Cannabis - Science topic

Single cell protein (SCP) is emerging as a viable alternative to conventional protein sources thanks to their low environmental footprint and resource upcycling potential. This study investigated the production of SCP from hemp (Cannabis sativa L.) biomass residues (HBRs) and cheese whey (CW) in an innovative one-stage sequential anaerobic–aerobic...

The use of medicinal plants in managing toxicological and pathological conditions has garnered significant attention due to their bioactive components and therapeutic potential. Artemisia vulgaris L. (A. vulgaris) and Cannabis sativa L. (C. sativa) are notable for their diverse pharmacological properties, including antioxidant, anti-inflammatory, a...

Wound infections in cancer and diabetic patients are a significant public health concern due to their complex etiology, delayed healing, and association with multidrug-resistant pathogens. Cancer-related wounds often result from surgical procedures, radiation, or tumor growth, while diabetic wounds are linked to neuropathy and vascular complication...

Background: The advent of virtual reality in psychiatry presents a wealth of opportunities for a variety of psychopathologies. Avatar Interventions are dialogic and experiential treatments integrating personalized medicine with virtual reality (VR), which have shown promising results by enhancing the emotional regulation of their participants. Nota...

Recognizing climate change’s severity, reducing the construction industry’s greenhouse gas emissions is crucial in material science, architecture, civil engineering, and construction science. Novel bio-based materials like hempcrete are being developed to lessen the environmental impact of construction. Hempcrete, increasingly used in traditional a...

For patients hospitalized with COVID-19, delirium is a serious and under-recognized complication, and people experiencing homelessness (PEH) may be at greater risk. This retrospective cohort study compared delirium-associated risk factors and clinical outcomes between PEH and non-PEH. This study used patient records from 154 hospitals discharged fr...

The impact of climate change has prompted government authorities to implement regulations aimed at reducing energy consumption and CO 2 emissions. The construction industry holds a prominent position among the major greenhouse gas emitters, contributing a large amount of global energy consumption. A significant portion of these emissions is attribu...

OBJECTIVE To compare the pharmacokinetics of cannabidiol (CBD) and cannabidiolic acid (CBDA) in horses and to evaluate the safety of their chronic administration. METHODS CBD- and CBDA-rich oil (1 mg/kg) were administered orally twice daily to 7 adult horses over 6 weeks in a randomized, crossover design with a 2-week washout period. A 12-hour pha...

The aim of this study was to assess the effect of selected plant additives on changes in the content of fatty acids, lipid quality indicators and mineral composition of yogurts produced from cow’s milk. The analysis included natural yogurts and yogurts enriched with 10% of chia seeds, hulled hemp seeds, quinoa seeds and oat bran. The fatty acid com...

Background Cannabis use has increased substantially in recent years, for both recreational and medicinal purposes. While the deleterious effects of cannabis use during adolescence on brain health are well acknowledged, long‐term implications of cannabis use on brains of older adults remain unknown. We explored the associations between past and curr...

Background We present Phase 1 trial data using the Neuropsychiatric Inventory (“NPI”) domains, NPI‐delusions and NPI‐hallucinations as symptoms of psychosis in participants with Alzheimer’s (“AD”) receiving IGC‐AD1, a combination of low concentration delta 9‐tetrahydrocannabinol (“THC”) and melatonin. Cannabis use is considered an established risk...

Background Cannabis‐based therapies have gained interest in treating different ailments in the elderly population, including severe or chronic pain, sleep disturbances, and more recently Alzheimer’s Disease. This raises the importance of understanding the influence of age on the pharmacokinetics (“PK”) of delta‐9 tetrahydrocannabinol (“THC”). IGC‐A...

Mycelium-based composites (MBCs) are highly valued for their ability to transform low-value organic materials into sustainable building materials, offering significant potential for decarbonizing the construction sector. The properties of MBCs are influenced by factors such as the mycelium species, substrate materials, fabrication growth parameters...

Purpose Cancer survivors in a state with no legal access to cannabis may be hesitant to discuss their cannabis use with providers, particularly in light of legal consequences which disproportionately affect certain racial groups. This study examined potential racial disparities in the relationship of cannabis use status with patient-provider discus...

Industrial hemp (Cannabis sativa L.) is an ancient crop used throughout history for fiber, oilseed, and therapeutic compounds. Hemp varieties were cultivated across diverse environments in the United States, but knowledge of those agronomic practices along with genetic resources was lost during a period in which cultivation of cannabis was prohibit...

Global soil salinization has become an increasingly severe challenge for agricultural production, particularly affecting the cultivation of economic crops in marginal lands. Industrial hemp (Cannabis sativa L.), despite its economic potential, exhibits a notable sensitivity to salt-alkaline stress, limiting its expansion in saline-alkali regions. T...

BACKGROUND Substance use has increased over time across different population groups. Between 1990 and 2010 the global burden of disease from mental health and substance use disorders (SUDs) increased by 37.6%. Healthcare workers are predisposed to substance use disorders and experience abuse and misuse of substances just like the general population...

Introduction Cannabis use and misuse are surging among the Chinese community in East and Southeast Asia. A quick screening instrument that can effectively identify users with dependence for early intervention is in utmost need. This study examined the psychometric properties of the Chinese version of the Severity of Dependence Scale for cannabis (C...

The amount of saturated fat in cookies can be reduced by replacing margarine with oleogel, resulting in healthier products. In this study, the rheological and textural profile of cookies formulated with oleogel as the main margarine substitute was evaluated. Hemp seed vegetable oil was oleogelized with four types of waxes: beeswax (BW), carnauba wa...

Importance The association between maternal medications and the macronutrient composition of human milk has not been studied. Objective To compare macronutrient levels in milk samples from mothers treated with long-term medications with samples from untreated healthy and disease-matched control mothers (DMCs). Design, Setting, and Participants A...

In the current scenario, Cannabis sativa has been highlighted due to the increasing use of its components in the treatment of various pathologies, both in human and veterinary medicine. The present study aims to identify the ways in which Cannabis sativa is used in Veterinary Medical Clinics today. For this, a methodology used for a bibliographic r...

Synthetic cannabinoids (SC) imitate the effects of natural cannabis and pose a particular concern for adolescents and young adults due to their low cost, legal ambiguity, and undetectability in standard drug tests. Yet, very little research has examined associations between using SC and natural cannabis (NC) in cannabis use disorder (CUD). The pres...

Background It is known that illicit and prescribed drugs impact pupil size, eye movement and function. Still, comprehensive quantitative evaluations under known ambient light conditions are lacking, when smartphones are used for monitoring. Methods In this clinical study (NCT05731999), four medicinal products with addiction risks were administered...

Transhumant pastoralism, characterized by the seasonal movement of livestock, has been a traditional practice in various forms globally for millennia. The Scandinavian shieling system—specifically, the Kårebolssätern site—exemplifies this practice, where designated areas provide grazing and dairy processing facilities. However, many of these system...

Heat can leave the body and enter the environment in several ways, including radiation, evaporation, conduction, and convection. Heat transmission between the human body and its environment is known as thermal management, and its goal is to maintain a comfortable body temperature by generating or storing body heat. Clothing regulates body heat and...

La creciente demanda de productos que favorezcan el bienestar físico y mental ha impulsado el desarrollo de alimentos funcionales, como las gomitas enriquecidas con cannabidiol (CBD), un compuesto de la planta Cannabis sativa conocido por sus propiedades antioxidantes, antiinflamatorias y ansiolíticas. Este estudio se centró en la formulación de go...

Background This study investigates the role of functional constipation (FC) in predicting the long-term success of Gastric Per-oral Endoscopic Myotomy (G-POEM) for treating gastroparesis. Methods This was a retrospective observational study. Patients who underwent G-POEM between July 2015 and August 2022 with > 6-month follow-up were included. The...

We investigated people living with HIV (PLWH)’s exposure to COVID-19 pandemic stressors and their association with distress, psychological growth, and substance use. PLWH in the ANRS CO3 AQUIVIH-NA cohort’s QuAliV study (Nouvelle Aquitaine, France) completed an adapted CAIR Lab Pandemic Impact Questionnaire (C-PIQ) and reported substance use betwee...

Background and Aim: Marijuana poisoning in canines is still considered a taboo topic. Poisoning in pets is becoming increasingly common, in many cases resulting in severe clinical signs, such as ataxia, urinary incontinence, mydriasis, depression, and hyperesthesia. Colombia does not have any reliable test for the diagnosis of exposure to cannabis...

The abundance of information sources in our digital environment makes it difficult to study how such information shapes individuals' attitudes towards current policies. Our study investigates how self-directed online search in a naturalistic setting through three randomized controlled experiments with 791 German participants on three topical policy...

Inflammation is the critical component of neuropathic pain; therefore, this study aimed to assess the potential anti-inflammatory effects of Cannabis sativa L. extracts in a vincristine-induced model of neuropathic pain. The effects of different doses (5.0–40.0 mg/kg) of two Cannabis sativa L. extracts (B and D) on COX-1, COX-2, TNF-α, and NF-κB mR...

We investigated the amount and distribution of waste generated by commercial tobacco, electronic cigarette, and cannabis (TEC) use to inform policy options aimed at mitigating the environmental harm caused by these products. Using disproportionate stratified random sampling, we selected 60 census blocks from the eight largest cities in San Diego Co...

Background Mental health and substance use disorders typically onset during youth and commonly co-occur. Integrated treatment of two or more co-existing mental health and substance use disorders (i.e., concurrent disorders) is increasingly prevalent in real-world clinical settings. However, the depth of the evidence base on best practices remains u...

This study explored the longitudinal associations between multiple dimensions of school belonging during adolescence and substance use in young adulthood. Data were leveraged from the Australian Temperament Project, a comprehensive, multi-wave prospective cohort study. The current sample comprised 1565 participants (804 women). School belonging (1...

This article examines narratives of cannabis legalization in Nigeria. While most existing research on cannabis legalization has concentrated on the global North, we focus on one of Africa's largest cannabis markets, as well as the views of actors heavily criminalized and excluded from policy debates. Based on in-depth interviews and long-time engag...

Background Differences in cannabinoid metabolism and patient responses can arise even with equivalent doses and formulations. Genetic polymorphisms in genes responsible for cannabinoid metabolism and medications that alter CYP450 pathways responsible for metabolism of cannabinoids may account for some of this variability. Materials and methods A r...

Background: This study aimed to investigate mortality due to tobacco use, matter-use disease, and psychiatric health issues among Iranian adults aged 18 years and over. Methods: Information from the 1856 Iranian National Survey of Psychiatry Health and Well-being was evaluated. This survey was a streamlined, multi-event likelihood sample of 12,555...

Children are highly sensitive to toxins which can damage their organs and lead to death. Investigating the main causes of intoxication could reduce mortality and morbidity in children. In this cross-sectional study, the documents of all poisoned patients (214 cases) admitted to the emergency department of Taleghani children`s Hospital between April...

Introduction: Substance use among prison inmates is a challenge for many countries around the world and this problem has imposed great waste of human, financial capital which leads to several health costs and social harm to the general community. Objective of this study is to determine the pattern of substance use among prison inmates in Sri Lanka....

Purpose of Review Sleep impairment due to chronic pain is linked to functional impairment and often inadequately addressed with current treatments leading some to seek alternative therapies, including cannabis. The factors associated with chronic pain and sleep impairments are disproportionately experienced by individuals from racial/ethnic minorit...

Background Adolescents face numerous challenges that influence their sexual behaviors. Among these, bullying victimization is a critical yet understudied factor that may impact engagement in unprotected sex. This study investigated the correlates of condom use among school-going Thai adolescents, with a main focus on bullying victimization. Method...

Hemp fibers have mechanical characteristics similar to those of synthetic fibers, which makes them an attractive material for producing environmentally friendly composites. Hemp fibers have excellent mechanical properties and a unique hydrophilicity, requiring for extra attention in composite formulations. Hemp fibers are a very versatile vegetable...

Ecuador enfrenta una grave crisis de salud pública debido al elevado consumo de drogas, posicionándose como uno de los países con altos índices de ingesta de alcohol, tabaco y marihuana en América Latina. El objetivo de este estudio es comprender el desarrollo del proceso de normalización del consumo de sustancias psicoactivas desde la perspectiva...

Introduction: There is a need to assess the delivery of interventions to improve substance use disorder (SUD) treatment, as measured by the Healthcare Effectiveness Data and Information Set (HEDIS®) metrics. The goal was to characterize published articles reporting HEDIS® SUD measures and recommend future work on applying and investigating SUD HED...

Purpose College students are at higher risk for problematic substance use and disordered eating. Few studies have examined the comorbid risks associated with OCD despite the increased prevalence of OCD among young adults. This study examined substance use and disordered eating risk associated with OCD conditions among college students and how this...

Background While research has explored the connection between addiction and personality, no systematic study has examined how substance use disorders (SUD) and behavioral addictions specifically relate to the HEXACO model of personality. This systematic review and meta-analysis aim to fill this gap by investigating the association between HEXACO pe...

Adolescence is a phase characterized by reckless and risky behaviors, including the initiation and use of various illicit substances such as cannabis and alcohol. When ingested or administered, these substances affect mental processes by delivering pleasure, inner peace, and satisfaction. The aim of this study was to determine the prevalence and as...

Introduction: Autism Spectrum Disorder (ASD) is characterized by deficits in communication and social interaction. Despite lacking a definitive cure, multidisciplinary therapeutic and pharmacological approaches are employed to mitigate their symptoms. However, the potential side effects of conventional treatments drive the search for alternatives su...

In the present study, ethanolic extracts from the extract of unshelled seeds of Cannabis sativa L. were used to produce films in order not to generate additional waste, taking into view a circular economy. Combinations of apple pectin and citrus pectin in a ratio of 80:20 were used. Film samples containing 0.5, 1.0 and 2.5 [wt%] of the extract were...

Biodegradable biopolymers like polyhydroxybutyrate (PHB) hold promise for sustainable packaging, but their inherent degradability reduces material stability. Synthetic stabilizers, though effective, raise environmental and potential toxicity concerns. This study explores a multifunctional natural anti-aging agent: a hemp extract rich in cannabidiol...

In 2022, the state of Alagoas, located in the northeastern region of Brazil, published new legislation regarding the medicinal use of Cannabis, which includes provisions for medical prescription , support for scientific research, continued education for healthcare professionals, and public events on the topic. Therefore, this study aimed to conduct...

Introduction: Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by impaired communication, social interaction, and repetitive or stereotyped behaviors in those affected. It presents with a wide range of symptoms, which can vary from mild to severe.Method: a search was conducted in the PubMed, SciELO databases, and the bo...

La adolescencia es un estado del desarrollo ontogénico caracterizada por una transición fisiológica y conductual gradual, que va desde la niñez hasta la adultez, e incluye importantes cambios hormonales asociados al inicio de la pubertad. Durante este periodo, los adolescentes muestran una mayor sensibilidad a estímulos gratificantes y una predispo...

Corrosion is one of the biggest challenges in metal surfaces, especially when scratches and impacts damage the coating. Self-healing agents in the coating ensure long-term protection, effectively shielding the metal from corrosion. However, these materials are not environmentally friendly in general. To improve sustainability, we propose encapsulat...

The purpose of this study is to analyze the factors affecting the tendency of farmers to grow hemp in Rize province of Türkiye. The data was collected by face-to-face survey method from 90 farmers with proportional sampling. A five-point Likert scale was used to evaluate farmers' knowledge levels, opinions and attitudes regarding hemp growing, and...

Introduction Substance use is a growing public health concern in West Africa, contributing to significant morbidity, mortality, and socioeconomic challenges. Despite the increasing prevalence, comprehensive data on the patterns and factors influencing substance use in the region remain limited. This systematic review and meta-analysis aim to synthe...

Background: Problem substance use is a frequent reason for consultation. Whether isolated or co-morbid with another pathology, it remains important to manage within a dual framework. Objective: The objective of this work is to describe the sociodemographic and clinical characteristics and addictive behaviors of patients who were admitted to the psy...

This small review shows the potential applications of Cannabis and Ginger extracts as potential drugs for brain disease. We focus mainly on the treatment of Alzheimer's, Parkinson's, and epilepsy diseases. All studied extracts are inhibitors of acetylcholinesterase and pose as promisor candidates for treating these diseases.

The rising concerns over substance abuse particularly involving Indian hemp (marijuana) and alcohol among university students in Nigeria poses significant health and social concerns, and necessitate innovative solutions for detection, effective monitoring and intervention strategies. Substance abuse among university students has become a pressing i...

Background: Cannabis sativa (CS) has been traditionally used for its medicinal properties, including antioxidant, antibacterial, and neuroprotective effects. However, its potential anticataleptic activity remains unexplored. Aim: This study aimed to investigate the qualitative phytochemical analysis, antioxidant, antibacterial, and anticataleptic a...

Background A few studies have examined psychological resilience as a predictor of physiological responses to acute stress; however, no studies have directly examined psychological resilience as a moderator of subjective responses to acute stress. Methods Adults were recruited to participate in an acute stress response study that was conducted remo...

The slides show average sound absorption data for commercial and experimental porous materials from producers and the literature, classified into 30 categories. The largest class are fibrous based materials, wood-, cellulose-, hemp-, polyester-, sheep wool-, mineral wool-, glass wool, seagrass- and similar-, and wood wool cement- fibres. Of foams w...

Traumatic brain injury (TBI) is a global health issue that leads to long-term neurological deficits, including cognitive, motor, and mood disorders. Current TBI treatments primarily focus on symptom management, while neuroprotective therapies remain in the exploratory stage. One promising approach is the use of Cannabis sativa L., which contains ph...

Substance use poses a significant public health challenge worldwide, including in Finland. This study seeks to predict patterns of substance use, aiming to identify the driving factors behind these trends using artificial intelligence techniques. This research utilizes data from the 2022 Finnish National Drug Survey, comprising 3,857 participants,...

Distribution transformers may experience insulation breakdown or degradation when exposed to the influences of high‐altitude electromagnetic pulse (HEMP), thus posing significant threats and uncertainties to the safety and stable operations of power systems. Therefore, this study constructs a HEMP impact‐test platform for distribution transformers,...

Purpose: The aim of the study is to compare and determine addiction tendencies in voluntary and probation (DS) applications in Adana province located in the Mediterranean regionof Türkiye. Materials and Methods: The study was planned as prospective and cross-sectional. 1007 people who applied to the alcohol and substance treatment center within a 1...

Em 2014, a luta de famílias pela regulamentação no Brasil do canabidiol (CBD), um dos canabinoides da cannabis sativa, trouxe força ao debate público sobre o uso medicinal na planta. O CBD, assim, passou a ser legal no país. Com o uso de teorias e métodos associados ao mapeamento de controvérsias, esse trabalho tem dois objetivos principais: 1) mos...

Empirical data on the effect of plant density (PD) and length of the vegetative phase (DVP) on plant growth, yield, and cannabinoid concentration of medicinal cannabis (Cannabis sativa L.) are still scarce, leading to a lack of specific cultivation recommendations. We conducted two greenhouse experiments to investigate the effect of PD in the range...

In India, a wide range of medicinal plants are reported. Since ancient times, these medicinal plants have been used by people for the treatment of several diseases. Herbal medicines typically have fewer side effects compared to synthetic medicines, and they are also non-expensive. The aim of this study is to evaluate the antioxidant, in vitro anti-...

Currently, there is increased interest in growing hemp as well as in large-scale hemp products. The main research focuses on the use of seeds and fibres. At the same time, the remaining hurd is proposed to be used for mulching, making insulation and bedding for animals. Due to the cellulose’s high content in its composition with a relatively low co...