesity, diabetes and hypertension, so for tackling these chronic diseases, we have to be ready for futuristic thinking for diagnosis, management and treatment of all these diseases. Thanks all for sharing and participating in questions and answers. it is not for me but for all humanity to save their lives.
I am looking at a longitudinal study of two ethnic populations. they were first seen/recruited at time T1. The total number of participants was 30k. out of these 15k were then followed up at T2. however this T2 is not same for all participants, like some participants were seen after 5 years, some after 6, some after 7 and so on. My aim is to look at the progression of chronic disease in these two populations and compare the results. I want to conduct survival anaylsis but because of the variable follow-up time I don't know how to proceed.
Can you please help me understand how to apply the tools for survival analysis and cox regression in this case?/
Iam searching about data-set irises images of any chronic diseased persons to use it in the iridology field ,,any one can help me??
Hi. I am unable to find an English copy of the “German
health and illness related control beliefs questionnaire". Could someone please suggest where to find it. Also, I am administering the questionnaire to chronic disease patients so to determine their health control orientation, would you suggest that I use “German
health and illness related control beliefs questionnaire", or The Multidimensional HLOC Scale? Thank you
Does clenching jaw associated with age, face exercise with open mouth, using heavy shaver, psychological state? which jaw is more affected right or left?
What is the treatment suggested? you may also suggest physical state of food, certain foods that may help, messaging, cold or hot pads...etc
Sugar and/or fructose is very commonly found in drinks and other beverages, which is utilized from much of the populations in the world, so what are its beneficial and what should be done for its guidance to stop different chronic diseases like diabetes.
I've been presented with a case of a woman who is chronically tired at sea level, where she lives, where she is in a state of not being able to walk for 5 min at a speed of 1 km/h. It is only when she is at altitude (>1500 m) that she regains strength and endurance within hours and is able to walk at a normal speed, with frequent breaks, due to a lack of endurance power, probably caused by being unwillingly sedentary at home. Regular hospital doctors and specialists haven't got any idea what it could be.She found out by herself that the use of an altitude tent a couple of hours per day relieves inablity to be active to some extent.
It seems as it also genetic, as the children of her sister have the same symptoms.
What can cause this disease? Is there a name for it? It seems to me that an increase in the Hypoxible Inducable Factor seems to have a positive effect on her.
The most common chronic diseases and causes of death of our current population (e.g. cardiovascular diseases, cancer) are usually explained by the longer lifetime, and that during the evolution human body was not shaped to live that long, and therefor the body naturally degrades by time.
However, some found that hunther-gatherer tribes, and possibly our anchestors live as long as 70 years (Gurven & Kaplan, 2007).
Thus, to which amount chronic diseases are caused by (1) 'time passing' and a body not designed to live that long or (2) the maladaptive features of our lifestyle?
Im against it in 90% of the cases, many questions comes to my mind in their regards, of which, what are the sources of these protiens?, how safe are they?
Many people are replacing food by protuen shakes, and as we know as maximum our diet must be composed 25% of protiens, some are consuming 40% due to these shakes, I wonder the extant of damage there kidneys would suffer from and other organs.
Protien shakes or powders can be a complimentary for the diet of an athelete if taken in proper amounts after body composition analysis, and if theur source is safe and healthy, be it plants.
I need satisfying answers.
Is there a research that explore the efficacy of step test and breathing exercise as part of cardiac rehab program?
I am looking for a standardised way to describe neurological sequelae in children after e.g. encephalitis when performing a retrospective review of Medical files.
Our study explores the diversity of microorganisms thriving on common surfaces found in the gym setting. Our body's normal processes such as breathing is much different from when at rest as compared to when we are active in sports or exercise and we are wondering if this could play a part in perhaps increasing one's vulnerability to infections.
I theorize that intraorally adherent dental probiotics may improve dental health and overall health by eliminating morning breath.
Plenty of evidence exists supporting some efficacy of dental probiotics to reduce periodontal inflammation -- which is one of the portals of the oral/systemic link.
However, none of the research has been done on a dental probiotic that can last 8 hours intraorally.
I have observational evidence of periodontal improvement with an adherent dental probiotic lozenge.
The study is on health-related quality of life of women living with HIV in an African setting Please assist with information on the recent valid instrument.
Research topic is "level of awareness about Rota-virus among mothers and care taker".
i need a questionnaire to check the awareness of rotavrius among mothers and care taker?
Is There any large sample clinical studies on the effect of Mudras (a type of Yoga Therapy) in various diseases?
As a therapist at MMH and LCCH in Brisbane this is one of our major client populations. We would be very keen to stay apprised of how this project progresses.
I'm interested in learning about what happens to people when many of their physical capabilities and stamina, strength are compromised by severe illness, an accident, or mental illness. What makes it possible for people to move on and become productive and involved in life .... reinvent themselves when they lose many capabilities that they used to have?
I'm looking for a few or several articles relevant to what I'm interested in and/or the names of several health care professionals or academics who are active in this are of research. I would call it overcoming disability or rediscovering oneself and our skills in a area that can make use of our minds and intellectual skills.
Here's an essay I just wrote about what I have experienced over the last eleven years:
How I Learned To Forgive And Live Again Writing On Google Plus
By Frank Elliott January 15, 2017
I've became more and more interested in the practice of forgiveness over the past eleven years because several severe chronic illnesses had combined their strengths to overwhelm my way of life. I had been very strong, a gifted person in terms of my eye-hand coordination and reflex speed and academic skills, but became housebound with terrible burning pain. It took constant work and cooperation with seven or eight medical specialists to even stabilize my conditions. I was mad, felt persecuted, and each day of existence was like a long, drawn-out execution. My intense anger and emotional outbursts about how life had so cursed me became the sum of my self-talk. I realized after living this way for a couple of years that I would need to learn to forgive myself and my diseases to move on. The last 9 years has been a story of learning to forgive and live peacefully. Gradually, I picked up my old love of writing and my fury turned toward concentrating on describing the world around me and in me so that other people could learn to understand themselves too. If I can learn to forgive and live in peace and reach out in love and kindness, so can many, many others. To do that I had to let go of all the imagined wrongs and the hate, the fury. The concentration on describing the world of science, nature, physics, astronomy, and developments in the fields of medicine and health care gave me an outlet to the world around me through Google Plus and let the love of others in.
Gradually, but slowly at first, many people let me into their lives and I let them into mine. People began to love what I wrote of and how I had become so upbeat and positive. I began to love myself too because of them. Gradually I had become a miraculous new being of light. I would have never imagined that eleven years before. I've had to slow down and stop my writing and sharing sometimes for many months at a time, but I always start up again when the storm of symptoms subsides or I find a way around it, over it, or under it. I've given myself that permission to rest and attend to my needs and restore my health.
I can accept my own weaknesses and frailty now. I could never do that before. Severe illness was able to give me many gifts and open many new doors because I learned to slow down, listen to my body, and get help as well as take actions designed to mend myself. I don't know if I could have learned this or many other lessons that changed my life either if I had not learned to listen. The truth is that I was forced into it. I was not about me but about a kind of grace. Life has a kind of grace that invites us to come in and change and learn more deeply about who we are. I've found we only need to pick up the call and listen. To me this means heading down the long road of peace building within myself and with others too.
By Frank Elliott about my interest in the Google Plus social networking site. My Google Plus commentary and posts can be found at this address: https://plus.google.com/108713721375842222592/posts
Those who treat patients with glaucoma, know that many patients that are on glaucoma treatment, really don`t have glaucoma. As in many other chronic diseases, overdiagnosis and overtreatment are big problems in glaucoma. Nevertheless very few publications have addressed this issue.
Which strategies should be implemented to reduce the problem of overdiagnosis in glaucoma?
Since the dawn of IV TPN insulin has been added to the formula as needed to keep the blood glucose below 200 gm%. This is renal threshold. The aim is to prevent glucosuria and associated osmolar dehydration. An objection was that 17% of the insulin adheres to the glass. Since what adheres is immediate, this makes no difference re clinical efficacy. An estimate of how much insulin should be added is 5 U regular insulin per glucose + in the urine. i.e., 2 + glucosuria requires the addition of 10 more unites to the formula.
Ignoring glucosuria will lead to hyperosmolar nonketoic dehydration and potentially death. Prolonged hyperglycemia will predispose the patient to fungal infection.
Is a high basal sympathetic nervous system activity a predictor of short life- span in humans?
I'm hoping to find a source of data that goes back before the 1940's and I would be delighted to learn that there are places to look more for international statistics, or comparisons,even, by country. What sort of data are available? I'm especially looking for data on diseases such as diabetes, heart disease, cancer, autoimmune disease and neurodegenerative diseases like Alzheimers and Parkinson's disease. Does anyone know of some good resources? Many thanks!
There are several articles equating Periodontal Disease to an infection. There are several articles showing the relationship of infections on chronic diseases. Is it possible to cure the infection and eradicate the disease? Can it be that simple? I am building my research project around this question. The relationship between preventable infections and chronic diseases. My question to you: What are your thoughts, experiences, and observances with infections and their impact on health?
Sandy Evans, MHA
Others have provided compelling evidence that schizophrenia, like many chronic diseases, may in part be due to mitochondrial dysfunction. As a clinician, I am aware of the use of R-lipoic acid, L-carnitine or acetylcarnitine, CoQ10, N-acetylcysteine, omega-3 fatty acids, and other mitochondrial nutrients and antioxidants in treating persons with schizophrenia. But I am still unclear (as I suspect is everyone else) re: optimal dosing, which antioxidants/mitochondrial nutrients to use, etc....although I do believe multiple agents are needed.
Anything that would help me clarify my thinking will be much appreciated.
Chronic diseases need nursing practice for a long time. On the other hands, there are many theories of nursing for a better client care.Which of nursing theories is more useful for nursing of chronic diseases as a long time necessity?
Brain perfusion, as referred in this article, includes delivery of nutrients and removal of wastes, besides the usual non-stop gas transfer. From my observations on REM sleep (or the deprivation of REM sleep to be exact) and taichi (the extra slow moving type which can trick the brain that he/she is not moving to simulate REM sleep), I could only say that brain perfusion happens probably not more than 30 minutes for a 7-hour good sleep. For city folks who are under constant stress, they will get less because they would have less REM sleep. During day time, the situation gets worse if they don’t do enough short walks or equivalent exercises (Note: endurance exercises are not counted at all). I believe that many chronic diseases including Alzheimer’s, HIV, cancers, etc. would be difficult to heal once the patients become immobile and/or cannot sleep well. Their brain cells would deteriorate slowly due to malnutrition and waste accumulation. Downstream organs will also be affected slowly one by one.