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Cardiovascular Surgery - Science topic

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This article is available to be requested from the author in Research Gate. Have you tried asking for it?
There are a few articles which are available on the internet for download. Hope these help you find what you are looking for.
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We prefer Bivalirudin. Please send me your experiences and dosage regimes.
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I think Bivalurudine is a safe alternative to Argatroban in HIT patients. It has a shorter half life of about 30 minutes. Heparin is still the preferred anticoagulant on CPB. 
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I am a cardiovascular surgery resident, i am looking for a topic to investigate and it will be my research thesis. Any suggestions?
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Ecocardiography follow-up aortic valve replacement versus tavi
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There is no powerful evidence to support any specific threshold. The study reported by the Yale group reported an increase in complications at sizes of 70mm (Davies 2002), but most consensus guidelines suggested repairing them at 55mm. Given the lack of natural history data, what are the arguments for and against this aggressive threshold?
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in young patients 5 cm size
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Most consensus lines suggest you to repair them at 55mm. What are the arguments for and against this aggressive threshold and which percentage of patients don't need surgery since during the follow up the aneurysm diameter doesn't increase significantly?
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Thank you again Olena, very interesting links and considerations. Think it would be useful more studies on it...becouse the bifurcation point you rightly mentioned is the key point where speed of growth is supposed to change
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Hi,
I need to open aorta en face for O red oil staining purpose. Does anyone know any tips on how to do this. My problem is more to technical part which I really don't know how to get a nice longitudinal incision / enface opening of aorta. I have tried multiple times but the aorta tear throughout its length. Should I open the aorta enface while it still attached to vertebrae? And should I open aorta en face first, pin it to dish / wax, then only after that do ORO staining.? Is there any video guide about how to open this aorta. 
thank you very much.
Help is much appreciated.
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Hello,
You can thread a flexible tube or catheter(OD of tube<ID of aorta) through aorta before detaching it from the body. after you make sure you are all the way through, pin the two ends of the tube and start working on your aorta. That helps.
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Would it be bispectral index or exhausted anaesthetic gas from CPB circuit (analogue to end tidal anaesthetic gas)?
Many thanks for your time and atttention,
Ka
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Dear Ka,
Attached please find the requested pdf file.
Regarding the End-tidal approach, please see the following text: 
End-tidal Control is intended for use during inhalational anaesthesia and needs a controlled patient airway to be in place, for example an endotracheal tube or laryngeal mask airway.
End-tidal Control cannot be used with a face-mask airway, or with halothane as the anaesthetic agent, or while the module is in non‑circle circuit, cardiac bypass, alternate oxygen, and air‑only modes. It is recommended that End‑tidal Control is not used during surgical procedures that cause disturbance to the lungs, such as chest surgery. The system may deliver 100% oxygen in End-tidal Control mode, therefore End-tidal Control mode should not be used when delivery of 100% oxygen may injure the patient (for example, in premature neonates in whom excessive inspired oxygen concentrations can cause retinopathy, or in patients with some forms of congenital heart disease). End-tidal Control mode stops if the anaesthetic is changed while the module is active. The manufacturer recommends exiting End-tidal Control mode before changing the anaesthetic. However, it is not routine practice to change anaesthetic agent between the anaesthetic room and the operating theatre.
The manufacturer does not specify a lower age limit for End-tidal Control, however specified respiratory rates (35 breaths per minute or less) must be met, and the system must be registering a minute volume.
The following link contains a publication on this approach.
Hoping this will be helpful,
Rafik
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Some changes following administration of Histidine-Tryptophan-Ketoglutarate (HTK) Custodiol including Anemia and hyponatremia are not uncommon in our cardiac patients. However we have noticed degrees of hematuria in our patients who have received Custodiol Bretschneider solution). Although wasting of the cardioplegic solution was effective in some patients, my last patient had hematuria on the contrary to the wasting of the solution. I didn't find any report in the literature. Please share your ideas about the reason and possible solutions.
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We have used Custodiol in 5-10 cases/year for several years and we have never had cases of hematuria.
Best regards
Kari Kuttila
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cardiovascular surgery
cardiology
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With most things being said already, let me just add some minor remarks.Effective venting of the left ventricle  is even more important in cases with transfemoral canulation compared to central canulation, as the retrograde flow  leads even earlier to a closure of the aortic valve and may thus cause a distension of the left ventricle. We do recently use a small 2.5 Impella(R) pump for an active venting of the LV at a rate of <2 l/min and also use this device for a stepwise weaning. So we reduce the ECMO flow and remove this system with the heart still under low support by the Impella(R) pump, which can then be turned down the day after.
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Actually, I am concerned with the association between the use of contrast agents and rupture of thoracic aortic dissection (Stanford A type).
Here is the case I experienced recently. A 57-year-old male with a history of hypertension and atrial fibrillation visited our department with a complaint of chest pain. His consciousness was clear and his systolic blood pressure was 100 mmHg. TTE revealed dilated ascending aorta along with moderate aortic regurgitation. Immediately, contrast-CT was performed. Contrast enhanced CT revealed Stanford A type aortic dissection. There was no retention of pericardial effusion. Within a few minutes after that, he fell into CPA. TEE revealed massive retention of pericardial effusion. PCPS was introduced. However, PCPS did not work efficiently probably because of collapse in the right heart. Immediately, pericardial drainage was performed; drainage was not effective because of coagulated blood.
In this case,
Should we have performed pericardiotomy to save this patient?
May contrast agents trigger the rupture of thoracic aortic dissection (Stanford A type)? Actually, I know several cases that thoracic aortic dissection ruptured immediately after contrast CT. I want a paper discussing this point.  
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1- I doubt it's the contrast media (it can be catheter)   2- In my >50 yrs experience, I know of several cases of rupture of aneurysms in X-ray.   In fact, we long noted that with acute traumatic rupture of the aortic isthmus, the Radiology Department (& transportation) is very dangerous! 3- Acute intrapericardial rupture of a dissection is VERY unlikely to benefit from  pericardiotomy outside the OR. 
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Does anybody know how to implant stent model into virtual vessel vessel model for CFD studies ? Maybe someone know special software or method how to deform a straight pipe model of a stent to fit a vessel geometry. I need to deform it something like the image in attachements
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Hi Herman,
Tthank you very much for reply. Unfortunately I'm interesting in a developing a technique for stent modeling using CAD software. The problem is that I can not find any guide of how to deform a stent to fit a vessel. In all publication they present only a final stent geometry but there is now description of how to do it on practise.
With best regards,
Sergey
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We operated a case of a women with a debut of giant cell arteritis with an acute ascending aorta dissection and I don't find many series with this kind of presentation of aortitis.
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as far as i know not
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revascularisation options in egg shell aorta
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Depending on the general condition of the patient, if the patient is very fit I would add ascending aortic replacement to the  revascularization surgery. Again, if the patient is very fit LIMA-radial artery Y graft for the revascularization of LAD and OM; and RIMA for the revascularization of RCA can be done, off pump without replacement of the ascending aorta. Otherwise in an average patient, I would not push too hard for LIMA + RIMA. Off-pump complete revascularization can be performed  (Y graft with LIMA and radial artery: LIMA-LAD, radial artery to OM and PDA). Hybrid is a good choice if you do not have difficulties of revascularization of OM during off-pump CABG; hence, you can do Y graft with LIMA and radial artery; it is: LIMA-LAD, radial artery to RCA bypass.
I do not like saphenous vein graft on arterial conduits and I rather prefer arterial conduits on arterial conduits. 
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Viability scan, assessment of angina and dyspnea and fractional flow reserve are some of the tools. A very important paper by John Elefteriades (Circulation 1999) says that revascularizing even scarred myocardium benefits the patients in terms of symptomatic and survival improvement.
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For indication it's clear that myocardial viability and suitable coronary arteries are needful prerequisites,  along with risks factors just mentioned
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On pump versus off pump CABG what are your reasons?
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During last 15 years I am doing all coronary cases on beating heart. My ezperience is
a little bit less than 2000 operations. I am absolutely convienced in priority of OPCAB surgery as many of  my colleagues .
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What is an acceptable ACT for you (PERFUSIONIST) to start the pump (cardiopulmonary bypass)?
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480 seconds
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Patient is currently under antibiotic therapy for prosthetic (bovine) valve endocarditis, CRP is almost negative, there are no vegetations and no insufficiency of the valve. Therapy will last for two more weeks. Knee replacement surgery is scheduled in four weeks. Should we wait longer? How Long?
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In any case - the prognosis of "prosthetic" endocarditis of the bioprosthetic heart valve  is  poor  and any surgical procedure may provoke him.
However, let me know what was the basis for the diagnosis of "prosthetic" endocarditis?
Did You based on any "large" criteria (obviously, one of the "big" criteria absent - no vegetations on the valve), or on a set of "small" criteria? What exactly?
Have there been attempts to detect other foci of infection, in addition to the valve implant?
Has a procalcitonin test?
If we are talking about an infectious lesion of the bioprosthesis and successful antibiotic treatment, I would advise you to delay implantation of the knee up to 6 months.
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Dobutamine is considered as the first line inotrope for perioperative hemodynamic support in cardiac surgery by some of the classic references. What is your inotrope of choice? Have you stopped dobutamine due to adverse effects?
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Well well well -
the point is what do I need the drug for......
1. if i have anesthetic side effects - low BP due to Propofol etc - and the rest of the heart is fine - NA is the drug of choice.
2. if I have low CO and adequate BP - the point is to increase CO with inotropic support and afterload reduction - dobutamine, milrinone, enoximoen etc are fine - and studies exist
3. if there is severe impaired CO - the use of adrenaline together with afterload reduction (i.e. milrinone, phenoxybenzamine, phentolamine, etc.) is the combination of choice - may be as an add-on to the things mentioned above
4. if there is low BP - needed for organ perfusion - some NA may be helpful if dobutamine lowers the BP too much
5. dopamine - especially low dose - is useless and only increases afterload and shows a good BP, only increases the rate of sepsis, impairs endocrine function, has no effect on kidney function, etc, etc,
here you are - open for discussion
Nik
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Could you recommend the best device for A-fib surgery?
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The epicor System may be a good tool for Afib ablation during cardiac surgery. The system uses high intensity focused ultrasound (HIFU) energy.