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Cellular Structures - Science topic

Components of a cell.
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Publications related to Cellular Structures (10,000)
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Tumor vaccination is a promising approach for tumor immunotherapy because it presents high specificity and few side effects. However, tumor vaccines that contain only a single tumor antigen can allow immune system evasion by tumor variants. Tumor antigens are complex and heterogeneous, and identifying a single antigen that is uniformly expressed by...
Article
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This paper studies the snap-back of the buckled triangular structure, which consists of three clamped-clamped elasticas. Here the rotation control is applied at one vertex, where the slopes of two clamped-clamped elasticas at the vertex are controlled. The deformation of the buckled triangular structure is obtained by the stiffness-curvature curves...
Article
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The probiotic bacterial strain Enterococcus faecium SF68 has been shown to alleviate symptoms of intestinal inflammation in human clinical trials and animal feed supplementation studies. To identify factors involved in immunomodulatory effects on host cells, E. faecium SF68 and other commensal and clinical Enterococcus isolates were screened using...
Article
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Intellectual and Developmental Disabilities (IDDs), such as Down syndrome, Fragile X syndrome, Rett syndrome, and autism spectrum disorder, usually manifest at birth or early childhood. IDDs are characterized by significant impairment in intellectual and adaptive functioning, and both genetic and environmental factors underpin IDD biology. Molecula...
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Chronic inflammation is currently considered as a molecular basis of metabolic syndrome. Particularly, obesity-induced inflammation in adipose tissue is the origin of chronic inflammation of metabolic syndrome. Adipose tissue contains not only mature adipocytes with large lipid droplets, but also a variety of stromal cells including adipocyte precu...
Article
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Hydrogen, as a clean energy carrier, is of great potential to be an alternative fuel in the future. Proton exchange membrane (PEM) water electrolysis is hailed as the most desired technology for high purity hydrogen production and self-consistent with volatility of renewable energies, has ignited much attention in the past decades based on the high...
Article
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Purpose Bifidobacterium is an important probiotic used in food and medicine production. The probiotic properties of bifidobacteria are strain specific, so it is necessary to evaluate the probiotic properties of bifidobacteria isolated from specific populations, especially when developing products suitable for specific populations. The objective of...
Article
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In recent years, extracellular vesicles (EVs)¹ have attracted attention as a new therapeutic tool. In Europe, the United States, and Asia, there is an accelerating trend of moving beyond basic research on clinical trials. However, treatment using EVs is still in the research and development stage, and the general public has insufficient awareness a...
Article
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Cellular structures are increasingly used in practical engineering due to their excellent physical properties, such as lightweight, high strength, impact resistance, and high ductility. In this work, a data-driven topology optimization method is developed for the steady-state heat conduction problem of cellular structures with multiple microstructu...
Article
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Background Periodontitis is an infectious disease, and a risk factor for peri-implantitis that could result in the implant loss. DNA methylation has an essential role in the etiology and pathogenesis of inflammatory disease. However, there is lack of study on methylation status of genes in periodontitis. This study sought to explore the gene methyl...
Article
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Upon infection, viruses hijack the cell machinery and remodel host cell structures to utilize them for viral proliferation. Since viruses are about a thousand times smaller than their host cells, imaging virus-host interactions at high spatial resolution is like looking for a needle in a haystack. Scouting gross cellular changes with fluorescent mi...
Article
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Background: Breast cancer is the most common cancer in women and the leading cause of female cancer deaths worldwide. Obesity causes chronic inflammation and is a risk factor for post-menopausal breast cancer and poor prognosis. Obesity triggers increased infiltration of macrophages into adipose tissue, yet little research has focused on the effect...
Article
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Background Lactic acid, as a product of glycolysis, increases tumor cell migration and the invasion of tumor cells in the tumor microenvironment. Besides this, lactic acid promotes the expression of programmed death-1 expression (PD-1) in regulatory T cells, which could cause the failure of PD-1 blockade therapy. However, the implications of lactic...
Article
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Foamed Polymer is an important polymer material, which is one of the most widely used polymer materials and plays a very important role in the polymer industry. In this work, foamed polypropylene (PP) composites are prepared by injection molding, and the cell deformation process within them is studied by combining visualization technology and COMSO...
Article
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Milkfish (Chanos chanos) is an abundant fish commodity in the Philippines that generates a large number of wastes such as skin, scales, viscera, and bones, which, upon disposal, cause environmental pollution. The abundance of these wastes, such as fish skin, rich in bioactive natural products such as collagen, elicits interest in their conversion i...
Article
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Understanding the chemical composition and morphological evolution of the solid electrolyte interphase (SEI) formed at the interface between the lithium metal electrode and an inorganic solid-state electrolyte is crucial for developing reliable all-solid-state lithium batteries. To better understand the interaction between these cell components, we...
Preprint
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Unambiguous targeting of cellular structures for in situ cryo-electron microscopy in the heterogeneous, dense, and compacted environment of the cytoplasm remains challenging. Here we have developed a novel cryogenic correlative light and electron microscopy (cryo-CLEM) workflow which combines thin cells grown on a mechanically defined substratum to...
Article
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The production of raw natural rubber always ends up with leftover latex. This latex is later collected to produce low grades of rubber. The collection of this latex also depends on the latex’s quality. However, reproducing the latex may not be applicable if the latex contains many specks of dirt which will eventually be discarded. In this work, an...
Article
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Sandwich panels have a wide field of applications from aerospace to automotive industries. These panels are formed by a core and two layers, having the geometry of the core an important role in its mechanical properties. While the most common cores have hexagonal honeycomb structures, there is a recent trend to replace them with other cellular stru...
Article
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The concept of “lockyballs” or interlockable mini-scaffolds fabricated by two-photon polymerization from biodegradable polymers for the encagement of tissue spheroids and their delivery into the desired location in the human body has been recently introduced. In order to improve control of delivery, positioning, and assembly of mini-scaffolds with...
Article
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Laser powder bed fusion (LPBF) is an emerging technique for the fabrication of triply periodic minimal surface (TPMS) structures in metals. In this work, different TPMS structures such as Diamond, Gyroid, Primitive, Neovius, and Fisher–Koch S with graded relative densities are fabricated from 316L steel using LPBF. The graded TPMS samples are subje...
Chapter
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Oxidative stress is the consequence of an imbalance between pro-oxidant and antioxidant processes. The intensive exercise increases circulating radical oxygen species levels in mammalians. Horse is a useful model to study the relationship between physical performances and related structural and metabolic derangements. Erythrocyte membranes are dama...
Article
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Focal adhesions (FAs) are the main cellular structures to link the intracellular cytoskeleton to the extracellular matrix. FAs mediate cell adhesion, are important for cell migration and are involved in many (patho)-physiological processes. Here we examined FAs and their associated actin fibres using correlative fluorescence and scanning electron m...
Article
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The use of cellular structures has led to unprecedented outcomes in various fields involving optical and mechanical cloaking, negative thermal expansion, and a negative Poisson’s ratio. The unique characteristics of periodic cellular structures primarily originate from the interconnectivity, periodicity, and unique design of the unit cells. However...
Preprint
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In an earlier work, we defined a ``generalised Temperley-Lieb algebra'' $TL_{r,1,n}$ corresponding to the imprimitive reflection group $G(r,1,n)$ as a quotient of the cyclotomic Hecke algebra. In this work we introduce the generalised Temperley-Lieb algebra $TL_{r,p,n}$ which corresponds to the complex reflection group $G(r,p,n)$. Our definition id...
Article
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The chemical desorption of arsenic from saturated iron-coated cork granulates (ICG) and the regeneration capacity of this adsorbent for further reuse was investigated in batch and continuous modes. Different types of eluents were tested at different concentrations for evaluating their desorption capacity, and leaching of total organic carbon (TOC),...
Article
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Efficient HIV-1 replication depends on balanced levels of host cell components including cellular splicing factors as the family of serine/arginine-rich splicing factors (SRSF, 1–10). Type I interferons (IFN-I) play a crucial role in the innate immunity against HIV-1 by inducing the expression of IFN-stimulated genes (ISGs) including potent host re...
Preprint
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The purpose of this paper is trifold -- to serve as an instructive resource and a reference catalog for biologically plausible modeling with i) conductance-based models, coupled with ii) strength-varying slow synapse models, culminating in iii) two canonical pair-wise rhythm-generating networks. We document the properties of basic network component...
Article
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The Sertoli cell tumor of the ovary is a rare ovarian tumor with non-specific symptoms. According to the literature, endocrine manifestations occur in two-thirds of patients, but testosterone production is extremely rare. Typically, it is a unilateral benign tumor of the ovary that most commonly presents in adolescents and young women of childbeari...
Preprint
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The present work reports new experiments of detonation diffraction in a 2D channel configuration in stoichiometric mixtures of ethylene, ethane, and methane with oxygen as oxidizer. The flow field details are obtained using high-speed schlieren near the critical conditions of diffraction. The critical initial pressure for successful diffraction is...
Article
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A designer of metallic energy absorption structures using additively manufactured cellular materials must address the question of which of a multitude of cell shapes to select from, the majority of which are classified as either honeycomb, beam-lattice, or Triply Periodic Minimal Surface (TPMS) structures. Furthermore, there is more than one criter...
Preprint
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Cancer is a large group of diseases that exert heterogeneity individually, which resulted in the various lifetime individually and the specific response to anti-cancer drugs. Classification of patients as the prognostics is thereafter the key point for drug selection and therapeutic effect. Adenosine pathway which hydrolyzes extracellular ATP into...
Article
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Interspecfic competition between corals and macroalgae is a common phenomenon on coral reefs, and its impacts on the cellular structure of corals are not well studied. Field observations in Gulf of Mannar Marine National Park (GoM), a protected reef environment, during January 2020 revealed abundant growth of the macroalga Turbinaria conoides over...
Preprint
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Cancer is one of the leading causes of death worldwide. Reactive oxygen species induce pathology by damaging lipids, proteins, and DNA. Elevated reactive oxygen species levels, accompanied with down-regulation of cellular antioxidant enzyme systems, result in malignant transformation. Potassium bromate is a chemical oxidizing agent that is a famous...
Article
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The anti-collision pier plays an irreplaceable role in road traffic protection due to its significance. In this research, the biomimetic honeycomb structure was applied to internal anti-collision pier interior structures. The enhancement of mechanical strength and energy absorption characteristics was explored and optimized by five anti-collision p...
Article
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The early stages of the virus–cell interaction have long evaded observation by existing microscopy methods due to the rapid diffusion of virions in the extracellular space and the large three-dimensional cellular structures involved. Here we present an active-feedback single-particle tracking method with simultaneous volumetric imaging of the live...
Article
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The influence of an external constant strong electric field, formed using a pyramidal structure under a high electric potential, on an enzyme located near its apex, is studied. Horseradish peroxidase (HRP) is used as a model. In our experiments, a 27 kV direct current (DC) voltage was applied to two electrodes with a conducting pyramidal structure...
Article
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In 2021, the electric vehicles (EVs) market reached a record-breaking 6.5 million vehicles, and it will continuously grow to USD 31 million in 2030. However, the risk of battery damage should be reduced using a lightweight crashworthy protection system, which can be performed through design optimization to achieve maximum Specific Energy Absorption...
Conference Paper
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Within a circular economy framework, recycling concepts for solid-state batteries (SSBs) need to be developed before widespread application to ensure sustainable production. A promising oxide-based solid-state electrolyte (SSE) is garnet-type Li7La3Zr2O12 (LLZO), which possesses a high ionic conductivity, a wide electrochemical window, and good sta...
Article
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Neurodegenerative diseases represent a large group of disorders characterized by gradual loss of neurons and functions of the central nervous systems. Their course is usually severe, leading to high morbidity and subsequent inability of patients to independent functioning. Vast majority of neurodegenerative diseases is currently untreatable, and on...
Article
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In this paper, the vibroacoustic performance of the star-shaped honeycomb-core annular cellular structures is investigated. The results imply the superiority of these structures over the hexagonal honeycomb-core annular cellular structures, with constant mass and overall structure size, in terms of sound insulation relative to static bending compli...
Article
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Nasopharyngeal carcinoma (NPC), as a malignant tumor, has increasingly affected the health and survival of human, and certain changes in the phosphorylation level of protein have been found in the serum of NPC patients. Thus, the investigation of phosphoproteins/phosphopeptides in human serum of NPC patient will conduce the understanding of the rel...
Article
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In this work, the foaming process of poly(vinyl alcohol) (PVA)-Gelatin (Gel)/Carbon nanotube (CNT) composites in a high-pressure batch foaming technique using supercritical carbon dioxide (scCO2) was investigated. The foamability of PVA as a semi-crystalline biopolymer was significantly improved after adding the gelatin content as a plasticizer and...
Article
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. It is known that the quality of a concrete composite, especially a cellular one, largely depends not only on the properties of the original raw materials but also on many technological factors, which are often decisive. In particular, this is relevant when forming a cellular structure. This article discusses the influence of various methods of pr...
Article
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This article presents an examination of silicone, Bouligand lattices in compression. Appearing frequently in biological organisms and manufacturing design, Bouligand structures comprise layers of parallel strands or fibers oriented in a helical fashion. They can exhibit exceptional fracture resistance when composed of rigid or composite materials....
Article
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G-quadruplexes (GQs) have become valid targets for anticancer studies in recent decades due to their multifaceted biological function. Herewith, we aim to quantify interactions of potential heterocyclic ligands (Ls) with model GQs. For seven 4-aminoquinazolines and three 2-heteroaryl perimidines, seven of this ten-membered group so far unknown, we...
Article
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This review focuses on the role of magnetic nanoparticles (MNPs), their physicochemical properties, their potential applications, and their association with the consequent toxicological effects in complex biologic systems. These MNPs have generated an accelerated development and research movement in the last two decades. They are solving a large po...
Article
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Fruit ripening and softening are highly complex processes, and there is an interplay and coordination between the metabolic pathways that are involved in the biological processes. In this study, we aimed to elucidate the variation in the characters and possible causes of cell wall materials and morphological structure during apple fruits developmen...
Preprint
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Objective: This study aimed to determine the potential mechanisms through which long noncoding (Lnc) RNA cancer susceptibility candidate 15 (CASC15)affects hepatocellular carcinoma (HCC). Methods: We retrieved HCC RNA-seq and clinical information from the UCSC Xena database. The differential expression (DE) of CASC15 was detected. Overall survival...
Article
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Cancer-associated fibroblasts (CAFs) are the predominant components of the tumor microenvironment (TME) and influence cancer hallmarks, but without systematic investigation on their ubiquitous characteristics across different cancer types. Here, we perform pan-cancer analysis on 226 samples across 10 solid cancer types to profile the TME at single-...
Article
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In this study, polyolefin elastomer (POE) foams were prepared without any curing agent using a single-step foaming technique. The effect of azodicarbonamide (ADC) content as a chemical foaming agent on the foams’ morphology and mechanical properties was studied using scanning electron microscopy (SEM), mechanical properties (tension and compression...
Article
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The p97 ATPase extracts polyubiquitylated proteins from diverse cellular structures in preparation for destruction by the proteasome. p97 functions with Ufd1-Npl4 and a variety of UBA-UBX co-factors, but how p97 complexes assemble on ubiquitylated substrates is unclear. To address this, we investigated how p97 disassembles the CMG helicase after it...
Article
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High-entropy alloy (HEA) FeCoNiAlTi (FCNAT) systems have been demonstrated to provide high strength while sustaining good ductility, which is of particular interest for the fabrication of structural components with complex geometries. Meanwhile, selective laser melting (SLM) technology that fabricated metallic material using layer-by-layer melting...
Conference Paper
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The purpose of this study was to investigate the feasibility of in-situ foaming in fused filament fabrication (FFF) process. Development of unexpanded filaments loaded with thermally expandable microspheres, TEM is reported as a feedstock for in-situ foam printing. Four different material compositions, i.e., two grades of polylactic acid, PLA, and...
Article
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The concept of “Industry 4.0” encourages the use of automated manufacturing processes and the use of advanced technological systems. Some of the most fundamental needs of the Fourth Industrial Revolution can only be met with the help of additive manufacturing. However, the mechanical behavior and reliability of additive-manufactured components are...