Blood Vessels - Science topic

Retinopathy is a progressive and common retinal disease that most progressive diabetics suffer from and causes blood vessels in the retina to swell and leak blood and fluid. This condition requires timely diagnosis via medical experts to prevent causing visual loss among patients. To enhance the feasibility of checking many persons, diverse deep-le...

In endovascular therapy, the induction and stable placement of the guiding catheter (GC) are not only the initial steps but also crucial techniques influencing treatment success. However, in some cases, GC induction is challenging due to variations in the aortic arch or tortuosity of the blood vessels. In the present case, endovascular therapy was...

In Japan, the number of autopsies has steadily decreased. Therefore, postmortem imaging methods have positioned as valuable supplemental or complementary tools in autopsy procedures. We clinicians are increasingly faced with the need to infer cause of death from postmortem imaging findings. We report computed tomography (CT) and magnetic resonance...

Rotation advancement flaps are a challenge for dermatosurgery and in particular the severe clinical cases, mainly affecting skin tumors in the facial area or the so-called ˝high risk areas˝. The proximity of these areas to important vital structures (such as nerves and blood vessels) also determines the need for more precision when performing this...

Coronary artery disease (CAD) is a life-threatening condition caused by the chronic gradual narrowing of the lumen of the blood vessels of the heart by atherosclerotic plaque with a strong genetic component. The aim of our study was to investigate the association between the VEGFA polymorphism rs2010963 and myocardial infarction in patients with ty...

Stroke is a major global health concern, with 12.2 million new cases and 6.6 million deaths reported in 2019, making it the second leading cause of death and third leading cause of disability worldwide. Ischemic stroke, caused by blood vessel occlusion, accounts for 87% of stroke cases and results in neuronal death due to oxygen and nutrient depriv...

This study aims to examine the potential of flavonoid antioxidants found in dragon fruit peel (Selenicereus undatus) in supporting cardiovascular health. Flavonoids, as bioactive compounds with antioxidant properties, have an important role in protecting the body from oxidative stress that can damage cells and tissues, including the cardiovascular...

Background The interaction between the metastatic microenvironment and tumor cells plays an important role in metastatic tumor formation. Platelets play pivotal roles in hematogenous cancer metastasis through tumor cell‐platelet interaction in blood vessels. Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy distinguished by its...

Diabetic Neuropathy is a damaging of Nervous system associated with Diabetes Mellitus. It occurs due to microvascular injury involving small blood vessels in addition to macrovascular conditions with a prevalence rate of almost 50% in individual with long standing type 1 and type2 Diabetes[1]. Symptoms may include tingling sensation, numbness, burn...

Photothermal therapy (PTT) is widely used in wound healing because it produces heat under near‐infrared irradiation, eliminating bacterial infections. However, excessive production of reactive oxygen species (ROS) occurs during PTT, which causes oxidative stress damage. In this study, a nanozyme, PDA‐MnO2 (PM), is synthesized and encapsulated in th...

Diabetic retinopathy stands as a significant concern for individuals managing diabetes. It is a severe eye condition that targets the delicate blood vessels within the retina. As it advances, it can inflict severe vision impairment or complete blindness in extreme cases. Regular eye examinations are vital for individuals with diabetes to detect abn...

The present study was conducted on 10 tongues of recently dead adult camels (Camelus dromedarius), irrespective to age and sex, who were free from any pathological condition of tongue. Histologically, the tongue of camel consisted of mucosa, muscle layers, glands, blood vessels and nerves. The mucosa consisted of keratinised stratified squamous epi...

Vascular aging refers to a series of processes where the elasticity of blood vessels diminishes, leading to stiffening, and deposition of fat components on the vessel walls, causing inflammation. Cardiovascular diseases, such as stroke and hypertension, play significant roles in morbidity and mortality rates among the elderly population. In this st...

s Vascular compression of the facial nerve is a well recognized cause of hemifacial spssm (HFS). Magnetic resonance imaging (MRI) and magnetic resonance angiog-raphy (MRA) provide vascular and brain tissue diagnosis in a single non-invasive examination and should be recommended as primary neuroradiological procedure in HFS. We report a rare case of...

Introduction Magnetic nanoparticles (MNPs), particularly iron oxide nanoparticles (IONPs), are renowned for their superparamagnetic behavior, allowing precise control under external magnetic fields. This characteristic makes them ideal for biomedical applications, including diagnostics and drug delivery. Superparamagnetic IONPs, which exhibit magne...

Background The presence of a human tail is a rare condition resulting from an embryonic remnant that fits the definition of a caudal appendage. It may be a vestigial (true) or a pseudotail. Both may be considered markers of underlying intraspinal abnormalities. Case Description The present case documents a 5-year-old girl with a caudal appendage i...

Intracerebral blood volume changes along the cardiac cycle cause volumetric strain in brain tissue, measurable with displacement encoding with stimulated echoes (DENSE) magnetic resonance imaging. Individual volumetric strain maps show compressing and expanding voxels, raising the question whether systolic compressions reflect a physiological pheno...

The main object of this paper is colorectal cancer (CRC). Colorectal cancer is a malignant tumor that occurs in the colon or rectum. It is one of the most common cancers in the digestive system in the world. Its pathogenesis is complex and is related to many factors, including genetic factors and lifestyle habits. Mild cases can be treated and have...

There is no doubt that the proper development of the heart is important for its correct function, in addition, maturation processes of the heart are crucial as well. The actin-binding protein nexilin seems to take over central roles in the latter processes, as nexilin-deficient mice are phenotypically inconspicuous at birth but die within short tim...

Shadow artifacts caused by high scattering of the superficial vessels will cause structural and vascular discontinuities in optical coherence tomography (OCT) images. Large blood vessels can cause more severe shadows, leading to clinical misinterpretations. Traditional sequence-based methods for inpainting shadowed regions meet challenges in dealin...

Tartrazine (E102) is a controversial coloring agent whose potential impacts on human health are not fully understood. Our study reveals the vascular disrupting effects of tartrazine (TTZ) on developing zebrafish embryos in vivo and on human umbilical vein endothelial cells in vitro. The dye was shown to cause dose-dependent hemorrhages in zebrafish...

The fabrication of force sensors is reported using ZnO/ZnMgO coaxial nanorod arrays grown on a titanium (Ti) wire and their application for force monitoring inside a blood vessel during catheterization procedures. The core‐shell nanorod arrays are grown using catalyst‐free metal–organic chemical vapor deposition (MOCVD), enabling precise control ov...

Speckle variance optical coherence tomography (SV-OCT) is a non-invasive imaging technique that can map blood flow in tissues by capturing speckle pattern variations from moving red blood cells. A key challenge of SV-OCT is distinguishing variance caused by blood flow from non-motion signals like shot noise. Here we show that noise contributions du...

Human cerebral blood vessels are highly intricate and significantly contribute to brain function support. In the surgical process of these vessels, the neurosurgeons will basically employ magnetic resonance imaging (MRI) as an imaging media to understand the location of the disorder, the anatomical position of vessels, and a guide in the surgical p...

Capillaroscopy is a non-invasive method of leading importance for the early diagnosis of progressive systemic sclerosis and other systemic rheumatic diseases with manifestations of Raynaud's phenomenon. Capillaroscopic changes in patients with occupational diseases are still scarce and poorly defined. Of interest is vibration disease, in which smal...

Numerous studies have demonstrated that pesticides are toxic and harmful to human, animal, and environmental health. Glyphosate is the most widely used herbicide globally. This research aimed to assess the impacts of various dosages of glyphosate on rabbits. A total of 30 rabbits were divided into four groups: one control group and three treatment...

Dieulafoy lesions are a rare cause of gastrointestinal bleeding, characterized by an enlarged submucosal blood vessel that bleeds without visible abnormalities. The diagnosis is typically made via endoscopy, and treatment usually involves endoscopic therapy. This case involves a 46-year-old female who presented with upper gastrointestinal bleeding...

Speckle variance optical coherence tomography (SV-OCT) is a non-invasive imaging technique that can map blood flow in tissues by capturing speckle pattern variations from moving red blood cells. A key challenge of SV-OCT is distinguishing variance caused by blood flow from non-motion signals like shot noise. Here we show that noise contributions du...

Background: Pulmonary embolism (PE), a common heart and blood vessel disease, causes complications such as haemodynamic instability and cardiovascular mortality. Timely diagnosis and treatment are imperative for managing this potentially life-threatening condition.Aim: The aim of this study was to establish the relationship between an elevated D-di...

Vascular calcification (VC) is a biological phenomenon characterized by an accumulation of calcium and phosphate deposits within the walls of blood vessels causing the loss of elasticity of the arterial walls. VC plays a crucial role in the incidence and progression of chronic kidney disease (CKD), leading to a significant increase in cardiovascula...

Background: Diabetic retinopathy (DR) is a major complication of diabetes mellitus (DM) that affects the blood vessels of the retina and cause vision loss and blindness. DR is a major public health problem worldwide, especially in low-and middle-income countries where access to screening and treatment is limited. Although Ethiopia has implemente...

Glycated hemoglobin (HbA1c) is the most important factor in diabetes control. Since HbA1c reflects the average blood glucose level over the preceding three months, it is unaffected by the patient's activity level or diet before the test. Noninvasive HbA1c measurement reduces both the pain and complications associated with fingertip piercing to coll...

Background Maxillary Schneiderian membrane (SM) perforation is one of the complications of maxillary sinus (MS) augmentation. The aim of the present study was to analyse cone beam computed tomography (CBCT) findings to identify prognostic factors for SM perforation. Materials and methods 50 CBCT scans were recruit for the analysis, 39 were suitabl...

Introduction Rosai-Dorfman Disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy, is an uncommon histiocytic disorder. It may be associated with autoimmune diseases, but there are few reports of concurrent ankylosing spondylitis. RDD is typically characterized by massive bilateral and painless cervical lymphadenopathy, which...

Physical activity has profound effects on the circulatory system, promoting cardiovascular health through various physiological adaptations. This review explores the acute and chronic impacts of exercise on the heart, blood vessels, and blood components. Acute effects include increased heart rate, cardiac output, and vascular resistance modulation,...

It is critical for the proper segmentation of blood vessels in retinal images that for the early diagnosis and continuous monitoring of many retinal diseases, including diabetic retinopathy, glaucoma, and age-related macular degeneration. The paper introduces a novel approach that combines the strengths of architectures in deep learning with tradit...

Age-related macular degeneration (AMD) is the most common cause of irreversible loss of central vision in elderly subjects, affecting men and women equally. It is a degenerative pathology that causes progressive damage to the macula, the central and most vital part of the retina. There are two forms of AMD depending on how the macula is damaged, dr...

Background: Changes in the positions of teeth occur during orthodontic treatment due to the application of forces that cause restructuring of the periodontal tissue. In the last decade, substantial research has been conducted to detect different biomarkers in the gingival crevicular fluid (GCF) to obtain a better assessment of the periodontal statu...

Stroke is a disease of a sudden acute decreased nerve function caused by disruption of the brain's blood vessels, causing signs and symptoms according to the area of ??the brain disorder. Stroke often causes residual symptoms such as movement, speech, and swallowing disorders. Therefore, it needs several efforts to prevent and control risk factors...

Head and neck cancer is the 7th most common malignancy worldwide. Few decades earlier, there has been an enormous rise in genetic events as the source in the development of Oral Squamous Cell Carcinoma (OSCC) and metastasis to various organs. The seeding of neoplastic cells occurs via blood vessels (haematogenous spread), lymphatics (lymphogenous s...

Diabetic Retinopathy is one of the most familiar diseases and is a diabetes complication that affects eyes. Initially, diabetic retinopathy may cause no symptoms or only mild vision problems. Eventually, it can cause blindness. So early detection of symptoms could help to avoid blindness. In this paper, we present some experiments on some features...

Vasculitis is defined as an inflammatory cell infiltration and destruction of blood vessels identified upon histologic examination. Cutaneous manifestations may be the first and only manifestation of the disease or be a part of a systemic condition. Cutaneous vasculitis (CV) affects small vessel (<50 μm) and medium (<50–150 μm) vessels located in t...

Nanoparticle (NP)-based drug delivery systems have received widespread attention due to the excellent physicochemical properties of nanomaterials. Different types of NPs such as lipid NPs, poly(lactic-co-glycolic) acid (PLGA) NPs, inorganic NPs (e.g., iron oxide and Au), carbon NPs (graphene and carbon nanodots), 2D nanomaterials, and biomimetic NP...

Mechanical solid stress plays a pivotal role in tumor progression and therapeutic response. Elevated solid stress compresses intratumoral blood vessels, leading to hypoperfusion, and hypoxia, which impair oxygen and drug delivery. These conditions hinder the efficacy of drugs and promote tumor progression and treatment resistance compromising thera...

Objective Sublingual varicose veins are variations of normality that appear more prominent during aging. The systematic review aim to investigate sublingual varicose veins frequency in patients exposed to systemic and environmental exposed factors linked to cardiovascular diseases. Methods This systematic review was based on the PECO strategy, and...

The need to investigate skin necrosis was never greater. Skin necrosis occurs when skin is acutely deprived of blood and oxygen for a prolonged period resulting in cellular and eventually tissue death, a process that often originates with peripheral arterial disease (PAD). PAD results from atherosclerotic occlusion of the blood vessels causing inte...

Thrombosis is the occlusion of a blood vessel and is responsible for the highest number of deaths worldwide. Its treatment comprises the use of anticoagulants, antiplatelets, and thrombolytics. Although many antithrombotic drugs are currently available, none is completely effective and safe. Plants are a valuable source of compounds with antithromb...

Background Vasculopathy underlies diabetic complications, with perivascular adipose tissue (PVAT) playing crucial roles in its development. However, the changes in the cellular composition and function of PVAT, including the specific cell subsets and mechanisms implicated in type 2 diabetes mellitus (T2DM) vasculopathy, remain unclear. Methods To...

Laser particles (LPs) emitting narrowband spectra across wide spectral ranges are highly promising for high-multiplex optical barcoding. Here, we present LPs based on indium phosphide (InP) nanodisks, operating in the near-infrared wavelength range of 740-970 nm. Utilizing low-order whispering gallery resonance modes in size-tuned nanodisks, we ach...

Purpose To describe an open-source dataset of flat-mounted retinal images and vessel segmentations from mice subject to the oxygen-induced retinopathy (OIR) model. Methods Flat-mounted retinal images from mice killed at postnatal days 12 (P12), P17, and P25 used in prior OIR studies were compiled. Mice subjected to normoxic conditions were killed...

Digital twins represent a key technology for precision health. Medical digital twins consist of computational models that represent the health state of individual patients over time, enabling optimal therapeutics and forecasting patient prognosis. Many health conditions involve the immune system, so it is crucial to include its key features when de...

Ischemic stroke can leave patients with lasting disabilities. Rehabilitation is crucial, but new approaches are needed. One promising avenue is hypoxia exposure therapy. This involves controlled exposure to low oxygen levels. While it may sound counterintuitive, this approach triggers the brain to adapt. Studies suggest hypoxia stimulates the growt...

Sturge–Weber syndrome (SWS) is a rare congenital neurovascular disorder that initially presents with a facial port-wine birthmark (PWB) and most commonly associated with a R183Q somatic mosaic mutation in the gene GNAQ . This mutation is enriched in endothelial cells. Contrast-enhanced magnetic resonance imaging (MRI) diagnoses brain abnormalities...

Morphological changes in retinal vessels are early indicators of cardiovascular and various fundus diseases. However, accurately segmenting thin blood vessels remains a challenge due to the complexity of the vascular structure and the irregularity of pathological features. This paper proposes a dual chain fusion U‐Net (DCFU‐Net) for the precise seg...

Objective This study aims to review and summarize the ultrasound characteristics of alveolar soft part sarcoma (ASPS) in children. Methods We retrospectively analyzed 20 pediatric ASPS cases confirmed by surgery or biopsy at our hospital between January 2014 and January 2024. Clinical data, including age, sex, symptoms, and tumor location, were co...

Background Lung computed tomography (CT) scan image registration is being used for lung function analysis such as ventilation. Given the high sensitivity of functional analyses to image registration errors, an image registration error scoring tool that can measure submillimeter image registration errors is needed. Purpose To propose an image regis...

Breast cancer is a prevalent hormone-dependent malignancy, and estrogens/estrogen receptor (ER) signaling are pivotal therapeutic targets in ER-positive breast cancers, where endocrine therapy has significantly improved treatment efficacy. However, the emergence of both de novo and acquired resistance to these therapies continues to pose challenges...

Introduction: Hypertension or high blood pressure is one of the main health problems in the elderly population in various parts of the world. The elderly are more susceptible to hypertension due to the ageing process that affects the elasticity of blood vessels, as well as increased peripheral resistance. In addition, various risk factors, such as...

This research examines the integration of robotic C-arm technology in angiography, a critical tool for treating cardiac conditions. The robotic C-arm, which includes an X-ray tube, is essential for scanning patients during procedures. The study also investigates the associated risks, specifically in Indonesian hospitals with cardiac facilities. Ang...

Electrospun fibrous scaffolds are widely used in vascular tissue engineering because they are able to mimic the organizational structure and biological function of a natural extracellular matrix. Improving the topological structure and mechanical properties of electrospun fibrous scaffolds is crucial for achieving good interaction between cells and...

Blood vessels in mammalian embryos develop from initial aggregates of endothelial cell (EC) progenitors, which coordinate the opening and stabilization of central vascular lumens, all while under progressively increasing flow and pressure from blood circulation. Mechanical cues exerted by shear stress from the blood flow remodel an initial vascular...

Stroke is a severe medical condition that occurs due to the interruption of blood supply to the brain, either through blockage (ischemic stroke) or rupture of blood vessels (hemorrhagic stroke). With more than 15 million cases each year worldwide, stroke is a leading cause of disability and death, with a significant impact on patients' quality of l...

The blood-brain barrier (BBB) poses a significant challenge in delivering drugs to the central nervous system (CNS), hindering the treatment of neurodegenerative diseases such as epilepsy and Alzheimer's. The BBB's restrictive properties, including tight junctions and efflux transporters, limit the passage of large and small molecular weight drugs,...

Raynaud's phenomenon (RP) is a vasospastic disorder that affects the small blood vessels in the extremities such as the hands, feet, fingers or toes. It is a debilitating condition that can severely impact the patient's quality of life. Botulinum toxin (BTX) has been examined as a treatment option for RP, but its effect has been inconclusive. A sys...

The development of science has a purpose. From a medical point of view, these developments are all about promoting the healthy development of people and allowing people to live a disease-free life. In order to detect these diseases, scientists use different scientific means to detect the patient's physical condition, so as to use the right treatmen...