Cardiology - Science topic

I am a senior medical student in Zagazig University faculty of medicine (Egypt) with a strong interest in neurology, cardiology, and hematology/oncology, and I am eager to expand my research experience in these fields. I have foundational knowledge in medical research methods such as SRMA and have participated in clinical and laboratory-based projects during my studies.

I would like to inquire if there are any ongoing research projects or collaborations within these specialties where I could contribute, either through data analysis, literature reviews, or hands-on assistance in clinical studies. I am also open to participating in interdisciplinary projects related to general medicine.

Any advice or suggestions for getting involved in current research initiatives or learning opportunities in these areas would be greatly appreciated.

Thank you!

Hello, I’m a second-year medical student eager to develop my research skills, particularly in cardiology and the surgical field. I’m looking for guidance on how to start exploring research opportunities in these areas. Does anyone have any idea where to get started?

How can people effectively integrate data from genomics, metabolomics and microbiomics in individualized treatment of cardiovascular disease to achieve more accurate disease prediction and treatment plans ？

In the identified case of familial desminopathy (T341P DES mutation in heterozygous state), the son has bradycardia, but the father did not have bradycardia. How can this fact be explained?

Hello everyone,

I am a new PhD student starting a project on microRNAs (miRNAs) in myocardial infarction (MI) patients. I would greatly appreciate any guidance on the following points to ensure proper sample collection, storage, and analysis:

Your guidance will be instrumental in helping me get started on my PhD project.

I can not find this journal in the SCOPUS list from february 2023. Thank you for your help.

looking for researchers that are willing to work on discussion part and risk of bias of a systematic review, for more details pls leave a message

Thanks!

I red a paper on an important journal of cardiology. In this work they found that 8 miRNAs were dysregulated in plasma samples of a study cohor of 1710 participants (Controls + patientes affected by Heart failure). I evaluated these 8 miRNAs in plasma samples in a study-cohort of 129 subjects (Controls + Heart failure patients) and I found that only 2 miRNAs were dysregulated according to the work I red. Because I have to explain thi data in "Discussion" I don't know how to explain this difference. Why could be the main reason of these different results? Maybe the size samples or other? Thank you

Please visit:

Heart Attack Deaths Drop Over Past Two Decades - American College of Cardiology (acc.org). It says "Researchers found the overall rate of death from heart attack, adjusted for age, fell from about 87 deaths per 100,000 people in 1999 to about 38 deaths per 100,000 people in 2020".

The reduction may be the result of awareness, better preventive care, obesity reduction, etc.

My question is about a simple step in health care. Has any research been done about the value of a six-monthly blood pressure check and related consultation in reducing heart attacks? A related question is a similar reduction in strokes.

Obviously, this healthcare is not available to the average resident of most developing countries.

Should it not be?

Srinivasan Ramani

Have you ever wished that there was a platform that could help students and researchers learn and grow? A place where you could find mentors, educational resources, and opportunities to publish in international journals?

Well, that's exactly what we wanted to create. But to make this dream a reality, we need funding. We are looking forward to spreading the word far and wide about their mission to empower the next generation of researchers.

The platform we are launching will be a game-changer in the world of academia. We are already working on this platform now. The content is really interactive, unique and really valuable. The community and environment will be very competitive. Researchers and students will be able to find the opportunities to enroll in with supervision and review.

And so, thanks to the dedication and hard work of a few passionate individuals, the world will become a better place, one researcher at a time. If you're looking to make a difference in the world of academia, I highly recommend donating in this amazing platform.

I want to do a good and worthy research in field of cardiology (DM Cardiology), suggestions for a topic , ideas are most welcome. Thanks in advance.

ECGs from patients with normal sinus rhythm, sinus arrhythmia and paced beats in the time domain might look very similar for a person without any cardiological skills. However, when looking at the same ECGs in the frequency domain I think most people see that paced beats look really different. The paced beats have a perfect U-shaped pattern, while the sinus and sinus arrhythmia rhythms are characterized by a more noisy pattern. I feel pretty sure that the perfect U-shaped pattern is caused by the regularity of the paced beats, but I don't have a scientific explanation of why this happens.

Searching for a formula to convert into excel for my student's research. Found:

Risk_Factors = (ln(Age) * 3.06117) + (ln(Total_cholesterol) * 1.12370) - (ln(HDL_cholesterol) * 0.93263) + (ln(Systolic_blood_pressure) * On_blood_pressure_medication) + Cigarette_smoker + Diabetes_present - 23.9802Risk = 100 * (1 - 0.88936e(Risk_Factors))

Not sure how to convert it for one and it doesn't make provisions for BMI! Can probably figure out how to do the conversion for the original with time, but then I am still missing the ingredient for the special sauce of this research! Why not just ask my international peers for help? Pretty please.

I want journals related to metabolism cardiology this for experimental studies on animals

Given the multiple cardiology meetings that we have now, I would like to know which of the meetings you are attending have the mist impact on you education and practice?

To save life in desminopathy, can the body purposefully reduce muscle mass, for example, due to decreased heart function or for another reason?

It is known that when hypothermia, the body sacrifices limbs for survival. Is it possible with desminopathy a similar phenomenon?

We're conducting a research design as follow:

My question is as follow:

Nuclear medicine physicians and cardiologist have disagreement in time of application of cardiac SPECT and coronarography in cases suspected for coronary disease.

Nuclear physicians consider that cardiac SPECT is one non invasive method with very high efficiency for detection of coronary disease.

Cardiologists consider that cardiac SPECT is not sufficient for detection of coronary disease and prefer coronarography as first diagnostic method   

At what AAA size would you consider Cardiac Nuclear PET/SPECT with Lexiscan over Dobutamine Stress Echo? (outpatient setting)

How important is the potential for a hypertensive blood pressure response with use of Dobutamine?

How important is the presence or absence of a previously placed graft?

What are other clinical factors on which you would base your decision?

-comments greatly appreciated!

Deborah Williams, NP 

Plaques form due to a self-healing mechanism of blood vessels and will increase over time. When entering blood vessels, they block blood flow, lead to hypertension and decrease blood flow to organs such as the heart. To get rid of these plaques, we need to boost the good cholesterol such as HDL or improve health of liver to produce enzymes that move these plaques. So, what other ways to get rid of these plaques without using invasive methods?

Thanks and best regards.

Sometimes when I am thinking about visual system, my memory also "connected" to my friend who is cardiologist.

we know that at visual cortex there are area V1 V2 and so on.

In cardiology we also know Lead V1 V2 and so on. Are there any relationship between the visual pathway and the cardiology pathway ? If there are none, how to delete one of them from our memory ?

Planning to write on Covid-19 associated myocarditis. I am a junior doctor without subspecialty qualification in Cardiology, with a special interest in Cardiology.

Any suggestion on non-predatory journals with a good acceptance rate even for non-specialists? Skipping Cureus for now.

There seems to be a lot of controversy about the validity of HRV as a measure of vagal tone. Specifically, Marmerstein, McCallum, & Durand (2021) published a paper suggesting the lack of correlation between HRV and vagal tone. Are there better, non-invasive ways to clearly and accurately measure vagal tone? So much of the literature over the past few decades focuses entirely on HRV in some way or another. Is this still an accurate way to measure vagal tone?

As Feigenbaum said, it takes only five minutes to perform a 2D longitudinal strain evaluation in patients who underwent cardiotoxic chemotherapy. Is it part of your routine cardiac ultrasound examination?

How can a patient safely taper off bisoprolol 2.5 mg who used it once daily? What schedule can he follow to taper off gradually? Any reference/paper/textbook for doing this?

I'm looking for an excel sheet to calculate the STS Score. From the website http://riskcalc.sts.org/stswebriskcalc/calculate. Does anyone have a worksheet to calculate the STS Score?

Need to change Hossam Kandil

picture and affiliation

Hossam Kandil

Professor of Oral maxillofacial radiology, Cairo University

Not Cardiology

This is wrong

Kindly help me correct the error.

Thank you

Shereen Shokry

Main Author

I've been grappling with this question for a very long time. There must be a logical reason to explain why almost all humans have one bicuspid mitral valve and 3 tricuspid valves in their hearts.

In the same vein of thought,

I found some ECG along with PCG from Physionet 2016 challenge dataset with name "a". But, description of ECG is unknown hence i am unable to apply particular algorithm to detect important features. If there are any dataset of ECG along with PCG it will be of great help to my research. Thanks

I need its pathophysiology.

Where are the best places/institutes that I may find a PhD program for cardiology?

Which job positions are available for graduates of cardiology PhDs?

What requirements are needed for applying for a PhD program in cardiology?

Any other experiences if you have completed or are taking this PhD program...

I'm referring to the overlapping sigmoidal curves that are used to describe the gain-of-function mechanisms. I understand the activation curve, but I can't seem to get my head around the inactivation curve. Any help at all would be very much appreciated, whether that is an explanation or pointing to one in the literature. It would also be helpful if you could explain the holding potential, depolarising voltage steps, and pre-pulse vs test pulse. Thank you in advance!

My name is Mustafa and I'm currently in my 3rd year of my Biomedical Science major. I decided not to take any courses this spring and summer because I want to invest my time in studying the MCATs and also to help with research. Are there any scientist that want any help with research related to Cardiology or such related topics. I have an extreme interest and background information in Cardiac Pathophysiology and Cardiac rehabilitation and I'm also very good with excel. If you need any volunteer I am here for you. Thank you for taking the time to read this.

I have recently got my Bachelor's degree in medicine and surgery and I have finished step 1 USMLE recently. I am looking for a research opportunity in cardiology or cardiology-related basic science. I have good research experience. I can help in databases searching, statistic work or manuscript writing.

We are in the middle of a crisis, in the quarantines. Irresponsible behavior has brought us to our current state. We did not learn any lessons learned from viruses that preceded and resembled the COVID-19 virus. Today's topic is not the reason that led us to this situation but commenting on the measures we have taken. The study of (Bishwajit et al., 2017) examined the effects of physical activity on depression. Their study had a representative number of middle- and older-aged subjects (7204). They concluded that a lower frequency of vigorous physical activity was significantly associated with higher rates of depression diagnosed. Depression symptoms and physical inactivity are factors that are closely correlated with obesity (Garimella et al., 2016). The elderly population has a prevalence of anxiety and depression around 10 and 12 %, these findings are caused as a consequence of different factors. Health-related quality of life and physical function play an important role in depression and anxiety (Sousa et al., 2017). The logical conclusion is that physical activity can reduce the levels of depression. Many studies have addressed this topic. Throughout history, our race has evolved. From the beginning of the cognitive, through the agricultural and industrial revolution to the present, we can observe a trend of decline in physical activity. This trend was accompanied by the appearance of metabolic and chronic diseases. Chronic diseases are major killers in the modern era. Physical inactivity is the primary cause of most chronic diseases. (Booth et al., 2011). Physical activity primarily prevents, or delays, chronic diseases, implying that chronic disease need not be an inevitable outcome during life.

This brief introduction is just a small overview of the literature that has examined the topics of physical inactivity, depression, and chronic illnesses.

Because we are in quarantine, and our movement is restricted and in some environments disabled we face many difficulties. Speaking personally and listening to people from my surroundings, from a psychological point of view, quarantine has a rather negative impact on people. With this, the media and the internet, which is full of misinformation, make people panic.

Reference:

Bishwajit, G., O’Leary, D. P., Ghosh, S., Yaya, S., Shangfeng, T., & Feng, Z. (2017). Physical inactivity and self-reported depression among middle-and older-aged population in South Asia: World health survey. BMC geriatrics, 17(1), 100.

Booth, Frank W., Christian K. Roberts, and Matthew J. Laye. "Lack of exercise is a major cause of chronic diseases." Comprehensive Physiology 2, no. 2 (2011): 1143-1211.

Garimella, R. S., Sears, S. F., & Gehi, A. K. (2016). Depression and physical inactivity as confounding the effect of obesity on atrial fibrillation. The American journal of cardiology, 117(11), 1760-1764.

Sousa, R. D. D., Rodrigues, A. M., Gregório, M. J., Branco, J. D. C., Gouveia, M. J., Canhão, H., & Dias, S. S. (2017). Anxiety and depression in the Portuguese older adults: prevalence and associated factors. Frontiers in medicine, 4, 196.

Topics:

1) Coronary Physiology Assessment for the Diagnosis and Treatment of Coronary Artery Disease

2) Non-coding RNAs in coronary artery disease: new and potential therapeutic targets

3) Refractory angina pectoris: an unsolved problem?

These articles will be part of a Special issue on "Coronary artery disease" that will be published in Cardiology Clinics Journal (IF 2.01).

No Publication Charges

Mandatory Deadline May 1st

Please contact me privately if interested

Sincerely,

Alberto Polimeni

---

March 14th , all papers were already assigned. Thank you for your help and contribution

I'm looking to get a better sense of whether gait speed is mostly used as a research tool, or if people are using it in medical practice, based on real experiences. My initial research seems to indicate that it's indeed a research tool, but it seems it is also used in cardiology/thoracic surgery to assess post-operative risk.

What have been your experiences with gait speed? How are you currently measuring it? (Any relevant references or links are also greatly appreciated!)

Hi, I could not find any reliable articles about the patients with intracranial traumatic contusion bleeding, with traumatic SAH or subdural hematoma. Cardiologists are pretty strict about giving ASS, Clopidogrel and Heparin despitr the bleeding in the head. Do you guys have some ideas how to achieve a maximal compromise on both sides (neurosurgery and cardiology?

Their is need to understand the safety and efficacy of exercise therapy on cancer treatment–induced cardiovascular toxicity and tumor progression and metastasis in oncology practice, this can be achieved by having a fundamental knowledge of exercise prescription, dosing and personalization with regards to cancer treatment and according to global best practices.

Is iron ingestion from cooking pots still a problem?

Anyone see Haemosiderosis cases?

And how do they differ from Haemochromatosis?

The patient should consult which specialty if he wants to know, will he stop aspirin prior to the operation or not? Will he consult the Cardiologist, the surgeon or the anesthesiologist?

The European Society of Cardiology guidelines and strategies such as TRAPID AMI aim to stratify patients into low ("rule-out"), intermediate & high risk ("rule-in")  for AMI/ACS based on serial troponins, ECG, risk factors etc.  For obvious reasons a >99% sensitivity is the defacto standard for rule-out.  What then should be the specificity or ppv be? While ppv will vary according to prevalence, it matters to the cardiologists what proportion of patients they are told high risk actually have the disease.  I'd like input, especially from cardiologists, on what they think is an acceptable ppv rate and why?  Thanks.

statin use,low risk cardiovascular patient,mortality benifit,

Is there any epidemiological data/ prevalence of left atrial remodelling (assessed mainly by left atrial volume) in patients with HFrEF AND AF

I have recently repeatedly observed pulmonary haemorrhage in association to an appropriate use of the LUCAS device by different team for OHCA CPR. This was very different from haemorrhagic secretions, that can somtimes occur during prolonged CPR.

Any thoughts or experience?

Thanks

Tobias

Dear Colleague,

Sri Lankan Journal of Cardiology- January 2019                                 (Official Publication of Sri Lanka Heart Association) We are pleased to inform you that the above mentioned issue of SLJC has been published. The next issue has to be published in time for the Annual Academic sessions of the Sri Lanka Heart Association, in June 2019. Hence, we earnestly solicit a  contribution from you .It would be greatly Appreciated and extremely valuable. We welcome, Reviews, Therapeutic Reviews, Research, Audits,Critiques of Guidelines, Analysis of important Trials, Milestones in achievements, Tutorials, Case Reports and Updates etc ,as contributions for the next issue of the SLJC.Could you please prepare your manuscripts and submit the same by end of April so that the editorial work could be completed in time (ruvan_nishali.ekanayaka@yahoo.com). The PDF version of this issue is attached herewith.  Thanking you in advance for your kind cooperation. Yours Sincerely, With Best regards,RuvanDr Ruvan EkanayakaMBBS,MD,MRCP(UK),FRCP(Lond),FRCP(Edin),FRCP(Glsg),FCCP, FACC,FESCConsultant Cardiologist / Editor in Chief SLJC

Clopidogrel is often used to keep coronary stents patent

Clopidogrel resistance can be up to 30% of African/Asian populations

Should we be doing more routine testing for the marker of resistance- CYP 19 in these populations? Otherwise we may be giving placebo to our stent patients...

It seems these particular database is not freely available in a simple Google search. Any help is highly appreciated.

Hi. Do we need to ask permission from the related publishers if we want to use tables and figures from journal article or a citation is enough ?

As we know, there is five phase of Korotkoff sound that could be heard during blood pressure measurement at patient's upper arm using non-electronic sphygmomanometer and stethoscope. Each phase of Korotkoff sound has a unique characteristics that could be distinghuished based on its acoustic parameters. From these parameters, in some research, we are able to know some physical condition of the vessel (like stiffness, age, etc.). But, could the features of each Korotkoff phases be intepreted directly as a sign of certain cardiovascular disease?

Is there any research on if/how a slightly dilatated thoracic aorta root dilatation (caused by high blood pressure and not Marfan) can be successful reversed? If not, what is the physiological reason that a dilatated aortic root (4cm) (caused specifically by high blood) pressure cannot return back to normal size after aggressive blood pressure control?

A 40 days premature neonate reffered other center due to large ra thrombosis.

.he hasn't positive history of cvp catheter .

in examination ,stable hymodynamic , normal saturation , gread 2/6 systolic murmur ,no sign of respiratory distress.

in echo: a large echogenic ,pedinculated ,moveable thrombus protruding to tv ,area about 1.1 cm2 ,mild tr with p.pg= 27 mmhg ,otherwise is normal .

what is your opinion about managment of this neonate?

best regards 

I want to isolate Monocytes from Thrombus, I don't know if it's possible, or if it's suitable to disintegrate the thrombus by aspirating up/down with a pipette then to isolate by Ficoll just like the classical protocol.

Any suggestion is needed :)

Thank you!

The Integrative Medicine is gaining popularity and acceptance as it consists of many healing therapies to treat many diseases. In mini form it is existing in India as Ayurved doctors always prescribes medicine, diet, yoga, meditation, mantra etc. but the present emerging IM is covering many existing therapies so domain is wider. There is need of a post-graduate course of general integrative medicine open for all medical graduates. As it advances the specialty integrative post graduate course may be introduced like integrative cardiology etc.

Vasodilators (e.g. ACE-I, BB, nitrates) are generally considered to improve blood flow.

There is some evidence indicating that vasodilators reduce delta P (arterial-venous pressure difference) which would seem logical as arteries can dilate more.

Blood perfusion is expressed as perfusion= deltaP/viscosity*resistance

If we decrease deltaP it would indicate lower organ perfusion?

In other words it seems that if you reduce the vascular resistance the blood will tend to circulate better but would also have a lower chance to leave the capillaries and reach the tissues.

For how long? Just 2-4 weeks? And is topical steroid necessary? Or it the patient can be on other medications without fearing complication? I.E does topical steroid prevent any serious complications? Or just treat the symptoms like Erythema?

The most commonly affected valve in rheumatic heart disease is the mitral valve. But why? is there any specific pathomechanism. I haven't found the evidence based answers yet.

I am going to induce acute myocardial infarction in rats by LAD ligation. As you know, the mortality rate in this model is usually high. What should I do to reduce the casualties?

I would be very grateful if you could give me some advice.

Hi,

I'm working on organ motion modeling specifically for radiation therapy. We do 4D MR acquisition to extract the characteristics of a subject respiratory motion, which is essential for planning of the therapy.

I'm wondering if the intra-subject variability of the respiratory or cardiac motion is also important for some sort of diagnosis. To the best of my knowledge, current dynamic CT or dynamic MR based methods only reconstruct single average motion cycles.

As I'm not a clinician this question might sound quite naive. However, I'm happy for any hints and answers.

Best

Christoph

58 year man with Achalasia cardia who underwent Trans thoracic Heller"s cardio myotomy in 1962, started c/o of regurgitation of liquids from nose and mouth mostly at night for over one year.Details of the procedure are not available.Requested to have Upper GI scopy,Manometry and 24hr PH.Not a diabetic or Hypertensive.No respiratory symptoms.

I see some Healthcare Professionals recommend Coenzyme Q10 supplementation because Beta Blockers deplete it. I tried to find evidence for this, and I didn't find except this paper.

So my Q, as a Pharmacist, do I have to supplement someone who is taking Bisoprolol or not? Because I didn't find also Bisoprolol mentioned in this paper.

I'm a cardiologist

what is the highest troponin achieved post myocardian ischaemia?

Is it after reaching the steady state concentration (3-5days) or it may take more days to reach the maximum effect for atrial fibrillation control?

how can a patient be managed having Atrial Fibrillation with rapid ventricular response ?

A - Tricuspid Regurtitation

B - Mitral Regurgitation

C- Aortic Regurgitation

what will be the maximum time when we can do PCI ?

I am going to treat the myocardial infarction rats with spironolactone for 8 weeks/56 days. As you know, there are several ways to administer this drug, such as oral (gavage and mixed in rat chow), intraperitoneal and subcutaneous injection. We currently cannot mix it with rat chow.

How to make the solution of it? Can we make the solution with physiological serum?

Your advice and suggestions will be much appreciated and welcomed.

The biomedical industry provide support for medical diagnostics & monitoring, cardiology, audiology, neurology, plus..

As we know,the pulse propagates in wave form and the velocity of wave propagation depends on the propagation medium features. So,Is it possible to use the measurment of velocity of pulse propagation in the body to diagnose cardiovascular problems such as hypertension and hypotension?

What is the mechanism that reverses this condition ?

Is Hypertension only risk factor for Abdominal Aortic aneurysm or it can be a risk factor for Thoracic aneurysm as well ?

Do we have any best test to run in diagnosing cardiac tamponade , or clinical signs are considered reliable here ?

Isolated Systolic Hypertension in elders is most likely due to rigidity in arterial walls . What is the reason that rigidity doesn't affect Diastolic Hypertension ?

I would be grateful if you could give me anything about this topic.

The fibrotic response after a myocardial infarction (MI) can be classified into two types of fibrosis:

1-Replacement or reparative fibrosis at the infarcted area (scar formation)

2- Reactive fibrosis outside the infarcted area usually after the replacement fibrosis

I would be grateful if you could give me anything about this topic.

I am going to induce acute myocardial infarction in rats by LAD ligation. I want to know what protocol is most suitable for getting to the heart.

I would be very grateful if you could give me some advice.

The video of your surgeries will also be very helpful.

Premise 1: Neurogenic bradycardia and RSA are mediated by different branches of the vagus and need not respond in concert.

Premise 2: Neurogenic bradycardia associated with orienting is a phylogenetic vestigial relic of t