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Cascade - Science topic
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Questions related to Cascade
Can flood paths be identified in mountainous areas? What is the solution? And what solutions can be offered to prevent flooding in human settlements in cities and villages?
like incessant rain, increased hydrostatic pressure, and rapid ice melt, a large amount of lake water can be suddenly released. This leads to dam instability and eventual breach, triggering a GLOF (number . Similarly, LLOFs also involve breaching dams. However, LLOFs dams are formed by earthquakes or rainfall-induced landslides blocking streams and rivers. The landslide carries soil, debris, and other materials blocking streams and rivers to form landslide dams .which in turn create dammed lakes. Rising lake levels and erosion of the dam’s sidewall can destabilize its structural integrity. If the dam fails, it can suddenly release large volumes of water downstream, triggering an LLOF (number .Overall, climate conditions interact with cryospheric and geological environments, collectively driving the occurrence and development of GLOFs and LLOFs. Y. Bai et al. Science Bulletin Our analysis shows that humans and infrastructure in HMA have been exposed to increased risk from various floods in the past seven decades. PFs have the broadest impact, causing at least 23,900 deaths and displacing 105 million people from 1950 to 2023. The PFs triggered by monsoon rains are particularly concerning due to their widespread impact, prolonged duration, and tendency to cause severe casualties and displacements (Fig. S11 online). Additionally, our statistical analysis reveals a significant positive correlation between the number of fatalities and rainfall intensity . Unlike PFs, SFs often mobilize large ice blocks and meltwater, potentially transforming or cascading into debris flows and landslides. On average, each SF in HMA has caused 18 fatalities, affected approximately 128,000 people, damaged 3,378 ha of crops and killed 553 livestock . GLOFs on the other hand have far-reaching impacts, also causing devastating damage to settlements and infrastructure downstream. For instance, over 6,000 fatalities were reported in June 2013 due to the Chorabari glacial lake outburst in the western Himalayas . Like GLOFs, when LLOFs occur, they release a huge volume of water, generating extremely high peak flows and catastrophic floods. Meanwhile, we observe a marked population growth and expansion of infrastructure (e.g., hydropower, buildings, and transportation) in HMA (Fig. S13 online), with an average annual growth rate of 1.53% and 7.11%, respectively. This growth trend is expected to continue under various socio-economic development scenarios .and the exposure to flood risks may further intensify in the future. Besides their direct impact on population and infrastructure, floods can trigger a series of environmental issues and landscape instabilities . Very extreme floods can transport large amounts of sediment and pollutants which could accumulate in downstream river channels and floodplains. These pose serious threats to human health and environmental safety and even delay postflood recovery efforts. For instance, in 1975, spring SFs in Xinjiang, China, washed a large amount of sediment into channels, resulting in 70,000 m3 of sediment accumulation and delaying channel discharge for several months (Fid16 in Table S2 online). Extreme floods can also alter river morphology, resulting in riverbed elevation changes, channel widening, or even river avulsion . For instance, such processes were observed when the Kosi River was flooding in 2008. . Additionally, floods may transport long buried soil organic carbon .and mercury, affecting the regional carbon cycle and drinking water quality. Our state-of-the-art flood inventory is comprehensively compiled from public databases, flood yearbooks, media reports, and literature, and highlights the changes of flood complexity over the past seven decades. We highlight the flood complexity and increasing flood exposure risks due to the growth of infrastructure and population in HMA. The complex trends in flooding frequency arise from the interplay between climate warming, shifted precipitation patterns, rapid melting of glaciers, snow cover, and permafrost, as well as more research and public attention (Supplementary Text S6 online). In a warming future accompanied by accelerating glacier melting, snowfall-rainfall shift, more frequent rainfall extremes, and growing human activities, flooding risk in HMA is expected to further increase without effective adaptive measures. We emphasize that identifying risk-sensitive areas and adjusting the spatial distribution of population and socio-economic activities are essential in the future. Additionally, international data sharing and encouraging indigenous people, especially the youth, to participate in local flood mitigation efforts are vital for creating further awareness and addressing climate challenges in HMA.
I am one of the Authers and I am not allowed to add my name
Hi, I have established a bioreactor parameters mammalian cell process with the following parameters:
Setpoint Deadband PID settings
1) pH- 7.0 0.1 1.0,5.0,1.0
2) DO- 60% 1 1.0,1.0,1.0
3) Stirer- 127 0
4) PO2 cascade with oxygen at (10ml/min)
5) pH cascade with base and (acid CO2 at 10ml/min)
The issue here is still the oxygen doesn't stop at the given setpoint and reaches around 120-180 % DO.
what can I do to maintain the DO to the specific setpoint. The total volume of reactor is 250ml and WV is 100ml.
The other issue here is the stirrer speed at what rpm I should be keeping it. Can we calculate the rpm of the stirrer according to the volume of the working volume of the reactor. Tip speed was calculated as- 0.0376m/s.
please let me know if more information are needed.
Hi,
I am new to research in the field of medicine. What would be the best way or method to find the prescribing cascade ? Should I have excel file and check it against the patient pharmacy record ?
We've got a problem with OD600 after overnight growth in bioreactor namely after
12 h we've reached 8 ,
7 and 6 during three day respectively . We want to establish DO cascade by means of glucose dosage by pump , but maybe this is wrong solution we've no enough experience in this subject ( maybe 'll be better we have to set up pH in cascade instead of DO )
Thank you for your suggestions
We've got a problem with OD600 after overnight growth in bioreactor namely after
12 h we've reached 8 ,
7 and 6 during three day respectively . We want to establish DO cascade by means of glucose dosage by pump , but maybe this is wrong solution we've no enoug experience in this subject ( maybe 'll be better we have to set up ph in cascade instead of DO )
Thank you for your suggestions
The topics should have to do with two or more induction motors cascaded and be used as drives.
I would like to ask for small help regarding the Automation/Robotics of hand manufacturing prism solution.



Does anyone have an example of a parasite species where the non-parasitic life stage(s) hold a key location in the ecosystem, not related to the host, where elimination of the parasite could cause an ecological cascade?
I know that, theoretically, elimination of a parasite might cause a host population to increase unchecked, which in turn could have cascading effects on other trophic levels, competitors of the host, etc. And there might actually be real-world examples of this.
BUT, what I am looking for is an example where elimination of the parasite causes an unrelated cascading effect (for example, if elimination of screwworms (Diptera: Calliphoridae) might cause a plant species to decline because adult screwworms were no longer present to pollinate the plants.)
The only example I've seen so far is Wyeomyia smithii mosquitoes in North American pitcher plants. They function as a key member of the tiny, close-knit intra-pitcher plant community, where they feed on organic detritus left by the Metriocnemus knabi midges, making nitrogen available to the plants. But there are also many other microorganisms (rotifers, bacteria, protozoa) present that could potentially fill the niche left if Wyeomyia were eliminated. Plus, Wyeomyia adults are only facultatively parasitic.
There was a problem with gel electrophoresis. I don't really understand what's going on. Every time I act according to the protocol, but every time it turns out to no avail. I need a hint. Chemically synthesized single-stranded DNA is used for quantitative determination. I use 2% agar per 100 ml of TAE buffer (1x) with the addition of 10 µl of ethidium bromide. I prepare samples in a ratio of 1:1 each. Сell C contains DNA labeled with TAMRA fluorophore with 60% glycerin. In the D cell - DNA (Dz1e) with a size of 30 b.p. In the cell E, a mixture of TAMRA-DNA and Dz1e - in theory, there should be 46 p.o. In cells F and G, a mixture of several DNA samples of sizes 88 and 231 b.p., respectively. The voltage in the system was 60V. The samples were run for 1 hour. 6x loading Dye was used as a buffer for samples. But unfortunately, looking at the picture, it is hardly possible to identify the resulting DNA cascades. Who can tell you how to change the conditions

The Mandelbrot set is related to the Feigenbaum cascades, which are found in lots of mathematical models of real-life phenomena. But does the Mandelbrot set have have any real-world use, either on its own or in connection with Feigenbaum cascades? Or is it purely aesthetic?
Diabetes is a multifactorial disease characterised by chronic hyperglycemia as the baseline symptom. However, specific dietary components have been implicated as classic independent risk factors. Scientific investigations of these on-switches with respect to the pathogenesis of types I and II diabetes is very vital in preventive clinical practice. What is the distinguished "nutritional sword of Damocles" that usually precipitate insulin deficiency/pancreatic beta cell destruction as well as insulin resistance? How do these dietary agents instigate molecular cascades to initiate and also sustain lifelong hyperglycemia?
Different cascaded fiber structures such as single-multi-single (SMS) mode, multi-single-multi (MSM) etc. have unique spectral features due to the multimode interference (MMI) phenomena. The transmission spectrum depends on the sensing fiber length i.e., SMF and MMF for MSM and SMS, respectively at the time of fabrication (ignoring the effect of external perturbations).
How does the group dispersion phenomenon affect these spectral features?
The spectrum of one of such cascaded fiber structures (here MSM) has been attached for the reference that occurs due to the MMI phenomena.
#fiber #SMS #MSM #Groupdispersion #opticalfiber
Pls provide some relevant research paper for reference.
Fs=?; %Sampling frequency ?KHz
Flp=?;
Fls=?0;
Wp=2*Flp/Fs;
Ws=2*Fls/Fs;
Rp=?; %(unit:dB)
Rs=?; %(unit:dB)
[N,Wn]=cheb1ord(Wp,Ws,Rp,Rs);
[b,a]=cheby1(N,Rp,Wn); %
[hw,w]=freqz(b,a);
subplot(2,1,1);
plot(w/pi,20*log10(abs(hw)));grid on;
xlabel('ω/π');ylabel('amplitude(dB)')
title('BM filter');
subplot(2,1,2);plot(w/pi,abs(hw));
grid on;
xlabel('ω/π');ylabel('amplitude(H)');
This is for matlab use.
Can you please give me some advice on this?
I knew that The basement membrane model consists of 108 or 54 second-order low-pass filters cascaded in decreasing order of cut-off frequency.
Just wanna a simple model of cochlear.
Hello,
I have been trying to research to develop a cascade CS CS Low noise amplifier on keysight ADS. I haven't been able to find a direct reference for such LNA.
I would appreciate your assistance
Thank you
So this really is a discussion about something I am just curious about: should we redefine the oxygenation target in COVID0-19 patients, and aim to individualize it instead?
Current guidelines recommend a target SpO2 of 90-96%. Improved oxygenation has been linked with avoidance of a hypoxia stimulated inflammatory cascade.
I am going to link a few studies down here as well which discuss this oxygenation criteria in more detail.
Personally, however, I have this lingering afterthought that baseline oxygen saturation of patients should be used as a guide for determining target goal for oxygenation. A setpoint can be researched and identified, and we can aim for a goal of 20-30 %, or even 50% greater target saturation than baseline saturation in COVID-19 patients. This might potentially mean that we aim for a lower PaO2, using a more conservative approach towards oxygenation, and focusing more on correcting underlying pathology than simply driving loads of oxygen in decompensating lungs. There is a clinical trial currently going on as well about conservative versus aggressive oxygenation in COVID patients (https://clinicaltrials.gov/ct2/show/NCT04425031)
I have no idea if this notion is correct or not. Nor have I tried it on any patients in clinical practice because there is no proper clinical trial protocol that I have for this. But I am just interested hypothetically in how this works, and if maybe it makes sense.
If anyone has any experience/advice/literature/thoughts to share on this, please do!
Here are some interesting articles on this too:
3. HOT-COVID: https://clinicaltrials.gov/ct2/show/NCT04425031
I have a molecule which according to my kinase data analysis activates several putative pathways. Is there a way to visualize these e.g. the RAGE, VEGFR2, TCR, TLR (and others) signalling cascades and showing their overlap and interaction? I would like to find common parts of these cascades to identify the "core" affected signalling pathways.
Thanks in advance!
Cheers,
Niko
Comprehensive ground water management requires suitable tools that consider the groundwater balance as well as the variety of potential risks that might impact groundwater recharge and chemistry. Due to cascading anthropogenic effects, particularly in urban areas this forms a challenge. Which simulation and management tools (both, freeware or licensed software) do already exist?
dear researchers, having a cluster of islanded DC-Microgrids supplied by PV- Battery- Supercapacitor, besides supported by backup diesel generator, how to control the diesel generator when compensating power unbalace of microgrids? Is it uaing dual loop cascaded structre, or using single current loop control.
Noting that the battery and supercapacitor are controlled with dual loop structrue considering the Dc bus voltage deviations.
Thank you for your reply and feedbacks.
I would highly appreciate if you can comment down below some leading works on ICA in the context of cascading disasters (disasters whose effects spread through space and time).
I prefer numerical modeling works.
Many thanks!
I am looking for some new ideas to cascade these two reactions together. I used glycosidase to catalyze the first transglycosylation and Novozyme 435 to catalyze the esterification reaction.
The problem is the first step reaction needs 10% of water, but, there shouldn't have any water in the second step. Anyone who can provide useful ideas, I will add your name as a coauthor when I publish this work.
When measuring gamma spectra from the decay of a radioactive nucleus, I observe 3 peaks in the spectrum. The databases indicate that during the decay of this nucleus, there are only 2 lines that lie in a cascade. The third observed peak is cumulative and is approximately 10% of the first or second peak. What is the possibility of dividing the third peak into contributions from the first and second transitions?
Hello friends,
I am working on a control strategy of a grid connected 7 Level cascaded H-bridge(CHB) with independent Maximum Power point tracking (MPPT) PV System, according to the enclosed reference papers ( they have nearly the same control strategy).
Each H-bridge is connected to a single PV module with Vmpp= 75V, and Impp= 1.4 A. The PV modules voltages and currents are not getting stable and even they are not changing although I tried to adjust the DC link capacitors and the PI voltage and current controller gains, so I thought maybe there is an issue in the Control strategy implementation. A PLL is used for synchronisation and a Phase shifted PWM (PSPWM) is implemented in this Matlab Simulink model.
Important to notice, that the model and my MPPT algorithm (P&O) is working perfectly fine with a single H-bridge, I also tried to adjust it with 7 level CHB, but no changes in the results.
Is the implementation of the control strategy right? and do you have an idea where can the issue be? I can convert and send you the file if you can help me with this.
Enclosed you find the reference papers, Control strategy scheme and the Simulation results.





+1
For cascade refrigeration system, when we want to calculate the compressor discharge temperature (T2) of lower temperature circuit. İ know it is calculated depending on evaporator temperature of lower temperature circuit. but i dont know how to calculate the compressor discharge temperature (T6) of high temperature circuit. On their articles of some researchers, it seems that they calculated depending on evaporator temperature(T1). İ think it is wrong because of the fact that compressor discharge temperature of high temperature circuit depends on evaporator temperature of high temperature circuit.
Dear Researchers, does anyone know already applied cascaded fuzzy PI-PI (i.e. Fuzzy PI speed controller + Fuzzy PI current controllers) control scheme to regulate speed of Permanent magnet synchronous machines (PMSM)? I could not see any published studies on combined fuzzy PI speed and fuzzy PI current controllers in the web. If any available, could you please share the papers or studies about this issue?
I am designing a 3-stage inverter TIA. The first stage in my design is capable of voltage gain 5x at the maximum(14 dB). I wanted to increase this gain, so I cascaded it with two similar stages. For a first stage alone, the phase margin of the system from stb analysis in cadence is about 96 degree. The three stage cascade on the otherhand has a phase margin of -130 degree indicating unstable system. To tackle this issue, while having the cascade; what is the best way to approach towards bettering my phase margin?
It seems like by varying the feedback capacitor and resistor alone, the phase margin is not improving. So how to get over the low phase margin; any parameters that I need to check/adjust? The figures for the phase and gain (For Phase margin calculation) single stage and 3 stage TIA are attached here.
-Rakesh.

Sir ,
When there is a fault on the lower H-BRIDGE diagonal switches the waveforms of output voltage is similar . How did the neural network model classify the fault in this case ?
I am currently working on prevention of cascading failure using Q-learning in a power network. I don’t have a very good expertise in MATLAB. Could someone please assist me how should I carry out the experiment using SIMULINK?
I have created a three-phase cascaded h-bridge inverter at Simulink with the SHE-PWM technique, and I want to test it in the DVR applications. How can I design a controller for that in the DVR application?
I am working with a two output single input system using a cascaded PI control strategy. But that is not effective in rejecting the disturbances in the system. As a result I was looking at the application of 2dof PID for the outer loop to reject the disturbances and have a better control. Can someone help me with the tuning procedure of this type of PID controller? Also is it that 2dof PID is applicable only for systems with time delay? Please give specific suggestions in this regard.
Hi
This is Ravi. i am trying to create a separation bubble on a flat plate using a contoured upper wall. I want to apply same pressure distribution of a given blade on the flat plate. I have read few paper and they mentioned something like this:
" The shape of the contoured wall is designed using a simple one-dimensional continuity argument to match the pressure distribution measured on the flat plate to that measured on the T106 LP turbine cascade."
It would be helpful if some one tell me the procedure or related derivation.
The simple schematic of the contour wall is attached
Dear all,
I have a basic biology question, but have yet to come across a satisfactory answer.
Many signalling cascades downstream of specific receptors occurs through intermediates such cAMP, which is used across various other specific signalling cascades.
My question is, how does the signal maintain specificity further down-stream if a common intermediate is used? How to signals not get crossed within the cell?
Many thanks,
Sam
As there have been identified numerous tipping points in the climate system that might trigger a domino effect or hidden feedback loops [1], I wonder how much more CO2 we can emmit until the system is beyond human control. Or is it possibly already too late?[2]
The IPCC reports indicate, that the risks and impacts increase a lot between a global mean surface temperature of 1.5°C to 2°C. But they are quite far from a statistically significant CO2 budget calculation of p < 0,05.
Therefore I would like to know how much time we have left for a statistically safe pathway with a CO2 budget that is not based on any 50:50 probabilities.
[1]
RESEARCH ARTICLE
Cascading regime shifts within and across scales
Science 21 Dec 2018:
Vol. 362, Issue 6421, pp. 1379-1383
DOI: 10.1126/science.aat7850
[2]
The Output buffer consists of a source follower cascaded with two CMOS Inverters and uses a self biased CMOS inverter to set the bias current for the source follower and bias point for the two inverters.

Hi everyone,
I hope you are well today,
OK, let me go straight forward, I really like to implement the cascade control technique to stabilize the frequency of the Power system. But I'm having too much problem in the concepts of which combinations of cascade control (PI-PD, PI-PID, etc.,)is suitable for the application and how to tune the parameters of the cascade controller.
So I will be really thankful if you can share me some idead, whether you wrote it or you see them somewhere else.
Thanks a lot,
Sincerely,
Andrew
Control Theory
Optimal Control
Optimal Control Theory
Hi guys,
Can someone guide on how can i create a detector to auto detect both sides of human cheeks from large number of dataset using viola jones? basically my project is on detecting cheeks from sequential image frames from low cost webcam. It is an obligation to use Viola jones here. Preferably using Matlab. Do share your inputs. Thank you in advance.
The use of cascaded neural networks for the reverse design of metamaterials and nanophotons can effectively alleviate the problems caused by one-to-many mapping, but the intermediate layer of the cascaded network is unsupervised learning, and an effective method is needed to limit output range of the intermediate layer.
I have a physical system G=Q*D (composed of 2 systems in cascade). I have created a controller with an LQG controller, but not directly for complete system G. I created 2 LQG controllers, that means, "LQG controller for Q" and "LQG controller for D" and use these controllers in cascade to control the physical system. The problem is the disturbances and noise. The physical system has a "process disturbance : N(0,w) "and "output noise = N(0,v)". My question is:
How I can separate the disturbance and noise for each LQG controller?
Thanks a lot for comments and answers
because all steps need ATP. while prolonging the process, more ATP will be used.
what are the drawbacks of using R744 in cascade refrigeration systems compared to R41?
Cascaded DAB dc dc Converter Circuit Design is Required , I have to simulate that in Matlab
The typical approach to designing flight control systems is to design an inner control loop to stabilize vehicle attitude and angular rates, while an outer loop tracks vehicle position. The reason given for the above is that attitude dynamics is "faster" than the translational dynamics. The theory of time scale separation in dynamic systems seems provides an answer to this question but What is the physical intuition behind this argument? Also, Is it possible to design a controller that does not consist of multiple cascading loops?
In the context of MBSE approaches, how do you use model(s) to replace textual requirements depending on the requirement type considered (functional, non-functional, constrains...)? Including requirements links, cascades, attributes (like rationales, owners...) and their links to V&V.
Thanks a lot for your answers
Best regards
I was simulating a cascade cooling system in HYSYS and when I activated the dynamic mode of HYSYS, even after controlling a few parameters(to not change much and remain the same as in static mode) by the PID controller. The other parameters changed by itself and continued to do so till stabilization is reached. I didn't get this result displayed by HYSYS. Did anyone face the same issue?
please sent to me some codes of exergy analysis.(with article)
I have made 2 dumbbell shaped DGS along with T stub and microstrip line but I am not getting correct simulation results
Is it possible to separate dust aerosol from total aerosol to study the optical properties? I would like to quantify the scattering coefficient of dust from different regions. Basically the variation in scattering property when it gets transported, by comparing the samples from source regions and receptor regions. I know we can use cascade impactors to separate particles of different sizes but still, I believe that the dust getting transported will be mixed and of smaller in size. If I collect samples using cascade impactor, what would be the best analysis methods? Thanks in advance.
Agitation was normalized by power input but I am looking to understand how to normalize air sparge, overlay, CO2 cascade settings for pH control and O2 sparge settings for DO control.
Dear All
I am wondering if someone has an good explanation for the "nanobuffering" behavior of pH responsive polymers. Here is some literature on the topic:
In brief, the phenomenon is explained as due to a negatively charged polyelectrolyte attracting protons as counterions, thereby lowering the pH locally in its vicinity. My problem with this explanation is that the concentration of other cations is much higher than that of protons. For instance, the research paper above appears to achieve nanobuffering at a bulk pH of 7 and physiological ionic strength. At pH 7 we have [H+] = 10^-7 M, which is more than 6 orders of magnitude less than the concentration of other cations (Na+, K+ etc). So less than one in a million of the negative charges on the polyelectrolyte will attract a proton, meaning that there couldn't possibly be any significant change in pH (even if we are talking small volumes).
I'm not questioning the results of any published work, just trying to understand what is going on.
how can i support the diode switched multilevel inverter which requires 12 switches with 4 DC sources to produce 27 level with cascaded trinary configuration which uses same 12 switches and 3 DC sources to produce the same amount of 27 levels
I need to employ hysteresis band current control method for the inverter (CHB) used in my STATCOM, however, I am unable to do it.there are several papers within this topic, However they are not well-written or comprehensive. How should I calculate the bands and other characteristic? I need to use this method for a CHB with more than 21 levels.
To design control algorithm for 3 phase inveter with unbalanced load using Cascade control (Voltage - outer, Current -inner). And also which safety protection must be carried out for testing in test bench?
Hi
I want to reduce insertion loss of cascade 1:2 Wilkinson divider for 110GHz.
How can I design arc with given width at CST?
Can someone post video file of an example?
Heparin does affect INR when larger bolus doses are given due to INR thromboplastin reagent inhibition, but is has minimal effect when smaller doses are used. Whatever the dose, is seems that INR should be affected since it inhibits the final common pathway.
I am looking into cross talk between 2 GPCRs and I wanted to understand how does GPCR dimerization occurs in order to activate downstream cascade?
can i help me, EES code for cascade Refrigeration system
For example
I have a cascade model of three enzymes and my reaction is as follows:
(please see the attached file)
In the reaction, I added three enzymes, the first substrate (glucose acetate) and the last substrate OPD and measured the last product (DAP). I ran the reaction in two different conditions:
1) I used various amount of 6-o-Acetyl glucose and kept OPD concentration fixed.
2) ) I kept 6-o-Acetyl glucose concentration fixed but varied OPD concentration.
In both cases I measured 3rd enzyme activity (by measuring the DAP production).
Now how can I calculate km for the last enzyme?
Thanks in advanced
Sharifun
I am planning to work on the effect of operating temperatures on the secondary flows in low pressure turbines, specifically the T106 cascade. I am unable to find any temperature range.
Hi! I'm little new on this signaling pathway, but I'd like to test if certain compounds can activate Notch signaling on HUVECs. As a positive control I'm thinking on using Jagged1. Which downstream genes could be indicative of Notch activation on this cells? Any protein on the signaling cascade that could be measured too? Many thanks in advance!
I realized a system connected to an electricity grid and I would like to know what level of voltage should I produce to inject renewable energy into the grid? would it be an cascaded H-bridge inverter 5-levels, 7-levels, 9-levels or even 15 or 21-levels? On what criteria will my choice be based?
Enstrophy is the integral of vorticity square over the flow domain/surface of interest. The unit dimensions of enstrophy is m^2/s^2. The enstrophy flux has been used in several studies to investigate the characteristics of turbulence cascade. However, there is no consensus on the basic physical mean of enstrophy in time/frequency/wavenumber domains. I would like your opinion on this.
It would really help to find candidate genes in an easy to handle internet platform which are transcribed by specific transcription factors (e.g. NFAT) to dissect signal transduction cascades from the plasma membrane to the nucleus and to cell function.
I'm reading a paper about CRISPR and they say: "To investigate whether the CasE subunit is sufficient for pre-crRNA cleavage activity, it was overproduced as a fusion with the E. coli maltose binding protein (MalE). Like the complete Cascade, the CasE fusion protein cleaved only the K12-type precrRNA (Fig. 2D), showing that CasE is an unusual endoribonuclease that does not require the other Cascade subunits."
I don't understand why they fuse the CasE to the maltose binding protein of E. coli (MalE). Is it because this MalE is naturally over produced?
Thanks
I just read your article about Trihydroxy-10E-octadecanoate generation as a fungizide on GIT-Labor.de from 2016 (https://www.git-labor.de/forschung/lebensmittel/trihydroxyfettsaeure)
Are there any recent publications focusing on the (chemo-)enzymatic reaction cascade for the production of those TriOHs?
I would like to present this topic to my students in a lecture about industrial biocatalysis.
Viruses such as Epstein Barr, cause stress to the CNS, which then activates mMC that begin an unending inflammatory cascade resulting in activation of Th-17 pathogenic lymphocytes, oxidative stress, oligodendrocyte cessation, and recruitment of B-cell plasma.
I am going to design a multilevel inverter, for this how i set the values of L and C
Hi
I have a two-loop control system (cascade control system). The outer loop aims at generating the inner loop reference input so that the global system output tracks its reference input. Each loop has a controller which needs to be designed. First, I used two PID controllers and I got a good response for ramp and sine for both loops, but when applied a step as the desired trajectory, the inner loop did not result in a good response.
What to do in designing controllers for two loop controllers?
The phenomenon of infection, infectious processes and infectious diseases is very complicated and interesting. Scientific research of the infection cannot be reduced to the creation of vaccines for humans and domestic animals. In the manifestation of infection and the periodic spread of infection (epidemics and epizootics), many connections are manifested. They are often not registered. Climate change carries new infectious threats. This is a very typical manifestation of how changes in the environment may lead to a cascade of consequences. Including infectious nature. In the discussion, it is necessary to focus on theoretical and methodological issues. They are key. Important interpretation of various cases of manifestations of infectious diseases among humans and animals. The purpose of discussion is to develop effective scientific positions on the study of the natural phenomenon of infection. Infectious ecology allows to go beyond the very limited approach of modern epidemiology and veterinary medicine. We are trying to reach a new level of understanding of relationships in nature.
I need PATC code in any language preferably matlab.
Hi everyone,
I currently make nanostructures on single crystal gallium oxide with Ne+ bombardment. I am interested to know how the surface and bulk compositions are being affected during the process. At the lab I have access to EDX, Raman and XPS but I have no experience with any of them.
Usually my structures consist of having a narrow pillar (radius 100nm or less) surrounded by a trench (width 400nm or more). Although the beam does not go on the pillar, there might also be a change in its composition due to cascade effects. Therefore ideally I would like to measure the surface/bulk compositions of (1) the pillar; (2) the surface where atoms were sputtered; (3) somewhere else on the sample where no radiation occurred as a reference. I'm expecting a higher concentration of Ga at the surface than originally, but that might not be the case.
How would you recommend to proceed? I understand that the size of the structures might be a limitation, so I thought that I could obtain a qualitative measurement of the pillar using EDX, while I could do bigger trenches for Raman and XPS regarding the sputtered surface. I read that XPS has a lateral resolution of 60µm, which is way bigger than my structures! Is that so? I could do bigger structures, but not that big (10µm at most I suppose).
Thank you very much in advance for your suggestions.
Julien.
This connected potentials can accurately describe the displacement cascades in graphite. I would like any suggestions about how to connect AIREBO and ZBL potentials using a Fermi function or spline function. Thanks.
Could anyone possibly tell me about similarity parameters in experimental set up in the annular cascade test rigs? I would be grateful if you could tell me what kind of non-dimensional parameters needs for aerodynamic similarity between experiments and real operations conditions in annular cascade tests for axial compressors? "Corrected mass flow", "pressure ratio", "Reynolds", "Mach number", which parameter (or parameters) is necessary? I want to use surface oil flow visitation on last stators in incompressible flow in annular cascade test rig.
Dear all,
With access to high-speed time-synchronized data provided by phasor measurement units (PMUs), real-time state estimation becomes possible for power system monitoring, protection
and control. While most of PMU-based research work focuses on real-time state estimation or filtering including static and dynamic states in power systems, my questions are:
1. How can these processed PMU data be used for detection and identification of abnormal system state?
2. How can this knowledge (real-time state, detection and identification of abnormal system state) be used to improve resilience of power systems? (such as loading shedding, isolation schemes and generation tripping under cascading failures)
Thanks very much and appreciate your reply.
Regards,
Hehong
I am working on the geochemistry of a pluton in the Cascades. It ranges in chemistry from diorite to granite, and whole rock major element harker diagrams indicate they share a common parent source. However, the behavior of Th is confusing me. I've never seen an inverse relationship between Zr/Th vs Th. Any comments would be much appreciated!


usage of goals cascade properly according to stakeholder needs is the most important issue in effective COBIT-5 application. usage and application of procesess should be primarily laid on needs of stakeholders. therefore requirements analysis is the core. your project can help ISACA in issuing another version of COBIT X.
There are hormonal replacement options but why not drugs to bypass the coagulation cascade altogether?
fine and ultrafine aerosol sampling
DVT is mostly observed in patients of mitral stenosis....I have read that when blood passes through stenotic valve it activates clotting cascade leading to hypercoagulable state that is responsible for DVT..Please explain is it true? Is there any reference
So I need to model a single phase inverter, through function blocks and mathematical equation. I have a real time simulator D-space, through which I can add on the close loop functions and complete my system. Can anyone has some references for this kind of system..?
/Anup
PS is phospholipid cell membrane and in contact with TF Tissue factor involved in the initiation of coagulation (enhances the effect of the cofactor). Does PS - do the same factors can bind and activate a cascade of plasma clotting?
If there are two resonant circuit inductively or capacitively coupled, then how to design the small signal model of one-only (i.e, for only the transmitter side LC series resonant circuit), while considering the effect of another(transmitter)?
Iam using a basic cascade voltage multiplier to boost and rectify the 0.3v ac signal. The circuit rectifies but the boost is very less. So I thought of using LTC3105 after this stage to get a regulated dc output voltage. Problem in simulation is it is taking really long time to simulate moreover LTC3105 is not boosting up below 0.5 v but according to datasheet LTC3105 starts up at 0.25 v. Can you please help me out with this?
Just wanting to know since I know only about tank cascades in India.
I am trying to find THD of 2 H-Bridge cascade Multilevel inverter. THD calculated using THD Formula and the THD in FFT analysis are different for a particular case, in all other cases it matches exactly. so which one is accurate THD in MATLAB or THD by formula?
Please find the THD formula which have used attached
The exsting system has a cascaded control with volume flow rate as quantity of major interest, being controlled in primary loop and controller in secondary loop controlls the valve position. Both are PI controllers. I want to design optimal controller for this system, so can I just replace outer(primary) PI controller with optimal controller with inner PI controller still controlling valve position or I should redesign whole as one optimal controller?
Is there any publication on vane cascades with heterogeneous outlet angle. This is, the outlet angle varying from vane to vane?
I need to reproduce the bifurcation diagram of the Rossler attractor while varying the parameter C (period-doubling cascade) using MatCont.
I have been reading tutorials and trying on my own with no succes.
Could anyone give me some help on this topic? I would really appreciate it.
Thanks in advance.
Bruno Rango.
I'm running ANSYS FLUENT simulation on a compressor cascade, and I wonder if the growth of the separated flow regions could affect the number of iterations required to reach convergence, and why is this the case? Thanks in advance Ahmed.
I am designing shunt Active power filter with cascaded h-bridge 5 level MLI.how to derive capacitance, should i take capacitance value for each bridge and should i require seperate reference voltage for each phase,PI controllers?
I need how to set the timing in one complete full cycle of sine wave output will get using H-bridge configuration(i.e., 16 IGBT switch) (or) I need control circuit diagram...
I need to know how the timing in one complete full cycle of sine wave output will get to use the 4 H-bridge configuration (i.e., 16 IGBT switches) (or) I need the model control circuit diagram.
Wnt, Hh, Bmp's etc. Gene-expression/ protein changes marking stages in normal colon development
I am working on Space Vector Pulse Width Modulation Technique. I wanted to determine the switching sequence of switches of Cascaded Multilevel Inverter.
I am designing a control technique for three Phase rectifier in MATLAB.
Using two PI controller block, outer for voltage control and inner for current control connected in cascade. I tried to tune the model using trial and error method and got output assigning DC voltage reference. Output voltage is following the reference voltage but when I change the voltage reference value the resultant voltage is not changing according to reference value. e.g. If I set reference value as 400 and use trial and error method, output will follow the reference value and settled to 400 but when ref value is changed, say it is now 200 then output voltage is pulsating from 0 to 400 instead of following 200 reference value. Can anyone please suggest a solution?
I am doing my thesis on compressible turbulence. In case of incompressible 2D turbulence, in the usual study materials, the energy is shown to be an eulerian invariant and the enstrophy as a lagrangian invariant. The existence of an inverse cascade of energy cascade is then argued to exist thanks to these two conservations. In fact for incompressible turbulence the lagrangian and eulerian invariance in this case are equivalent. But for compressible turbulence we have the square of vorticity/density which is a lagrangian invariant but not an eulerian one. On the other hand total energy is an eulerian invariant. Can these two conservations make some possibilities of an inverse cascade too?