Questions related to Brain Mapping
I am interested in a mouse model of a controlled cortical impact that would mimic sports concussions by creating a mild TBI without any incisions, but I'd like to try and create specific coordinates and target specific brain areas. I figured I could use the eye as a landmark to find Bregma, but I can't seem to find an atlas for the head like you'd find for the brain or skull. Is there a reference for the average mouse skull size with measurements like the mouse brain atlas, or another effective landmark for locating Bregma without creating an incision?
could anyone point me to papers comparing different masks/atlases for a particular brain region? I couldn't seem to find anything and I'm interested in different methods used for the comparison. The paper doesn't need to be specifically dedicated to the comparison, even if it is mentioned somewhere in the discussion it would be helpful. Thank you in advance!
Does anyone know how to mark the specific brain region in immunofluorescence brain slides of mice via mice brain map? the Allen brain atlas can't precisely describe the information of individual slides, and the black background of immunofluorescence brain slides seems disharmony when combined with the white background of the map from the Allen brain atlas, if there are a proper way to improve above problems, I would appreciate it if anyone can response to this question.
I have EEG signals and it has a few channels. Now, I want to plot the data in order to get the Brain Activity Mapping. It will be very helpful if anyone can give some idea to do it.
Thanks for your time and consideration.
How nanowire Field Effect Transistor sensors enable highly sensitive detection of biomolecule? Can we use use nanowire electronic devices for cell network mapping and brain mapping?
Looking for information on Clinical Neuropsychology Postdoctoral positions that focuses on Pre/ Intraoperative/ Post-Operative Brain Mapping and Cortical Stimulation in the United States / France/ Europe/ Australia.
Also looking for information on Centers/ Hospitals and names of Clinical Neuropsychologist who routinely perform these protocols (Brain Mapping and Cortical Stimulation) for Awake Brain Surgeries in US, France/ Europe and Australia.
Any information on any of the above would be greatly appreciated.
What are temporal limits in determining brain metastability? In other words, how long does the minimum length of the scan segment using fMRI have to be for the result to be of any value?
I'm particularly interested in measuring metastability during decision making. If I have two different decision conditions, which are shown alternately in the fMRI paradigm (so let's say condition A and B, and paradigm look like it: ABABABAB....), will "slicing" the data and combining them later produce reliable results in the context of metastability estimation (so I could calculate metastability for A and B condition separately)?
I came across a publication where a similar operation was performed (Alderson, TH, Bokde, AL, Kelso, JS, Maguire, L. and Coyle, D., 2020. Metastable neural dynamics underlies cognitive performance across multiple behavioral paradigms. Human brain mapping, 41 ( 12), pp. 3212-3234.). However, it concerned cutting out fixation elements between trials and joining whole blocks. I, on the other hand, want to cut and join the trials, then compare the level of metastability between the two conditions. Is it possible, or not really good idea?
I want to start research regarding Brain dominance and some concepts of positive psychology. That is why I ask whether or not it is a research area that is relevant now. If not could you please suggest what is a better fit to research on?
There are several cognitive challenges even a normal person can face (ref. Barbara Arrowsmith, "the woman who changed her brain"). How frequently are brain scans being used in common domains (not research-related) to detect these?
I need to look for brain rat regions activation after a certain stimulus made to live animals. The marker to be looking for needs to be maintained fro long periods because the stimulus that I need to give it promotes alteration with days of exposure. I don't have any imaging technique available.
i'm searching for free software which is able to visualize eeg-data in realtime in form of heatmaps (qeeg / brain mapping). Do you know any by change?
Thank you very much in advance
I am interested in scaling my coordinates for stereotaxic injections by measuring the distance from bregma to lamda in each of my mice and then scaling this to the "typical" value used in mouse brain atlases. This scaling factor should reduce some error that results from differences in mouse brain sizes. I would be most interested in knowing the bregma-lamda distance in the "average" or "typical" mouse used to map brain coordinates in the Paxinos Mouse Brain Atlas. Does anyone know this value? I see other people have used this method successfully in rats, where the Bregma-Lamda distance is 9mm.
I want to look at all the various brain regions and also the ascending and descending tracts from the brain, and make sense of the information flow.
Are you familiar with any studies on the amount of language switching (code switching, language mixing , or both) on the organization of languages in the brain?
Are cognitive control and cognitive effort the same thing?
I am confused. In the neuroscientific literature on second language learning, the neural organization of cognitive control and cognitive effort seems to overlap (e.g., the anterior cingulate, dorsolateral prefrontal cortex, inferior parietal regions). At the same time, I have come across some results that make me think that cognitive control and cognitive effort are not the same thing.
For instance, I have found fMRI studies that reported increased "cognitive effort" (and therefore more widespread fMRI activation) in less proficient speakers of a second language (e.g., Abutalebi et al. 2018). At the same time, several ERP studies have suggested more "cognitive/language control" in highly proficient second language users. For example, Fernandez et al. (2013) have shown that higher second language proficiency was associated with a greater mean N2 amplitude (greater inhibition) on an executive function test. Another example: Rossi et al (2018) concluded that individuals with high second language proficiency require more cognitive/language control for their first language, even before they speak their second language.
I will greatly appreciate your help.
With my best wishes,
I would appreciate it if someone explains the basic physical principles underlying the differences in appearance (image content, and tissue differentiation) among T1, T2, and PD weighted images.
I want to create separate masks for right and left hemispheres of the following regions:
ventro medial prefrontal ctx (vmPFC), dorso medial prefrontal ctx dmPFC), anterior middle cingulate ctx (mACC), posterior cingulate (PCC), precuneus (PC), inferior parietal lobule (IPL) and hippocampus (in parts if possble).
Any advice on which FSL atlas I could use greatly appreciated
We learn every day more and more about the way humans work by examining maps of the brain, and which parts are involved with various activities. There are a number of discussions on RG right now in which the question of whether or how animals' thought and reasoned behavior arises.
So who out there is involved in studies of animals' brains to try to determine answers to these sorts of questions?
Greetings everyone. I am just trying to figure out how routinely intraoperative neuropsychological and brain mapping protocols are performed at highly specialised neurosurgical units/ centres . Please do feel free to share where were you trained to competently carry out these advance protocols? And what are the usual techniques/ protocols that you perform?
Hi, we are currently working on the functional connectivity study where we would like to address the connections between thalamus and auditory cortex in patients and controls. What could be the most accurate tool for segmenting/masking of the thalamic nuclei? Does anyone has an experience with digital Morel atlas?
I have been using VBM8 in SPM12 for a few months now for volumetric analysis of the human Hippocampus, between two different groups. I'm completely aware that depending of the kind of modulation you apply to your data (affine vs non-linear) the different results you get. But in terms of correctness I didn't expect such a huge difference. Using the prior one (affine) and literately following the VBM8 manual I achieve very strange results being quite contradictory in comparison to the last named procedure. The major set-up difference between those two is the affine vs the non-linear selection and using the head size as covariate only for the affine method.
I have been thinking the possibility that this huge difference could be due to my contrast matrix being [-1 1 0 0 0] vs [-1 1 0 0] for the affine and non-linear method respectively. But it looks to be right for the two sample test as I have two groups and three covariates (age, head size (only for the affine) and HAMD.
I would appreciate if any of you could make this clear to me.
Thank you in advance!
Best regards; Cecilio.
Does thinking from the left or right side of the brain have an effect on the electrical activity of the brain?
In fact, I am have a good struggling with coinjection of fluorogold &BDA in the same brain region. My protocol for this combination is quite similar to which L. Swanson reported in PNAS, 2010 (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930585/), but with smaller injection current (+1-2 µA) and longer injection time (15-20 min). I can, however, get barely BDA labelled neurons or dendrites, but always very nice retrograde FG labelled cell bodies.
I almost always oberseve FG gets precipitated, especially up to first 5mm of glass pipette from its tip. I consider this might be a reason for a lack of BDA labeling in my case.
Any suggestions or comments? Thanks in advance!
I am desperatly searching for an app or tool or software solution to create a density plot in kinds of a heat map (see example). I want to depict frequencies of answers (better mappings) of patients in a graphical question (body scheme). These answers are provided on paper - thus there are two problems: an aquisitional (input) and a graphical (output).
My conception would be a tool which can import the picture pattern (body scheme). Thereafter for data aquisiton I want to click on (previously defined) area(s) where the patients put their cross(es) - For the output, the tool shall provide a dataset with the coordinates or areas and their frequencies depicted as color shades right over the picture pattern.
I want to quantify gross brain morphology observations/deviations in a chicken embryo model, so that I can run an ANOVA, instead of doing it qualitatively.
Thank you in advance for your help.
For a computational model of the rat-hippocampus I would like to better understand how the projections from the entorhinal cortex to the hippocampus looks like. I think, data obtained with CLARITY-method would be the best for my needs. Does anybody have volumetric data of the rat hippocampus and adjacent regions that he could share with me?
- It would be interesting to know if a polyglot would have similar or entirely different perceptions, since what appear to be "nonsensical" letter strings in an idiom might be more familiar, from the visual standpoint, in another idiom - so that what appears to be nonsensical to, say, a native Portuguese speaking who was iliterate in German or French might suggest sounds or words to another who was literate in that idiom.
- From another standpoint, I wonder what makes a set of characteers familiar or nonsensicle. A native russian (not literate in other idioms) might perceive a string in latin characters as nonsensicle and even fail to integrate the perception of latin charachters, while the reverse would be the case for non-russian people. Someone who´s multilingual might have a different, more integrated perception of both characters sets. Even stronger effects would be observed as to Japanese / Chinese people, where the character sets are strongly visual, symbolic, and might be more associative. Would a chinese react similarly to a set of Japanese characters, and differently to a set of latin charachters? Would a Russian have similar reactions as to other similar ciryllic characters, in other baltic idioms?
- Could the "literacy area of the brain" be thus mapped?
- Just wondering...
I have a 64 gradient plus 5 B0s DTI dataset and need to remove some intermediate volumes (ie. volumes number 10, 23, 35, 55). In fact I have a software that requires all the B0s to be at the beginning of the study, and a dataset where the B0s are distributed through the acquisition. How can I do this? Can I use Matlab? Could you suggest me the correct procedure? Alternatively I need to move the same volumes so that they all end up at the beginning of the volumes sequence.
Perhaps by using a box or sphere, centred around particular coordinates, or using anatomical features as boundaries?