Science topic
CNS Demyelinating Autoimmune Diseases - Science topic
CNS Demyelinating Autoimmune Diseases are conditions characterized by loss or dysfunction of myelin (see MYELIN SHEATH) in the brain, spinal cord, or optic nerves secondary to autoimmune mediated processes. This may take the form of a humoral or cellular immune response directed toward myelin or OLIGODENDROGLIA associated autoantigens.
Questions related to CNS Demyelinating Autoimmune Diseases
Is it FTY720 specific to humans or it can be used to treat EAE in mice as a control positive ?
I have read about multiple sclerosis and I was very surprized that no medication is available for this disease!
Mayo Clinic stated " There's no cure for multiple sclerosis. However, treatments can help speed recovery from attacks, modify the course of the disease and manage symptoms"
Is it true? Which drugs are recommended for this condition?
We are finding a significant role of neuro invasive viruses in the instigation and promotion of the Multiple Sclerosis. Is there any other scientist out there who has already conducted some research work on this subject?
Macrophages are known to be an active player in MS. They are involved in active demyelination and myeline uptake, which leads towards the development of foamy macrophages with M2-like properties. But can they migrate out of the brain/lesion before they become necrotic and cause a pro-inflammatory respons (cfr. atherosclerosis)?
Wants to compare actual treatments of Secondary progressive