Cardiology - Science topic

Some diseases require high doses of medicine due to the depth of the disease or its intractability. Meanwhile, the use of high doses of medicine causes unpredictable side effects, Also, one of the desired factors for the effectiveness of drugs is their release at the desired place and time to increase the efficiency of these drugs. One of the facto...

Objective: to analyze the emotional response of critically-ill conscious patients during daily hygiene procedures in a Cardiology Intensive Care Unit and to compare it based on the existence of previous experiences or not. Method: a prospective and descriptive study. A 30-item ad hoc survey based on the first-day hygiene procedures was applied to 1...

Background: For patients having aortic valve replacement (AVR), the St. Jude and TTK Chitra mechanical heart valves are both often utilised in daily practise. The effectiveness of these valves is still up for discussion, though. Therefore, the purpose of this study was to investigate the outcomes of patients who underwent AVR with a St. Jude mechan...

Introduction. Point-of-care ultrasound (POCUS) use is now universal among nonexperts. Artificial intelligence (AI) is currently employed by nonexperts in various imaging modalities to assist in diagnosis and decision making. Aim. To evaluate the diagnostic accuracy of POCUS, operated by medical students with the assistance of an AI-based tool for a...

Patients with chronic myeloid leukemia (CML) treated with nilotinib or ponatinib may experience arterial occlusive events (AOEs). It is currently recommended to thoroughly assess cardiovascular risk factors before treating CML. We identified 455 consecutive CML adult patients, 335 treated with nilotinib and 120 with ponatinib; 380 patients without...

Myocardial infarction (MI), commonly known as a heart attack, is a critical medical condition resulting from the blockage of one or more coronary arteries. MI has been classified differently over time, with the most recent classification proposed by the European Society of Cardiology and the American College of Cardiology. This new classification c...

Aims We aim to investigate the association between kidney dysfunction and left ventricular diastolic dysfunction parameters and heart failure with preserved ejection fraction (HFpEF) and whether this is sex‐specific. Methods and results We included participants from the HELPFul observational study. Outpatient clinical care data, including echocard...

Aims The multi‐systemic effects of heart failure (HF) resemble the spread observed during cancer. We propose a new score, named HLM, analogous to the TNM classification used in oncology, to assess the prognosis of HF. HLM refers to H: heart damage, L: lung involvement, and M: systemic multiorgan involvement. The aim was to compare the HLM score to...

Since 2020, we have developed a 5-pillar rehabilitation program at MediClin and examined the course of symptoms (13 scaled items on admission and discharge). Inpatients were recruited at 6 clinics with the departments of psychosomatics, neurology, pulmonology, internal medicine/cardiology or oncology. Accompanied by an expert board of all specialti...

Background Reflexology is a popular non-invasive complementary medicine technique to enhance anxiety, pain, and fatigue among patients undergoing coronary angiography. Objective This study aimed to investigate the effect of hand reflexology in ameliorating anxiety, pain, and fatigue among patients undergoing coronary angiography. Methods A quasi-...

Aim. To evaluate the antihypertensive therapy and adherence to treatment in patients with uncontrolled arterial hypertension. Materials and М ethods. The study included 297 patients hospitalized at the E.I. Chazov National Medical Research Center of Cardiology over the period from September 2019 to March 2022. Patients were spread into two groups d...

Preventive nutrition in cardiology has a bright future ahead of it, as there is abundant data to justify its importance in secondary prevention. Practitioners must appropriate these simple data to meet patients' expectations. Our work consisted in showing the interest of nutrition and moderate physical activity in the secondary prevention of risk f...

Systemic hypertension is a global public health problem. It affects all parts of the population. In Algeria, according to the TAHINA 1 study, high blood pressure is the most common chronic pathology (24.8%). Despite numerous recommendations from learned societies 2.3.4.5 and the existence of effective therapies, a high percentage of patients remain...

Dual practice within public hospitals, characterised by the concurrent provision of public and private healthcare services within public hospitals, has become a widespread phenomenon. With the participation of selected public hospitals, dual practice within public hospitals, also known as Full Paying Patient services, was an initiative the Ministry...

Purpose Prompt endovascular treatment of patients with stroke due to intracranial Large Vessel Occlusion (LVO) is a major challenge in rural areas because neurointerventionalists are usually not available. As a result, treatment is delayed, and clinical outcomes are worse compared with patients primarily treated in comprehensive stroke centers (CSC...

The 2018 American Heart Association (AHA)/American College of Cardiology (ACC)/Multisociety blood cholesterol guidelines recommend clinicians consider adding non-statin therapy for patients with very high-risk (VHR) atherosclerotic cardiovascular disease (ASCVD) and low-density lipoprotein cholesterol (LDL-C) ≥ 70 mg/dl while receiving maximally to...

Long-term outcomes of iatrogenic coronary dissection and perforation in patients undergoing percutaneous coronary intervention (PCI) remains under-investigated. We analyzed 8,721 consecutive patients discharged after PCI between 2008 and 2019 from Keio Cardiovascular (KiCS) PCI multicenter prospective registry in the Tokyo metropolitan area. Signif...

Background The advancements in wearable technology have made the detection of arrhythmias more accessible. While smartwatches are commonly used to detect patients with atrial fibrillation, their effectiveness in the differential diagnosis of supraventricular tachycardias (SVT) lacks consensus. Methods A study was conducted on 47 patients with docu...

Heart failure (HF) is a multiple hormonal deficiency syndrome which includes alterations in the serum concentration of thyroid hormones (TH). This cross-sectional study enrolled 215 male patients hospitalised for acute HF. Data on cardiovascular risk factors, chronic medications, cardiac function assessed by echocardiography, and clinical parameter...

Objectives We aimed to prospectively describe incident cardiovascular events among people living with HIV (PLWH) in northern Tanzania. Secondary aims of this study were to understand non-communicable disease care-seeking behaviour and patient preferences for cardiovascular care and education. Design A prospective observational study. Setting This...

Objective This study aimed to assess the prognostic significance of residual (discharge) dyspnoea in acute heart failure (AHF) patients. Design Single-centre, prospective observational study. Setting Patients hospitalised for decompensated AHF in a single cardiology centre, in Poland. Participants All patients (n=202) who survived the hospitalis...

Background Early treatment of acute myocardial infarction is crucial to reduce mortality in these patients. However, not all patients arrive early enough to receive optimal therapy, especially in developing countries. Many factors can lead to increased pre-hospital delay. This study aimed to detect the frequency of delayed patients out of the total...

Background This study was undertaken to explore the predictive value of the advanced lung cancer inflammation index (ALI) combined with the geriatric nutritional risk index (GNRI) for all-cause mortality in patients with heart failure (HF). Methods and results We enrolled 1123 patients with HF admitted to our cardiology department from January 201...

Introduction Cardiac Dyssynchrony is prevalent among patients with heart failure with high cost of care and potentially poor outcomes. Nevertheless, little is known about cardiac dyssynchrony among heart failure patients, especially in developing countries. This study aims at assessing the predictors and outcomes of cardiac dyssynchrony among heart...

We aimed to evaluate sex differences in the effects of moderate-intensity statin with ezetimibe combination therapy (rosuvastatin 10 mg plus ezetimibe) versus high-intensity statin (rosuvastatin 20 mg) monotherapy in patients with atherosclerotic cardiovascular disease (ASCVD). This was a sex-specific subgroup analysis of the RACING trial that eval...

Purpose of Review To summarize selected late-breaking science on cardiovascular (CV) disease prevention presented at the 2023 European Society of Cardiology (ESC) congress. Recent Findings The NATURE-PARADOX was a naturally randomized trial that used genetic data from the UK Biobank registry to create “cumulative exposure to low-density lipoprotei...

Eye tracking technology has emerged as a valuable tool in the field of medicine, offering a wide range of applications across various disciplines. This perspective article aims to provide a comprehensive overview of the diverse applications of eye tracking technology in medical practice. By summarizing the latest research findings, this article exp...

Emerging research indicates that high HDL-C levels might not be cardioprotective, potentially worsening cardiovascular disease (CVD) outcomes. Yet, there is no data on HDL-C's association with other CVD risk factors like myocardial fibrosis, a key aspect of cardiac remodeling predicting negative outcomes. We therefore aimed to study the association...

Introdução: a fragilidade é uma síndrome multifatorial de condições biológicas, psicológicas e sociais que predispõe a pessoa idosa a declínio da funcionalidade e maior suscetibilidade à vulnerabilidade. Tal condição pode ser agravada naquelas que apresentam comorbidades, destacando-se as cardiopatias. Objetivo: conhecer a prevalência de fatores re...

Objectives: To find simple clinical signs for diagnosing pulmonary embolism on bedside. Methodology: This was a hospital based cross sectional observational study conducted in cardiology department Saidu teaching hospital from July 2019 to December 2020. 89 patients of either sex and all age groups with suspected pulmonary embolism (PE) were includ...

The early career professionals in the field of Cardiovascular Magnetic Resonance (CMR) face unique challenges and hurdles while establishing their careers in the field. The Society for Cardiovascular Magnetic Resonance (SCMR) has expanded the role of the early career section within the society to foster the careers of future CMR leaders. This paper...

Objectives: The objective of current study was to assess the correlation between serum uric acid level and severity the severity coronary artery disease (CAD). Methodology: This descriptive study was carried at department of Cardiology, Lady Reading Hospital, Peshawar during the period 5th January 2023 till 10th August 2023.Patients with coronary d...

Objectives: This study is aimed to determine the factors that influence the selection of sub-specialty training among adult cardiology FITs and whether this differs by gender. Methodology: A multiple-choice online survey was conducted on 198 cardiology Fellows-in-training (FITs) in Pakistan from January-May 2023 to assess the determinants of their...

Coronary microvascular dysfunction (CMD) is a common complication of ST-segment elevation myocardial infarction (STEMI) and can lead to adverse cardiovascular events. This is a non-randomized, observational, prospective study of STEMI patients with multivessel disease who underwent primary PCI, grouped based on whether they underwent balloon pre-di...

This study aimed to determine the in-hospital mortality rate associated with No Reflow During Primary Percutaneous Coronary Intervention. The study was conducted at the Peshawar Institute of Cardiology Hayatabad, Peshawar, between January 2023 and June 2023. A total of 90 patients who underwent primary percutaneous coronary intervention (PCI) for a...

The exponential growth of the elderly population poses considerable obstacles to healthcare systems on a global scale, hence requiring the implementation of inventive strategies to identify and mitigate age-related illnesses at an early stage. The primary objective of this study is to explore the use of big data analytics to improve healthcare prac...

A paracoccidioidomicose é uma doença fúngica sistêmica causada pelo fungo Paracoccidioides brasiliensis. Essa infecção fúngica é mais comum na América Latina, especialmente no Brasil, e pode afetar pessoas de todas as idades, incluindo crianças e adolescentes. O objetivo do estudo foi descrever um caso de paracoccidioidomicose juvenil na forma agud...

Quality improvement knowledge is a requirement of fellowship training. Our goal was to evaluate the efficacy of a 3-year quality improvement and patient safety (QI/PS) curriculum that gives fellows both didactic knowledge and first-hand experience with improvement science, and meets Clinical Learning Environment Review (CLER) requirements. Knowledg...

Prescribing appropriate exercise is an important means to improve the safety and efficacy of cardiac rehabilitation. Improper exercise may induce an increased cardiovascular risk in older persons with coronary heart disease. Cardiopulmonary exercise testing (CPET)-guided cardiac rehabilitation could be helpful for providing clinical evidence for ca...

In just over a decade, there have been paradigm shifts globally in the catheter-based therapies available for the management of patients with severe aortic stenosis. The use of transcatheter aortic valve replacement (TAVR) has been a crucial turning point in the field of cardiology as it granted an option for a minimally invasive method to replace...

Introduction Several key symptoms must be present for the accurate diagnosis of patients with postoperative cardiac delirium. Some patients present with symptoms of delirium but do not meet the diagnostic criteria for delirium; such individuals are considered to have having subsyndromal delirium (SSD). SSD is associated with misdiagnosis and poor o...

Background: Data published by task groups of the Ministry of Health of the Russian Federation, the European Society of Cardiology, and other medical associations and institutions show that chemotherapy-induced cardiomyopathy is still a challenging issue that requires further research. Objective: To compare the cardioprotective potential of trimetaz...

Treatment adherence is one of the milestones in the care of hypertensive patients, with new information and communication technologies as potential educational tools. This study aimed to evaluate the add-on effect of a digital cartoon educative video on the therapeutic observance of patients followed up in the General Hospital Yaoundé compared to s...

A prospective examination of laboratory errors was performed during three months from July to September 2019 at the Rawalpindi Institute of Cardiology (RIC), a 272-bed tertiary care hospital serving the Punjab region and parts of Azad Jammu and Kashmir (AJK) and Khyber Pakhtunkhwa (KPK). The study aimed to thoroughly evaluate error incidence rates...

Objectives: Employees of uniformed services (EoUS) were screened for cardiovascular risk factors. Material and methods: A total of 1138 EoUS (age M±SD 49.9±6.0 years) and 263 controls (age M±SD 54.4±9.7 years) under the care of the cardiology clinic in Gdańsk, Poland, were included in the study. Medical history and blood samples were collected,...

Objective: This investigation aims to assess the predictive value of the glycemic dispersion index (GDI), calculated by incorporating glycated hemoglobin, fasting plasma glucose, and 2-hour postprandial plasma glucose, in predicting major adverse cardiovascular events (MACE) within a 12-month timeframe for diabetic patients with concomitant acute c...

Menopausal symptoms can disrupt the life course of women at the peak of their career and family life. Currently, the most effective treatment for these manifestations is menopausal hormone therapy (MHT). The presence of cardiovascular and metabolic diseases in itself does not exclude the possibility of prescribing MHT to relieve menopausal symptoms...

Introdução: a DRC é uma patologia que impacta fortemente a vida dos seus portadores. É extremamente importante considerar seu diagnóstico precoce e intensificar a vigilância entre os portadores de hipertensão arterial sistêmica e diabetes mellitus, correlacionando com marcadores precoces de lesão renal. Objetivos: avaliar a presença de albuminúria...

Background: Radiofrequency catheter ablation is an emerging curative modality of treatment for paroxysmal supraventricular tachycardia. The aim of our study was to evaluate our experience of electrophysiology procedures and radiofrequency ablation over a 2-year-period. Methods and result: All patients undergoing cardiac electrophysiology and radiof...

Fundamento: As mulheres estão em minoria nas pesquisas científicas na cardiologia, e em se tratando de Infarto Agudo do Miocárdio Com Supradesnível de ST (IAMCSST), os estudos mostram que elas apresentam piores desfechos clínicos quando comparadas aos homens. Por isso, é necessário pesquisar sobre a razão pela qual há uma diferença entre os sexos p...

A Hipertensão Arterial Sistêmica (HAS) é definida como uma doença crônica não transmissível, caracterizada por níveis elevados de pressão arterial, que afeta mais de 1,2 bilhões de pessoas no mundo inteiro. Trata-se de uma doença extremamente custosa para os sistemas de saúde, pois envolve custos diretos e indiretos. Considerando este contexto, é v...

Anxiety or depression after percutaneous coronary intervention (PCI) is one of the key clinical problems in cardiology that need to be solved urgently. Brain-derived neurotrophic factor (BDNF) may be a potential biomarker for the pathogenesis and treatment of anxiety or depression after PCI. This article reviews the correlation between BDNF and car...

Smartphone-based technology for ECG recording has recently spread as a complementary tool for electrocardiographic screening and monitoring in adult horses and in other animal species. The present study aimed to assess the feasibility and accuracy of a smartphone-based ECG in healthy foals. This was a prospective observational study (authorization...

Introduction Heart failure (HF) is a global health issue affecting millions of people worldwide. Cognitive frailty, a syndrome characterised by physical frailty and cognitive impairment without dementia, is increasingly recognised in this population. Cognitive frailty is associated with worse outcomes, including increased hospitalisation, disabilit...

Purpose of review This review aims to update healthcare providers on contemporary diagnostic and treatment information pertaining to aortic stenosis. Recent findings The prevalence of aortic stenosis continues to increase, and so does the burden of treatable disease. This has important implications for healthcare systems and the economy. Accurate...

Background Genomics-based clinical diagnosis has emerged as a novel medical approach to improve diagnosis and treatment. However, advances in sequencing techniques have increased the generation of genomics data dramatically. This has led to several data management problems, one of which is data dispersion (i.e., genomics data is scattered across hu...

Background There are no robust data addressing the United States (US) experience with the 0/2 hours (h) European Society of Cardiology (ESC) algorithm using high-sensitivity cardiac troponin T (hs-cTnT). Purpose To evaluate the diagnostic performance of the 0/2h ESC-recommended absolute deltas in a US population. Methods Observational US cohort s...

Purpose of Review Patient decision aids (PDAs) are tools that help guide treatment decisions and support shared decision-making when there is equipoise between treatment options. This review focuses on decision aids that are available to support cardiac treatment options for underrepresented groups. Recent Findings PDAs have been developed to supp...

Background Elevated level of lipoprotein (a) [Lp(a)] is an independent risk factor for atherosclerotic cardiovascular disease. However, the association of Lp(a) with acute coronary syndromes (ACS) has not been sufficiently studied. Purpose To evaluate the relationship between high serum levels of Lp(a) and (i) factors that play a role in the long-...

Introduction Mitral regurgitation (MR) is the most prevalent valve disease in Europe, mostly degenerative. In Brazil, on the other hand, there are few recent epidemiological data and previous studies show a higher prevalence of rheumatic disease. However, a change in the epidemiological profile of valve disease has recently been observed, largely d...

The largest challenge in modern cardiology is certainly sudden death (SD). Sudden death is described as an unanticipated, nontraumatic death that occurs within an hour of the development of new or worsening symptoms, within 24 hours of the last time the person was seen alive. Genetic, environmental, or acquired factors may all play a role in SD. In...

Background Due to the growing number of complex (multimorbid) patients, integrating and coordinating care across medical specialties around patient needs is an urgent theme in current health care. Clinical leadership plays an important role in stimulating coordination both within and between specialty groups, which results in better outcomes in ter...

As people live longer, the number of individuals aged 75 and above is increasing. This makes it crucial to provide careful medical care for elderly cardiac patients. Our study was conducted at the Punjab Institute of Cardiology and involved 300 patients divided into three age groups: those under 60, those between 60-75, and those over 75. Participa...

Background ChatGPT, the trending novel artificial intelligence has triggered ongoing debate regarding its capabilities.Recently, preliminary reports showed that answered correctly in the majority of questions of the United States Medical License Examinations (USMLE). However, its ability to succeed a more precise, challenging and high-stakes post-g...

Background Guideline-directed medical therapy (GDMT) is the cornerstone in the treatment of patients with heart failure and reduced ejection fraction (HFrEF) and novel substances such as sacubitril/valsartan (S/V) and sodium-glucose co-transporter-2 inhibitors (SGLT2i) have demonstrated marked clinical benefits. We investigated their implementation...