COVID-19 - Science topic
Coronavirus disease 2019 (COVID-19) is a respiratory illness that can spread from person to person. The virus that causes COVID-19 is a novel coronavirus that was first identified during an investigation into an outbreak in Wuhan, China.
Questions related to COVID-19
The choices usually in conflict are, should we fix the root cause of the problem or should we just manage the problem?
The case of the pandemic shows that there were those who opposed the solution of the problem with Covid 19 vaccines to attack the root cause (the virus) of the problem to minimize severity of infection or chances of hospitalization or changes of death; and those who just wanted the Covid 19 to be managed in such a way as to facilitate the reaching of natural immunity regardless of death levels or severity of consequences of just managing the Covid 19 problem.
In the case of the Covid 19 problem most countries if not all, chose to attack the root cause problem with the vaccine.
In the case of the environmental pollution problem, the international and local community is focused since 2012 on managing the pollution generation problem instead of fixing the root cause of the pollution generation problem(distorted market prices).
In the case of the pollution generation problem most countries if not all, chose to avoid fixing the root cause pollution generation problem with green markets in 2012 as the environmental cost internalization as vaccine, and went instead with the way of managing the pollution generation problem with environmental pollution management based markets.
And this raises the question, is the goal of dwarf green markets like climate change markets to reach a level of natural environmental immunity locally and globally through pollution management? While leaving the root cause of the pollution generation problem unfixed?
What do you think? Yes, then why? No, then why not?
How do you think COVID-19 countermeasures taken by states and governments comply with the human rights guarantees established by national Constatutions and the International Human Rights Treaties? Among those measures are :
-mandatory usage of masks
During trials of Covid-19 vaccines, there have been attempts to explain the observed high level of Serious Adverse Events in volunteers who received Placebo jabs.
Nocebo Effect describes a situation where a negative outcome occurs due to a Belief that the intervention will cause Harm. I regard that highly unlikely in people who rolled up their sleeves as volunteers. Are any readers aware of Mandatory jab trials where people were coerced into accepting one or more Placebo jabs?
I attach a SEM picture of syringe needle tip that can be expected to leave some stainless steel in your arm if some of the flakes formed during manufacture break off, presenting a Nickel Hazard.
Numerous researchers are ignorant of the fact that injection with Sucrose also cause allergic reaction in some people.
The decline in the number of Covid-19 cases in Indonesia continues to occur. Activities such as school, work, and travel seem to be returning to normal. Is this a sign of the end of Covid-19 in Indonesia?
Please kindly leave your opinion in this forum :)
I am a very curious person. During Covid-19 in 2020, I through coded data and taking only the last name, noticed in my country that people with certain surnames were more likely to die than others (and this pattern has remained unchanged over time). Through mathematical ratio and proportion, inconsistencies were found by performing a "conversion" so that all surnames had the same weighting. The rest, simple exercise of probability and statistics revealed this controversial fact.
Of course, what I did was a shallow study, just a data mining exercise, but it has been something that caught my attention, even more so when talking to an Indian researcher who found similar patterns within his country about another disease.
In the context of pandemics (for the end of these and others that may come)
I think it would be interesting to have a line of research involving different professionals such as data scientists; statisticians/mathematicians; sociology and demographics; human sciences; biological sciences to compose a more refined study on this premise.
Some questions still remain:
What if we could have such answers? How should Research Ethics be handled? Could we warn people about care? How would people with certain last names considered at risk react? And the other way around? From a sociological point of view, could such a recommendation divide society into "superior" or "inferior" genes?
What do you think about it?
Cancer incidence is increasing globally. It is widely believed that increased life span is the main reason cancer risk overall is rising. A paper published in the Lancet reports that delays in screening, diagnosis, and treatment due to the COVID-19 pandemic could lead to excess cancer deaths, and slow or even reverse the declining trend in mortality projected for some cancers. https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(22)00111-6/fulltext
Furthermore, the report by Harvard Medical School researchers at Dana-Farber Cancer Institute and colleagues from other institutions, suggests that COVID-19 has complicated the treatment for patients with cancer. "In patients with cancer, COVID-19 can be especially harsh. This is likely because many of these patients have a weakened immune system—either as a result of the cancer itself or the therapies used to treat it—and are therefore less able to fight off infection by the new coronavirus". https://hms.harvard.edu/news/covid-19/cancer-interplay#:~:text=In%20patients%20with%20cancer%2C%20COVID,infection%20by%20the%20new%20coronavirus
In 2021, a research team led by Zhou highlighted the clinical and molecular similarities between cancer and COVID-19 and summarized the four major signaling pathways at the intersection of COVID-19 and cancer, namely, cytokine, type I interferon (IFN-I), androgen receptor (AR), and immune checkpoint signaling. They also discussed the advantages and disadvantages of repurposing anticancer treatment for the treatment of COVID-19. https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/1408
Jafarzadeh et al. reported that the patients with some types of cancers may be more vulnerable to SARS-CoV-2 infection compared with the non-cancerous individuals, due to their immunocompromised state resulted from malignancy, chemotherapy, and other concomitant abnormalities as well as perhaps greater expression of angiotensin-converting enzyme 2. Moreover, they reported that clinically recovered COVID-19 individuals display immune abnormalities that persist several months after discharge.
The lymphopenia-related immunosuppression, functional exhaustion of cytotoxic lymphocytes (such as CD8+ cytotoxic T-cells and natural killer cells), hyperinflammatory responses, oxidative stress, downregulation of interferon response, development of the myeloid-derived suppressor cells, downregulation of tumor suppressor proteins and perhaps reactivation of the latent oncogenic viruses may directly and/or indirectly play a role in the cancer development and recurrence in severe COVID-19 patients. https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/1408
Has anybody done research on the comparison of in-class teaching vs online-teaching (during covid 19 pandemic):
e.g. effects on learning progress, student satisfaction, sucess in exams, ....
Thank you for any hints.
I've been interested in COVID stuff recently. Most of the current detection/diagnosis strategies need amplification. I can understand that RT-PCR can probably break the capsid because of the high-temperature processes. But how does that work for isothermal methods like RT-LAMP, since the temperature is not that high?
Also, if we want to directly detect or do something with the viral RNA, do we need to break the capsid and release the RNA? If yes, is there any established protocol? Many thanks!
Due to the energy crisis, the government's promotion of dirty combustion energy and the restriction of the development of emission-free green energy, will air quality in the heating season significantly decrease and the incidence of respiratory diseases and Covid-19 increase?
Various types of hard coal, lignite, pellets and firewood are allowed as fuel in Poland. However, even before the current energy crisis, in previous years it happened that some citizens threw various types of waste, including, for example, tyres, into the cookers heating their homes. As a result, air quality in Poland during the heating season (autumn and winter) was very poor in many cities and towns, failing to meet European Union standards. In many towns and cities there are no municipal guards or other services to control what is thrown into the heating cookers. However, there are already efficient systems in place in many countries to control what people heat their homes with. As part of the construction of such a control system, drones may be used, for example, which fly up to the chimney of a house and examine the composition of the fumes contained in the smoke coming out of the chimney. In Poland, only in a small number of cities, towns and villages are such modern methods used to control what citizens heat their homes with, i.e. what is thrown into the heating cookers. Because the current government, which has done almost nothing about this for the last seven years, so the state of the air in many cities is bad. This results in the deterioration of the health of citizens who inhale toxic substances contained in the fume-polluted air. Many citizens are dying prematurely due to respiratory diseases and other diseases resulting from inhaling carcinogenic toxins in the air. Due to the fact that the present government has impeded the development of renewable and emission-free sources of energy and financially supported the coal-based power industry, at present still 3/4 of the electricity and heat generated in Poland comes from dirty exhaust gas power. In order to make such statistics submitted to the EU authorities look a little better, the government-controlled Central Statistical Office has classified firewood as a renewable energy source. From an ecological, environmental and climate point of view, this is absurd and the government's treatment of citizens as mindless lemmings. The wood approved for firewood is untreated and unpainted wood. But even such wood burned in cookers releases harmful substances, including particulate matter PM2.5 etc. The absorption of these particulates reduces the body's resistance to allergens, to pathogenic viruses. The development of allergies and the incidence of respiratory diseases and Covid-19 increases significantly. Research shows a correlation between the level of PM2.5 etc. and a decrease in the human body's resistance to disease, a decrease in the efficiency of the immune system and the incidence of viral and other diseases. An election campaign is currently underway in Poland in connection with the parliamentary and local elections to be held in 2023. In connection with the election campaign, the main activists of the ruling PIS monoparty are carrying out pro-government propaganda at election rallies in various cities. Analogous pro-government propaganda is carried out in the government-controlled meanstream media. As part of this propaganda, the government is trying to shape the consciousness of citizens by suggesting that Poland is well prepared for an energy crisis, that the government is efficiently pursuing an anti-inflation policy and that the climate crisis is an environmentalist fantasy. Citizens who also listen to and read the existing independent media know that all that is reported in government propaganda is not factually correct. And besides, it happens that members of the government and/or the president of the currently ruling government monoparty PIS suggest to citizens the kinds of actions that are harmful to citizens. For example, at one of the press conferences, at one of the election rallies, the chairman of the currently reigning government monoparty PIS suggested to citizens that they can throw anything into their cookers except tyres, that they can heat their homes with anything except tyres. So that if someone runs out of coal, they can throw in, for example, plastic waste, the burning of which generates carcinogenic toxins. The current government has failed to ensure that there is no shortage of environmentally and air quality compliant fuel during the current energy crisis. The government has failed to implement a pro-environment and pro-climate transformation of the energy sector. The government has blocked the development of renewable and zero-carbon energy sources for 7 years by financially supporting the unprofitable, dirty coal power industry. Inflation is rising and, according to economists' forecasts, real core inflation in Poland will be the highest in Europe in 2023. And the government is introducing further subsidies and handouts for the purchase of fossil fuels, which are becoming additional pro-inflationary factors. Therefore, by the anti-environmental and anti-climate measures of energy policy in Poland, the currently developing energy crisis will be deeper, fossil fuel prices will be higher, air quality will be bad during the heating season. The scale of respiratory diseases and Covid-19 may increase significantly in the next heating season. Besides, the level of diversification of energy sources and the development of green, pro-environmental and pro-climate energy is low. Consequently, the level of energy security is also low. The question that arises is why a large proportion of citizens, estimated to be around a third of the population, still accept this kind of policy. This is how it looks in the country where I operate. And how do these issues look in your country?
In view of the above, I address the following research question to the esteemed community of researchers and scientists:
Due to the energy crisis, the government's support of dirty combustion energy and the restriction of the development of emission-free green energy, will the air quality during the heating season significantly decrease and the incidence of respiratory diseases and Covid-19 increase?
I invite you all to discuss,
Thank you very much,
Good afternoon: I'm preparing my first thesis about the level of readiness of nursing students to clinical practice during the covid-19 endemic period, is there a recommendation for a questionnaire or instrument that I can use? Thank you.
Some recent articles suggest that we need to rethink about JIT because COVID-19 has disrupted supply chains. In my opinion, ability of top management team may play a vital role in the management of JIT post COVID-19. What do you think? Hi! I am an early career researcher. In 2019, I graduated with a PhD in Accounting from Monash University (that too on my birthday!). In my PhD thesis, I argue that human capital (i.e., ability of the top management team) plays an important role in the efficient management of Just-In-Time Inventory. "Findings suggest that managerial ability contributes to efficiency in JIT inventory management with the extent of such efficiency being conditional on the level of discretion granted to managers and the effective monitoring of such discretion", (Ranjeeni, 2019). Please access the link below for more details: https://lnkd.in/gvZxfN3u My apologies for any errors or omissions as this is my first post aimed to generate a conversation on something that I did for my PhD and still think is applicable post COVID-19. Your kind comments, views and experiences will be helpful in contributing towards my learning and future research as an early career researcher. Thank you!!! 🙂🙂🙂 Reference: RANJEENI, KUMARI (2019): Do More Able Top Management Teams Unconditionally Lead to Better Internal Operations? A Case of ‘Just-in-Time’ Inventory Management. Monash University. Thesis. https://lnkd.in/gX-8D5vx #JIT #ManagerialAbility #PhDThesis
Various researchers have placed the Pfizer Comirnaty products under the microscope and report emergence over time of various bodies, proposed to be extended colloid strings.
In some cases, thin platelet crystals are observed, with some people proposing they could be Graphene Oxide, secretly added as an undisclosed ingredient.
The original formulation contains added Potassium Chloride, Potassium Dihydrogen Phosphate and Sodium Hydrogen Phosphate Dihydrate, so that I would expect to see Phosphate salts precipitate ahead of any other salts.
Has anyone isolated and reported the chemical composition of these crystals?
Who is willing to discuss this with me to help me find a better research gap in this research field? Thanks.
I am working on time series about COVID-19 Data interested in the subject
"Robust Forecasting with Exponential and Holt -Winter " and compute all my results in R packages, therefor I need help in:-
1- any new paper in this filed
2- Codes of Holt-winter smoothing in r
Thank you for any help
With Best Wishes
Pfizer reports that one of its chemicals used in formation of Liquid Nanoparticles used to gain cell entry for its genetically modified mRNA Covid-19 jabs, ALC-0315, is metabolized to 2-hexyldecanoic acid and an apparently previously unreported Hydroxybutyl, Bis-Hydroxyhexyl Amine, molecular weight of 289.454, that they observed via Mass Spectrometry in its protonated form and as its Glucuronide salt excreted in rat urine.
Pfizer reported terminal phase elimination half-lives (t½) were similar in plasma and liver, 6-8 days for ALC-0315.
There have been many thousands of reports of Anaphylaxis immediately after injection of the Pfizer product, and many reports of survivors suffering Biphasic Anaphlaxis several days later.
Could the second life-threatening event be due to a build up of the 2 toxins?
Many countries like India have recently announced the cancellation of the school annual examinations and promoting almost all the students without any examination due to the increasing COVID 19 pandemic spread. Though the reason for this step is very clear and right on the part of the government who is seeking the safety of students first, do you think that this step will adversely affect the future education pattern of these students?
I am trying to publish an only moderately novel paper in COVID19 detection using transfer learning methods. I wish to publish it free of charge (possibly non-open access option).
Which journal(s) would you recommend for that purpose?
Thank you in advance for your suggestions.
The SDG7 seeks to ensure access to clean, affordable and sustainable energy for all. The fuelwood crisis in the 70s/80s was triggered by the Arab-Israeli War (the 1973/4 oil crisis) when astronomical increases in prices of petroleum products especially LPG led to a dramatic increase in the demand for cheaper cooking fuels such as firewood and charcoal. The COVID 19 pandemic coupled with the Russia Ukraine war has sparked another global energy crisis similar to what happened in the 70s. Is another fuelwood crisis looming? If yes what can be done to prevent it?
Dear: Does infection with Covid 19 stimulate cancer cells, especially breast cancer? Is there any research in this field?
One of the women, at the age of more than fifty-five years, had a fracture of the spine, and it was later revealed as a result of the diagnosis that she had breast cancer, and it developed towards the lymph nodes and then the spine. Is there research in this area and what is the relationship of cancer to broken bones of the back vertebrae? Is there a cure for such injuries?
Some recent studies have documented COVID-19 being zoonotic. Online documents show china testing fish for the coronavirus. How ever, pets such as cats and dogs rarely show the signs of the disease even after infection, though there can still shed the virus to humans. To this effect, what preventive recommendation should be done against transmission of the virus between pets and humans. Is it possible fo the vaccine administered to humans also be administered to pets?
Before submitting a paper work to a journal, knowing its reputability is important.
What we look at to identify whether a journal is reputable or not? If two journals are reputable, is/are there way/s of selecting the better one?
would like to learn more about appropriate material for the application of PPE in Epidemiology.
As all the material seems to be Polyethylene/Polypropylene, would love to learn, whether it is possible to use Polyamide material instead? Are the properties sufficient?
If Polyamide does the job, are normal Snowboarding and Fishing Overalls an alternative to the ordinary Hazmats?
Cherish your feedback.
Covid-19 spread from outbreak to pandemic due to movement of patients from affected area in early time of disease. Is mismanagement/mishandling lead the disease from an outbreak to pandemic.
Legacy of >340,000 dead as of 23 May 2020 & expected another 300,000 deaths in this yr: Should humans still be fond of bush meats? Keep giving a damn to the so-called restoration of the environment & biodiversity; issues of carbon emission & greenhouse effects; health & disease research? Calm to remain busy with war or peace? Going beyond an instinct or abide by judgment, & rationale? Assailing or defend each other?
The COVID 19 pandemic coupled with the Russia Ukraine war has disrupted global supply chains and negatively affected global economic growth with Agriculture and industry sectors being the worst affected. The fundamental question arising is,
Should the SDGs be revised to reflect current realities?
The Monkeypox is a viral zoonosis with symptoms similar to those seen in the past in smallpox patients. According to WHO Monkeypox is usually a self-limited disease with the symptoms lasting from 2 to 4 weeks, but severe cases can occur. Recently, the case fatality ratio has been around 3–6%. The association with transmission is more limited to cases related to homosexual patients, can it be a more limited spectrum indication? In this way, the public health advice for gay, bisexual and other men who have sex with men is the main point to be addressed? Or should we learn more from other Monkeybox outbreaks? Should the care applied to the COVID-19 pandemic be useful in this case, for example? It's something new (at least for the current variant) and one that has caused great distress especially after the traumatic worst phase of the COVID-19 pandemic. The WHO recommendations have been assertive and very coherent, therefore, in the progress of current studies we should have more answers, but the question for simple discussion remains in the air: Is Monkeypox outbreak that dangerous or is there not enough data yet?
What are some of the effective tools and leadership techniques that you have used to actively engage your students during the pandemic times? Did you find the tools you were using before the lockdown useful and do you plan to continue using them or you intend to change to a more effective tool?
When we talk about Post COVID Syndrome, we are referring to many symptoms that may have continued after suffering from COVID19, or that have occurred up to 1 year later. Are communication and non-verbal oral functions in this same bag?
What is clearer is the question of water quality in terms of qualitative characteristics, whether or not they change?
There is evidence that certain viral diseases (for instance, AIDS/HIV infection) decline our immunity and make us vulnerable to other diseases. Similarly, Does COVID-19 may have a negative impact on our immune strength against other diseases?
Due to COVID virus most of the human beings are facing lot of difficulties from past two years. The COVID virus also changing its structure continually and affecting human beings. To destroy the COVID or any virus present in a isolated room I have invented an Air Purifier with incorporating various techniques and I have tested the same with bacteria capturing. I have found the air purifier is working effectively for Bacteria capturing. Know I want to study further the efficiency of air purifier in terms of virus capturing. In this study I want to collaborate with various experts in the same filed. The interested can message me to discuss further details.
I want to better understand the difference between efficacy and efficiency to be able to compare the effectivity of various COVID-19 vaccines by using the vaccines' efficacy and efficiency.
All protocols of RT-qPCR to detect SARS-CoV-2 uses more than 1 gene to detect this virus (I am not talking about the internal controls). Why this gene cannot be used alone?
There are many papers related to Covid-19 on preprint servers. Most of which are not reviewed. This is particularly more so in computational studies such as Virtual screening, docking and molecular dynamics.
What is the general consensus of the scientific community regarding referencing this studies?
In the current COVID-19 crisis more than 380 thousand people died so far. Economy and mental health suffered tremendously. If there was an easy solution proposed in the very early stages of the crisis based on scientific findings by any scientist what would be the right course of action for other scientists and people in power of position?
1) Ignore that important solution and wait for the actual peer-review process to be completed. 2) Take initiatives individually and collectively on an emergency basis to explore the potential research and solution further. As saving lives are of absolute priority, a single day should not be wasted. 3) Resist that research and solution, as it is non-mainstream area and stop by any means even to send that research for the peer-reviewing process.
Which one do you agree with the most and which one the least? To improve, what action needs to be taken in either case?
Because of international threat of covid v-19 and spread of disease to the the degree of closing many countries and delay in the economic regain ,millions of peoples in America,russia ,india ,spain ,and euoropean countries all suffer alot ,So how to give them the basic information for the epidemic and anything about syptoms,and treatment?
I'm working on a set-up for COVID-19 RNA extraction, and Sodium citrate is needed in the protocol for lysis buffer and precipitation buffer. Do you know any alternative for sodium citrate that can be applied in COVID-19 RNA extraction?
A patient with desminopathy survived Covid-19 six months ago without pneumonia, but with a temporary loss of smell and taste. After Covid-19, we note an accelerated progression of desminopathy, penetration accelerates, new muscles are quickly involved in the pathological process, muscle mass decreases, and heart function worsens. Perhaps the infection or its consequences are somehow connected with the mechanism of progression of desminopathy?
Elective procedures were temporarily suspended several times over the course of the pandemic of COVID-19 worldwide. In Brazil, there was a reduction of 46% in the number of elective procedures carried out in the public health system in the first 9-month of the COVID-19 pandemic (please see the paper below).
Although it is a pressing issue in Brazil, the government seems to not have a planning for the recovery of elective procedures in the country. What about other countries? What actions have been implemented?
A basic understanding of atomic structure under the new insight may help the COVID-19 community in its formation mechanism and extermination mechanism. I feel that these articles can be helpful in understanding the basic mechanism of formation (development and growth) of COVID-19, so in its elimination and extermination, and more specifically in the evolution of shape (morphology) and its structure. (The links provided for the articles are in non-peer reviewed form but these are in final version from the author’s side.)
(The links provided for the articles are in peer reviewed/published form.)
It seems to be transmitted by rodents. As we know, sewer mains are habitat for rats which frequent cities. Thus, there is a question of transmission prior to the raw sewage reaching the wastewater treatment plant. Thus, there is a question of the pox virus surviving the treatment process. It has been proposed that SARS-CoV-2 can be picked up by fecal bacteria as lysogens, is the Monkeypox able to also do this? If rats (rodents) can carry this, is there any chance of also carrying both Monkeypox and SARS-CoV-2 and a reassortment?
Dr Edo McGowan
Hi, my data has coordinates ( x and y) at district level, dates and daily covid cases on that particular date (not daily total cases). What can i do with the data? i have done spatiotemporal analysis but not sure if it's correct. I dont have access to do the Arcgis pro tutorial. i want to do hot spot and prediction of coming hot spot but how can i do it with this same coordinates which has different time only.
In this era of COVID-19 pandemic, every government in each country and territory of the world is doing its best to have a victory over the COVID-19 multisectoral crisis. With the presence of such countless multidirectional negative impact of COVID-19, still all recommendations from Nationals, Regionals, and International setups including WHO focuses on transmission-based precautions. Transmission-based precaution could be highly successful if all features of COVID-19 are identified completely, but it is not yet so far. Hence, why standard-based precaution is not recommended as part of public health measures against COVID-19 globally?
For a research on a psychotherapeutic intervention for health care employees in the face of COVID-19 I am looking for the Nursing Stress Scale or a similar instrument to measure stress in nursing-staff. It would be great if anyone could help me.
Thank you :)
Traditional construction of research knowledge in master and doctoral thesis programmes / modules mostly comes from close interactions between research students and their supervisors. Most master and doctoral theses have sharp research foci. Post-doctoral research publications based on the research works might take longer time to be completed after graduation, if students rely fully on their supervisors’ further guidance.
Luckily, some supportive or generous master or doctoral supervisors will help co-publish some journal papers with their research students, based on the thesis contents. Yet post-doctoral research works might not easily be offered under the same supervisors or the same universities. Without high-quality research publications, current young scholars ('baby-doctors') suffer badly from getting some post-doctoral scholarship or funded post-doctoral research projects, facing local and global keen competitions. Currently, mere doctoral degree cannot help much in most employment situations after graduation. Therefore, vacant post-doctoral teaching / researching job posts cannot be easily offered by universities or other higher education bodies in their own countries to young scholars after getting their doctoral degrees or even completing their postdoctoral studies in the slowly recovered local or international economic systems, especially under the violent attack of the COVID-19 pandemic.
To what extent can we (as university professors and lecturers) help remedy such situation, especially facing shortage of research fund? Any suggestions offered to our young scholars in local, international and global contexts?
The US CDC knew very early, from post-marketing Adverse Reaction reports, that the COVID-19 vaccines were causing numerous Amyloid fibril diseases including Amyloidosis subcategories: Cerebral angiopathy, Senile, Cardiac, Cutaneous, Dialysis, Hepatic, Pulmonary and Renal.
Elegant work by Swedish researchers demonstrated that Synthetic Spike Protein can be broken down in vitro by incubation with the protease Neutrophil Elastase into short peptide sequences that can induce damaging amyloid-like fibrils.
References: Vaccine Adverse Event Reporting System (VAERS) Standard Operating Procedures for COVID-19 (as of 29 January 2021)
Coronavirus disease (COVID-19) pandemic is a global health problem. Infected patients usually have respiratory symptoms due to lung involvements. However, liver impairments could be another findings.
So does Covid-19 affect liver functions & how?
The rapidly unfolding uncertainties caused by the COVID-19 pandemic to governments, business organisations, communities and individuals has necessitated the putting into place a set of economically mitigating measures to avert a deeper scarring to lives and livelihoods. Such measures often include furloughing employees, which means a temporary laying off of millions of employees in both developed and developing economies as a way to protect businesses from going under.
However, as some governments have started intimating that such an unprecedented move is time-restricted and that the acquired debt would have to be repaid from some other tax increases, promotion and recruitment freezes or austerity, a fundamental question needs to be asked within employment studies. Others may opine that longer-term and more sustainable strategies are needed as we are still uncertain as to how long this pandemic may last.
Therefore, the question for this discussion is 'should governments and businesses around the world furlough or not furlough staff?'
Based on the topics listed in https://www.nature.com/articles/d41586-020-03564-y the diversity of major topics categories under which research publications on COVID are grouped are:
- Modelling epidemic, controlling spread
- Public health
- Diagnostics, testing
- Mental health
- Hospital mortality
It is obvious that Lateral Flow testing belongs to the third category on the list - diagnostics/testing. The software interface aspect of things is not addressed. One aspect that would belong to the software side is the reporting/registration of results. Please read the latest preprint of my paper on this subject at:
What are your thoughts on the impact on our preparedness for serious pandemics if software engineers develop methods to tackle online cheating at home? Please share your thoughts, let me know if I can quote you as a reviewer for this paper in a journal. Thanks in advance for your collaboration.
How sociologists can involve the study of Impact on COVID-19 in the marginalised communities in India?
Phil Davis, a bibliometric expert wrote when Lancet took the 2021/2022 impact factor lead:
"No discovery or invention in the history of science can come close to the effect COVID-19 papers had on the citation record in 2021. However, because the Impact Factor is so sensitive to highly cited papers, some journal scores will reach stratospheric heights this year, only to collapse next year. Unfortunately, this super-charged cycle of boom and bust is only going to fuel a greater sense of skepticism around the meaning and interpretation of the Impact Factor".
Will this come to pass, or to be construed an opinion that holds no water?
Temporal evolution of externally injected ‘VACCINE’ (similar to the external injection of chemicals used in chemical EOR) against internally ‘Mutating Residual-Virus’ (similar to the residual oil saturation within a reservoir): Vaccine Effectiveness remains far away from efficacy?
How does our body metabolism (similar to basic reservoir rock/fluid properties and rock/fluid interaction) – in general - gets altered following exposure to COVID19 (say, similar to formation damage)?
Why and how does the Mutating Residual Virus significantly influencing our circadian rhythms (similar to the way the capillary pressure influencing the relative wettability)?
What is the attached time-scale - over which – the SARS-CoV-2 vaccine efficiency and effectiveness - against COVID19 – gets waned over time (the way, the porosity and permeability getting reduced with time and subsequently reducing the reservoir efficiency due to various factors)?
How protective is the vaccine efficiency and effectiveness – against COVID19 – irrespective of age, types of vaccines, types of variants & local ambience (say, how efficient a proposed EOR process could be irrespective of reservoir heterogeneity)?
I am aware of GISAID but I can only find the full original Wuhan strain and amino acid mutations in the Spike protein for BA.4 and BA.5. Does GISAID share mutations in other regions of SARS CoV 2's genome?
Edit: clarified whether the mutations in the S protein are Nucleotide or Amino Acid
Hi. I am validating one Covid 19 kit and covering different labs. I mainly used Quant studio 5 & 7 and Biorad CFX 1000 touch( qPCR machines).
My kit validation has passed from many labs but from one lab I am getting too much Invalids(even after several reruns with some variations). However, procedure and conditions are same in all labs. How to resolve this?
Only thing remaining to retest that Staff used "White plate" but they run the program for the "Transprent plate ". Does it make the result invalid / No IC?
As many of the people are showing interest towards in joining for Bachelor, Masters, Ph.D. and certificate-based programs in "Abroad", Is COVID-19 will effect on the future education system? If they are not interested to join into the Universities, what about technology development and sources of income generation?
Did the products & services changed after COVID-19?
Is the service quality the most important aspect to aim for after COVID- 19 ?
Is it the ‘Social media’ that counts ?
or Delivering affordable prices with lower standards for the people who can’t afford buying high prices products? ( or targeting niche markets only)?
Whether the sub-variants of Omicron strain still remain infectious? Is it not uncommon for a natural virus?
To what extent, the immunity levels have been retained following the COVID19 vaccination doses?
Whether retaining the immunity levels would always require pandemic restrictions? Whether in the absence of pandemic restrictions – seasonal respiratory viruses could play a crucial role?
When will we have enough data on vaccine response – that would probably tell us on – whether – how much the sub-variants will be able to mitigate the protection from hospital admission?
To what extent, are we technically advanced in order to figure out the new mutations and even in such cases, how fast will we be able to react both medically as well as socially?
What is to be understood – when a triple-jabbed person (in the absence of co-morbidities) gets infected again?
Feasible to eliminate the virus completely from our system (body) – once we get infected with COVID19? To what extent, the ‘residual virus’ could infect – in the long run?