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Business Process Optimization - Science topic

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Background of the problem for people non familiar with transfusion:
Every day, hospital transfusion services must guarantee they have enough blood to meet patient transfusion demand. This is very like managing a food stock in a refrigerator but even easier (just one product, one expiration date).
Assumptions:
- RBC (red blood cell) units are kept on a refrigerator with enough capacity
- Maximum expiration date for RBC is 42 days.
- We make a routine order to the blood bank provider (our grocery store) every day from Monday to Friday. We can make additional orders if we run out of stock.
- We practice first in first out.
The model should satisfy the following targets:
- Minimize the expiration rate (the number of RBC units expiring every certain time)
- The less time on the refrigerator the better (eat fresh)
- Avoid extraordinary orders as much as possible (some extraordinary order might be considered to cope with transfusion peaks of demand)
- Note: I have purposely simplified the problem (no considerations of ABO group distribution, crossmatched reserved units, or reduced expiration date of the irradiated blood…).
Non controlled external factors:
- Transfusion rate
- Average remaining time to expiration of the received blood.
What we are looking for is the optimal number of RBC units we must order on a routine basis (M-F) which is the only factor we can adjust to optimize the equation. Resulting figure must be recalculated when transfusion rate or average expiration date of the received units change.
Intuitively, I see how the number of extraordinary orders and RBC freshness are at opposite sides of a balance, because if a higher number of extraordinary orders is tolerated, then it should result in a smaller but fresher RBC inventory. On the other hand, in order to avoid extraordinary orders, you need a greater inventory thus increasing the average age of your products and the risk of expiration.
Any idea or suggestion? Any available script on Excel/SPSS/Stata/R/SQL? Any related bibliography?
I can provide raw data for simulations on demand if someone want to make a collaboration.
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good work
Interested
best of luck
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I am looking for a database of similar business processes (or even better - a configurable processes) in BPMN format.
I need this to evaluate a recommendation algorithm for designing BP that uses machine learning approach and hence needs a lot of learning data.
That's why I am especially interested in a large database of similar processes, or configurable processes.
I would appreciate your help.
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BPM Academic Initiative (BPMAI) dataset : https://zenodo.org/record/3758705#.XrZDamgzbDc
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As Project management is a very big topic my focus is on the process from initialization to the end of a particular Task / Project in company working globally and what are the challenges they face in handling it. But i am not sure about the content or researches i have to do or what new i can do in this field ?
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Dear Abhishek, you could check the latest issues of project management journals and topics at PM conferences to see what are current topics of interest in the field. From that develop an own idea. You could take examples of internationally working organisations or even try to get a topic directly from such organisation. I personally think that knowledge management in international projects is a very interesting topic and is worth further research.
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Do you have practical experience with ABPM?
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Thanks Amina. The changes made in the case I described above proceeded both iteratively (we worked through all the logic three times, and some areas even more than that) but some of the most significant changes were made even as the initial model was recorded. That seemed pretty much inevitable, as the need for change was recognised immediately, so changes were made between discovery sessions.  But once we completed the first pass right through, we realised that we had to review what we had done to take account of further improvements that then became obvious. As far as I am concerned, that is the essence of Agile.
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Business process Re-engineering is considered as an obsolete subject as it was considered as another name for re-sizing the organization and was also based on clean slate approach.
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Business Process Re-engineering is considered as an obsolete subject as it was based on processes optimization without considering humans. Business Process Management is now a days a broader concept, integrating processes, humans and IT.
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I am looking for SOP's, Workflows, best practises and so on. This is to support several SME's and develop softwares for them accordingly.
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You can have a look at the (Open) process handbook developed by the MIT. The handbook database can be accessed through a dedicated tool, which is freely available from the project website http://ccs.mit.edu/ophi/index.htm.
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To get information system flexibility, we have to decompose Business Processes (BP) to small units that can be replaced with other ones. These units are Business Services (BS). So how we can obtain these BS?
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LEGO (R) is a good comparison or metaphor:
Your process models are the LEGO sets (or individual LEGO constructions), each composed of different LEGO bricks (your business services). How did LEGO decompose to maximize reuse, replaceability and flexibility? The LEGO nops are the secret. We call it the business object model for the application domain. Without the nops you need many adapters and/or glue, which reduces flexibility and reuse.
The shapes of most bricks (their interfaces) need to be regular, but additionally you need special purpose bricks for special applications. For services of course their semantics is an additional dimension, not covered by the LEGO metaphor.
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I'm looking for the most appropriate modeling methodology to understand how disruptions will affect a supply-chain system.
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Dear Christopher you suggestion have been helpful. I'll check the Moebius manual. Many thanks!.